PlantProductsEssay
Plantproductsareeffectiveinavarietyofdiseaseconditions.Theuseofplantproductsas antioxidantsandimmunomodulatorshasatraditionalhistorynotonlyinIndiabutalsoinalmostall ancientcivilizationsHerbsareconsideredGod'sgifttohumanbeingsintheformofnatural medicines.Thetraditionalpracticeshavebeeninuseforcenturiestocurevariousdiseases.Even thoughthemoderndevelopmentsintherapeuticfieldbroughtaboutarapiddeclineintraditional medicine,butherbalremediesarestillhavinganimportantroleaspotentialsourceoftherapeuticsin healthsystemsacrosstheworld.Therecentgrowthintheknowledgeoffreeradicalsandreactive oxygenspecies(ROS)isproducingamedicalrevolutionshowmorecontent
Increasingevidencesuggeststhatthegenerationoftheseoxygenfreeradicalsplaysanimportant roleinthepathophysiologyofatleastthreediseasestates:ischemiareperfusioninjury,phagocyte–dependentinflammatorydamage,andneurodegenerativedisordersaswellasaging
ElevatedlevelsofROShavebeenimplicatedinnumerouschronicdegenerativediseasessuchas cardiovasculardiseases,neurodegenerativediseases,cancers,type2diabetes,,obesityand hypertension.Theinitiation,promotion,andprogressionofcancer,aswellastheside–effectsof radiationandchemotherapy,havebeenlinkedtotheimbalancebetweenROSandtheantioxidant defensesystemThehighlysignificantcorrelationbetweenconsumptionoffatsandoilsanddeath ratesfromleukemiaandmalignantneoplasiaofthebreast,ovaries,andrectumamongpersonsover 55yearsmaybeareflectionofgreaterlipidperoxidation.ROShavebeenimplicatedinthe inductionandcomplicationsofdiabetesmellitus,age–relatedeyedisease,andneurodegenerative diseasessuchasParkinson'sdisease.
OxidativestressandantioxidantsAroleofoxidativestresshasbeenpostulatedinmanyconditions, includinganthersclerosis,inflammatorycondition,certaincancers,andtheprocessofaging.
Oxidativestressisnowthoughttomakeasignificantcontributiontoallinflammatorydiseases
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