William Haseltine CV - Feb 2024

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WilliamAlanHaseltine

https://www.williamhaseltine.com

EDUCATION:

1966B.A. UniversityofCalifornia(PhysicalChemistry)

1973Ph.D. HarvardUniversity(Biophysics,JamesD.Watson,WalterGilbert)

1973-1975 MassachusettsInstituteofTechnology,PostdoctoralFellow,Centerfor CancerResearch,Cambridge,(DavidBaltimore)

EMPLOYMENT:

2005-present ChairandPresident,ACCESSHealthInternational,Inc.

2003-present Chair,TheHaseltineFoundationforScienceandtheArts

2005-2010 Chairman,HaseltineGlobalHealth,LLC

1993-2004 ChairmanandCEO,HumanGenomeSciences,Inc.

ACADEMICANDMAJORVISITINGAPPOINTMENTS:

2008-2012 MemberoftheBoardofTrustees,InstituteofHumanVirology,University ofMaryland

2008-2010 AdjunctProfessor,InstituteofChemicalEngineering,Universityof Mumbai,India

2006-2008 ChairmanoftheBoardofTrustees,UniversityofCalifornia,Berkley, CenterforSyntheticBiology

2004-2010 AdjunctProfessor,TheScrippsInstituteofMedicalResearch

1989-1995 Professor,DepartmentofCancerBiology,HarvardSchoolofPublicHealth

1988-1995 Professor,DivisionofHumanRetrovirology,Dana-FarberCancerInstitute

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1988-1995 Professor,DepartmentofPathology,HarvardMedicalSchool

1988-1994 HarvardAIDSInstitute:SteeringCommittee

1988-1993 Chief,DivisionofHumanRetrovirology,Dana-FarberCancerInstitute

1981-1988 Chief,LaboratoryofBiochemicalPharmacology,Dana-FarberCancer Institute

1979-1988 AssociateProfessor,DepartmentofPathology,HarvardMedicalSchool, Dana-FarberCancerInstitute

1979-1988 AssociateProfessor,DepartmentofCancerBiology,HarvardSchoolof PublicHealth

1982 VisitingProfessor,UniversityofKyoto

1980-1981 Chief,LaboratoryofMolecularStudiesofCancerCauseandTreatment, Dana-FarberCancerInstitute

1978-1979 AssistantProfessor,DepartmentofCancerBiology,HarvardSchoolof PublicHealth

1975-1978 AssistantProfessor,DepartmentofPathology,HarvardMedicalSchool, Dana-FarberCancerInstitute

1973 VisitingProfessor,UniversityofCopenhagen,InstituteofMicrobiology

TEACHINGEXPERIENCE:

1985-1993

NewPathwaysInstructorforHarvardMedicalSchool

1992 Virology202,MolecularBiologyoftheAIDSVirus,HarvardMedical SchoolandHarvardSchoolofPublicHealth

1990 AIDS1990,ACourseforScandinaviaAIDSresearchMay7-9,1990.

1990 GeneRegulationConference,HarvardAIDSInstitute,November5-7, OrganizerandChair

1981-1988 CellBiology212,AdvancedTopicsinCancerResearch, HarvardMedicalSchoolandHarvardSchoolofPublicHealth

1975-1981 BiologyofCancer,HarvardCollege

1977-1980 BiologyofCancer219,DepartmentofBiophysics,HarvardSchoolof PublicHealth

1976-1978

Microbiology,HarvardMedicalSchool

1969-1973 BiologyandSocialIssues,HarvardCollege

BUSINESSandCONSULTINGEXPERIENCE:

2019-present. EpioneInc.:Founder

2018-present. GracePharmaceuticalsPvtLtd:Director

2016-present X-Vax:Founder

2016-present Demetrix:ChairandFounder

2017-2020 GemeniLtd.:Founder

2008-2020 ProfectusBiosciences,Inc.:Director

2016-2019 ConstructiveBiology:Chair,PresidentandCo-Founder

2016-2018 Atentiv:BoardMember

2008-2017

RelianceIndustries(RIL):InnovationCouncil(India)

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2013-2014 iCloudPharmaceuticals:Director

2009-2013 Genformax:ScientificAdvisor

2012-2013 Pathogenica:ScientificAdvisoryBoard

2007-2010 TheSolenaGroupLtd:Director

2005-2010 IndigeneInc.:Director(India,USA)

2005-2009 CodexisPharmaceuticals:Advisor

2005-2009 CMEA,Inc.:Consultant

2005-2009 TheDNARepairCompany,Inc.:Founder,Chairman

2005-2008 BridgePharmaceuticals,Inc.:Advisor(China)2004-2007

MatrixScientific: ChairmanofAdvisoryBoard(India)1993-2004

HumanGenomeSciences,Inc.: Founder,Chairman,CEO.

1987-2001 HealthCareInvestmentCo:ScientificAdvisoryBoard

1994-2000 Diversa,Inc.:Founder

1992-1998 LeukoSite,Inc.:Founder

1992-1998 ProScript,Inc.(FormerlyMyogenics):Founder

1992-1993 DendreonCorporation,Inc:(FormerlyActivatedCellTherapy)Founder

1990-1993 VirusResearchInstitute,Inc: Founder;ScientificAdvisoryBoard.

1986-1993 SmithKlineSquibb,Consultant.Area:Retrovirusprogram.

1987-1990 Sandoz,Consultant.Area:RetrovirusProgram.

1988-1989 ScheringPlough,Consultant.Area:Retrovirusprogram.

1981-1986 CambridgeBioSciences,Inc:Founder,ScientificAdvisoryBoard.

AWARDSandHONORS:

2013 DistinguishedAchievementAward,LupusFoundationofAmerica

2010 YoungConcertArtistsHonor

2010 LotusClubAwardofDistinction

2010 AIDforAIDS2010MyHeroAward

2005

S.L.E.LupusFoundationGalaScientificHonoree,NewYork

2005 GenomeValleyExcellenceAwardatBioAsia,India

2004 HonoraryDoctorateofScience,UniversityofMaryland

2002 HonoraryDoctorateofScience,UniversityofPortsmouth,UK2003 WashingtonBusinessForward,“The2002ForwardForty”

2001 TimeMagazine“25MostInfluentialGlobalBusinessExecutives”

2001 WashingtonAcademyofSciences“HealthSciencesAwardforScientific Achievement”

2001

KPMG/TechwayMagazineGreaterWashingtonHighTechAward, “TechnologyLegendsAward”

2000 BostonUniversity,F.A.BourkeDistinguishedLectureinBiotechnology 2000MarylandHigh-TechCouncil“FirmoftheYearAward”

1996 KPMGHighTechEntrepreneuroftheYearAward,Washington

1996 Ernst&YoungGreaterWashingtonEntrepreneuroftheYearAward

1995 BurdenCenterAwardforBusinessLeadership

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1996

AmericanAcademyofAchievementGoldenPlateAward

1994 WashingtonianMagazine,"WashingtonBusinessLeaderoftheYear"

1991-1993 BristolMyersSquibbUnrestrictedResearchAward

1987 LeukemiaSocietyofAmerica,Inc.fordistinguishedserviceasamemberof theNationalBoardofTrustees

1986 Governor'sAIDSRecognitionAward

1978-1982 AmericanCancerSocietyFacultyResearchAward

1975-1976 RuthEstrinGoldbergMemorialSocietyAward

1973-1975 HelenHayWhitneyFellow

1964-1966 RegentFellow,UniversityofCalifornia

1965 PhiBetaKappa-Junioryearexceptionalhonor

CURRENTASSOCIATIONSANDBOARDS:

2019-present ChumirFoundationforEthicsinLeadership,InternationalAdvisoryBoard

2019-present Genomes2PeopleResearchProgramAdvisoryBoard

2018-present PatronoftheMetropolitanOpera

2014-present DirectorInternationalChinaAgingIndustryAssociation

2014-present PatronMuseumofModernArt

2014-present PatronMetropolitanMuseum

2014-present PatronoftheWhitneyMuseum

2013-present PatronoftheGuggenheimMuseum

2010-present LifescienceFoundation,Director

2008-present BoardofDirectorsofYoungConcertArtists

2008-present BoardofDirectorsoftheYouthOrchestraoftheAmericas

2008-present HonoraryTrustee,BrookingsInstitution

2007-present LifetimeMemberoftheBoardofGovernors,NewYorkAcademyof Sciences

2006-present Patron,AsiaSociety

2005-present MemberoftheWorldAcademyofArtandScience

2004-present RejuvenationResearch,AssociateEditor

2003-present Member,HaroldPrattAssociates,CouncilonForeignRelations

2002-present Member,AspenInstituteItalia

2001-present Cloning&StemCellsJournal,Member,EditorialBoard

2000-present TheJournalofStemCellResearch,Editor

2011-2018 MemberoftheAdvisoryCounciloftheMaxInstituteofHealthcareand ManagementIndianSchoolofBusiness

2011-2018 MemberoftheAdvisoryBoardofTheRagonInstitute,Cambridge,Mass

2010-2018 AdvisoryBoardoftheMetropolitanOpera

2006-2018 MemberoftheJapanSociety

2009-2017 MemberoftheAdvisoryCounciloftheKochInstituteofIntegrative Biology,MIT

1995-2015 BusinessExecutivesforNationalSecurity

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PROFESSIONALSOCIETYMEMBERSHIPS:

AmericanAssociationfortheAdvancementofScience(AAAS)

AmericanAcademyofAnti-AgingMedicine

AmericanAssociationforCancerResearch(AACR)

AmericanSocietyforBiochemistryandMolecularBiology

NewYorkAcademyofSciences

PhilosophicalSocietyofWashingtonDC

TheAcademyofAmericanPoets

SocietyforTissueEngineeringandRegenerativeMedicine(Founder)

PUBLICATIONS:

Sinceearly2020,WilliamHaseltinehasbeenpublishedwidelyasanauthorityontheCovid-19 pandemicinCNN,WashingtonPost,Forbes,andScientificAmerican.

HeisaregularcontributortoForbes,withover300articlespublishedsince2018,andmaintains abi-monthlycolumnforInsidePrecisionMedicine.

Hehaspublishedover16Op-EdsforTheHill,over20Op-EdsforProjectSyndicate,andover 20articlesforPsychologyToday.

Recent Notable Books

HaseltineWA.AffordableExcellence:TheSingaporeHealthcareStory.BrookingsInstitution Press,RidgeBooksSingapore.2013.

WidenS,HaseltineWA.AgingwithDignity:InnovationandChallengeisSweden-TheVoiceof CareProfessionals.NordicAcademicPress.2017.

HaseltineWA.EverySecondCounts:SavingLiveswithIndia’sEmergencyResponseSystem. BrookingsInstitutionPress,TethysPressIndia.2018.

HaseltineWA. WorldClass:AStoryofAdversity,Transformation,andSuccessatNYU LangoneHealth. FastCompanyPress. 2019.

HaseltineWA,GalianaJ. AgingWell:SolutionstotheMostPressingGlobalHealthChallenges ofAging[hardcover]. PalgraveMacmillan.2019.

HaseltineWA,GalianaJ. AgingWell:SolutionstotheMostPressingGlobalHealthChallenges ofAging[paperback]. GreenleafBookGroup.2020.

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HaseltineWA,DirksenA.VoicesinDementiaCare:ReimaginingtheCultureofCare.Greenleaf BookGroup.2020.

HaseltineWA.StayYoungNavigators:ThePursuitofActiveAgingandSeniorsCaringfor Seniors.ACCESSHealthPress.2020.

HaseltineWA.AFamilyGuidetoCovid:Questions&AnswersforParents,Grandparents,and Children.ACCESSHealthPress.2020.

HaseltineWA.ACovidBackToSchoolGuide:Questions&AnswersforParentsandStudents. ACCESSHealthPress.2020.

HaseltineWA.MyLifelongFightAgainstDisease:FromPolioandAIDStoCovid-19.Mascot Books.2020.

HaseltineWA.ScienceAsASuperpower:MyLifelongFightAgainstDiseaseandtheHeroes WhoMadeItPossible.ACCESSHealthPress.2021.

HaseltineWA.CovidRelatedPostTraumaticStressDisorder,CV-PTSD:WhatItIsandWhatTo DoAboutIt.ACCESSHealthPress.2021.

HaseltineWA.Variants!TheShape-shiftingChallengeofCovid-19.4th Edition.ACCESSHealth Press.2021.

HaseltineWA.NaturalImmunityandCovid-19:WhatitisandHowitCanSaveYourLife. ACCESSHealthPress.2022.

HaseltineWA.Omicron:FromPandemictoEndemic:TheFutureofCovid-19.ACCESSHealth Press.2022.

HaseltineWA.AFamilyGuidetoLongCovid:Questions&Answers.ACCESSHealthPress. 2022.

HaseltineWA.MonoclonalAntibodies:TheOnceandFutureCureforCovid-19.ACCESS HealthPress.2023.

HaseltineWA.TheFutureofMedicine:HealingYourself:RegenerativeMedicinePartOne. ACCESSHealthPress.2023.

HaseltineWA,RathK.ViroidsandVirusoids:Nature’sOwnmRNAs.ACCESSHealthPress. 2023.

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HaseltineWA,ThomasA.CART:ANewCureforCancer,AutoimmuneandInheritedDisease. ACCESSHealthPress.2023.

HaseltineWA,VarnerK.EndingHepatitisC:ASeven-stepPlanforaSuccessfulEradication Program:ARoadmapforEndingEndemicDiseaseGlobally.ACCESSHealthPress.2023.

HaseltineWA,PatarcaR.TheCOVID-19Textbook:Science,MedicineandPublicHealth WoltersKluwer2023.

Original Reports

1. ShirkJ,HaseltineWA,PimentalGC.SintonBandsEvidenceforDeuteratedWateron Mars. Science. 1965. 147:48-49

2. StephansonJC,HaseltineWA,MooreCB.AtmosphericAbsorptionofCO2 Laser Radiation. AppliedPhysicsLetters. 1967. 11:164-166.

3. HaseltineWA.InVitroTranscriptionofEscherichiacoliRibosomalRNAGenes. Nature. 1972. 235:329-333.

4. HaseltineWA,BlockR,GilbertW,WeberK.MSIandMSIIMadeontheRibosomein IdlingStepofProteinSynthesis. Nature.1972. 238:381-384.

5. HaseltineWA,BlockR.SynthesisofGuanosineTetra-andPenta-phosphateRequiresthe PresenceofCodonSpecificUnchargedTransferRibonucleicAcidintheAcceptorSiteof Ribosomes. Proc.Natl.Acad.Sci. 1974. 70:1564-1568.

6. BlockR,HaseltineWA.ThermolobilityoftheStringentFactorinrelMutantsof Escherichiacoli. J.Mol.Biol. 1973. 77:625-629.

7. FreisenJD,FiilNP,ParkerJM,Haseltine,WA. ANewRelaxedMutantofEscherichiacoli withanaltered50sRibosomalSubunit. Proc.Natl.Acad.Sci. 1974. 71:3465-3469.

8. BlockR,HaseltineWA. PurificationandPropertiesofStringentFactor.J.Biol.Chem. 1974. 250:1212-1217.

9. PanetA,HaseltineWA,BaltimoreD,PetersG,HaradaF,DahlbergS.SpecificBindingof TryptophanTransferRNAtoAvianMyeloblastosisVirusReverseTranscriptase. Proc. Natl.Acad.Sci. 1975. 72:2525-2539.

10. HaseltineWA,BaltimoreD.SizeofMurineRNATumorVirus-specificNuclearRNA Molecules. J.Virol. 1976. 19:331-340.

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11. HaseltineWA,KleidD,PanetA,RothenbergE,BaltimoreD.OrderedTranscriptionof RNATumorVirusesbyReverseTranscriptaseInVitro. J.Mol.Biol. 1976. 106:109-131.

12. RoseJ,HaseltineWA,BaltimoreD. 5'-TerminusofMoloneyMurine LeukemiaVirus35s RNAism7G5ppp5'GmpCp. J.Virol. 1976. 20:324-329.

13. PetersG,HaradaF,DahlbergJE,HaseltineWA,PanetA,BaltimoreD.Identificationof RNAPrimerofDNASynthesisofMoloneyMurineLeukemiaVirus.J.Virol.197721:103

14. HaseltineWA,MaxamA,GilbertW TheRousSarcomaVirusGenomeisTerminally Redundantthe5'Sequence. Proc.Natl.Acad.Sci.1977. 74:989-993.

15. CoffinJ,HaseltineWA. TerminalRedundancyandtheOriginofReplicationofRous SarcomaVirusRNA. Proc.Natl.Acad.Sci. 1977. 74:1908-1912.

16. HaseltineWA,PanetA,SmolerD,BaltimoreD,PetersG,HaradaF,Dahlberg J. InteractionofAMVReverseTranscriptaseandtRNAtrp Biochem.1977. 16: 3625-3632.

17. CoffinJ.HaseltineWA. NucleotideSequenceofRousSarcomaVirusRNAatthe InitiationSiteofDNASynthesis. J.Mol.Biol. 1977. 117:805-814.

18. CoffinJM,HagemanRC,MaxamAM,HaseltineWA. StructureoftheGenomeof MoloneyMurineLeukemiaVirus:ATerminallyRedundantSequence. Cell. 1978. 13: 761773.

19. HaseltineWA,KleidDG. AMethodforClassificationof5'TerminalofRetroviruses. Nature. 1978. 273:358-364.

20. TronickSA,CabradillaSA,AaronsonSA,HaseltineWA. 5'TerminalNucleotide SequencesofMammalianTypeCHelperVirusesareConservedintheGenomesof ReplicationDefectiveMammalianTransformingViruses. J.Virol. 1978. 26:570-576.

21. D`AndreaAD,HaseltineWA. SequenceCleavageofDNAbytheAnti-tumorAntibiotics NeocarzinostatinandBleomycin. Proc.Natl.Acad.Sci. 1978. 75:3608-3612.

22. D'AndreaAD,HaseltineWA. ModificationofDNAbyAflatoxinB1 Creates Alkali-LabileLesionsinDNAatPositionsofGuanineandAdenine. Proc.Natl.Acad. Sci.1978. 75:41204124.

23. DesselbergerU,NakajimaK,AlfinoP,PedersenFS,HaseltineWA,HannounC,Palaese P BiochemicalEvidenceThat"New"InfluenzaVirusStrainsinNaturemayAriseby Recombination. Proc.Natl.Acad.Sci. 1978. 75:341-3345.

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24. ReitzMSJr,Wong-StaalF,HaseltineWA,KleidDG,TrainerCD,GallagherRE,Gallo RC. GibbonApeLeukemiaVirusHall'sIsland:NewStrainofGibbonApeLeukemia Virus. JVirol.1979. 29:395-400.

25. HaseltineWA,CoffinJM,HagemanTC. StructureofProductoftheMoloneyMurine LeukemiaVirusEndogenousDNAPolymeraseReaction. J.Virol.1979. 30:375-383.

26. SahaganBG,HaseltineWA. StructuralAnalysisoftheGenomesofWoollyMonkeyand GibbonApeLeukosisViruses. JVirol. 1979. 31:657-667.

27. HaseltineWA,LoKM,D'AndreaAD. PreferredSitesofStrandScissioninDNA Modifiedbyanti-DiolEpoxideofBenzo(a)pyrene. Science. 1980. 209:929-931.

28. HaseltineWA,GordonLK,LindanCP,GrafstromRH,ShaperNL,GrossmanL. CleavageofPyrimidineDimersinSpecificDNASequencesbyaPyrimidineDimer DNA-GlycosylaseofM.luteus Nature. 1980. 285:634-641.

29. RosenbergZR,HaseltineWA. ATransfectionAssayforTransformationbyFeline SarcomaVirusProviralDNA. Virology. 1980. 102:240-244.

30. SahagenBG,HaseltineWA. RelationshipofRetrovirusesIsolatedfromLeukemia TissuestotheWoolly-Monkey-GibbonApeLeukemiaViruses.J.Virology. 1980. 34: 390-401.

31. PedersenFS,HaseltineWA. AnalysisoftheGenomeofanEndogenous,Ecotropic RetrovirusoftheAKRStrainofMice:MicromethodforDetailedCharacterizationof HighMolecular-WeightRNA. J.Virol. 1980. 33:349-365.

32. RosenbergZF,PedersenFS,HaseltineWA. ComparativeAnalysisoftheGenomesof FelineLeukemiaViruses. J.Virol. 1980. 35:542-546.

33. ClementsJE,PedersenFS,NarayanO,HaseltineWA. GenomicChangesAssociatedwith AntigenicVariationofVisnaVirusduringPersistentInfection. Proc.Natl.Acad.Sci. 1980. 77:4454-4458.

34. PedersenFS,BuchhaganDL,ChenCY,HaysEF,HaseltineWA. Characterizationof VirusProducedbyaLymphomaInducedbyInoculationofAKRMCF-247Virus. J. Virol. 1980. 35:211-218.

35. GordonLK,HaseltineWA. ComparisonoftheCleavageofPyrimidineDimersbythe BacteriophageT4andM.luteusUV-SpecificEndonucleases. J.Biol.Chem. 1980. 255: 1204712050.

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36. GrunbergSM,HaseltineWA. UseofanIndicatorSequenceofHumanDNAtoStudy DNADamagebyMethylbis(2-chloreothyl)amine. Proc.Natl.AcadSci. 1980. 77: 6546-6550.

37. BuchhaganDL,PedersenFS,CrowtherRL,HaseltineWA. MostSequenceDifferences BetweentheGenomesoftheAKVVirusandaLeukemogenicGross AVirusPassagedIn VitroarelocatedNearthe3'Terminus. Proc.Natl.Acad.Sci. 1980. 77:4359-4363.

38. PedersenFS,CrowtherRL,TenneyDY,ReimoldAM,HaseltineWA.Novel LeukemogenicRetrovirusesIsolatedfromCellLineDerivedfromSpontaneousAKR Tumor Nature. 1981. 292:167-170.

39. MartinRF,HaseltineWA.RangeofRadiochemicalDamagetoDNAwithDecayof Iodine125.Science. 1981. 213:896-898.

40. RosenbergZF,CrowtherRL,EssexM,JarrettO,HaseltineWA. IsolationVia TransfectionofFelineLeukemiaVirusesfromDNAofNaturallyOccurringFeline Lymphomas. Virology. 1981. 115:203-210.

41. RosenbergZF,SahaganBG,SnyderHW,WorleyMB,EssexM,Haseltine WA. BiochemicalCharacterizationofCellstransformedViaTransfectionbyFeline SarcomaVirusProviralDNA. JVirol.1981. 38:782-788.

42. RosenbergZF,SahagenBG,WorleyMB,EssexM,HaseltineWA. Transformationwith SubgenomicFragmentsofFelineSarcomaVirusProviralDNA. Virology 1981. 112: 496-504.

43. BerlinV,HaseltineWA. ReductionofAdriamycintoaSemiquinoneFeeRadicalby NAHPHCytochromeP-450ReductaseProducesDNACleavageinaReactionMediated byMolecularOxygen. J.Biol.Chem. 1981.256:4747-4756.

44. GordonLK,HaseltineWA. EarlyStepsofExcisionRepairofCyclobutanePyrimidine DimersbytheMicrococcusLuteusEndonuclease;AThreeStepIncisionModel. J.Biol. Chem. 1981. 256:6608-6616.

45. LipkeJA,GordonLK,Brash,DE,HaseltineWA. DistributionofUltravioletLight InducedDamageinaDefinedSequenceofHumanDNA: DetectionofAlkalineSensitive LesionsatPyrimidine-Nucleoside-CytidineSequences. Proc.Natl.Acad.Sci. 1981. 78: 33883392.

46. GordonLK,HaseltineWA.QuantitationofCyclobutanePyrimidineDimerFormationin DoubleandSingleStrandedDNAFragmentsofDefined Sequences. RadiationResearch. 1982. 89:99-112.

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47. Royer-PokoraB,GordonLK,HaseltineWA. UseofExonucleaseIIItoDeterminetheSite ofStableLesionsinDefinedSequencesofDNA;TheCyclobutanePyrimidineDimerand cisandtransDichloradiamminePlatinumIIExamples. NucleicAcidsResearch. 1982. 9:4595-4609.

48. PedersenFS,CrowtherRL,HaysEF,NowinskiRC,HaseltineWA. Structureof RetroviralRNAsProducedbyCellLinesDerivedfromSpontaneous Lymphomasof AKRMice. J.Virol. 1982. 41: 18-29.

49. LenzJ,CrowtherR,StraceskiA,HaseltineWA. NucleotideSequencesoftheAkvenv Gene. J.Virol. 1982. 42:519-529.

50. TrusMD,SodroskiJG,HaseltineWA. IsolationandCharacterizationofaHumanLocus HomologoustotheTransformingGene(v-fes)ofFelineSarcomaVirus. J.Biol. Chem. 1982. 257:2730-2733.

51. KrossJ,HennerWD,HechtSM,HaseltineWA. SpecificityofDeoxyribonucleicAcid CleavagebyBleomycin,PhleomycinandTallysomycin. Biochem. 1982. 21:4310-4318.

52. KrossJ,HennerWD,HaseltineWA,RodriguezL,LevinM,HechtSM.StructuralBasis fortheDNAAffinityofBleomycins. Biochem.1982. 21:3711-3721.

53. BrashDE,HaseltineWA.UltravioletLightInducedMutationHotspotsOccuratDNA DamageHotspots. Nature. 1982. 298:189-192.

54. LenzJ,CrowtherR,KlimenkoS,HaseltineWA.MolecularCloningofaHighly Leukemogenic,EcotropicRetrovirusfromanAKRMouse. J.Virol.1982. 43:943-951.

55. HennerWD,GrunbergSM,HaseltineWA. SitesandStructureofGammaRadiation InducedDNAStrandBreaks. J.Biol. Chem.1982. 257:11750-11754.

56. FranklinWA,LoKM,HaseltineWA.AlkalineLabilityofFluorescentPhotoproductsin UltravioletLight-irradiatedDNA. J.Biol.Chem. 1982. 257:13535-13543.

57. HennerWD,RodriguezLO,HechtSM,HaseltineWA. GammaRayInduced DeoxyribonucleicAcidStrandBreaks:3'GlycolateTermini.J.Biol.Chem.1983. 258: 711-713.

58. Romet-LemoneJL,McLaneMF,ElfassiE,HaseltineWA,AzocarJ,EssexM. Hepatitis B.VirusInfectioninaHumanLymphoblastoidCellCulture. Science. 1983. 221: 667-669.

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59. LenzJ,HaseltineWA. LocalizationoftheLeukemogenicDeterminantsofSL3-3,an Ecotropic,XC-Positive,MurineLeukemiaVirusofAKROrigin. J.Virology. 1983. 47: 317328.

60. HennerWD,GrunbergSM,HaseltineWA.EnzymeActionat3'TerminiofIonizing Radiation-inducedDNAStrandBreaks. J.Biol.Chem.1983. 258:15198-15205.

61. LenzJ,CelanderD,CrowtherRL,PatarcaR,PerkinsDW,SheldonA,HaseltineWA. EnhancerSequencesthatDetermineLeukemogenicityofaMurineRetrovirus. Nature. 1984. 308:467-470.

62. Royer-PokoraB,PedersenW,HaseltineWA. BiologicalandBiochemical CharacterizationofanSV40TransformedXerodermaPigmentosumCellLine. Exp. Cell Res. 1984. 151:408-420.

63. FreiE,RosowskyA,WrightJE,CucchiCA,LippkeJA,ErvinTJ,JolivetJ,Haseltine WA. DevelopmentofMethotrexateResistanceinaHumanSquamousCellCarcinomaof theHeadandNeckinCulture. Proc.Natl.Acad.Sci. 1984. 81:2873-2877.

64. ElfassiE,Romet-LemonneJL,EssexM,Frances-McLaneM,HaseltineWA. Evidenceof ExtrachromosomalFormsofHepatitisBViralDNAinBoneMarrowCultureObtained fromaPatientRecentlyInfectedwithHepatitisBVirus. Proc.Natl.Acad.Sci. 1984. 81: 3526-3528.

65. DeLucaD,DoetschPW,HaseltineWA. ConstructionofaMammalianExpressionVector fortheE.coliuvrA,b,andCGenes. Plasmid. 1984. 11:253-259.

66. SodroskiJG,GohWC,HaseltineWA. TransformingPotentialoftheHumancfps/fes Locus. Proc.Natl.Acad.Sci. 1984. 81:3039-3043.

67. SodroskiJG,TrusM,PerkinsD,PatarcaR,Wong-StaalF,GelmanE,GalloR,Haseltine WA. RepetitiveStructureintheLongTerminalRepeatElementofaTypeIIHumanT CellLeukemiaVirus. Proc.Natl.Acad.Sci. 1984. 81:4617-4621.

68. FranklinWA,HaseltineWA. RemovalofUVLight-inducedPyrimidine-Pyrimidone (6-4)ProductsfromEscherichiacoliDNARequirestheuvrA,uvrB,anduvrCGene Products. Proc.Natl.Acad.Sci.1984. 81:3821-3824.

69. SageE,HaseltineWA. HighRatioofAlkaliSensitiveLesionstoTotalDNA ModificationInducedbyBenso(a)pyrenediolepoxide. J.Biol.Chem.1984. 259: 11098-11102.

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70. SodroskiJG,RosenC,HaseltineWA. Trans-actingTranscriptionalActivationofthe LongTerminalRepeatofHumanTLymphotropicVirusesinInfectedCells. Science. 1984. 225:381385.

71. HaseltineWA,SodroskiJG,PatarcaR,BriggsD,PerkinsD,Wong-StaalF Structureof the3'TerminalRegionofTypeIIHumanTLymphotropicVirus:EvidenceforaNew CodingRegion. Science.1984. 225:419-421.

72. SodroskiJG,PatarcaR,PerkinsD,BriggsD,LeeTH,EssexM,ColiganJ,WongStaalF, GalloR,HaseltineWA. TheSequenceoftheEnvelopeGlycoproteinGeneofTypeII HumanTLymphotropicVirus. Science.1984. 225:421-424.

73. Royer-PokoraB,HaseltineWA. IsolationofUVResistantRevertantsfromaXeroderma PigmentosumComplementationGroupACellLine. Nature.1984. 311:390-392.

74. LeeTH,ColiganJE,SodroskiJG,HaseltineWA,SalahuddinSZ,Wong-StaalF,Gallo RC,EssexM. AntigensEncodedbythe3'-TerminalRegionofHumanT-CellLeukemia Virus:EvidenceforaFunctionalGene. Science.1984. 226:57-61.

75. PatarcaR,HaseltineWA. SequenceSimilarityAmongRetroviruses. Nature.1984. 309: 728.

76. PatarcaR,HaseltineWA. SimilaritiesAmongRetrovirusProteins.Nature.1984. 312: 496.

77. CelanderD,HaseltineWA. TissueSpecificPreferenceasaDeterminantofCellTropism andLeukemogenicPotentialofMurineRetroviruses.Nature.1984. 312:159-162.

78. JosephsJF,WongStaalF,ManzariV,GalloRC,SodroskiJG,TrusM,PerkinsD,Patarca R,HaseltineWA.LongTerminalRepeatStructureofanAmericanIsolateofHumanT CellLeukemiaVirus. J.Virology. 1984. 139:340-345.

79. SodroskiJG,RosenCR,Wong-StaalF,PopovicM,AryaS,GalloRC,HaseltineWA. Trans-actingTranscriptionalActivationoftheLong TerminalRepeatofHumanTCell LeukemiaVirusTypeIII(HTLV-III). Science. 1985. 227:171-173.

80. RosenCA,SodroskiJG,KettmanR,BurnyA,HaseltineWA. Trans-activationofthe BovineLeukemiaVirusLongTerminalRepeat. Science.1985. 227:320-322.

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154. CaputoA,SodroskiJG,HaseltineWA.ConstitutiveExpressionofHIV-1tatProteinin HumanJurkatTCellsUsingaBKVirusVector.JournalofAcquiredDeficiency Sydromes.1990.3:373-379.

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167. LuY,TouzjianN,DorfmanT,SodroskiJ,HaseltineW. TheNFkBindependentcisacting sequencesinHIV-1LTRresponsivetoT-cellactivation. JournalofAcquiredImmune DeficiencySyndrome. 1991. Volume4. 2:173-177.

168. PrasadV,MyrickK,HaseltineW,GoffS. ExpressionofEnzymaticallyActiveReverse TranscriptaseofSimianImmunodeficiencyVirusinBacteria: SensitivitytoNucleotide AnalogueInhibitors. 1990.JournalofVirology. 179: 896-900.

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197. Überla,K,LuY,ChungE,andHaseltineWA. CharacterizationoftheNF-kappaBp65 promotor. J.Acquir.Immun.Def.Synd.1993.6:227-230.

198. Zazopoulos,EandHaseltineWA. Effectofnefallellesonreplicationofhuman immunodeficiencyvirustype1. J.Virology. 1992.194:20-27

199. YaoX-J,GarzonS,BoisvertF,HaseltineWH,andCohenE. TheeffectofvpuonHIV-1 InducedSyncytiaFormation.J.Acquir.Immun.Def.Synd.1993.6:135-141.

200. ShilatifardA,MerkleRK,HellandDE,WellesJL,HaseltineWAandCummingsRD. Complex-typeN-LinkedOligosaccharidesofgp120fromHumanImmunodeficiency VirusType1ContainSulfatedN-Acetylglucosamine. J.Virology.1993.67:943-952.

201. LanghoffE,KallandKH,andHaseltineWH. Earlymolecularreplicationofhuman immunodeficiencyvirustype1inculturedbloodderivedThelperdendriticcells. J.Clin. Inves.1993.91:2721-2726.

202. Göttlinger,H.G.,Dorfman,T.,Cohen,E.A.,andHaseltine,W.A.Vpuproteinofhuman immunodeficiencyvirustype1enhancesthereleaseofcapsidsproducedby gag gene constructsofwidelydivergentretroviruses.Proc.Natl.Acad.Sci.USA1993. 90:7381-7385.

203. McGuireK,CurtissVS,LarsonEL,HaseltineWA. InfluenceofhumanT-cellleukemia virustype1taxandrexoninterleukin-2geneexpression. J.Virol.1993.67:1590-1599. 204. MarascoWA,HaseltineWA,andChenSY Design,IntracellularExpression,and ActivityofaHumanAnti-HIV-1gp120SingleChainAntibody Proc.Natl.Acad.Sci. U.S.A.,90:7889-7893,1993.

205. Dorfman,T.,Luban,J.,Goff,S.P.,Haseltine,W.A.,andGöttlinger,H.G.Mappingof functionallyimportantresiduesofacysteine-histidineboxinthehuman immunodeficiencyvirustype1nucleocapsidprotein.J.Virol.1993.67:6159-6169.

206. N.Papadopoulos,N.C.Nicolaides,Ying-FeiWei,S.M.Ruben,K.C.Carter,C.A. Rosen,W A.Haseltine,R.D.Fleischmann,C.M.Fraser,M.D.Adams,J.C.Venter,S. R.Hamilton,G.M.Petersen,P.Watson,H.T.Lynch,P. Peltomaki,Jukka-Pekka Mecklin,A.delaChapelle,K.W.Kinzler,B.Vogelstein. Mutationofa mutLHomolog inHereditaryColonCancer.Science 1994. Vol.263;pp1625-

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207. N.Papadopoulos,N.C.Nicolaides,Ying-FeiWei,S.M.Ruben,K.C.Carter,C.A. Rosen,W A.Haseltine,R.D.Fleischmann,C.M.Fraser,M.D.Adams,J.C.Venter,S. R.Hamilton,G.M.Petersen,P Watson,H.T.Lynch,P Peltomaki,Jukka-Pekka Mecklin,A.delaChapelle,K.W Kinzler,B.Vogelstein. MutationsofTwo mutL Homologs, hPMS1 and hPMS2,inHereditaryNonpolyposisColonCancer

208. Wei,Y.F.,Robins,P.,Carter,K.,Caldecott,K.,Pappin,D.J.C.,Haseltine,W.A.,Lindahl, T. MolecularCloningandExpressionofHumancDNAsEncodingaNovelDNALigase IVandDNALigaseIII,anEnzymeActiveinDNARepairandRecombination. MolecularandCellularBiology.June1995.Vol.15,No.6,pp.3206-3216.

209. Uberla,K.,Stahl-Hennig,C.,Bottiger,D.,Matz-Rensing,K.,Kaup,F.J.,Li,J.,Haseltine, W.A.,Fleckenstein,B.,Hunsmann,G.,Oberg,B.,SodroskiJ. Animalmodelforthe therapyofacquiredimmunodeficiencysyndromewithreversetranscriptaseinhibitors. Proc.Natl.Acad.Sci.USA. August1995. Vol.92,pp.8210-8214.

210. Wei,Y.F.,Robins,P.,Carter,K.,Pappin,D.J.C.,Wang,R.P.,Shell,B.K.Schar,Primo,S., Nash,R.,Cadecott,K.,Barnes,D.E.,Haseltine,W.A.,Lindahl,T. Molecularcloning andexpressionofthehumancDNAe3ncodingDNAligaseIII,anenzymeactiveinDNA repairandrecombination. JournalofBiologicalChemistry. November29,1996. Vol. 271,No.48,pp.30375-30380.

211. Haseltine,W.A.DiscoveringGenesforNewMedicines. ScientificAmerican. March 1997. Vol.276,No.3,pp.92-97.

212. Haseltine,W.A.ThePowerofGenomicstotransformthebiotechnologyindustry Nature Biotechnology May1998.Supplement.pp.25-27.

213. Friborg,J.,Ladha,A.,Göttlinger,H.,Kalland,K.,Haseltine,W.A.,andCohen,E.A. Functionalanalysisofthephosphorylationsitesonthehumanimmunodeficiencyvirus type1Vpuprotein.JournalofAcquiredImmuneDeficiencySyndromes,January1, 1995.Vol8.pp.10-22

214. Lavallée,C.,Yao,X.J.,Ladha,A.,Göttlinger,H.,Haseltine,W.A.,andCohen,E.A. RequirementofPr55gag precursorfortheincorporationoftheVprproductintohuman immunodeficiencyvirustype1viralparticles.JournalofVirology March1994. Vol.3. pp.1926-1934.

215. Dorfman,T.,Mammano,F.,Haseltine,W.A.,andGöttlinger,H.G.Roleofthep17matrix proteininthevirionassociationofthehumanimmunodeficiencyvirustype1envelope glycoprotein. JournalofVirology,March1994.Vol.3.pp.1689-1996.

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216. Patarca,Roberto.,Haseltine,W.A.StructuralflexibilityoftheSARS-CoV-2genome relevanttovariation,replication,pathogenicity,andimmuneevasion.BioRxiv.December 20,2021.DOI:https://doi.org/10.1101/2021.12.20.473542

217. Patarca,Roberto.,Haseltine,W.A.Circularizationviacomplementarysequencesinthe5' and3'terminimayfacilitatereplicationofSARScoronaviruses.Authorea.January04, 2022.DOI:10.22541/au.164132044.46753705/v1

218. Patarca,Roberto.,Haseltine,W.A.IntragenomicrearrangementsofSARS-CoV-2and otherβ-coronaviruses.BioRxiv March3,2022.DOI: https://doi.org/10.1101/2022.03.07.483258

219. Patarca,Roberto.,Haseltine,W.A.,FortyyearsofHIVresearchinspiresthedevelopment ofSARS-CoV-2therapy, Journal of Molecular Cell Biology,2023.DOI: https://doi.org/10.1093/jmcb/mjad065

220. Patarca,Roberto.,Haseltine,W.A.,BioinformaticsInsightsonViralGeneExpression Transactivation:FromHIV-1toSARS-CoV-2, Preprints, 2024.DOI: https://10.20944/preprints202401.2016.v1

Books and Monographs

1b. HaseltineWA,IN:JeffreyMiller. ExperimentsinMolecularGenetics. ColdSpringHarbor, NewYork: 1972. 326-347.

2b. HaseltineWA,BlockR. InVitroSynthesisofppGppandpppGpp. In:TissiersN,Normura, LengylP,eds. Ribosomes. ColdSpringHarborPress,NewYork:1973. 747-761.

3b. HaseltineWA,BlockR,WeberK,GilbertW. MSIandMSIIareMadeontheRibosomein andIdlingStepofProteinSynthesis. IN:ZubayG,MarmurJ,eds. PapersinBiochemical Genetics. NewYork:Holt,Reinhart,Winston,Inc. 1973. 570.

4b. BesmerP,SmotkinD,HaseltineWA,BaltimoreD. MechanismofInductionofRNATumor VirusesbyHalogenatedPyrimidines. ColdSpringHarborLaboratoryofQuant.Bio.NewYork: 1974. 1103-1107.

5b. HaseltineWA,BaltimoreD. InVitroReplicationofRNATumorVirus. IN:BaltimoreD, HuangA,FoxCF,eds. AnimalVirology,ICN-UCLASymposiaonMolecularandCellular Biology. NewYork:AcademicPress.1976. IV:175-213.

6b. HaseltineWA,KleidD,PedersenFS. AnalysisofRNATumorVirusGenomes.IN:Kalter S,HellmanA,GruberJ,eds. AdvancesinComparativeLeukemiaResearch. NorthHolland: BiomedicalPress.1977. 437-442.

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7b. HaseltineWA,KleidD. ANewLookattheStructureofPrimateTypecViralGenomes.IN: KalterS,HellmanA,GuberJ,eds.PrimatesandHumanCancer DHEW(NIH).1977. 185195.

8b. HaseltineWA,PedersenFS,SahaganBG,RosenbergZF ComparativeAnalysisofRNA TumorVirusGenomes. IN:NethR,GalloR,eds.ModernTrendsinHumanLeukemiaIII,1978.

9b. GrossmanL,RiazuddinS,HaseltineWA,LindanK. NucleotideExcisionRepairof DamagedDNA. ColdSpringHarborLaboratoryofQuantBiolSymp.1979. 43:947-955.

10b. HaseltineWA,CoffinJA.InVitroStudiesoftheReplicationofMoloneyMurineLeukemia Virus. ColdSpringHarborLaboratoryofQuantBiolSymp.1979. 43:841-849.

11b. Pedersen FS, Haseltine WA. A Micromethod for Detailed Characterization of High Molecular WeightRNA. IN:GrossmanL,MoldaveK,eds.MethodsinEnzymology.New York. AcademicPress.1980. 65.

12b. HaseltineWA,LindanCP,D'AndreaAD,JohnsrudL. TheuseofDNAFragmentsof DefinedSequencefortheStudyofDNAandRepair IN:GrossmanL,MoldaveK,eds.Methods inEnzymology NewYork.AcademicPress,1980. 65:235-248.

13b. ClementsJE,PedersenFS,NarayanO,HaseltineWA. MutationasaMechanismfor EscapefromImmuneSuppression:theVisnaVirusExample.IN:VirusesinNaturallyOccurring Cancers. NewYork:ColdSpringHarborConferencesonCellProliferation.1980. 7:953-967.

14b. SahaganBG,RosenbergZR,HaseltineWA. RestrictionEnzymeAnalysisoftheFeline SarcomaVirusProvirusinMurineFibroblastsTransformedbyTransfection. IN:HardyWDJr, Essex,McClellandAJ,eds.FelineLeukemiaVirus.NorthHolland.1980. 345-352.

15b. RosenbergZF,PedersenFS,HaseltineWA.ComparativeAnalysisoftheGenomesof FelineLeukemiaViruses.IN:HardyWDJr,EssexM,McClellandAJ,eds.FelineLeukemia Virus.NorthHolland:1980. 355-359.

16b. ClementsJE,DAntoniaN,NaqrayanO,PedersenFS,HaseltineWA. AntigenicVariation ofVisnaVirus.IN:FildsB,JaenischR,FoxCT,eds.AnimalVirusGenetics,ICN-UCLA SymposiaonMolecularandCellularBiology NewYork:AcademicPress.1980. XVIII.

17b. GrafstrnomR,SnaperN,GrossmanL,HaseltineWa. IncisionofPyrimidineDimer ContainingDNAbySmallMolecularWeightEnzymes.IN:SeeburgE,eds.Chromosome DamageandRepair PlenumPress.1980.

18b. GrunbergerD,BelandFA,DippleA,HaseltineWA,PoirierMO,SingerB.Quantitationof DNADamage. J.SupramolecularStructureandCellularBiochemistry.

27

19b. Haseltine WA, Lippke JA, Gordan LK,BrashDE. DetectionorAlkalineSensitiveLesions Induced by Ultraviolet LightatPyrimidine-CytosineSequencesinDNA.IN:HarrisC,CeruttiP, eds. Proceedings of the ICN-UCLA Symposia on Mechanisms of Chemical Carcinogenesis. 1982. 2:363-449.

20b. HaseltineWA,GordonLR,LindanC,LippkeJ,BrashD,LoRM,Royer-PokoraB. New Approaches to DNA Damage and Repair: The Ultraviolet Light Example. IN: Lemontt JF, Generoso WM,eds.MolecularandCellularMechanismsorMutagenesis. NewYork:Plenum Press.1982. 315-332.

21b. LippkeJ,HaseltineWA. TheHumanAlphoidSequenceasanIndicatorofDNA Damage inIntactCells. IN:HanawaltlPC,FriedbergEC,eds.sDNARepair:ALaboratoryManualof ResearchProcedures.NewYork:MarcelDekker,Inc.1983. 2:187-198.

22b. HaseltineWA. UltravioletLightRepairandMutagenesisRevisited. Cell. 1983. 33:1317.

23b. FranklinWA,HaseltineWA. TheUseofPost-labelingMethodstoDetectand Characterize InfrequentBaseModificationsinDNA. IN:HanawaltPC,FriedbergC,Eds. DNA Repair: A Laboratory Manual of Research Procedures. New York: Marcel Dekker, Inc. 1983. 2:161-171.

24b. HaseltineWA,BrashDE,LippkeJA,BrashDE,LoKM. NewApproachestoDNA Damage and Repair. IN: RT Schimke, ed. Gene Amplification. Cold Spring Harbor. 1982. 263-272.

25b. HaseltineWA,FranklinWA,LippkeJA,BrashDE,LoKM.PossibleBiological Significance of a Novel Ultraviolet Light Induced DNA Photoproduct. IN: Perspectives on Genes and the Molecular Biology of Cancer Texas: Robberson Saunders, ds. Raven Press. 1982. 291-298.

26b. LoKW,BrashDE,FranklinWA,LippkeJA,HaseltineWA. UVLightInducedSequence SpecificDNADamageandMutagenesis. IN:HumanCarcinogenesis. 1982. 281-299.

27b. Lo KW, Brash DE,FranklinWA,LippkeJA,HaseltineWA. StudiesofDNADamageand Mutagenesis by Ultraviolet Light. IN: Genes and Proteins in Oncogenesis. Academic Press, N.Y 1982. 41-53.

28b. HaseltineWA,LenzJ,CrowtherR. DeterminationofVirulencePropertiesofLeukemia Viruses. IN:ModernTrendsinHumanLeukemiaVirus.1982. 28:451-455.

29b. LoKM,FranklinWA,LippkeJA,HennerWD,HaseltineWA. NewMethodsforthe DetectionofDNADamagetoHumanCellularDNAbyEnvironmentalCarcinogensand AntitumorDrugs. IN:BanburyReport13.ColdSpringHarbor.1982. 253-263.

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30b.HaseltineWA,FranklinWA,LippkeJA. NewMethodsforDetectionofLowLevelsof DNADamageinHumanPopulations. IN:Env.HealthPerspectives.1983. 48:29-41.

31b. SodroskiJG,LenzJR,HaseltineWA.ReflectionsandSpeculationsRegardingMechanisms ofCarcinogenesis. Inserm.1983. 117:189-216.

32b. Haseltine WA. Site Specificity of Ultraviolet Light Induced Mutagenesis. IN: UCLA Symposia onMolecularandCellularBiology,NewSeries.eds.ECFriedberg,BABridgesLiss, NewYork. 1983. 11:2-33.

33b. SodroskiJG,PatarcaR,LenzJ,TrusM,CrowtherR,PerkinsD,GalloR,Wong-StaalF, Josephs S, Gelman E, Haseltine WA. LTR Regions of Murine Leukemia Virus and Human T Cell Leukemia Virus as Potential Leukemogenic and Pathogenic Determinants. IN: Human T Cell Leukemia/LymphomaVirus.eds.RCGallo,MEEssex,LGross.ColdSpringHarborLabs. 1983. 149-155.

34b. Haseltine WA. Sodroski JG,PatarcaR. StructureandFunctionoftheGenomeofHTLV. IN: CurrentTopicsinMicrobiologyandImmunology ed.PKVogt.Springer-Verlag,Germany 1984. 115:177-209.

35b. BisterK,BurnyAL,CroceCM,HaseltineWA,HaymanMJ,HaywardWS,KleinG, MoellingK,NethRD,PragnellIB,RowleyJD. GenesandVirusesAbletoTransform HematopoieticCells. IN:Leukemia,ed.ILWeissman.Springer-Verlag,Germany 1983. 275292.

36b. Haseltine WA, SodroskiJG,RosenCA. StructureandFunctionofHumanLeukemiaand AIDS Viruses.IN:RetrovirusesinHumanLymphoma/Leukemia,ed.M.Miwa.JapanSci.Soc. Press,Tokyo. 1985. 187-196.

37b. HaseltineWA,SodroskiJG,RosenCA.ControlofGeneExpressionandtheReplication and Pathogenesis of Retroviruses. IN:ImportantAdvancesinOncology J.B.Lippincott,PA. 1986. 159-172.

38b. HaseltineWA,SodroskiJG,RosenCA. ProgressandPuzzles:TheMolecularBiologyof HTLV-III.IN:AIDS:ModernConceptsandTherapeuticChallenges.ed.S.Broder.Marcel Dekker,Inc.,NewYork. 1986. 53-62.

39b. HaseltineWA,SodroskiJG,RosenCA,GohWC,DaytonAI,Celander DW TransactivatorGenesofHTLV-I,II,andIII. IN:OncogenesandGrowthControl.eds.P Kahn,T Graf.1986,247-252. Publishers,Springer-Verlag,Heidelberg,FRG.

40b. HaseltineWA,SodroskiJG. CellMembraneFusionMediatedbytheEnvelope GlycoproteinsasthePrimaryEffectorofAIDSVirusCytopathicity IN:Acquired

29

ImmunoDeficiencySyndrome. 1986. 47-56. (ProceedingsoftheIIInternationalConferenceon AIDS,Paris). Publisher,Elsevier.

41b.HaseltineWA. ReplicationandPathogenesisofHumanRetroviruses. IN: Viral CarcinogenesisFunctionalAspects. 1986. 100-112. (ProceedingsoftheAlfredBenzon Symposium). Publisher,Munksgard,Copenhagen.

42b. SodroskiJG,GohWC,RosenCA,TerwilligerE,DaytonAI,CampbellK,HaseltineWA. AFunctionalAnalysisoftheHTLV-IIIEnvelope:ImplicationsforPathogenesis,Therapyand Prophylaxis.1986.(ProceedingsofColdSpringHarborMeeting,N.Y.).

43b. SodroskiJG,HaseltineWA. TheAIDSVirus: PuzzlesfortheMolecularBiologist. IN: AIDSINOURLIVES: PersonalSocial,andMedicalIssues(editor,EarlHansonPPI Publishing,1989),pp7-34.

44b. HaseltineWA. MolecularApproachesToPreventiveandTherapeuticInterventionfor AIDS. IN:RetrovirusesofHumanAIDSandRelatedAnimalDiseases. 1986. 5860. (ProceedingsofColloqueDesCentGardes).Publisher,PasteurVaccins,France.

45b. SodroskiJG,KowalskiMK,DorfmanT,BasiripourL,RosenCA,HaseltineWA. HIV Envelope-CD4InteractionNotInhibitedbySyntheticOctapeptides. TheLancet.1987. 14281429.

46b. SodroskiJG,HaseltineWA,RosenCA,PotzJ,BasiripourL,DorfmanT,KowalskiM. Structure-FunctionAnalysisoftheHumanImmunodeficiencyVirusEnvelopeGlycoprotein. 1987.(ProceedingsofNIHWorkshoponPeptide"T").

47b. Haseltine WA, Sodroski JG, Rosen CA. Replication and Pathogenesis of the Human TCell Leukemia/Lymphotropic Retrovirus. IN: Modern Trends in Human Leukemia VII. Springer-Verlag,Germany 1987. 395-403.

48b. HaseltineWA. ObservationsfromtheFront. IN:SIDA:EpidemiesetSocietes. 1987. 5461.Publisher,FondationMarcelMerieux. (ProceedingsoftheFondationMarcelMerieux, Annecy).

49b. HaseltineWA,SodroskiJ,TerwilligerE. ReplicationandPathogenesisofHIV-1 RetrovirusRelevanttoDrugDesign. IN:RetrovirusesandDisease. 1989. 159-181. Publisher, AcademicPress. (ProceedingsofInternationalSymposiumonMedicalVirology,Irvine,CA).

50b. HaseltineWA,KowalskiM,SodroskiJG. TheStructureandFunctionoftheEnvelope GlycoproteinoftheAIDSVirus. 1988. Publisher,PasteurVaccins. (ProceedingsoftheCent GardesMeeting,Paris).

30

51b. HaseltineWA. ARationalApproachToChemotherapyofAIDS. IN:HIVandOther HighlyPathogenicViruses. 1988. 25-32.

52b. EncyclopediaAmericana. AIDSArticle. 1988Edition. Publisher,GrolierIncorporated, Danbury,Connecticut.

53b.SodroskiJG,KowalskiMM,HaseltineWA. StructureandFunctionoftheHuman ImmunodeficiencyVirusEnvelope: ImplicationsforVaccineDevelopment. 1988. IN:AIDS Vaccine:BasicResearchandClinicalTrials. 1988.

54b. SodroskiJG,HaseltineWA. TheMolecularBiologyofHIVReplicationand Pathogenesis. IN:AIDS1988(editor,RuthKulstad,AmericanAssociationfortheAdvancement ofScience,1988)pp.385-400.

55b. HaseltineWA,Wong-StaalF TheMolecularBiologyoftheHumanImmunoDeficiency Virus. ScientificAmerican. 1988. 256:52-62.

56b. HaseltineWA. ReplicationandPathogenesisoftheAIDSVirus. (PlenaryLecture presentedattheIVthInternationalConferenceonAIDS,Stockholm,Sweden). Journalof AcquiredImmuneDeficiencySyndromes.1988. 1:217-240.

57b. HaseltineWA,TerwilligerEF,RosenCA,SodroskiJG. StructureandFunctionofHuman PathogenicRetroviruses. IN:RetrovirusBiology:AnEmergingRoleinHumanDisease. PublishedbyMarcelDekker,Inc. 1988.

58b. HaseltineWA. CurrentandFutureProspectsforAnti-ViralAIDSDrug Development. (ProceedingsoftheSymposiumBiotechnologyandtheAIDSChallengein Massachusetts:ASymposiumReport). April,1989. 87-89. Sponsors:MassachusettsCenters forExcellenceCorp.,MassachusettsBiotechnologyResearchInstitute,Universityof MassachusettsMedicalCenter,MassachusettsBiotechnologyCouncil,Massachusetts DepartmentofPublicHealth.

59b. Haseltine, William A. Prospects for Medical Control of the AIDS Epidemic. In: Daedalus: Living with AIDS, Part II. Published by Journal of the American Academy of Arts andSciences. 1989. 118:1-21.

60b. Haseltine,WilliamA. MolecularBiologyofHIV-1. In:AIDSandNewViruses. PublishedbyAcademicPress. 1989.

61b. TerwilligerEF,HaseltineWA. RegulationofReplicationofHIV-1. 1989.

62b. TerwilligerEF,SodroskiJG,HaseltineWA. MechanismsofInfectivityandReplicationof HIV-1andImplicationsforTherapy. AnnalsofEmergencyMedicine. 1989. 19:233-241.

31

63b. Haseltine,WA. DevelopmentofAntiviralDrugsfortheTreatmentsofAIDS:Strategies& Prospects.JournalofAcquiredDeficiencySyndromes.1989.2:311.

64b. HaseltineWA. TheGeneticCode. In: Microverse. Eds.: PreissB,Alschuler,W 1990.

65b. HaseltineWA,FarnetC,GottlingerH,LanghoffE,andTerwilligerE. StudiesofHIV-1 replication. Theroleofp6,integration,andgrowthinperipheralblooddendritic cells.RetrovirusesofHumanA.I.D.S.andRelatedAnimalDiseases. Cinquieme ColloqueDes CentGardes. 1990.201-212.

66b. FineHA,HaseltineWA. RNATumorViruses.In: CancerMedicineTextbook. Eds.: Frei E.1991.(InPress).

67b. HaseltineWA. AIDS.In: Americana. Ed: GrolierInc. 1991. (InPress).

68b. HaseltineWA. HIVResearchandnefAlleles. Science. 1991.

69b. HaseltineWA. TheMolecularBiologyoftheHumanImmunodeficiencyVirusType 1. 1991. FASEB. 2349-2360

70b. HaseltineWA. HumanImmunodeficiencyVirus(HIV)GeneExpressionandFunction. In: TheHumanRetroviruses. Ed: AcademicPress. 1991. 69-106.

71b. HaseltineWA. MolecularBiologyoftheAIDSVirus: TenYearsofDiscovery-Hopefor theFuture. In: ScienceChallengingAIDS. Ed:Karger 1992. 71-106

72b. Haseltine WA. Managing the Socio-Economic Implications of Genetic Engineering. In: Leadership and Management in the Information Age. The Emirates Center for Strategic StudiesandResearch.2002.132-160.

Publications Edited

1d. Haseltine,WA. RegulationofHIV-1Replicationbytatandrev. In: GeneticStructureand RegulationofHIV-1. Eds.:HaseltineWA,Wong-StaalF. RavenPress. 1991. 1-42.

2d. Kalland, KH, Langhoff EL, BosHJ,GottlingerH,andHaseltineWA. Retroviralregulatory proteins and the nucleolus. In:GeneticStructureandRegulationofHIV-1. Eds.:HaseltineWA, Wong-StaalF. RavenPress. 1991. 377-390.

3d. LanghoffEL,TerwilligerE,KallandKH,PoznanskyM,BosHJ,BaconO,SodroskiJ,And Haseltine WA. HIV-1infectionofhumandendriticcells. In: GeneticStructureandRegulation ofHIV-1. Eds.: HaseltineWA,Wong-StaalF. RavenPress. 1991. 511-525.

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4d. LuY,HeyA,TouzjianN,StenzelM,andHaseltineWA. CellularTranscriptionFactors whichRegulateHIV-1Replication. In: GeneticStructureandRegulationofHIV1. Eds.: HaseltineWA,Wong-StaalF RavenPress. 1991. 415-435

5d. HellandD,RepkeH,CaputoA,andHaseltineWA. TheExogenousTransactivation ActivityofHIV-1tat. In: GeneticStructureandRegulationofHIV-1. Eds.: HaseltineWA, Wong-Staal. RavenPress.1991. 301-310

6d. Terwilliger EF, Langhoff E, and Haseltine WA. The nef Gene of HIV-1 A Review of Recent Results. In: Genetic Structure and Regulation of HIV-1. Eds.: Haseltine WA, WongStaalF. RavenPress.1991. 457-471.

7d. CohenEA,TerwilligerE,andHaseltineWA. ThevprProteinofHIV-1isaVirionAssociatedPositiveRegulatoryProtein. In: GeneticStructureandRegulationofHIV1. Eds: HaseltineWA,Wong-StaalF RavenPress.1991. 451-456

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