3 minute read
Exosomes: The Cutting-Edge Secret to Hair Restoration and Beyond
from The Link Issue 51
by The AHLC
By Jeremy Wetzel, MD, Anderson Center for Hair, Atlanta, GA
In the world of regenerative medicine and aesthetics, a ground-breaking innovation is capturing the spotlight: exosomes. These microscopic messengers, also known as extracellular vesicles, are transforming how we approach tissue healing, anti-aging treatments, and even hair restoration.
So, what exactly are exosomes?
Think of them as tiny communication hubs produced by various cells throughout the body. They function as carriers of vital information, delivering a cargo of growth factors that can instruct other cells on how to behave. When it comes to hair restoration, these exosomes can send a powerful message to hair follicles, prompting them to grow healthier and thicker hair.
One of the most exciting uses of exosomes in regenerative medicine is in treating hair loss. Derived from the stem cells of umbilical cord blood, one of the most potent sources of regenerative cells, these exosomes are designed to foster growth and rejuvenation. When introduced into areas affected by hair loss, they can reduce inflammation, stimulate new blood vessel formation, and even counteract the miniaturization of hair follicles. Essentially anyone is a candidate for exosome therapy, but it is particularly useful for individuals with diffuse thinning or those not suited for surgical treatments. They can also be used in conjunction with a hair transplant procedure, similar to the way we use platelet-rich plasma (PRP) to enhance the growth of the transplanted follicles. Finally, because of their ability to decrease inflammation, they can be a good adjunct in the treatment of scarring alopecias.
The procedure itself is relatively straightforward. Typically involving only minor discomfort and lasting about an hour, exosome injections allow patients to return to their daily routines almost immediately. Results usually start to become noticeable within three to six months. While not everyone may see dramatic hair regrowth, most patients benefit from reduced hair shedding and a slowed progression of hair loss. Exosomes treatment is usually combined with other hair loss prevention strategies for optimal results; ongoing treatments such as medication and lowlevel laser therapy are recommended in conjunction with an exosomes procedure. Generally, we are recommending this as a one-time treatment, although boosters may be indicated in certain cases. This differs slightly from other regenerative medicine techniques such as plateletrich plasma (PRP) where treatments are needed at more regular intervals, such as every three months. The typical follow up after treatment is every three months for one year to track progress.
What is more, exosomes are well-tolerated by the body since they are not living cells and thus pose no risk of rejection. In our experience, they are considered safe, with no adverse effects reported.
In summary, exosomes are paving the way for innovative solutions in hair restoration and beyond, offering a glimpse into a future where regenerative medicine might be more effective and accessible than ever before.
