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Innovative calcium product solutions to maintain better health DestabTM directly compressible calcium carbonate supports the development of sachets, tablet compression, and capsules with high palatability and exceptional bioavailability Calcium is the most common mineral found in the body and is an essential key mineral supporting overall bodily health and functionalities. Particle Dynamics supports emerging calcium product needs that helps manage calcium deficiencies. According to Medical News Today (Newman, 2020), calcium plays an integral role in the human body as calcium helps: • Build bone health by boosting bone density • Support strong teeth • Regulate muscle contractions: calcium works synergistically with the proteins in the muscle to aid in muscular contractions and relaxation • Maintain cardiovascular health: calcium helps maintain the heart muscle functionality • Lowering blood pressure - linked to high calcium consumption • Improve cholesterol levels • Lower the risk in colorectal adenomas • Manage acid reflux • Prevent calcium deficiency health problems
Calcium product offerings by Particle Dynamics Particle Dynamics explores new approaches to great tasting tablets and capsules using flavoured ingredients and Destab™ direct compressed ingredients. Particle Dynamics’ Destab™ direct compressed Calcium Carbonate supports the development of sachets, tablet compression, and capsules. Complete packaging, stability and regulated documents support the efficacy of Particle Dynamics’ calcium product lines coupled with Drug Master Files for various product lines. Destab™ is an innovative direct compressible excipient from precipitated calcium carbonate offering exceptional bioavailability with improved swallowability comprising grades that provide superior mouth feel for an ultimate organoleptic experience and more. Utilising the full benefits of Destab™ Calcium Carbonate 95/90 HD Destab™ Calcium Carbonate 95/90 HD offers an advantage as its high density (HD) affords high loading elemental calcium ions into capsules. 6
Particle Dynamics Destab™ direct compression advantages • Superior compaction properties at low compression forces • Decreased friability concerns • Improved flowability • Uniform particles • Low dust • Improves content uniformity of tablets • Ensures accurate dose delivery • Bulk density increased • Improved surface tension • Improved porosity • Reduced wear of tooling dies - Increased tooling life - Increased compression ease (fluid & cohesive powder flow properties) - High speed tablet compression - increased throughput • Eliminates powder segregation • Improves tableting: strength + compressibility = compactability • Minimises lot to lot variances • Reduces quality control concerns
• Uniform tablet weights
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