HealthcareNews
Content 1 New binder for clean label tablet formulation
2 SEPIFILM™ White TF for pharmaceuticals
3 Chicory root fibres make you feel better
4 Jost introduces Magnesium Salts
5 SEPIBLISS™ - comfort and
soothing for modern skins
6 Supporting healthy sleep 7 Not just an active, an API 7 New Area Sales Manager to our Healthcare department
8 Get the most out of
Tocotrienols with Davoslife E3 Bio-Enhanced 20
9 Xylitol and erythritol for direct compression
9 100% pure Magnesium Glycinate
10 Fully reacted mineral salts 11 Want appealing coatings?
01/19
New binder for clean label tablet formulation Ribus releases Nu-BIND as an alternative to synthetic and plasticised binders RIBUS Inc. internationally launched its latest clean label excipient for tablets, Nu-BIND, at Vitafoods in Geneva. NuBIND is RIBUS’ sixth product launched as part of its clean label portfolio. RIBUS ingredients work as alternatives and functional solutions for conventional and certified organic products to improve production efficiencies and allow for clean label declarations.
Natural alternative to synthetic and plasticised binders
make-up of Nu-BIND includes guar gum, gum arabic, agave fiber, rice hulls and agave syrup to work as a binder. Nu-BIND will take the place of these synthetic ingredients previously considered vital in making dietary supplements: Hydroxy-PropylCellulose (HPC), Polyvinyl-Pyrrolidone (PVP), Hydroxypropyl Methylcellulose (HPMC), Polyethylene Glycol (PEG), pregelatinised starch and gelatin. NuBIND is available as a conventional or organic ingredient.
Nu-BIND is designed to act as a natural alternative to synthetic and plasticised binders, making the production of certified organic tablets possible. Nu-BIND will remove a major hurdle facing many natural and organic supplement companies wishing to make “clean label claims” and enable the $1.2 billion organic supplement industry to expand even further. The
“Excipients have become the primary barriers for companies with supplements seeking clean labels for both organic and conventional products,” said Steve Peirce, president of RIBUS. “We are thrilled to launch Nu-BIND as a clean label binding solution for conventional or certified organic tablet production. It is a critical ... >>
HealthcareNews 1/19
SEPIFILM White TF for pharmaceuticals Seppic’s alternative to TiO2 white coatings is now available for pharmaceutical applications SEPIFILM™ White TF is now available for the pharmaceutical market.
oxide, and without compromising the quality:
In order to meet customers’ emerging needs, Seppic has made sure that SEPIFILM™ White TF is provided with all the regulatory and technical information necessary for the pharmaceutical market.
xx ready-to-use
SEPIFILM™ White TF is a white coating agent made without titanium di-
xx efficiently covering the tablet core
>> addition to our robust clean label
portfolio for companies who are seeking clean label alternatives in the production process.”
Ribus’ organic line Nu-BIND is the latest ingredient to join RIBUS’ certified organic product line allowing for a clean label declaration including: xx Nu-MAG, a binder and alternative to magnesium stearate. xx Nu-Flow, an alternative to anticaking agents including silicon dioxide, tri-calcium phosphate or talc. xx Nu-RICE, a patented hypoallergenic extract from rice bran that serves as a hydration aid.
xx easily andled with classical coating parameters xx ensuring a white colour and strong opacifying properties
xx Nu-BAKE, a patented hypoallergenic and gluten-free extract from rice bran that delivers multiple functionalities to improve baking products. xx Nu-FLAC, a plating substrate for flavours and colours. Companies around the world know RIBUS as the original clean label ingredient company that supplies natural and organic rice-based ingredients. RIBUS produces non-GMO, natural, organic, vegan and gluten-free ingredients for the food, beverage, pet and dietary supplement sectors. Its patented technology and ingredients are designed to help solve production issues while bringing innovation and clean labels to a wide variety of products. 2
SEPIFILM™ White TF is EXCiPACT™ certified – all components are EP, USP-NF and JP compliant. Suitable for pharma and nutra applications 3-5 % weight gain 12 % solid content in dispersion Based on HPMC
“Regulations and global consumer demands have fuelled actions resulting in manufacturers around the world reformulating or creating new clean label products,” said Peirce. “We are helping companies make their organic and non-GMO claims a reality, while fixing a major barrier to getting cleaner products on the market and to consumers.” Contact Alsiano for more information about Nu-BIND and other RIBUS ingredients.
HealthcareNews 1/19
Chicory root fibres make you feel better Consumers are increasingly interested in the role that nutrition can play not only in their physical but also in their emotional well-being. Fibre up for an improved quality of life! There is a growing interest in the effect that the gut microbiome has on our feeling of wellbeing. Roughly 7 in 10 believe it plays an important role in overall physical health. What’s more, 3 in 5 believe it impacts also their mood and daily energy levels1.
The gut is where the magic happens The digestive tract plays a crucial role for health and well-being. In the past, researchers, medical doctors and nutritionists/dietitians focused on the activities in the upper part of the intestine, the so-called small intestine, where digestion and absorption take place. The lower end of the intestine is the colon, also called the large
Chicory root fibres are the only proven plant-based prebiotics intestine. For a long time it was just seen as the place where food residues are concentrated for final excretion as faeces. Today, it is an organ of super importance for health and well-being.
Several essential functions with outreach to metabolism and other organs in the body are situated in the colon.
The link between digestive health and inner well-being with chicory root fibres It has become obvious that the colon has a key role to play for overall and long-term health as well as inner wellbeing. Prebiotics are a unique tool to positively influence this organ and support its function by small dietary interventions. As of today, inulin and oligofructose (chicory root fibre) are the only clinically proven plant-based prebiotics. More than 30 human intervention studies are demonstrating the increase in bifidobacteria after intake of inulin or oligofructose from chicory roots. Enrichment of foods and drinks with these fibres is easy to apply and very tasty. A review of the science of prebiotics is laid down in a consensus statement developed by the International Scientific Association for Probiotic and Prebiotics (ISAPP) in 20172 and in a meta-analysis prepared by So et al. 3
20183. Chicory root fibres support the colon’s health by increasing beneficial bacteria contributing to improved bowel regularity. The production of short-chain fatty acids upon prebiotic fermentation of chicory root fibres stimulates reflexes which make the bowel contents move. Furthermore, the increase in bifidobacteria means a higher bacterial biomass leading to more faecal bulk. In addition, stool softening occurs as more water stays in the colon instead of being re-absorbed. All this exerts an effect on stool frequency and/or stool consistency supporting overall bowel regularity within the normal range. These scientifically demonstrated improvements in regularity go hand in hand with an overall “feel-good” perception, measured scientifically by designated questionnaires addressing quality of life.
Improved inner well-being and digestive health with chicory root fibres Improved regularity is obviously linked with a higher quality of life: people feel better. A deeper dive into this was done by Vandeputte et al.4 >>
HealthcareNews 1/19
>>
1. Statistics prove the correlation between specific parameters Statisticians found a direct correlation between microbiota effects, stool characteristics and inner well-being. A correlation was found between lower amounts of the potentially harmful Bilophila bacterium and better satisfaction. Further, the scientists saw that lower amounts of Bilophila correlated with softer stools. This proves that chicory root fibre intake and aspects of digestive health and inner well-being are linked4.
2. How daily intake of chicory root fibre improves digestive health and inner well-being Achieving such inner happiness and feeling of well-being seems magic – but it isn’t, it is as simple as 1-2-3. By including small portions of Orafti® prebiotic fibres into your daily diet, you can already realise an effect.
These increased fibre levels reach the gut and will allow its microorganisms to flourish and contribute to improved bowel regularity. The achievement of such inner well-being is a unique one – individual and with its own fibre balance. A change of the daily diet is not a drastic one. For example, with a few grams of chicory root fibre in the morning bowl of cereal and another few in a mid-morning snack (like yoghurt or some cookies), one could already achieve the desired effect by lunchtime. Building this into your nutritional routine to achieve the personal fibre balance can make a world of difference! Would you like to know more? Please contact us for the full version of Beneo’s paper on nutritional insights into inner wellbeing and quality of life.
References and study design dictionary 1. HFI Health Focus International Global Trend Study 2018 2. Gibson GR, Hutkins R, Sanders ME, Prescott SL, Reimer RA, Salminen SJ, Scott K, Stanton C, Swanson KS, Cani PD, Verbeke K, Reid G (2017) Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol 14(8):491–502. http://www.nature.com/articles/nrgastro.2017.75 3. So D, Whelan K, Rossi M, Morrison M, Holtmann G, Kelly JT, Shanahan ER, Staudacher HM, Campbell KL (2018) Dietary fiber intervention on gut microbiota composition in healthy adults: A systematic review and meta-analysis. Am J Clin Nutr 107(6):965– 983. https://www.ncbi.nlm.nih.gov/pubmed/29757343 4. Vandeputte D, Falony G, Vieira-Silva S et al. (2017) Prebiotic inulin-type fructans induce specific changes in the human gut microbiota. Gut 66(11): 1968–1974. http://gut. bmj.com/content/gutjnl/66/11/1968.full.pdf
O
Jost introduces Magnesium Salts Jost Chemical Co. is now manufacturing Magnesium Aspartate Dibasic Anhydrous and Magnesium Citrate Tribasic Anhydrous. Both products are manufactured under systems that comply with cGMPs. These products are typically used in pharmaceutical, nutritional and cosmetic applications. Magnesium Aspartate Dibasic has an As-Is magnesium content of 14.2–
15.7 %. Magnesium Citrate Tribasic offers a slightly higher As-Is magnesium content of 14.5 – 16.4 %.
Magnesium Aspartate Dibasic
O Mg2+
-
O
O-
NH2 O-
Magnesium Citrate Tribasic Anhydrous
3 Mg2+ O-
Jost Chemical Code Formula
Product name
2520 Mg(C4H5NO4) Magnesium Aspartate Dibasic Anhydrous 2549 Mg3(C6H5O7)2 Magnesium Citrate Tribasic Anhydrous USP
4
O
O-
OH O
O
HealthcareNews 1/19
SEPIBLISS™ - comfort and soothing for modern skins The first nutricosmetic ingredient dedicated to sensitive and reactive skins - neuro-soothing, anti-inflammatory, protective actions Skin reactivity - a complex, global and growing concern Skin sensitivity is usually defined by unpleasant sensations in response to aggressions that normally should not provoke such reactions. Itching, tingling, redness, irritation are various manifestations. These reactions can be induced by many external stressors (UV exposure, dry heat, extreme weather conditions, pollution, smoking, poor food habits and alcohol consumption) but also by internal factors (hormonal change, emotional stress or alteration of the barrier function of the skin). It could be a temporary or long term condition and it is observed on different parts of the body such as the face, hands, and legs. Today, 50% of the population is concerned by sensitive skin. It is important to address the challenge of this specific skin condition.
Quest for natural and efficient solutions Consumers are always looking for more efficient and convenient solutions to take care of their skin. Nutritional solutions offer a deep, global
and long term action in just a simple gesture, and are easy to take on-thego or at home. Also, consumers are paying more and more attention to labels and origin of products. This can be considered even truer for a person with sensitive skin, as skin reactivity undoubtedly drives awareness toward natural and additive free products.
SEPIBLISS™ - active science inspired by nature SEPIBLISS is a virgin coriander seed oil, which is locally produced in the south-west of France, and its manufacturing process does not involve any solvent. It contains no additives and is suitable for vegetarian, kosher and halal diets.
Comprehensive approach to soothe sensitive skin SEPIBLISS™ has been developed to offer a comprehensive soothing effect for sensitive skin: reducing skin reactivity to skin stressors via a neurosoothing action and an anti-inflammatory action, and better protecting the skin against aggressions, via an antioxidant action and a barrier reinforcing action. 5
Its skin soothing and anti-inflammatory activities have been demonstrated with in vitro models on human keratinocytes and human keratinocytes-neurons co-culture.
Skin benefits SEPIBLISS™ offers three skin benefits to consumers: xx Fighting and resisting a wide range of aggressions like UV, pollution, and stress. xx Comforting and soothing sensitive, reactive and atopic prone skins. xx Reducing unpleasant reactions: itching, tingling, irritation, blushing, etc. SEPIBLISS™ offers opportunities to develop formula dedicated to soothing and reducing symptoms of skin reactivity or more classic nutricosmetics formula (hydration, anti-aging, UV, glowing) that are specific for sensitive skin. • 100% virgin coriander seed oil • Designed for food supplements • Dedicated to sensitive and reactive skins • Science driven (in vitro data)
HealthcareNews 1/19
Supporting healthy sleep A good sleep is essential for a healthy body and soul. There is good help to be found in nature where over the years different botanicals have been used to support sleep Sleep problems threaten the health and quality of life of up to 45 % of the world’s population. The market for sleep aids has been increasing in recent years. This is due to a range of different factors such as stressful modern lifestyles, population ageing and increasing awareness of sleep disorders.
Lemon balm Lemon balm (Melissa officinalis) is a herbaceous plant native to the Mediterranean. It has been reported to have calming effects and is used to reduce anxiety, sleep problems and restlessness.
Linden
Frutarom offers a wide range of botanical extracts which can be used to support sleep:
Linden (Tilia cordata) is a species of tree and bush native to Europe and Western Asia. It has traditionally been used to help mild insomnia and anxiety.
Chamomile
Passion flower
Chamomile (Chamomilla recutita) is commonly regarded as a mild tranquiliser or sleep inducer. Its calming effect may be attributed to an antioxidant called apigenin, which it contains in abundance. Apigenin binds to specific receptors in the brain that may decrease anxiety and initiate sleep.
Passion flower (Passiflora incarnate) is a common component of herbal sleep aid formulations. It has long
Hops Like valerian, hops (Humulus lupulus) have a long history of being used to help improve sleep. Scientific research shows that their natural sedative effects can increase sleep duration. In addition, hops help lower body temperature (falling core body temperature is an important physiological step towards sleep). 6
been used by American Indians for its sedative and anxiolytic effects and is approved by the German Commission E to treat nervousness and insomnia.
Valerian Valerian (Valeriana officinalis) is the best known natural tranquiliser, sleep aid and stress reducer in Western herbal medicine. Recent studies reveal a specific binding site on neuronal receptors as the fundamental target through which valerenic acid exerts its anxiolytic effect. Please contact us for more information about Frutarom’s natural solutions for supporting sleep.
HealthcareNews 1/19
Not just an active, an API TECA Pharma’s regenerative properties can be applied to many applications In 1958, the first medicine based on TECA™ Pharma obtained its marketing authorisation, demonstrating the efficacy, safety and quality of this API. Since then, several medicines have been launched with this API of which applications include: Topical use: healing of wounds, burns, ulcers, scar treatment and prevention of scar tissue. Oral use: symptoms alleviation and prevention in chronic venous insufficiency and diabetic microangiopathy.
New developments The regenerative properties of TECA™ Pharma can be applied to a whole range of new applications,
where it can bring a real benefit to patients: xx Acne scar healing
60 years of efficacy & safety in pharmaceutical applications:
xx Mucosae applications: hemorrhoids, after vaginal infection, buccal/ gingival lesions …
• Topical use: wound healing, burns, ulcers, scars
xx Any situation where a disease or a treatment brings cutaneous / mucosal damages.
• For pharmaceutical & medical device development
TECA™ Pharma has a potential in relation to many unmet needs, one such example being the diabetic foot ulcer. Asiaticoside, a major constituent of TECA™ Pharma, has been shown to facilitate diabetic wound healing. Several candidates based on Centella asiatica are now being evaluated for such conditions.
• Oral use: venous insufficiency
A reliable active TECA™ Pharma is a highly purified extract manufactured under a GMPcertified process. An ASMF (Active Substance Master File) is deposited in several European countries to facilitate the regulatory filing of customers.
New Area Sales Manager to our Healthcare department We are pleased to announce that as of 1 April 2019 Peter H. Bendtsen has joined Alsiano as Area Sales Manager.
vinced that his knowledge will contribute significantly to our team and to Alsiano.
Peter has more than 20 years of experience in commercial sales to different industries within the chemical sector. We are very excited that Peter has chosen to join us and we are con-
Peter will be based in Denmark where he will be working with the Personal Care, Health & Nutrition and Beverage industries.
7
HealthcareNews 1/19
Get the most out of Tocotrienols with Davoslife E3 Bio-Enhanced 20 Patented self-emulsifying vitamin delivery system with a complete spectrum of Tocotrienols and high bioavailability DavosLife E3 Bio-Enhanced 20 is a patented self-emulsifying vitamin delivery system. This formulation contains the complete spectrum of Tocotrienols with α-Tocopherol and offers 46% higher bioavailability compared to a market sample. A higher bioavailability leads to a higher concentration of Vitamin E in the body, maximising the benefits of neutralising free radicals and reducing chronic inflammation. Tocotrienols are up to 60 times stronger in antioxidant activity compared to α-Tocopherol with unique anti-inflammatory properties.
Clinically proven enhanced absorption Davos Life Science commissioned an opened-label, randomised, 4-way
cross-over clinical study to compare the bioavailability of DavosLife E3 Bio-Enhanced 20 with a market sample. This study was conducted on 28 healthy volunteers with a dosage of 200 mg Tocotrienols. DavosLife E3 BioEnhanced 20 delivers a higher concentration of Tocotrienols (Cmax) to plasma compared to the market sample at the same time point (Figure 1). The Area Under the Curve (AUC) of Figure 1 represents the overall exposure of the body to Tocotrienols over time. DavosLife E3 Bio-Enhanced 20 has a greater AUC compared to the market sample and therefore the higher bioavailability between the two (Figure 2). Figure 2
Plasma total tocotrienols
More individual isomers delivered to plasma Higher concentrations of each individual Tocotrienols isomer is delivered to plasma compared to the market sample (Figure 3). Figure 3
Figure 1
8
HealthcareNews 1/19
Xylitol and erythritol for direct compression Alsiano offers erythritol and xylitol contributing effective compaction properties within specific tableting applications and usages Alsiano offers direct compression versions (DC) of erythritol and xylitol to the tableting industries for filling or binding applications. Both products are sugar free low calorie bulk sweeteners containing exceptional sweetness and providing flavour improvement. DC production methodology requires excipients of a high quality and functionality. Xylitol and erythritol can contribute where simple tableting
applications are required. They are now increasingly used and principally adapted to direct compression applications for high-quality chewable lozenges or tablets, with a pleasant taste and texture.
Low and almost zero calorie Erythritol and xylitol can offer tableting processors potential to utilise a low kcal product and almost zero kcal too if erythritol is chosen. Our products can provide the desired texture,
• Pleasant taste • Smooth mouthfeel and texture • Low or almost zero calorie • Cooling effect • Tooth-friendly appearance and dosage combined with mouthfeel and sweetness flavour which are key components of various formulations.
100% pure Magnesium Glycinate Jost now offers 100% pure, fully reacted magnesium glycinate. The high purity Magnesium Glycinate Purified Powder from Jost is low in heavy metals: xx xx xx xx
mercury < 1 ppm lead < .3 ppm arsenic < 1 ppm cadmium < .5 ppm
Magnesium glycinate is just one of Jost’s high purity magnesium salts which are lot-to-lot consistent, and have extremely low levels of lead, arsenic, cadmium, and mercury. With over 30 years of experience, Jost manufactures high purity in cGMP compliant, FDA-registered facilities. All products are fully reacted, consistent from lot-to-lot and meet all customer requirements. 9
Magnesium glycinate, which is magnesium bound to glycine, is often used for magnesium deficiency. It has been reported that magnesium glycinate has very good absorption levels and is also one of the gentlest supplements on the stomach. According to research published by the American Physiology Society, magnesium supplements have been shown to help with migraines, anxiety, chronic pain, heart disease, and diabetes.
HealthcareNews 1/19
Fully reacted mineral salts The use of mineral salts containing unreacted compounds can lead to formulation stability problems and inaccurate ingredient declarations on the finished product The emphasis on health and nutrition has focused attention on mineral supplements. With the market for mineral supplements continuing to grow and becoming more sophisticated, the need for good chemistry at the point of production becomes more apparent. In October 1994, the U.S. Congress passed the Dietary Supplement Health and Education Act (DSHEA). DSHEA called for the establishment of current Good Manufacturing Practices (cGMPs) for dietary supplements. The FDA notice of proposed rule making for dietary cGMPs was first published in 1997, and has yet to be finalised. The lack of published monographs on many widely used mineral salts and instances of non-compliance with established monographs reinforce the need for good chemistry and accurate content disclosure. This regulatory ambiguity is a cause of concern for supplement manufacturers leaving them wondering: Are the products I buy safe for their intended use? Are the products fully reacted? Do the chemical manufacturing processes produce the desired product? The process for manufacturing fully reacted pure salts involves the reaction of an acid and a base in an aque-
ous solution and the precipitation of a salt compound.
Negative ramifications of an incomplete reaction
Dissolving the reactants provides the opportunity for a complete reaction to occur. This stands in contrast to a dry blend of an acid and a base. In blended or partially reacted products, the mixing of the acid and base might be complete but the reaction might not proceed to completion because of lack of opportunity. The lack of dissolution inhibits solvation of the reactants and leads to a slower and ultimately a less complete reaction.
Unlike a fully-reacted salt, the blend might be unstable over time because of a slow but on-going reaction, as the alkaline minerals react with any acidic ingredients in the formula. This instability can cause the blend to harden over time or tablets to disintegrate. A blended product might be low or high in pH because of an imbalance in the acid-base stoichiometry. The pH imbalance can lead to problems with the product integrity. Structure and content uniformity can suffer if the product contains a mineral blend and not the fully reacted salt. In compounding operations, blends can separate based on differing physical characteristics. >>
Most fully reacted salts have a fairly neutral pH Blended products might exhibit an acidic or alkaline pH. Infrared spectroscopy, nuclear magnetic resonance spectroscopy, thermal gravimetric analysis and numerous other techniques can be used to differentiate between a fully reacted mineral salt and a blend of reactants. Depending upon the mineral salt, the addition of acid to the sample can demonstrate the presence of unreacted mineral base. If carbonate is present, effervescence will occur. In the case of hydrated Magnesium Citrate Tribasic, a material not fully reacted when put in water will cause a reaction and temperature increase. 10
Jost Chemical Co. is a manufacturer of fully reacted, pure mineral salts that meet USP/EP/FCC monographs, if applicable. Jost follows the science of manufacturing only pure materials that are the true chemical entity and not a blend or mixture of components.
HealthcareNews 1/19
Want appealing coatings? Try clean label rice starch! Coating with rice starch enables smooth and white tablets with a clean label All natural, no additives, no preservatives, organic - all the right buzz words to catch consumers’ attention. Over the last decade, there has been a noticeable rise in product launches with a cleaner and transparent label and the worldwide market pull shows no sign of abating. BENEO regular rice starch, Remy B7, contributes to a high level of whiteness in tablet coatings. This makes it a natural choice for colour coatings with a cleaner label. Thanks to its very small granule size, BENEO rice starch can also easily smoothen rough sur-
>> Another negative ramification occurs
when the blend is exposed to water. Processes such as wet granulation or adding the blend into a consumer’s drink might allow a reaction to occur at an inopportune time, thereby damaging the integrity of the final product. These deficiencies are not typically found when using fully reacted mineral salts. Besides an end product that may be unstable, formulations that contain blended mineral ingredients may have a misstated ingredient label as well. An example would be a magnesium
faces of the tablet during the coating process.
Beneo offers a clean label solution with Remy B7 Remy B7 native rice starch has a very fine granule size (2-8 micron) and a smooth granule surface giving it a smoothening effect. The starch shows very good adhesion properties and is imperceptible in the mouth. Coating with Remy B7 results in natural white end product thanks to the ingredient’s natural whitening effect. On the product label, it is simply declared as “(rice) starch” (= clean label).
citrate that lists magnesium content at 20%. This magnesium level is not possible based upon the stoichiometry of a fully reacted salt. As stated in the USP monograph, Magnesium Citrate Tribasic can only offer 11.2 – 12.0 % magnesium on the “As-Is” basis in the hydrated form. Jost Chemical has the drying capability to offer an anhydrous product, whose theoretical magnesium content range is 14.5 – 16.4%. But with the available drying capabilities in today’s manufacturing environment, a magnesium content level above 15.5 % is rarely achieved. It is 11
What are the benefits of coating with Remy B7? • Smooth and white tablet coatings. • A clean label ingredient solution • Reduction of drying time during the coating process, increasing production capacity. • No impact on sensorial properties of the final product.
apparent that products claiming higher magnesium content are blends. Appropriate labeling should list the ingredients comprising a “blend” such as magnesium citrate and magnesium oxide, so that the finished product complies with the FDA ingredient declaration mandates.
HealthcareNews 1/19
Alsiano Food & Healthcare Team
Anders Hager
Anna Carin Djerf
Bente Mørkøv Ølgaard
Charlotte Dahl
Sales assistant, Food E: bm@alsiano.com T: +45 8230 0001
Sales & logistics coordinator, HC E: cd@alsiano.com T: +45 8230 0051
Diana Dosen-Grunning
Hedvig Åkesson
Kristian Hansen
Lena Molin
Managing Director E: ahg@alsiano.com T: +45 8230 0026 M:+45 2618 8545
Area sales manager, Food E: ddg@alsiano.com T: +46 707 333 343
Sales ssistant, Food E: acd@alsiano.com T: +46 722 148 083
Area sales manager, HC On maternity leave
Lene Aarøe Nissen
Malene Rask Harder
Monica Kindberg
Peter H. Bendtsen
Business manager, HC E: lan@alsiano.com T: +45 8230 0025 M:+45 2270 1002
Business manager, Food E: mk@alsiano.com M:+45 2046 4121
Sales manager, Food E: kh@alsiano.com T: +45 8230 0012 M:+45 2270 1003
Signe Mørck
Susse Liff Hansen
Area sales manager, Food E: mt@alsiano.com T: +45 8230 0016 M:+45 4073 8441
QA manager E: slh@alsiano.com T: +45 8230 0017 M:+45 4071 8338
Circulation: 400 copies
Editor-in-chief: Lene Aarøe Nissen
Tina Johansson
Michael Telsing
Sales assistant, HC E: sm@alsiano.com T: +45 8230 0042
Area sales manager, HC E: phb@alsiano.com M:+45 2270 1015
Publisher: Alsiano A/S
Michael Brehmer
Area sales manager, Food E: mbr@alsiano.com M:+46 723 896 011
Sales assistant, HC E: mrh@alsiano.com T: +45 8230 0007
Area sales manager, HC E: lm@alsiano.com M:+46 722 048 245
Coordinator, text, layout: Dorthe Andersson
HealthcareNews is published 1-2 times a year and distributed to customer and other interested parties. Reproduction of articles appearing in HealthcareNews requires prior consent form the author. Alsiano is not responsible for the content of articles written by external authors.
Sales assistant, Food E: tj@alsiano.com T: +45 8230 0024
12