how do antioxidants work, antioxidants and free radicals naturevitaminsa.blogspot.com/2019/10/how-do-antioxidants-work.html
How do antioxidants work and what mean antioxidant and free radicals Antioxidants and free radicals Antioxidants are a molecule or coupled electron stable molecule. It stabilizes other molecules called free radicals by giving them electrons. antioxidants act as a free radical scavenger, electron and hydrogen donor, enzyme inhibitor. antioxidants have the potential to neutralize the harmful free radicals by donating e- and helps to reduce its capacity to cell damage.
some antioxidants are produced through normal body metabolism in the body including glutathione, ubiquinol, and uric acid. most of the antioxidants are found in foods such as: anthocyanine: blueberries, eggplant, grapes lutein: green leafy vegetables like spinach, broccoli tomatoes contain lycopene antioxidant lycopene: tomatoes, watermelon beta-carotene: apricots, spinach, and carrot cryptoxanthins: mangoes, pumpkins, and red capsicum
Many vitamins also act as antioxidants like vitamin E, C and vitamin A(beta-carotene). our body can't manufacture these vitamins. so, you should take it from the diet.
free radicals are a highly unstable and reactive molecule. they attack biologically active molecules such as DNA, protein, carbohydrate, and lipids causing cell damage and homeostatic disruption. There are many oxygen-free radicals such as nitric oxide radicals, oxygen singlet, and hypochlorite that are responsible for many diseases. All the micromolecules and 1/4
macromolecules are a target of free-radicals, but most of them lipid, protein, and nucleic acid are the major target. free radicals are generated through the essential metabolic process in the human body. some internally generated sources of free radicals are inflammation, peroxisomes, arachidonate pathways, and xanthine oxidase. They are also generated through some external sources such as cigarette smoking, certain drugs, and pesticide, industrial chemicals, radiation, and ozone. Both enzymatic and non-enzymatic source also serves as a source of free radicals. Many diseases are the result of an attack of free radicals either on the genetic material or essential body molecules like protein, lipid. studies reveal that atherosclerosis occurs due to the reaction of free radicals involving diet-derived lipids in the arterial walls and serum to yield peroxides and other substances. these substances cause endothelial cell injury and affect the arterial walls. cancer occurrence is associated with chromosomal effects and oncogene activation due to the reaction of free radicals. Free radicals can, directly and indirectly, affect body health such as: produce inflammation damage fat within cells change bad LDL cholesterol into arterial clogging substance premature aging cause severe injury or cells heath in lungs decrease the activity and availability of the neurotransmitter damage protein, resulting in the loss of biological activity
Antioxidants benefits May help to reduce inflammation delay the aging process reduces the risk of disease such as arthritis, edema and leg swelling, neurological disorder, heart disease, cancer. protect the damaging of lipid, DNA, and protein from free radicals promote the blood flow to the heart promote skin health
Foods that are high in antioxidants vegetables spinach 2/4
artichokes kale beets red cabbage fruits jujube sea buckthorn berries blueberries prune raspberries legumes lentils soybeans kidney beans black beans chick beans
How do antioxidants work studies show, that free radicals are generated in the human body by both external and internal sources such as metabolism, pollution, radiation, cigarette, herbicide, and in addition, stress, lack of exercise and sleep. These free radicals begin to attack nearby healthy cells and in an attempt to replace their missing e- on the attacked molecule loses its e-, it becomes a free radical itself. these can cause a chain reaction to occur, resulting in disruption of million of nearby molecules. this chain reaction is known as oxidative stress.
oxidative is condition occurs when the critical balance between the free radicals and antioxidants in the body is not maintained. oxidative start to be leading cause of the inflammatory disease(arthritis), ischemic disease(stroke, heart disease), premature aging, a neurological disorder(muscular dystrophy, Alzheimer's and Parkinson's disease) and even an increase the susceptibility of cancer. you can see the result of oxidation in everyday environments such as rusting pieces of metals, fruits that expose the air.
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antioxidants help to improve this condition in two steps. first, is the chain breaking in which antioxidants donate e- to the free radicals present in the body. second, it involves the removals of ROS/reactive nitrogen species initiator. antioxidants also affect the biological system in another way such as co-antioxidants, metal ion chelation, and gene expression regulation.
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