MareLife News July 2012 by http://obm.no

Newsletter from Marelife • July • 2012 NASF PRE-CONFERENCE • March 6 • 2012

MEETING POINT

NASF2012(picture) was agreatsuccess andNASF2013 is inthemaking!

The MareLife News

TRACING THE RUNAWAYS TheMareLife flagship project: genetic fingerprint

Carl Seip Hanevold (left) and Øystein Lie (right) reinforce the activities of Marelife from the new headquarters in Oslo Innovation Center.

Foto: Gorm K. Gaare

MOVING AHEAD!

THE MARELIFE NEWS • JULY • 2012

chairperson

Marelife, the independent science-based marine innovation network, has reinforced its staff and put in operation R&D projects initiated by experienced working groups covering key areas in marine innovation. A strong and committed staff combined with highly experienced people in our Board and core working groups, provides Marelife with a solid foundation for moving forward, says Marelife executive manager Øystein Lie. He also extends his acknowledgements to the resigning Board members and Chair who helped developing the current MareLife platform and he welcomes onboard the new ones.

Extended staff

The staff now consists of Øystein Lie (Executive Manager), Carl Seip Hanevold (Cermaq) (Working Chairperson), Jon Aulie (The Norwegian Seafood Federation, Marine Ingredients), Paul J. Midtlyng (Aquamedic AS, Aquaculture disease control),Sytse Ybema (Sustainovate, Ocean Resources) and Erik Fedde Lopez, Fedde Consulting (Administrative matters)

Our five working groups.

Marelife has five working groups in the core areas fisheries, aquaculture, ingredients industry, commercialization and reputation. These working groups have been initiating our R&D projects and strategic efforts like the Havlandet Norge report and are chaired by the following people: Fisheries: Lars Olav Lie (Liegruppen AS), Aquaculture: Petter Arnesen (Marine Harvest ASA Ingredients Industry: Jon Aulie (MARING Forum, the Norwegian Seafood Federation, FHL) Commercialization: Knut Traaseth (Norwegian Venture capital Association) Reputation building: Geir Myrold (TraceTracker AS)

New board of directors

Marelife` s annual meeting May 25 elected Carl Seip Hanevold as new chairperson of the board. The board now consists of: * Carl Seip Hanevold (Cermaq), Chairperon * Live Haukvik Aker (Considium Consulting), deputy chairperon * Kjetil Jakobsen, University of Oslo * Odd Magne Rødseth, AquaGen * Dag Knappskog, MSD Animal Health * Ørjan Olsvik, University of Tromsø * Torstein Steine, Norwegian University of Life Sciences, UMB * Espen Rimstad, Norwegian School of Veterinary Science, NVH * Kristine Naterstad, Nofima * Jon Aulie, The Norwegian Seafood Federation (FHL) MARING

The Nomination Committee

The annual meeting reelected the Nomination Committee for another two years. The committee consists of: Sissel Rogne, CEO, The Norwegian Biotechnology Advisory Board (Committee chairperson) Director General Arne Benjaminsen, Ministry of fisheries and coastal affairs (FKD) Geir Andreassen, CEO, The Norwegian Seafood Federation (FHL)

Far-reaching network

Jacobsen

Marelife has grown its membership base from 17 founding members to currently 48 members (see the member list here: http://www.marelife.org/our-network/our-members.html) and has a strong international network. We are building an important and far-reaching network, on a national, Nordic and international level, and have several thousand contacts, says Marelife general manager Øystein Lie.

MOVING AHEAD - withreinforcedstaffandanew

THE MARELIFE NEWS • JULY • 2012

Searching for new marine knowlegde at NASF Day Zero.

NASF DAY ZERO – pavingthewayformarine cross talk

The owners of of the international seafood conference NASF AS and the organizers of NASF 2012 have big promises for the next event in March 2013. New themes, new venue and much more are on the agenda in the run-up. - Like all the prior innovation seminars since 2009, the NASF 2012 Preconference was again a new experimental concept although we knew by experience that mobilizing more commercial solution providers and the emerging biomarine sectors together with seafood, Academia and finance would be expected to enhance cross talk and make the arena more complete, said Øystein Lie in his welcome address. In spite of the very diverse structure of operators and delegates we managed to execute a vibrant discussion across disciplines and sectors since you helped us to upgrade our common challenges and opportunities: The master goal for the marine sector across all fields is “smart and sustainable business” and this can best be achieved by systemic approach and solutions which again is best pursued by strengthening cross sector cooperation. The success of any conference session is depending on a well coached discussion. Jostein Refsnes, chair MARING Forum, Norwegian Seafood Federation served this task in a most excellent way and Karl Almaas, CEO Sintef Fishery and aquaculture and Douke Faber, Dutch Fish Product Board co-chaired us safely through the session. - More delegates than ever came to NASF 2012. In fact we had an all-time high attendance with some 560 top-level delegates from

32 countries and close to 300 companies attending the conference. This was 18 % above the 2011 delegate number, states the conference founder Jørgen J. Lund in a communication to the conference delegates. Lund notes that the NASF event this year was in effect a 3-day event, starting March 6th with the well known Day Zero preconference BioMarine seminar, organized by the MareLife Association. As the largest special session, the preconference Day Zero (nicknamed "Day-Z") attracted around 170 delegates to the crowded seminar room at Radisson Blu Scandinavia in Oslo, March 6th. - We managed to get the key players from the solutions provider and the biomarine sector to set the agenda for marine innovation, says prof. Øystein Lie. It is the fourth year that he organizes this preseminar to the North Atlantic Seafood Forum. Petter Dragesund, head of corporate finance at Pareto Securties, says to Oslo Business Memo that Pareto as a part-owner of the NASF will work to attract even more international seafood companies to the meeting in the years to come. The special session "Pareto Seafood Finance and Investor Seminar" presented 17 companies. - For our customers this is a good opportunity to meet the companies and talk to the managment face-to-face, says Dragesund. At the pre-conference Day Zero 20 innovative cases from companies in the marine solution provider sector where presented out of which four cases were awarded. Link to program: http://issuu.com/businessmemo/docs/nasf_2012_day_zero/1 Link to the presentations: http://marelife.org/downloads/category/13-2012-nasfpresentations.html Link to innovative cases: http://marelife.org/north-atlanticseafood-forum/innovative-case-portfolio.html Link to photo collection: http://obm.photoshelter.com/galleryslideshow/G00000eDvaBBuswQ/?start=

THE MARELIFE NEWS - NEWSLETTER TO MARELIFE MEMBERS EDITOR-IN-CHIEF: Øystein Lie | oystein.lie@marelife.org PRODUCED BY: Oslo Business Memo | post@oslobusinessmemo.no

THE MARELIFE NEWS • JULY • 2012

MARELIFE - atruetriplehelix The main “modus operandi” of MareLife is to foster innovation through facilitating cross talk between the private sector, the public sector and the R&D entities (the triple helix). MareLife is receiving critical important grants from Research Council of Norway, Oslo Municipality, and Akershus County Council through the so called VRI program to support this way of advancing innovation in the marine sector. The triple helix is the macro framework tool employed. Within this framework and at a more concrete level MareLife is employing three sets of consecutive tools in this order: dialogue conferences, competence processes and pilot projects. The first is putting on the agenda and discussing major challenges and opportunities in the marine sector, the second is following up by carrying out analysis and inventories and defining goals and efforts to address the challenges (MareLife work groups in action) and the third one is preparing and rigging pilot projects as preludes to more extensive innovation projects. The important and prestigious DNA tracing project described in this Newsletter was conceived through the above flow of processes. In addition to this MareLife is involved in addressing several other topics like microalgae as a new resource, test bed for marine ingredients, fishery technology, vaccinology, aquagenomics, sea lice combating efforts and not least assisting moving R&D based concepts (innovative cases) with commercial potentials into new phases by rigging them and exposing them to industry players and capital. The finance and resource packaging of MareLife budget to undertake this massive work is constituted by the following sources: the VRI grants, the member fees, project and service incomes and not least and the major components: in kind contribution from the members involved.

OCEAN21 - shapingthemarinestrategy Ocean 21 is the Norwegian government's marine research strategy. Representatives from the industry, the administrative authorities and the community are invited to work on Ocean21. “The strategy shall be tasked to draw up guidelines as to how Norway should structure and manage the overall marine research effort,” Norway’s Minister for Fisheries and Coastal Affairs, Lisbeth Berg-Hansen, said when she launched the strategy initiative in 2011. The Ministry of Fisheries and Coastal Affairs formulated a mandate for the steering group and its composition, together with seven other involved ministries. The Research Council forms the secretariat for this work. An external steering group is established for Ocean21, with participants drawn from the industry, the administrative authorities and the community. The steering group is preparing a report including recommendations for all the eight ministries involved. Marelife is heavily involved with the strategy work in Ocean21 and especially through the network Storby Marin has positioned members and allies in both the strategy group, which leads the work of Ocean21, and in working groups. The four working groups (management, aquaculture, fisheries and food) are central to develop proposals for priorities in key subareas. The working groups comprised of experts from industry, research organizations and other relevant stakeholders as members. Professor Olaf Styrvold (University of Tromsø), CEO Alf Helge Aarskog (Marine Harvest), CEO Unni Steinsmo (SINTEF) and CEO Arne

Karlsen (The Norwegian Seafood Research Fund) are in the steering group. CEO Lars Olav Lie (Liegruppen) is a member of the working group for fisheries. Ocean21 shall deliver a research and development strategy (R & D) by the end of 2012.

MICROALGAE - meets theneedforlipids The marine industries has a series of grand challenges. Access to marine lipids is one of the most important tasks to be solved. The industries has comparatively low carbon foot print: Space and energy efficiency, low feed conversion ratio. But a series of grand challenges, one of which is to secure proteins for feed, and lipids, anti oxidants etc. in feed ingredients to the escalating aquaculture. One major bottle neck here is the access to marine lipids. Both salmon and people needs poly unsaturated fatty acids (PUFA like DHA og EPA) to stay healthy. Hence, in the long run the demand for PUFA will become a major challenge. The current and growing future pressure on world pelagic resources to cope with the increased needs of these ingredients to the aquaculture industries is a clear cut sustainability issue. At the same time this will also exert pressure on prices on these natural resources, a reason why lipids from farmed microalga may become price competitive not far from now. Hence, cultivation of microalgae, is by the sector now pointed at as one of a few major ways in addition to starting sustainable harvest at various trophic levels in the oceans (krill and calanus spp etc). MareLife members are involved in R&D, in pilot stages and in business in these fields now. MareLife has been involved in a series of workshops, conferences at national, Nordic and international levels with microalgae on the agenda. Recently and currently we are also undertaking market analysis and inventories in the field within the framework of the Blue Bio project, together with Norwegian Seafood Federation and the Storby Marin network. The prices of algae based lipids (omega-3 etc) for feed and human consumption are still too high to be competitive, but there is a dynamic developments in technology and scaling (Photobioreactors, dewatering, processing etc) which will make this approach competitive over time. Moreover, the microalgae option contains a sustainable dimension by being socalled autotrophice (produce advanced nutrional compounds: proteins, lipids, carbohydrates, essential molecules etc from inorganic matters) through energy efficient processes (photosynthesis, biophotolysis etc), spending waist and light mostly, not least being carbon capturing “machines”.

GENETIC FINGERPRINT -A MareLifeflagship projectthat reveals fromwherethesalmon has escaped

By combining DNA-based assignment analysis (parents vs. offspring) with information on logistics, it is possible in a very cost effective way for the industry, and without significant change in logistics routines to trace escaped salmon back to farm.

THE MARELIFE NEWS • JULY • 2012

Project manager Sissel Kjøglum, AquaGen, proofing the concept of genetic tracking of escaped salmon.

- Elimination of fish farms among potential "suspects" candidates when it comes to escaped salmon is possible on the same basis. DNA-based parentage test connected with controlled /documented logistics of genetically defined batches, is the most robust of all strategies for the genetic tracking of farmed fish, says MareLife managing director Øystein Lie. A study initiated and co funded by the Norwegian Seafood Federation and VRI Oslo-Akershus and brought forward by MareLife shows how DNA can help tracking escaped farmed salmon. The main principle for DNA tracking of salmon consists of the following two components: 1) DNA database of foodfish parents. All fish parents (eventually 40-50 thousand annually) is tested and DNA-typed with genetic markers (SNP or microsatellites). 2) Logistics management and el-tracking of uniqe gentic batches to the hatchery further on to grow out. When an escapee case arise, the potential "runaway" is genotyped with the same marker set as the parent panel. With adequate software one can track the fish to the right parents and the right fish farm is revealed. These efforts will enhance the industry reputation, with the signal that it has control of the biomass. It means also a safe elimination of players who cannot have caused salmon escape, but who could have been under suspicion. The method is also a new tool to generate completely new knowledge about the interaction between culture fish and wild fish and thus be able to mobilize more qualified data and facts, and potentially reduce conflicts that can be established on the wrong basis. Based on a MareLife report by Sept. 2011, three new development projects have been initiated: 1) "Proof of concept - genetic tracking of escaped salmon." Supported by VRI and The Aquaculture Environmental Fund (project manager Sissel Kjøglum AquaGen and project coordinator/owner MareLife) 2) "Tracing the Origin of Farmed Atlantic Salmon escapees by DNA parentage assignment: Optimizing Methods and Real-Life Validation Studies." (R & D project with emphasis on SNP-chip technology for improved tracking to farm and to distinguish farmed salmon from wild salmon. (Coordinating partner Norwegian School of Veterinary Sciences)

3) "Trace Salmon - Industry wide Tracing of Norwegian Farmed Atlantic Salmon." (Microsatellite based tracking approach, lead partner Nofima) the two latter project are supported financially by the Norwegian Seafood Research Fund. Internationally, there is nothing comparable to this project, intending to lay the foundation for an entire nationwide farming industry DNA based tracking of fish. The value added of this project may embrace important implications like the following: ->Strengthened reputation ->Safe elimination of innocent serious players ->Improved logistics control and batch identity/definition ->Improved alert capacity ->Extended breeding tool (extended no of informants) ->Protection of brands ->Distinguishing between wild and cultured fish ->Improved knowledge about the interaction between cultured and wild populations

GREEN VESSEL – aparadigmshiftinfishery

technology- NASF2012award Liegruppen in collaboration with Rolls Royce, Telenor Marine, NIVA, IMR, SINTEF Fishery and Aquaculture and Veritas assisted by MareLife and Oslo Maritime network are jointly moving forward the fishery technology. Together they are addressing the following key issues for enhanced sustainability in fishery: HSG (hybrid shaft generator for energy effiency and reduced emission), (Two step ICT solution to strengthen the decision base for the man on the bridge), Remote sensors to monitor ocean environmental parameters, multisite acoustics, holistic technology packaging, “green passport”. For this forerunner concerted effort Liegruppen received NASF 2012 Innovation award for best systems innovation.

THE MARELIFE NEWS • JULY • 2012

Columbia, Genome Atlantic, Health Canada, The Research Council of Norway, the Norwegian Ministry of Trade and Industry, and the Korean Ministry of Land, Transport and Maritime Affairs, hosted the conference. Marelife published “Blue Frontier Magazine” to the conference in Vancouver. The magazine was distributed to the invited participants at the Global Forum. You can read the magazine here: http://issuu.com/businessmemo Link to presentation from Global Forum on Biotechnology, Vancouver: http://www.oecd.org/document/48/0,3746,en_2649_34537_4954 4368_1_1_1_1,00.html

Other allies:

MareLife Holland, Icland Ocean Cluster, the Nordic Center of Excellence for research on Climate Change and Ocean Resources, "NorMer" at University of Oslo (CEES).

BLUE BIO - TheBlueBio project, EU InterregIVA

This cross border project commenced January 1st, 2011 and will be finalized Dec. 31st, 2012. The projects partners are UMB, Kjeller Innovasjon, Gothenburg University, Chalmers and MareLife as the Norwegian project owner.

Marelife published “Blue Frontier Magazine” to the conference in Vancouver.

BUILDING ALLIANCES - OECDtakes alookatmarine biotechnology

In May Øystein Lie was one of the keynote speakers at a major conference on marine biotechnology in Vancouver, Canada: “OECD Global Forum on Biotechnology: Marine Biotechnology Enabling Solutions for Ocean Productivity and Sustainability.” This event was the first time the OECD has taken a systemic look at what marine biotechnology could contribute to the grand challenges of food and fuel security, population health, green growth and sustainable industries. The meeting aimed to increase the awareness among policymakers on the food potential of the marine environment, a potential to be realised through marine biotechnology. Lie participated in session 1: “Productivity and sustainability of the ocean”. The session discussed the potential contributions of oceans to economic prosperity on a global level and to the maintenance or improvement (sustainability) of the planet’s ecosystem. Lie’s presentation was titled: “Preparing for global food demands by 2050 – living marine resources and marine biotechnology response”.

The conference hosts

The OECD, in partnership with Genome Canada, Genome British

The main issue is to assist commercialization of marine concepts and in this process Blue Bio has developed a manual for early stage commercialization. The project team collaborates tightly with the NASF team for the purpose to rig and expose cases at this major arena. Blue Bio assisted at developing the innovation sessions (Day Zero) at North Atlantic Seafood Forum (NASF), where a series of BlueBio´s cases were exposed at great success. The project has backed R&D based cases in their commercialization process, such as filing for patents. Some of these cases are: Algae as high-grade feed components to fish, Algae and yeast to reduce enteritis in salmon and Fish vaccines IPN and Winter Ulcer. The project, which has received funding from EU (Interreg IVA), Oslo Municipality, Akershus County Council and Innovation Norway, has a broad marine technical and commercial sector approach and has put the ’hot topic’ of micro-algae forward as a pilot by carrying out a market analysis for microalgae.

LONDON MEETING - MareLifeatBioMarine Convention

Marelife collaborates with BioMarine Convention, an international platform dedicated to marine bio resources, that brings together executives and CEOs from marine ingredients, marine cosmetics, marine nutraceuticals, aquaculture, aquafeed, marine bio energy, pharmaceuticals and clean tech. On 24 and 25 October 2012, Øystein Lie will be among the 250 executives and CEOs meeting in London to share their experience whilst developing their business opportunities. London 2012, The 3rd BioMarine International Business Convention is based on a new think tank approach, will focus essentially on constructive and practical exchanges. Every attendee will take part of the discussions and become a real player of our BioMarine community. Link: http://ww.biomarine.org

THE MARELIFE NEWS • JULY • 2012

The MareLife headquarter - at the Oslo Innovation Center.

BIO VALUE - Bioeconomy2020: Value creationoflifescience

"BioVerdi" (Bio Value) is the working title of a new joint project that is expected to create added value of life science. The project has been very well received in all environments, from universities and industry to venture capital sector. Top executives have expressed specific interest in and support for the project “BioVerdi” will be a continuation of the "Bioeconomy 2020", a project in Oslo Innovation Center that focuses on measures for innovation for bio industries, and which, among other puts biomarine innovation on the agenda. In Vision 2020, bio-based industries are supposed to be a major source of value creation and business growth in the Oslo region and Norway, a development to which the project “Bio Verdi” will give an important contribution. “BioVerdi” is a cross field and trans boundary initiative to develop a stronger "ecosystem" of innovation. The project will be established in partnership between leading R&D units, industry representatives from bio production and pharma, capital owners and with support from public policy system and authorities. The project owners are to discuss and agree on the final goal, vision and strategy for “Bio Verdi” and what the project is to be formally named. The partners commitment and ownership to the project are based on a planning document written by Øystein Lie. Proposed ownership structure, steering committee and working groups will be available shortly. The project aims to have drawn up an action plan for

implementation before year end. “Bio Verdi” seeks to establish an International Advisory Board, represented by the Nordics, UK, USA and Singapore. “BioVerdi” intends to try to connect to “The Norwegian Industrial Biotechnology Network”, as a possible pilot or demonstration project.

Top executives from the following companies and organizations support fundamental principles in the planning document: R&D units:

Oslo (UiO) University Hospital (OUS) – in progress Norwegian University of Life Sciences (UMB), Norwegian School of Veterinary Science (NVH) Norwegian Institute for Water Research (NIVA) NOFIMA – in progress Norwegian Business School (BI)

Industry:

Human Health/Pharma/Nutrition: Pronova Biopharma, Algeta – in progress, Clavis – in progress, Vitas – in progress Marine: AquaGen, the network MareLife Agriculture: Nortura – in progress, Graminor – in progress Manufacturing /bio refining: Agroplas, Borregaard – in reference group

Finance/TTO/Commercialisation:

Norwegian Venture Capital & Private Equity Association (NVCA) Verdane Capital Inven2 Kjeller Innovation – in progress Oslo Innovation Center – incl. secretarial functions/project management

THE MARELIFE NEWS • JULY • 2012

project BioValue will connected to IBN as a pilot, says Øystein Lie. The newly elected board consists of the following 9 persons: Kjartan Sandnes (Marine Bioproducts AS), Ragnhild Borgrevink (Viken Skog AS), Hans Kristian Kotlar (Statoil), Johanne Brendehaug (Tine SA), Jan Buch Andresen (Arcticzymes AS), Anne Hjelle (Iris), Trond Ellingsen (Sintef), Hans Kleivdal (university of Bergen), Vincent Eijsink (University of Life Science).

SUMMER TIME -wewishyouaniceandrelaxing summer!

Ole Jørgen Marvik (left) and Merlin Goldman (right) from the Technology Strategy Board – British partner of Innovation Norway.

BIOTECH NETWORK - to advanceNorway's biotech industries

Profitable and sustainable business is the common denominator for the 36 players, including several MareLife members, who have gathered in the recently established network: The Norwegian Industrial Biotechnology Network. They will cooperate to find solutions to the enormous challenges and business potentials ahead in areas such as food production, climate change and energy supply. Fuel and plastic bottles from seaweed, biogas from waste, cosmetics from algae, artificial silk from trees, “from wood to food” (Borregaard slogan) or enzymes from shrimp water: The potential of applied biotechnology is enormous. Through longterm investments, Norway has already expertise in biotechnology, which provides opportunities to build new knowledge-intensive industries based on renewable resources from the marine sector, agriculture and forestry. New technology, especially biotechnology, and the need to replace oil with renewable raw materials are the main drivers behind the emerging bio economy. - The most important industrial revolution in the 21st century is the transition from petroleum to renewable, bio based products. Today, oil is the basis of 90 per cent of the world chemical industry. The world must optimize the use of renewable resources while we develop environmental technology, says Gunn Ovesen, CEO of Innovation Norway in a statement. Innovation Norway, SIVA (The Industrial Development Corporation of Norway) and The Research Council of Norwegian are the initiators of the new biotechnology network which had its inaugural meeting in Oslo June 13.. The network has high ambitions: The goal is to find solutions to challenges in food production, raw material shortages, environmental pollution, energy and climate change. The world population is expected to increase to nine billion by 2050, and in the same period, the food needs increase 70 percent and energy demand by 100 percent. The network's main task is to stimulate innovation through collaboration across sectors, knowledge sharing and to stimulate new projects and industrial partnerships. The networks activities bring together academia and industry across research disciplines, industry sectors and geography. - The network will be an instrument for realizing the Government's national strategy for biotechnology and make contact with international research institutions and markets, says Ole Jørgen Marvik of Innovation Norway, a driving force of this initiative, in the statement. MareLife and several of its members will contribute to the new industrial network IBN. - The MareLife project portfolio is also linked with the networks projects, e.g. through algae activities. Also the

MareLife wishes you a relaxing summer, with lots of sun and nice seafood! Be prepared for an active MareLife autumn, winter and spring season with a number of projects and activities to be launced. Here are some main points for what is coming up: * Late September. Aquaculture and environments: Seminar on the new an reinforced environment responsibility program of the aquaculture sector. Overview talk by representative from the Norwegian Seafood Federation *Late November: DNA-vaccines. International meeting in collaboration with the Norwegian Biotechnology Advisory Board *R&D and startups. Follow up on our R&D projects in operation and preparing for new: DNA tracing of escapees, Microalgae, testbed for marine ingredients to address health claims, green fishery technology, preparing for NASF 2013. Assist startups and R&D concepts with commercial potentials * Algae analysis and project preparation and preparatory phase to reactivate former Marbed-concept: test bed to validate marine ingredients for health claim approval.

Enjoying delicous seafood is never wrong - also in the summer time. Picture: Marine Harvest

Carl Seip Hanevold, chairperson MareLife: "Through my long standing career in the marine sector I have learned to focus on the main issues of the sector: disease control, escaped fish, enhanced broodstocks, feed resources, sustainable business in all phase and to communicate to the public that this is an industry for the future, providing the most healthy food and that we are aware of our challenges and that we are addressing them. I am happy to confirm that Marelife is on the right track and delighted and happy to be able to serve and to share my experience with this important organization."