Antibody Engineering Services
Various Antibody Engineering Formats Creative Biolabs has focused on the antibody engineering field for decades and established a series of platforms including various antibody engineering services. A wide range of formats are available, including IgG, Fab, scFv, and CARs, for therapeutic use.
Our Services The goal of antibody engineering is to combine various antibody domains to generate customized antibodies that show specialized binding properties, optimal half-lives and desirable effector functions. Our antibody engineering services are summarized as below.
Antibody Reformatting and Production
Epitope Binning and Mapping
Offer multiple different antibody formats, Fab, F(ab)’2, scFv, VHH, minibodies, etc.
Identify the epitope of an antibody and elucidate the mechanism of binding for an antibody.
Antibody Humanization
Affinity Measurement
Utilize a variety of methods and toolkits in the antibody humanization process.
Help clients to determine the kinetic properties of antibody-antigen interactions.
Affinity Maturation
Immunogenicity Prediction
Combine molecular evolution and high-throughput phage library construction and screening.
Perform in vitro screening, in vivo screening and in silico assessment by SIAT platforms.
Sequence Liability Identification
Therapeutic Developability Assessment
Select liability-free antibodies for further development and reduce cost by foreseeing risks.
Evaluate the candidates’ drug-like manufacturability, physicochemical properties, and safety profiles.
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