Antibody Maturation
Overview of Antibody Affinity Maturation We’d like to conduct antibody optimization, antibody affinity maturation service that combines molecular evolution and high-throughput phage library construction and screening to improve antibody potency and to save the cost of antibody production.
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Design phage library and perform library construction: 2 -3 weeks;
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High-throughput phage library screening: 1.5-2 months;
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Construction and expression of recombinant antibodies: 2-3 weeks.
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Antibody affinity measurement: 2-3 weeks.
Antibody Maturation by Phage Displays The in vitro affinity maturation has been used to optimize antibodies, antibody fragments or peptide molecules. Our HIAF-ProNano™ Platform can increase the affinity of single domain antibodies by engagement of protein nanocages without changing physicochemical properties.
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