Antibodies for T Cell Co-Signaling Research Increase Your Efficiency and Value with Consistent Performance Antibodies: detection, imaging, diagnostic, etc. info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for T Cell Co-Signaling Research Your Antibody Solution Provider Perfect for your pilot studies As a leading antibody service provider with extensive experience in a variety of antibody production and engineering fields for both basic scientific research and pharmaceutic industries, Creative Biolabs offers high-quality ready-to-use catalogue antibodies, as well as flexible and comprehensive customized services for the antibody production. With high level professional scientists and advanced antibody production platform, we are dedicated to offering various antibodies for a wide range of applications, and designing a specific antibody project to tailor the service to best fit your program.
Trusted Antibody Quality
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Antibodies for T Cell Co-Signaling Research T Cell Co-Signaling T cell activation requires two signals. One is recognition of the antigenic peptide/major histocompatibility complex (MHC) by the T cell receptor (TCR); another is antigen independent co-stimulation induced by interactions between co-signaling molecules expressed on antigen-presenting cells (APCs) and their T cell-expressed receptors.
Co-stimulatory and Co-inhibitory molecules Engagement of the TCR in the absence of this second co-stimulatory signal typically results in T cell anergy or apoptosis. In addition, T cell activation can be negatively regulated by co-inhibitory molecules present on APCs. Therefore, integration of the signals transduced by co-stimulatory and co-inhibitory molecules following TCR engagement directs the outcome and magnitude of a T cell response including the enhancement or suppression of T cell proliferation, differentiation, and/or cytokine secretion.
(Chen and Flies, 2013, Nat Rev Immunol)
A Quick Glance at Key Types of T Cell Co-Signaling Kind reminder: If you are interested in any other targets, please visit our website or contact us.
Ig Superfamily
TNF Superfamily
B7/CD28 families; Butyrophilis; Nectin and nectin-like binding receptors; SLAM family; TIM family receptors & ligands.
Type V Subfamily Receptors & Ligands; Type L Subfamily Receptors & Ligands.
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Antibodies for T Cell Co-Signaling Research Popular antibodies for Ig Superfamily Many of Ig suprfamily molecules are being investigated as potential therapeutic targets for cancer immunotherapy, since they have shown anti-tumor activity via immunity pathways. Creative Biolabs provides antibodies to help facilitate your T cell co-signaling research within budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.
Antibodies for B7/CD28 Families Targets
Clone
Applications
Species reactivity
Cat.No.
6N36 2E5 1E2F10 IT2.2 GL1 CBFYC-1466
F, IH, N, WB IC/IF, IH, P, WB E, C, WB F, FN F, IF, IH, IP F, IH, IP, WB
Human Human Human, Mouse, Pig Human Mouse Human
CBMAB-C8378-LY CBMAB-C5006-LY CBMAB-C3931-LY CBMAB-C4995-CQ CBMAB-C3032-CQ CBMAB-C1524-FY
B7-H1/ PD-L1
10F.9G2
B
Mouse
CBMAB-1081-LY
B7-H2/ ICOS L
HK5.3
N
Mouse
CBMAB-1021-LY
B7-H3
MJ18
B, F
Mouse
CBMAB-0957-LY
MH5A MIH63 MM0741-29N17 CBYY-1762 CBFYH-1066 CBYY-1764 4D6 PJ196
F F WB B, IC, F WB F, MC WB, IC/IF B, A, F
CBMAB-P3787-YC CBMAB-V0191-LY CBMAB-G6682-LY CBMAB-2111-YY CBMAB-H2010-FY CBMAB-2113-YY CBMAB-C6797-LY CBMAB-0961-LY
CBYY-0904
WB, IH
CD28.2 1D5 204.12 CBYJT-3537 CBYJT-3536 CBYJT-3535 BN13 CBXC-2930 9D9 CBYY-I0795 27A12 CBYY-C0578 J116 J110
WB, F, IH, IF, C E, WB F, IH, C, MC WB, IP, IF, E F, MC F, IH, MC N, F WB, F, E, IF N, WB E, F, N, WB F, IH, FN, IP, C F, FN, N, B N, B F
Mouse Mouse Human Human Mouse, Rat, Human Human Human Mouse Human, Mouse, Rat, Monkey, Dog Human, Primate Human Human, Mouse Human Human Human Human Human, Mouse Mouse Human Mouse mouse Human Human
TY25
B
Mouse
CBMAB-1082-LY
B7-1/ CD80
B7-2/ CD86
B7-H5/ VISTA/ PD-1H B7-H7/ HHLA2
BTLA
CD28 CD28H/ IGPR-1 CTLA-4
ICOS PD-1 PD-L2/ B7-DC
CBMAB-0907-YY CBMAB-C0532-CQ CBMAB-C3842-LY CBMAB-C0581-LY CBMAB-T2862-YJ CBMAB-T2861-YJ CBMAB-T2860-YJ CBMAB-0932-LY CBMAB-C0234-CQ CBMAB-1009-LY CBMAB-I1772-YY CBMAB-I0231-YY CBMAB-C1820-YY CBMAB-0943-LY CBMAB-0942-LY
To be continued.
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Antibodies for T Cell Co-Signaling Research Antibodies for Butyrophilins Targets
Clone
Applications
Species reactivity
Cat.No.
BTN1A1/ Butyrophilin
4A11 CBYY-0907 CBYY-0908
WB F, IF, WB IF, WB
Human Human Human, Dog, Rat, Monkey
CBMAB-0023-YC CBMAB-0910-YY CBMAB-0911-YY
BTN2A1
CBYY-0920
F
Human
CBMAB-0923-YY
BT3.1 CBXC-1338 CBYY-0921 CBYY-0924
F F F, IP WB
Human Human Human Human
CBMAB-C0440-CQ CBMAB-C1606-CQ CBMAB-0924-YY CBMAB-0927-YY
CBYY-0923
IH, WB
Human
CBMAB-0926-YY
BTN3A1/ CD277 BTNL2/Butyro philin-like 2
Antibodies for Nectin and Nectin-like Binding Receptors Targets CD96
CD155/ PVR
CRTAM DNAM-1/ CD226 Nectin-2/ CD112
Nectin-3/ CD113 TIGIT
Clone
Applications
Species reactivity
Cat.No.
NK92.39 6A6 CBXC-1661 D171 CBFYC-3071 3F1 21A9 CBXC-2516 CBFYC-2236 1X20 DX11 CBYCD-529
F, FN F, FN, IA, WB E, F, WB F, FN, IF E, WB, IP F, FN C, WB WB, F E WB, P, B, N F, FN, IP E, WB
Human Mouse Mouse Human, Monkey Human Mouse Human Human Human Human Human Mouse
CBMAB-C4981-CQ CBMAB-C1575-YY CBMAB-C2947-CQ CBMAB-P3545-YC CBMAB-C3148-FY CBMAB-C0326-YY CBMAB-C4398-LY CBMAB-C0923-CQ CBMAB-C2306-FY CBMAB-D0066-YC CBMAB-D0067-YC CBMAB-D0070-YC
13A61
E, F, C, IP, WB
Mouse
CBMAB-P0546-YC
CBWJN-0430 11E1 N3.12.4 103-A1 1D1 1G9 CBYJT-3141 CBYJT-3146
E, F, IH, IP, WB WB, E, IP FM, IC, IPP E, F, IH, IP, WB E, WB F F, MC F
Human, Mouse Mouse Human Mouse Human Mouse Human Mouse
CBMAB-N1731-WJ CBMAB-C2426-LY CBMAB-N1740-WJ CBMAB-N1737-WJ CBMAB-P0552-YC CBMAB-1097-LY CBMAB-T2412-YJ CBMAB-T2417-YJ To be continued.
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Antibodies for T Cell Co-Signaling Research Antibodies for SLAM Family Targets
Clone
Applications
Species reactivity
Cat.No.
2B4/ CD244/ SLAMF4
2B4.69 CBLQC-001 7D24 3H1461 7H198 CBYY-C1477 2D11-B10
F, P WB, EC, P WB F, IF, C, WB E, C, WB E, IC, WB E, IF, P, WB WB, IP, E, C, N, F, B, IC, IF C, WB F, IC, IF, C, IP E, F, IC, WB F
Human Human Human Human, Monkey Human Goat, Human Human
CBMAB-1865CQ CBMAB-2045CQ CBMAB-C8620-LY CBMAB-C1176-LY CBMAB-C8807-LY CBMAB-C2915-YY CBMAB-C4867-LY
Mouse, Human
CBMAB-L0217-YJ
Human Human Human Mouse
CBMAB-C9207-LY CBMAB-S6564-CQ CBMAB-S3370-CQ CBMAB-C2631-CQ
CD48/ SLAMF2
CD58/ LFA-3
SLAM/ CD150
CBYJL-146 8G24 SHM-57 CBXS-0418 CBXC-1401
Antibodies for TIM Family Receptors & Ligands Targets Galectin-3 TIM-1/ KIM-1/ HAVCR TIM-3
TIM-4
Clone
Applications
Species reactivity
Cat.No.
15H199 CBYJL-1522 4i288 3F4 RMT1-10
IF, WB E, IF, IH, WB, siRNA E, IC, IF, IH, WB E, F, WB E, F, IF
Cattle, Human, Mouse, Rat Human, Mouse, Rat Human, Mouse, Rabbit, Rat Human Mouse
CBMAB-G6225-LY CBMAB-L1288-YJ CBMAB-G6241-LY CBMAB-K0357-LY CBMAB-T0368-YJ
CBFYH-3519
WB, IC, P, C, E
Human
CBMAB-H4070-FY
8B.2C12 CBYY-C0698 CBYJT-1358 CBYJT-3161 RMT4-54 CBYJT-3155
F, IH, IP F, IH, IP, FN F, IH, IP, WB IA, IC, IF, FN FN, P, IC, IF, F E, IF, IP
Mouse Mouse Human Mouse Mouse Human
CBMAB-C9049-LY CBMAB-C2051-YY CBMAB-T0377-YJ CBMAB-T2435-YJ CBMAB-T2434-YJ CBMAB-T2427-YJ To be continued.
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Creative Biolabs owns comprehensive antibody products and related services. Please contact us for more detailed information and our team will get back to you as soon as possible. We are always here to serve you the best to help promote your projects. The lists only exhibit a small part of our products. Please visit our website or contact us for more detailed information.
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Antibodies for T Cell Co-Signaling Research Popular antibodies for TNF Superfamily Like Ig superfamily, TNF superfamily is also investigated as potential targets for cancer immunotherapy, which consists of type V and type L subfamily receptors and ligands. Creative Biolabs provides antibodies to help facilitate your T cell co-signaling research within budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.
Antibodies for Type V Subfamily Receptors & Ligands Targets 4-1BB/ TNFRSF9/ CD137 4-1BB Ligand/ TNFSF9 CD27/ TNFRSF7
CD27 Ligand/ TNFSF7 CD30/ TNFRSF8 CD30 Ligand/ TNFSF8 GITR/ TNFRSF18 GITR Ligand/ TNFSF18 OX40/ TNFRSF4 OX40 Ligand/ TNFSF4
Clone
Applications
Species reactivity
Cat.No.
CBFYC-0113
E, F, IC, IF
Mouse
CBMAB-C0130-FY
6D295
E, C, WB
CBMAB-C8194-LY
4B4 (4B4-1)
E, IP, F, FN
TKS-1
B
Mouse Human, Chimpanzee, Baboon, Cynomolgus, Rhesus monkey Mouse
014
E, F, IC/IF, IF
Mouse
CBMAB-C0047-LY
CBYJT-4018
E, F, FN, WB
Human
CBMAB-T3432-YJ
LG.8A6
E, F, IP
Mouse
CBMAB-C3424-CQ
LG.7F9
F, IP, FN
Human, Mouse, Rat
CBMAB-C0809-CQ
1C1G3
E, IF, C, WB
Human
CBMAB-C3719-LY
BU69
F, IC, C, IP
Human
CBMAB-C2438-CQ
7H173
E, F, IC, IH
Human
CBMAB-C8792-LY
14L233
E, N
Mouse
CBMAB-C3128-LY
15B3
IC/IF, C, P
Human
CBMAB-C3254-LY
3B10
F, E, WB
Human
CBMAB-C5681-LY
CBYJT-3877
P, IF, IC, F
Human
CBMAB-T3272-YJ
3G56
WB
Human
CBMAB-C6161-LY
CBYJT-4014
F, IH, FN, IP
Mouse
CBMAB-T3427-YJ
CBYJT-4010
E, WB
Human
CBMAB-T3423-YJ
7C13
P, F
Mouse
CBMAB-G6637-LY
CBYJT-3773
E, WB, IH
Human, Mouse
CBMAB-T3156-YJ
CBFYC-3173
ED, E F, N, WB
Human
CBMAB-C3250-FY
CBYJT-3971
F, N
Human
CBMAB-T3383-YJ
6D415
E, F
Mouse
CBMAB-G6651-LY
CBYJT-3987
E, F, WB
Mouse
CBMAB-T3399-YJ
CBXO-0487
F, IH, C, MC
Mouse
CBMAB-O0896-CQ
7D6
F, WB
Cat, Human
CBMAB-O0015-CQ
CBXO-0385
WB, F, MC
Human
CBMAB-O0039-CQ
CBYJT-3998
F, FN, IP, WB
Mouse
CBMAB-T3411-YJ
CBYJT-3991
IH, FN, F, N
Human
CBMAB-T3404-YJ
OX89
F, FN, IH
Mouse
CBMAB-O0081-CQ
CBMAB-C0800-YY CBMAB-0954-LY
To be continued.
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Antibodies for T Cell Co-Signaling Research Antibodies for Type L Subfamily Receptors & Ligands Targets CD40/ TNFRSF5 CD40 Ligand/ TNFSF5 DR3/ TNFRSF25
HVEM/ TNFRSF14
LIGHT/ TNFSF14
TL1A/ TNFSF15
Clone
Applications
Species reactivity
Cat.No.
G28.5
F, IH, IP, MC
Human
CBMAB-C0673-CQ
3B2
E, C, WB
Human
CBMAB-C5702-LY
1C10
F, C, IP
Mouse
CBMAB-C0485-LY
TNFSF5
B
Mouse
CBMAB-0969-LY
11H6L9
F, IC, IF, WB
Human, Mouse
CBMAB-D2329-YC
4C12
AG, F
Mouse
CBMAB-D2331-YC
7H65
E, IH, WB
Mouse
CBMAB-D2334-YC
Laury-1
F, IC, IF, IP
Human
CBMAB-T3128-YJ
CBFYH-2797
WB, F, MC, EC
Human
CBMAB-H0058-FY
7H150
E, F
Human
CBMAB-C8777-LY
CBYJL-2374
WB, IP, IF, P, E
Human
CBMAB-L2683-YJ
15B2
E, IP
Mouse, Human
CBMAB-C3247-LY
CBYJT-3949
E, IC, IH, WB
Human
CBMAB-T3356-YJ
Tingo-1
E, IP, WB
Mouse
CBMAB-T3380-YJ
TLRM1-1
WB, P, IF, IC, F
Human
CBMAB-T3374-YJ
CBYJT-3957
WB, B, N
Human
CBMAB-T3364-YJ
Clone
Applications
Species reactivity
Cat.No.
4
IP, F
Human
CBMAB-C1175-FY
CNX46-3
F, WB
Rat
CBMAB-N4376-WJ
1D4B
IC
Mouse
CBMAB-N0646-WJ
2G4
E, WB
Human
CBMAB-C5185-LY
Plc12AT
E, WB, IF
Human
CBMAB-L0498-YJ
CBYJL-2416
E
Mouse
CBMAB-L2744-YJ
Antibodies for Others Targets CD160
LAIR1
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Antibodies for T Cell Co-Signaling Research Antibody Services Guidance What's my target?
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Antibodies for T Cell Co-Signaling Research Highlight Features: Innovative technologies and ideas Numerous worldwide customers High-level Ph.D. scientists and experienced technicians High efficiency and short turnaround time Close collaboration Extensive forefront knowledge sharing Advanced and one-stop platforms
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With extensive experience and over a decade superior antibody services for numerous worldwide customers, Creative Biolabs has blossomed into a service leader in the field of antibody products and services. We offer a comprehensive set of package services and also individual modules, and aim to maximize the success of your T cell co-signaling research.
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