Complement Factor D (CFD), encoded by gene CFD in humans, is a serine protease that catalyzes the cleavage of factor B, the initial proteolytic step of the alternative pathway of complement activation. Factor D was originally identified as adipsin, a cell signaling protein secreted by adipocytes, myeloid cells, and hepatocytes, which regulates fat deposition and insulin secretion in mice.https://www.creative-biolabs.com/complement-therapeutics/complement-factor-d.htm