PIK3CA antibody for breast cancer

Antibodies for Breast Cancer Research Increase Your Efficiency and Value with Consistent Performance Antibodies: detection, imaging, diagnostic, etc. info@creative-biolabs.com www.antibody-creativebiolabs.com

Antibodies for Breast Cancer Research High-quality & validated antibodies for all your needs Creative Biolabs offers high quality ready-to-use catalogue antibodies, as well as flexible and comprehensive customized services for the antibody production to facilitate the basic discovery of breast cancer. Empowered by extensive experience and senior teams, we are committed to offering cuttingedge antibodies with superior performance for a wide range of applications to best maximize the success of your projects at the forefront of technological innovation.

Trusted Antibody Quality

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Antibodies for Breast Cancer Research Breast Cancer Breast cancer is the principle cause of cancer-related mortality among women worldwide. It's highly heterogeneous and can be classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+).

Types, frequency and associated mutant genes TNBC Triple-negative breast cancers are ER-PR-HER2- and show significant but not complete overlap with the basal-like subtype of breast cancer (which is defined by differentiation state and gene expression profile).

TNBC 10% HER2+ 20%

HER2+ breast cancers have luminal features and are characterized by ERBB2 gene amplification and overexpression, leading to a dependency on HER2 signaling.

Luminal, non-HER2+ 70%

Luminal (non-HER2+) tumors are typically estrogen receptor positive, displaying high ERα levels.

These tumors are dependent on estrogen for growth and, therefore, respond to endocrine therapy.

A Quick Glance at Key Targets in Breast Cancer Kind reminder: If you are interested in any other targets, please visit our website or contact us.

Commonly mutated targets

Key markers • • • •

ESR1 HER2/ERBB2 Ki67 Progesteron receptor (PGR)

• • • • • •

TP53 PIK3CA GATA3 MAP3K1 MLL3 CDH1

• • • • • •

USH2A PTEN RUNX1 NCOR1 RB1 TBX3

• • • • • •

PIK3R1 CTCF NF1 SF3B1 AKT1 CBFB

• •

FOXA1 CDKN1B

Key signaling factors • • • • • •

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SRC RAS BRAF MEK1 MEK2 ERK1/MAPK3

• • • • • •

ERK2/MAPK1 MAP2K4 JNK/MAPK8 STMN2 PIK3R1 PIK3R3

• • • • • •

AKT2 PTEN MDM2 p53 TBX3 GSK3B

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• • • • • •

Cyclin D1/CCND1 Cyclin D3/CCND3 CDK4 PRB1/2 NCOA3 MYC

• • • • • •

MYB FOXA1 GATA3 CBFB RUNX1 NCOR1

• •

TBL1XR1 p16Ink4A /CDKN2A

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Antibodies for Breast Cancer Research Antibodies for commonly mutated targets Targets TP53 PIK3CA GATA3 MAP3K1 MLL3 CDH1 USH2A

PTEN

RUNX1 NCOR1

RB1

TBX3

PIK3R1

CTCF

NF1

Clone

Applications

Species reactivity

Cat.No.

1285C CBWJW-083 1F7 CBYC-P379 H.843.0 4F3 1A12-1D9 7B5 CBLG1-676 CBFYM-0114 9D8 3A10 CBFYM-1193 1686CT202.60.69 CBYY-C0043 3G44 3G42

WB, IHC, IF, P, FC WB, P, PE IP, M, WB WB, IP, IC, IF P, IP, WB WB, E, F, IC, IF IC, IF, P, IP, WB E, IH, P, WB IC/IF, P, IP, WB F, IF, P, WB WB E, F, IC, IF, WB WB, E WB IS, WB, IF, IH, IP F, IF, IH, IP, WB E, F, IF, IH, IP, WB

Human, Mouse Human, Mouse, Rat Human Human Cattle, Human,Mouse, Rat Human Human, Mouse, Rat Human Human Human Human Human, Mouse Human Human Human, Dog, Mouse, Rat Human, Mouse Human

CBMAB-1838CQ CBMAB-T0002-WJ CBMAB-0266-LY CBMAB-P1796-YC CBMAB-P1797-YC CBMAB-P1795-YC CBMAB-G2217-LY CBMAB-G2223-LY CBMAB-G2244-LY CBMAB-M0132-FY CBMAB-1022-YC CBMAB-1021-YC CBMAB-M1350-FY CBMAB-K1430-LY CBMAB-C0119-YY CBMAB-C6150-LY CBMAB-C6148-LY

CBXU-038

WB

Human

CBMAB-U0154-CQ

10BA33

IF, WB

CBMAB-1516CQ

D4.3

WB, IP

1B8 CBYC-A1038 15B RXDMC 7A7A9 CBWJN-0129 9BA9 Rb1 (1F8) CBXC-2448

E, F, IC, IF, WB F E, IC, P, WB F E, IH, P, WB E, IH, WB E, WB IH, IF WB, P, C

CBXC-2426

WB, IF

CBYJT-2161 CBYJT-2160 CBYJT-2158

WB, IP, IF, E WB, IP, F WB, E, P, F, IC, IF

U5

C, IP, WB

2E7 8C11 2B12E2 1D11 CBXC-1870 2D1 A-12

E, M E, WB, P, IF, IC, F E, WB, IF E, WB WB, IH, P E, WB WB, IP, IF, P, E

CBWJN-0652

WB, E, IP, P

Human Human, Mouse, Rat, Hamster, Monkey, Dog, Chicken Human, Mouse Human, Monkey Human Human, Mouse Human Human Human Human Human, Mouse Human, Mouse, Rat, Dog, Primate, Rabbit Human,Rat, Mouse Human,Rat, Mouse Human Cattle, Human,Mouse, NonHuman primate, Rat Human Human, Mouse Human, Mouse Human, Monkey Human Human mouse, rat, Human Human, Mouse, Rat, Guinea Porcine

CBMAB-P3310-YC CBMAB-P3306-YC CBMAB-A4717-YC CBMAB-A4712-YC CBMAB-R3861-CN CBMAB-N1470-WJ CBMAB-N1469-WJ CBMAB-1448CQ CBMAB-C1002-CQ CBMAB-C0046-CQ CBMAB-C0034-CQ

CBMAB-T1266-YJ CBMAB-T1265-YJ CBMAB-T1263-YJ CBMAB-P1817-YC CBMAB-0832-CN CBMAB-P1814-YC CBMAB-C4674-LY CBMAB-C3807-LY CBMAB-C5096-CQ CBMAB-N2125-W CBMAB-N2129-WJ CBMAB-N0290-WJ

To be continued.

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Antibodies for Breast Cancer Research Antibodies for commonly mutated targets Targets SF3B1

AKT1 CBFB FOXA1

CDKN1B

Clone

Applications

CBXS-5436

WB

CBXS-2265 CBXS-1300 4E10 4C3 5C10 A-4 8C84 1E6 3C1 2D7 CBXF-3132 SX53G8 0.N.491 CBLC-LY-008

WB, IP, IF, E WB, P, IF WB, IH, IF, F E, IP, PLA, RNAi E, WB WB, IP, IF, E DB, C, WB IP, WB, M WB, E, P, IF E, WB, IH IC, IH, WB P F, IF, IH, IP, WB F, IF, C, P, IP, WB

Species reactivity Human, Mouse, Rat, Monkey, Hamster, Cattle Mouse, Rat, Human Human Human,Dog, Rat, Monkey, Mouse Human Human,Mouse, Rat, Dog Human Human Human Human Human Human, Mouse Human,Mouse, Rat, Primate Dog, Human,Mouse, Rat Mouse

Cat.No. CBMAB-S2647-CQ CBMAB-S5027-CQ CBMAB-S4159-CQ CBMAB-A2050-YC CBMAB-A2048-YC CBMAB-A2053-YC CBMAB-P0143-YC CBMAB-C9108-LY CBMAB-0194-YC CBMAB-F0941-CQ CBMAB-F2967-CQ CBMAB-F3828-CQ CBMAB-P0194-YC CBMAB-P0188-YC CBMAB-C9407-LY

Popular antibodies for key markers

Creative Biolabs' antibodies help meet your breast cancer research needs and budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.

ESR1 The anti-ESR1 antibody shows obvious nuclear positivity in human breast tissue using IHC. By western blot analysis, ESR1 is clearly detected around 68KDa. Targets

Clone

Applications

Species reactivity

Cat.No.

ESR1

ESR1/420 2G112B3 CBFYE-1267

WB, F, IF E, WB IC, IH, IP, WB

Human Human Hamster, Human, Mouse, Rat

CBMAB-E0318-FY CBMAB-1204-YC CBMAB-E1850-FY

Applications

Species reactivity

Cat.No.

F, E, IH, MC

Human

CBMAB-E1659-FY

P, WB F, IF, C, P, IP, WB

Human, Mouse, Rat, Monkey Human

CBMAB-E1645-FY CBMAB-E1648-FY

HER2/ERBB2 The anti-HER2 antibody shows distinct membranous positivity in HER2-negative and positive ductal carcinoma.

Targets

Clone

HER2/ ERBB2

4D5-8 (TrasTuzumab) SPM495 9G6

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Antibodies for Breast Cancer Research Ki67 The anti-Ki67 antibody shows obvious nuclear positivity in human lymph node via IHC. By ICCIF, Ki67 is detected in nucleoli of human cell line U-2OS. Targets

Clone

Applications

Species reactivity

Cat.No.

Ki67

3D11 4A1 SP6

IH, P, WB IA, IH IH, IC/IF, P, C

Human Human Human, Mouse, Rat, Dog

CBMAB-K2136-LY CBMAB-K2137-LY CBMAB-K2173-LY

Progesteron receptor (PGR) By immunofluorescence and immunohistochemistry, PGR is detected in MCF-7 cell and formalin-fixed paraffin-embedded human breast cancer tissue.

Targets

Clone

Applications

Species reactivity

Cat.No.

PGR

4E9 0.N.529 8A11H1

E, IF, P, WB IF, IH, IP, WB WB

Human Equine, Human,Pig, Sheep Human

CBMAB-P1613-YC CBMAB-P1605-YC CBMAB-P1614-YC

Popular antibodies for key signaling factors

Key signaling pathways involved in breast cancer include RAS/RAF, RAS/MAPK, PI3K/AKT etc.

Creative Biolabs provides a wide range of antibodies for involved signaling factors, but not limited to these. Please contact us for more products information.

Targets SRC

RAS BRAF

MEK1

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Clone

Applications

CBXS-3318

F, IC, IH, IP, WB

CBXS-2306 CBXS-1773 Y13-259 1C8 CBFYH-1953 15B239 CBYY-2086 CBYY-1674 25/MEK1 CBFYM-1441

IC, IP, WB IH WB WB WB, IH, IF WB IH, P, WB F, IC, IH, P, WB F WB, P, IF, IP

CBFYM-1438

WB

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Species reactivity Cattle, Hamster, Human, Monkey, Mouse, Rat Chicken Human Mouse, Rat, Human Human, Monkey Human, Dog, Rat, Monkey, Mouse Human, Mouse Human, Dog Human Human, Chicken, Dog, Mouse, Rat Human, Mouse, Rat, Zebrafish Dog, Human, Mouse, Non-human primate, Rat

Cat.No. CBMAB-S6057-CQ

CBMAB-S5068-CQ CBMAB-S4590-CQ CBMAB-G6077-LY CBMAB-G6073-LY CBMAB-H2964-FY CBMAB-R0430-CN CBMAB-2435-YY CBMAB-2023-YY CBMAB-M0108-FY CBMAB-M1601-FY CBMAB-M1598-FY

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Antibodies for Breast Cancer Research Antibodies for key signaling factors in breast cancer Targets MEK2 ERK1/MAP K3 ERK2/MAP K1

MAP2K4

JNK/MAPK 8

STMN2

PIK3R1 PIK3R3 AKT2

PTEN

MDM2

p53 TBX3 GSK3B

Clone

Applications

Species reactivity

Cat.No.

CBFYM-1465

WB, E, F, IF

CBMAB-M1625-FY

CBFYM-1456

F

CBFYM-1455 3C9 1E5 12D11 4F3-A10-E7 CBFYM-1574 4C11 CBXS-4988 CBXS-5919

F, IC, IF, WB E, IC, IF, P, IP, WB E, P, F, IC, IF, WB WB, CI, IH, IF, P WB E, WB, IH, IC E, IC, IF, IH, C, P, WB F, IF, IH, P, IP, WB F, IF, IH, P, WB

CBFYM-1486

WB, IP

Mouse, Rat, Human Human, Chicken, Dog, Frog, Mouse, Rat Human Human Human, Mouse, Rat, Monkey Human, Mouse, Primate Human,Mouse, Rat Human, Mouse, Rat, Sheep Human, Mouse, Monkey Human Human, Dog Human, Mouse, Rat, Monkey, Dog

41/JNK/SAPK (pT183/pY185)

WB

Human, Mouse, Rat

CBMAB-0199-WJ

H.715.7

IP, WB

2F3 CBXS-3507 CBXS-1399 CBXS-0804 8C11 2E7

WB, IP, E, P E, WB WB, IP SE, E, WB E, WB, P, IF, IC, F E, M

U13

WB, IP

2F8 CBYC-P386 5B5 AW114 D16-H 10BA33

E, PLA, WB WB, P, IC, IF WB, IP WB, IP E, WB, IF, IC, IP IF, WB

D4.3

WB, IP

1B8 CBFYM-1965 CBFYM-1964 CBFYM-1961 7A4 CBWJW-083 CBLG1-2390 CBYJT-2161 CBYJT-2159 CBYJT-2160 E.948.2 3A11 3D6B4

E, F, IC, IF, WB E, F, IC, IF, WB E, WB, IH IC, IF, IH, IP, WB IF, IH, IP, WB WB, P, PE IF, SE, E, WB WB, IP, IF, E E, IC, WB WB, IP, F P, IP, WB E, WB WB, F, E, IH, MC

Hamster, Human, Mink, Mouse, Primate, Rat Human Human Mouse, Rat, Human Human Human, Mouse Human Mouse, Rat, Cattle, Human, Monkey Human Mouse, Rat, Human Human,Mouse, Rat, Monkey Human, Rat Human,Mouse, Rat Human Human, Mouse, Rat, Hamster, Monkey, Dog, Chicken Human, Mouse Mouse Human, Mouse, Rat Human Common fruit fly Human, Mouse, Rat Human Human,Rat, Mouse Human Human,Rat, Mouse Human, Mouse, Primate, Rat Human, Mouse, Rat Human, Mouse

CBMAB-M1616-FY CBMAB-M1615-FY CBMAB-1195-YC CBMAB-1192-YC CBMAB-E2167-FY CBMAB-P0477-YC CBMAB-M1740-FY CBMAB-1201-YC CBMAB-S2210-CQ CBMAB-S0768-CQ CBMAB-M1646-FY

CBMAB-0363-WJ

CBMAB-0148-WJ CBMAB-S6236-CQ CBMAB-S4257-CQ CBMAB-S3731-CQ CBMAB-P1814-YC CBMAB-0832-CN CBMAB-P1816-YC CBMAB-P1824-YC CBMAB-P1825-YC CBMAB-A2093-YC CBMAB-A2101-YC CBMAB-A2102-YC CBMAB-1516CQ CBMAB-P3310-YC CBMAB-P3306-YC CBMAB-M2140-FY CBMAB-M2139-FY CBMAB-M2136-FY CBMAB-0433-LY CBMAB-T0002-WJ CBMAB-G6398-LY CBMAB-T1266-YJ CBMAB-T1264-YJ CBMAB-T1265-YJ CBMAB-G5224-LY CBMAB-G0845-LY CBMAB-H1379-FY

To be continued.

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Antibodies for Breast Cancer Research Antibodies for key signaling factors in breast cancer Targets

Clone

Applications

Species reactivity

Cat.No.

Cyclin D1/CCND 1

CD1.1 SP4

WB, F, E, IH, IP, P, C WB, IH, IF, P

Human, Rat Human, Mouse, Rat, Baboon

CBMAB-C4698-CQ CBMAB-C4697-CQ

CBXC-1590

E, F, IH, IP, WB

Human, Rat

CBMAB-C4700-CQ

Cyclin D3/CCND 3

CBYY-C0337 CBFYC-1042

WB, IH F, IF, IH, IP, N, WB

Human Human, Mouse, Rat

CBMAB-C1127-YY CBMAB-C1099-FY

CBFYC-1040

WB, IF, IH, IP

Mouse, Dog, Human, Rat

CBMAB-C1097-FY

CDK4

5J210 3F9-B12-C8 0.N.199

IF, IH, IP, WB WB, E IF, IP, WB

Human, Mouse, Rat Mouse, Rat, Dog, Human, Pig Human, Mouse, Pig, Rat

CBMAB-C7749-LY CBMAB-C6085-LY CBMAB-C1404-LY

PRB1/2

BA0343

WB, P

Human

CBMAB-0690CQ

NCOA3

AX15.3 AC3 F-2

Human Human mouse, rat, Human

CBMAB-S2958-CQ CBMAB-N0184-WJ CBMAB-N1451-WJ

Human, Mouse, Chicken, Yeast

CBMAB-C9324-LY

3G32 CT14.G4 10A3 D-12 4-E3 4F6 CBFYH-0203 SP88 1A12-1D9 7B5 CBLG1-676 A-4 4D9 CBYY-C1023 CBYC-A1038 15B RXDMC 7A7A9 CBWJN-0129 9BA9

E, IH, P, IP, WB, CI WB, IH, IF, P WB, IP, IF, E WB, CI, F, E, IH, IP, P, C, MC E, IF, IH, IP, WB F, IF IP, WB WB, IP, IF, E WB, IP E, IF, P, WB WB, IP, IF, P, E F, P IC, IF, P, IP, WB E, IH, P, WB IC/IF, P, IP, WB WB, IP, IF, E IP, WB, M DB, IC, WB F E, IC, P, WB F E, IH, P, WB E, IH, WB E, WB

CBMAB-C6137-LY CBMAB-C0609-CQ CBMAB-V0114-LY CBMAB-A4588-YC CBMAB-A4587-YC CBMAB-F2445-CQ CBMAB-H1077-FY CBMAB-F0220-CQ CBMAB-G2217-LY CBMAB-G2223-LY CBMAB-G2244-LY CBMAB-P0143-YC CBMAB-0199-YC CBMAB-C2460-YY CBMAB-A4717-YC CBMAB-A4712-YC CBMAB-R3861-CN CBMAB-N1470-WJ CBMAB-N1469-WJ CBMAB-1448CQ

CBYJT-2103

E, WB, IH, IC

CBYJT-2102 CBYJT-2105 5-C3-1 2D9A12 1E12E10

WB, E, P, IC WB, IP, CI IF, IH, IP, WB WB, P WB, P

Human, Mouse Human, Primate Human, Mouse, Zebrafish Mouse, Rat, Human Human, Mouse, Xenopus Human Mouse, Rat, Human Human Human, Mouse, Rat Human Human Human Human Human Human, Monkey Human Human, Mouse Human Human Human Human,Mouse, Rat, Cattle, Pig, Dog, Zebrafish Human,Mouse Human, Monkey Mouse Human Human, Mouse, Rat

9E11

MYC

MYB

FOXA1

GATA3

CBFB

RUNX1

NCOR1

TBL1XR1

p16Ink4A /CDKN2A

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CBMAB-T1202-YJ CBMAB-T1201-YJ CBMAB-T1204-YJ CBMAB-C7387-LY CBMAB-C4943-LY CBMAB-C3919-LY

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Antibodies for Breast Cancer Research “ Creative Biolabs offers comprehensive antibody products and related services. Please contact us for more detailed information and our team will get back to you as soon as possible. We are always here to serve you to help promote your projects. The list above only exhibits a small part of our products. Please visit our website for more information. https://www.antibody-creativebiolabs.com

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Antibodies for Breast Cancer Research Highlight Features: Innovative technologies and ideas Numerous worldwide customers High-level Ph.D. scientists and experienced technicians

High efficiency and short turnaround time Close collaboration Extensive forefront knowledge sharing Advanced and one-stop platforms

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With extensive experience and over a decade superior antibody services for numerous worldwide customers, Creative Biolabs has blossomed into a service leader in the field of antibody products and services. We offer a comprehensive set of package services and also individual modules, and aim to maximize the success of your breast cancer research discovery and development.

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Custom Antibody Service Process

Submit protein sequence

Antigen design

Antigen synthesis

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Quality control

Delivery

A wide range of applications WB

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IHC

ELISA

IP/ChIP

IF/FC

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Functional assay

Expedite Your Breast Cancer Research Leverage the expertise of our senior scientists to obtain a wide array of antibodies or custom products to fit your project.

Tel: 1-631-381-2994 Fax: 1-631-207-8356 Email: info@creative-biolabs.com

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The trusted antibody and custom service & solution provider.

Our promise: Guaranteed product quality, expert customer support.

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