Human genome project has shed the light on understanding the human gene functions. Of the roughly 35,000 genes in the human genome, only a few have been identified as known genes. Therefore, validating and verifying a positive lead is the key to effective drug development. Developing a drug against a specific target is an extensive commitment in terms of time and money. Target validation is a crucial step in the drug discovery pipeline. Generally, a drug target is the specific biomolecule to which the drug is directed or binds, resulting in a change due to its action. New drug validation underlies the new drug exploration and the initial step of drug discovery. It is of great help to drug research and also provides more insight for understanding the pathogenesis of the diseases.https://www.creative-biolabs.com/drug-discovery/therapeutics/gene-silencing.htm
