Different from the CAR technology which can be utilized to only recognize antigens expressed on tumor cell surface, TCR technology can recognize tumor specific antigens inside of tumor cells. After the tumor associated proteins are broken into small specific antigen, they will be presented to cell surface by major histocompatibility complex (MHC).https://www.creative-biolabs.com/immuno-oncology/t-cell-receptor-tcr-t-cell-therapy.htm
