Strategy for targeting to the Liver
In liver-specific applications, the main types of carriers have been examined, such as polymers, lipid-based nanoparticles. Unlike the passive targeting approach without further identification of the intrahepatic cell types that take up the drug, active targeting is using specific modules that can recognize and bind to a certain type of cells in liver.
https://www.creative-biolabs.com/targeted-delivery/targeting-liver.htm