CHeBA Annual Report 2021

Page 14

Brain Ageing Research Laboratory This interdisciplinary group was formed to apply state-of-the-art molecular biology techniques to the advancement of research in the areas of normal ageing, Alzheimer’s disease and other agerelated neurodegenerative conditions. The team consists of neuroscientists, protein and analytical chemists, psychiatrists and bioinformaticians working in Australia and abroad. CHeBA’s Brain Ageing Research Laboratory was a sole recipient of a $1 million research grant from The Yulgilbar Foundation to develop nanoparticles as nanodiagnostics and nanotherapeutics in Alzheimer’s disease. The group utilises human and murine brain cell cultures and postmortem tissue for understanding the brain and the ageing process. Our current work is committed to discovering the fundamental causes and possible treatments for agerelated neurodegenerative disorders such as Alzheimer’s, and neurodevelopmental diseases, as well as on genetic and metabolic changes that take place as organisms grow old. Our cross-disciplinary and integrative approach using clinical samples and animal models will facilitate the detection of dementia-related changes in the preclinical stages and validate the efficacy of targeted novel early interventions for neurocognitive disorders. The group also has the expertise to culture, propagate, differentiate, engineer and transplant in animal models the neural stem cells from various sources including skinderived neuroprogenitors and human mesenchymal stem cells from bone marrow.

In addition, we have expertise in the derivation of new human embryonic stem cell lines including their clonal propagation.

Dr Nady Braidy Group Leader Staff Professor Perminder Sachdev

PhD Students Chul-Kyu Kim Marina Ulanova

Dr Nady Braidy, Chul-Kyu Kim, Maria Villalva, Gurjeet Virk and Marina Ulanova

12

Maria Villalva

Gurjeet Virk


Turn static files into dynamic content formats.

Create a flipbook
Issuu converts static files into: digital portfolios, online yearbooks, online catalogs, digital photo albums and more. Sign up and create your flipbook.
CHeBA Annual Report 2021 by CHeBA - Issuu