CHeBA Annual Report 2021

Page 14

Brain Ageing Research Laboratory This interdisciplinary group was formed to apply state-of-the-art molecular biology techniques to the advancement of research in the areas of normal ageing, Alzheimer’s disease and other agerelated neurodegenerative conditions. The team consists of neuroscientists, protein and analytical chemists, psychiatrists and bioinformaticians working in Australia and abroad. CHeBA’s Brain Ageing Research Laboratory was a sole recipient of a $1 million research grant from The Yulgilbar Foundation to develop nanoparticles as nanodiagnostics and nanotherapeutics in Alzheimer’s disease. The group utilises human and murine brain cell cultures and postmortem tissue for understanding the brain and the ageing process. Our current work is committed to discovering the fundamental causes and possible treatments for agerelated neurodegenerative disorders such as Alzheimer’s, and neurodevelopmental diseases, as well as on genetic and metabolic changes that take place as organisms grow old. Our cross-disciplinary and integrative approach using clinical samples and animal models will facilitate the detection of dementia-related changes in the preclinical stages and validate the efficacy of targeted novel early interventions for neurocognitive disorders. The group also has the expertise to culture, propagate, differentiate, engineer and transplant in animal models the neural stem cells from various sources including skinderived neuroprogenitors and human mesenchymal stem cells from bone marrow.

In addition, we have expertise in the derivation of new human embryonic stem cell lines including their clonal propagation.

Dr Nady Braidy Group Leader Staff Professor Perminder Sachdev

PhD Students Chul-Kyu Kim Marina Ulanova

Dr Nady Braidy, Chul-Kyu Kim, Maria Villalva, Gurjeet Virk and Marina Ulanova

12

Maria Villalva

Gurjeet Virk


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Appendix G: Publications

51min
pages 105-114

Appendix E: Research Grants & Funding

10min
pages 99-103

Appendix C: Postgraduate Students

7min
pages 95-97

Appendix D: Awards & Promotions

2min
page 98

Completed Projects

26min
pages 83-90

Current Projects

1hr
pages 63-82

CHeBA Collaborators

8min
pages 58-62

Public Forums

2min
page 56

WithYou

1min
page 52

CHeBA in the Media

5min
pages 53-54

KPMG Sydney Commits to Ongoing Support for The Dementia Momentum

2min
page 47

Change Makers – Next Gen Philanthropy

8min
pages 48-50

The Dementia Momentum - Spokesman’s Report

2min
page 46

Sydney Centenarian Study

2min
page 41

PhD Completions

5min
pages 42-43

Sydney Memory and Ageing Study

7min
pages 38-40

Maintain Your Brain

1min
page 36

Older Australian Twins Study

2min
page 37

SHARED

2min
page 32

STROKOG

6min
pages 33-35

COSMIC

2min
page 31

COGNISANCE

6min
pages 28-30

Risk Factors

2min
pages 26-27

Neuropsychiatry

2min
page 22

Genomics & Epigenomics

2min
pages 18-19

Proteomics

0
page 25

Neuroimaging

3min
pages 20-21

Neuropsychology

3min
pages 23-24

Epidemiology

1min
page 17

Effect of COVID-19 Greatest on People Living with Dementia

1min
page 9

Researching Aged Care, Policy and Education

1min
pages 12-13

About the Centre

2min
pages 6-7

CHeBA Launches Dementias Platform Australia to Make Study of Ageing ‘Truly Global’

2min
page 11

Brain Ageing Research Laboratory

5min
pages 14-16

Co-Directors' Report

3min
pages 4-5

CHeBA Funding Success to Transform ‘Preventable Dementia

1min
page 8

Can Fluid-Filled Spaces in the Brain Predict Dementia?

1min
page 10
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