CHeBA Annual Report 2021

Page 26

Risk Factors The Risk Factors Group studies risk factors for dementia from a lifespan perspective. The group uses large-scale population-based studies, neuroimaging data, and epidemiological modelling to understand the risk factors for dementia across the lifespan. One of the main focuses of the Risk Factors Group is alcohol use, and its impact on brain health in foetal development, adolescence, and later life. The group has used longitudinal cohorts from CHeBA (the Sydney Memory and Ageing Study) as well as CHeBA’s consortia (COSMIC) to investigate the relationship between alcohol use and dementia in later life. In collaboration with the Global Burden of Disease Study, the Risk Factors Group is also using COSMIC data to better understand the contribution of a range of risk factors to mortality and morbidity associated with dementia globally. The Risk Factors Group also focuses on developing and evaluating novel online behaviour change interventions aimed at reducing risk factors that contribute to the development of dementia in later life.

Dr Louise Mewton Group Leader Staff

Virginia Winter Sarah Davies Rachel Visontay Nicholas Hoy

Opinion Piece Launched Rethink My Drink In November the Risk Factors Group launched Rethink My Drink, a world-first online study designed to help Australians aged 60-75 years consider their alcohol consumption and be guided to reduce their intake and help prevent dementia. Low levels of alcohol use, between 1 and 7 standard drinks per week, are associated with small but significant changes in the brains of older adults, with heavy drinkers three times more likely to develop dementia. One large and influential study has even identified heavy drinking as the single most dangerous risk factor for dementia - when compared with other modifiable lifestyle risk factors. Most recent evidence indicates that one in five Australians over 60 exceeds official guidelines of more than two drinks per day, putting themselves at risk of long term harm - higher than any other age group. Leader of the Group, Dr Louise Mewton, said it is critical for Australians over 60 to be aware that heavy alcohol use is the strongest modifiable risk factor for dementia in comparison to such things as smoking, obesity, high blood pressure and diabetes. The world-first study aims to determine whether an online alcohol brief intervention adapted for older adults can slow cognitive decline, while at the same time reduce alcohol consumption in older risky drinkers.

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https://cheba.unsw.edu.au/news/festive-seasonopportunity-address-alcohol-concerns If you are concerned about your alcohol consumption and would like to participate in this study, register your interest at www.unswalcoholstudy.org.au


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Appendix G: Publications

51min
pages 105-114

Appendix E: Research Grants & Funding

10min
pages 99-103

Appendix C: Postgraduate Students

7min
pages 95-97

Appendix D: Awards & Promotions

2min
page 98

Completed Projects

26min
pages 83-90

Current Projects

1hr
pages 63-82

CHeBA Collaborators

8min
pages 58-62

Public Forums

2min
page 56

WithYou

1min
page 52

CHeBA in the Media

5min
pages 53-54

KPMG Sydney Commits to Ongoing Support for The Dementia Momentum

2min
page 47

Change Makers – Next Gen Philanthropy

8min
pages 48-50

The Dementia Momentum - Spokesman’s Report

2min
page 46

Sydney Centenarian Study

2min
page 41

PhD Completions

5min
pages 42-43

Sydney Memory and Ageing Study

7min
pages 38-40

Maintain Your Brain

1min
page 36

Older Australian Twins Study

2min
page 37

SHARED

2min
page 32

STROKOG

6min
pages 33-35

COSMIC

2min
page 31

COGNISANCE

6min
pages 28-30

Risk Factors

2min
pages 26-27

Neuropsychiatry

2min
page 22

Genomics & Epigenomics

2min
pages 18-19

Proteomics

0
page 25

Neuroimaging

3min
pages 20-21

Neuropsychology

3min
pages 23-24

Epidemiology

1min
page 17

Effect of COVID-19 Greatest on People Living with Dementia

1min
page 9

Researching Aged Care, Policy and Education

1min
pages 12-13

About the Centre

2min
pages 6-7

CHeBA Launches Dementias Platform Australia to Make Study of Ageing ‘Truly Global’

2min
page 11

Brain Ageing Research Laboratory

5min
pages 14-16

Co-Directors' Report

3min
pages 4-5

CHeBA Funding Success to Transform ‘Preventable Dementia

1min
page 8

Can Fluid-Filled Spaces in the Brain Predict Dementia?

1min
page 10
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