Cleanroom Magazine 03 2015 by Cleanroom Future

summer 2015

Joy of Being Driven

How the vision of autonomous driving is gradually becoming a reality

Smart Textiles Intelligent fabric changes medicine, architecture, fashion and the car industry

Operating Theatre This is what the surgery workstation of the future looks like

Save the Date! Vision. Innovation. Expertise. 27 + 28. 10. 2015 Frankfurt am Main

International trade fair and congress for cleanroom technology. No matter what type of cleanroom you require, Cleanzone offers innovative and interdisciplinary solutions for every sector. You will find more information and impressions at: www.cleanzone.messefrankfurt.com

Dear Readers, Innovative companies grow faster, generate more revenue and are more novation conducted in 25 countries by the accounting and consulting company PricewaterhouseCoopers (PwC). Many of these innovative companies become successful with products produced in cleanrooms. Among these are first of all automotive suppliers, but also medical technology manufacturers and textile producers. Their innovations pave the way to a future that might look like this: you Reap the rewards: The most innovative companies are growing at a much faster rate over the next five years | Source: PwC study of innovation. Interview partners 1,757 executives in 25 countries

get into your car after work, say “Home,” and grab your newspaper. Your Frank Duvernell »A study by the auditing firm

car does the rest on its own. When it reaches your house, it parks itself in

PricewaterhouseCoopers came to interesting

the garage while you’re getting ready to go jogging. Your evening run gets

results. Two-thirds of the most innovative companies think that innovations are neces-

your pulse pounding. But don’t worry: your smart sports shirt is monitor-

sary for competition. Are the expenditure for

ing your heart function. If you overexert yourself, your smart shirt will

research and development worth it? Definitely

call the doctor.

yes. The study says that innovative companies have a three times higher rate of growth,

Speaking of the doctor: in the future, when the man in the white coat reach-

as the study results in the graph shows at the

es for his scalpel, he will be assisted by high-resolution visualization sys-

right.«

tems and robotic arms with haptic feedback for high-precision navigation through the tissue. Operations will be considerably safer, just like doing sport and driving a car. In our new issue, you will read about how this bright future is no longer a distant vision, but is actually within reach. Companies with cleanroom technology have a big part to play in this, and the Cleanroom Academy recognizes them each year with the Cleanroom Award. Join us! Applications on the topics of innovation, sustainability and energy efficiency will be accepted until August 31. You can find out what to do in the following pages. P.S.: Efficiency isn’t everything. Sometimes beauty counts, too. That’s why the Cleanroom Academy is presenting a second award this year for the most beautiful cleanroom! I hope you enjoy your reading.

Frank Duvernell Editor 2/2015

EDITORIAL

successful in the long run. That is the conclusion reached by a study of in-

CONTENTS 03/2015

..................................................

08 CONTENTS

08 Cover Story: The joy of being driven

How the vision of autonomous driving is gradually becoming a reality with clean room products.

..................................................

LIFE & BUSINESS

News from the world of cleanrooms

06 Market activity in brief • Chip demand for photovoltaic inverters increases • Cleanroom technology becoming ever more important for Turkey • Next generation of high performance electronics • Faster overview with microdrones • Pharmaceutical industry stands up for TTIP • Mass extinction from multi-resistant organisms? • Samsung is building the world‘s largest chip factory

..................................................

18 Smart Textiles: when textiles think ahead Federal Transport Minister Alexander Dobrindt testing a self-navigating Audi. Photo: Audi AG

Miniaturized electronic components from cleanroom fabrics provide intelligent functions. These intelligent substances change medicine, architecture, fashion and car industry.

..................................................

24 Next generation operating room: digital scalpels

Surgeons are increasingly supported by high-tech systems. Navigation technology, visualization systems and robotics open up completely new possibilities in the operating room.

.................................................. 30 Insights: On the road with ... Dietmar Pfennig, CEO PPS Pfennig Reinigungstechnik GmbH (Cleaning Technology GmbH) Surgical Deck: How the operating room of the next generation looks like. Photo: Acqua Klinik

2/2015

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5 SCIENCE & TECHNOLOGY

Foto: Archiv

Solutions for the world of cleanrooms

32 Technology in brief • New surgical centre for University of Munich • Computer chip made of wood • New material for the production of artificial blood vessels • High-tech machine for cleanroom goggles • North Korea claims to have a miracle drug against MERS • Sensors for industrial applications 4.0

.................................................. 34 Cleanroom Design:

an end to the white noise

Colour in the clean room increases well-being and ability to concentrate. Photo: archive

Coloured cleanrooms improve concentration and reduce the rejection rate. Contrary to popular belief, a nicely designed cleanroom doesn’t cost much more than a white one.

..................................................

38 Guest post: The effect of colour in a cleanroom

Colour psychologist Alfred Schleicher warns of physiological problems from white working environments and lists alternatives.

.................................................. 40 Cleanroom Management:

Professionalism is in demand

Cleanrooms must be managed professionally. Only then can high product quality be achieved on a permanent basis.

The Cleanroom Award 2014 won Initial. For 2015, the Award application period runs until the end of August. Photo: Sandra Gätke

.................................................. 44 Clothing Management:

Clothes make cleanroom people

To reliably protect products from contamination, a well designed clothing management system is necessary in addition to highly functional cleanroom fabrics.

SERVICE

Events, Awards, fixed categories

..................................................

50 Law and regulations: The new Annex 15

Damaris Steyernagel, pharmaceutical technical assistant (PTA)

On October 1, 2015, the revision of Annex 15 “Qualification and validation” of the EU GMP Guide will come into force. The most important changes at a glance.

48 What do you do...?

................................................

................................................ 52 Participate: Apply now for the Cleanroom Award

For the first time, a design award for the most beautiful clean room will be awarded in addition to the Cleanroom Award for Innovation of the Year at the CleanZone.

................................................

................................................ 55 Im Interview: Beat Toniolo

Worauf der schweizer Künstler als Juror des Design-Awards „Schönster Reinraum“ bei den Bewerbungen besonders achtet.

................................................

56 CL-EX.com: Cleanroom knowledge for everyone

The Portal www.CL-EX.com has a unique collection of cleanroom knowledge. Technical articles, videos, checklists and much more is available to users.

................................................ 58 Events

................................................ 60 Site Notice

................................................

2/2015

Life&Business

LIFE & BUSINESS

Market Development in a Nutshell

Increase of chip demand for photovoltaic converters

Turkey can become to the cleanroom technology centre

The next generation of high performance electronics

Study | The market for semiconduc-

Fair |“Since the Cleanroom Exhi-

Research | The European research

tors used in photovoltaic converters

bition held from 16th to 18th April

project “Seven-Nanometer Tech-

will grow strongly in the next four

2015 in Istanbul, it is obvious that

nology” has been started. A goal of

years. According to the latest study

cleanroom technology has become

42 European partners from science

by the California market research

a new, highly interesting, and inno-

and industry is the development

firm HIS, with more than 8,000 em-

vative market in Turkey,“ says Fatih

of high-precision, high-speed ma-

ployees in 31 countries - one of the

Onkar, General Manager of Exhi-

chines, production processes, and

biggest „global information compa-

bition organizer Akdeniz Tanitim.

measurement techniques for the

nies“, the turnover of semiconduc-

The fledgling cleanroom industry

production of next-generation chips.

tor chips for solar converters will

in Turkey is growing in the busi-

These structures should be only sev-

increase by 12 per cent in 2015, by 20

ness fields of health, medicine, elec-

en nanometers wide. This means

per cent in 2016, by 14 per cent in 2017,

tronics and food. „The strategical-

halving the structure size of the best

and by 16 per cent in 2018.

ly well-situated location of Turkey,

chips available today. Compared with

with its leading cleanroom compa-

the state of the art ten years ago, it

nies. is a centre for the eastern Med-

is even miniaturizing by one tenth.

iterranean countries and is a bridge

The project focuses on the devel-

to the countries of the Middle East,“

opment of new lithography equip-

said Fatih Onkar. From here, provi-

ment for the structuring of the chip.

sion of cleanroom services for customers as far away as Russia, India, and the Middle East is possible. Market analysts expect an annual double-digit sales growth of chips for photovoltaic converters in the next four years. Photo: Vasily Smirnov / fotolia

„One of the main trends in the semThe chips of the future will have structures

iconductor industry is to develop

only seven nanometers wide. Photo: Pavel

solutions enhancing energy efficien-

Timofeev

cy,“ said IHS Director Robbie Galoso.

For this, the optical lenses used up

Therefore, semiconductors played a key role for photovoltaic converters because they enabled huge energy savings.

2/2015

Impression of the Cleanroom Exhibition in Istanbul. Photo: Akdeniz Tanitim

to now must be replaced by a complex system of mirrors. The project runs until 2018.

7 Further miniaturization of the structure sizes on the one hand and in

Mass extinction by multi-resistant germs?

kilometres, Samsung intends to produce (amongst others) semiconductor products for mobile devices, serv-

their demand on the other has no end in sight. The impacts of clean-

Antibiotics | According to a study

ers and the Internet of Things. Up to

room technology are obvious. We

commissioned by the Green Party

150,000 jobs could be created with this

will know a lot more by 2018..

in the German Parliament (Bunde-

project. The amount of cleanroom

stag), the number of deaths due to

jobs amongst these 150,000 is at the

multi-resistant germs may increase

moment still unknown.

Detailed overview with micro drones

from the present 700,000 per year to ten million worldwide by 2050. The

Pharmaceutical industry is strongly committed to TTIP

Monitoring | Researchers at the Al-

reason is the indiscriminate use of

pen Adria University in Klagen-

antibiotics in human medicine and

furt, Austria have developed a sys-

in intensive livestock farming. Ac-

tem that creates current overview

cording to the study, if the state of

Patient Benefits | The pharmaceu-

images from single images of micro

things does not change, the death toll

tical industry sees the Free Trade

drone cameras. Previously, this was

in Europe alone could rise from the

Agreement TTIP between the EU

difficult because of different flight

current 23,000 to 400,000. That means

and the US as a great opportuni-

altitudes and camera orientations as

more people would die because of

ty for companies and beneficial

well as lower image overlaps.

multi-resistant germs than of cancer.

to patients. Studies prior to drug

One-tenth of all hospital-acquired

approval will not have to be done

The new Klagenfurt method elimi-

infections is now considered mul-

twice, and the US and EU health in-

nates these disadvantages by extract-

ti-resistant. This means that they can

spectors will not both need to vis-

ing characteristic features from the

no longer be fought with antibiotics.

single images and using similarities to generate the overview picture. Another advantage is that the extracted image features are on one level and thus a low distortion representation is achieved. As opposed to a simple “hobby drone”, the method is suitable for getting

The pharmaceutical industry is awaiting harmonized rules and savings from TTIP.

more detailed results based on photographic material. Rescue teams can use it in floods or wildfires, but also

Escalating antibiotic use spurs pathogens to become multi-resistant. Photo: Lupo /pixelio

Samsung builds world’s largest chip factory

it the production facilities in order to check the same things. Moreover, in the view of the pharmaceutical industry, the harmonized rules would benefit patients, mostly because of lower prices. Howev-

Billions invested | The South Kore-

er, some experts fear that the op-

an conglomerate Samsung plans to

posite may occur, since prices in

build the world’s largest production

Europe and the US are set accord-

site for semiconductors by 2017. It will

ing to different schemes and it can-

spend a record sum, equivalent to

not be assumed that the pharma-

EUR 12.7 billion. With the new factory

ceutical companies will pass their

for environmental monitoring, for

in the South Korean city of Pyeong-

savings in to the health insurance

site documentation or for agricul-

taek, Samsung strives to become the

system.

tural observations.

largest semiconductor manufacturer

A new method generates an overview picture from micro drone single images. Photo: Lakeside Labs

in the world. At the moment, this is the US Intel Corporation. The new location, comprising about 2.89 square

2/2015

LIFE & BUSINESS

Federal Transport Minister Alexander Dobrindt aboard an Audi - in autonomous mode „Piloted Driving“. Image: Audi AG

2/2015

The Joy of Being Driven

How the vision of autonomous driving is gradually becoming a reality.

2/2015

The Joy of Being Driven

LIFE & BUSINESS

How the vision of autonomous driving is gradually becoming a reality.

The International Motor Show Germany will be held from September 15, 2015 to September 27, 2015 in Frankfurt am Main with the focus on „automated driving“ and „connected cars.“ Thanks to technical developments, self-driving and communicating cars on our roads are only a matter of time. Whether it involves measuring distances, reading road signs or responding to gestures, systems that enable autonomous driving contain clean room components. Motorists may be familiar with this

eye movements and warn of fatigue.

concept: Take your hands off the

Optical sensor systems are moving

steering wheel, pick up a book or

into the display, so that the radio,

Smartphone and get chauffeured

navigation system, phone or even

to your destination by the car. As if

the windows can be controlled with

by magic, the traffic organizes itself.

short gestures.

son, director of the Self-Driving Car Project”, presented the Google car prototype. He promised, “We will carefully bring this car on the road.” The pace at which Google is moving ahead may concern some motorists who are critical of automation.

Vehicles merge into a line one after the other, smoother than a driver of flesh and blood could ever accom-

Google moving ahead

plish. Even parking at the destina-

The Google Car. Photo: Google

tion won’t raise your pulse. Better

The vehicle of the future is being

yet: you can legally drive home in

worked on everywhere, not on-

Urmson already announced in May

your own car after a visit to a restau-

ly in Stuttgart or Munich, but al-

that the Google car was now leaving

rant or beer garden. Alcohol limit?

so in Detroit and Tokyo, and espe-

the test course and would show up

No problem.

cially in Mountain View, California,

in real traffic.

where Google is headquartered, and What seemed unthinkable just a

of course in China as well. Google

They may have gotten to this point

few years ago is increasingly with-

made the most recent headlines.

quite rapidly, but that doesn’t mean

in reach. Efforts to develop intelli-

The IT group, who like no other, be-

there wasn’t a lot of work involved.

gent, networked, self-driving cars

lieves so consistently in the feasi-

Google has already collected a lot of

are at full-bore all around the globe.

bility of future visions, launched a

experience with self-driving cars in

Clean room products assist in this

program to create self-driving cars

real traffic. Google engineers have

endeavor. With optoelectronic sys-

in 2010. In January 2015 Chris Urm-

logged nearly half a million test

tems, for example, vehicles can read road signs, infrared systems detect pedestrians, optical sensors scan the blind spots around the car and warn of unseen vehicles, distance meters activate emergency brakes in case of danger, and eye tracking cameras in the dashboard monitor the driver‘s

2/2015

»We will carefully bring this car on the road.« Chris Urmson, Google

Instrument display in a autonomous driving Audi. Photo: Audi AG

kilometers in autonomous opera-

ware that controls the car does not

its DNA. Where, if not here, would

tion with a fleet of upgraded Lexus

need a steering wheel because it

the Google car otherwise be will-

Series cars. The statistical figures on

has no hands.

ingly given priority?

the number of accidents in which these vehicles were involved should

According to Urmson, the techni-

convince skeptics. There were only

cians and engineers are now work-

eleven accidents. “Not once was the

ing to test the reactions of the new

self-driving car the cause of the ac-

vehicle. The designers have given

cident,” wrote Google’s Chris Urm-

it a cheeky, optimistic face. And

These developments are being ob-

son in an online post.

not without reason, the micro-car

served with curiosity from Germa-

is being allowed to drive only in

ny - some are even involved in it,

and around Mountain View in Sil-

since some German auto suppliers

icon Valley right now, a place with

are providing components for the

the need to be at the cutting-edge

Google car. Bosch, Continental and

of technical progress practically in

ZF Lenksysteme are three of them.

Software does not need a steering wheel, it has no hands

Germany contributes parts

According to reports, even BMW The next phase of the project will

has stretched its tentacles toward

now begin. Instead of converted

Silicon Valley. BMW Chief Devel-

serial cars, in which test drivers

opment Officer Herbert Diess, who

were already able to take their

joined Volkswagen in July, rated

hands off the wheel, the small

Google’s development quite posi-

Google car, deliberately designed

tively: “Google has huge reach and

to be cute, is taking to the streets.

therefore can push highly automat-

In this car, the engineers are sup-

ed driving further into external re-

posed to put their hands on the

ality.”

steering wheel only in an emergency. It is purely a precaution,

Audi is cooperating with the Chi-

because the production line mod-

nese IT company Baidu, the lead-

els of this little search engine car

ing search engine provider in China,

will have neither steering wheel nor pedals. What for? The soft-

Chris Urmson, head of Google‘s „Self-Driving Car Project „. Photo: Google

and Huawei, an electronics company. The average age of Audi drivers

2/2015

LIFE & BUSINESS

12 in China is 36; they are over 15 years

while Mercedes-Benz develops cars,

in front and keeps it constant. “Dis-

younger than the German clientele.

which have to work on the market

tronic plus has been available for

Thus it makes the cooperation of

in the present. But Mercedes-Benz

two years,” says Zeeb proudly and

the two companies a necessity. The

has experience in this area. The au-

explains, “This is the first semi-auto-

market and survival strategy in Chi-

tomation of vehicles already be-

mated system with longitudinal and

na is to move with the times and be

gan at Daimler in the 1920s, when a

now also lateral guidance, which

a pioneer.

switching device was designed for

takes control of the car almost com-

buses in the British Daimler Mo-

pletely.”

This progress is unifying the premi-

tor Company. The first automatic

um class German carmakers. They

transmission was introduced by an

do not want to pass up this automat-

American manufacturer in 1939.

ed driving opportunity. It can be as-

The aim was comfort while driving

sumed that when the time comes,

and making the driver’s job easier.

Experts like Zeeb distinguish dif-

Mercedes Benz S-Class, Audi A8 and

You may be wondering why you no

ferent levels of automation. They

BMW 7 Series will be the first to be

longer need your foot to accelerate

were defined by the German Fed-

fully automated. The three carmak-

or brake.

eral Highway Research Institute,

On the go

the federal research institute for

ers have been researching new and improved driver-assistance systems

Eberhard Zeeb, the head of driver

road systems. Currently, you can

for years.

assistance and chassis systems at

drive on German roads in a par-

Mercedes-Benz had no question in

tially automated car. In other

his mind about plans for automated

words, the system takes over con-

driving. Daimler has been research-

trol in specific applications, such

ing autonomous systems since the

as parking. The driver should al-

1990s, even before they had built

ways be able to re-take control.

Innovations close to the driver Customer requirements for vehi-

technical aids into vehicles, such as

cles in the here and now are at the

cruise control, ABS, stability control,

By 2020, highly automated driv-

forefront for the classic car compa-

and most recently distance control,

ing, in which the driver no longer

nies, more so than for Google. The IT

which Mercedes called Distronic. It

needs to monitor the system, as

giant develops future technologies,

checks the distance to the vehicle

opposed to a semi-automatic var-

The driver of the autonomous Freightliner Trucks can deal with other things while driving. Photo: Daimler AG

2/2015

A „Freightliner Truck Inspiration“ of Daimler during an autonomous driving in the state of Nevada. Photo: Daimler AG

iant, should be possible, and Goog-

surprises them however, is the so-

Pilot. This system keeps the truck

le’s plans will meet with those of

cial and media interest in the sub-

on the highway in its lane, avoid-

German carmakers. The driv-

ject and the public’s open-mind-

ing collisions, braking and driving

er will then be prompted by the

ed and positive viewpoint on the

around wide curves. It uses two

car with sufficient advance no-

subject.

cameras, GPS and radar systems.

tice to take over driving control only when necessary. The outgoing BMW development chief Herbert Diess considers it a duty of the

The driver can turn around ful-

With momentum on the market

ly with the seat. The vehicle will prompt the driver to take control again when necessary.

engineers: “The great leap that is yet to come is the transition from

Georg Stefan Hagemann, who is re-

In their quest to introduce such as-

partial to highly automated driv-

sponsible for pre-development of

sistance systems in Germany, the

ing. This is exactly what the cen-

models at Daimler Trucks, sees this

engineers have found an ally in the

tral task will be for researchers in

as a good chance to move the devel-

German Transport Minister Alex-

the coming years.” The next step

opment of automatic vehicles for-

ander Dobrindt, who has declared

would be doing factory produc-

ward. “The driving assistance sys-

a section of the A9 motorway as the

tion of a system that completely

tems are becoming increasingly

test track for Autonomous Systems.

controls the car, without the driv-

networked and more accurate. We

The innovation involves the road

er having to monitor the car, for

now need to maintain the momen-

being digitized so that the vehicle

example in situations such as a

tum, since the public are receiving

will be able to provide useful in-

traffic jam.

the topic so positively, and bring au-

formation on traffic conditions and

tonomous driving on the market.”

other factors. Using the test track,

Ultimately, none of those respon-

the German automotive industry

sible, either in Munich or Stutt-

In the US, Daimler is only a few

“can be a world leader” on the sub-

gart, are surprised by the rapid

tests away. They’re allowed to test

ject of digital cars, says the Min-

technological developments that

drive two autonomously driven

ister of Transport. In September,

promoted autonomous driving

“freightliners,” a truck brand of the

he plans to present key points for

and generated a buzz in the mass

Daimler family, on public roads

the further development of auton-

media. The technology is after all,

in the state of Nevada. Trucks are

omous driving. It will be interesting

their area of responsibility. What

steered by the so-called Highway

to find out what they are.

2/2015

LIFE & BUSINESS

Autonomous driving does not need any hands. Photo: Fotolia, RioPatuca Images

Structural core issues

then apply more processing power

ing must be handled by the powers-

for distinguishing dogs from hy-

that-be. The Vienna Convention on

Several Fraunhofer institutes are

drants at the roadside and to draw

Road Traffic of 1968 stipulated that

currently researching the optimal

the appropriate conclusions for on-

a driver must never give up control

networking of road and vehicle in

ward travel. It shouldn’t just slow

of his vehicle. This rule was adjust-

a joint project. Networking is one of

down for a dog.

ed by the United Nations in 2014. Sys-

the core issues on the road to highly

tems that take over the control of a

automated driving. An intelligent

No doubt, politicians must do their

vehicle have now been approved,

infrastructure can support the ve-

bit to help us on our way to autono-

as long as they can be overruled or

hicle, for example, if traffic lights

mous vehicles. The car industry can

turned off by the driver at any time.

pass on their status to the vehicle,

network the cars and the politicians

The driver, however, is not yet off

thus the sensors on the car won’t

can network the streets. Any legal

the hook. He must continue to mon-

need to handle that. The car can

issues regarding autonomous driv-

itor his vehicle at all times.

Milestones on the way to autonomous driving 1939: Oldsmobile presents the first automatic

developed in 1978. The first car to be equip-

transmission with two-speed automatic.

ped with ABS was the Ford Scorpio in 1985.

1958: Chrysler equips an Imperial-model se-

1999: Mercedes-Benz launches the first adap-

ries with an autopilot. This cruise cont-

tive cruise control. This enhancement of cru-

rol system has become widely known as

ise control includes the preceding vehicle

“Tempomat.” Tempomat is actually a brand

in the speed control calculation. Other com-

name of Mercedes-Benz for this technolo-

panies followed in the years thereafter.

gy, which the company introduced in 1962. 2013: Mercedes-Benz brings an adaptive cruise 1966: The anti-lock braking system (ABS) au-

control with lateral guide on the market. This hel-

tomates the brakes. Bosch holds the rights

ps the driver with steering and to stay in the lane.

to the term for this technique, which was

2/2015

15 What the different levels of automation mean Driver only: The driver controls the lon-

the system. The system is not capable of

gitudinal motion (acceleration / deceler-

bringing about a minimal risk

ation) and the lateral motion (steering)

state* for each starting point.

of the vehicle fully and permanently. Fully automated: The system takes conAssisted: The driver must control either the

trol of longitudinal and lateral mo-

lateral or the longitudinal movement per-

tion fully for a defined application.

manently. The other driving task is per-

• The driver does not have to monitor the system.

formed within certain limits by the system.

• Before ending the specific application, the sys-

• The driver must monitor the sys-

tem prompts the driver to take over the driv-

tem permanently.

ing task with sufficient time to spare.

• The driver must always be ready for

• If that does not occur, the system re-

complete takeover of the vehicle.

turns to the minimal risk status.* • All system boundaries are recognized by the

Partly automated: the system assumes lon-

system, the system is able to return to min-

gitudinal and lateral control for a peri-

imal system risk state* in each situation.

od of time and / or in specific situations. • The driver must monitor the sys-

* Minimal Risk State: This could mean, for ex-

tem permanently.

ample, that the vehicle drives to the edge of the

• The driver must always be ready for

road, stops, and turns on the hazard lights.

complete takeover of the vehicle. Source: German Federal Highway Research Institute

Highly automated: the system assumes longitudinal and lateral control for a period of time in specific situations. • The driver does not have to monitor the system. • If required, the driver is prompted to take over the task of driving with sufficient advance notice. • All system boundaries are recognized by

Hopes and dreams

ness. The reasons for this are that

So it is still not the best idea to

the body perceives motion, while

drive home in your own car after

Many dreams are connected with

the eyes are focused on a book or

a visit to the beer garden. Some

autonomous driving, whether it

a Smartphone. Furthermore, the

problems can obviously not be

is the significant reduction of ac-

change of direction of movement

solved by autonomous driving.

cidents, saving of fuel, better uti-

is not predictable.

Text: Piet Felber

lization of vehicle fleets, the reduction of transport costs or the opportunity to drive home in your own car even though you’ve had a few drinks. However, researchers at the University of Michigan have found that autonomous driving increas-

»Driving assistance systems are becoming increasingly networked and more accurate.« Georg Stefan Hagemann, Daimler AG

es the likelihood of motion sick-

2/2015

â&#x20AC;&#x153;Autonomous driving will require more cleanroomsâ&#x20AC;?

LIFE & BUSINESS

Christian Ernst, an expert in cleanroom manufacturing and use in the automotive industry.

Cleanroom Magazine: When we im-

Cleanroom Magazine: What re-

agine car manufacturing, we usual-

quirements must cleanrooms spe-

ly think of metalwork and welding

cifically meet in the car industry?

robots, but not cleanrooms. What kind of cleanroom is actually used

Christian Ernst: Clean production

in the automotive industry?

areas must especially ensure high throughput and allow a range of

Christian Ernst: In the car industry, more and more cleanrooms are being installed and used according to their barrier function and operation of cleanroom practice. The mission

About the Person: Christian Ernst is a researcher of clean production design at the Stutt-

variants. Admittedly, flexible contract manufacturing and short

garter Fraunhofer-Institute for Manufacturing

product life cycles are potential

Engineering and Automation (IPA) in the

difficulties in minimizing harm-

Department of Cleanroom Manufacturing.

ful impurities. We are talking

is to curb the introduction of par-

about manufacturing, where ten

ticles above the critical 50-micron

for example, has already been a

cents could affect competitiveness.

mark. In certain cases, a clean work-

big challenge here.

Additionally, there are production

bench or clean air zone protects the

parts and components that do not

product, such as a packaging island

Cleanroom Magazine: In addition

themselves have any function-

for fuel lines after they have been

to the labs, are there also applica-

al cleanliness requirements, but

cleaned.

tions for cleanrooms in produc-

must be processed together with

tion?

sensitive components and prod-

Cleanroom Magazine: And in which

ucts. In the supplier industry, a go

areas are real cleanrooms used in

Christian Ernst: Yes, classical pro-

od understanding of contamina-

the car industry?

duction technology cleanroom

tion and clean technology is only

applications include the paint-

now being developed.

Christian Ernst: A relative-

ing of car bodies or the produc-

ly young, but constantly grow-

tion of headlights. Additional-

Cleanroom Magazine: Where are

ing, application is pure laborato-

ly, there are a variety of interior

further applications for clean-

ry space for testing the technical

surfaces that must look absolute-

rooms emerging in the car indus-

cleanliness of automotive parts.

ly flawless when handed over to

try?

In research and development,

the proud owners of a new vehi-

two aspects primarily play the

cle. To ensure technical function,

Christian Ernst: Autonomous

most important role: what level

controlled areas are also required

driving means more sensors and

of cleanliness is required for pro-

in the production of high-perfor-

actuators, which in turn require

duction of my future product and

mance batteries or fuel cells. Pro-

even greater reliability, especial-

which contaminants have to be

tecting products from particles

ly in the safety-related systems.

eliminated in order to maintain

that could impede their function

There is no doubt that more clean-

the functionality of a new and

also extends over a wide range of

room areas will be needed for

technologically complex produc-

security-related elements such as

their production.

tion process. The multilayer piezo

ABS, steering, control units, and

technology for injection systems,

sensors.

2/2015

DO YOU SPEAK CLEANROOMS?

sue s I e n o z n a e l K WCE SPEA

! S M O O R N A E L C

12 dline: August Editorial Dea adline: September 07 De Advertising

More information? Editor in Chief | Roy Fox Tel.: +49 (0) 6201 606714 | roy.fox@wiley.com Advertising | Roland Thomé Tel.: +49 (0) 6201 606757 | roland.thome@wiley.com ä www.gitverlag.com/go/reinraumtechnik

2/2015

When fabrics think ahead

LIFE & BUSINESS

Smart textiles change medicine, architecture, fashion and auto industries.

Miniaturized electronic components from the cleanroom provide textiles with intelligent functions. The clever fabrics monitor body functions, send distress signals, lead fire fighters through smoke and even allow unprecedented applications in cars and buildings. The company Luna Sleep is bring-

Conductive fibres

ing the Internet to bed. The US

and communicate with each other, people and the environment.” Possible applications could be, according to the researcher, seat belts with integrated microphones that allow hands-free systems, sports shirts that monitor the heart rate, or even intelligent fire-fighters’

start-up has developed a sheet

Modern textiles have previously im-

suits, which indicate the right

that can communicate via wire-

pressed us with fascinating func-

path on the fire-fighters’ visors in

less with all smart home solutions.

tions like waterproofing, breathabil-

smoke-filled buildings.

When the owner goes to sleep, the

ity, fire resistance, and reflectivity.

mattress cover turns off the light

Now, the spectrum of their proper-

and turns down the heat. Earli-

ties will be expanded into a new di-

er, the clever sheets had warmed

mension by miniaturized electron-

themselves to a pleasant sleep-

ic high-tech components, many of

Technical textiles are conquering

ing temperature that the owner

which are produced in clean rooms.

more and more applications, re-

had set via a smart phone app. At

Washable chips, sensors, actuators,

placing conventional materials.

Knitted shoes

Examples include artificial arteries in medical techniques, textile

»Textiles are becoming smart. They can measure, verify, and monitor.« Ivana Cujic, Institute for Textile Techniques at the RWTH Aachen

reinforcement materials in concrete or fibre composites in the automotive industry. Even in sports, technical textiles prevail. Mario Götze scored the winning goal in the 2014 World Cup with a “knitted” shoe. With the widespread use of tech-

night, the sheet uses numerous

and conductive fibres breathe life

nical textiles, more and more new

sensors to monitor the heart rate,

into the brain of the simple fabric.

manufacturing processes are also arising. “The German industry is

breathing and sleep cycle of the owner. Thus, the sheet can, with-

“Textiles are becoming smart,”

considered – thanks to its good net-

in a fixed time window, set off the

says Ivana Cujic from the Insti-

working with German research,

alarm clock during a light sleep

tute for Textile Techniques at the

which is unparalleled worldwide

phase, instead of tearing the own-

Rhine-Westphalia Technical Uni-

– to be the world’s technological

er from a deep sleep.

versity (RWTH) in Aachen, west-

market leader,” says Jürgen Grebe,

ern Germany. “They can measure,

analyst with Commerzbank and

verify, and monitor, produce their

author of the latest industry re-

own energy, give off substances

port, “Technical Textiles”.

2/2015

Rio de Janeiro, Brazil, Maracana Stadium: With a knitted footwear from an innovative material Mario Götze scored the winning goal in the final of the football World Cup on July 13, 2014 against Argentina. Photo: Ian MacNicol, Getty Images

New solutions for cars Anyone who looks at the solutions

and design of textile support mate-

May 2015 in Frankfurt, showcased

rials now no longer have any limits,”

textile reinforced concrete, proving

says project manager Evelyn Lampe.

that textiles are also suitable as a

and vision of the textiles industry will be surprised by the variety of functionalized fibres. The wealth

building material. Fibres made of

Textile construction

of materials, coatings, compositions

glass or carbon replace the steel in the concrete. The advantage: textile reinforcement will not rust, will

and properties is large. According

The international biannual trade

last longer and will reduce renova-

to Commerzbank, completely new

fair, Techtextil, which was held in

tion costs. Since 2014, textile rein-

products could arise in a few years

forced concrete has been officially

such as textile displays, textiles with

approved. “A milestone,” says Roy

colour-change and self-cleaning

Thyroff, Managing Director of the

functions, energy-saving surfaces

Tudalit Textile Reinforced Con-

and self-healing structures.

crete Association in Dresden, Saxony. Other approvals are already in

Such innovations are just as in-

the pipeline: currently, the German

teresting as the novel textile sur-

Institute for Building Technology is

face electrodes that the Hochschule

evaluating completely prefabricat-

Niederrhein in Krefeld, western

ed garages, sandwich facades, and

Germany, is working on for the car

even pedestrian bridges – approval

industry. This could, in the future,

expected by 2016.

allow roof and seats to glow softly or heat seats, carpeting and door panel surfaces. “The technological leap for the automobile industry is remarkable, because construction

Architects see another area of the Completely new functions: Smart textiles can also light up. Photo: Messe Frankfurt Exhibition GmbH / Jean-Luc Valentin

future in textile-based sensors. Through them, areas of buildings could, in the future, have additional,

2/2015

20 intelligent functions such as lighting, heating, measuring of moisture content and stability, or even fire, smoke, or flooding alarms.

Market worth billions

Textile-based sensors can illuminate buildings, heat, measure moisture, and warn against fire, smoke, or flooding.

According to Commerzbank, the world market for technical tex-

LIFE & BUSINESS

tiles is currently more than 130 billion US dollars, and will grow to

2020. The analysts see the greatest

Professor Stefan Jockenhรถvel holds

up to 160 billion US dollar by 2018.

growth in protective and military

a professorship in medicine and

The most important customers

clothing, in sports and fitness ap-

is director of the Institute of Tex-

come from the automotive, con-

parel, as well as in medical tech-

tile Technology in Aachen. In this

struction, and geotextile indus-

nology.

so-called bridge professorship, he

tries. Eco-textiles, nonwovens, and

works with others on textile-sup-

the hygiene sector are also gaining

ported implants and functional in-

importance. According to a study

Use in medicine

tegrated clothing to monitor health parameters. The latter could, for ex-

by the Danish Ohmatext ApS, the market for smart textiles was 289.5

Especially in medicine, smart tex-

ample, reduce the amount of large-

million US dollars in 2012 and will

tiles open up fascinating possibil-

scale equipment in intensive care

grow to 1.5 billion US dollars by

ities.

units and keep the wiring of the pa-

Let there be light: The miniaturization of LED light sources makes this interesting for the production of light emitting textiles. Photo: Ohmatex

2/2015

21 Conceptual confusion. What does … mean? Smart Textiles: The term refers to textiles

Wearables: This term means electronic devic-

that have the ability to respond to mechani-

es that are small enough to be worn on the body.

cal, electrical, thermal, and chemical stimuli.

Interactive Textiles: This is portable technology integrated into a garment or controlled

SFIT: These initials stand for Smart

by an integrated control panel or buttons.

Fabrics and Interactive Textiles; they E-Textiles: This refers to textiles whose fi-

are also defined as smart textiles.

bres make electronic properties available.

tient to a minimum, according to

waves) “just by the way”. At the Tex-

Research Institute Thuringia-Vogt-

Jockenhövel’s opinion. The experts

tile Research Institute Thuring-

land, researchers invented, among

see applications in the home care ar-

ia-Vogtland in Greiz, scientists have

other things, gloves with built-

ea also: sensors in mattresses or in

developed a smart textile glove that

in heating. The company Weara-

the clothing of a patient could mon-

supports the treatment of stroke pa-

ble Life Science has a suit in their

itor bodily functions and quickly

tients through reorganization of the

sports and lifestyle sector with elec-

communicate with doctors in an

sensorimotor areas of the brain. For

trodes for targeted muscle stimula-

emergency.

this, the researchers received an in-

tion. And the fashion label Tommy

novation award.

Hilfiger offers a jacket whose wo-

Baseball cap measures brainwaves

ven solar panels charge your phone.

Uses outside of medicine

At the Aachen Institute, a baseball

Scientists at the Hochschule Niederrhein developed a jacket of a different kind. It is tear and cut resistant and can protect taxi and bus

cap is available with integrated elec-

There are also more and more

drivers from knife attacks. Textile

trodes of silver-coated polyamide

smart textile applications outside

researcher Eva Lempe says, “We

yarn. This can be part of everyday

of medicine. Interactive Wear AG

want to install an additional lay-

life with a permanent record of EEG

developed a snowboarding jacket

er with a sensor that sends a signal

(electroencephalography, a meth-

with built-in controls for mp3 play-

during an attack so that an emer-

od for measuring electrical brain

er and mobile phone. At the Textile

gency call is triggered.”

A clean room arises from the mind www.cleanroom-academy.com ACADEMY – Training courses, seminars, coaching CLEANROOM EXPERTS DAYS – conferences KNOWLEDGE BASE – Trends and Innovations COMPETENCE CENTER – Cleanroom knowledge at your fingertips

2/2015

LIFE & BUSINESS

Miniaturized electronic components and conductive fibres breathe life into the brain of common fabrics. Photo: Ohmatex

Solutions for industry

lished an RFID-based textile man-

that overalls would tell a person

agement system. It ensures com-

if they fitted properly, if they had

For industry, there are also inter-

plete control of all textiles used.

been worn before, and when the

esting applications. Wearable RFID

“We can scan the contents of an

next training session is necessary.”

technology makes it possible to de-

entire container in a second,” says

In addition, a smart overall could

termine, for example, if an employ-

Erik Otten, Sales & Marketing Man-

trigger an alarm if an employee is

ee is wearing prescribed protective

ager at Berendsen. This is efficient

sweating too much. Another idea

clothing. The RFID technology has

and saves handling when custom-

would be a mirror that commu-

a transceiver system that uses radio

ers pick up their things or when

nicates with the cleanroom over-

waves to locate and automatically

goods are being delivered to their

alls, and checks if the overalls are

identify objects without touching

own laundry facilities. Another ad-

suitable, for example, for a clean-

them. Such solutions are interesting,

vantage of the system is that it reli-

room class 6.

for example, for access control in

ably prevents a used coverall being

cleanrooms. It is quite possible that

reintroduced into the production.

smart cleanrooms coveralls will one

“With this system, we could even

day measure the body temperature

monitor how long a mop has al-

of the wearer and send the result to

ready been in use in the cleanroom

the cleanroom airlock. When it’s de-

and when it is time for a change,”

To make textiles smart, manufac-

termined that the person concerned

says Otten.

turers of electronic components as

Requirements for electronics

has a fever, the cleanroom door au-

well as wire and connection tech-

tomatically remains closed in order

nologies must cope with two chal-

to keep germs out of the cleanroom.

Radio control for the mop

Cleanroom clothing communication

lenges. Since clothing, unlike electronic components, is flexible, it is important to ensure that electrical

The managing director of the

contacts will not tear due to move-

Cleanroom Academy in Leipzig,

ment. Secondly, functional textiles

Frank Duvernell, imagines even

need to be washable at 90 degrees

The Berendsen Group, a leading

more very different applications

Celsius, without the sensors and

textile service company, has estab-

for the cleanroom. “One vision is

electronics being affected.

2/2015

Energized: Washable and stretchable wire and connection technology, the spectrum of technical textiles properties is expanding into a new dimension. Photo: Ohmatex

These requirements are fulfilled

sors, miniaturized connection tech-

large, new market, not only to tex-

with flexible and stretchable sub-

nologies, energy-efficient commu-

tile manufacturers, but also to those

strates made of silicone, polyure-

nication electronics and powerful

who manufacture microsystems

thane and polyimide, and textiles

batteries, which can be recharged

technology for use in cleanrooms.

that can accommodate a large area

wirelessly, are also available. Smart

of electronic assemblies. Tiny sen-

textiles and wearables open up a

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2/2015

Digital Scalpels

LIFE & BUSINESS

During surgery, doctors are increasingly supported or even replaced by intelligent, high-tech systems.

The surgical workplace of the future has hardly anything in common with the traditional operating room. Visualization systems, navigation, and robotics open up completely new opportunities to the surgeon and enhance the quality and safety of operations. The biggest leap in global competition for the operating room of the

Operating in areas that are not visible

future happened in Leipzig, Saxo-

digital scalpel evens out slight hand tremors automatically, thus allowing safe surgery, even in the narrowest spaces. On nine displays, the surgeon has 40 data sources with current images available from inside the body, 3D computer tomography images, the vital functions of the patient, their

ny. This is where the Acqua Clin-

“In the past, we had to open the skull

ic put the latest model of the so-

for brain surgery. Today we use body

called surgical deck into operation,

orifices such as the nose for intro-

in March 2014. The managing direc-

ducing instruments. In other words,

tor and Chief of Surgery, Prof. Dr.

we operate in the invisible range,”

Gero Strauss, called it a high-tech

explains Professor Strauss. ‘Surgery

workplace for surgeons and anaes-

without visibility’ is made possi-

These numerous visualization op-

thetists.

ble through surgical instruments

tions increase the safety of sur-

which are equipped with naviga-

gery enormously. For example: If

tion technology, distance detectors,

the surgeon wants to go through

and systems for transmitting imag-

the nasal cavity to the brain, he

es from inside the body. “The optical

must sever a layer of flesh in or-

resolution of our endoscopes is so

der to advance through the bone

high that we can magnify the tiniest

into the brain inside the skull. The

structures; so high that you can see

problem with this is that a hid-

the individual red blood cells flow-

den artery runs through the lay-

ing,” says the hospital director. This

er of flesh and supplies the brain

magnification is extremely helpful

with oxygen. “In the past, sur-

for detecting, for example, exact tu-

geons needed a lot of experience

mour boundaries.

and a bit of courage to cut here.

Professor Gero Strauss, Acqua Klinik Leipzig

medical records, and much more.

Still not possible five years ago

If he touched the artery at all, he This operating system is unique

A micro manipulator ensures a

wouldn’t be able to save the pa-

steady hand while cutting. This

tient,“ says Gero Strauss.

worldwide and looks like the command centre of a spaceship. On the walls hang huge HD monitors, the operating table is surrounded by touch screens and by the surgeon’s feet are ten foot pedals, with which he can switch back and forth between different functions and views.

2/2015

»Such a thing was not possible five years ago.« Professor Gero Strauss, Acqua Klinik Leipzig

Fotos: Audi AG

Looking into the next generation operating theater: The surgical workplace of the future has already become reality in the Leipzig Acqua clinic. Photo: Acqua Clinic

That can no longer happen with the surgical deck. A blue filter, which is

Increasing Demand by 2020

placed over the real image, makes

ed by the German Medical Technology Association in Berlin, the world market for such products

the artery visible. In addition, the

Such forward-looking technolo-

was around 220 billion Euros in

scalpel starts to hum once it touch-

gies are the result of a high level

2012. The US has by far the largest

es something “wrong” and, on top of

of innovation in medical technolo-

share with 90 billion Euros. The

that, a display accurately shows the

gy companies on the one hand and

second largest medtech market in

distance between the scalpel and the

the strong global demand for their

the world is Japan, with around 25

artery. “Such a thing was not pos-

solutions on the other. According

billion Euros. Germany’s market is

sible five years ago,” says Professor

to the current “Industry Report on

in third place with around 22 bil-

Strauss.

Medical Technologies 2015,” creat-

lion Euros, and is almost twice the

2/2015

26 size of France and three times the

is primarily for innovations with

for experiments. Among the cur-

size of Great Britain. According to

higher quality and greater product

rent research projects at the compe-

a study by the Hamburg Institute

variety. The companies between the

tence centre are the development of

of International Economics (HW-

North Sea and the foothills of the

a networked and automated inter-

WI), by 2020 the demand for medi-

Alps have a lot to offer, thanks to

vention space with a lightweight ro-

cal technology will increase annual-

their close links with the German

bot, which includes instrument sys-

ly in developing countries between

research community, which is very

tems for diagnostic and therapeutic

nine and 16 per cent on average. For

advanced.

processes. This robot can be steered

industrialized countries, the study

to fully automated injection sites,

indicates an annual growth of be-

In Mannheim, for example, a start-

for example, to introduce a biopsy

tween three and four per cent.

up and competence centre for med-

needle for tissue sampling.

LIFE & BUSINESS

ical technology was opened on the

Experimental Intervention Area

campus of the University Medical Centre in March 2015. In its experimental operating room, with endos-

Surgeon operated with Robotic Arms

copy towers, operating tables, and German medical technology com-

a high-tech X-ray imaging system,

Researchers at the German Aer-

panies can profit from this strong

companies can try out new systems

ospace Centre (DLR) in Bavarian

growth, according to the authors

and check their ideas in a clinical

Oberpfaffenhofen are going a step

of the HWWI study. The demand

setting. Body replicas are available

further. They are currently develop-

Medical Technology in Autumn 2015 MEDICA 2015: Dusseldorf, 16.11.15 through 19.11.15 This year, 4,800 exhibitors from more than 60 countries are again expected to attend Medica in Düsseldorf. The World Forum for Medicine presents new products, services, and procedures for inpatient and outpatient care. No other event in the world offers anything even close to this wealth of innovations. A key strength of Medica is that it presents both solutions for individual medical disciplines as well as the complete workflow of patient care COMPAMED 2015: Dusseldorf, 16.11.15 through 19.11.15 With more than 700 exhibitors, the world’s leading trade fair for medical technology will take place from November 16th through 19th, four days long and, for the first time, parallel to the world’s largest medical trade fair, Medica 2015 in Düsseldorf. On display are solutions for the various requirements of medical technology providers, from new materials, components, intermediate products, packaging and services through to complete contract manufacturing. Microsystem technology solutions for mobile diagnostic, monitoring, and therapy systems are particularly popular this year. BIOTECHNICA 2015: Hannover, October 6th through 8th Biotechnica in Hannover is Europe’s No. 1 in the industry for biotechnology, life sciences, and lab technology. Biotechnica is the only trade fair that provides the entire value chain of biotechnology, ranging from basic research to finish products. The exhibition, with more than 600 exhibitors from 28 countries, is a meeting place for international leaders, biotech clusters, and research institutes from all over Europe. LABVOLUTION 2015: Hannover, October 6th through 8th The Labvolution exhibition is a platform for the entire range of lab equipment. It takes place parallel to Biotechnica. Its topic is the whole world of laboratory equipment for research, analysis, production and training labs. Here, research meets industry. The laboratory engineering fair is also the scene of a world premiere: the special exhibition “smartLAB – The intelligent laboratory of the future“, which presents a vision of the intelligent lab of tomorrow.

2/2015

27 ing interactive robotic arms, which are used by surgeons and provide haptic feedback. This telesurgery system should be usable in the operating room in a few years. The surgeon will be able to control several robotic arms through two input devices. One of the arms carries an endoscopic camera and transmits images of the patient to a 3D display. The other arms are equipped with instruments that have sensors. These allow the surgeon to haptically feel that he is cutting into the tissue. Robotic arms for surgery are also the focus of the world’s largest medical trade fair, “Medica 2015”. It takes places from November 16th through 19th in Düsseldorf in western Germany and is an event devoted to the latest surgical techniques.

Virtual Assistant feels Empathy Equally amazing: The medical technology of tomorrow will not only make haptic feedback possible, but will also be capable of empathetic responses to the surgical team. The Karlsruhe Institute of Technology and the Fraunhofer Institute of Optronics, System Technologies, and Image Exploitation based in the same location, together with the University of Heidelberg have been leading a project on this since March 2015. The

Modern operating rooms are high-tech equipment pools. Photo: Messe Duesseldorf / ctillmann

three southwest German institutions want to create a virtual assistant that

asked. The virtual assistant observes

tance system to activate when need-

supports the individual members of

the operation with sharpened senses,

ed. It can then offer alternative pro-

the surgical team in accordance with

but in attentive standby mode, and

cesses and assist the team with them.

their respective responsibilities in

intervenes only when there are de-

situations that are not routine.

viations from the routine. This ensures safety, especially with rare in-

Big Data in the Operating Room

What is visionary about the project,

terventions and unforeseen events.

named “KonsensOP”, is that it pro-

Through a novel combination of sen-

vides proactive and empathetic sup-

sory systems that detect the emotions

Smart data processing plays an in-

port for the surgeon and team mem-

of the surgical team members, the

creasingly important role in medi-

bers if needed and without being

researchers want to allow the assis-

cal technology. That is why the Fed-

2/2015

28 eral Ministry of Economic Affairs has

which helps by making the clinical

Thanks to the Bremen scientists, sur-

set up the technology program “Smart

processes more structured and net-

geons will one day get recorded 3-di-

Data”. It promotes 13 projects which

worked,” says Norbert Hansen, Senior

mensional information when they

develop solutions for handling large

Project Manager at Karl Storz.

are looking through a microscope

volumes of data. One of these is the

during a brain tumour surgery. Ad-

project InnOPlan, which is run, with

ditionally, the interactive systems al-

five partners, by Karl Storz GmbH & Co KG in Baden-Württemberg Tut-

Without keyboard and mouse

tlingen. The aim is to optimize the

for the procedure, while controlling the hardware using gestures or lan-

processes in and around the oper-

The University of Bremen is trying to

guage. Keyboard and mouse aren’t

ating room through intelligent data

optimize the tailor-made support of

necessary.

processing.

surgeons even further by converting data into three-dimensional infor-

LIFE & BUSINESS

low the surgeon to use both hands

Telemedicine on the rise

Among other things, the research

mation. “We got into the question of

focuses on how medical devices can

how and when the information can

be intelligent data suppliers, how to

be optimally provided as image da-

Another result of digitization is

sift out useful information from un-

ta during an on-going surgery,“ says

that innovations in the operating

structured data volumes and how

Project Manager Ron Kikinis. The

room of the future can also im-

this can be networked with process-

computer science professor at the

prove the care of patients outside

es inside and outside of the operating

University of Bremen is also profes-

of the hospital. Doctors can avoid

room. “With the InnOPlan project,

sor of Radiology at Harvard Medical

critical situations in the treatment

we are pursuing the goal of expand-

School in Boston and director of the

of severely ill patients in intensive

ing already very powerful medical

Institute of Fraunhofer MEVIS. He is

care units by virtual consultations

devices so that they not only fulfil

considered a pioneer of computer-as-

with specialist peers. Projects in the

their technical function, but that ad-

sisted medicine and founded the Sur-

US have already shown this to be

ditional data intelligence is created,

gical Planning Laboratory in Boston.

effective. A pioneer in Germany is

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innovativ – kompetent – kundenspezifisch vali.sys gmbh hofstrasse 94 ch-8620 wetzikon telefon: fax: e-mail: internet:

2/2015

+41 43 495 92 50 +41 43 495 92 60 info@valisys.ch www.valisys.ch

29 the University Clinic in Aachen, in the west of Germany. “With telemedicine, we are on the threshold of a new era in the ICU,” says Professor Thea Koch, President of the German Society of Anaesthesiology and Intensive Care Medicine. Patients in smaller hospitals stand to benefit from this. These institutions have the advantage of being close to home and family but cannot yet provide the quality of care that a teaching hospital can in an emergency. Therefore, the 24-hour presence of an experienced specialist with an additional qualification in intensive care is necessary. In the future, this problem will be solved by telemedicine. How this works can be seen in Germany’s first pilot project TIM (Telematics in Intensive Care). The Aachen University Hospital is connected via an encrypted data line to two hospitals in the region, so the doctors can rely on an experienced ICO expert in times of crisis. Through real-time transmission of the patient’s vitals, the experts support their local colleagues when making important decisions in a matter of seconds.

Fewer Deaths and Lower Costs Telemedicine is still in its infancy. Its success in intensive care,

Navigated robotic placement of a needle, demonstrated on a replica of a human body. Photo: Fraunhofer IPA

however, is undisputed. International studies have shown that

yielded even remotely similarly

tele-intensive care measures re-

impressive medical and economic

duce the mortality rate significant-

results. Now, we must just take the

ly and shorten the hospitalization

right course of action.”

of patients. This reduces the cost of treatment. “The data clearly shows the potential that lies in tele-intensive care,” sums up Professor Thea Koch. “No other drug or technical innovation of the past 20 years has

2/2015

On the road with...

LIFE & BUSINESS

Dietmar Pfennig, Pfennig Reinigungstechnik GmbH

Dietmar Pfennig is CEO of Pfennig Reinigungstechnik GmbH in the southgerman Town Durach. The enterprise develops, manufactures and sells tools for cleaning of buildings. Additional there is a wide range of products for the cleaning of cleanrooms in the pharmaceutical, cosmetic and chemical industries as well as for the cleaning of production areas of the semiconductor industry.

How often do you travel? Two to

What is your favorite way to travel?

What factors are most important to

three times a week on average, to

By plane – preferably flying the

you when you’re traveling? Going

do training and consultations with

plane myself. I like to fly very much

as fast as I possibly can… (laughs).

our customers. Lectures on the sub-

and have the good fortune to have

Naturally, clear roads are impor-

ject of manual cleaning equipment

an airfield close to home where one

tant because punctuality and re-

for the cleaning of cleanrooms are

can rent planes. For business, how-

liability are necessary for good

also on the schedule.

ever, I travel more by car.

work.

2/2015

31 What items do you always bring with

What’s the best way for you to un-

power for the better; that is, to con-

you? Sunglasses, good audio books

wind? If I’m on the road, I read a lot

tinue to strengthen the company,

and the latest issue of Der Spiegel.

or listen to my favorite songs. Sitting

my colleagues and my family. And

in the hotel in the evenings and lis-

with our foundation, which pro-

What kind of music do you listen to on

tening to relaxing music or read-

motes greater access to education

trips? I listen to a lot of audio books,

ing is pure relaxation for me. And

for children, we can also do a lot of

and I like soul music from the 60s

on the weekends, I spend time with

good along the way.

and 70s.

my family.

What countries and regions do you

Which places do you prefer and why?

visit most frequently in your trav-

Italy, because of the landscape, the

els? The entire length and breadth

weather, the food, the wine, the peo-

of Germany; Switzerland, Italy, the

ple…Italy is great.

United Kingdom and also Austria. If you had the unlimited power to Can you get away from daily busi-

change anything, what would be

ness activities if you’re traveling? Yes!

the first thing you’d change? I’d put

In the beginning it was more diffi-

a ban on trucks passing each oth-

cult, but now I can manage that very

er on two-lane highways… (laughs).

well. I have a great team at PPS and

No, I’ll never have the power to

can rely on them to keep the busi-

make large changes. I can only try

ness going.

to change the things that are in my

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2/2015

Science & Technology

SCIENCE & TECHNOLOGY

Technology in brief

New surgical centre for the University of Munich

Computer chip made of wood

High-performance operating rooms |

Green Electronics | Researchers at the

sion process, a natural, fully functional

dogenous cells colonize the vascular prosthesis and convert it into the body‘s own tissue. At the end of the conver-

A new high-performance surgical cen-

University of Wisconsin-Madison,

blood vessel is restored. The new meth-

tre has been established on the Univer-

USA, recently introduced a computer

od has already been very successful in

sity Hospital of Munich Grosshadern

chip made from biodegradable cellu-

an experiment on laboratory animals.

campus after six years of construction.

lose. The chip consists mostly of wood

In addition to the surgical peripher-

and is supposed to reduce the environ-

als such as sterile corridors, induc-

mental impact of electronic waste. The

tion rooms and recovery rooms, sup-

researchers replaced the commonly

ply facilities and offices, there are 32

used substrate in chips with nanofi-

high-performance operating rooms,

brillar cellulose. This is a flexible and

each of which specializes in one field.

biodegradable material made of wood

This includes, for example, the fol-

fibres. According to the researchers,

lowing faculties: trauma, gynaecolo-

these chips can, in the future, easily

gy, urology, cardiothoracic and vascu-

decompose in the forest using mush-

lar surgery, next door to each other, so

rooms, thanks to this substrate. The cel-

Synthesis of biodegradable polymers in the

to speak. The new building also has an

lulosic material is as safe as bio-ferti-

laboratory of the Technical University of Vienna.

outpatient surgical centre with four

lizers, unlike today‘s petroleum-based

more operating rooms, an emergen-

carrier materials.

cy room and a sterilization unit. Bavarian Lindner Clean Room Technology GmbH was a key contributor to the interior design. The new building has

New material for the production of artificial blood vessels

Photo: Technical University of Vienna, Austria

High-tech machine for cleanroom goggles Clear vision | Initial CleanRooms is now expanding its range of servic-

cost nearly 196 million Euros, making the Grosshadern campus one of the

Polyurethane blood vessels | The Tech-

es in the field of cleanroom textiles

most efficient and modern in Europe.

nical University of Vienna and the

with a new high-tech goggle washer

Medical University of Vienna, Austria

at Reutlingen (Baden-Württemberg),

have developed artificial blood vessels

Germany. Upon customer request,

that are broken down by the body over

Initial CleanRooms can now decon-

time and replaced with its own tis-

taminate and sterilize goggles for use

sue. These artificial vessels are made

in cleanrooms. Any microorganisms

of newly developed thermoplastic pol-

that may be on the goggles are large-

yurethanes. Its wall is very similar to

ly eliminated during the washing pro-

natural blood vessels. The polymer fab-

cess. The well-tested cleanroom wash-

ric is slightly porous. Thus some blood

er for goggles ensures reproducible

will initially seep through, which pro-

washing results every time through

motes the migration of endogenous

standardized processes, as opposed to

cells. Gradually, more and more en-

the usual manual spraying of goggles.

View into the new surgical centre in Munich. Photo: Lindner Group

2/2015

33 Moreover, the goggles remain free of

supposed to heal tuberculosis and

distance measurements even under

scratches and milky cloudiness. This

cancer, and help against morning

extreme production conditions such

new high-tech washer can also wash

sickness. Kumdang-2 was developed

as heat, smoke or fog, is the focus of

rubber shoes and cleanroom clogs.

by the North Korean pharmaceutical

research. Furthermore, the research

company, Pugang. In addition to gin-

is aimed at, in the future, being able

seng extracts the drug is supposed to

to control contamination of all kinds

contain rare earth elements. Accord-

on surfaces during the production

ing to KCNA the miracle vaccine has

process by means of laser sensors.

been in the works since 1989. KCNA continues to report about revolutionary developments in North Korea, but hard evidence or relevant research results have not been supplied.

Sensors for Industrial Applications 4.0 The new goggle washer during changing of the wash basket. Photo: Rentokil Initial

North Korea has a miracle cure for MERS

Cooperation project | The development of low cost sensor systems for the control and protection of production lines is the goal of a joint project between the Freiburg Fraun-

Vaccine | While South Korea battles

hofer IAF (Institute for Applied

the largest outbreak of MERS (MERS

Solid State Physics) and the DH-

belongs to the group of coronavirus-

WB Loerrach (“Duale Hochschule

es like the SARS virus and many cold

Baden-Württemberg,” Baden-Wurt-

viruses) outside of the Arabian Pen-

temberg Cooperative State Universi-

insula, North Korea claims to have

ty). The two southwest German in-

developed a wonder vaccine against

stitutions want to support especially

MERS, Ebola and HIV. According to

small and medium sized enterprises

the official news agency Korean Cen-

on the way to industry 4.0 with these

tral News Agency, KCNA, the sub-

new sensors. The radar sensor sys-

stance, called Kumdang-2, is also

tem, which should provide reliable

DHBW President Prof. Reinhold R. Geilsdörfer (middle) informs Baden-Württemberg’s Minister of Economic Affairs, Nils Schmidt (left) about crystal growth methods for radar sensors. Photo: Fraunhofer IAF

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24.06.15 14:32

2/2015

No more white monotony

SCIENCE & TECHNOLOGY

Colour and design in cleanrooms improve wellbeing and product quality

Cleanrooms that are ergonomically designed and have attractive colours improve concentration, reduce reject rates and sick days. A beautifully designed cleanroom is hardly more expensive than a white one.

room is more beautifully designed than the cleanroom” adds Frank Duvernell. Unfortunately, colour and design are often disregarded in pure production areas for cost

“If you ask five people about the col-

ality have priority, whereas archi-

reasons. However, these expenses

our and the design of cleanrooms

tectural aesthetics come second.

are often lower than expected: “We

you will receive five different opin-

“This then often results in the typ-

have conducted a survey choosing

ions, but the compromise is al-

ical, white cleanroom with glass

a colour design for the wall pan-

ways white,” says Frank Duvernell,

and stainless steel,” says Duvernell.

els, twist outlets, cleanroom cloth-

the CEO of profi-con GmbH Con-

ing etc. and the result was a max-

tamination Control in Leipzig. He

imum of ten per cent additional

knows what he is talking about: he has seen the inside of many cleanrooms in Germany, Austria and

Break rooms often more beautiful than cleanrooms

Switzerland. His company specializes in the professional cleaning of

Colour and design, however, are

cleanrooms and they are almost al-

not useless gimmicks. Experts in

ways white.

workplace design refer to the bene-

costs, if any at all.”

All that customers want is white Why then are cleanrooms still preferably designed in white? Florian Dittel is unable to figure out

»In most companies, the break room is more beautifully designed than the cleanroom.« Duvernell, profi-con GmbH Contamination Control

why. The project manager at Dittel Engineering in Upper Bavaria Kochel am See says: “I mentioned the colour scheme in many cleanroom projects, but all the customers always wanted white. I managed to convince them of blue floors - with some difficulty.” It’s not only colours that play a role for

Frank Duvernell always hears the

ficial effect of beautifully designed

Dittel when he is designing clean-

same two reasons for this during

work environments on concentra-

rooms. Also important are space

his client meetings: “We’ve always

tion and motivation. Colours and

and lighting. “Some businesses say:

done it this way” and “We’ve nev-

shapes appeal to the senses, en-

let’s put the cleanroom in the base-

er done it differently.” Such state-

sure wellbeing and increase the

ment. That’s not possible. Employ-

ments are based on the fact that

employees’ identification with the

ees need light and space,” empha-

instead of the architects, it is the

company. Funnily enough, such

sizes the MBA graduate engineer.

engineers who decide on the design

findings are never doubted when

of the cleanrooms. For engineers,

it comes to the design of a canteen.

technical processes and function-

“In most companies, the break

2/2015

It does not have to be white: In the future, cleanroom walls could transform for example into large-area displays. The OLED technology (organic light emitting diode) makes it possible. On the walls then could be displayed paintings, landscapes, music videos or scrap rates and work instructions. Photo: Archive

The cleanroom in the basement that’s not possible

Design and functionality are not mutually exclusive

displays, switchboards and access control systems combine beautiful design with good functionality. Doors, for example, can be equipped

His advice is as follows: “Always

Thomas Christen adds that a clean-

with modern palm-vein readers that

plan from the inside out: first the

room can also be visually enhanced

look good, can be installed flush and

process, then the environment”. If

by the technical system components

are contactless. “Design does not on-

you first buy a production facili-

that are included. The co-owner and

ly create an enjoyable working en-

ty and then try to build in a clean-

technical director of vali.sys GmbH

vironment, it also offers functional

room, you will quickly face prob-

in Wetzikon, Switzerland, a provid-

benefits” says the co-owner of vali.

lems with the space and processes.

er of monitoring systems for clean-

sys. “You could even use a modern,

This could then, for example, re-

room monitoring, explains: “Most

well-designed cleanroom as a show-

sult in narrow floodgates that im-

engineers say: First, it has to work,

room and use it for advertising.”

pede the movement and flow of

and after that we can start to make

people and materials, or even un-

it look nice. However, by using the

favourable zone concepts for mate-

right design, both aspects can be

rial deliveries as well as visitor and

combined. Take stainless steel for

employee access. There is a big dif-

example – although it is more ex-

For the latter, high speed doors

ference between simply entering a

pensive than plastic, it looks better

would also be suitable. They would

house though the garage or drag-

and is easily and quickly cleaned.”

contribute lots of colour to the room

ging muddy snow from the park-

Concealed cable routing, antibacte-

if covered with an image. That leaves

ing lot into that house,” emphasiz-

rial films, or contactless operating

an impression with the visitors

es Florian Dittel. Therefore, when

systems can also visually enhance

and reduces the feeling in employ-

designing a cleanroom, a more ho-

the working environment.

ees that they are working in ster-

Designation of areas

ile rooms. Design and functionality

listic view is necessary. Of course, design should not be an

can also be merged here by design-

end in itself, underlines Thomas

ing the doors with pictures, logos,

Christen. The combination of “De-

or colours to designate certain ar-

sign top – functionality flop” should

eas. “Another possibility could also

be avoided. However, many sensors,

be to use a picture of the final prod-

2/2015

36 uct on the doors to motivate employees - and we are not referring to the

Seeing only white is like tinnitus in the ear

SCIENCE & TECHNOLOGY

fuel injectors manufactured in the cleanrooms, but the latest Ferrari,”

Alfred Schleicher reports that

says Daniel Grüttner-Mierswa. He is

many CEOs claim that their em-

Key Account Manager EMEA at As-

ployees got used to the white walls.

sa Abloy, a worldwide leading man-

“That might be true,” says the ex-

ufacturer of locking solutions and

pert, “however, what are the long-

security systems in Lippstadt.

term effects for the employees?” A

to think: What colour does the af-

colour also always creates a work-

terimage absorb, in order for the

The colour consultant and designer

ing temperature. Employees are

eye to be able to regenerate itself?

Alfred Schleicher, however, focus-

affected if they are permanent-

What working temperature will be

es on the walls, ceilings and floors. He passionately advocates to get rid of white in large cleanrooms. And for good reason: “Just as a camera cannot focus on white snow, the eye cannot focus on a white wall. This white monotony overly chal-

»If the room is only white, then it’s like tinnitus in the ear.« Alfred Schleicher, Color Consultant

lenges the eye and causes fatigue and loss of concentration in the employee,” says the owner of “Farbatel-

ly over-heated or under-heated.

transferred by the colours used?”

ier Schleicher” in Karlsruhe. He has

They are also affected if they look

says Schleicher. Thanks to research,

been developing colour collections

through a microscope with a blue

it is possible today to use light and

for building and industrial work-

background for hours and then see

colours in such a way that they

places for years.

the after-image on the white wall

achieve positive effects.

when they look up. “Here you have

2/2015

37 Stress factors in cleanrooms Stress factors in cleanrooms

Possible solutions: colours ...

• Bright permanent lighting is tiring for the eyes

• Improve physiological conditions

• Constant air pressure leads to faster fatigue

• Psychologically provide for a more en-

• Exposure to permanent cleanroom climate is problematic for the respiratory system • Cleanroom clothing and masks create an anonymous atmosphere

joyable work environment • Improve well-being and therefore create a more relaxed and productive work environment • Ensure better and longer concentration

• Shift work has a negative effect on biorhythms

• Result in less fatigue

• Lack of focal points, the so-called “white

• Reduce causes of error and reject rate

monotony” overburdens the eye • Pre-defined processes suppress independent voluntary actions and may lead to feelings of stress

Source: Alfred Schleicher, www.reinraumdesign.de

Colours provide orientation, delimitation and information

The cleanroom of the future brings the world inside

a symphony,” says the expert. He

Colours provide orientation, delim-

“Employees in a cleanroom are

recommends coordinated wall col-

itation and information. Different

closed off from the outside world

ours, gradients and contrasting

areas could, for example, be visual-

all day. Information displays could

colour edges. They would offer the

ly separated by different floor col-

show the news or music vide-

eye the necessary focusing options,

ours. Differently coloured clean-

os or the reject rates or work in-

and counteract overuse and fatigue.

room overalls also have a completely

structions,” says Duvernell about

“Rhythmic colour and lighting de-

different effect than white overalls

the future cleanroom. Even train-

sign eliminates the monotony, in-

in white spaces. Different colours of

ing sessions, wall-filling landscape

creases concentration and reduc-

overalls could represent employees

panoramas or the financing of the

es errors,” emphasizes Schleicher.

from different departments or be

cleanroom via on-screen advertis-

Splashes of colour, however, could

used to identify visitors.

ing would be technically possible.

“If the room is only white, then it’s like one single music note, like tinnitus in the ear. However, I want to listen to an orchestra playing

This is no longer a vision of the fu-

also be added to the cleanroom via monitors. These could display

“Many companies use their compa-

ture – the technologies are already

aquariums, fire, flowers, messages,

ny colour on their exterior facades,

available, says the founder of profi-

or landscapes. “Be innovative: the

at the entrance and in the stair-

con. “No matter how you use these

subject leaves room for diversity,”

wells. Why not decorate the clean-

possibilities in the cleanroom, there

encourages the colour consultant.

rooms the same way?” asks the CEO

will always be people who won’t like

of profi-con- Frank Duvernell. With

it. But there are even more people

regard to design and functionality,

who don’t like the white monotony.

he has other future-oriented ide-

And for that there are many solu-

as. Glass walls, for example, could

tions available these days.”

be turned into large-scale information walls by using OLEDs (organic

To recognize companies who are pi-

light-emitting diodes).

oneering in this area the ReinraumAkademie in Leipzig decided to

White ceiling, white floor, white overalls:The

present the most beautiful clean-

monochrome environment fatigued the

rooms with an award. The Design

Eyes, reduces the ability to concentrate and

Award is to be given for the first

increases the error rate. According to survey

time on October 28th at the Clean-

colored wall panels, diffusers, overalls and so on cost just up to ten percent more, if any. Photo: Archive

zone 2015 as a special award of the Cleanroom Awards.

2/2015

On the Effects of Colour in Cleanrooms

SCIENCE & TECHNOLOGY

A guest contribution by Alfred Schleicher, an expert in colour psychology

Very few cleanroom operators know that an all-white work environment causes psychological problems among employees. A sensible use of colour improves the work environment and reduces the risk of accidents and mistakes.

high stress and concentration and, at the same time, by soporific monotony. The predominately monochromatic and therefore monotonous general impression does

Employees in cleanrooms are al-

rhythm because monotonous and

give the employees great concen-

ready aware of the importance of

monochromatic lighting interrupts

tration, but on the other hand, this

their jobs when they enter their

the day-night cycle. In addition, the

one-sided concentration without

high-tech workplaces and put on

typically all-white work environ-

the rhythm of the passage of time

their special work clothes – a feeling

ment causes psychological problems

comes with the risk of negligence.

that is reinforced by the complexity

among employees, namely:

As a result of the increasing lack

of the expensive equipment.

of concentration, there is an in1. There are only a few focal points

However, employees in cleanrooms are exposed to several physical and mental stresses. They have to subject

for the eyes. 2. The lack of contrast puts more strain on the eyes.

creasing risk of accidents and injury from stumbling, sprains, needle sticks and cuts, chemical contact, etc.

themselves to the rhythm of pro-

3. The eyes have to keep refocusing,

duction, endure the special clean-

which quickly leads to fatigue.

These problems can be solved with

room environment, and assume a

4. The transition between tension and

a sensible and rhythmic use of col-

huge responsibility for the product

relaxation required by the auto-

our and light in the cleanroom. It

because every mistake can result in

nomic nervous system isn’t there.

counteracts the monotony, increas-

great damage to the company.

es employee concentration and re-

But that’s not all. Shift work puts

The result: Work in cleanrooms is

duces the rate of mistakes, defective

strain on humans’ biological

characterized both by prolonged

products and accidents.

About the Author Alfred Schleicher is an expert in his field. He studied colour psychology, colour design and colour systems at the International Association of Colour-Consultants in Salzburg. Today, the colour advisor and designer is the owner of “Farbatelier Schleicher” (Schleicher Colour Studio) in Karlsruhe. Schleicher develops colour concepts for public buildings and housing developments and for industrial workplaces—and here, especially for cleanrooms.

2/2015

100% quality 100% service 100% know-how 100% confidence www.profi-con.com Professional cleanroom cleaning Life Science and Microtechnology

Training around Cleanroom cleaning and behavior

About the use of light: Commonly

timum light and light colour con-

Colour not only affects our feel-

used lighting, with high and uni-

ditions in places with no natural

ings and senses but also our sub-

form light output, means that ac-

light. Light traps in doorways and

conscious. Skillful colour choice

tivities requiring differentiated

airlocks provide behaviour-regu-

therefore provides more humane

vision quickly become tiring. The

lating orientation and order.

work environments with higher

predominately white surfaces of

quality of life.

ceilings, walls, floors and equip-

We have developed special colour

ment increase the uniformity. The

collections for designing clean-

Colour choice should not be a mat-

human eye literally has no “stop-

room facilities. The use of col-

ter of the personal taste of the

ping points.”

ours provides visual rhythm in the

company owner but should be

work environment through archi-

based on the identity of the com-

A rhythm of light and colour creates

tecture, colour and light, and takes

pany. Certain messages can also be

dynamics that have a positive effect

place based on the criteria:

sent to customers externally and

on employees’ well-being and their

to employees internally through

work performance. Coloured light

• Cleanroom type

a consistent colour design in the

focal points are also possible. For ex-

• Room function

company.

ample, we could deliberately cre-

• Facility function

ate darker light zones that brighten

• Facility size

when an employee approaches (sen-

• Facility structure

sors). In addition, the light should

Text: Alfred Schleicher

(foundation, body, doors)

approximate the actual day-night

• Proportions

cycle to correspond with humans’

• Survey results from the employees

biological rhythm.

• Effect of the colours

Contrast can also be achieved in

Taking these factors into account,

the cleanroom by creating shad-

a meaningful colour combina-

ows. The lighting, which should

tion with objective criteria emerg-

always be non-glare, can be ar-

es which, in combination with the

ranged so that it creates, for all in-

floor, walls and equipment, creates

tents and purposes, shadows. The

a conciliatory, harmonious ambi-

changing play of light and shad-

ence and offers the employees a hu-

ows causes our autonomic nerv-

mane work environment. The or-

ous systems to shift gears from

dered colour relationships provide

stress hormones to endorphins.

ease and clarity in the room and re-

It is also important to provide op-

duce stress factors.

2/2015

A clean management task

SCIENCE & TECHNOLOGY

Working in and with cleanrooms must be more professional – from the planning to the cleaning. Only then is a permanently high-quality product achieved. Increasing demands on the quality of many products increase the cost of measuring and monitoring clean manufacturing environments. With modern solutions, the increased requirements can be met while keeping cost under control at the same time.

goal says, “To permanently reduce finishing time by 50% within a month by adequately planning of the establishment and personnel flow as well as a standardized clothing procedure.“

“Quality is when the customer

everyone understands the mean-

comes back, not the product,” says

ing behind it,” says the Avantalion

If measurable quality objectives

Claudia Pachl. The managing part-

partner.

are set, monitoring and tracking

ner of Avantalion Consulting Swit-

follows. This is best achieved by

zerland AG in Lucerne, Switzerland

Instead of empty phrases like “The

setting specific targets and status

stressed that quality must be gen-

customer is our focus”, the board

queries. “If you look at it regular-

erated. You cannot test the prod-

should define measurable and as-

ly, you can intervene at an early

uct in hindsight. “I have often seen

sessable quality objectives, in-

stage in cases of deviation,” says

something being continuously test-

cluding clear responsibilities and

Claudia Pachl.

ed until it was good,“ says the engi-

human, financial, and temporal re-

neer, who has many years of expe-

sources. Claudia Pachl advised that

rience as a manager and consultant

quality objectives should be formu-

in the pharmaceutical industry and

lated intelligently: specific, meas-

in medical technology.

urable, feasible, relevant, and on

Each company has its own quality policy - more or less professional. Because quality is interpreted differently by different people, Claudia Pachl recommends that all companies have a “quality policy.” This should be defined by management, fit to the corporate culture, and be understood by the staff. “Just because something is in the instructions, does not mean that From planning to production and Maintenance - operating a cleanroom requires professional management in all range. Graphics: Floor / Fotolia

2/2015

Proper Project Management saves Costs

schedule. A poorly measurable goal

But professional cleanroom man-

reads as “Get it out the door quick-

agement does not begin with the

ly to have more working time in the

setting and monitoring of quali-

cleanroom.” A concrete and smart

ty objectives. Even during the con-

41 Monitoring the cleanroom with a tablet When the cleanroom is finally build and put into operation, comprehensive cleanroom monitoring is the key to achieving the quality objectives. An innovative solution to this problem is offered by Briem Steuerungstechnik GmbH, which specializes in monitoring solutions for cleanrooms and laboratories. The company in Nürtingen in southwest GerA holistic cleanroom monitoring is the key to achieving the quality objectives.

many presented the first cleanroom

Photo: Cleanroom Media

monitoring system that is fully usa-

struction of a cleanroom, both labour and costs can be saved by

Avoiding costly mistakes

ble on a tablet. “The benefits of monitoring via tablet are many,” says Roland Ott of the

proper planning and project management. “Introducing a system in-

To avoid such mistakes, Mößlach-

Briem Steuerungstechnik. Users have

to an existing cleanroom is harder

er recommends consulting a plan-

permanent access to all the data and

than one thinks. The planning ef-

ning office before the cleanroom

the system. They get the information

fort for this is no less than building

construction, which, in close con-

exactly where they currently need it.

a new one,” says Johannes Mößlach-

sultation with the client, takes care

The tablet alerts its users if there are

er. He is a project engineer for the

of plant design and the presenta-

deviations in the production process

planning of cleanroom installation

tion of specification sheets and

and offers email and communication

at the engineering office of Dittel

project delivery. This is even more

via Facetime, so that communication

Engineering in Kochel am See in

relevant the higher the clean-

can take place face to face. Moreover,

Bavaria.

room class, and the more rooms

the tablets could document the production, and control the lights and

»Introducing a system into an existing cleanroom is harder than one thinks.« Johannes Mößlacher, Dittel Engineering

blinds. “In addition, the room layout can be displayed on the tablet to see if everything is in order in unsupervised areas or not. If not, the manager can respond immediately,” says Ott.

Suitable for all cleanroom users

Even such seemingly simple things

and locks are in the cleanroom.

The connection of tablets is via WLAN

like the subsequent attachment

“If there are changes required, the

and VPN tunnels. Ott recommends

of an outlet in the cleanroom can

cost increases significantly,“ says

careful consideration of which em-

cause significant additional costs.

Mößlacher. Therefore the require-

ployees should receive which user’s

“An electrical outlet that is calculat-

ment sheets are the most impor-

rights. “For large installations, you

ed at one Euro in the specifications

tant prerequisite for him to con-

should limit the use of tablets closely

can become thousands of Euros

trol the project schedule and to

and assign user rights depending on

when installed after construction,”

be within budget. Future build-

requirements and risk assessment.”

says Mößlacher, “because the oper-

ers, says Mößlacher from his ex-

It’s also good to consider the construc-

ator has to shut down production,

perience, will say, “Anything you

tion of the WLAN infrastructure.

turn off the cleanroom, lay the ca-

don’t plan thoroughly will catch

Here, it is a question of the range of

bles, and so on.”

up to you later.“

the devices which are to be used, or,

2/2015

SCIENCE & TECHNOLOGY

For cleanroom management also to pay attention to ease of use and low maintenance, operating and cleaning effort. Photo: Cleanroom Media

in other words, if an antenna would be needed in each cleanroom, which

Dealing with monitoring systems

management, fault management, and maintenance. There are many things to monitor in a cleanroom:

in turn could cause contamination. There are some restrictions on the

Regardless of whether the monitor-

choice of tablets, however. “The devic-

ing is carried out with tablets or at

bacterial load in retrospect, temper-

es must be fan-free and demonstra-

fixed stations, it is important for the

ature, relative humidity, differential

bly easy to clean so no important ar-

management of the cleanroom op-

pressures between the areas and air

exposure to airborne particles, total

velocities in the flow areas. Corre-

»Quality goals should be intelligent: specific, measurable, feasible, relevant, and done on schedule.« Claudia Pachl, Avantalion Consulting Switzerland AG

spondingly extensive are the requirements of the cleanroom operator for the suppliers of the monitoring systems, as regards technical features, support, operation, maintenance and servicing. Michael Müller, Managing Director of the vali.sys in Wetzikon, Switzerland, knows the problems from his daily business. “During a sales

eas are contaminated,” says Ott.

eration that it is not just about col-

pitch, there is usually no problem,

The tablet monitoring system is suit-

lecting sensor data. Monitoring al-

but then during operation, there is,”

able for all cleanroom users, from

so includes data processing, sensor

he says. Therefore, cleanroom opera-

pharmaceutical manufacturers, laboratories, cosmetic pharmacies, medical and semiconductor manufacturers to life science and biotechnology companies.

Good maintenance can be cognized because: • The consultation is intensive • The maintenance is of high quality • Staff are trained • The meters are of the highest quality and function properly • The test log is extensive and understandable

2/2015

43 tors should always be people who will

Unprofessional maintenance of-

work with the monitoring system.

ten leads to high costs, warned

Together with the future operators,

Egon Buchta. He gives an exam-

they should accurately define the de-

ple of a manufacturer whose cy-

sired functions and optimally plan

tostatic safety cabinet’s airspeed

and execute the monitoring system.

was wrong despite a filter change. There were also difficulties with

Taking operation and maintenance into account

the alarm system of the workbench. A service technician noted that the cabinet contained components that did not belong there. Instead of patented H14 filter units,

In addition to optimal usability (very

a standard H14 filter has been in-

little training needed, self-explana-

stalled that was patched, their

tory surfaces, etc.), operators should

welded profiles were torn by tight-

also do a small amount of mainte-

ening the filter, and, in contrast to

nance, care, and cleaning. Care and

the mandatory filters, would not

maintenance of the system should

keep contamination low. “It’s as if

not be an additional burden on em-

you put diesel in a petrol engine,“

ployees and should cause only min-

compares Buchta.

imal recurring costs. For everyday wear, this means using as many self-monitoring systems as possible, defining precise responsibilities in

Reducing follow-up costs

the maintenance contracts, and using easy to clean surfaces. “To enable

An expert identifies good mainte-

easy cleaning, it is advisable to plan

nance with the following points:

for coverings for the sensor probes

the consultation is intensive, the

and particle counter sampling probes

maintenance is of high quality, the

during the construction phase,” says

staff are trained, the meters are of

Michael Müller.

the highest quality and are working properly and the test log is compre-

Cheap maintenance can become costly

hensive and understandable. “All of these points are expensive,” says Buchta. “But without these costs it doesn’t work, because the effort

Egon Buchta refers to another as-

that goes into measurement and

pect of maintenance. “Be sceptical

testing is constantly increasing. But

when a service provider offers a ser-

it also helps to reduce the follow-up

vice at a surprisingly low price,” says

costs.“

the managing director of the engineering firm and cleanroom service

It is still well worth the effort. Pro-

Egon Buchta GmbH in southwestern

fessional cleanroom management

German Wannweil bei Stuttgart. This

ultimately guarantees a high prod-

could be an indication of inadequate

uct quality. And that is a decisive

qualifications, false part placement,

factor for success in the market.

or untested instruments. “Ask your-

Neither exaggerated savings nor

self if the quality of service can be

overzealous optimization can lead

guaranteed at the offered price and

to that goal. Avantalion head Clau-

request, in case of doubt, proof of the

dia Pachl puts it neatly in a nut-

qualifications of service technicians

shell, “Quality is when the custom-

beforehand.”

er comes back, not the product.”

QUALIFIZIERUNG QUALIFIZIERUNG WARTUNG WARTUNG STRÖMUNGSSTRÖMUNGSVISUALISIERUNG VISUALISIERUNG MONITORING MONITORING MESSTECHNIK MESSTECHNIK KALIBRIERUNG KALIBRIERUNG SERVICE SERVICE BERATUNG BERATUNG SCHULUNG SCHULUNG

BSR Ingenieur-Büro BSR BSR Ingenieur-Büro Meßtechnik GmbH BSR Meßtechnik GmbHim Reinraum Beratung und Service Beratung und Service im Reinraum Marienstraße 156 Marienstraße 156 68794 Oberhausen-Rheinhausen 68794 Oberhausen-Rheinhausen eMail: blattner@reinraum.info eMail: blattner@reinraum.info Tel. 07254-959 590 Tel. Fax 07254-959 07254-959 590 5929 Fax 07254-959 5929

2/2015

Clothes make the cleanroom people

SCIENCE & TECHNOLOGY

A well-designed clothing concept is essential for working in the cleanroom.

Modern cleanroom fabrics ensure compliance with particulate and microbial limits in the cleanroom. But for the products to be really reliably protected against any contamination from the outside, well-designed management is necessary in addition to highly functional fabrics. Cleanroom technology makes it possible to create controlled pro-

People: Main source of contamination

duction environments where

Filtering effect of clothing exhausts itself What does this mean in practice? The capacity of a material barrier as temporary storage or filter exhausts itself over time. This fabric barrier may thus turn into a rich source of particles if it is not decontaminat-

products are protected from par-

Thus, cleanroom clothing is of great

ticulate contaminants and en-

importance. A well-designed cloth-

vironmental conditions such as

ing concept is the basis of reliable con-

temperature, humidity and germs.

tamination control. It should always

Another task is to protect employ-

be adapted to production conditions

ees by minimizing risks that could

and tailored to the specific require-

be caused by substances and mi-

ments of the user.

ed properly and at the right time.

croorganisms. From a physiological point of view But technical solutions alone can

and for reasons of porosity, the person

not guarantee the proper func-

cannot be clothed in a “particle-im-

tioning of a clean room. Studies

pervious“ way. Thus, the material does

have shown that in spite of in-

not form a surface particle density

creasing automation, humans re-

barrier, but can only be understood

main one of the main sources of

as a storage barrier, the properties of

contamination in the cleanroom.

which can vary widely during wear.

Only good cleanroom clothing is working for a long time as a particle storing barrier. Photo: Cleanroom Media.

Consequently, decontamination is essential to complement the cloth-

Clothing management: These are the advantages of a leasing system • On-site collection of used cleanroom garments • Decontamination and sterilization according to established procedure • Identification of clothing and traceability of inventory management • Professional repair or replacement of damaged clothing • Packaging of decontaminated clothing under cleanroom conditions • Return of clothing to customers including cabinet service

ing system.

Recommended clothing elements The basis of a clothing system is to select the right fabric and the corresponding quality of workmanship. As a result, the content of residual contamination can be reduced. A variety of documents provide useful guidelines. The recommen-

2/2015

45 dations are always matched to the cleanroom process. The choice of models should always be made depending on production conditions and the demands on employees. For the different technical conditions in controlled production environments, various fabrics are available. They differ in their textile properties such as weight, type of fabric (canvass/twill weaves), pore size (air permeability), ESD properties (electrostatic discharge), abrasion resistance and various equipment (Teflon, etc.).

Paying attention to comfort Another important factor is comfort. This will depend on, among other things, technical parameters such as the so-called water vapor transmission resistance. The lower the value, the more comfortable the fabric. More meaningfully, however, are

Cleanroom clothing must protect the products reliably against contamination source Man. Photo: Cleanroom Media.

the wear test results, because every person has an individual perception

parable to common sizes for leisure-

air between the body and a clean-

of wear and comfort â&#x20AC;&#x201C; they have to

wear. As a rule, work clothes are

room overall is pumped up towards

feel good in their cleanroom cloth-

larger. Whether the clothes fit or

the collar.

ing. Another advantage of wear tests

are too big, definitely makes a differ-

is the right size allocation of items

ence, because body movements cre-

A complete clothing concept for the

of clothing that are not always com-

ate a so-called pumping effect. The

cleanroom includes intermediate

Overview of the variety of cleanroom clothing. Graphics: basan

2/2015

SCIENCE & TECHNOLOGY

With cleanroom clothing it is like with a filter: it must be carefully selected, maintained, tested and replaced if necessary. Photo: Cleanroom Media

clothing. It reduces the particle po-

out with the use of ultra-pure wa-

Cleanroom garments are is basically

tential under the cleanroom out-

ter, special liquid cleaner, drying is

like a filter. A filter must be careful-

erwear. For intermediate clothing,

done with pre-filtered air, finishing

ly selected, maintained, tested and

using a 100 percent synthetic fib-

in a specially-equipped cleanroom

replaced if necessary. The same ap-

er is recommended, as this mini-

as well as, if needed, clothing ster-

plies to clothing. If the â&#x20AC;&#x153;clothing fil-

mizes or eradicates possible fiber

ilization in an autoclave.

tersâ&#x20AC;? are optimally adapted to the in-

fragments. Intermediate clothing

dividual production environment,

prevents any contamination like-

it pays to invest in a custom-made

ly to adhere to normal underwear from entering the clean room. The

Leasing systems reduces costs

potential for contamination from

clothing concept. The advantages are obvious: maximum product and staff protection, very comfortable

street clothes is often seriously un-

In order to keep investment in

to wear, better performance among

derestimated.

cleanroom operatorsâ&#x20AC;&#x2122; apparel in

employees and efficiency in costs

check, the use of a leasing system

and processes.

Clothing must also be decontaminated

is recommended. The lessor is, in such cases, a cleanroom laundry, which takes care of the complete inventory management of clothing

In order to maintain the function-

and has the advantage of having

ality of clothing for an extended

available, at any time, the clothing

period of time, expert decontami-

needed in the right size and the re-

nation is required at regular inter-

quired number at the site in ques-

vals. This is done by a special wash-

tion. The lessor also helps prevent

ing process that differs from other

cross-contamination in the prepa-

purification methods, because the

ration process and during return

clothes are not so much cleaned by

delivery to the customer, and cloth-

mechanical friction as by special

ing items can be exchanged if they

rinses. Decontamination is carried

lose their functionality.

2/2015

Pumping Effect:Through movement, contaminated air often escapes through openings in cleanroom clothing, especially in the head and neck region. For this reason, intermediate clothing suitable for cleanrooms is essential. Photo: dastex

Das bisschen Haushalt …

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Weitere Informationen unter Telefon 0541/7101128

www.tdh.de/hausangestellte 2/2015

What do you do, Damaris Steyernagel?

SCIENCE & TECHNOLOGY

A short profile from the cleanroom industry

“My name is Damaris Steyernagel.

baby. These special nutrition solu-

in which the air is purified again

I have been a pharmaceutical tech-

tions are fed to the premature in-

through special filters. The amount

nical assistant at Klinikum St. Georg

fants and sick newborns via an in-

of air pollutants and the tempera-

in Leipzig for 15 years. I make paren-

fusion into the bloodstream. In this

ture and pressure in the rooms are

teral food for premature and new-

way, the still underdeveloped gas-

monitored constantly, 24 hours a

born babies in the GMP division of

trointestinal tract can slowly get

day, 365 days a year.

our hospital pharmacy. This means

used to the complicated process of

making sterile nutrient prepara-

digestion.

tions for infusion. That means that

This is how Klinikum St. Georg’s new GMP and drug manufacturing

I have to guarantee the sterility of

Infusions for premature infants

division achieves the highest lev-

the nutrients. That’s why I work in

cannot contain any germs. There-

el of hygiene and makes a signifi-

a cleanroom.

fore the highest hygienic standards

cant contribution to pharmaceu-

are observed in the GMP division

tical therapy and patient safety.”

The food for premature infants

of Klinikum St. Georg. The air is fed

must contain important nutrients,

into the rooms through sterile fil-

calories, electrolytes, vitamins and

ters and is scrubbed continuously.

micronutrients. I make it myself,

The parenteral nutrition solutions

precisely to match the needs of each

are made in a laminar flow cabinet

2/2015

Damaris Steyernagel is a pharmaceutical technical assistant (PTA) in the hospital pharmacy at Klinikum St. Georg in Leipzig, a specialized care hospital in Saxony. Photo: Klinikum St. Georg

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www.cl-ex.com Das Wissensportal der Reinraum-Branche. 2/2015

The new Annex 15 what should you do?

SERVICE

The most important changes at a glance

The revision of Annex 15 “Qualification and Validation” of the EU GMP Guide will take effect on October 1, 2015. The new version is considered to be binding within the European Union and is in alignment with international regulations such as the U.S. FDA.* This revision became necessary to

Qualification

better reflect the current state of

based on “new” or “complex” technologies. Since the annex does not mention any specific criteria for these technologies, the companies can perform IQ and OQ tests simultaneously with the FAT at their own discretion (IQ = installation qualification, OQ = operational quali-

science, technology and practice,

The new Annex specifies user re-

fication). However, it must be en-

which was not covered adequately

quirement specification (URS).

sured that the qualifying processes

in the previously applicable version

Basic quality elements are clear-

cannot be retroactively affected by

from 2001. Companies that already

ly defined at the beginning of the

transport or construction.

operate GMP-compliant systems

qualification. The fixed URS serves

meet the requirements of the new

as a reference point and is valid

Annex 15. However, the changes

through the whole lifecycle. This

and additions ensure long-term

way any risks of the GMP can be

Retrospective validation is in prin-

guarantee of the processes. Com-

identified and minimized as early

ciple no longer allowed under the

panies will need to provide proof

as possible in the process, as well

new Annex 15, so that processes

of this in the future.

as throughout the whole process.

which so far have not been validat-

Since the practical design and im-

ed must be re-validated. The contin-

Amounting to 16 pages, the revised

plementation of the URS is ex-

uous process verification (CPV) is a

Annex 15 is significantly larger than

tremely dependent on the needs

completely new approach. Although

its previous version. In particular,

and production conditions of each

the annex does not specify the im-

the rules for cleaning validation

company, Annex 15 only regulates

plementation of this approach, it

were clarified and expanded. How-

the general conditions.

is clear that the continuous obser-

Validation

vation of the manufacturing pro-

ever, the core of the document is the concept of the lifecycle. This

Another new element that is close-

cess requires systematic planning

model is used with devices, prod-

ly related to the URS, is the design

during the development of products

ucts and processes, as well as for

qualification (DQ), which has the

and processes. Despite the new ap-

qualification and validation with

function of ensuring alignment

proach, the continuation of the tra-

direct consequences for quality risk

with legal requirements and the

ditional 3-batch validation is still

management (QRM). The “General”

provisions of the URS. However,

possible and requires only a few

section of the Annex clearly states

Annex 15 does not specify time in-

modifications to comply with the re-

that QRM should consistently re-

tegration of design qualification

vised rules. The so-called hybrid ap-

late to the entire product lifecycle.

in the entire qualification process.

proach combines elements of both validation methods for the different

The risk analysis can therefore react to changes in the life cycle in

Another change is a mandatory

future.

factory acceptance test (FAT) pri-

2/2015

manufacturing steps.

or to the acquisition of new equip-

A bracketing approach can reduce

ment, particularly those that are

the validation effort in certain cas-

51 es. This may be the case for only

Visual inspection has now official-

gards to manual processes, variable

minimal changes to the product

ly been introduced for the first time

factors such as employees must be

or in shifting the place of manu-

as an important acceptance criteri-

taken into account. Worst case con-

facture, but an in-depth process

on. Additionally, the Annex also in-

ditions must always be applied in

knowledge and compliance with

troduces a toxicological evaluation,

validation.

the existing product approvals are

which is a method to determine the

required. The previous possibility

acceptance limits of residues result-

of concurrent validation is hence-

ing from the primary product.

Text: Thomas Köhler

forth only permitted in exceptional cases.

In campaign production, companies

* US FDA: The Food and Drug Ad-

must now accurately define not only

ministration (FDA) is the central au-

The new rules clarify and explain

the production period and the batch

thority in the U.S. for food monitor-

many points in further detail with

number for cleaning validation, but

ing and drug approvals. It controls

regard to the cleaning validation.

also the option of cleaning between

not only products produced in the

This creates not only greater le-

batches.

U.S., but also imported products.

The revised version of Annex 15 „Qualification and validation“ of the EU GMP Guide supports the alignment with international regulations such as the rules of US Food and Drug Administration. Graphics: Weissblick

gal certainty, but also adapts the

Differentiating and taking into ac-

regulations to the already estab-

count different levels of automation

lished procedures in practice. In

also play an important role in clean-

particular, the annex now includes

ing. This needs to be taken into ac-

the following aspects: toxicological

count now as well, as part of the val-

evaluation, the use of quality risk

idation. With automated processes,

assessments to define the cleaning

cleaning validation must now in-

validation and automated cleaning

clude the total specific bandwidth

processes.

of the production resources. In re-

2/2015

SERVICE

The Cleanroon Award 2014 won the Initial Textil Service GmbH for its new Clean Vision cleanroom suit. Photo: Sandra G채tke / Messe Frankfurt Exhibition GmbH

2/2015

A prize for the most beautiful cleanroom

For the very first time, a special prize, The Design Award is to be presented in the Cleanroom Awards at Cleanzone 2015.

Innovative ideas from the leaders of the cleanroom industry can be submitted for the Cleanroom Award 2015 until 31st August. Furthermore, the Cleanroom Academy will, for the very first time, award a prize for the most beautiful cleanroom. Attractively designed production environments that have more to offer than white walls are now being sought.

and it will be the exhibition visitors

Cleanroom Award. In addition to

themselves who will decide the win-

media attention for their company

ner of the Cleanroom Award. Us-

and its innovation, a cash prize of

ing ballots, they will vote for their

3,000 Euros, donated by the Clean-

choice of Cleanroom Innovation of

room Academy, serves to tempt po-

the Year and thus the winner of the

tential contestants.

Cleanroom Award and Design Award: How to apply What can be submitted? For the Cleanroom Award 2015, the Cleanroom Academy is looking for the best ideas on the topics of cleanroom innovation, sustainability and energy efficiency. These must go beyond marginal changes to existing

The application period for the Clean-

products and services. It does not matter whether the concepts have

room Award is coming to an end. Au-

already been implemented or only exist as a sketch.

gust 31st 2015 is the deadline. We are looking for ideas that give companies

Furthermore, for the first time, the Cleanroom Academy will be ho-

in the cleanroom industry a compet-

nouring the most beautiful cleanroom. We are looking for applications

itive advantage or increase efficien-

from companies whose clean rooms have more to offer than just whi-

cy. Applications will be accepted from

te walls, i.e. designs and colour schemes that contribute to the welfa-

individuals, companies and research

re and identity enhancement of staff.

institutions. The Cleanroom Academy in Leipzig is once again looking

When is the deadline?

for smart ideas on the topics of in-

The deadline for applications for both the Cleanroom Award as well

novation, sustainability and energy

as the Design Award is August 31st 2015. Participation is open to com-

efficiency.

panies, institutions, academic institutions and individuals.

A jury will select five top candidates

Where should documents to be sent?

from all the applications submit-

Applications for the Cleanroom Award and the Design Award should

ted before August 31st. At CleanZone

be sent to the following address:

2015, the finalists can then publicly present their innovations. “Clean-

Cleanroom Akademie GmbH

zone - International Trade Fair and

Keyword „Clean Room Award“ or keyword „Design Award“

Congress for Cleanroom Technolo-

Rosa-Luxembourg-Str. 12-14

gy” takes place on 27th and 28th Oc-

04103 Leipzig

tober 2015 and will be held at the

Tel .: +49 341 98989 302

trade fair in Frankfurt, Hall 4.0.

Email: info@reinraum-akademie.de

The five award finalists will make

Internet: www.reinraum-akademie.de

their presentations on the first day

2/2015

SERVICE

Frankfurt, offers next to the enterprise presentations a two-day conference program with top-class expert presentations (above) as well as panel discussions in the Clean Zone Plaza, this year, among others, with the themes youth, education and recruiting. Photo: Sandra Gätke, Messe Frankfurt Exhibition GmbH.

Design Award celebrates its premiere

of the Cleanroom Academy, Frank

increase motivation and the abili-

Duvernell, wants to use this prize

ty to concentrate, resulting in less

to steer the attitudes of cleanroom

waste and fewer sick days,” says

In addition, visitors will get to

operators towards the positive ef-

Frank Duvernell.

see a debut. For the first time, the

fects of beautifully designed clean-

Cleanroom Academy is also pre-

rooms. “Experts have proven that

Applications for the new Design

senting a Design Award for the

colour and design contribute a lot

Award, as well as submissions for the

most beautiful cleanroom. It is a

to the well-being of employees.

Cleanroom Award, can be sent to the

special prize for this year’s Clean-

Unlike stark white work environ-

Cleanroom Academy until 31st Au-

room Awards. Managing director

ments, well-designed cleanrooms

gust 2015 (see box).

2/2015

“The Effects of Light and Color” Swiss artist Beat Toniolo helps the Cleanroom Award Jury in selecting candidates for the most beautiful cleanroom.

Cleanroom Magazine: For the first

zones. Customary mainly means

time, a Design Award for the most

“safe.” But I can only experience new

beautiful cleanroom will be present-

perspectives if I leave my comfort

ed at Cleanzone 2015. What are the

zone. In other words, I can only dis-

criteria for the applicants?

cover new paths if I take detours.

Beat Toniolo: We’re looking for com-

Cleanroom Magazine: What fac-

panies that live by a company philos-

tors will you pay special attention to

ophy. This should be reflected not on-

when you’re evaluating the applica-

ly in the exterior design but also in

tions for the Design Award?

the reception area, the stairwells and, in our case, of course, in the clean-

Beat Toniolo: For me, the company

room. That means we’re looking for

philosophy is important, as well as

About the interviewee: Beat Toniolo

concepts that go beyond the pictures

the background to the transforma-

is a Swiss artist who has lived in Leip-

in the hallway.

tion; that is, what are the reasons

zig since 2010. After studying to be a

for the current type of design? Were

pharmacist, he left that profession to

Cleanroom Magazine: The winner of

the employees involved or did the

train as a physical therapist in Munich

the Cleanroom Award will be chosen

boss dictate everything? Maybe art-

and Stuttgart, coached participants in

by the public visiting the trade fair.

ists were even asked to design some-

European and world championships

Will that also be the case with the De-

thing along with the employees. An-

and he then developed programs for

sign Award?

other interesting aspect would be: is

health education in the workplace. Af-

the design permanent or can it be al-

ter 1990, he became involved in the art

tered from time to time?

world and took art and cultural tours

Beat Toniolo: It would be a good idea to do this along the lines of the Clean-

throughout Europe. Since 1996, he has

room Award. We haven’t finished

Cleanroom Magazine: In your opin-

done exhibits, installations, festivals

making our decision on this yet.

ion, why are colour and design im-

and short films, and uses provocative

portant in a cleanroom?

political performances to draw atten-

Cleanroom Magazine: Most clean-

tion to critical social issues.

rooms are white because it conveys a

Beat Toniolo: Because people accept

feeling of purity. Doesn’t colour ruin

something more easily if they like

this impression?

it. In many cleanrooms, the light is too cold or too bright because of the

Beat Toniolo: Standards have to be

white walls. On the other hand, col-

followed in cleanrooms, so many

ours and pleasant lighting affect hu-

cleanrooms are simply white. An-

mans very differently; they create

other reason is, people have become

alternating stimuli. Ergonomic de-

accustomed to it. Cleanrooms are

sign must be part of that. It’s no good

white, and it’s always been that way.

if everything is nicely designed, but

Changing this means the people in

people get hurt because of incorrect

charge have to leave their comfort

posture or processes.

2/2015

License for knowledge

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At the portal www.CL-EX.com, a unique collection of cleanroom knowledge is available.

With a membership, users receive one year’s access to technical articles, videos, photos, graphics, and checklists that can be used without restriction for solving professional tasks or to prepare for presentations. Of what use are dry seals in cross bandraster ceilings? What requirements

More than 70 Gigabytes of Knowledge

do today’s monitoring systems need

users is obvious: whereas before, users needed to gather together fragmentary cleanroom knowledge from the websites of various manufacturers and service providers, now it is available at www.CL-EX.com, all together in one place, prepared and well-structured. With more than 500

to fulfill? What’s new in cleanroom

Meanwhile, more than 70 gigabytes

feature stories, the portal provides

clothing? The Cleanroom Experience

of collected cleanroom knowledge

a unique collection of cleanroom

Knowledge Portal offers answers to

is available to everyone through the

knowledge. It includes profession-

these and many other questions at

Knowledge Portal. This unique on-

al articles and presentations, video

www.CL-EX.com. Here, the Leipzig

line reference offers numerous op-

interviews with experts from sever-

Cleanroom Academy collects practi-

portunities to expand one’s knowl-

al countries, film clips, training ma-

cal knowledge on all aspects of safe

edge on the subject of cleanrooms,

terials, charts, checklists, and a pho-

cleanroom operation.

quickly and easily. The advantage for

to database.

E-Learning: Anyone who wants to learn about cleanrooms, no longer has to click on countless websites of various providers. In the Internet Portal www.cl-ex.com are 70 gigabytes bundled cleanroom knowledge in one place on the Internet. Photo: soli Images / Fotolia

2/2015

E-learning: In the Internet portal www.cl-ex.com are available 70 gigabytes bundled cleanroom knowledge. Photo: soli Images / Fotolia

The license for knowledge

on the bottom, and always can be

the large search box at the top of

clicked on from the top of the page

the homepage at www.CL-EX.com.

header.

The field reads, “What cleanroom

Using the portal is both simple and

topics interest you?“ Here, users

inexpensive. A yearly membership

The contents in “Knowledge“ include

can enter any search terms they

costs only 98€. Immediately after

expert interviews, visuals, photos,

like. Someone who wants a target-

registration at www.CL-EX.com, in-

training videos, articles and more.

ed search can click on the button

terested users are given access. Dur-

Many of the contents can be down-

to the right of the search field labe-

ing the membership, users can ac-

loaded as PDF files and transferred

led “Detailed Search.“ This will open

cess all content freely and use it

to one’s own private documents or

a menu where specific media, sec-

without restriction for work, for

presentations. It is also possible to

tors and topics can be pre-selected

presentations, training, or lectures.

gather relevant findings into collec-

by clicking.

Registration on the Knowledge Por-

tions to read them later.

tal has no risks connected to it, the

The Cleanroom Experience mem-

Cleanroom Experience membership

Under the button “Experts Days,“ all

bership expires automatically after

expires after one year.

events like Experts Days, New Year’s

one year if an extension for anoth-

and autumn receptions organized by

er year has not already been made.

Membership is not only for individ-

the Cleanroom Academy in Germa-

There is also a YouTube video that

uals, but also companies. The ad-

ny and in Switzerland are published.

can be viewed on smartphones and

vantage of corporate membership

Knowledge Portal users will not only

tablets with the adjacent QR Code

is that several people can work with

find conference content, dates, and

and offers information on the struc-

the Cleanroom Experience Knowl-

venues, but also the opportunity to

ture and content of the Knowledge

edge Portal simultaneously. A total

book their participation online via a

Portal.

of three types of corporate mem-

registration form.

berships are available: for five, ten, and 20 employees. Memberships cost

The third area, “Competence Cen-

440€, 780€, and 1,450€ respectively,

tre,“ provides information on the

each for an entire year.

two Cleanroom Experience Compe-

Simple Navigation

tence Centres in Germany and in Switzerland. In both places, there are exhibition and event spaces, train-

In order to make it easy to find

ing centers and get-together areas

your way through the large body of

for meetings, seminars and custom-

knowledge, the Cleanroom Experi-

er presentations.

ence Knowledge Portal www.CL-EX. com is structured simply and clearly, in three areas of “Knowledge,“ “Ex-

Finding instead of searching

perts Days,“ and “Competence Centre.“ These three areas are found

But the fastest way to find the clean-

both on the homepage, as well as

room information you need is in

2/2015

Trade Fairs and Congresses

18.-20.08.2015 China (Guangzhou) International Cleanroom Technology & Equipment Guangzhou (China)

Kiel

06.-08.10.2015 BIOTECHNICA and LABVOLUTION 2015 Hannover (Germany)

Schwerin

Hamburg

Germany

Bremen

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Hannover

Berlin Potsdam Magdeburg

30.09.-03.10.2015 exopharm Dusseldorf (Germany)

Leipzig Düsseldorf

16.-19.11.2015 MEDICA und COMPAMED 2015 Dusseldorf (DE)

Erfurt

Dresden

Köln

Frankfurt am Main

Wiesbaden

Nürnberg

Mainz

10.-14.10.2015 Anuga Cologne (Germany)

Saarbrücken

27.-28.10.2015 cleanzone Frankfurt am Main (Germany)

Stuttgart

München

18.–19.11.2015 Precision Fair Veldhoven (Netherlands)

München

Konstanz

Basel Aarau Delèmont Solothurn

Zürich

St. Gallen

Wangen

Neuenburg

Luzern

15.-16.09.2015 Swiss Medtech Expo Lucerne (Switzerland)

Freiburg

Chur

Lausanne

Genf

Switzerland

2/2015

Bern

06.-08.10.2015 SEMICON Europa Dresden (Germany)

10.-13.11.2015 productronica Munich (Germany)

Events ReinraumAkademie (Germany) CleanroomAcademy (Szwitzerland) CLEANROOM EXPERTS DAYS 23.-24.09.2015 | Fitness and Ergonomics in Cleanrooms | Leipzig (Germany) 30.09.-01.10.2015 | Professional Cleanroom Management | Wangen an der Aare (Switzerland) 18.-19.11.2015 | Cleanroom Design | Wangen an der Aare (Switzerland) 24.-25.11.2015 | Cleanroom Behaviour, Cleaning and Training | Leipzig (Germany)

TAGESTRAINING PLUS 06.10.2015 | Wangen an der Aare (Switzerland) 08.10.2015 | Aschaffenburg (Germany) 10.11.2015 | Leipzig (Germany)

PROFESSIONAL SEMINARS 28.-29.09.2015 | Fundamentals of Professional Cleanroom Cleaning | Wangen an der Aare (Switzerland) 11.-12.11.2015 | Fundamentals of Professional Cleanroom Cleaning | Leipzig (Germany)

2/2015

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Chefredakteur Frank Baecke Tel. +49 341 98989 405 frank.baecke@cleanroom-media.com Translation www.offstimme.com Writers Frank Baecke Alfred Schleicher Piet Felber Thomas Köhler Frank Duvernell Maja Franke Advertising Maja Franke Tel. +49 341 98989 404 maja.franke@cleanroom-media.com

Internet www.cleanroom-media.com

Cleanroom Award – Advancement for the Cleanroom

Well dressed in a Cleanroom

spring 2015

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Gut gekleidet im Reinraum Fortschritt für den Reinraum

Regularien Lästige Pflicht oder geldwerte Tipps? OLEDs Die Lichtrevolution aus dem Reinraum Krankenhauskeime Wie Raumtechnologien Infektionen verhindern

MAGAZINE

Cleanroom Award – Challenging the branch

Cleanroom Award –

Life & Science Information for Cleanroom Technology

Herausforderung an die Branche

So nehmen Pollen und Luftfeuchtigkeit Einfluss auf Ihre Produktion

CLEANROOM

Cleanroom Award –

Implementation Wohlfahrt GmbH www.wohlfahrt.net Publication Quarterly Circulation 10.000 copies Printer Löhnert-Druck, Leipzig ISSN 2364-0405

ISSN 2364-0405

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Editor’s note We thank all photographers for editorial support. Unfortunately, not all image-authors are especially determined. Any claims remain, of course. Please login from the publisher.

Frühjahr 2015

Life & Science Informationen für die Reinraumtechnologie

The influence of pollen and air humidity on your production

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Ausgabe 1/2012