VISIONARY BREAST CENTERS BUSINESS PLAN
“Personalized Breast Care for Life” June 22, 2014 For more information contact: Dr. Phillip Bretz Chief Medical Officer TamDoc@aol.com (760) 898-0164
Visionary Breast Centers Business Plan 06.22.14
The Company
EXECUTIVE SUMMARY
Visionary Breast Centers (“Visionary BC” or “VBC” or the “Company”) was specifically formed to address the acute need for more effective, safer, and lower cost breast cancer screening tools and treatments. The goal of Visionary BC is to use cutting edge technology without radiation to identify ultra-small breast cancers which enables us to use cryogenic probes and liquid nitrogen to kill the cancer without surgery, chemotherapy or radiation. The Lavender Procedure—so named because nearly every patient, immediately following their procedure walks across the street from our office to the Lavender Restaurant and has dinner and wine—without even a stitch or butterfly suture needed. The Company’s mission is to dramatically increase life expectancy and to eliminate the need for debilitating and costly chemotherapy, disfiguring surgery and radiation treatments for women diagnosed with breast cancer. Visionary BC expects to accomplish this goal by incorporating six cutting-edge technologies providing more effective tools to identify breast cancer at its earliest stages before it has the chance to metastasize, and many years before it is detected by traditional methods, allowing the use of less invasive treatments eliminating traditional treatments with toxic chemotherapy and damaging radiation. A growing number of Visionary Breast Centers will be established as free-standing clinics which will own and utilize the key components of these cutting-edge technology practice protocols, including the Lavender Procedure. Visionary BC will acquire the assets of four technology companies in various stages of distress, to own the key portions of this revolutionary practice protocol our which individual Visionary Breast Centers will be built upon. These targeted acquisitions include a genetic-based breast cancer predisposition test, digital infrared imaging, an at-home-based pressure-sensor breast screening device and a ductal carcinoma cell screening device. Visionary BC is currently in the process of acquiring the assets for the Infrared Breast Imaging (IBI) system which employs state-of-the-art digital infrared imaging to detect breast cancer at a lower cost, more safely, non-invasively, and earlier than conventional screening methods. The IBI system is completely free of known dangers associated with X-ray radiation and physical discomfort of traditional mammographic procedures. The IBI system works by detecting minute changes in the body’s heat signature. It analyzes these minute changes using a sophisticated statistical algorithm pinpointing abnormal physiologic activity, such as angiogenesis (blood supply to a new tumor), which often signals a cancer or malignant lesion. The IBI system received FDA marketing clearance in 2004 and European Union CE Mark (marketing approval) in 2006. Currently, this system is adjunctive (auxiliary to other existing procedures) which physicians can use to screen for and isolate pre-cancerous and cancerous tumors. The IBI system has been shown by itself to detect breast cancer several years before conventional methods currently used. Breast cancer is a deadly disease. This year more than 200,000 American women will be told they have breast cancer and another 40,000 women will die. Approximately one-third of breast cancer deaths occur in women under 50. Death from breast cancer can virtually be eliminated if it is routinely diagnosed at an early stage. When detected early, patients have significantly greater long-term survival rates than those whose cancer is detected at later stages. The five-year survival rate for breast cancer is 98% if detected while still localized to the breast. The survival rate drops to 83% or less if cancer reaches the lymph nodes, it then drops to 26% if cancer invades other organs. However, most breast cancer is not diagnosed early enough. With the known shortcomings of mammography, the Company expects to greatly improve early breast cancer detection rates. This is $3.75 billion dollar market for the Infrared Breast Imaging System alone at $75 per test. In the U.S. there are over 50 million mammograms performed each year.
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The Devastation of Cancer
BUSINESS PLAN
The effects of cancer impact us all, whether personally or through family and friends. Over 559,000 Americans die each year from some form of cancer, and each day over 1,500 lives are cut short by this disease. The financial impact is just as grim. The National Institutes of Health estimates that the costs of all cancers cost Americans over $209 billion each year, with $74 billion in direct medical costs, $17 billion in lost productivity due to illness, and $118 billion in lost productivity due to premature death. A significant portion of this excess morbidity and mortality of cancer is due to the late detection of the disease. If detected early, most cancer patients have greater long-term survival rates than those detected at later stages of this dreaded disease. Over 2.2 million women in the U.S. have been diagnosed with breast cancer, and each year an additional 200,000 women are diagnosed and another 40,000 women die each year of the disease. Of the 40,000 women who die each year in the U.S. from breast cancer, one-third of these deaths occur in women under the age of 50. The American Cancer Society data show that 98% of the women are alive after five-years if the breast cancer is identified and treated while the cancer is still localized to the breast. The survival rate drops to 83% or less if the cancer travels to the lymph nodes, and if cancer invades other organs the five-year survival rate is only 26%. These statistics clearly indicate that the earlier breast cancer is diagnosed, the greater the probability of long-term patient survival. Ineffective Diagnostic and Treatment Protocols The problem women face globally is inadequate or nonexistent diagnostic and treatment modalities for breast cancer. In the U.S. the same number continue to die (40,000) decade after decade despite all the efforts at research. By 2030, 70% of all breast cancers will occur outside traditional countries and will occur in China, India, Brazil etc., countries ill equipped to handle this impending burden. Even today for example 50% of women in India never receive any treatment for their breast cancer and eventually die. Long ago we asked the question, “what if all this tragedy was unnecessary?” We think it is, and have worked out the solution using FDA-cleared technology that has been summarily dismissed by the western medical system. The answer is in the melding of those technologies. To accomplish this mission Dr. Bretz has founded Visionary Breast Centers (VBC). VBC will be the diagnostic and treatment arm of the enterprise in the U.S. and worldwide. VBC will acquire and/or license technology from various companies where Dr. Bretz has researched their diagnostic and treatment modalities for many years. Breast cancer which has plagued women for decades and the mortality numbers are constant annually, with approximately 40,000 women continue to die each year from this disease. In 1971, President Nixon signed the National Cancer Act and as a result institutions such as SloanKettering, MD Anderson, Dana-Farber and Fred Hutchinson Cancer Centers were born. At that time, we decided as a country to diagnose and treat cancer with ever more complicated surgeries, aggressive chemotherapy and extended radiation. In short, the mentality was, the more treatment, the better. Forty years later, this approach has proved not to be true in all cases. An April 2014 Oncology Times article quote (says what? Put quote here). In short, these huge cancer centers are sustained on enormous amounts of money coming from multitudes of treatment and contributors who believe in the status quo. Visionary BC’s technology and approach is ‘Disruptive’ in that we use unconventional modalities but also the U.S. cost savings alone could exceed $10 billion annually.
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The solution is a technology that can identify breast cancer at its earliest stages to make life-saving early diagnosis possible. Though breast cancer has been a deadly disease it can be treated very successfully without chemotherapy and radiation provided the cancer is detected early. Survival depends on finding the cancerous growth at its very earliest stages and before it has spread. The Solution The solution is the utilization of novel genetic predisposition testing, non-ionizing monitoring methods and cryogenic treatment technologies to optimize the impact in diagnosing and treating breast cancer at its very earliest stages. Dr. Bretz had researched and successfully utilized these technologies for the last six years. His institute is the only location where these technologies are utilized side-by-side. The Visionary Breast Center Treatment Protocol includes: OncoVue™ Genetic Testing A saliva-based breast cancer risk test (not BRAC 1&2 made famous by Angelina Jole). It not only tells a woman’s risk for breast cancer but most importantly when that risk is likely to manifest within a 10 year period during her life. Dr. Bretz actually was a principal investigator in their FDA clearance clinical trial. Modified Military Digital Infrared This technology is much different than the old IR back in the seventies. It incorporates a neural network (artificial intelligence) to help diagnose breast cancers, it learns from itself. It eliminates harmful radiation as use in X-ray mammography, it simply measures the heat signature differentials coming from the breast indicating higher metabolic activity and heat signature differences. At the earliest stages of breast cancer development, small numbers of cancer cells rapidly multiply and give off heat signatures that can be detected as nascent tumors, three years before they can be spotted by traditional X-ray mammography. Dr. Bretz has a white paper describing the first 500 patients monitored with this technology and shows a sensitivity of 97% and specificity of 79% with a false negative rate of 0.4%. The false negative rate for X-ray mammography after fifty years of refinement is 20%. The infrared exam takes 4 minutes to complete and results are available immediately. Unlike digital mammography which is costly and immobile, IR is portable. This aspect is indispensable for utilization in developing countries.
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Pressure sensing technology This device is currently in laptop form and has pressure sensors that are rubbed over the breast and can detect tumor masses at about 5mm. The real story is that that Suzanne Sommers is very interested in helping to market this hand held-device for home use once we reach this stage. This device can give the doctor an indication of the growing tumor being benign or malignant. Halo This testing device attaches to the breasts and first gives a warm water bath for approximately three minutes then provides a suction action that can find individual cancer cells that may be attached inside the breast ducts where 90% of breast cancers form. This technology can identify breast cell abnormalities years before they are detectable by other means. It’s like having a biopsy, without the biopsy. Ultrasound
Dr. Bretz uses state-of-the art technology from Hitachi with Elastography. Elastography shows in color the high likelihood of a tissue mass being solid, malignant or otherwise. This technology routinely captures images of masses 1mm in size.
Current Methods of Breast Cancer Screening and Detection The most common and widely used screening method is X-ray mammography. More than 50 million mammographic procedures are conducted in the US every year and this number is growing by 10% per year. Mammography is an X-ray image of the breast and examines the anatomy of the breast at the moment of the examination but it cannot tell the doctor and the patient anything about the physiological state of the breast. If the cancer or tumor has not yet reached a sufficient size to be distinguished from the surrounding dense tissues, the mammogram provides little useful information to the doctor and the patient. Other diagnostic methods for breast cancer screening include Clinical Breast Exams (CBE), ultrasound and MRI. Clinical Breast Exams require that a lump can be felt by palpation. By the time a lump in the breast can be felt, it means that the tumor has grown to a significant size. Most often theses cancers have been growing for as many as 10 years in order to reach a size that it can be felt through a CBE. This is not an effective method of early breast cancer detection. Ultrasound is another tool used currently, however it requires great skill and significant expenditure of time. MRI is a highly sensitive tool for the detection of breast cancer, but. More often the not radiologists will want to repeat the exam because it does pick up more targets then mammography. MRI is exorbitantly expensive, costing between $1,000 and $2,500 per exam, which does not make MRI an option for general screening of all women globally for breast cancer. The shortcomings of these current methods provide a significant opportunity for a technology that is highly sensitive, safe, easy to use, mobile and economical for screening all women for breast cancer. Furthermore, the liability of the physician will be reduced with fewer “failure to diagnose� claims for breast cancer.
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Problems with Mammography as a General Screening Tool for Breast Cancer The current gold standard for breast cancer screening is mammography. However, there is considerable dissatisfaction with mammography for many reasons. 1. Mammography is relatively insensitive in women with dense breast tissue, which is frequently the norm in younger women and is not uncommon after menopause. Thus, many tumors are missed by mammography. Daniel Kopans, professor of Radiology at Harvard University, notes that 70% of the cancers that are diagnosed by mammography can be seen in retrospect to have been present the previous year. In other words, they were missed at the time of the earlier mammography study. The percentage of these cases is actually likely to be much higher than 70% as radiologists are reluctant to point out how many cases of missed cancers they have encountered. 2. Mammograms are difficult to read and interpret, and require an experienced radiologist with significant history in reading mammograms. Radiologists who read mammograms (mammographers) are required to spend thousands of hours reading mammograms in order to be qualified to read patient’s mammograms. In addition, there are fewer and fewer radiologists willing to enter this field of medicine due to the challenges, the tedious work and the liability. 3. There is a finite danger in the routine annual exposure to X-ray through mammography. It is estimated that 20 mammograms during a person’s lifetime is equivalent to standing approximately 1 mile from Hiroshima when the atomic bomb exploded. Although, mammography has been vital to saving lives due to breast cancer, it is not without its inherent risks. A former director of the NIH believes the risk for breast cancer goes up 1% with each mammographic study. X-rays are cumulative they don’t go away. 4. Women have difficulty with the procedure itself due to the pain and discomfort associated with the procedure. Because the breast must be squeezed between plates prior to an X-ray being taken, it can only image the portion that is between the plates and many breast cancers are undetected because they are not within the field of view. 5. For physicians and institutions to offer mammograms, the cost of acquisition of all the mammographic equipment and support systems is approximately $500,000 to $1,000,000. It then requires the staffing of full-time radiologists specializing in reading mammograms. The cost of employing a radiologist can run approximately $250,000 annually. Since the implementation of the National Cancer Act in 1971 the mortality from breast cancer has dropped a scant 5% overall while subsets of women, such as African-American continue to have much worse outcomes than others at much earlier ages. Why then after nearly forty years are the same percentages of Americans dying from cancer as in 1950? The statistics are that more Americans will die from all forms of cancer in the U.S. in the next sixteen months than have perished in every war the nation has ever fought combined. Much of the problem is due to the lack of effective methods to detect cancer early enough. Early detection of cancer saves lives for all forms of cancer. The five-year survival rates for lung cancer increases from approximately 20% to 85% when detected and diagnosed at an early stage. However, only 15% of lung cancers are found at the localized early stage. The current five-year survival for colon cancer is 61%. When colon cancer is detected very early the five-year survival rate climbs to 91%, however, less than 40% of colorectal cancers are discovered at this stage. 6
Visionary Breast Centers Business Plan 06.22.14
With the new Federal Task Force guidelines, changes have been made such that recommendations for screening of women for breast cancer has now moved from beginning at 40 years of age and every year thereafter, to now 50 years of age and every other year thereafter. These changes are being implemented immediately by the State of California and most likely will result in many more women going undiagnosed with breast cancer, or identified at much later stages. Significantly, a younger Medi-Cal group is not offered routine X-ray mammography and insurance companies do not cover patient initiated mammography requests. In addition, the normally dense breast tissue of younger women frequently limits the diagnostic value of X-ray mammography. Digital Infrared Technology Background Digital infrared technology was developed for the U.S. Government and was declassified in 1992 shortly after the first Gulf War. The military, law enforcement and border patrol all use infrared cameras to sense heat that is associated with human beings. From infrared cameras on sniper rifles to cameras aboard the Predator and Raptor to cameras on the THEL (Tactical High Energy Laser) weapons systems, they all utilize infrared and it has redefined how America goes to war. The military isn’t using infrared because it doesn’t work. So how does a high-technology military tool apply to medical applications for breast cancer? It works like this: newly developing tumors require a constant blood supply in order to grow. As a tumor develops, it begins to recruit and create (angiogenesis) new blood supplies for the tumor. Years before that, the metabolic activity of tumor cells is higher and the growth rate is faster than that of surrounding cells. Each of these activities increases the amount of heat generated. Digital infrared technology has the ability to detect extremely small temperature differences (0.08°C). The military calls the infrared objects on the ground sensed from an aircraft a ‘heat signature’. Breast cancers also have a ‘heat signature’. Infrared imaging works because it exploits the Zeroth Law of Thermodynamics that has to do with thermal equilibrium. It is the same principle that is obeyed when your cup of coffee turns cold while sitting on a counter. Hot molecules migrate to colder environments in an attempt to equalize the temperature. Hot molecules in the coffee migrate into the ceramic cup and the table through conduction, and then into the air by convection - thus your coffee turns cold. Infrared technology records images of the small heat differences in objects. The Infrared Breast Imaging System The Infrared Breast Imaging System is a self-contained system and a simple procedure. The patient sits disrobed in a specifically designed chair, four feet from the imaging system with a built-in air cooling unit that puts out cold air directed toward the patient’s body. Small differences in temperature are picked up by the detector inside the camera (See figure 1). This Infrared Breast Imaging System is capable of detecting heat from a cancer as small as 1.5 mm, whereas the average size of a breast tumor identified by mammography is about 5 to 10 7
Figure 1: Digital Infrared Breast Imaging System
Visionary Breast Centers Business Plan 06.22.14
times larger. Dr. Bretz has seen in digital infrared breast imaging the ability to recognize the first signs that a cancer may be forming, years before mammography can detect it. After four minutes of infrared imaging, the results are immediately available. This system is completely computer automated, so there is no need for interpretation of the data. The artificial intelligence does the interpretation via the proprietary ‘neural network’ and the operator needs only basic computer skills (Figure 2 and Figure 3 are samples of the actual report format). This system eliminates many problems with current mammography: 1. 2. 3. 4. 5.
The need for highly trained specialty physician to interpret the imaging results The prolonged waiting period and the high anxiety prior to receiving the results The elimination of exposure to potentially harmful radiation Identification of breast cancer at its very earliest stages The need for extremely expensive equipment
The fact that infrared has no radiation (infrared just registers heat) means physicians can perform infrared imaging as often as deemed necessary to follow ultra-small breast cancers at no risk to the patient. The results of our first 500 infrared patients are consistent with our hypothesis that we can treat breast cancer in one day without traditional surgery, chemotherapy or radiation. Briefly, some of our important findings are: mammography had a false negative rate of about 24%. In our study we ordered 92 MRIs. MRI and infrared agreed 77% of the time, disagreed 23%. Of the 23% over time and using other studies infrared was proven correct in every case. Infrared in our study had a false negative rate of 0.4% and a false positive rate of 3%. 63 patients with a negative IR underwent biopsy because of another study indicating ‘suspicious for cancer’, usually mammography. Of those 61 were proved negative two were missed by IR. One was the fault of Dr. Bretz but was included. The sensitivity of infrared in our study was 96% and the specificity was 79%. We diagnosed 46 breast cancers (the smallest, 4mm) and 5 cancers outside the breast, 2 lung cancers, 2 CLLs cancers and 1 basal cell carcinoma of the skin. This potential will be researched further at VBC. One clinical study has been published in The American Journal of Surgery (2008) by Cornell University, and hopefully with proper funding more clinical studies are about to begin. One significant clinical study is currently being developed in cooperation with the state of California. It was submitted to the FDA by Dr. Bretz and has received a PRE IDE number #101175. The name on the trial is Condi-Waters Study and is meant to target indigent women who generally have no access to proper care. In addition, like no other trial it will actually employ these women to run the infrared studies giving them hope for the future.
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Figure 2: Sample Infrared Breast Imaging System Report (Page 1)
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Figure 3: Sample Infrared Breast Imaging System Report (Page 2)
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Digital Infrared Breast Imaging System The Infrared Breast Imaging System provides health care professionals with everything required to obtain infrared imaging data, analyze the data, recover meaningful physiological information from the data to support clinical judgment, and help physicians and patients make informed decisions. The IBI System facilitates screening evaluations for many different medical applications. The operation of the IBI System is simple through its Windows-based, graphic user interface (“GUI�), which allows an individual without any prior experience to learn how to operate the system in a single afternoon. The GUI is specially designed for ease of operation, and includes on-screen prompts, keyboard and mouse activated controls, as well as maximum hands-off program automation. System Components The system consists of a computer loaded with proprietary software, a FLIR infrared camera, an 8000BTU air conditioning unit, and a specially constructed chair. The patient sits in the chair, which is located approximately four feet away from the camera, and the camera takes a series of 3,000 images over a 4 minute period. Safe & Comfortable Test The Infrared Breast Imaging System is safe and comfortable. Unlike mammography, which emits potentially harmful radiation or x-rays, the infrared technology is purely passive and does not emit any harmful radiation. In addition, with the Infrared Breast Imaging System, the patient can sit comfortably and relaxed in a chair while the test is being performed. This is unlike the experience of mammography during which there is considerable compression of the breast, which can be extremely uncomfortable. Easy to Administer The Infrared Breast Imaging System is easy to operate. It can be administered by a medical technician, rather than requiring any input from a doctor or registered nurse. The system has been fully automated so that once the patient sits down the technician can start the test with several keystrokes. Within 30 seconds after completing the test, the computer produces a written report that specifically identifies any problem areas. Effectiveness of Infrared Breast Imaging System The Infrared Breast Imaging System test is extremely sensitive and accurate. Thermography has been known to detect signs of developing disease years before it develops into tumors. While this is true there is a difference between detection and localization. This has been a problem with IR current inability to precisely localize an abnormal focus for biopsy. We are confident we can overcome this with multiple cameras but requires further research. The Infrared Breast Imaging System can find tumors smaller than 4 millimeters. In a study of 110 known cases of breast cancer, the Infrared Breast Imaging System demonstrated a 99.1% detection sensitivity. This is much more effective than a mammogram, which many doctors believe fails to detect 20% of cancerous tumors in a major recent study. 12
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The Infrared Breast Imaging System provides a low cost, safe, non-invasive, adjunctive screening procedure for early detection of breast cancer. The Infrared Breast Imaging System has been demonstrated to detect breast cancer many years before conventional methods of screening in use today. Infrared imaging is a non-invasive technique completely free of the dangers associated with X-ray radiation or the physical discomfort of a mammographic procedure. The image generated by the Infrared Breast Imaging System is a graphic representation of data derived from the infrared energy emitted from the living breast tissue. The data is analyzed by sophisticated statistical algorithmic methods to detect abnormal physiologic activity within the breast, which may signal the existence of a malignant lesion or tumor. Preliminary studies have demonstrated the efficacy of high resolution dynamic digital infrared medical imaging with computer image enhancement and expert system interpretive software in the detection of breast cancer and other physiological dysfunction. One of the important biological characteristics of malignant tumors is that they develop their own blood supply, a process known as angiogenesis, and flourish in blood rich areas. The vessels that supply the blood to the tumor are not under the control of the sympathetic nervous system as are normal blood vessels. This means that the tissue supplied through angiogenisis does not respond to nervous system stimuli as would normal tissue. The Infrared Breast Imaging System takes advantage of this aberrant behavior to characterize the tissue in a particular area of the breast as "abnormal" and possibly the site of neoplastic activity or cancer. In the Infrared Breast Imaging System examination, cool air is directed over the breasts during an examination. Normal tissue will cool down at a regular rate because the sympathetic nervous system is calling for constriction of blood vessels to conserve core body temperature. New tumor blood vessels which result from recent angiogenisis do not respond to the sympathetic nervous system; consequently, the tissue supplied by those vessels continues to emit infrared energy at the same rate as before the cooling began. After processing up to three thousand images taken over a four minute period, the Infrared Breast Imaging System identifies, locates, and displays the areas of statistically significant abnormal infrared activity. The Infrared Breast Imaging System is intended to complement existing diagnostic methods in the near term. By comparing the processed infrared images of the breasts, the physician can objectively quantify whether there is statistically significant abnormal physiological activity within the breast. Based on clinical studies, tumors can be detected which are smaller than 4 millimeters. Refer to Exhibit B-1, which contains a paper that was published on the study results (IEEE, Engineering, Medicine and Biology Conference, 2003). The predecessor company has been gathering data for over many years and as additional clinical evidence is accumulated, the information provided by the Infrared Breast Imaging System has become the basis for an "expert system" which may assist physicians in making determinations of the need for further studies. Before any expert system can be relied upon in clinical diagnosis, government regulations require lengthy clinical trials. However, by using the Infrared Breast Imaging System as an adjunct to conventional X-ray mammography or ultrasonography, and leaving diagnosis to the physicians, regulatory issues are non-existent. The Infrared Breast Imaging System utilizes FDA approved Telethermographic imaging (21CFR884.2980 Class I device), as the basis for gathering physiological information from the patients breast. The Infrared Breast Imaging System was granted FDA 510k approval on February 20, 2004, for adjunctive use in breast cancer detection, and its European Union CE Mark on July 24, 2006.
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The Market
Fifty million mammograms are performed in the US alone. There are over 65 million women between the ages of 30-70 who are candidates for infrared imaging in the U.S. GICS will identify practice segments of physicians to receive the system free who meet certain specialization, geographic location and patient volume criteria. These doctors will not only have a ready base of imaging patients, but will develop a significant walk-in client “The Infrared Breast base of women seeking infrared imaging scans. The infrared Cancer Screening Tool is scan is currently “private pay” (paid for by the patient). Right already cleared by the US now a number of systems are already in use and generating FDA and has received revenue in the US and in Europe. Doctors are charging patients CE mark in the EU.” from $150 to $300 per scan, and the revenue to the company is $75 from each scan (billed as part of a $2,100 monthly operating lease). If 50 million mammograms were converted to infrared scans (at $200/scan) the market would be $10 billion dollars annually. Infrared breast cancer screening is directly applicable to approximately 70 million women in the United States and approximately 2 billion women in the developed economies worldwide. This equates to an annual $14 billion U.S. market and a $45 billion international market. Together China and India account for more than 1.3 billion women. Commercialization Strategy Our business strategy during the initial growth and adoption phase is to supply the imaging equipment free of charge to qualified doctors and Women 30-70 yrs Market Size facilities and charge a per70 million $14 Billion use fee. Doctors that U.S. receive an infrared breast Developed 225 million (estimate) $45 Billion imaging system sign a Countries contract to pay the company a minimum of $2,100 per month which equals $75 per scan on 28 scans per month (7 scans per week). For all scans above 28/month, $75 is paid to the company for each additional scan. This business model provides a significant incentive to the physician as they are capable of generating tremendous additional revenue for their practice. Physicians typically charge between $150 to $300 per scan and therefore they can add $75 to $225/scan to their revenue base. This equates to an additional $2,100 to $6,300 or more of income per month, or $25,200 to $75,600 annually for the physician. This takes place when doctors are desperate for increased revenue and are short on investment potential. The cost of the Digital Infrared Breast Imaging System is approximately $30,000. At higher volumes, the cost of each imaging system can be reduced to approximately $15,000. This expense to the company is recovered within approximately 1 year of the contract. All revenue for the Company beyond that point becomes straight profit. Making this model more attractive is the very low maintenance factor of IR. Service contracts for digital mammography machines run around $30,000 annually. After the initial adoption of these systems, the company will begin to lease the Digital Infrared Breast Imaging System in addition to charging a contract fee per test. The leasing plan will be at extremely low rates and will allow a physician to obtain the system for no money down. The small monthly payments would easily be covered by the gross profits on the test imaging income. During later phases of commercialization the company will seek medical insurance reimbursement. Third party reimbursement decisions are typically driven by clinical testing support for the procedure and the amount of patient and physician demand, in addition to FDA approval (which the company already has). Once insurance reimbursement is obtained, all women 14
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will have access to digital infrared screening for a small insurance co-pay. The initial target market for placement of these systems are the breast surgeon’s office, mammography screening clincs and OB/GYN offices. A growing number of foreign countries have expressed interest in acquiring these systems for breast imaging. The reasons surround cost for the unit itself, as mammography equipment and CAD systems can run between $500,000 to $1,000,000 per system including the cost of service agreements and consumables. This does not include the costs to employ trained radiologists. Also, the previously stated issues with mammography are major drawbacks to continued usage of this screening in developing countries. We intend to negotiate alternative pricing arrangements with foreign countries and alternative “per scan” fees. This will allow foreign markets access to this technology and provide this needed cancer screening tool to its citizens at an affordable price. Business Model Visionary BC is in the process of acquiring the assets and intellectual property, including the proprietary computer algorithms and software for this infrared breast cancer screening system developed over the past 10 years. The infrared imaging system has been approved by the FDA on February 20, 2004 and received its CE Mark in July 2006, thus clearing the way for sales in the US, the European Union, and many other countries around the globe. Once additional needed research is completed at VBC, patents can be filed. Studies have already demonstrated system’s clinical utility and sensitivity for detection of early stage breast cancer. Visionary BC will provide noninvasive high resolution digital infrared imaging for early breast cancer detection. The market need for this technology includes nearly every woman between the ages of 30 and 80 years old, as well as some high-risk men. Until there is a cure for breast cancer, the only effective defense is early detection. Visionary BC will have a proven non-invasive screening system that serves as a valuable adjunct to conventional breast cancer detection modalities, including Clinical Breast Examination (“CBE”), and which provides important information to doctors on overall breast health. Additionally, it has the potential to assist doctors in the decision making process and may prevent unnecessary biopsies. The Infrared Breast Imaging system (IBI), employs state-of-the-art digital infrared imaging to detect breast cancer with a high degree of accuracy and at a very early stage, together with other technologies like Halo. The product is an adjunctive test that physicians use to screen for and isolate pre-cancerous and cancerous tumors. The company provides the systems to gynecologists, radiologists, medical oncologist, hospitals, third-party imaging centers, and women’s health centers for use as an adjunctive screening tool to mammography or ultrasound. The Company’s research has shown that gynecologists and doctors of radiology of moderately sized practices can see up to 10,000 candidate women for the infrared imaging screening each year. This number increases significantly since that group is comprised almost entirely of women over 40 years old, while the Infrared Breast Imaging System is effective for women of any age. Since each procedure takes a maximum of 15 minutes, and there are at least 8 hours of use per day, up to 32 patients can be imaged in a day. Assuming 250 operational days per year, 8,000 Infrared Breast Imaging System screening tests can be performed each year, per system. Management’s financial projections assume only 1000 images per year (4 per day), per system and a $50 image-processing fee paid to the Company by the doctor. The doctor may also charge the patient the customary fees associated with clinical examination. Although the procedure will initially carry no insurance reimbursement, the Company’s experience with doctors and patients has shown that this is of little concern to them. Doctors 15
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recognize that the Infrared Breast Imaging System will substantially increase the cash flow of their medical practices. Employing management’s assumption of 1,000 images per year, an office with one system charging the patient only a $150 fee will generate additional annual income of $150,000 with no capital expenditure and no other additional expense. The system occupies only a total of 40 square feet of space, may be placed in a typical examination room and does not require a full-time or specially trained operator such as a radiology tech. The cost of the system is currently approximately $30,000, including installation and training. The table below demonstrates that with moderate usage every Infrared Breast Imaging System may recoup its cost in approximately six months. Unit Economics for Infrared Breast Imaging Tests per day 4 Revenue to Visionary BC per test $75 Revenue per day per system $300 Cost per system Days to breakeven
$30,000 100
The Company’s business model is intended to avoid the time and expense of selling expensive systems to doctors and seeks to capitalize on the volume of images to be processed. It also allows the Company to develop the market and to educate the medical community, without the attendant difficulties of selling a system based on complex technology that many healthcare providers may not yet understand. Once market demand is firmly established in the medical community, the Company will revise its strategy and no longer provide the Infrared Breast Imaging System free of charge. Future options include purchase by doctors or operating leases. There are over 20,000 gynecology and radiology centers in the United States. A medium sized practice will have 5,000 to 10,000 active patients. The Company targets large Gynecology and Internal medicine practices as well as Comprehensive Breast Centers. In addition, the Company also targets the following practices to expand its reach:
Type
Number of Potential Practices
Mammography Facilities OB/GYN Hospitals Imaging Centers Oncologists Dermatologists International
10,000 12,000+ 4,000+ 1,000+ 3,000+ 3,500+ >200,000
The primary means for screening for breast cancer is currently palpation, mammography and or ultrasound. There are approximately 50 million mammograms performed in the United States each year, typically on women over 50 years of age. Mammography is the primary means of screening women today. Once a tumor or lesion is found, other more expensive modalities, such as ultrasound, MRI, PET, CAT or biopsy, are used in a diagnostic capacity to determine if the tissue is cancerous. Currently even with these sensitive technologies the negative biopsies run about 500,000 per year. We will bring this unnecessary biopsy rate down melding our technologies. 16
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Many doctors and medical experts (and two recent major clinical trials) support the notion of screening younger women (twenty something) if there were a safe alternative to mammography. This conclusion is supported by two major studies. One by the American College of Surgeons published in 2009 and another by the Children’s Hospital of Seattle (2013). The ACS study advocated for starting mammography in African American women at around age 30 because they developed breast cancer at a younger age and usually it’s more aggressive. This as we know would have mammography looking at dense tissue in young women, not ideal. Since California adopted the new federal guidelines for mammography, that is no mammography below age 50 if the state is paying for it so we have a real moral dilemma. We could help this situation immensely if we accomplished a partially state sponsored clinical trial (which Dr. Bretz has). If California adopts IR screening for younger women the rest of the states would follow. IR is an alternative method to screen this sector of the population who is at risk. The Seattle study found that there is a dramatic increase in metastatic disease if younger women but again how to combat this brings us back to the problem of mammography in young women. The company will provide initial examination, surveillance and ongoing guidance to doctors joining our breast centers. Each doctor will have a team behind him or her. We will start and nurture The Society of Infrared Breast Imaging. Using a system considerably less sophisticated than the Infrared Breast Imaging System, a digital infrared study done at the Ville Marie Breast Center in Montreal, Canada, under the guidance of surgical oncologist, Dr. John Keyserlingk, has shown the effectiveness of infrared technology in a clinical practice. In this study, 100 women with Stage I and II breast cancer were examined. The identification accuracy rate of 84% with X-ray mammography alone was increased to 95% in conjunction with high resolution static infrared imaging. Dr. Keyserlingk notes that “mammography and ultrasound depend primarily on structural distinction and anatomical variation of the tumor from the surrounding breast tissue.” He contends that infrared imaging can display abnormal vascular patterns associated with the initiation and nourishment of malignant tumors. He further states “that when done concomitantly with mammography, infrared imaging can add valuable information, particularly in those patients with nonspecific clinical and mammographic findings.” The Ville Marie Breast Center study relied upon an infrared camera system in its most basic mode in which only single frame images were taken and then correlated with what is seen in a corresponding mammogram by a radiologist. The Infrared Breast Imaging System uses up to 3,000 such images and high speed computer processing to obtain substantially more information. This information can be presented in a series of images, ranging from the single frame used by Dr. Keyserlingk, to the computer generated images which includes displays of dysfunctional areas, vascular patterns, and other useful information. The predecessor company has conducted a series of clinical studies during the initial four years of development and has tested over 3,500 patients. To date more than 10,000 women have been tested. Included in our study group are 110 cancer cases, including three cases undetectable by mammography alone and which were found only upon ultrasound examination. Various types of malignancy were represented in this sample, including DCIS, LCIS, invasive ductal carcinoma, invasive lobular carcinoma, and inflammatory carcinoma; in some cases with lesions as small as 4 millimeters. In March, 2005 the Company commenced a clinical trial at the Cornell University Weill Breast Center, where the Infrared Breast Imaging System is undergoing rigorous evaluation. The Company has received approval by Yale University Medical Center to commence its clinical Study in June 2006, however this trial has not yet started. 17
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Finally, The University of Cambridge is conducting a study similar to Cornell as well as in another planned phase in monitoring neo-adjuvant treatment of breast cancer. The first phase of this Study commenced in April 2007. The Company believes that its clinical studies can be used to evolve a protocol which could lead to a significant decrease in the number of missed early breast cancers in the near future, and ultimately to the detection of cancer before any of the conventional modalities currently in use. Initially, the patient would be examined with OnncoVue and infrared imaging and her evaluation of risk would be calculated as either low or increased. A low score would be a strong indicator of the absence of breast cancer; however, for the near term at least, the patient would be instructed to continue with the diagnostic protocol. When an image with abnormal areas is generated, the patient would be given a mammogram with particular attention being paid to these sites. Any area of breast tissue which was not unequivocally cleared on the mammogram would then be subjected to ultrasound evaluation. It is highly likely that a program such as this, carried out with skilled radiology personnel in combination with the objective information obtained from the infrared examination, would significantly decrease the number of missed early breast cancers. Revenue Projection Commercial expansion and revenue generation will come through the placement of a large number of imaging systems throughout the U.S. We intend to market these systems through an outside sales force, of which several are well qualified to place and carry this product. Each system that is placed has the ability to provide a minimum of $2,100 per month of reoccurring revenue. The company’s cost per image is minimal if any, as these images are digital and requires no film or consumables for operation. A computer key code is provided to each center for the system’s continued operation. The system stops working after it reaches the preset limit of tests that are paid. New key codes are given, and this is how the company tracks the usage of each unit. As the placement of imaging systems increases, the company’s annual revenue and particularly its profit margins increase significantly. If needed, for cash flow purposes, we will contract with a leasing company that would provide the company advances on the annual scan fees from each center (advance on receivables). Our sales projections are derived from estimates of the U.S. market and foreign sales. In this pro forma, we have not accounted for opportunities to image and screen for other cancers as described in the later section of this document. POSSIBLE OPTION FOR PATIENT PARTICIPATION Basic Surveillance Membership - $300.00 A $900 savings if done individually Genetic results consulting and personal surveillance program for life set up Bi-annual breast exam Annual IR with consult Annual U/S, Elastography with consult Annual Halo if necessary with consult One free bone density if necessary One free laser treatment skin tightening, skin rejuvenating, etc. Intermediate Surveillance Membership - $600.00 An $1,800.00 savings if done individually Genetic results consulting and personal surveillance program for life set up 2-3 breast exams per year as deemed necessary 1-3 IR studies per year as deemed necessary 1-3 U/S, Elastography studies as deemed necessary 1-2 Halo studies as deemed necessary 18
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-
One free bone density if necessary Same day appointments 3 free laser treatments, skin tightening, skin rejuvenating, etc.
Advanced Surveillance Membership - $1,500.00 Genetic results consulting and personal surveillance program for life set up Unlimited breast exam as you and the doctor deem necessary Unlimited IR studies as deemed necessary Unlimited U/S, Elastography studies as deemed necessary Unlimited Halo studies as deemed necessary One free bone density One free needle aspiration of a cyst etc., if necessary 5 free laser treatments, skin tightening, skin rejuvenating, hair removal etc. Same day appointments Discount of $100.0 for another family member at the intermediate level Chronology: Acquire IR Company $250,000 Research to make it more user friendly then re-apply to the FDA for that change and apply for patents. start VBC as a crown jewel center (already started) 1-3 centers in Southern California Acquire other companies and or license OncoVue, Halo and SureTouch begin centers abroad in India and or China research new technologies such as_________(the possibility exists to develop a 3-D image of the breast such as a mammogram) and then actually voyage into that tissue using the _____ device. I call it the Breast Voyager. MANAGEMENT’S REVENUE PROJECTIONS (These are no longer applicable, need revision) The financial projections of the Company are estimated below.
Units Income Equip Leasing Interest Net Revenue Profit Margin General & Admin Sales & Marketing Dev & Clinicals Legal & Regulatory Acquire Assets
Series A $900K 2014 3 $75,600
Series B $5MM 2015 51 $1,285,200
2016 231 $5,821,200
2017 711 $17,917,200
2018 1431 $36,061,200
2019 2511 $63,277,200
2020 3831 $96,541,200
$12,600
$214,200
$970,200
$2,986,200
$6,010,200
$10,546,200
$16,090,200
$63,000 83%
$1,071,000 83%
$4,851,000 83%
$14,931,000 83%
$30,051,000 83%
$52,731,000 83%
$80,451,000 83%
$205,000
$660,000
$955,000
$965,000
$1,000,000
$1,030,000
$1,045,000
$60,000 $25,000
$706,780 $190,000
$1,718,180 $190,000
$4,007,580 $190,000
$7,224,180 $190,000
$11,886,580 $190,000
$17,331,180 $190,000
$60,000 $500,000
$75,000
$95,000
$95,000
$115,000
$115,000
$165,000
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Transfer Assets Net Income
$15,000 -$802,000
-$560,780
$1,892,820
$9,673,420
$21,521,820
$39,509,420
$61,719,820
These figures did not take into account the recent financial problems of virtually every company. An approximate need for cash to acquire these companies is outline below. Dr. Bretz has personally engaged these companies and they are willing to engage in acquisition talks. OncoVue Infrared Halo Pressure device See figures next two pages. While these figures are approximate they are close and we need to acquire these companies to move forward with vast potential. Why these companies are all financially strapped through no fault of the technology. For example, there is a new journal out called Genomics. The editor-in-chief was quick to point out in the inaugural issue that the advanced potential to better patient care will go nowhere without mainstream providers learning and embracing this new frontier. Competition The demand for improved technology in the area of early breast cancer detection is overwhelming. Positive initial physician adoption of these imaging systems confirm a belief in the product and the obvious market need. Patients are also anxious to have the test, as there is no other non-invasive physiological test available today. The medical literature supports the need for physiological tests in the detection of breast cancer and the monitoring of clinical response to treatment. The goal of the company is to become synonymous with early breast cancer detection and to save countless women’s lives. Competition in the area of screening for breast cancer is very limited. The one competitor we are aware of is No Touch Breastscan which appears to have started offering its systems in 2009 and seems to be focused on international countries. It is unclear who they are targeting and what their business model is for placement of their systems. We believe they are not interested in melding technologies or trying to change breast care globally just selling random systems. VBC has been opened to change the paradigm. There are numerous clinics that have purchased infrared cameras and are offering thermography, but there is a significant need for a self-contained, automated, and computer controlled software driven system that can interpret the results. There is substantial research being conducted by the major pharmaceutical companies and others who are attempting to find a cure for cancer. If an effective compound or medicine is eventually discovered, the Company believes that it would not be detrimental to its business model because patients would still require screening to determine if they have cancer. Another important note on the competitive landscape: while mammography is currently the standard of care for breast cancer screening, many doctors have ceased offering mammography since they lose money on the procedure.
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The table below summarizes the competitive environment. Breast Cancer Screening Competing Technologies Provider Efficacy Cost Notes
Technique Infrared Self Exam Palpitation Mammography Ultrasound Laser Impedance MRI PET Nuclear Biopsy
Visionary BC Self doctor Gen. Elec. (GE) Sonosite (SONO) Imaging Diag. (IMDS) Mirabel Medical Various Various Various Done by doctor
Very High Low Low High Medium Unknown Unknown High High High Highest
Low None Med. Med. Med. NA Medium High High High High
Excellent results and profitable for doctor Cannot detect tumors at early stages Done at OB/GYN; misses small tumors Not effective with women 20-50 yrs. Not good for DCIS No FDA; for diagnosis not screening Not easy to use High cost; for diagnosis not screening High cost; for diagnosis not screening High cost; for diagnosis not screening Very invasive; for diagnosis not screening
Follow-on Applications Worldwide over 1,250,000 people are diagnosed with cancer and over 500,000 die each year. The company has identified multiple additional opportunities for use of Digital Infrared Imaging Systems to detect other types of cancers. These cancers provide tremendous opportunity for significant need where there are no good screening tools available. In addition, several of these types of cancers have already been detected by the Company using the existing Infrared Breast Imaging System, though the existing system in its current configuration is not intended to screen for these types of cancers. These opportunities include: •
Screening for Lung Cancer
•
Screening for Pancreatic Cancer
•
Screening for Ovarian and Uterine Cancer
•
Imaging in the ER for internal bleeding with trauma patients
•
Imaging for large animals such as in the race horse industry
•
Screening for identifying malignant skin cancers
The opportunity and number of other applications for the use of this infrared technology are tremendous and could greatly exceed the total market opportunity of imaging for breast cancer alone. These will be researched. Intellectual Property The assets the Company will be acquiring including filing a patent application with the United States Patent and Trademark Office for the Infrared Breast Imaging System and software. The core of the intellectual property is the software and know-how, which has evolved over more than nine years of development and testing. The Company believes that key differentiators for this medical device system is its unique software algorithm and neural network learning capabilities.
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Acquiring the Core Technologies OncoVue™ Genetic Testing – Estimated approximately $5 million for an outright acquisition including all assets and patents and hire personnel and get CLIA certified. Pressure Sensing Technology – This involves two companies (laptop and hand held) each estimated approximately $1 million for assets and patents. Digital Infrared Imaging – This has been acquired by GentestIR and is now an asset of GentestIR value estimated approximately $1 million Halo – Estimated approximately $3 million should enable GentestIR to either acquire Halo outright or controlling interest or close to it. The letter from their CEO indicates they only have three employees and they are on a respirator. Aura is an exam they developed that can detect breast cancer down to the cellular level. It was developed by Halo however they didn’t have the funds to exploit it. We will. The total for acquisition of these companies is estimated approximately $10-$12 million. An estimated operating capital requirement of approximately $5 million will be needed for operating capital, setting up additional Visionary Breast Centers in other locations and overhead to reach profitability. Investment Opportunity and Potential Returns This is open to discussion depending on amount invested which will buy a specific amount of GentestIR stock. See GentestIR below. Next Steps and Plans The Visionary Breast Center Protocol and Procedures have been utilized by Dr. Bretz for the past 6 years with amazing results. Currently he has done six cryoablation procedures at the institute with the patient resuming normal activity immediately the procedure is called The Lavender Procedure. In order to capitalize on the success of this effective protocol it needs many of the technologies to be acquired before implemented in additional VBCs. Before VBC can become operational, IR needs to be refined as a more user friendly unit. The same can be said for the pressure device. Dr. Bretz has contacts that can provide the IR expertise to change the software and then apply for a patent under GentestIR. GentestIR is a newly formed company by Dr. Bretz and Dr. Borko Djordjevic (Dr. Bretz’s long time associate who is a renowned plastic surgeon). GentestIR is meant to manage the acquisition and implementation of the various technologies and conduct new research like the Breast Voyager. Further, GentestIR has coupled with CALSEC located in Irvine, CA. CALSEC have developed a vehicle/devise that detects IEDs and have a contract with the Pentagon and also a contract to provide surveillance for the upcoming Olympics in Japan. They also have contracted work with Hitachi. Please Google Calsec.com. CALSEC’s CEO is Mr. Maglich who has overseen the world’s first sub-nano technology. CALSEC has a fulltime physicist on board and space for VBC to conduct the necessary research. It is possible that CALSEC may go public in the near future perhaps not. GentestIR is in discussions with CALSEC concerning a probable synergistic association. We need to resurrect these companies. At least one center here in the U.S. will be necessary preferable 3-5. The flagship center will serve not only as a flagship to provide data but to be an educational center for doctors all over the world to attend educational research and certification courses. 22
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However, to provide income to the stockholders of GentestIR centers can be opened in either India or China where Dr. Bretz has substantial contacts who are ready to go upon VBC being operational. In fact the contact in India has about 500 health care centers in Southern India. It would be anticipated to start small (perhaps 3-5 centers) educating every doctor and Dr. Bretz going there to help the learning process. Data will be collated from all the centers to produce ongoing massive results used to build other centers on other countries. Once this new paradigm is proved beyond everyone’s shadow of a doubt the U.S. will have to incorporate it in every state and it will be covered by insurance. The overriding problem is that every company (except for the Hitachi U/S) is basically out of business some functioning only on paper and shut down, one functioning with only three employees. It is not that the technologies don’t work or anything of the kind. They work just fine if given the chance. They were basically startups back around 2005. This is also the time where universal pressure on doctors with less reimbursement and ever more regulation was heaped on them. Many doctors have just retired or planning to cut way back on hours because it isn’t fun anymore and government functionaries have made it near impossible to provide necessary care. All Dr. Bretz has seen is increasing denial and delaying of care. As a consequence of this doctors are not sure if they will be in business in a year let alone learn and invest in new technologies. These findings coupled with being outside the mainstream have made it virtually impossible for these companies to prosper. We will change the entire paradigm of how doctors acquire state-ofthe-art technology making participation easy. The technologies will be installed without charge and GentestIR will receive a portion of the revenue intake to be defined by the board of GentestIR. With the down turn in the economy in 2008 still lasting and with the implementation of Obama’s surcharge on new technologies at the point of sale (2.5%), some say spelled the death knell for these good companies through no fault of their own. We believe we have the right formula to not only prosper but carry this project around the world and save millions of lives in the future if these companies are restored. VBC’s mantra is ‘personal breast care for life’. The idea is that a young girl in her late twenties comes in to start an individualized surveillance program based on the genetics test. She is then followed doing whatever tests are indicated as often as necessary. Because most of the technologies involved are not yet covered by insurance VBC will be all cash thus the various membership opportunities. There will be different categories a woman can participate in such as basic, intermediate and advanced. Each level will carry with it additional perks such as free laser treatment for skin tightening etc. The message will be if you come in early and we follow you, we will try and prevent any breast cancer by active prevention and if not find the cancer when it is so small it can be treated without traditional means and have an excellent outcome. That is no down time, no disfigurement, no bankruptcy, no fathers that leave because of the mastectomy and most importantly no deaths. Bingo. What do we need? .
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MANAGEMENT AND KEY PERSONNEL Set forth below is certain information concerning the executive officers, directors and other key employees and advisors of the Company. Additional staff are targeted to be added as funds are raised. Name
Age
Position
Philip Bretz, MD………………..68
Chief Medical Officer
Craig Shimasaki, PhD, MBA…. .56
Executive and Entrepreneur-in-Residence, Business and
Scientific Strategy
BG (US Army Ret) Richard Lynch, D.O…70 Chief of Imaging VBC David Mantik, M.D., PhD…..73
Director of Radiation Therapy
Borko B. Djordjevic, M.D., PhD…70 Co-founder GentestIR Phil Bretz, MD Chief Medical Officer
Dr. Phillip Bretz is a dedicated breast cancer surgeon and researcher. He was born in Chicago in 1945 attended North Park University and did his surgical training at Loyola University in Maywood, Illinois. He is founder and director of Visionary Breast Centers and co-founder of GentestIR. Briefly, he founded the first comprehensive breast center in the Coachella Valley and one of the first in the United States, 1988 the Desert Breast Institute. Since then he has cared for well over 12,000 women and publishes his results in peer reviewed journals as well as invited presentations around the world. His mantra is to preserve mind, body and spirit, something he doesn’t take lightly. He has continually refined his approach to diagnosing and treating breast cancer to where now we can accomplish the diagnosis without radiation at about 3-5mm and treat the cancer without the need for traditional surgery, chemotherapy or radiation. This will make a difference in the world. In knowing about him, we have included his CV and a memorandum from Dr. Janet Vargo, Director of Translational Research for Johnson and Johnson. This was unsolicited and says it all from a renowned peer. His surgical career spans over 30 years and includes being an integral part of the open heart surgical team at Eisenhower Memorial Hospital in Rancho Mirage, CA where the team did over 4000 open heart procedures (having the lowest mortality rate in the country as verified by Medicare 1983 and 1984) and he was the assistant surgeon on First Lady Betty Ford’s 24
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heart surgery. He has carried a principal investigator number 17790 from the National Cancer Institute for over twenty years. Aside from being the designated surgical liaison for the American College of Surgeons he served as Chairman of the Cancer Committee at Eisenhower and was first to bring National Cancer Institute clinical trials to the Coachella Valley. At Eisenhower he was the designated principal investigator for the National Surgical Adjuvant Breast Project (NSABP) the largest breast cancer research group in the country. He also served as a civilian physician aboard the Marine Air Ground Combat Center at 29 Palms for four years. Along the way he was a principal speaker on President HW Bush’s Breast Cancer Panel and was awarded the Carnegie Medal for heroism as well as two medals of excellence given by the commanding general of the 332 medical brigade. In addition, he has been recognized multiple times for his excellence in pioneering medical technology by FLIR (Forward Looking Infrared a fortune 500 company). FLIR supplies our military branches with IR technology. For him, his significant achievement in research is being the author of our country’s first large scale breast cancer prevention clinical trial (working with the erstwhile Soviet Union) using the drug Tamoxifen, FDA IND 34,223. He wrote a 400 page book on this experience called, Sacrificing America’s Women. He has developed and published a unique surgical procedure to augment accelerated partial breast radiation and over the past six years has done the ground breaking research on the five technologies necessary to reach our goal. He has been married to his wife Joan for 45 years and together has raised four productive children. He will serve as Chief Medical Officer and Chief of Surgery.
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www.desertbreastinstitute.com PHILLIP D. BRETZ, M.D. CURRICULUM VITAE 2014 ¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬ Born: October 25, 1945 – Chicago, Illinois Current Position: Founder/Director – Desert Breast and Osteoporosis Institute, Inc. Established 1988 – 12,000 patients seen as of January 4, 2010 Business Address: Desert Breast and Osteoporosis Institute Inc. 78-034 Calle Barcelona Ste B La Quinta, California 92253 Ph: 760-771-4939 Fax: 760-771-4749 e-mail: TamDoc@aol.com Home: La Quinta, California 92253 Marital Status: Married 44 years to Joan V. Bretz Children: Jason (40), Ashley (37), Christian (32), Alexandra (25) --------------------------------------EDUCATION-----------------------------------University: North Park University and Theological Seminary - 1963 -1968 3225 W. Foster Avenue Chicago, Illinois 60625-4895 Ph: 773-244-5728 Double Major - Biology/Psychology Degree Awarded: BA Biology Laboratory Instructor Letter Swim/Track Team Medical School: Universidad Autonoma De Guadalajara - 1969 - 1973 Guadalajara, Jalisco Mexico Degree Awarded: M.D. Internship: College of Medicine and Dentistry of New Jersey - 1973 - 1974 New Brunswick, New Jersey, Rutgers Medical School Muhlenberg Hospital - Plainfield, New Jersey Chairman: Paul Johnson, M.D. Rotating, Fifth Pathway
---------------------------EDUCATION CONTINUED-------------------------26
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Surgical Residency: Loyola University Medical Center/Hines Veterans Hospital 3150 S. First Avenue Maywood, Illinois 60153 Ph: 708-216-9000 Straight General Surgery - 1974 - 1979 Chairman: Robert J. Freeark, M.D. Chief Surgical Resident - 1979
The
Certification: Basic Science Board - State of Iowa, No. 16,032 - 1972 Flex Exam: Federal licensure exam No. 01855568 - 1978 American Board of Surgery - Part I, 1988 - Board Eligible 2008 X-ray Supervisor and Operator, State of California No. RHC 131271 – 1989 Certified for planning and placement of Mammo-site (accelerated partial breast radiation) device, 2004 Hologic QDR 4500 DEXA - Operators Certification No. 45859 - 1999 Facility certified the first attempt by the American College of Radiology, State of California and the FDA in 2003 Certified in ELOS Laser technology 2006 Certified in Infrared Breast Imaging 2006 Infrared Level 1 certified by FLIR, March 07 Licensure: State of Illinois - 36-55297 – 1978 - Unrestricted - Inactive/Expired State of California - A32596 - 1978 - Unrestricted - Active DEA - AB 8815170 ----------------------------SOCIETY MEMBERSHIPS--------------------------Past and Current American Medical Association
ISCD International Society of Clinical Densitometry
California Medical Association Riverside County Medical Association
American Society of Breast Disease
IntraAmerican College of Surgeons – Fellow Society of Minimally invasive Therapy American Society of Abdominal Surgery - Fellow Flying Physicians Association
SPIE
Charles B. Puestow Surgical Society - Past President American Society of Parental and Enteral Nutrition Aerospace Medical Association – Space Medicine Branch ----------------------------------APPOINTMENTS---------------------------------Eisenhower Medical Center - 1979 - 2009 27
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39000 Bob Hope Dr. Rancho Mirage, California 92270 Ph: 760-340-3911 Active Surgical Staff - Unrestricted privileges for thirty years Heart Institute of the Desert - 1981 - 1989 39600 Bob Hope Dr. Rancho Mirage, California 92270 Ph: 760-32-HEART(closed 2000) Associate Surgeon, Open Heart Surgical Team Naval Hospital 29 Palms - 1990 - 1995 Marine Air Ground Combat Center 29 Palms, California 92278-5008 Ph: 760-830-2354 Civilian Emergency Room Physician National Surgical Adjuvant Breast Project - (N.S.A.B.P.) - 1990 - Present East Commons Professional Building Four Allegheny Center - 5th floor Pittsburgh, Pennsylvania 15212-5234 Ph: 412-330-4600 Principal Investigator - active NCI sponsored research protocols National Cancer Institute (NCI) - 1990 - Present National Institutes of Health National Cancer Institute Division of Cancer Treatment and Diagnosis Bethesda, Maryland 20892 Ph: 301-496-5725 Clinical Investigator - active - No. 17790 Desert Breast and Osteoporosis Institute - 1988 - Present 78-034 Calle Barcelona Suite B La Quinta, California 92253 Ph: 760-771-4939 Founder/Director Senior Surgeon Mirage Surgical Center - 1996 – 1999 then closed 39935 Vista Del Sol Rancho Mirage, CA 92270 Ph: 760-779-9951 Active Surgical Staff - Unrestricted Privileges American College of Surgeons Oncology Group (ACOSOG) Member number 9472, group #450 - 2006 ------------------------APPOINTMENTS CONTINUED------------------------Hope Square Surgical Center - 1998 - 2004 39700 Bob Hope Dr. Suite 301 28
Visionary Breast Centers Business Plan 06.22.14
Rancho Mirage, California 92270 Ph: 760-346-7696 Active Surgical Staff - Unrestricted Privileges American College of Surgeons - 1985 Commission of Cancer Field Liaison Officer Desert Breast Foundation 501©(3) Public Benefit Corp. (founder) 2002 SJ Medical (Family Practice) San Jacinto,CA. Locums position June 2010-Present ---------------------------------------AWARDS---------------------------------------(2) United States and Foreign Patents - #5,500,017 and # 6,932,840 – Honey Breast Implants and the first triple breast implant sac. Go to www.uspto.gov and hit search and put in #’s Carnegie Medal for Heroism Recipient – 1992, www.carnegiehero.org , (click on search awardees and put in my name) Carnegie Hero Foundation 425 Sixth Avenue Pittsburgh, Pennsylvania 15219-1823 Ph: 412-281-1302 California Highway Patrol Riverside County Certificate of commendation - 1992 Brigadier General R.H. Sutton, Commanding General Marine Air Ground Combat Center 29 Palms, California 92278-5008 Letter of Commendation - 1993 Honorable Pete Wilson Governor, State of California Letter of commendation - 1993 Embassy of Union of Soviet Socialist Republics Letter of Appreciation - 1990 Academy of Science Ukraine Republic Letter of appreciation - 1990 Secretary of State of the United States of America Honorable James Baker III Letter applauding Dr. Bretz’s efforts to forge a joint U.S./U.S.S.R. breast cancer prevention project - 1990 ------------------------------AWARDS CONTINUED-----------------------------President Gerald R. Ford Letter of appreciation for services rendered - 1985 Dr. T. Burton Smith 29
Visionary Breast Centers Business Plan 06.22.14
White House physician under President Reagan Letter of commendation - 1985 Department of the Navy Capt. CS Chitwood, Commanding Officer Naval Hospital 29 Palms, California 92278-5008 Letter of appreciation - 1993 Brigadier General Richard D. Lynch Commanding General 332nd Medical Brigade, United States Army Reserve Commander’s award for excellence – 1999, 2000 Consumers’ Research Council of America, “Guide to America’s Top Surgeons” 2008 ---------------------------PROFESSIONAL ACTIVITY-------------------------Chairman Cancer Committee - Eisenhower Medical Center - 1982 - 1985 Medical Research Committee - Eisenhower Medical Center - 1990 - 1991 Surgery Committee - Eisenhower Medical Center - 1981 - 1983 Chairman - American/Soviet Combined Effort to Defeat Breast Cancer - 1990 Chairman and Author - “A Clinical Trial to Determine the Worth of Tamoxifen in the Prevention of Breast Cancer” - 1990 - This was America’s first large-scale breast cancer prevention project, presented at the FDA Open Hearing, Bethesda, MD - June 1990. Our concept was unanimously passed by the FDA Advisory Panel. Joint work with the Institute for Ultra-fast Spectroscopy and Laser Mammography, New York University CCNY - Robert Alfano, Ph.D., Chairman - 1992 - Present Principal Speaker - President Bush’s Breast Cancer Panel - “Revolutionizing Breast Cancer Treatment Now For The Twenty First Century,” Atlanta, Georgia - 1993 Office of Environmental Health Hazard Assessment - State of California Principal Speaker - (Hearing), “Tamoxifen as a Cancer Causing Agent” Sacramento, California - 1995 An Autologous Abdominal Free-Fat Patch Surmounts the Problem of Skin Spacing During Accelerated Partial Breast Radiation (APBR) – presented November 09 at ASTRO this is a review of our experience with APBR to date and the Fat Patch ------------------PROFESSIONAL ACTIVITY CONTINUED---------------Author and presenter (including poster session), of “The Compass Treatment: A New Era of Treatment in Breast Cancer Neoadjuvant Therapy and Radiation without Surgery,” presented at the 5th Annual Multidisciplinary Symposium on Breast Disease February 13-16, 2000 Rome, Italy Author and oral presenter of “Using Primary Chemotherapy to Treat Breast Cancer Without Demonstrable Metastases to Identify Responders to Minimize or Avoid Surgery”(the 30
Visionary Breast Centers Business Plan 06.22.14
Desert Breast Institute experience), presented at the World Conference on Breast Cancer, July 1997, Kingston, Ontario, Canada. Also presented at the First International Meeting on Advances in the Knowledge of Cancer Management, Vienna, Austria - July 1997. Published in Volume 16 Program/Proceedings American Society of Clinical Oncology, 33 Annual Meeting, May 1997, Page 163a Author - “Minimizing or Eliminating the Role of The Surgeon in the Treatment of Invasive Breast Cancer, is Now The Time?” presented at The Society For Minimally Invasive Therapy London, England - September 1998 Co-author “New era of treatment in breast cancer – Neoadjuvant therapy without surgery,” European Journal of Cancer, Vol 34, 1998 page 488 “The Bretz-Stevenson Patch” – An Autologus Abdominal Free Fat Patch Transfer to Surmout the 7mm Skin Barrier in using A Partial Breast Irradiation Device (APBI), with editors The American Journal of Surgery, 2007 Principal Investigator – Protocol No. IGI-103: “Assessment of OncoVueTest Risk Perception and Behavior,” Sponsor – InterGenetics Inc. Advanced breast cancer risk test. Oct 2006, closed 3/08 and FDA approved. Supplied 530 patients. Distinguished speaker - Eisenhower Medical Center, Annenberg Center For Health Sciences - 1995 ----------------------------RESEARCH PROTOCOLS---------------------------“A Clinical Trial To Determine The Worth Of Tamoxifen In The Prevention Of Breast Cancer” presented to the FDA Advisory Panel Open Hearing, Bethesda, MD - June 29, 1990 “A Clinical Trial To Determine The Worth Of Laser Mammography In the Diagnosis And Treatment of Ultra-small Breast Cancers With Or without Tamoxifen” presented to the Institute for Ultra-fast Spectroscopy and Laser Mammography, CCNY - 1991 “A Clinical Study to Determine The Physical and Psychological Impact Of Free Silicone Breast Injections” - 1994 “A Clinical Trial To Determine The Worth Of Honey As a Safer And Cosmetically Superior Alternative To Saline/Soy Used Breast Implant Material”, presented to FDA 1996, (see business plan for Absolute Breast Solutions, Inc.), June 1998 ‘Breast Cancer in Tough Economic Times Disruptive Technology Emerging – SPIE 2012 --------------------------RESEARCH PROTOCOLS CONTINUED --------------------------“A Clinical Trial To Determine The Worth Of Tamoxifen In Preventing Radiation Induced Breast Cancer in Chernobyl Survivors” presented to the Minister Of Health Ukraine, Kiev U.S.S.R. – 1990 “Surmounting the 7mm barrier of skin spacing using MammoSite Partial Breast Irradation Device, presented April 27, 2006 at the American Society of Breast Disease World Congress, Las Vegas, Nevada - Principal Author and poster presenter
31
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NSABP Protocol B-18: A Unified Trial to Compare Short Intensive Preoperative Systemic Adriamycin-Cyclophosphamide Therapy with Similar Therapy Administered in Conventional Postoperative Fashion 1989 - current (still following patients) NSABP Protocol B-21: A Clinical Trial to Determine the Worth of Tamoxifen and the Worth of Breast Radiation in the Management of Patients with Node-Negative, Occult Invasive Breast Cancer Treated by Lumpectomy 1989 – current (still following patients) Principal Investigator: A Study of TRIAB (11D10) and CEAVAC (3H1) Anti-idiotype Monoclonal Antibodies in Combination With First Line Hormonal Therapy For Patients With Metastatic Breast Cancer, a breast cancer vaccine trial (underway) 2001 Titan Pham Chairman and Author: “The Condi-Water’s Study”- A Randomized Clinical Trial to Compare Three Emerging Diagnostic And Therapeutic Modalities to Standard Modalities For Breast Cancers 8mm or Less With or Without An Aromatase Inhibitor, FDA IDE Submission Oct, 2006. In- Progress. This study will seek to answer the question whether we can select high-risk women with a new genetics test (OncoVue), follow them with digital infrared and treat cancers found in one day without chemotherapy, surgery or radiation using cryoablation. Chairman and Author: “The Soft Breast Lift Trial”- Foto Laser Tightening Trial, A Randomized clinical Trial to Compare The Worth Of Non-surgical Bi-polar Radiofrequency/Laser Energy To Conventional Surgery For Lifting The Breast. To commence Oct, 2006 ----------------PUBLICATIONS REFERENCING MY WORK-------------American Society of Breast Disease, Las Vegas April 06, Poster 2-24 The Breast Journal, September/October 2000 Volume 6, Number 5, page 349 Journal Of American Society of Clinical Oncology, 33rd Annual Meeting Scientific Proceedings, abstract No. 569, Subject Indexes page 46, Denver, Colorado - May, 1997 UICC Cancer Management Meeting, abstract No. 135, page 38 Vienna, Austria - July 1997 World Conference on Breast Cancer, Program page 23, Kingston, Ontario, Canada July 1997 Current Clinical Trials Oncology, National Cancer Institute PDQ, page P-23 July/August 1997 ---------PUBLICATIONS REFERENCING MY WORK CONTINUED---------Medical Tribune, “Tamoxifen Trial Under Fire” by Marjorie Shaffer, April 1992 Los Angeles Times, “U.S., Soviets Plan Study of Breast Cancer Prevention” by Michael Parks, March 2, 1990, also “Debate Swirls Over Breast Cancer Drug” by Paul Jacobs, November 8, 1995 Vogue Magazine, “With Survival Rates Unchanged And More Women Diagnosed Every Year, Breast Cancer Prevention Is The Next Frontier,” by Susan Ince page 278-286, October, 1990
32
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CNN, special three part series covering the Desert Breast Institute, the open FDA hearing and breast cancer politics, by Jeff Levine, July 1990 North Parker (a magazine for alumni and friends of North Park University) an article covering Dr. Bretz’s career, pages 18-19 and 30, winter edition 1999 KMIR-TV. NBC affiliate, multiple appearances KESQ-TV, ABC affiliate, multiple appearances Uspto.gov and put in my patent # 5,500,017 or # 6.932,840 “American Politics 1996” (a book on American Politics) see State of California under 44th Congressional District The Cancer Letter, a Washington based journal covering cancer news, see article covering breast cancer prevention, 1990 The Desert Sun (newspaper) multiple front page articles The Press-Enterprise (newspaper) multiple articles by Michael Schwartz ---------------------------------OTHER ACTIVITY--------------------------------FAA - private pilot certificate, issued 1967 Founder, “Keeping a Breast,” a women’s breast cancer support group at the Desert Breast Institute Specially called White House meeting with the Honorable Dennis Ross, (President Bush’s Chief Domestic Policy Advisor), covering breast cancer prevention, 1992 Participant, Human Resources and Intergovernmental Committee’s investigation into the NCI sponsored Breast Cancer Prevention Trial (BCPT), 1992 Congressional Record, October 1990 by Congressman John Meyers ®, Indiana ---------------------------OTHER ACTIVITY CONTINUED---------------------------Republican Congressional Candidate, 44th Congressional District, State of California, June 1994 on the ballot Author, “Sacrificing America’s Women,” a 400 plus page non-fiction book which takes a critical look at the BCPT and reasons behind our country’s failure to defeat breast cancer, 1996 Author, “The Second Declaration on Independence,” fiction, in progress 2005 Cub Scout Leader, Inland Empire Council B.S.A., Riverside County, Pack 79, 1984 ---------------------ADVISORY BOARDS/CONSULTANT---------------------33
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Shire Pharmaceuticals
Merck and Co.
Proctor and Gamble
Novartis
Veridex -----------------------SPECIAL ADVANCED RESEARCH------------------The New York Center for Advanced Technology in Ultrafast Photonics City University of New York, Directed by Robert Alfano, is establishing a NIH (National Institutes of Health) network for Translational Research: Optical Imaging (NTROI) with an emphasis on breast imaging. We intend to include in-vivo imaging of molecular events in cells and search for pre-cancerous lesions. Invited member of the consortium research -234group including University of Pennsylvania, Memorial Sloan Kettering Cancer Center and Washington University (St. Louis) among others – February 2003, funding pending Invited founding Advisory Committee member NTROI – 2003, 646-312-2220 pending funding still ¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬ ----------------------------------------------------------------------------------------------------------------Ongoing Infrared and Genetics study Oral presentation and published at “Inframation” The world’s largest infrared conference, Oct 2010, LasVegas, NV Breast Cancer in Tough Enonomic Times. Published in InfraMation 2010 Proceedings pages 435-448. A critical look at our first 500 Infrared and genetics patients. SPIE Defense and Security Conference, Baltimore April 2012, (invited paper) and oral presentation on The First 500 Patients using Infrared and OncoVue. THERMAL IMAGING CONFERENCE San Diego, June 3-6, 2013 (invited paper) and oral presentation on ‘Visionary Breast Centers’.
----------------------------------------HOBBIES--------------------------------------Cycling Book and Screenplay Writing Fishing, Northern Pike, Lake Trout, Northern Manitoba, Canada Skeet Shooting 34
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Golf Weight Lifting Astronomy Appearing in independent films by my son Jason, awarded Director’s Guild presentation Hollywood, California, 1997-98 “Fatherland” Inventing - lure design, breast aids, potty handle (pat. pend), kitty cabana (pat. pend), surgical instrument for improving the Ramstead procedure, laptop security device, new breast implant device (patent awarded, 1996 and 2005), potting soil container RE/MAX World Long Drive Championship, participant 2002, senior division 305 yds. Rode with Lance Armstrong and others 50 miles in the 2005 Tour of Hope into Washington, DC, October 8, 2005 can go to Tour of Hope.org or www.active/donate/dcride/lafPBretz Tour de Palm Springs - century ride – February 11, 2006 Camp Pendleton Challenge – century ride, April, 2006 Shadow Tour – century ride – May, 2006 Independent film “How to Be EMO” directed by Christian Bretz, played scientist, visit www.whatsemo.com Craig Shimasaki, PhD, MBA Executive and Entrepreneur-in-Residence, Business and Scientific Strategy Dr. Shimasaki serves as Executive and Entrepreneur-in-Residence. He is President & CEO of BioSource Consulting Group, a strategic consulting firm that assists biotechnology organizations in effectively translating their idea to commercial products. He is currently President and CEO of Moleculera Labs, a CLIA-certified and COLA-accredited clinical laboratory that tests children for treatable neuropsychiatric and autoimmune disorders. He was previously co-founder, President & CEO of InterGenetics Incorporated, a genetic-based breast cancer risk assessment company, he continues to serve on their Board of Directors. Dr. Shimasaki serves on multiple boards including past appointment to the Governors’ Science and Technology Council. Dr. Shimasaki is co-founder of two other biotechnology companies and has over 25 years of biotechnology business and scientific experience in developing and commercializing biotechnology products. He has participated in raising over $50 million dollars for these companies including taking one public through an IPO. He has held multiple roles in these organizations including VP of Research & Development, Chief Operating Officer, and President & CEO. Dr. Shimasaki has led 5 products through the FDA to obtain successful marketing clearances and he has led multiple international clinical trials for several biotechnology products. He is an inventor on numerous patents for infectious disease diagnostics, genetic-based tests and medical devices and he has published authored/edited two books, one titled “The Business of Bioscience: What Goes Into Making a Biotechnology Product” and another titled, “Biotechnology Entrepreneurship: Starting, Managing and Leading Biotech Companies.” Dr. Shimasaki completed his BS in Biochemistry from the University of California, Davis, a Ph.D. in Molecular Biology and Biotechnology from the 35
Visionary Breast Centers Business Plan 06.22.14
University of Tulsa, and an MBA from Northwestern University’s Kellogg Graduate School of Business. BIO RICHARD LYNCH, D.O. Dr. Lynch began his career at Washington and Jefferson University attaining a Bachelor of Arts degree in 1962. From there he attained a Doctor of Osteopathic Medicine degree at Philadelphia College of Osteopathic Medicine in 1966. He is a diplomat of the National Board of Osteopathic Examiners, American Board of Radiology, American Osteopathic Board of Radiology and has been re-certificated in each. He currently holds active medical licensure in 11 states. He has an outstanding military career ultimately attaining the rank of Brigadier General in the United States Army. During his military career he did his residency at Brooke Army Medical Center and was attached to the 82nd Airborne infantry, Fort Bragg and Airborne school at Fort Benning. He also attended the US Army War College, Command and General Staff College among others. He has served as commanding General of the 2nd Medical Brigade San Pablo, CA and 332nd Medical Brigade Nashville, Tenn. He also served on the Surgeon General’s Advisory Committee and Senior Army Reserve Commanders Association. While in the military he was awarded among other awards the Distinguished Service Award, Legion of Merit, Meritorious Service Medalx6 (Sliver Oak Leaf Cluster), Army Commendation Medalx2, Army Achievement Medal, Order of Military Medical Merit. He served as Commander of Medex in Japan, Commander of Army Reserve Medical Readiness in San Salvador, and has served on many humanitarian medical assistance missions to Indonesia, Sri Lanka, India, Nepal, Bangladesh and Honduras among others. He was elevated to Major General National Guard August 2001. As a civilian his deeds are no less dramatic. He has served in many hospitals including Eisenhower Medical Center where he served on the Executive, Cancer, Critical Care Cardiac Catherization, Cancer and Utilization committees. He has served at John F. Kennedy Memorial Hospital as Chief of Radiology and at Brooke Army Medical Center as Chief Mammography Section. He has also served as Director of Medical Imaging at the Desert Breast Institute in Rancho Mirage, CA and is co-founder of the Infrared Institute of the Desert. He has also served as a member of Tenet Health Care Task Force Interventional Radiology. He has numerous publications ranging from bioterrorism to Percutaneous Transluminal Angioplasty. He has devoted much of his time to POWs and combat stress diagnosis and treatment. Please review his entire CV as this space does not allow for all his achievements. He will serve as director of clinical imaging for Visionary Breast Centers. PERSONAL INFORMATION RICHARD D. LYNCH, D.O. 1406
Karl
1966
3346 Sable Creek
Home 210
San Antonio, Texas 78259 e-mail rdlynch916@aol.com
Cell Fax
Married: Mary J. Lynch
497 -
210 347-0020 210 497-5513 2 sons: Adam and
EDUCATION Doctor of Osteopathic Medicine 36
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Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania Bachelor of Arts Pre Medicine Washington and Jefferson University, Washington, Pennsylvania
2006
POSITIONS Multiple positions
November
Texas, Florida, California, New Jersey, Pennsylvania Locum Tenens
November 2006
December 2003
present
2002
2001
to present
INFRARED INSTITUTE OF THE DESERT LLC 35-280 Bob Hope Drive Suite #103 Rancho Mirage, California 92270 Co Founder
to present
DESERT BREAST AND OSTEOPOROSIS INSTITUTE 35-280 Bob Hope Drive Suite #103 Rancho Mirage, California 92270 Director Medical Imaging
BROOKE ARMY MEDICAL CENTER Mammography Radiology Department 3851 Roger Brooke Drive Fort Sam Houston, Texas 78234 Chief Mammography Section October 2002
1962
to present
May 2003 to October 2006
RICHARD D. LYNCH, D.O., P.A. A Texas Professional Association
to
President BROOKE ARMY MEDICAL CENTER Radiology Department Faculty 3851 Roger Brooke Drive Fort Sam Houston, Texas 78234 Staff Radiologist POSITIONS Continued
September to October 2006
JOHN F KENNEDY MEMORIAL HOSPITAL Radiology Department 47-111 Monroe Street Indio, California 92202 Chief, Department of Radiology
January to September 2002
37
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1996
JOHN F KENNEDY MEMORIAL HOSPITAL Radiology Department 47-111 Monroe Street Indio, California 92202 Chief, Interventional Radiology
to September 2002
RICHARD D. LYNCH, D.O. A MEDICAL CORPORATION 1996 Palm Desert, California President 1978
Present
1998
to September 2002
WESTERN UNIVERSITY OF HEALTH SCIENCE 309 Pomona Mall East Instructor, Department of Radiology
to September 2002
TOURO UNIVERSITY 1998 College of Osteopathic Medicine
to
Vallejo, California Instructor, Department of Radiology HEART INSTITUTE OF THE DESERT AND HEART HOSPITAL 39-600 Bob Hope Drive Rancho Mirage, California 92270 Staff Radiologist
to December 2000
EISENHOWER MEDICAL CENTER 1978 39-000 Bob Hope Drive Rancho Mirage, California 92270 Chief, Angiography, Neuroradiology, Interventional Radiology
to 1996
CERTIFICATION Diplomate, National Board of Osteopathic Examiners #411
1967
American Board of Radiology
June 1977
Diplomate American Osteopathic Board of Radiology
January 1978
CERTIFICATION Continued Fellow American College of Osteopathic Radiology (FAOCR)
December 1988
Recertification Diagnostic Radiology, American Osteopathic 38
May 1992
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Board of Radiology (10 years time limited) Certificate of Added Qualification (CAQ) American Osteopathic Board of Radiology – Angiography and Interventional Radiology Recertification Diagnostic Radiology, American Osteopathic Board of Radiology (10 years time limited)
May 1993
October 2001 Expires 2011
LICENSURE California Pennsylvania Texas New Jersey Florida NPI # 1962496414
STATUS 20A4096 OS 002336 EO 537 21758 0004068
Active Active
Active Active Active
RADIOLOGY QUALIFICATIONS General Diagnostic Radiology to include mammography/Breast Ultrasound and Percutaneous Breast Needle Localization/ Percutaneous Stereotactic Breast Biopsy, Ductograms, Percutaneous Ultrasound Guided Breast Biopsy, Percutaneous Metallic Clip Insertion, MRI Breast and MRI Guided Biopsies (Breast), Ultrasound Guided Cyst Aspirations, Specimen Radiography Mammography-Computer Aided Detection (CAD) Angiography, all phases to include Interventional Radiology and Percutaneous Transluminal Angioplasty and Stent Placement. Special procedures, major and minor Percutaneous Vertebroplasty Ultrasound with U/S Guided Biopsy Nuclear Medicine to include Cardiac Computerized Axial Tomography with CT Guided Biopsy, CTAngiography Magnetic Resonance Imaging/MRI Angiography RADIOLOGY QUALIFICATIONS Continued PET/CT Fusion Cerebral Revascularization Trials-
Medical Legal Consultant Plaintiff and Defense (14 years experience) Depositions and Hospital Consultant Medicolegal Issues TRAINING 39
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Internship – Rotating, Philadelphia College of Osteopathic Medicine
1966 to 1967
General Practitioner, Philadelphia, Pennsylvania July 1967 to October 1967 82nd Airborne Infantry, Fort Bragg North Carolina
October 1967 to October 1968
General Medical Officer, US Army (Airborne Infantry)
October 1968 to 1970
Commander, US Army Health Clinic, Karlsruhe, Germany
1970 to 1972
Residency - Brooke Army Medical Center, San Antonio, Texas 1972 to 1975 Fellowship (Angiography and Special Procedures) Walter Reed 1975 to 1976 Army Medical Center, Washington, DC Deployment Medicine Training (DEPMEDS) Fort Sam Houston Texas – Health Services Command Advanced Standing American College of Physician Executives Certified Level One in Infrared Technology - Awarded By FLIR
April 1989 1998 May 2007
MILITARY EDUCATION Basic Officer Course, AMEDD Basic Officer Advanced Course, AMEDD Command and General Staff College US Army War College Defense Equal Opportunity Military Institute (1998) Army Management School Force Integration Course Airborne School – Fort Benning, Georgia MILITARY EXPERIENCE Status 1978
Position/Rank
Duration
Active Duty, USAR
LTC, MC
Reserves, USAR
Brigadier General, MC
176th Medical Group/ Commander Brigade
August 1967 to 1978 to June 2001 1989 to 1995
40
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Los Alamitos, California 2nd Medical Brigade (63rd RSC) San Pablo, California
Commanding General
1995 to 1998
332nd Medical Brigade Commanding General June 1998 to June 2001 (81ST RSC) Nashville, Tennessee Senior Army Reserve Commanders Association (SARCA) Member, Association of Military Surgeons of the US Member , Army Reserve Forces Policy Comm. US Army Retired, USAR
Brigadier General
1989-Present 1993 to 2002 1996 to 1999 31 May 2001
RELEVANT MILITARY EXPERIENCE United States Army Reserve Retired Brigadier General
August 1967 to May 2001 31 May, 2001
Major General Major General National Guard South Carolina
promoted 1 August 2001 August 2001 to January 2002
Brigadier General Commanding General of the 2nd Medical Brigade in San Pablo, California US Army - Brigadier General Executive Training Surgeon General’s Advisory Committee for Reserve Medical Affairs
promoted
14 March 1996
October 1995 1993 to June 2001
Senior Army Reserve Commanders Association (SARCA) Brigadier General Richard D. Lynch Life member #190 RELEVANT MILITARY EXPERIENCE Continued United States Army Member, Army Reserve Forces Policy Committee
1996 to 1999
United States Army War College
1995 to 1997
MILITARY AWARDS Distinguished Service Award 41
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Legion of Merit Meritorious Service Medal x 6 (Silver Oak Leaf Cluster) Army Commendation Medal x 2 Army Achievement Medal National Defense Ribbon AMSUS Ribbon Parachutist Badge Expert Field Medical Badge Order of Military Medical Merit MILITARY OVERSEAS EXPERIENCES 2000
Medical Commander for Medex
August
USA Sagami Army Depot, Japan (21 Days) Medical Commander for XXXVII Yama Sakura Joint Military Exercise (Japan and United States) Itami, Japan (14 days) Medical Commander, U.S. Army Reserve Medical Readiness and Training Evaluation San Salvador, El Salvador 18th MedCom (Korea) Medical Planning Conference Seoul, Korea (1 week)
January 2000
February-August 1999
February 1997
MILITARY OVERSEAS EXPERIENCES Continued USARPAC – Delegate to Singapore Armed Forces Medical Subject Matter Experts (1 week)
January 1996
LECTURER –Combat Stress, Asia Pacific Military Medical Seminar – New Delhi, India (1 week)
January 1995
Humanitarian Medical Assistance Mission (U.S. Embassy) Indonesia (7 days) Humanitarian Medical Assistance to Sri Lanka 42
September 1994 August 1994
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US State Department (14 days) COMMANDER/LECTURER U.S. Army Humanitarian Civil Action Mission to India and Nepal (21 days)
August 1992
LECTURER – U.S Army Medical Mission to Bangladesh, Chief of Medical Mission (21 days)
August 1991
COMMANDER – DEPMEDS Hospital, Camp Dacotah, Honduras (7 days)
February 1989
ADDITIONAL AFFILIATIONS
Eisenhower Medical Center Committees Executive Committee Critical Care Committee Cardiac Catheterization Committee Education Committee Cancer Committee Practitioner Aid Committee Utilization Review Committee
1983, 1988
1984 1985-1991 1985 1985-1989 1987-1996 1993-1994
John F. Kennedy Memorial Hospital Committees Cardiovascular/Radiology January 2000-September 2002 Laboratory Committee Surgical Quality Assurance July 1998-September 2002 Brooke Army Medical Center, Fort Sam Houston, Texas Voting Member Breast Cancer May 2003-October 2006 Tumor Board
ADDITIONAL SELECTED PROFESSIONAL EXPERIENCE American Osteopathic College of Radiology Radiology Program Inspector Interventional Radiology Fellowship Program Inspector Tulsa Regional Medical Center Tulsa, Oklahoma
May 25, 2005
American Osteopathic College of Radiology, Dayton, Ohio March 10, 2003 Radiology Program Inspector Grandview Kettering Medical Center Tenet Health Care Systems Meetings, Member, Task Force Interventional Radiology American Osteopathic Board of Radiology 43
1998-September 2002 1993-May 2002
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Chairman April 2001-May 2002 Examiner Resident GI Radiology; CAQ-Interventional Radiology American Osteopathic College of Radiology Educational Foundation Member
1991-2001
American Osteopathic College of Radiology Chairman – Nominating Committee Past President President President Elect Secretary Board Member –AOCR
1993 1992-1993 1991-1992 1990-1991 1988-1990 1982-1993
HONORS
Certificate of Meritorious Service (Military Service to the nation) American Osteopathic College of Radiology September26, 2007 AOCR Annual Meeting – Boca Raton, Florida
Distinguished Service Award, United States Army
Distinguished Service Award, American College Of Osteopathic Radiology
Businessman of the Year, presented by the National Republican Congressional Committee’s Physician Advisory Board
October 2002 September 2002 2001
HONORS Continued
AOCR Trenery Lecturer Effective Utilization of Interventional Radiology – Educating the Patient, Medical Workers and Management
Award for Outstanding Service John F. Kennedy Memorial Hospital
1998
1996-2002
Aesculapius Award, awarded at General Staff Meeting for November 1996 service, dedication, and valuable contributions to Eisenhower Medical Hospital and its medical staff Fellowship in AOCR awarded by American Osteopathic College of Radiology
Mary K. Linback Scholarship Philadelphia College of Osteopathic Medicine
PUBLICATIONS 44
1988 1963-1964
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AUTHOR
The Bretz Stevenson Patch An Autologous Abdominal Fat Pad Transfer to Surmount the 7mm Skin Spacing Barrier in Using a Partial Breast Irradiation Device (APBI) Philip Bretz, M.D., John Stevenson, M.D. Richard Lynch, D.O., Philip Dreisbach, M.D. Luke Dreisbach, M.D. Presented Las Vegas Cancer Symposium
April 2006
AUTHOR: “Percutaneous Transluminal Angioplasty (PTA) and The Community Hospital Experience with 126 Cases” Journal of American Osteopathic Association November 1981 AUTHOR: “Inferior Vena Cava Duplication: Demonstration By Computed Tomography”, Radiology 130: 707-709, AUTHOR: “RPC from AFIP” Radiology, Volume 134, No. 2, 372-376 AUTHOR: “Cerebral Granulomatous Angiitis”, AJR, Vol. 129, No. 3, 463-467
March 1979 February 1978
September 1977
PUBLICATIONS Continued AUTHOR:
“The Celiac Axis Compression Syndrome” – Review of the literature and case report Journal of American Osteopathic Association 76(3): 189/77
November 1976
AUTHOR: “The External Carotid Artery – An Anomaly” Canadian Journal of Radiology
September 1975
CONTRIBUTOR
September 2001
“Bioterrorism” Desert Sun Newspaper
CONTRIBUTOR “Arterial Infections Due to LISTERIA MONOCYTOGENES: Report of Four Cases and Review Of World Literature” Clinical Infectious Diseases Volume 14-#1 23-8 January 1992 CONTRIBUTOR Montreal
Nocardia Asteroids Infections in Patients with Acquired Immune Deficiency Syndrome (AIDS) V International Conference on AIDS, June 4-9, 1989 45
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1989
CONTRIBUTOR
“Aids in Chest Disease”, ATM ORG. 172
VEB J.A. Barth, Leipzig CONTRIBUTOR “Dural Arteriovenous Malformation and Angina Pectoris: A Management Dilemma”, Letter to the Editor, Journal of Thoracic and Cardiovascular Surgery, Volume 95, No. 5, 941 May 1988 CONTRIBUTOR
1983
“Percutaneous Transthoracic Lung Biopsy “ Aspiration Biopsy in a Community Hospital By David Kaminsky, M.D.
VIDEO PRODUCER AND “Combat Stress Conference” DIRECTOR Richard Halmy Communications Conference at Camp Pendleton
2007
TV APPEARANCE “Bioterrorism and Anthrax in US Today
October 2001
ADDITIONAL POSITIONS Assistant Chief Department of Radiology Letterman Army 1976-1978 Letterman Medical Center, San Francisco, California
1978
Chief
Diagnostic Radiology, Letterman Army Medical Center, San Francisco, California
Chief
Angiography Special Procedures
1977-1978 1976-
Letterman Medical Center, San Francisco, California Vice President Palm Desert Radiology Medical Group, Inc.
1978-1993
Board of Directors
American Osteopathic College of Radiology
1982-1993
Chairman
Fellowship Awards Committee – American Osteopathic College of Radiology
1984-1988
Member
AOA/AOCR Inspection Team for Radiology Programs
Member
Educational & Evaluation Training Committee
2003
46
1984-Present 1985-1992 2001-
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1987
Member
1998
1990
Editorial Committee for Radiology
1982-
Residency Paper/Exhibit Review
1991-
Chairman
Revisions Committee, AOCR
1988-1989
Chairman
Research Committee, AOCR
1982-1988
Secretary
AOCR
1988-
President Elect AOCR (October 1990-September 1991) Member
Educational Foundation, Inc. (President)
President
AOCR (September 1991-November 1992
Past President AOCR (November 1992-September 19913 1995
1990-1991 1991 1991-1992 1992-1993
ACR Representative from AOCR
1992-
Chairman
Nominating Committee AOCR
1993
Chief
Interventional Billing, Palm Desert Radiology Medical Group
1983-1996
Member
Surgeon General’s Advisory Committee for Reserve Medical Affairs
1993-2001
Member
AOBR (American Osteopathic Board of Radiology) 1993-2002
ADDITIONAL POSITIONS Continued 1997
President
United States Army War College
1995-
Carlisle Barracks, Pennsylvania Member
Task Force Interventional Radiology Tenet Health Care System Meetings
1998-2002
Member
AOBR(American Osteopathic Board of Radiology) 1993-2002
Vice Chairman AOBR(American Osteopathic Board of Radiology) 2000-2001 Chairman
AOBR (American Osteopathic Board of Radiology) 2001-2002 47
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AMERICAN OSTEOPATHIC BOARD OF RADIOLOGY Oral Examiner AOBR Chicago, Illinois
April 2002
Oral Examiner AOBR Chicago, Illinois
October 2001
Oral Examiner AOBR Chicago, Illinois
April 2000
Oral Examiner Radiology and CAQ in Interventional Radiology
April 1999
Oral Examiner GI and Interventional Radiology
April 1998
Oral Examiner GI and Interventional Radiology Hilton Head, South Carolina
March 1996
Oral Examiner GI and Interventional Radiology Hilton Head, South Carolina
March 1996
PROGRAM CHAIRMAN/LECTURER LECTURER
Infrared Breast Imaging to be presented October 18, 2007 Inframation Conference FLIR Las Vegas, Nevada
LECTURER Breast Cancer Awareness February 2007 Citrus View Memorial Hospital February 24, 2007 Inverness Florida PROGRAM CHAIRMAN/LECTURER Continued LECTURER 1st-15th annual Tri Service Combat Stress Conference Camp Pendleton, California April 29-30, 2006, May, 2007 LECTURER
SAUSHEC LECTURER LECTURER
1993-present
Mammography Module Residency Program 2 weeks each Brooke Army Medical Center January 2003-2006 San Antonio, Texas Mock Board Examiner for Radiology, March 2004, April 2005 San Antonio, Texas April, 2006 VTC Lecture Use of Infrared Technology In Breast Diagnosis Mammography
January 2006 June 2006
48
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LECTURER April 2006
Interventional Radiology Module
LECTURER
Genitourinary Lecture
November 2004
LECTURER
Interventional Radiology Case Conference
April 2004
LECTURER
Discography – Formal Lecture
April 2004
LECTURER
Facet Joint Infections – Formal Lecture
April 2004
LECTURER
Lung Biopsy Update
LECTURER
Portal Hypertension – GI Section (VTC)
LECTURER
Vascular Ultrasound (Carotids)
LECTURER
Percutaneous Vertebroplasty (VTC)
LECTURER Conference
Interventional Radiology Case
September 2003 August 2003-2006 March 2003 December 2002 September-December 2002
GUEST LECTURER
Recent Advances in Vascular Radiology John F. Kennedy Memorial Hospital Indio, California
October 2001
GUEST LECTURER
51ST TRENERY LECTURE American Osteopathic College of Radiology Annual Meeting, Tucson, Arizona
October 1998
PROGRAM CHAIRMAN/LECTURER Continued
1997
CONFERENCE COORDINATOR AND LECTURER
6TH NATIONAL Tri-Service Combat Stress Conference POW Museum Andersonville, Georgia
LECTURER
“Is the AMEDD Ready for Chemical and
September 1998
November
Biological Warfare?” American Military Surgeons of the United States Nashville, Tennessee LECTURER
Tri-Service Combat Stress Seminar 2nd Medical Brigade, USAR Center Del Mar, California
LECTURER Medical Aspects of Operations Than War @ Asia Pacific Military Medical Conference, Kuala Lumpur, Malaysia 49
May 1997
March 1997
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LECTURER
“Medical Readiness in the U.S. Army”, American Military College of Physicians And Surgeons, San Antonio, Texas
LECTURER
“All Aspects of Interventional Radiology”, John F. Kennedy Memorial Hospital Indio, California
LECTURER
Tri-Service Combat Stress Seminar 2nd Medical Brigade, USAR Center Del Mar, California
May 1996
LECTURER
CT/MRI, College of Osteopathic Medicine Of The Pacific
April 1992
LECTURER
MRI Update, American Osteopathic College Of Radiology, Vail, Colorado
January 1992
LECTURER
MRI/CT of GI Tract, College of Osteopathic
June 1990
LECTURER
November 1996
October 1996
“New Aspects of Modern Radiology”, College of Osteopathic Medicine of the Pacific Pomona, California
June 1989
TASKFORCE Implementation of 4-Year Diagnostic April 1988 CHAIRMAN Radiology Program, Board of Directors AOCR PROGRAM CHAIRMAN/LECTURER Continued LECTURER
LECTURER June 1987
Fine Needle Aspiration Chest/Abdomen/Bone Breast Localization Techniques, Tripler Army Medical Center, Honolulu, Hawaii
July 1987
“New Dimensions in Radiology”,
California Medical Records Association Annual State Convention, Rancho Mirage, California
LECTURER
Cine CT, A New Imaging Modality for Cardiology Heart Institute of the Desert, Rancho Mirage California
LECTURER
Cross Sectional Imaging CT/MRI, Cine CT, College of Osteopathic Medicine of the Pacific
LECTURER
Plain Film Chest Interpretation, Heart Institute Of the Desert, Rancho Mirage, California
March 1987
LECTURER
Collaboration of the Interventional Radiologist
February 1987
50
June 1987
May 1987
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And Pathologist, 2nd International FNA Conference, Eisenhower Medical Center Rancho Mirage, California LECTURER Interventional Radiology, AOCR Winter AND PANEL Meeting, Palm Springs, California
January 1987
LECTURER Cine CT September 1986 AOCR Annual Meeting, Orlando Florida GUEST LECTURER
Percutaneous Breast Localization – Percutaneous June 1986 Fine Needle Aspiration of Chest/Abdomen Seminar on Interventional Radiology Techniques, Fitzsimons Army Medical Center, Denver, Colorado
GUEST Cross Section Imaging Techniques, CT/MRI May 1986 LECTURER College of Osteopathic Medicine of Pacific Pomona, California LECTURER
Radiological and Pathological Correlation of Percutaneous Breast Localization, Grand Rounds Eisenhower Medical Center, Rancho Mirage, California
PROGRAM Mid-year Meeting, American Osteopathic College CHAIRMAN PROGRAM CHAIRMAN/LECTURER Continued
May 1986
May 1986
LECTURER
Respiratory Therapy, Chest Imaging, Bright Horizons, Eisenhower Medical Center, Rancho Mirage, California
LECTURER
Angiography in G.I. Bleeding, G.I. Department December 1985 Eisenhower Medical Center, Rancho Mirage, California
LECTURER
Fine Needle Aspiration Chest & Abdomen American Osteopathic Association, American Osteopathic College of Radiology San Diego, California
LECTURER
Lyceum of the Desert Students Rancho Mirage, California
LECTURER
Fine Needle Aspiration of Abdominal Lesions XVI Desert Medical Classic Palm Springs, California
LECTURER
Update on Gastroenterology, CT Scan and 51
April 1986
October 1985
March 1985 May 1983
April 1983
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Fine Needle Aspiration of Abdominal Lesions Eisenhower Medical Center Rancho Mirage, California LECTURER
International Symposium on Aspiration Biopsy Eisenhower Medical Center Rancho Mirage, California
GUEST LECTURER
Tripler Army Medical Center Honolulu, Hawaii
LECTURER
Angiography/CT Correlation American College Of Osteopathic Radiology Boston, Massachusetts
LECTURER
Percutaneous Transluminal Angioplasty, American Association of Medical Transcriptionists Eisenhower Medical Center Rancho Mirage, California
LECTURER
Percutaneous Transluminal Angioplasty, 53rd Annual Clinical Assembly ACOS
January 1983
June 1982 October 1981
May 1981
October 1980
PROGRAM CHAIRMAN/LECTURER Continued LECTURER
Angiography of Gastrointestinal Bleeding, 52nd Annual Clinical Assembly, American Osteopathic College of Radiology Las Vegas, Nevada
LECTURER
Myelography, CT (Cerebral)-Epidural Venography March 1979 Special Procedures Seminar, American College of Osteopathic Radiologists Hilton Head, South Carolina
PROGRAM DIRECTOR AND LECTURER
Annual Meeting of Osteopathic Radiology Postgraduate Course, University of California San Francisco, California
October 1979
February 1978
POST GRADUATE COURSES AND SEMINARS
2007
Musculoskeletal MRI (33 Credits)
February
Duke University Clyde Helms, M.D. Director Annual Combat Stress Course West and Pacific States (12-16 Credits) From 1993 American Military Surgeons of the United States (AMSUS) to Present San Diego, California 52
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Annual Meeting American Osteopathic College of Radiology Las Vegas (33 Credits)
October 2006
Breast MRI (17 CEUs) Stanford University, Wynn Resort Las Vegas
October 2006
Mammography Update Santa Fe, New Mexico
June 2006
Mammography in The Next Millennium Santa Fe, New Mexico MRI Imaging of the Breast Advanced Diagnosis and Staging First Hill Imaging Seattle, Washington
June 2005 September 2004
Medico Legal Symposium (18 CME)
July 2004
Symposium on Radiology of the Pneumoconioses (16.5 Credit Hours) McLean, Virginia PET Imaging Conference (13.5 CME) Phoenix, Arizona
March 2004 February 2004
POST GRADUATE COURSES AND SEMINARS Continued SenoScan速 Digital Mammography Educational Training (8 CME) Denver, Colorado
November 2003
Teaching Course in Mammography (27 CME) Indian Wells, California Breast Imaging and Intervention from A to Z (19 Credit Hours) Las Vegas, Nevada
November 2003
October 2003
Oncologic Imaging for the Practicing Radiologist (15.5 Credit Hours)September 2003 MD Anderson Cancer Center University of Texas San Antonio, Texas PET/CT Imaging (32 Credit Hours) Mallinckrodt Institute of Radiology Division of Nuclear Medicine Washington University, St. Louis, Missouri
April 2003
Annual Meeting (33 Credit Hours) September 2002 American Osteopathic College of Radiology Vancouver, BC World Class Breast Imaging: You Can Provide It Loma Linda University of Medicine Continuing Medical Education Loma Linda, California Embolotherapy: Materials, Techniques and Clinical 53
August 2002
June 2002
Visionary Breast Centers Business Plan 06.22.14
Application Meeting (14.2 CMD hours) Society of Interventional Radiology American Osteopathic College of Radiology (27.5 hours) Las Vegas, Nevada
October 2001
Annual Review of Vascular and Interventional Radiology (20 hours) University of California San Diego San Diego, California
October 2001
Radiology in Italy (30 Hours) Case Western Reserve University Parma/Stresa, Italy
September 2001
Medical/Dental/Legal Update (20 Hours) May 2001 American Educational Institute Oranjestad, Aruba Cerebral Revascularization/MER (18 hours) University of South Florida Tampa Florida
March 2001
POST GRADUATE COURSES AND SEMINARS continued AOCR 2001 Mid-Year Conference (25 Hours) Puerto Vallarta, Mexico Radiology in Ireland (31 Hours) Case Western Reserve University Killarney and Dublin, Ireland
March 2001 September 2000
Percutaneous Vertebroplasty Seminar (5 Hours) University of Tennessee, Memphis, Tennessee
February 2000
CME John F. Kennedy Memorial Hospital (12 Hours) John F. Kennedy Memorial Hospital, Indio, California
January 2000
Domestic Violence Home Study (3 Hours) St. Louis University, St. Louis, Missouri
January 2000
HIV/AIDS Home Study 5 Hours January 2000 St. Louis University, St. Louis, Missouri Mammography Fellowship (20 Hours) University of California San Francisco San Francisco, California
December 1999
CME John F Kennedy Memorial Hospital (8 Hours) John F. Kennedy Memorial Hospital, Indio, California
December 1999
American Military College of Surgeons (40 Hours)
November 1999
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Anaheim, California CME John F Kennedy Memorial Hospital (8 Hours) John F. Kennedy Memorial Hospital, Indio, California
March 1999
CME John F Kennedy Memorial Hospital (17 Hours) John F. Kennedy Memorial Hospital, Indio, California
December 1998
Angiography and Interventional Radiology – Risk Management Harvard medical School, Boston, Massachusetts (3 days) Conference on Medical Management of Chemical and Biological Casualties (Certificate) (2 days) U.S. Army Chemical Defense Institute, Nashville, Tennessee 17th Annual Breast Imaging Conference Medical College of Wisconsin
October 1998 April 1998
September 1997
National Conference AMOPS (1 Week)
April 1997
POST GRADUATE COURSES AND SEMINARS Continued Diagnostic Imaging (1 Week) AOCR San Diego, California
November 1996
Clinical Practice – Mammography (1 Week) University of California San Francisco, San Francisco, California
November 1996
Ultrasound – OB/GYN and Abdominal (1 Week) Dallas, Texas
November 1996
Tri-Service Combat Stress Conference (2 Days) 176th Medical Brigade, Camp Pendleton, California
May 1995
Society of Cardiovascular and Interventional Radiology (31 Credits) Fort Lauderdale, Florida
March 1995
Annual Meeting, AOCR (31 Credits) Chicago, Illinois
October 1994
Health Care, Finance, and Medical Informatics (31 Credits) American College of Physician Executives Boston, Massachusetts Society of Cardiovascular and Interventional Radiology (28 Credits) San Diego, California Annual Meeting, AOCR (28.5 Hours )CME – Category 1 Chicago, Illinois Mid-Year Meetings, AOCR (1 Week) Kiawah, South Carolina
July 1994 March 1994 October 1993 May 1993
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SCVIR, New Orleans, Louisiana (1 Week) Physicians in Management Seminar III (1 Week) American College of Physician Executives Dana Point, California Physicians in Management Seminar II (31 Credits) American College of Physician Executives San Diego, California Annual Meeting AOCR (15 Credits Mammography, 31 Credits total) San Diego, California Annual Meeting ACR (5 days) Phoenix, Arizona POST GRADUATE COURSES AND SEMINARS continued Physicians in Management Seminar I (1 Week) Philadelphia, Pennsylvania Radiology Review Course May 1992 University of Florida
March 1993 February 1993
November 1992
October 1992 September 1992
June 1992
(1 Week)
Imaging of Cancer AOCR Mid-Year Meetings (1 Week) Detroit, Michigan
May 1992
Advanced MRI Musculoskeletal System (1 Week) University of California San Francisco, San Francisco, California
May 1992
Ultrasound Fellowship (1 week) May 1992 Yale University Medical Center Proctor--Lynwood Hammers, D.O. Chairman Teaching Course in Mammography The School of Medicine, University of Missouri Reno, Nevada (TABAR) Diagnostic Imaging Updates American Osteopathic College of Radiology Scottsdale, Arizona
January 1992
September 1991
Vascular and Interventional Radiology Fellowship (1 Week) Miami Vascular Institute Director-- B. Katzen, M.D.
May 1991
MRI Fellowship – MRI Brain/Angiography (1 Week) University of California San Francisco, San Francisco, California
May 1991
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Visionary Breast Centers Business Plan 06.22.14
Society of Cardiovascular and Interventional Radiology (1 Week) San Francisco, California Interventional Radiology Fellowship (1 Week) Proctor – Ernest Ring, M.D. Society of Cardiovascular and Interventional Radiology Annual Meeting Miami, Florida Magnetic Resonance Update (4 days) University of Florida, Palm Beach, Florida
February 1991 November 1990 March 1990 February 1990
Annual Meeting AOCR (5 days) October 1989 Orlando, Florida POST GRADUATE COURSES AND SEMINARS continued Ultrasound Review (2 Days) September 1989 University of San Diego, Department of Radiology San Diego, California Annual Meeting, AOCR (5 Days) December 1988 Las Vegas, Nevada Angiography and Interventional Radiology 3 Days Harvard Medical School, Boston, Massachusetts
October 1988
Neuroradiology Review (2 Days) May 1988 Loyola School of Medicine, Chicago, Illinois Annual Meeting AOCR (5 days) October 1987 Tucson, Arizona Cine CT, CT/MRI, Visiting Fellowship (5 days) University of California Medical Center, San Francisco, California Society of Cardiovascular and Interventional Radiology (4 Days) San Diego, California Certified Advanced Trauma Life Support (ATLS) (2 Days) U.S. Army Health Services Command, San Antonio, Texas MRI Fellowship (1 Week) October 1986 57
June 1987 March 1987 February 1987
Visionary Breast Centers Business Plan 06.22.14
University of Pennsylvania, Philadelphia, Pennsylvania 11th Annual Course on Diagnostic Angiography and Interventional Radiology Ft. Lauderdale, Florida
February 1986
Magnetic Resonance Imaging Visiting Fellowship University of California San Francisco, San Francisco, California
January 1986
MRI Fellowship September 1985 Walter Reed Army Medical Center, Washington DC Oncology Fellowship and Interventional Radiology (2 Weeks) M.D. Anderson Hospital, Houston, Texas
September 1985
Staff Radiologist (1 Week) June 1985 Elmendorf AFB Hospital, Anchorage, Alaska POST GRADUATE COURSES AND SEMINARS continued 10th Annual Course on Diagnostic Angiography and Interventional Radiology Orlando, Florida American Osteopathic Association, AOCR Meeting New Orleans, Louisiana American Institute of Ultrasound in Medicine Kansas City, Missouri
February 1985
October 1984 September 1984
Visiting Fellowship Program, Mammography/Ultrasound University of California San Francisco, San Francisco, California
July 1984
Cardiac Lecture Series “50,000 Open Heart Operations�, The Texas Heart Institute, Denton A. Cooley, M.D. Eisenhower Medical Center, Rancho Mirage, California
April 1984
Mid-year Conference, Pediatric Radiology (2 Days) AOCR, Chicago, Illinois
May 1984
Neuroradiology Review Course (2 days) Loyola University, Stritch School of Medicine Chicago, Illinois
May 1984
Underwater Medicine (1 Week) Temple University School of Medicine Philadelphia, Pennsylvania
January 1984
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90th Annual Association of Military Surgeons of the United States Annual Meeting, San Antonio, Texas
November 1983
56th Annual Training Assembly, ACOS/AOCR Toronto, Canada
October 1983
ACR – Abdominal Ultrasound Course – OB/GYN (2 Weeks) Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
October 1980
Cerebrovascular Diagnosis Seminar Desert Hospital, Palm Springs, California Computerized Tomography, VII Annual International Meeting Las Vegas, Nevada Angiography and Vascular Diagnosis University of California San Diego, San Diego, California
DAVID W. MANTIK, M.D., Ph. D. Department of Radiation Medicine Loma Linda University Medical Center 11234 Anderson St., PO Box 2000 Loma Linda, CA 92354 Phone: 909-558-4243 FAX: 909-558-4083 CURRICULUM VITAE PERSONAL: Name: David Wayne Mantik Date of Birth: October 13, 1940 Place of Birth: Milan, Wisconsin Family: Wife: Patricia L. James, M.D. Children: Christopher (1985) Meredith (1987) EDUCATION/ACHIEVEMENTS: High School : Merrill Senior High School 1954-1958 Merril, Wisconsin University: 1958-1962
BS, Physics
University of Wisconsin
Graduate: 1962-1963
University of Illinois MS, Physics 59
May 1980 April 1980 January 1980
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1963-1967 PhD, Physics
University of Wisconsin
Medical School: 1972-1976 MD
University of Michigan
Internship: 1976-1977
LAC/USC Medical Center Los Angeles, California
Residency: 1977-1980
Radiation Oncology LAC/USC Medical Center Los Angeles, California
Fellowships: 1962-1963 Graduate Fellowship
Physics, University of Illinois National Science Foundation
1967-1969 Biophysics, Stanford University National Institutes of Health 1980-1983 American Cancer Society Junior Faculty Clinical Fellowship #568 Loma Linda University Medical School Loma Linda, California POSITIONS HELD Physics: 1969-1972
Assistant Professor of Physics University of Michigan-Flint
Radiation Oncology: Assistant Professor of Radiation Oncology 1980-1982 Director of Resident Training Program Loma Linda University Medical School 1983-present Staff Radiation Oncologist Eisenhower Memorial Hospital 1990-1997 Director of Radiation Oncology Eisenhower Memorial Hospital 1997-present Associate Professor of Radiation Oncology Loma Linda University Medical School (specializing in head & neck cancer) COMMITTEES: Cancer Committee: 1990-1997
Eisenhower Memorial Hospital
Chairman, Cancer Committee: Eisenhower Memorial Hospital 1990-1992 60
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LICENSURE and CERTIFICATION: American Board of Radiology Therapeutic Radiology June 1980 National Board of Medical Examiners: 1977
Certificate Number 167572
California Medical License 1997
Certificate Number G-034416
Oregon Medical License 1990
Certificate Number MD16697
Washington Medical License 1991
Certificate Number 025209 MD 00029255
Drug Enforcement Administration 1977
Certificate Number AM-7613690
Federal Tax ID
33-0016077
UPIN
A45919
Individual Medicare Number
00G344160 (billing under group #ZZZ13885Z)
OTHER PROFESSIONAL ACTIVITIES University of Wisconsin
Phi Beta Kappa, 1960 Phi Kappa Phi, 1960
LAC/USC Medical Center
Clinical Cancer Associate, 1979-1980
Who’s Who in California
1980
MEMEBERSHIPS American Radium Society American Society of Clinical Oncologists American Society of Therapeutic Radiologists and Oncologists California Medical Association Los Angeles Radiologic Society Riverside County Medical Society 61
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RESEARCH GRANTS University of Michigan Rackham Faculty Research Grant, 1970-1972 HOBBIES Classical music, opera, hiking, basketball, traveling, omnivorous reading ACADEMIC APPOINTMENTS Assistant Professor of Physics 1966-1972
University of Michigan-Flint
Clinical Instructor in Radiology 1979-1980 Los Angeles, California
LAC/USC Medical Center
Asst & Assoc Professor of Radiation Sciences 1980-present
School of Medicine Loma Linda University
RESEARCH ACTIVITIES 1. Senior Thesis, 1962: “Sodium Vapor Pressure, 100-150 degrees C.” 2. A Computer Model of Amorphous Structure, 1964, 3M Company. 3. PhD Dissertation, 1967: “X-ray Scattering from Amorphous Proteins and Solutions; Calculations of Scattering from Various Models.” 4. Post-Doctoral Research, 1967-1969: “ESR and Phosphorescence of Several Amino Acids and Proteins, NMR and Differential Optical Absorption Of a Dipeptide.” 5. DW Mantik, “Electron Spin Resonance, Phosphorescence, Nuclear Magnetic Resonance, and Differential Optical Absorption Observations on Several Amino Acids and Proteins,” Biophysical Journal Society, Abstracts 9: A-160 (1969). 6. University of Michigan Physics Faculty, 1970-1971: “Energy Transfer in a Cyclic Dipeptide.” 7. DW Mantik, “ A Flexible Grading System for Introductory Physics,” Physics Teacher, 9: 340 (1971). 8. DW Mantik, “A Simple Method for Measuring the Earth’s Magnetic Field,” American Journal of Physics, 39: 965 (1971). 9. Medical Student Research, 1973: “Oxygen Pulse-Induced pH Changes in Anaerobic Suspensions of Euthyroid vs. Hypothyroid Rats.”
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10. DW Mantik, HW Puffer, MA Astrahan, AMN Syed, et al., “Radiofrequency Induced Hyperthermia in Afterloading Iridium-192 Implantation,” presented at the 20th ASTR Annual Meeting, 1978, Int J Radiation Oncology Biol Phys 4: 225, Supplement 2 (1978). 11. DS Gridley, RL Nutter, DW Mantik, JM Slater, “Hyperthermia and Radiation in Vivo: Effect of 2-deoxy-D-glucose,” Int J Radiation Oncology Biol Phys 11: 567 (1985). 12. DS Gridley, RL Nutter, DW Mantik, JM Slater, “Mouse Neoplasia and Immunity: Effects of Radiation, Hyperthermia, 2-deoxy-D-glucose, and Corynebacterium parvum,” Oncology 42: 391-398 (1985). BOOKS ASSASSINATION SCIENCE: Experts Speak Out on the Death of JFK Edited by James Fetzer, Catfeet/Open Court Press (1988) ISBN 0-8126-9365-5 ISBN 0-8126-9366-3 Contributed Chapters: --Cause for Doubt: the JFK Assassination [on the medical evidence] --The President John F. Kennedy Skull X-rays: Regarding the Magical Appearance of the Largest “Metal” Fragment. --Special Effects in the Zapruder Film: How the Film of the Century was Edited. MURDER IN DEALEY PLAZA: What We Know Now That We Didn’t Know Then about the Death of JFK, Edited by James Fetzer, Catfeet/Open Court Press (2000) ISBN 0-8126-9422-8 Contributed Chapters: --Paradoxes of the JFK Assassination: The Medical Evidence Decoded --Paradoxes of the JFK Assassination: The Zapruder Film Controversy --Paradoxes of the JFK Assassination: The Silence of the Historians --Conversation with John Ebersole, MD (2 December 1992) --Deposition of J Thornton Boswell, MD (26 February 1996)
CURRICULUM VITAE 63
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Name: BORKO B. DJORDJEVIC, M.D., Ph.D., F.I.C.S. Address: 123 Kavenish Drive Rancho Mirage, California 92270 Tel: 760-325-7777 e-mail: borkomd@aol.com Website: www.djordjevicmd.org Date of Birth: March 3, 1942 Place of Birth: Pirot, Serbia Citizenship: USA – Serbia EDUCATION Preprofessional: Fifth Belgrade High School Degree: Bachelor of Science 1957 – 1961 Professional: University of Belgrade School of Medicine, Belgrade, Yugoslavia Degree: Doctor of Medicine 1961 - 1968 Internship: Institute of the Socialist Republic of Serbia for the Public Health, Belgrade, Yugoslavia Type: Rotating 1968 – 1969 Yugoslav National Army Medical Officer 1969 – 1970 St. Barnabas Medical Center Livingston, New Jersey, USA Type: Rotating 1971 - 1972 Residency: Speciality: General Surgery Mountainside Hospital Montclair, New Jersey, USA 1972-1974 Speciality: General Surgery The Graduate Hospital University of Pennsylvania Philadelphia, Pennsylvania, USA 1974 - 1975 Speciality: Plastic and Reconstructive Surgery, Surgery of the Hand and Genitalia, Cosmetic Surgery Riverside Methodist Hospital Affiliate of Ohio State University Columbus, Ohio, USA 1975 - 1977 Chief Resident in Plastic and Reconstructive Surgery, Surgery of the Hand and Genitalia, Cosmetic Surgery Riverside Methodist Hospital Affiliate of Ohio State University Columbus, Ohio, USA 1976 - 1977 Continuing Medical Education: Medical Review Course St. Barnabas Medical Center 64
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1976
Livingstone, New Jersey, USA 1970 – 1971 Annual Meeting Ohio Valley of Plastic and Reconstructive Surgery Society Maceno Island, Michigan, USA 1976 ASPRS/PSEF/ASMS Annual Scientific Meeting, Boston, Messachusetts, USA
Backer’s Cosmetic Surgery Meeting Mount Sinai Miami Beach, Florida, USA 1976 Backer’s Cosmetic Surgery Meeting Mount Sinai Miami Beach, Florida, USA 1977 Chief Surgical Resident in Plastic and Reconstructive Surgery Conference Chicago, Illinois, USA (Presented paper: THERATOMA OF THE NECK) 1977 American Society of Aesthetic Surgery Annual Meeting, USA February, 1977 American Cleft Palate Education Foundation Annual Meeting, USA March, 1977 ASPRS Education Foundation Chief Residents’Annual Meeting March, 1977 Ohio Valley Society of Plastic and Reconstructive Surgeons, Ohio Walley Meeting, USA June, 1977 Eastern Virginia Medical Society Conference on Reconstructive Surgery, USA June, 1977 Northwestern University Plastic Surgery Department Post-Graduate Course in Plastic Surgery September, 1977 Indio Comunity Hospital (John F. Kennedy Memorial Hospital) Grand Rounds September, 1977 – June, 1978 Eisenhower Medical Center Rancho Mirage, California, USA Weekly Conferences Impotence: Perspectives or Evaluation and Management April, 1978 Desert Hospital, Palm Springs, California Cardiovascular Exam (CPR) May, 1978 Plastic Surgery Research Foundation Breast Reconstructions Following Mastectomy December, 1978 Review Course Plastic and Reconstructive Surgery Stanford Uniersity, Palo Alto, California, USA 1978 American Society of Aesthetic Surgery Problems in Aesthetic Surgery January, 1979 American Society of Plastic and Reconstructive Surgeons, Annual Meeting New Orleans, Louisiana, USA September, 1980 Review Course American Board of Plastic and Reconstructive Surgery Northwest University, Chicago, Illinois, USA (Written Exam) 1983 ASPRS/PSEF/ASMS Annual Scientific Meeting New Orleans, Lousiana, USA 1986 65
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Review Course American Board Plastic and Reconstructive Surgery Stanford University, Pelo Alto, California, USA (Oral exam) 1987 Review Course American Board Plastic and Reconstructive Surgery Stanford University, Palo Alto, California, USA 1988 ASPRS/PSEF/ASMS Annual Scientific Meeting Washington Convention Center Washington, D.C., USA 1992 International Symposium on Plastic Surgery Firence, Italy 1994 Doctor Thesis „Secondary Rhinoplasty“ University of Belgrade, School of Medicine Belgrade, Yugoslavia Degree: Doctor of Medical Sciences 1994 ASPRS/PSEF/ASMS Annual Scientific Meeting Dallas, Texas, USA 1996 Advances in Aesthetic Plastic Surgery The Cutting Edge Symposium Manhattan Eye, Ear and throat Hospital, New York 1996 Laser Workshop: treatment of Cutaneous Lessions Skin Laser Center, New Jersey, USA 1997 American Academy of Cosmetic Surgeons Annual Meeting Century City, California, USA 1999 16th Annual Plastic Surgery Day-Annual Meeting Cedars-Sinai Medical Center Los Angeles, California, USA 1999 California Academy of Cosmetic Surgery Annual Meeting and Education Program Annenberg Center-Eisenhower Medical Center Rancho Mirage, California, USA 1999 American Academy of Plastic Surgeons Annual Scientific Meeting Los Angeles, California, USA 2000 17th Annual Plastic Surgery Day – Annual Meeting Cedars-Sinai Medical Center Los Angeles, California, USA 2000 California Academy of Cosmetic Surgery Annual Meeting and Education Program Annenberg Center-Eisenhower Medical Center Rancho Mirage, California, USA 2000 ASPS/PSEF/ASMS Annual Scientific Meeting Los Angeles, California, USA 2000 PSEF – In Service Exam 2001 CME – Medical Ethics-4th Edition 2001 ASPS/ACCME In-Service Exam 2001 ASPS/PSEF/ASMS Courses 2001 19th Plastic Surgery Day Cedars-Sinai Medical Center 66
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2010
Los Angeles, California, USA 2002 ASPS/PSEF/ASMS Scientific Meeting 2002 University of Belgrade, Serbia Taught at the School of Medicine 2002 American Society of Plastic Surgeons PSEF In-Service Exam 2003 International College of Surgeons CA Division Surgical Update 2003 Medical Educational Resources Advances in Cosmetic Surgery 2003 18th Annual Symposium on the Latest Advances in Facial Plastic Surgery Newport Beach, California, USA 2004 19th Annual Symposium on the Latest Advances in Facial Plastic Surgery Newport Beach, California, USA 2005 Cosmetic Surgery Board Annual Board Meeting San Diego, California, USA 2005 The Foundation for Facial Plastic Surgery The 20th Annual Symposium on the Latest Advances in Facial Plastic Surgery New Port Beach, California, USA 2006 California Academy of Cosmetic Surgeons 8th Annual Educational Meeting Advances in Cosmetic Surgery Rancho Mirage, California, USA 2006 Plastic Surgery Educational Foundation New Horizons Comprehensive Facial Rejuvenation Indian Wells, California, USA 2007 Medscape Decreased Alertness in a 10-Month-Old Girl February 2010 Medscape A 40-Day-Old Boy With Facial Swelling February 2010 Medscape Aesthetic Medicine CME/CE Collection: Volume 6 February 2010 Medscape Facial Rejuvenation With AbobotulinumtoxinA of a 45-Year-Old Man February 2010 Medscape Problematic Melanocytic Lesions in Children February 2010 Medscape The Last Hours of Living: Practical Advice for Clinicians February 2010 Medscape A 50-Year-Old Man With Left Upper Quadrant Pain and Pyrexia February 2010 Medscape Factors Associated With Complications in Older Adults With Isolated Blunt Chest Trauma February 2010 Medscape Soft Dring Consumption Linked to Pancreatic Cancer February 2010 Medical Education Resources Plasma Safety: Perspectives on Emerging Pathogens and Practice Implications February Medscape New Developments in Aesthetic Therapy With Botulinum Neurotoxin A February 2010 67
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2010
PennState College of Medicine Resistance Wars III: On the Frontlines of Serious Infections February 2010 National Comprehensive Cancer Network NCCN-MedscapeCME Oncology: Non-Small Cell Lung Cancer Tumor Board February
Medscape A 47-Year-Old Man With Acute Epigastric Pain February 2010 Medscape Diabetes Slows Return of Continence After Leparoscopic Prostatectomy February 2010 Medscape Liver Metastases From Colorectal Cancer: Radioembolization With Systemic Therapy February 2010 Medscape Dermatomyositis: Current and Future Treatments February 2010 Medscape Commentary on a Patient Case: Controversies and Dilemmas in Ventral Hernia Repair – Selecting the Biologic Mesh February 2010 Medscape The Clinical Picture of Adult Male Hypogonadism: A Case-Based Approach March 2010 Medscape Management of Erectile Dysfunction Reviewed March 2010 Medscape Dying to be Thin March 2010 Medscape Pathophysiology, Diagnosis and Management of Postoperative Dumping Syndrome March 2010 Medscape Expert Highlights and Clinical Perspectives From San Antonio Breast Cancer Symposium (SABCS) 2009 March 2010 University of California, Irvine School of Medicine The Skin-Mind Connection: Treatment of Eczema and Other Common Skin Disorders – Beyond the Use of Pharmacologic Interventions March 2010 Medscape Topical Clindamycin Preparations in the Treatment of Acne Vulgaris March 2010 Medscape The Topical Treatment of Psoriasis, Vol.2 March 2010 Medscape Erectile Dysfunction Following Prostatectomy: Prevention and Treatment March 2010 Medscape Adverse Effects of Androgen Deprivation Therapy: Defining the Problem and Promoting Health Among Men With Prostate Cancer March 2010 Medscape Review of Evidence-Based Support for Pretreatment Imaging in Melanoma March 2010 Medscape Primary Care Management of Keloids nad Hypertrophic Scars Reviewed March 2010 Medscape The Case of the Peripatetic Pyhsician: A Strategy to Avoid Accountability March 2010 68
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2010
Medscape Facial Shaping With Fillers March 2010 Medscape Seizures in a 42-Year-Old Man in Methadone Treatment March 2010 Medscape Outcomes in Acute Postoperative Pain: Emerging Treatment Options March 2010 Medscape To Their Detriment, HPV-Positive Head and Neck Cancer Patients May Also Be Smokers March 2010 Medscape Improving Outcomes and Quality of Life in Patients With Head and Neck Cancer March
SciMed Clinical Implications of HPV Prevention: Evaluating the Impact and Preparing for the Future March 2010 Medscape Fluid Balance and Acute Kidney Injury March 2010 Medscape Upper Gastrointestinal Bleeding in a 47-Year-Old Man March 2010 Medscape Evaluation and Management of the High-Risk Patient With Atrial Fibrillation March 2010 Medscape Implementing Enhanced CDC Recommendations for HIV Testing and Linkage to Care: An Expert Interview With Veronica Miller, PhD March 2010 Medscape The Diagnosis and Clinical Management of HIV March 2010 Medscape Novel and Successful Approaches to HIV Screening March 2010 Medscape A Primer on HIV Testing and Initial Treatment March 2010 Medscape Considerations in the Role of Male Circumcision in the Prevention of HIV Transmission in the USA March 2010 Medscape Study Does Not Support HPV Vaccine in Older Women March 2010 Medscape HPV Vaccine Reduces Rates of Genital Diseases in Young Women March 2010 Medscape Meta-Analysis Provides Strong Support for Chemoradiotherapy in Cervical Cancer March 2010 Medscape MRI and PET Scans for Primary Staging and Detection of Cervical Cancer Recurrence March 2010 SciMed Tackling the Issues Surrounding HPV Prevention: What You Need to Know Now March 2010 Medscape Dyspnea After In Vitro Fertilization March 2010 69
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USF Health Explore, Expand&Enhance – Incorporating the Beauti“phi“cation Approach with Hyaluronic Acid Dermal Fillers to Enhance Facial Beauty March 2010 USF Health Explore, Expand & Enhance Refining Injection Rechniques with Hyaluronic Acid Dermal Fillers March 2010 Serbian Association for Anti-Aging Medicine (SAAAM) 2nd International Congress on Anti-Aging Medicine and Regenerative Biomedical Technologies Belgrade, Serbia May 2010 Croatian Society for Plastic, Reconstructive and Aesthetic Surgery VIII Croatian Congress of Plastic, Reconstructive and Aesthetic Surgery October 2010 Serbian Association for Anti-Aging Medicine (SAAAM) Advanced use of Botox the lecturer/educator for leading the workshop June 2011 Medscape In My Practice: Combination Therapy With Neurotoxins and Fillers September 2011 Annenberg Center for Health Sciences at Eisenhower Volume Restoration in Aesthetics: The Art of The Global Approach September 2011 Annenberg Center for Health Sciences at Eisenhower Perfecting the Use of Neurotoxins in Facial Aesthetics .... Decisions, Decisions September 2011 The Institute for Medical Quality – California Medical Association, IMQ PROFESSIONALISM PROGRAM Certificate of Attendance February,4-5, 2013 European Accreditation Council for Continuing Medical Education (EACCME) Body Contouring Workshop: Patient Safety in New Approaches for Body Contouring 24 – 25 Maj 2013 PRESENT MEDICAL AND SURGICAL APPOINTMENTS 1. Director and Chairman, Department of Plastic and Reconstructive Surgery, Mediterranean Surgery Center, Igalo, Montenegro Adress: Save Ilica 5, 85347 Igalo Tel: + (382) 31 332 770 Fax: + (382) 31 332 771 1995 – Present 2. Contributing Editor, Journal of Medical Research University of Belgrade, Serbia 1991 – 1993 3. Associate Professor, Plastic and Reconstructive Surgery University of Belgrade, School of Medicine, Belgrade, Serbia 1996 – Present 4. Associate Professor, Plastic and Reconstructive Surgery University of Niš, Serbia 1996 – Present 5. Member Investigator Western Institutional Review Board (WIRB) Study: Adjunct Study of Mentor H/S Silicone Gel-filled 1998 – 2007 Staff Privileges in Plastic and Reconstructive Surgery, Cosmetic, Maxillo-Facial and Hand Surgery in the following hospitals: 1. Mediterranean Surgery Center 70
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Save Ilica 5, Igalo, Montenegro 1989 – Present 2. Aurora Surgery Center 73-950 Alessandro Drive, Suite 1 Palm Desert, CA 92260 2004 – 2008 3. Doctors Surgery Center 10900 Warner Ave., Suite #101A Fountain Valley, CA 92708 2004 – 2006 4. Beverly Hills Surgical Institute: Upland Surgical Institute 930 W. Foothil Blvd., Suite B Upland, CA 91786 2005 – 2007 5. Rancho Specialty Hospital 10841 White Oak Rancho Cucamonga, CA 91730 2006 – 2007 6. Belgrade Medical Center (KBC) Milutina Milankovica 3 11070 Belgrade, Serbia 2009 – Present 7. Special Hospital „Sveti Vid“ Dobracina 27, 11000 Belgrade, Serbia 2010 – Present 8. Welness Center „Maestral“ Montenegro Przno, 85315 Sveti Stefan, Montenegro 2010 - Present RESEARCH GRANTS 1. Junior Research Fellow Grant, Physiology, University of Belgrade, Serbia 1963 – 1966 2. Practical Teacher Grant, Physiology Grant, Research in Electrophoresis of the Proteins, Belgrade, Serbia 1963 – 1965 3. Senior Member of Student Exchange Program Grant University of Belgrade, Serbia 1964 – 1966 4. Board Member of the Student Council Grant School of Medicine, University of Belgrade, Serbia 1994 - 1996 FORMER APPOINTMENTS 1. Medical Exam Commissioner of the State of California Board of Medical Quality Assurance, USA 1983 – 1987 2. Chairman of the Board and Chief Executive Officer Oil Securities, INC., (NASDAQ) Acquisition and management of numerous domestic oil and gas properties in North America with special emphasis on alternative energy sources. 1986 – 1989 3. Special Appointment by former President Jimmy Carter, to assist the Carter Center of Atlanta, Georgia, in their efforts to further peace in the Bosnian-Yugoslavian countries. Solely responsible for bringing President Carter personally to Bosnia in December 1994 to further the peace efforts. 1994 – 1996 FORMER HOSPITAL STAFF PRIVILEGES 1. Rehabilitation Assistant, Orthopedic Department Orange Memorial Hospital, New Jersey, USA 1970 – 1971 2. Member of Medical Staff in Plastic and Reconstructive Surgery Eisenhower Medical Center Rancho Mirage, California, USA (Status: Resigned) 1977 – 1988 71
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3. Member of Medical Staff in Plastic and Reconstructive Surgery John F. Kennedy Hospital Indio, California, USA (Status: Resigned) 1977 – 1988 4. Member of Medical Staff in Plastic and Reconstructive Surgery Desert Hospital Palm Springs, California, USA (Status: Resigned) 1978 – 1989 5. Member of Medical Staff in Plastic and Reconstructive Surgery Beverly Hills Medical Center Beverly Hills, California, USA (Status: Facility Closed) 1984 – 1989 6. Member of Medical Staff in Plastic and Reconstructive Surgery Westside Medical Hospital Los Angeles, California, USA (Status: Facility Closed) 1994 – 1996 7. Member of Medical Staff in Plastic and Reconstructive Surgery Santa Ynez Valley Hospital Solvang, California, USA 1994 – 1996 8. Member of Medical Staff Desert Surgery Center Palm Springs, California, USA (Status: Facility Closed) 1996 - 2004 LICENSURE 1. State of California – canceled May 13, 2010
1977 – 2008
CERTIFICATION 1. EFCMG 1971 2. FLEX 1975 3. American Board of Plastic and Reconstructive Surgery (Written) 1984 4. Advanced Trauma Life Support 1986 5. American Board of Cosmetic Surgery 1994 6. Doctor of Medical Sciences – Ph.D., University of Belgrade 1994 7. Associate Professor, University of Belgrade, School of Medicine 1996 8. Associate Professor, University of Niš, School of Medicine 1996 9. BCLS/CPR „C“ – Health Care Provider, Life Saver Systems 2005 ACADEMIC APPOINTMENTS 1. Instructor of Physiology University of Belgrade, Serbia 1963 – 1966 2. Deputy Governor American Biographical Institute Research Association North Carolina, USA 1996 – Present 3. Professor of Surgery University of Belgrade, Serbia 1996 – Present 4. Professor of Surgery University of Niš, Serbia 1996 – Present 5. Teaching Professor of Postoperative Care Queen Jelena nursing school Igalo, Montenegro 2008 - Present
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AWARDS AND CITATIONS 1. Distinguished Citizen of State of New Jersey, USA 2. Who is Who – California, USA, 1983 3. American Medical Association, Physician Recognition Award for 1985 4. Who is Who – California, USA, 1996 5. Man of the Year – American Biological Institute – 1996 6. California Medical Association – Certificate of Excellence 1996 - 1999 7. American Medical Association, Physician Recognition Award 1997 – 2000 8. 20th Century Award of Achievement 1997 9. Distinguished Leadership Award, International Directory 1997 10. American Medical Association, Physician Recognition Award 2000 – 2003 11. Humanitarian Award – Golden Palm Star – Palm Springs, California 2001 12. Man of the Year Award –Greater Palm Springs Celebrity Golf Classic 2001 13. Republican Senatorial Medal of Freedom 2002 14. Ellis Island Medal of Honor, 2010 MEMBERSHIP AND FELLOWSHIPS IN PROFESIONAL SOCIETIES 1. American Medical Association 2. The New York Academy of Medicine 3. Palm Springs Academy of Medicine 4. American Academy of Cosmetic Surgery 5. American Society of Lipo-Suction Surgery 6. American Society of Hair Restoration Surgery 7. International College of Surgeons
SOCIAL MEMBERSHIP 1. Republican Senatorial Inner Circle 2005 2. Senator’s Club, Washington, D.C., USA 3. Presidential Business Commission 2005 CURRENT MEETING INFORMATION Since 1978, I have lectured at many professional conferences. The following is a list of some recent topics: 1. Speaker Reconstruction of Big Skin Defects of the Face and Neck XII Congress E.A.C.M.S., Hague, Holland 1994 2. Speaker Secondary Rhinoplasty XII Congress E.A.C.M.S. Hague, Holland 1994 3. Speaker Bacteriological and Pathological Studies in Patients with Artificially Opened Macillary Sinus XII Congress E.A.C.M.S. Hague, Holland 1994 4. Serbian Association for Anti-Aging Medicine (SAAAM), Belgrade, Serbia – Lecture antiaging 2010 5. Serbian Association for Anti-Aging Medicine (SAAAM), Belgrade, 73
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Serbia – Lecture antiaging today2011 6. Serbian Association for Antiaging Medicine (SAAAM), Belgrade, Serbia – Lecture of advanced use of botox 7.
2011
European Accreditation Council for Continuing Medical Education (EACCME) – Lectures liposculpture of lower body 2013
PUBLICATIONS 1. Djordjevic, B., Visnjic M., Jeremic M., Burie N: „Local Skin Flaps in Reconstruction of Head Defects“, I. Mediterranean Congress of oral and Maxillofacial Surgery, Athens, 1991. 2. Djordjevic B., Visnjic M., Visnjic Z.: „Reconstruction of Defects of the Eyelids“, I. Mediterranean Congress of Oral and Maxillofacial Surgery, Athens, 1991. 3. Djordjevic B., Visnjic M., Visnjic Z.: „Surgical Skin Treatment of Medial Cantus, Acta Stomatologica Naisi“ 4. Djordjevic B., Brankovic LJ.: „Treatment of Defect Skin Coverage of the Hand“, II Scientific Simposium, Research in Medicine and Stomatology, October 1991, Acta Facultatis Med. Nassiensis, Vol. 11/1. 5. Djordjevic B., Buric N., Visnjic M.: „Surgical Treatment of Advanced Skin Cancer of the Scalp“. Acta Medica Medianae. 6. Djordjevic B.: „Augmentation Mammaplasty Experiences with Silicon Implants with Correction of Hypoplastic Breast“, Acta Medica Medianae. 7. Djordjevic G., Visnjic M., Visnjic Z., Burie N., Jeremic M.: „Malignant Skin Tumors of Face and Scalp – Our Experience in Reconstruction of Post-Operative Defects“, XI Congress of european Association for Cranio-Maxillofacial Surgery, Innsbruck, 1992, 9 – 13. 8. Djordjevic B., Burie N., Todorovic Lj., Otasevic M., Visnjic B., Visnjic M.: „Antral Microflora in Patients with Oroantral Communication of Different Duration“, XI Congress of European Association for Cranio-Maxillofacial Surgery, Insbruck, 1992, 9 – 13. 9. Djordjevic B.: „Surgical Treatment of Obesity“, II International Scientific Congress of Obesity, Cigota, Zlatibor, 1993. 10. Djordjevic B., Visnjic M., Buric M., Visnjic Z.: „Reconstruction of Big Skin Defects of Face and Neck“, XII Congress E.A.C.M.S., Hague, 1994. 11. Djordjevic B., Visnjic M., Buric N.: „Secondary Rhinoplasty“, XII Congress E.A.C.M.S., Hague 1994 12. Djordjevic B., Buric N., Todorovic Lj., Visnjic B., Otasevic M., Katic V., Krasic D., Jovanovic G.: „Bacteriological and Pathological Studies in Patients with Artificially Opened Maxillary Sinus“, XII Congress E.A.C.M.S., Hague 1994. 13. Djordjevic B., Visnjic M.: „Zatvaranje kutano-faringoezofagealne fistule ostrvastim pectoralis major misicno-koznim reznjem i slobodnim transplantatom koze – prikaz slucaja. 14. Djordjevic B., Visnjic M.: „Rekonstrukcija donje usne slobodnim podlakticnim reznjem. 15. Djordjevic B., Pantelic B., Panajotovic Lj.: „Carcinoma of the Anthethoracal Dermatoesophagus as the Late Complication of Dermatoesophagoplasty, ISS/SIC, August, 1997. 16. Djordjevic B., Pantelic B., Panajotovic Lj., Kozarski J., Novakovic M.: „Surgical Treatment of Tissue Defects in War Wounds“, IPSSH/IPRAS, August 1997. Published Books: 74
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1. Djordjevic b., M.D., Ph.D., Surgery of the Hand, Medicinska Knjiga, Belgrade, Yugoslavia, 1994 2. Djordjevic B., M.D., Ph.D., Plastic and Reconstructive Surgery: Principals of Anatomy and Technique, Vol. I. Atalanta International, Ltd, Belgrade, Yugoslavia, 1995. 3. Djordjevic B., M.D., Ph.D. Plastic and Reconstructive Surgery: Head and Neck, Vol. II, Atalanta International, Ltd, Belgrade, Yugoslavia, 1996 Tumors of the Skin and Subcutaneous Tissue Facial Lesions Laser and Microsurgery. 4. Djordjevic B., M.D., Ph.D., Plastic and Reconstructive Surgery, Vol. III, Atalanta international, Ltd., Belgrade, Yugoslavia, 1997 Burns Reconstruction of the Face, Scalp, Eyes Nose and Ears 5.
6. Djordjevic B., M.D., Ph.D., Plastic and Reconstructive Surgery, Vol. IV, Atalanta International Ltd.., Belgrade, Yugoslavia, 1998 Cleft Palate Cleft Lip Craniofacial Anomalies Facial Fractures Djordjevic B.,M.D.,Ph.D., Plastic and Reconstructive Surgery, Vol. V, Atalanta International Ltd.., Belgrade, Serbia 2008 Hand Surgery MEDICAL REFERENCES THOMAS S. POWERS, M.D. – general practitioner Diva Aesthetics Medical Group 2054 A Westminster Mall Westminister, CA 92863 (714) 379-5301 CRAIG ROSENBLOOM, M.D. - anesthesiologist 73-095 Alessandro Drive, Suite 1 Palm Desert, CA 92260 (760) 568-5381 MAJA RUETSCHI, M.D. – plastic surgeon 73-121 Fred Waring Drive Palm Desert, CA 92260 (760) 340-1199 ROBERT SINGLEMANN, M.D. – plastic surgeon 7345 Medical Center Drive, Suite 230 Westhills, CA 91307 818-884-7123 310- 476-7651
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Medical Advisory Board Visionary BC will constitute a Medical Advisory Board which will be comprised of select physicians that are opinion leaders and clinical experts in the practice of medicine at prestigious institutions. The Company will be seeking advice, input and support for clinical studies, participation in presentations, and co-authors of publications. The criteria for inclusion as a Medical Advisory Board is that these physicians have at least 20 years of medical practice experience in a related specialty, be extremely well-published and co-author of more than 20 publications in peer-reviewed medical literature, be viewed as an expert and recognized as an opinion leader in their field of medicine.
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