Mar. 29, 2012 issue

Page 1

T H E I N D E P E N D E N T D A I LY AT D U K E U N I V E R S I T Y

The Chronicle

THURSDAY, MARCH 29, 2012

ONE HUNDRED AND SEVENTH YEAR, ISSUE 124

WWW.DUKECHRONICLE.COM

IOM promotes ‘roadmap’ for genomics research Comprehensive plan developed to ‘do things right’ in wake of scandal by Julian Spector THE CHRONICLE

for clinical trials at a lecture Wednesday. The lack of subjects’ understanding translates to complications in the volunteering process, especially when giving informed consent—a patient’s commitment to participation in a medical trial with an understanding of what it entails. “Informed consent is not as good as we would like it to be anywhere,” Grady said. “[It] can be improved everywhere, but there is no logical reason to insist that informed consent be identical in all places.”

More rigorous safeguards can protect against errors similar to the ones caused by disgraced former Duke oncologist Dr. Anil Potti, according to recommendations by a nonprofit health advisory group. A committee of the Institute of Medicine of the National Academies released a report Friday to establish standards for genomics research and other developing medical sciences based on large quantities of data. The report was partly a result of the Potti scandal, and it suggests a framework for monitoring and ensuring research integrity in translational medicine. “We’re talking about research on the frontier…. If we’d had this document in place and the Duke institution had followed these procedures, we probably wouldn’t have had the problems that happened,” said David DeMets, a member of the IOM committee that released the report and professor of biostatistics and medical informatics at the University of Wisconsin-Madison. “But of course [the procedures] weren’t in place, and people were learning as they were going.” Because the field of genomics has only developed in the last decade—since the mapping of the human genome— there was no field-wide set of research guidelines in genomics when Potti’s work began, DeMets said. It is at the discretion of investigators and research institutions to adopt the IOM framework to reduce the risk of clinical treatments based on flawed genomic science.

SEE ETHICS ON PAGE 4

SEE IOM ON PAGE 4

TYLER SEUC/THE CHRONICLE

Julia Welch, Ross McKinney and Christine Grady, the chief of the department of bioethics at the National Institutes of Health clinical center, speak following the Nancy Weaver Emerson lectureship Wednesday.

Grady urges reform in human research by Danielle Muoio THE CHRONICLE

The way clinical studies inform patients about what they are getting involved with works no better in the U.S. than elsewhere in the world, one expert said. Patients from both developed and third world countries exhibited a similar lack of understanding of the medical research process, which limits their discernible rights, said Christine Grady, the chief of the department of bioethics at the National Institutes of Health Clinical Center. She discussed her work on subject recruitment

Two students Malaria project wins ChangeWorks comp. win Goldwater scholarships by Madeleine Clark THE CHRONICLE

From Staff Reports THE CHRONICLE

Two Duke juniors have been named Barry M. Goldwater Scholars in science, mathematics and engineering, the University announced Tuesday. Kenneth Hoehn, an Angier B. Duke scholar from Canton, Ga. and Clara Starkweather, an Angier B. Duke scholar from Athens, Ga., won the award in recognition of their undergraduate research in the sciences, according to a Duke news release Tuesday. Through the national award, Hoehn and Starkweather are eligible for up to $7,500 toward annual tuition and expenses. Hoehn and Starkweather were selected based on their academic merit and were chosen from a pool of about SEE GOLDWATER ON PAGE 10

Ward content with international career over, Page 5

ANH PHAM/THE CHRONICLE

Undergraduate entrepreneurs competed Wednesday for seed money to launch socially-conscious ventures. Four finalist teams presented at Duke Venture Forward’s second annual ChangeWorks social entrepreneurship pitch competition in Sheafer Theater Wednesday night. Following a presentation from keynote speaker Greg van Kirk, Ashoka Foundation Lemelson Fellow and the co-founder of the New Development Solutions Group, judges and voters awarded $5,000 in seed money to sophomore Katie Guidera and her venture, the Malaria Awareness Program in HaMakuya, South Africa. “I don’t think the key to solving so many problems in our world is about creating a million social entrepreneurs,” van Kirk said. “It’s about learning about how to engage with others and understand what their problems are and come up with solutions together.” Undergraduates were invited to post ideas for socially conscious start-ups on the program’s website, beginning Feb. 7. Visitors to the website voted for their favorite ideas,

Sophomore Katie Guidera presents the Malaria Awareness Program in HaMakuya, South Africa.

SEE CHANGEWORKS ON PAGE 10

ONTHERECORD

“Then everybody jumps all over everybody and the comment section looks like a meerkat enclosure in the zoo on the Fourth of July.” —Mia Lehrer in “The requisite Duke culture lament.” See column page 8

Scheyer holds on to NBA dream, Page 5


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