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Children and COVID

Children and COVID

News and views from Emory School of Medicine alumni

FALL 2020

IN TUNE TO A Different Rhythm

As Deputy Director for Public Health Service and Implementation Science at the Centers for Disease Control and Prevention (CDC), Rear Admiral Stephen C. Redd 83M spent March 11 testifying during a House Homeland Security Committee hearing on “Confronting the Coronavirus: The Federal Response.”

“As we begin to see community spread of this virus, it will be important for all of us to take action in preventing its spread through common sense public health precautions,” Redd told the committee on the day the virus’s spread was declared a pandemic, in the hearing covered by C-SPAN.

Redd had been thinking about such a threat for a while. In a podcast for the National Association of County and City Health Officials that aired in August 2019, Redd talked about the health threats that keep him awake at night: an influenza pandemic, other contagious respiratory disease outbreaks, and weather disasters related to climate change.

Redd’s words were prophetic given the events of 2020: the coronavirus pandemic, wildfires in California, and powerful hurricanes. “The nature of our work is to be ready for the threats we can identify and be able to pivot to respond to events that are of even greater consequence,” said Redd in the podcast. “When we’re in an emergency response, we can fail to accept or appreciate the uncertainties, and we think we know more than we do. Maintaining a sense of humility and contingency is really important.”

Redd is poised to retire from CDC this year. One lesson he has carried with him throughout his 35-year career is that medicine and public health have distinct tempos.

He became aware of the difference following his second year of study at Emory School of “My training at Emory was a great experience, I had Medicine, when he held the chance to rotate through Grady, the Atlanta VA a summer job in CDC’s Medical Center, and Emory’s hospitals.” reproductive health division. He happened to work there in 1981, when the first cases of “There was a different rhythm at AIDS were diagnosed. “CDC was a much CDC,” Redd says. “During my residency smaller place then,” says Redd. “Even and at Grady, I stayed up nights taking though I didn’t work on HIV, I was able care of patients The hours were long and to attend lectures on pneumocystis and the feedback from patients was immediKaposi’s sarcoma. Everyone at CDC was ate. As an EIS officer, I investigated disease trying to figure out how to deal with the outbreaks, which was totally different.” growing AIDS epidemic. It gave me a taste Shortly after completing EIS training, of something different that I could do Redd traveled to West Africa to assess the with my medical degree.” feasibility of conducting a pneumococcal

Redd went on to graduate from vaccine trial in Senegal. Following EIS, Emory and complete a medicine res- Redd remained at CDC, leading childidency at Johns Hopkins University hood survival projects (acute respiratory School of Medicine. In 1985, he returned infections and malaria) in Africa and to Atlanta, his hometown, and CDC to efforts to eliminate measles in the United serve as an officer with the Epidemic States (achieved in 2000). Intelligence Service (EIS). For some time, When terrorists attacked the US in he also volunteered as an attending 2001, Redd was working in CDC’s National on the medicine service at Grady Center for Environmental Health to Memorial Hospital. reduce the burden of asthma. A few weeks

later, he was on a charter plane to Trenton, New Jersey, to assist with the emergency response to the anthrax attacks following 9/11. Letters containing anthrax had been sent from a Trenton post office and thus put its workers at risk. The response brought home another important lesson for Redd: knowing when to pivot.

“On our first day in New Jersey, a Sunday, we went to the post office and swabbed the noses of employees who had worked there,” he says. “The next day, we learned that all the tests were negative and that our method for determining exposure was inadequate. We then contacted hospitals in New Jersey and asked them to send a daily report of suspected cases of anthrax, either from the emergency room, the intensive care unit, or the laboratory. We developed questionnaires that the hospitals completed and faxed to us every day. That made it easier to determine if anyone had been exposed and get them on treatment as quickly as possible.”

Redd’s response skills would be further tested as director of the Influenza Coordination Unit. CDC formed the unit in 2006 based on national and global concerns that the H5N1 avian influenza virus could become a human pandemic. At the time, the virus had spread in birds from Asia to Africa and occasionally in people. The human mortality rate was 60%.

“The spread of the H5N1 virus in humans was unprecedented and led to a global effort to prepare for a possible pandemic,” says Redd. “CDC was on the leading edge of that effort. That’s when the Influenza Coordination Unit was formed.”

Its first rule of operation: practice, practice, practice. Working with ex-military experts, CDC staff wrote a response plan grounded in different exercise theories. In 2007 and 2008, the unit conducted five real-life exercises in the agency’s Emergency Operations Center.

During each exercise, a group of experts worked “behind the curtain,” injecting information to which staff had to respond. “We set up our daily rhythm,” says Redd. “We held mock press conferences and daily briefings, knowing that the scenario could change at any moment. Through those exercises, we learned a lot about what we would have to do during a real pandemic.”

In 2009, when the first cases of H1N1 influenza were reported, CDC went into action. “We activated the Emergency Operations Center but still weren’t sure

5 THINGS TO KNOW ABOUT

Stephen Redd

1Redd will soon retire as deputy director for public health service and implementation science at the CDC. He oversees four areas: the Office of Minority Health and Health Equity, the Center for Global Health, the Center for Preparedness and Response, and the Center for State, Tribal, Local, and Territorial Support. He is also a rear admiral in the US Public Health Service and an assistant surgeon general. 2 Born in Augusta and reared in Atlanta, he majored in history at Princeton University and went on to medical school at Emory. 3 His late father, Stephen S. Redd 63MR, was a pediatrician. 4 His wife, Atlanta radiologist Judith Chezmar, did a fellowship at Emory. They have two grown children. 5 Redd is an avid runner and eclectic reader. Recent book picks include The Silmarillion (a prequel to the Lord of the Rings series by J.R.R. Tolkien), Zen and the Art of

Motorcycle Maintenance, and a new translation of Beowulf.

how severe the disease would be,” says Redd. “The first two patients in the US had already recovered by the time they were identified. We suspected there was widespread transmission but didn’t know the severity.”

The seminal moment occurred late on a Thursday afternoon when CDC received a report from Canada where specimens from people hospitalized in Mexico had been tested and confirmed as H1N1 cases. “Some of the people who subsequently died were among the cases,” says Redd. “There was more severe disease in Mexico than we had seen in the US. From that moment on, everything changed.”

Emergency responses, drill sessions and real ones, highlight perhaps the biggest challenge of all—making a decisive call to protect individuals and populations.

“The reality is you have to make decisions without having all of the information that you would like to have,” Redd explains. “If you delay, that’s a decision in itself—it’s deciding not to do something. There’s a timeframe for every decision, from martialing the best evidence you have to making a decision when it has to be made.”

Two decades have passed since measles was eliminated in the US. Yet measles cases have resurged in recent years. In 2019, more than 1,000 cases were confirmed in 31 states—the highest number since 1992.

Key factors are driving the increase. Although global measles control has improved immeasurably, the disease is still common in many countries. Unvaccinated travelers to those countries bring the disease back to the US, where it spreads easily among unvaccinated people. Many have avoided immunization, believing it is unsafe.

To combat the resurgence, CDC has taken steps to remove financial barriers to vaccination and provide constant assurance that the MMR (measles, mumps, rubella) vaccine is safe and effective.

“The vaccination coverage for measles has been over 90% in the past 15 years or so,” says Redd. “Ultimately, the global elimination of measles is the answer to ending the outbreaks we are having here. It’s hard to say how soon that day will come. As long as measles can be imported, we’ll be at risk in the US.” —Pam Auchmutey

During medical school, Levy founded a national health education campaign called Music Inspires Health, teaming up music industry celebrities with physicians, medical students, and public health experts.

WHERE IN THE (VIRTUAL) WORLD

If ever there were a time to help people reduce feelings of stress, anxiety, and isolation, this is it. Who knew it would involve playing a cello at a baseball field, though?

And that’s exactly what School of Medicine alumnus Benjamin Levy 08M decided to give viewers during the TEDxWrigleyville livestream event, “Humanity, A View from Inside the Pandemic,” on Sunday, June 28, from Wrigley Field in Chicago.

Levy, division head of gastroenterology at Mount Sinai Hospital, Holy Cross Hospital, and Schwab Rehabilitation Hospital in Chicago as well as founder of a refugee clinic, brought music to the frontlines of COVID-19 as a featured TEDx speaker, an independently organized event licensed by TED.

Levy’s talk, “Motivating Health Education with Music,” featured cello performances from himself and internationally acclaimed cellist Yo-Yo Ma, whom Levy has known since he was nine years old. He arranged for Ma’s performance as an extension of Ma’s #SongsofComfort series during the pandemic.

Using examples, Levy discussed how the rock band Queen and Elton John innovated HIV prevention campaigns through live concerts and made HIV prevention “cool.” He talked about how music can empower audiences and break down barriers to ensure messages are shared broadly.

Levy also spoke about his own efforts to use music to promote health, such as the “Music Inspires Health” concert tour he organized during medical school at Emory, and weekly virtual concert series, “Cocktails and Concerts,” he founded and organized by introducing collaborations between musicians and doctors and nurses on the frontlines of the pandemic.

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Plan big.

Red Sky at Night Emtriva—the revolutionary medication for the treatment of HIV—was invented by Emory scientists.

Robert Taylor, director of cardiology, captured this fiery sunset

and a slice of the Atlanta skyline from the physicians’ parking This little pill changed the world.

deck of Emory University Hospital.

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