Available Phosphatidylserine Most commercial products are made from cabbage or soybeans due to the risk of mad cow disease in bovine brain tissue and the products have a similar, but not identical chemical structure to the bovine derived supplements. The Food and Drug Administration claims that phosphatidylserine molecule from soy lecithin contains mainly polyunsaturated acids, while that from bovine brain cortex contains mainly saturated fatty acids and monounsaturated fatty acids and long-chain polyunsaturated fatty acids.
A preliminary rats study has indicated that the soy derived phosphatidylserine supplement was as effective as the bovine derived supplement in one of three behavioral tests. There is studying in humans finding that a daily supplement of soybean-derived phosphatidylserine does not affect memory or in older individuals with memory complaints. Phosphatidylserine can be to improve performance in athletes, endocrine response to exercise stress, and decrease muscle damage in athletes involved in cycling, weight training, golf and endurance running. It has showed to be an effective supplement for combating exercise- induced stress by blunting the exercise- induced increase in cortisol levels in a dose dependent manner. The supplementation of PS promotes a desirable hormonal balance for players and it can attenuate the physiological deterioration that accompanies overtraining or overstretching. It can enhance mood in young people during mental stress and to improve accuracy during tee-off.
PS supplements were derived from bovine cortex while soy-derived PS supplements have been used as an alternative due to the risk of potential transfer of infectious diseases, and soy-derived PS is designated recognized as safe by the FDA. The safety report in 2002 determined supplementation in elder people at a dosage of 200 mg three times per day and it is safe. By condensing the amino acid serine, it is biosynthesized in bacteria. In mammals, It is produced by base-exchange reactions can also give rise to phosphatidylethanolamine and phosphatidylcholine.