Scientific Solutions for Life
Product Catalog
American Laboratory Products Company (ALPCO) was founded in 1991 as an importer and distributor of immunoassay based products for the North American life science markets. Our origin began through an exclusive partnership with a European manufacturer, Bühlmann Laboratories, located just outside of Basel Switzerland. Over the past two decades, ALPCO has become a premier channel representing over 60 collaborating partners from around the globe. In late 2008, we launched our organically developed product line focused in the area of diabetes and obesity research, while also remaining true to our roots by continuing to provide “Immunoassays Beyond the Ordinary.” As ALPCO has evolved, we’ve expanded our offering into applications for HPLC, LC-MS/ MS, purified antibodies, recombinant proteins and most recently flow cytometry based reagents. This next year will prove exceptionally productive as our offering will continue to grow by over 400 new products, with a specific development focus in our new STELLUX line of chemiluminescent based detection systems. While our vision has expanded to serve a broader segment of life science research and healthcare professionals dedicated to improving patient outcomes, our mission to deliver “Scientific Solutions for Life” remains the same.
- Sean G. Conley, President
Table of Contents Allergy
4
Neurobiology
90
98
Bone Metabolism
20
Toxicology
CVD & Oxidative Stress
26
Flow Cytometry
106
Diabetes & Obesity
36
Accessories & Equipment
124
Endocrinology
46
Index
126
Gastroenterology
56
Ordering Information
132
Immunology
64
Website
Resources
ALPCO continually strives to provide you with
Our knowledgeable and responsive technical support
informative and resourceful content instantly via our
team is here to help you. View the Resources section of
website. The Clinical and Research sections allow you to
our website for answers to frequently asked questions,
download tailored information in your area of interest,
technical tips and interactive tools. You can submit
or learn more about featured products and biomarkers
an inquiry at any time and our dedicated technical
in our “Did You Know?” segments. For more detailed
representatives will assist in finding an optimal solution to
information on a product you can visit the product pages
your testing needs.
for specifications, protocols, or MSDS as well as check pricing and order online 24/7. You’ll also want to visit for updates on News, Events, and promotional information.
Allergy & Infectious Disease Gastroenterology
4
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Allergy & Infectious Disease The immune system protects our body against several factors including allergens, harmful pathogens and foreign particles. Allergies involve an exaggerated response of the immune system and are among the most common chronic conditions worldwide. Infectious disease agents are also one of the leading contributors to debilitating and sometimes fatal conditions. Therefore, researchers and practitioners look to understand interactions between microbes and the immune system in order to 5
translate this knowledge into treatment, control and prevention of conditions caused by allergies and infectious disease.
Allergy Testing Identification of allergens causing immediate type
However, results from these tests are often unclear and
reactions can be a very difficult task for allergists.
inconclusive due to cross reactivity, low sensitivity, or
The method of investigation usually starts with patient
non-IgE mediated allergies, making a provocation test
anamnesis followed by skin and specific IgE tests.
necessary, bearing the risk of an anaphylactic event.
Allergy & Infectious Disease Gastroenterology FlowCAST® Basophil Activation Assays
Upon allergen contact, sensitized basophils degranulate
ALPCO is the exclusive distributor of BÜHLMANN
and express the cell surface marker CD63. In addition,
Laboratories’ FlowCAST® allergy assays and allergens.
the surface marker CD203c is upregulated. By labeling
FlowCAST® offers an easy, fast and reliable solution
specific antibodies against these surface markers with
for allergy determination utilizing basophil activation
fluorochromes, their relative number can be measured
measurement via flow cytometry. In vitro basophil
with any four parameter flow cytometer.
activation testing reduces the risk of an anaphylactic event and patient discomfort while also providing a
Selection of Basophils: Basophils constitutively express
sensitive, quantitative measurement of non-IgE mediated
the eotaxin receptor CCR3 allowing for a robust and
reactions which serum IgE methods are
accurate selection of cells. CCR3 is measured via a PE-
unable to achieve.
fluorescence labeled monoclonal antibody. This gating of
6
basophil cells is significantly easier than with any other commercially available basophil activation test.
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Adenovirus IgA ELISA
20-AVAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Adenovirus IgG ELISA
20-AVGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Adenovirus IgM ELISA
20-AVMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 15m
Anti-Cag-A IgG ELISA
27-GD33
Cut-off: See Protocol
6.25 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Candida IgA ELISA
27-GD19
12.5–100 U/mL
0.5 U/mL
5 µL
Serum
1h 10m
Anti-Candida IgG ELISA
27-GD22
12.5–100 U/mL
0.5 U/mL
5 µL
Serum
1h 10m
Anti-Candida IgM ELISA
27-GD20
Cut-off: See Protocol
See Protocol
5 µL
Serum
1h 40m
Anti-Casein IgA ELISA
27-GD42
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
20-CGGHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 45m
27-GD84
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Chlamydia IgG ELISA Anti-Cytomegalovirus IgG ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Activation of Basophils: CD63 and CD203c are
Stimulation Controls: The FlowCAST® assays provide
currently the best validated basophil activation
two stimulation controls, anti-FcεRI and fMLP. The
markers directly linked to basophil degranulation.
first control, anti-FcεRI, is a highly specific monoclonal
The FlowCAST® assay detects CD63 via a FITC-
antibody binding to IgE receptor. The second control,
fluorescence labeled monoclonal antibody, while the
a tripeptide fMLP, activates basophils by a non-
FlowCAST® High Sensitivity assay detects both CD63
immunological method.
and CD203c via a tandem dye PE-647 fluorescence Allergens: BÜHLMANN offers a portfolio of over 150
labeled monoclonal antibody.
quality controlled and standardized allergens for use with the basophil activation assays.
7
View basophil activation assays 01-FK-CCR and 01-FK-HSBAT on page 10
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Anti-Cytomegalovirus IgM ELISA
27-GD85
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Gliadin IgA ELISA
27-GD17
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
Anti-Gliadin IgA/IgG ELISA
27-GD77
6.25–100 U/mL
0.5 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Gliadin IgG ELISA
27-GD16
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
22-E10
10–50 mIU/mL
0.1 IU/mL
10 µL
Plasma, Serum
4h
Anti-HAV IgG ELISA
68-4AGE3
Cut-off: See Protocol
See Protocol
10 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HAV IgM ELISA
68-4AME3
Cut-off: See Protocol
See Protocol
5 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Anti-HCV ELISA
68-4NAE3
Cut-off: See Protocol
See Protocol
100 µL
Plasma, Serum
1h 45m
27-GD08
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-HAV ELISA
Anti-Helicobacter Pylori IgA ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Allergy & Infectious Disease Gastroenterology Description
8
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Anti-Helicobacter Pylori IgG ELISA
27-GD01
6.25–100 U/mL
6.25 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori IgM ELISA
27-GD124
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
50m
Anti-Helicobactor Pylori ELISA
30-6920
Cut-off: See Protocol
See Protocol
100 mg
Stool
3h
Anti-Herpes-1 IgG ELISA
27-GD86
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Herpes-1/2 IgM ELISA
27-GD88
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Herpes-2 IgG ELISA
27-GD87
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Ovalbumin IgA ELISA
27-GD40
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Ovalbumin IgG ELISA
27-GD41
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Ps-Aeruginosa IgA ELISA
27-GD18
6.25–100 U/mL
1.2 U/mL
100 µL
Serum
1h 10m
Anti-Ps-Aeruginosa IgG ELISA
27-GD07
6.25–100 U/mL
0.75 U/mL
100 µL
Serum
1h 10m
Anti-Rubella IgG ELISA
27-GD82
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Rubella IgM ELISA
27-GD83
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Soya IgA ELISA
27-GD44
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Aspergillus IgG Antibody ELISA
27-GD29
12.5–100 U/mL
0.17 U/mL
100 µL
Serum
1h 10m
Bordetella Pertussis IgA ELISA
20-BPAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 15m
Bordetella Pertussis IgG ELISA
20-BPGHU-E01 *
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Bordetella Pertussis IgM ELISA
20-BPMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Brucella IgG ELISA
20-BRGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Brucella IgM ELISA
20-BRMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
C. Trachomatis IFA
50-580-01
See Protocol
See Protocol
10 µL
Serum
1h
30-7010
1–120 ng/mL
1 ng/mL
2 mL
Urine
Overnight
01-EK-CAST
50–3,200 pg/mL
20 pg/mL
2 mL
Whole Blood
2h 30m
Casomorphin ELISA CAST® ELISA (Leukotriene Function)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
West Nile Exposure to West Nile Virus (WNV) causes a disease with a number of symptoms including encephalitis. It is a potentially neuroinvasive agent that causes asymptomatic infection and fever in humans. ALPCO’s FDA registered West Nile Virus IgM ELISA employs a recombinant WNV antigen and can be used as a rapid serological marker for WNV infection.
View west nile assays 65-WNGHU-E01 and 65-WNMHU-E01 on page 12
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
01-EK-CAST5
50–3,200 pg/mL
20 pg/mL
2 mL
Whole Blood
2h 30m
Chlamydia IgA IFA
50-513-01
See Protocol
See Protocol
10 µL
Serum
1h
Chlamydia IgG IFA
50-511-01
See Protocol
See Protocol
10 µL
Serum
1h
Chlamydia IgM IFA
50-512-01
See Protocol
See Protocol
5 µL
Serum
1h
Chlamydia Trachomatis IgA ELISA
20-CTAHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 45m
Chlamydia Trachomatis IgM ELISA
20-CTMHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 45m
30-8500
0–15.65 U/mL
0.052 U/mL
50 µL
Serum
4h 20m
Dengue IgG ELISA
20-DEGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Dengue IgM ELISA
20-DEMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Dengue NS1 ELISA
65-DENHU-E01
See Protocol
See Protocol
50 µL
Serum
1h 51m
Echinococcus Granulosus IgG ELISA
20-EGGHU-E01 *
Cut-off: See Protocol
See Protocol
10 µL
Serum
20m
Epstein Barr Virus Nuclear Antigen IgG ELISA
20-ENGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Epstein Barr Virus Nuclear Antigen IgM ELISA
20-ENMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Epstein Barr Virus Viral Capsid Antigen IgA ELISA
20-EVAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Citrate Plasma, Serum
1h 45m
Epstein Barr Virus Viral Capsid Antigen IgG ELISA
20-EVGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Epstein Barr Virus Viral Capsid Antigen IgM ELISA
20-EVMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Fasciola Hepatica IgG ELISA
20-FHGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
CAST® ELISA Jumbo (Leukotriene Function)
DAO ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
9
Allergy & Infectious Disease Gastroenterology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
01-FK-HSBAT ^
See Protocol
See Protocol
100 µL
Whole Blood
1h
01-FK-CCR
See Protocol
See Protocol
50 µL
Whole Blood
30m
Herpes Simplex Virus 1 IgG ELISA
20-HSGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Herpes Simplex Virus 1 IgM ELISA
20-HSMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Herpes Simplex Virus 1/2 IgG ELISA
20-HG2HU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Herpes Simplex Virus 1/2 IgM ELISA
20-HM2HU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Herpes Simplex Virus 2 IgG ELISA
20-H2GHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Herpes Simplex Virus 2 IgM ELISA
20-H2MHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Histamine ELISA
17-HISHU-E01
0.3–30 ng/mL
See Protocol
25 µL
Plasma, Urine
Overnight
Histamine ELISA
32-5890
0.39–50 nM
0.05 nM
200 µL
Biological Fluids, Cell Culture, Plasma, Urine
Overnight
Histamine ELISA (Cell Culture)
17-HISCC-E01
0.5–50 ng/mL
0.2 ng/mL
20 µL
Cell Culture, Urine
1h
17-HISHU-E01-FOOD
See Protocol
0.15 µg/L
See Protocol
Food
2h
Histamine ELISA (Stool)
17-HISHU-E01-STL
0.5–50 ng/mL
6.1 ng/g
See Protocol
Stool
2h
Histamine Research ELISA
17-HISRT-E01-RES
0.3–30 ng/mL
0.2 ng/mL
10 µL
EDTA Plasma
Overnight
Influenza A IgA ELISA
20-IAAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Influenza A IgG ELISA
20-IAGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Influenza A IgM ELISA
20-IAMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Influenza B IgA ELISA
20-IBAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Influenza B IgG ELISA
20-IBGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Influenza B IgM ELISA
20-IBMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Japanese Encephalitis IgG ELISA
65-JEGHU-E01
See Protocol
See Protocol
4 µL
Serum
2h 16m
Japanese Encephalitis IgM ELISA
65-JEMHU-E01
See Protocol
See Protocol
4 µL
Serum
3h 16m
20-MEMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
FlowCAST Highsens® High Sensitivity Basophil Activation Test FlowCAST® Basophil Activation Test
10
Histamine ELISA (In Food)
Measles IgM ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Mumps IgG ELISA
20-MUGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Mumps IgM ELISA
20-MUMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Mycobacterium Tuberculosis IgG ELISA
65-TBGHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Mycobacterium Tuberculosis IgM ELISA
65-TBMHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Mycoplasma Hominis IgA ELISA
20-MHAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Mycoplasma Hominis IgG ELISA
20-MHGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Mycoplasma Hominis IgM ELISA
20-MHMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
2h 25m
Orientia Tsutsugamushi IgG ELISA
65-OTGHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Orientia Tsutsugamushi IgM ELISA
65-OTMHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Parvovirus B 19 IgG ELISA
20-PBGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Parvovirus B 19 IgM ELISA
20-PBMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Respiratory Syncytial Virus IgA ELISA
20-RSAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Respiratory Syncytial Virus IgG ELISA
20-RSVHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
2h
Respiratory Syncytial Virus IgM ELISA
20-RSMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Syphilis IgG ELISA
20-SYGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Syphilis IgM ELISA
20-SYMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Syphilis Screen ELISA
20-SYSHU-E01
Cut-off: See Protocol
See Protocol
20 µL
Plasma, Serum
2h 30m
Syphilis Screen IgG/IgM ELISA
20-TPSHU-E01
Cut-off: See Protocol
See Protocol
100 µL
Plasma, Serum
1h 45m
Tetanus Toxin IgG ELISA
20-TETHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Toxoplasma Gondii IgA ELISA
20-TGAHU-E01
Cut-off: See Protocol
See Protocol
20 µL
Serum
1h 15m
Toxoplasma Gondii IgM ELISA
20-TGMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
27-GD80
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
See Protocol
ToxoPlasma IgG Ab ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
11
Allergy & Infectious Disease Gastroenterology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Ureaplasma Urealyticum IgA ELISA
20-UUAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Ureaplasma Urealyticum IgG ELISA
20-UUGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
2h 20m
Ureaplasma Urealyticum IgM ELISA
20-UUMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Varicella Zoster IgA ELISA
20-VZAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Varicella Zoster IgG ELISA
20-VZGHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
Varicella Zoster IgM ELISA
20-VZMHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h 45m
65-VILHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 16m
West Nile Virus IgG ELISA
65-WNGHU-E01
See Protocol
See Protocol
4 µL
Serum
2h 15m
West Nile Virus IgM ELISA
65-WNMHU-E01 *
See Protocol
See Protocol
4 µL
Serum
3h 16m
Visceral Leishmaniasis ELISA
12
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Allergen Category Sub-Category
Description
Catalog Number
DRUGS
Adjuvants
Carboxymethylcellulose
05-BAG2-CE466
DRUGS
Adjuvants
PEG-4000
05-ABG2-CPEG
DRUGS
Analgesic
Acetaminophen
05-BAG2-C55
DRUGS
Analgesic
Diclofenac
05-BAG2-C52
DRUGS
Analgesic
Dipyrone/Metamizole
05-BAG2-C59
DRUGS
Analgesic
Ibuprofen
05-BAG2-C53
DRUGS
Analgesic
Indomethacin
05-BAG2-C54
DRUGS
Analgesic
Lys-Aspirin
05-BAG2-C51
DRUGS
Analgesic
Mefenamic Acid
05-BAG2-C56
DRUGS
Analgesic
Naproxen
05-BAG2-CNAP
DRUGS
Analgesic
Phenylbutazone
05-BAG2-C57
DRUGS
Analgesic
Propyphenazone
05-BAG2-C58
DRUGS
Antibiotic
Amoxicillin
05-BAG2-C204
DRUGS
Antibiotic
Ampicillin
05-BAG2-C203
DRUGS
Antibiotic
Benzylpenicilloyl + - Acid, MDM
05-BAG2-C12
DRUGS
Antibiotic
Benzylpenicilloyl -Polylysin, PPL
05-BAG2-C11
DRUGS
Antibiotic
Cefaclor
05-BAG2-C34
DRUGS
Antibiotic
Cefamandole
05-BAG2-C31
DRUGS
Antibiotic
Cefazolin
05-BAG2-C32
DRUGS
Antibiotic
Cefuroxime
05-BAG2-C33
DRUGS
Antibiotic
Cephalosporin C
05-BAG2-C3
DRUGS
Antibiotic
Cetriaxone
05-BAG2-C35
DRUGS
Antibiotic
Ciprofloxacin
05-BAG2-C81
DRUGS
Antibiotic
Clarythromycin
05-BAG2-CCLA
DRUGS
Antibiotic
Clavulanic Acid
05-BAG2-CCLAV
DRUGS
Antibiotic
Levofloxacin
05-BAG2-C36
DRUGS
Antibiotic
Penicillin G
05-BAG2-C1
DRUGS
Antibiotic
Penicillin V
05-BAG2-C2
DRUGS
Antibiotic
Rifampicin
05-BAG2-CRIF
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
All Allergens are Health Canada Licensed
13
Allergy & Infectious Disease Gastroenterology Allergen Category Sub-Category
14
Description
Catalog Number
DRUGS
Antibiotic
Sulfamethoxazole
05-BAG2-C61
DRUGS
Antibiotic
Tetracycline
05-BAG2-C75
DRUGS
Antibiotic
Trimethoprim
05-BAG2-C62
DRUGS
Antiseptic
Chlorhexidine
05-BAG2-CCHX
DRUGS
Contrast Media
Iobitridol
05-BAG2-CIOBI
DRUGS
Contrast Media
Iodixanol
05-BAG2-CIODI
DRUGS
Contrast Media
Iohexol
05-BAG2-CIOHE
DRUGS
Contrast Media
Iomeprol
05-BAG2-CIOME
DRUGS
Contrast Media
Iopamidol
05-BAG2-CIOPA
DRUGS
Contrast Media
Iopromide
05-BAG2-CIOPR
DRUGS
Contrast Media
Ioxaglate
05-BAG2-CIOXA
DRUGS
Contrast Media
Ioxitalamate
05-BAG2-CIOXI
DRUGS
Local Anesthetic
Articaine
05-BAG2-CART
DRUGS
Local Anesthetic
Bupivacaine
05-BAG2-CBUP
DRUGS
Local Anesthetic
Lidocaine
05-BAG2-CLID
DRUGS
Local Anesthetic
Mepivacaine
05-BAG2-CMEP
DRUGS
Myorelaxant
Atracurium
05-BAG2-CATR
DRUGS
Myorelaxant
Cisatracurium
05-BAG2-CCAT
DRUGS
Myorelaxant
Mivacurium
05-BAG2-CMIV
DRUGS
Myorelaxant
Pancuronium
05-BAG2-CPAN
DRUGS
Myorelaxant
Propofol
05-BAG2-CPRO
DRUGS
Myorelaxant
Rocuronium
05-BAG2-CROC
DRUGS
Myorelaxant
Suxamethonium
05-BAG2-CSUX
DRUGS
Myorelaxant
Vecuronium
05-BAG2-CVEC
DRUGS
Proton Pump Inhibitors
Esomeprazole
05-BAG2-CESO
DRUGS
Proton Pump Inhibitors
Lansoprazole
05-BAG2-CLAN
DRUGS
Proton Pump Inhibitors
Omeprazole
05-BAG2-COMe
DRUGS
Proton Pump Inhibitors
Pantoprazole
05-BAG2-CPANT
DRUGS
Proton Pump Inhibitors
Rabeprazole
05-BAG2-CRAB
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
All Allergens are Health Canada Licensed
Allergen Category Sub-Category
Description
Catalog Number
ENVIRONMENTAL/OCCUPATIONAL
Environmental/Occupational
Chloramine-T
05-BAG-K85
ENVIRONMENTAL/OCCUPATIONAL
Environmental/Occupational
Latex
05-BAG-K82
ENVIRONMENTAL/OCCUPATIONAL
Environmental/Occupational
Phtalic Anhydride/Acid
05-BAG-K79
ENVIRONMENTAL/OCCUPATIONAL
Environmental/Occupational
Îą-Amylase
05-BAG-K87
FOOD
Egg
Egg White
05-BAG-F1
FOOD
Egg
Egg Yolk
05-BAG-F75
FOOD
Fish/Meat
Anisakis
05-BAG-P4
FOOD
Fish/Meat
Beef
05-BAG-F27
FOOD
Fish/Meat
Codfish
05-BAG-F3
FOOD
Fish/Meat
Crab
05-BAG-F23
FOOD
Fish/Meat
Oyster
05-BAG-F290
FOOD
Fish/Meat
Pork
05-BAG-F26
FOOD
Fish/Meat
Shrimp
05-BAG-F24
FOOD
Fish/Meat
Squid
05-BAG-F258
FOOD
Fruit/Vegetable
Carrot
05-BAG-F31
FOOD
Fruit/Vegetable
Celery
05-BAG-F85
FOOD
Fruit/Vegetable
Orange
05-BAG-F33
FOOD
Fruit/Vegetable
Peach
05-BAG-F95
FOOD
Fruit/Vegetable
Tomato
05-BAG-F25
FOOD
Grain
Baker's Yeast
05-BAG-F45
FOOD
Grain
Barley Flour
05-BAG-F6
FOOD
Grain
Maize
05-BAG-F8
FOOD
Grain
Maize Starch
05-BAG-F81
FOOD
Grain
Oat Flour
05-BAG-F7
FOOD
Grain
Rice
05-BAG-F9
FOOD
Grain
Rye Flour
05-BAG-F5
FOOD
Grain
Wheat
05-BAG-F4
FOOD
Milk/Milk Product
Casein
05-BAG-F78
FOOD
Milk/Milk Product
Cow Milk
05-BAG-F2
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
All Allergens are Health Canada Licensed
15
Allergy & Infectious Disease Gastroenterology Allergen Category Sub-Category
16
Description
Catalog Number
FOOD
Milk/Milk Product
α-Lactalbumin
05-BAG-F76
FOOD
Milk/Milk Product
β-Lactoglobulin
05-BAG-F77
FOOD
Seed/Bean/Nut
Almond
05-BAG-F20
FOOD
Seed/Bean/Nut
Cashew Nut
05-BAG-F202
FOOD
Seed/Bean/Nut
Hazelnut
05-BAG-F17
FOOD
Seed/Bean/Nut
Peanut
05-BAG-F13
FOOD
Seed/Bean/Nut
Peanut nARA H 1
05-BAG2-ARAH1
FOOD
Seed/Bean/Nut
Peanut nARA H 2
05-BAG2-ARAH2
FOOD
Seed/Bean/Nut
Peanut nARA H 6
05-BAG2-ARAH6
FOOD
Seed/Bean/Nut
Sesame
05-BAG-F10
FOOD
Seed/Bean/Nut
Soybean
05-BAG-F14
FOOD ADDITIVES
Food Additive
Amaranth
05-BAG2-CE123
FOOD ADDITIVES
Food Additive
Brilliant Black BN
05-BAG2-CE151
FOOD ADDITIVES
Food Additive
Chromotrope B
05-BAG2-CE122
FOOD ADDITIVES
Food Additive
Erythosine
05-BAG2-CE127
FOOD ADDITIVES
Food Additive
Glutamate
05-BAG2-CE621
FOOD ADDITIVES
Food Additive
Indigo Carmine
05-BAG2-CE132
FOOD ADDITIVES
Food Additive
Methylene Blue
05-BAG2-C105
FOOD ADDITIVES
Food Additive
New Coccine
05-BAG2-CE124
FOOD ADDITIVES
Food Additive
Patent Blue V
05-BAG2-CE131
FOOD ADDITIVES
Food Additive
Potassium-Metabisulfite
05-BAG2-C113
FOOD ADDITIVES
Food Additive
Quinoline Yellow
05-BAG2-CE104
FOOD ADDITIVES
Food Additive
Salicylic Acid
05-BAG2-C114
FOOD ADDITIVES
Food Additive
Sodium-Benzoate
05-BAG2-C111
FOOD ADDITIVES
Food Additive
Sodium-Nitrite
05-BAG2-C112
FOOD ADDITIVES
Food Additive
Sorbic Acid
05-BAG2-CE202
FOOD ADDITIVES
Food Additive
Sunset Yellow FCF
05-BAG2-CE110
FOOD ADDITIVES
Food Additive
Tartrazine
05-BAG2-C103
Grass
Bermuda Grass
05-BAG-G2
INHALANTS
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
All Allergens are Health Canada Licensed
Allergen Category Sub-Category
Description
Catalog Number
INHALANTS
Grass
Cultivated Rye Grass
05-BAG-G12
INHALANTS
Grass
Orchard Grass
05-BAG-G3
INHALANTS
Grass
Perennial Rye Grass
05-BAG-G5
INHALANTS
Grass
Timothy Grass
05-BAG-G6
INHALANTS
Mite/Animal/Insect
Acarus siro
05-BAG-D70
INHALANTS
Mite/Animal/Insect
Cat Epithelium
05-BAG-E1
INHALANTS
Mite/Animal/Insect
D. farinae
05-BAG-D2
INHALANTS
Mite/Animal/Insect
D. pteronyssinus
05-BAG-D1
INHALANTS
Mite/Animal/Insect
Dog Epithelium
05-BAG-E2
INHALANTS
Mold
Alternaria tenuis
05-BAG-M6
INHALANTS
Mold
Aspergillus fumigatus
05-BAG-M3
INHALANTS
Mold
Candida albicans
05-BAG-M5
INHALANTS
Mold
Cladosporium herbarum
05-BAG-M2
INHALANTS
Mold
Penicillium notatum
05-BAG-M1
INHALANTS
Tree
Common Birch
05-BAG-T3
INHALANTS
Tree
Hazel
05-BAG-T4
INHALANTS
Tree
Oak
05-BAG-T7
INHALANTS
Tree
Olive
05-BAG-T9
INHALANTS
Weed
Common Ragweed
05-BAG-W1
INHALANTS
Weed
Mugwort
05-BAG-W6
INHALANTS
Weed
Parietaria Officinalis
05-BAG-W19
INHALANTS
Weed
Ribwort/Plantain
05-BAG-W9
INSECT VENOMS
Crossreactive Carbohydrate Determinants
Bromelain
05-BAG-K202
INSECT VENOMS
Crossreactive Carbohydrate Determinants
HRP
05-BAG-K225
INSECT VENOMS
Insect Venom
European Hornet
05-BAG2-I75
INSECT VENOMS
Insect Venom
Honey Bee Venom
05-BAG2-I1
INSECT VENOMS
Insect Venom
Honey Bee Venom Check
05-BAG2-I1CHK
INSECT VENOMS
Insect Venom
Paper Wasp Venom
05-BAG2-I4
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
All Allergens are Health Canada Licensed
17
Allergy & Infectious Disease Gastroenterology Allergen Category Sub-Category
18
Description
Catalog Number
INSECT VENOMS
Insect Venom
Yellow Jacket Venom
05-BAG2-I3
INSECT VENOMS
Insect Venom
Yellow Jacket Venom Check
05-BAG2-I3CHK
RECOMBINANT ALLERGENS
Recombinant Allergen
FEL D 1 (Cat Major Allergen)
05-BAG2-FELD1
RECOMBINANT ALLERGENS
Recombinant Allergen
MAL D 1 (Apple Major Allergen)
05-BAG2-MALD1
RECOMBINANT ALLERGENS
Recombinant Allergen
TRI A 12 (Wheat Profilin)
05-BAG2-TRIA12
RECOMBINANT ALLERGENS
Recombinant Allergen
ZEA M 12 (Maize Profilin)
05-BAG2-ZEAM12
ALLERGEN MIXES
Allergen Mix
6 Grass Mix (Orchard, Meadow fescue, Perenial rye, Timothy, Meadow, Velvet grass)
05-BAG-GX1
ALLERGEN MIXES
Allergen Mix
Food Colorants I Mix (Quinoline yellow, Sunset yellow FCF, Chromotrope B, Amaranth, New coccine)
05-BAG-C101
ALLERGEN MIXES
Allergen Mix
Food Colorants II Mix (Erythrosine, Patent blue V, Indigo carmine, Brilliant black BN)
05-BAG-C102
ALLERGEN MIXES
Allergen Mix
Food Mix (Egg white, Egg yolk, Milk, Codfish, Wheat, Peanut, Soybean, Hazelnut, Shrimp)
05-BAG-FX1
ALLERGEN MIXES
Allergen Mix
Inhalant Mix (6-grass mix, Cultivated rye grass, Common birch, Hazel, Mugwort, Ribwort/ Plantain, Alternaria tenuis, D. pteronissinus, D. farinae, Cat epithelium, Dog epithelium)
05-BAG-IX1
ALLERGEN MIXES
Allergen Mix
Neuromuscular Blockers Mix (Atracurium, Cisatracurium, Mivacurium, Pancurium, Propofol, Rocuronium, Suxamethonium, Vecuronium)
05-BAG2-CNBX
ALLERGEN MIXES
Allergen Mix
Ragweed Mix (Common and Giant ragweed)
05-BAG-WX1
ALLERGEN MIXES
Allergen Mix
Storage Mite Mix (Acarus Siro, Lepidoglyphus destructor, Tryophagus putrescentia, Glycyphagus domesticus)
05-BAG-DX1
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
19
Bone Metabolism
20
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Bone Metabolism Bone metabolism is a continual, cyclic interplay of bone growth and resorption that is carefully orchestrated by the dynamic relationship between osteoclasts, osteoblasts and an array of hormonal and regulatory influences. The relative levels of these signaling molecules dictate whether healthy, balanced bone metabolism ensues. Disturbances to this delicate equilibrium, where reabsorption is greater than growth, can weaken the skeletal architecture and put one at risk for the development of chronic 21
and debilitating diseases such as osteoporosis.
As we continue to gain a better understanding of the intricacies of bone metabolism and the key regulators involved, we may also gain further insights into the underlying mechanisms of bone-related diseases such as: • Osteopetrosis
• Cancer & Bone Metastases
• Paget’s Disease
• Immobilization-induced
• Rheumatoid Arthritis
bone loss
• Chronic Kidney Disease
Bone Metabolism Sclerostin
Mouse Sclerostin ELISA
Sclerostin, a protein product of the SOST gene, inhibits
ALPCO has developed a novel mouse sclerostin
osteoblast activity via antagonism of the Wnt signaling
immunoassay and confirmed its specificity through
pathway and plays a key role in the regulation of bone
validation via testing in a sclerostin knock out mouse.
formation. Reports show that sclerostin expression
This assay is a highly sensitive ELISA utilizing a polyclonal
and/or circulating levels are elevated in osteoporosis,
antibody based sandwich format for detecting low
immobilization-induced bone loss, rheumatoid
circulating levels of sclerostin in mouse samples. It
arthritis, multiple myeloma and bone metastases,
requires a small volume of serum or heparin plasma, which
making it a therapeutic target of great interest for
facilitates time-course sampling and/or the measurement
the fields of bone and cancer research.1,2,3 There are
of multiple biomarkers with one collection.
indications that sclerostin levels are also elevated with 22
chronic kidney disease, suggesting relevance in the study of renal insufficiency. 4,5
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
30-2112
5.1–200 pg/mL
4.8 pg/mL
500 µL
Plasma, Serum
Overnight
30-KM1100
See Protocol
See Protocol
500 µL
Plasma, Serum
1h 8m
25-OH Vitamin D ELISA
30-2109
2–300 nmol/L
2 nmol/L
30 µL
Serum
Overnight
25-OH Vitamin D HPLC
30-3400
4–1,250 nmol/L
4 nmol/L
500 µL
Plasma, Serum
See Protocol
Anti-TNF α Inhibitor ELISA (Antibody Against ENBREL®)
30-9653
Cut-off: See Protocol
See Protocol
100 µL
Serum
Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652
Cut-off: See Protocol
See Protocol
100 µL
EDTA Plasma, Serum
Overnight
Bone Sialoprotein ELISA
30-4222
3.1–50 ng/mL
1 ng/mL
100 µL
Serum
3h
Calcitonin ELISA
21-CALHU-E01 *
10–1,000 pg/mL
1 pg/mL
100 µL
Serum
4h 30m
Calcitonin Mouse/Rat IRMA
31-CALRT-R100
12–1,800 pg/mL
0.6 pg/mL
200 µL
Cell Culture, Plasma, Serum
Overnight
04-BI-20432
11–300 pmol/L
1.1 pmol/L
50 µL
Cell Culture, Serum
Overnight
1,25 (OH)2 Vitamin D ELISA 1,25 (OH)2 Vitamin D Immunotube Extraction Kit
Cathepsin K ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Human Sclerostin ELISA The Human Sclerostin ELISA is a highly referenced kit as
1 Rey JP, Ellies DL. Wnt modulators in the biotech pipeline. Developmental
a regulatory marker of bone turnover, requiring only a 20
Dynamics. Mar 2010; Vol 239 No 3: 102-114.
µL sample of human plasma or serum. The measurement
2 Gaudio et al. Increased sclerostin serum levels associated with bone
of circulating sclerostin in conjunction with other
formation and resorption markers in patients with immobilization-induced
biomarkers of bone turnover is becoming increasingly
bone loss. J Clin Endocrinol Metabolism. May 2010; Vol 95 No 5: 2248-
common in the study of bone disorders.
2253. 3 Colucci S et al. Myeloma cells suppress osteoblasts through sclerostin secretion. Blood Cancer. Jun 2011; Vol 1 No 6: e27. 4 Drüeke TB & Lafage-Proust. Sclerostin: just one more player in renal bone disease? Clin J Am Soc Nephrology. Apr 2011; Vol 6, No 4: 700-703. 5 Cejka D et al. Sclerostin and Dickkopf-1 in renal osteodystrophy. Clin J Am Soc Nephrology. Apr 2011; Vol 6 No 4: 877-882.
View sclerostin assays 04-BI-20492 on page 24, and 41-SCLMS-E01 on page 25
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
20-CTGHU-E01
1–500 ng/mL
3.24 ng/mL
25 µL
Serum
3h 45m
DKK-1 ELISA
04-BI-20412
3.125–50 pmol/L
0.38 pmol/L
15 µL
Serum
Overnight
DPD ELISA (Urine)
55-DE8007 *
3–300 nmol/L
1.1 nmol/L
50 µL
Urine
3h
43-FETHU-E01 *
0.5–3.7 ng/mL
5 ng/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h
43-FETHUU-E01 *
0.01–1.30 g/L
40 ng/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture
2h 45m
13-COMP-200
10–80 ng/mL
10 ng/mL
5 µL
Serum
Overnight
30-3201
7.3–2,500 pmol/mL
7.3 pmol/mL
500 µL
Urine
See Protocol
IL-6 ELISA
45-IL6HU-E01
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA
45-IL6HU-E05
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
CTGF ELISA
Fetuin-A ELISA
Fetuin-A Ultrasensitive ELISA hCOMP ELISA Hydroxy Pyridinium Crosslinks HPLC Assay (PYD/DPD)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
23
Bone Metabolism Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
IL-6 Monkey ELISA
61-IL6MK-E01
1.9–120 U/mL
1.3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-6 Mouse ELISA
61-IL6MS-E01
31.3–2,000 pg/mL
6.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
61-IL6RT-E01
31–2,000 pg/mL
12 pg/mL
50 µL
Cell Culture, Serum
3h 10m
31-IPTBO-E01
0–10,000 pg/mL
10 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h 30m
30-1012
0.27–195 ng/mL
0.27 ng/mL
30 µL
Plasma, Serum
5h
04-BI-20872
2–40 pmol/L
0.55 pmol/L
50 µL
Cell Culture, Plasma, Serum
4h 30m
Osteocalcin ELISA (1-43/49)
43-OSNHU-E01
0–64 ng/mL
0.31 ng/mL
25 µL
Serum
1h 20m
Osteocalcin Intact ELISA
38-OSTHU-E01
2–90 ng/mL
0.4 ng/mL
25 µL
Serum
2h 30m
Osteocalcin Mouse ELISA
31-OSTMS-E01
3.2–95 ng/mL
0.4 ng/mL
20 µL
Cell Culture, Plasma, Serum
3h
31-OSTRT-E01
0.3–35 ng/mL
0.05 ng/mL
20 µL
Cell Culture, Plasma, Serum
3h
72-OSTEO-CT-US
0–300 ng/mL
0.4 ng/mL
50 µL
EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Osteopontin ELISA
41-OPNHU-E01
0.31–20 ng/mL
0.05 ng/mL
10 µL
Heparin Plasma, Urine
3h
Osteopontin Mouse ELISA
41-OPNMS-E01
0.03–2.0 ng/mL
0.015 ng/mL
5 µL
Plasma
3h
04-BI-20403
25–400 pg/mL
1.4 pg/mL
20 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
5h 30m
30-1020
125–4,000 pg/mL
125 pg/mL
100 µL
Cell Culture, Plasma, Serum, Urine
Overnight
72-OCFK07-PIIIP
0.1–14 U/mL
0.1 U/mL
20 µL
Plasma, Serum
5h
31-BIPRT-E01
25–2,700 pg/mL
3 pg/mL
25 µL
Cell Culture, Plasma
3h 30m
31-IPTHUU-E01
3.2–143 pg/mL
0.3 pg/mL
150 µL
Cell Culture, EDTA Plasma, Plasma
3h 30m
PTH Intact ELISA (1-84)
21-IPTHU-E01 *
7–700 pg/mL
1.57 pg/mL
25 µL
Serum
3h 30m
PTH Intact Mouse ELISA (1-84)
31-PTHMS-E01
32–1,045 pg/mL or 336–2,616 pg/mL
4 pg/mL
20 µL
Cell Culture, Plasma
3h 30m
PTH Intact Porcine ELISA
31-IPTPO-E01
0–1,000 pg/mL
1 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h 30m
PTH Intact Rat ELISA (1-84)
31-IPTRT-E01
25–2,700 pg/mL
1.6 pg/mL
25 µL
Cell Culture, Plasma, Serum
3h 30m
04-BI-20492
15–240 pM
2.6 pM
20 µL
EDTA Plasma, Heparin Plasma, Serum
Overnight
IL-6 Rat ELISA Intact PTH Bovine ELISA Myostatin ELISA Nt-proCNP ELISA
24 Osteocalcin Rat ELISA
Osteocalcin RIA
Osteoprotegerin ELISA
Osteoprotegerin Mouse/Rat ELISA Procollagen III Peptide RIA PTH Bioactive Intact Rat ELISA PTH High Sensitive ELISA (1-34)
Sclerostin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
41-SCLMS-E01
37.5–1,200 pg/mL
17.4 pg/mL
15 µL
Heparin Plasma, Serum
5h 20m
sRANKL Mouse/Rat ELISA
30-1019
125–4,000 pg/mL
125 pg/mL
100 µL
Cell Culture, Serum, Urine
Overnight
sRANKL Total ELISA
30-1016
0–60 pg/mL
1.5 pg/mL
10 µL
Cell Culture, Plasma, Serum
Overnight
Vitamin D Binding Protein ELISA
30-2314
2.2–60 ng/mL
1.23 ng/mL
10 µL
Plasma, Serum, Urine
2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 30m
Vitamin D2/D3 HPLC
30-3420
4–1,250 nmol/L
4 nmol/L
500 µL
Plasma, Serum
See Protocol
Vitamin K1 HPLC
30-2400
See Protocol
0.15 ng/mL
1 mL
Plasma, Serum
See Protocol
Sclerostin Mouse ELISA
25
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
CVD & Oxidative Stress
26
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
CVD & Oxidative Stress Cardiovascular Disease (CVD) encompasses a constellation of diseases related to the heart and/or circulatory system. Despite efforts to understand and combat heartrelated disease, the first and fourth leading causes of death in the United States are coronary disease and ischemic stroke, respectively.1 This is striking, considering extensive campaigns to educate the public on diet and lifestyle factors that are, in many cases, controllable. Two primary risk factors for CVD include obesity and Type 27
2 Diabetes, both of which have continued to be on the rise over the past few decades. It is evident that regardless of the advancements in scientific knowledge of the disease and the improvements in diagnosis and treatment, more research is necessary to further our understanding of CVD.
The American Heart Association has dedicated $3.5 billion to the research of CVD and stroke since the late 1940’s,1 and it continues to fund a spectrum of research from community outreach to genomics. These efforts, combined with federal and philanthropic funding, facilitate the research required for the identification of novel biomarkers and testing their relevance in basic, preclinical and clinical research.
1
American Heart Association â&#x20AC;&#x201C; Research. 2013. <http://my.americanheart.org/professional/Research/Research_UCM_316889_SubHomePage.jsp>
CVD & Oxidative Stress Angiotensin Converting Enzyme Angiotensin Converting Enzyme (ACE) catalyzes the conversion of angiotensin I to angiotensin II and inactivates bradykinin during blood pressure regulation via the renin-angiotensin system. Measurement of ACE levels with ALPCO’s FDA registered assay has been shown to aid in the diagnosis and monitoring of conditions such as sarcoidosis, diabetic nephropathy and cardiovascular disease.1
1 Steven A. Atlas, MD. The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition. JMCP. Oct 2007; Vol 13 No 8.
28
View ACE assays 01-KK-ACK and 01-KK-ACF on page 29
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
60-DH4
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
60-DH104
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA (2 kits)
60-DH14
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA (5 kits)
60-DH24
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
60-DH1
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
See Protocol
14,15-DHET ELISA (10 kits)
60-DH101
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
14,15-DHET ELISA (2 kits)
60-DH11
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
14,15-DHET ELISA (5 kits)
60-DH21
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA
60-20H1
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA (2 kits)
60-20H11
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA (5 kits)
60-20H21
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA
11,12-DHET ELISA (10 kits)
14,15-DHET ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
ANP (Atrial Natriuretic Peptide)
BNP (Brain-derived Natriuretic
ALPCO offers several assays for the
is released into circulation from
Peptide) is expressed in the
direct measurement of natriuretic
atrial myocytes in response to fiber
ventricular myocardium and
peptides using small sample volumes
contraction and elevated levels can be
released with contraction. Elevated
which do not require extraction.
predictive of cardiac dysfunction.1,2
levels of BNP can be predictive of heart failure.1,2
1 Hoffmann U et al. Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients. Clin Lab. 2005; Vol 51: 373-379. 2 Ellinor PT, et al. Discordant atrial natriuretic peptide and brain natriuretic peptide levels in lone atrial fibrillation. J Am Coll Cardiology. Jan 2005; Vol 45 No 1: 82-86.
View ANP assays 32-5103, 13-BANI 1 and BNP assay 04-BI-20852W on page 30
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
60-8ISO1
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
See Protocol
8-isoPGF2a ELISA (10 kits)
60-8ISO101
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
Overnight
8-isoPGF2a ELISA (2 kits)
60-8ISO11
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
8-isoPGF2a ELISA (5 kits)
60-8ISO21
See Protocol
10 pg/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
See Protocol
ACE Kinetic
01-KK-ACK * ^
3–150 ACE units
5 ACE Units
25 µL
Serum
15m
ACE Kinetic
01-KK-ACK2 * ^
3–150 ACE Units
5 ACE Units
25 µL
Serum
15m
ACE Kinetic High Sensitive
01-KK-ACF
1–30 U/L
1 U/L
80 µL
Cerebrospinal Fluid
See Protocol
ACE Kinetic Jumbo (1200)
01-KK-ACKX * ^
3–150 ACE units
5 ACE Units
25 µL
Serum
15m
AcSDKP ELISA (N-acetylSer-Asp-Lys-Pro)
32-5881
0.19–25 nM
0.19 nM
150 µL
Plasma, Serum, Urine
Overnight
21-ACTHU-E01 *
5–500 pg/mL
0.46 pg/mL
200 µL
Plasma
5h
Adenosine HPLC
30-8000
0.78–6.84 µM
0.78 µM
500 µL
Urine
1h 30m
ADMA ELISA
30-7828
0.1–2 µmol/L
0.05 µmol/L
50 µL
Citrate Plasma, EDTA Plasma, Plasma, Serum
Overnight
ADMA Mouse/Rat ELISA
30-3001
0.1–3 µmol/L
0.05 µmol/L
100 µL
EDTA Plasma, Serum
Overnight
8-isoPGF2a ELISA
ACTH ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
29
CVD & Oxidative Stress ADMA (Asymmetric
ADMA
found in blood plasma where
NO=Endogenous anti-arteriosclerotic molecule:
inhibits
Dimethylarginine) is a protein
has vasodilatory effects
NO-Synthase L-Arginine
elevated levels inhibit synthesis
inhibits monocyte adhesion
L-Citrullin +
NO
inhibits smooth muscle cell proliferation inhibits platelet aggregation
of nitric oxide thus resulting in vasoconstriction and increased blood pressure.1,2 The ADMA Xpress ELISA allows for quantitative measurement in human samples with results in less than four hours.
1 Bouras G et al. Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular disease? Curr Top Med Chem. 2013; Vol 13 No 2: 180-200. 2 Böger RH et al. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation. Nov 1998; Vol 98 No 18:1842-1847.
30
View the ADMA Xpress assay 30-7860 on page 30
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
ADMA Xpress ELISA
30-7860
0.1 µM–2 µM
0.1 µM
25 µL
EDTA Plasma, Serum
3h
Angiotensin II ELISA
32-5880
1–125 pg/mL
1 pg/mL
100 µL
Plasma
Overnight
01-RK-A22 *
2–500 pg/mL
1 pg/mL
1 mL
Plasma
Overnight
32-5103
15.6–2,000 pg/mL
15.6 pg/mL
50 µL
Citrate Plasma, EDTA Plasma
Overnight
13-BANI 1
7.8–1,000 pg/mL
3.5 pg/mL
500 µL
Plasma
Overnight
13-GCP-100 *
See Protocol
Cut-off: See Protocol
25 µL
Serum
30m
30-5200
130–393 µmol/L
130 µmol/L
20 µL
Plasma, Serum
15m
41-AT3RT-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Serum
1h 40m
AOPP Colorimetric Assay
30-7811w
6.25–100 µmol/L
1.5 µmol/L
40 µL
EDTA Plasma, Plasma
30m
AOPP Colorimetric Assay (Cuvette)
30-7811c
6.25–100 µmol/L
1.1 µmol/L
400 µL
EDTA Plasma, Plasma
30m
41-APOHU-E01
15.6–500 ng/mL
15.6 ng/mL
100 µL
Plasma, Serum
1h 40m
04-BI-20852W
5–1,000 fmol/mL
5 fmol/mL
35 µL
Cell Culture, Plasma, Serum
Overnight
48-BRAHU-E01
7.2–5,000 pg/well
7.2 pg/mL
10 µL
Plasma, Urine
Overnight
Angiotensin II RIA ANP Rat ELISA ANP RIA Anti-GBM & ANCA Rapid Screen ELISA Antioxidative Capacity ELISA Antithrombin III Rat ELISA
Apolipoprotein A1 ELISA BNP Fragment ELISA (Nt-proBNP 8-29) Bradykinin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Sample Size
Sample Type
Incubation
156.25 pmol/mL
4 µL
Biological Fluids, Bronchial Lavage, Cell Culture, Cerebrospinal Fluid, Plasma
4h
18.75–600 ng/mL
18.75 ng/mL
5 µL
Serum
2h 10m
47-CETHU-E01
0.2–5 µg/mL
0.2 µg/mL
10 µL
Plasma, Serum
3h 15m
25-CKMHU-E01
7.5–200 ng/mL
7.5 ng/mL
20 µL
Serum
1h 20m
CRF-HS Mouse/Rat ELISA
48-CRFMS-E01
0.078–2.5 ng/mL
0.078 ng/mL
50 µL
Plasma, Tissue Culture
8h 30m
CRP Canine ELISA
41-CRPCA-E01
2.125–200 ng/mL
5 ng/mL
5 µL
Plasma, Serum
25m
30-9710s
1.9–150 ng/mL
0.124 ng/mL
10 µL
Plasma, Serum, Stool, Urine
2h 15m
CRP Equine ELISA
41-CRPEQ-E01
10–320 ng/mL
10 ng/mL
5 µL
Plasma, Serum
1h 15m
CRP Feline ELISA
41-CRPFE-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 15m
CRP Mouse ELISA
41-CRPMS-E01
0.39–25 ng/mL
0.39 ng/mL
5 µL
Plasma, Serum
25m
CRP Rabbit ELISA
41-CRPRB-E01
6.25–200 ng/mL
5 ng/mL
2 µL
Plasma, Serum
25m
CRP Rat ELISA
41-CRPRT-E01
6.25–200 ng/mL
5 ng/mL
5 µL
Plasma, Serum
25m
30-8220
2.1–80 U/mL
0.2 U/mL
100 µL
Plasma, Serum
2h 30m
04-BI-20742
0–80 nmol/L
0.2 nmol/L
10 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
04-BI-20082H
0–3 pmol/IL
0.02 pmol/IL
50 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
5h 30m
04-BI-20052
0.02–10 fmol/mL
0.02 fmol/mL
50 µL
Cell Culture, Plasma, Saliva, Serum, Urine
Overnight
Erythropoietin ELISA
21-EPOHU-E01 *
3–500 mIU/mL
0.6 mIU/mL
400 µL
Serum
2h 30m
Ferritin ELISA
25-FERHU-E01 *
15–1,000 ng/mL
5 ng/mL
20 µL
Serum
1h 5m
41-FERMS-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Serum
1h 20m
41-FERRT-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Biological Fluids
1h 20m
43-FETHU-E01 *
0.5–3.7 ng/mL
5 ng/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h
43-FETHUU-E01 *
0.01–1.30 g/L
40 ng/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture
2h 45m
41-FIBCA-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Carbonylated Protein ELISA
Ceruloplasmin Rat ELISA CETP ELISA Creatine Kinase ELISA
CRP ELISA
DAO REA
Endostatin ELISA
Endothelin Big ELISA
Endothelin ELISA (1-21)
Ferritin Mouse ELISA Ferritin Rat ELISA
Fetuin-A ELISA
Fetuin-A Ultrasensitive ELISA Fibrinogen Canine ELISA
Catalog #
Range
Sensitivity
30-7822
156.25–2,500 pmol/mL
41-CERRT-E01
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
31
CVD & Oxidative Stress Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Fibrinogen ELISA
41-FIBHU-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Biological Fluids, Plasma, Serum
1h 40m
Fibrinogen Mouse ELISA
41-FIBMS-E01
25–800 ng/mL
25 ng/mL
5 µL
Citrate Plasma, Plasma, Serum
1h 40m
Fibrinogen Porcine ELISA
41-FIBPO-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 15m
Fibrinogen Rat ELISA
41-FIBRT-E01
25–800 ng/mL
25 ng/mL
5 µL
Citrate Plasma, Plasma, Serum
1h 40m
61-FIBHU-E01
0.31–20 ng/mL
0.1 ng/mL
50 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
41-FNEMS-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 40m
41-FNERT-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 40m
61-GALHU-E01
0.39–25 ng/mL
0.12 ng/mL
50 µL
Cell Culture, EDTA Plasma, Serum
3h 10m
Glutathione HPLC (GSH/GSSG)
30-1800
620–970 µmol/L
6 µmol/L
100 µL
EDTA Plasma, Plasma
See Protocol
GPx Activity Assay
30-7031
70 mg/mL
See Protocol
20 µL
Biological Fluids
1h
GST Activity Assay
30-2631
See Protocol
See Protocol
100 µL
Biological Fluids
1h
GST-pi ELISA
30-7960
9.4–600 ng/mL
9 ng/mL
25 µL
Serum, Tissue Culture
Overnight
Haptoglobin Bovine ELISA
41-HAPBO-E01
15.6–1,000 ng/mL
15.6 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin Canine ELISA
41-HAPCA-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin ELISA
41-HAPHU-E01
3.125–200 ng/mL
3.125 ng/mL
100 µL
Plasma, Serum
35m
Haptoglobin Equine ELISA
41-HAPEQ-E01
18.75–600 ng/mL
18.75 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Feline ELISA
41-HAPFE-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Mouse ELISA
41-HAPMS-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
Haptoglobin Porcine ELISA
41-HAPPO-E01
25–400 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin Rabbit ELISA
41-HAPRB-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
Haptoglobin Rat ELISA
41-HAPRT-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
30-7816A
3.3–100 ng/mL
1.8 ng/mL
100 mg
Stool
2h 20m
Hemoglobin Equine ELISA
41-HEMEQ-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h
Hemoglobin Mouse ELISA
41-HEMMS-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 40m
Hemoglobin Rat ELISA
48-HEMRT-E01
5–160 ng/mL
5 ng/mL
100 µL
Urine
3h
Hemoglobin Rat ELISA
41-HEMRT-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
Fibronectin ELISA
Fibronectin Mouse ELISA Fibronectin Rat ELISA Galectin-3 ELISA
32
Hemoglobin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Hemopexin ELISA
41-HMPHU-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Serum
1h 10m
Hemopexin Mouse ELISA
41-HMPMS-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Serum
1h 30m
41-HMPRT-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Serum
1h 20m
Hepcidin 25 LC-MS
30-KM4000
See Protocol
1 ng/mL
See Protocol
Serum
See Protocol
Hepcidin ELISA (25 C-Terminal)
20-HCTHU-E01
2–80 ng/mL
2 ng/mL
20 µL
Plasma, Serum
1h 50m
Hepcidin Prohormone ELISA
20-HEPHU-E01
10–1,000 ng/mL
4 ng/mL
50 µL
Serum, Urine
3h 30m
Homocysteine ELISA
66-HCYHU-E01
2–50 µmol/L
1 µmol/L
25 µL
EDTA Plasma, Serum
See Protocol
Homocysteine HPLC
30-2801
See Protocol
0.6 mol/L
50 µL
Plasma
1h 50m
Krytopyrrole Colorimetric Assay
30-7823
100–1,500 ng/mL
100 ng/mL
1 mL
Urine
2h
LCAT ELISA
47-LCAHU-E01
0.14–35 µg/mL
0.14 µg/mL
10 µL
Plasma, Serum
3h 15m
Lipoprotein (a) ELISA
55-LPAHU-E01
10–70 mg/dL
< 5 mg/dL
5 µL
Plasma, Serum
2h 30m
LPL ELISA
47-LPLHU-E01
9–500 ng/mL
9 ng/mL
50 µL
Plasma, Serum
4h 15m
Malondialdehyde HPLC
30-1900
See Protocol
0.15 nmol/L
20 µL
Plasma, Serum, Urine
1h
MPO ELISA
30-6630
1.2–100 ng/mL
1.6 ng/mL
100 mg
Stool, Urine
2h 20m
MPO ELISA (Serum and Plasma)
30-6631A
1.9–30 ng/mL
1.08 ng/mL
10 µL
Plasma, Serum
3h 20m
MPO Mouse ELISA
41-MPOMS-E01
0.31–20 ng/mL
0.31 ng/mL
5 µL
Plasma, Serum
1h 30m
MRP 8/14 ELISA
01-EK-MRP8/14
0.4–24 µg/mL
0.4 µg/mL
10 µL
Plasma, Serum
1h 15m
Myoglobin ELISA
25-MYOHU-E01 *
25–1,000 ng/mL
25 ng/mL
20 µL
Serum
1h 5m
Myoglobin ELISA
24-MYOHU-E01
0–250 ng/mL
6.25 ng/mL
10 µL
Serum, Urine
30m
Myoglobin Mouse ELISA
41-MYOMS-E01
4.69–300 ng/mL
4.69 ng/mL
30 µL
Plasma, Serum
1h 40m
41-MYORT-E01
3.125–200 ng/mL
3.125 ng/mL
75 µL
Serum
1h 25m
30-7824
32–1,250 nM
34.1 nM
100 mg
Plasma, Serum, Stool
4h
48-NOSHU-E01
0.133–32.4 nM
0.133 nM
50 µL
Tissue Culture
Overnight
Nt-proCNP ELISA
04-BI-20872
2–40 pmol/L
0.55 pmol/L
50 µL
Cell Culture, Plasma, Serum
4h 30m
Osteoprotegerin ELISA
04-BI-20403
25–400 pg/mL
1.4 pg/mL
20 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
5h 30m
30-1020
125–4,000 pg/mL
125 pg/mL
100 µL
Cell Culture, Plasma, Serum, Urine
Overnight
Hemopexin Rat ELISA
Myoglobin Rat ELISA Nitrotyrosine ELISA NOS1 ELISA
Osteoprotegerin Mouse/Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
33
CVD & Oxidative Stress Renin Renin is a constituent of the Renin-Angiotensin-Aldosterone System (RASS) which controls blood pressure, renal blood flux, glomerular filtration, and sodium/potassium homeostasis.1,2 Plasma renin is a reliable index for the activity of the RAAS. In cases of dysfunction, renin testing with ALPCO’s FDA registered Active Renin RIA can aid in detection of renin producing tumors, monitoring of glucocorticoid therapy and antihypertensive treatments and contribute to the diagnosis of hypertension, hyperaldosteronism, and mineral corticoid deficiency.
1 Basso N, Terragno NA. History about the discovery of the renin-angiotensin system. Hypertension. Dec 2001. Vol 38 No 6: 1246–1249. 2 Chappell MC. Nonclassical Renin-Angiotensin system and renal function. Compr Physiology. Oct 2012; Vol 2 No 4: 2733-2752.
34
View renin assays 11-RENHU-E02 on page 34, and 20-RENHU-E01 and 11-RENHU-L02 on page 35
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Oxidized LDL Antibody ELISA
04-BI-20032
37–1,200 mU/mL
27 mU/mL
50 µL
Serum
2h 20m
30-7810
9–250 ng/mL
9 ng/mL
10 µL
EDTA Plasma, Plasma, Serum
2h 20m
04-BI-5007
Cut-off: See Protocol
7 µmol/L
10 µL
Plasma, Serum
15m
48-PLAHU-R50
100–10,000 ng/dL
100 ng/dL
50 µL
Plasma, Serum
2h 30m
Plasminogen Canine ELISA
41-PLACA-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 45m
Plasminogen ELISA
41-PLAHU-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Serum
2h 5m
Plasminogen Mouse ELISA
41-PLAMS-E01
6.25–1,900 ng/mL
6.25 ng/mL
5 µL
Serum
1h 30m
Plasminogen Porcine ELISA
41-PLAPO-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Plasminogen Rabbit ELISA
41-PLARB-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
Plasminogen Rat ELISA
41-PLART-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 30m
04-BI-20892
0.63–10 nmol/L
0.05 nmol/L
10 µL
Cell Culture, Plasma, Urine
4h
72-RENINE *
0–320 pg/mL
1 pg/mL
300 mL
Plasma
3h
11-RENHU-E02
0.2–60 ng/mL
0.038 ng/mL
50 µL
EDTA Plasma, Plasma
1h 45m
Oxidized LDL ELISA
OxyStat ELISA
Phospholipase 2 RIA
proANP ELISA (1-98) Renin Active RIA Renin Activity ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Renin Activity LIA
11-RENHU-L02
0.2–25 ng/mL
0.08 ng/mL
500 µL
EDTA Plasma, Plasma
1h 30m
Renin ELISA
20-RENHU-E01
0.81–28 pg/mL
0.81 pg/mL
50 µL
EDTA Plasma
3h 15m
Serum Amyloid A ELISA
41-SAAHU-E01
0.157–10 ng/mL
0.157 ng/mL
10 µL
Plasma, Serum
1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E01
31.25–2,000 ng/mL
31.25 ng/mL
5 µL
Serum
1h 40m
t-PA ELISA
61-TPAHU-E01
15.6–1,000 pg/mL
6 pg/mL
10 µL
Cell Culture, Serum
2h 10m
Transferrin Canine ELISA
41-TRACA-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Transferrin ELISA
41-TRAHU-E01
9.375–600 ng/mL
9.375 ng/mL
5 µL
Plasma, Serum
1h 15m
Transferrin Mouse ELISA
41-TRAMS-E01
1.56–100 ng/mL
1.56 ng/mL
5 µL
Plasma, Serum
1h 10m
Transferrin Rabbit ELISA
41-TRARB-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 30m
Transferrin Rat ELISA
41-TRART-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Biological Fluids
40m
Troponin I ELISA
25-TR1HU-E01
1.5–75 ng/mL
1 ng/mL
100 µL
Serum
1h 50m
30-KC-1700
See Protocol
0.02 µg/mL
200 µL
Plasma, Serum, Whole Blood
15m
30-1013
32–20,000 pg/mL
32 pg/mL
150 µL
Cell Culture, Plasma, Serum
4h 10m
01-RK-VPD ^
1.25–80 pg/mL
0.75 pg/mL
1 mL
EDTA Plasma
Overnight
01-RK-AR1
0.63–80 pg/mL
0.4 pg/mL
1 mL
EDTA Plasma, Urine
Overnight
30-1600
See Protocol
0.05 mg/mL
100 µL
EDTA Plasma, Serum
See Protocol
Vitamin B6 Enzymatic Assay
01-KK-VB6
9–250 nM
7 nM
25 µL
EDTA Plasma
45m
Vitamin B6 HPLC
30-2100
4.3–17.9 ng/mL
0.2 ng/mL
200 µL
EDTA Plasma, Plasma, Serum
See Protocol
Ubiquinone Coenzyme Q10 HPLC Kit Urotensin II ELISA Vasopressin Direct RIA (ADH/AVP) Vasopressin Ultrasensitive RIA (ADH/AVP) Vitamin A and Vitamin E HPLC Assay (Retinol and Tocopherol HPLC Assay)
*
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
35
Diabetes & Obesity
36
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Diabetes & Obesity According to the 2011 National Diabetes Fact Sheet, diabetes affects 8.3% of the U.S. population. It is the leading cause of kidney failure, nontraumatic lower-limb amputations and new cases of blindness among adults and is a major cause of heart disease and stroke.1 Globally, diabetes affects 347 million people, with Type 2 diabetes accounting for approximately 90% of all diagnosed cases2 and is projected to be the 7th leading cause of death in 2030.3 Additionally, obesity is a major risk factor for Type 37
2 diabetes, and having excess visceral, or abdominal, fat is associated with more than a twofold-increased risk of developing diabetes.4
With no cure for Type 1 or Type 2 diabetes, and a lack
to researchers in the Diabetes & Obesity field and will
of effective obesity treatments, investigators are
continue to support their efforts in gaining a greater
continually in need of new methods to advance their
understanding of these conditions.
research. ALPCO has been a leader in offering solutions
1
Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2011.
2
World Health Organization. Diabetes Fact sheet N째312. Geneva, World Health Organization, 2013.
3
Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011.
4
de Lemos JA, et al. Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA. Sep 2012; Vol 308 No 11: 1150-1159.
Diabetes & Obesity Energy Homeostasis
STELLUX™ Chemiluminescence
Energy homeostasis is a well-regulated process
Our commitment to support innovation in the Diabetes
that depends on the coordination between feeding
and Obesity field has allowed us numerous opportunities
behavior and energy expenditure. The control of energy
to respond to the changing demands in the market.
homeostasis in humans has received much attention in
ALPCO’s STELLUX™ chemiluminescent detection system
recent years due to alterations caused by the onset of
is a result of that commitment.
conditions such as obesity and diabetes. STELLUX™ is a glow-based chemiluminescent
38
ALPCO offers numerous Research Use Only and
reaction that delivers rapid and sensitive detection of
IVD assay kits to assist both academic and industry
analytes, broad dynamic ranges and shorter run times
researchers with quantification of analytes associated
compared to colorimetric ELISA systems. STELLUX™
with energy homeostasis. It is now recognized that there
chemiluminescence immunoassays will prove to set new
are many central and peripheral factors involved in
standards in the field of diabetes and obesity research.
energy homeostasis; understanding of these mechanisms should lead to effective treatments for the control of diabetes, obesity and other metabolic disorders.
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
72-AAI
See Protocol
See Protocol
50 µL
Plasma, Serum
2h 30m
32-5106
1.95–250 pg/mL
0.8 pg/mL
100 µL
Plasma
3h
Adiponectin HMW & Total ELISA
47-ADPHU-E01
0.075–4.8 ng/mL
0.019 ng/mL
10 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
3h
Adiponectin HMW & Total Mouse ELISA
47-ADPMS-E01
0.125–8 ng/mL
0.032 ng/mL
5 µL
EDTA Plasma, Plasma, Serum
3h
Adiponectin Rat ELISA
22-ADPRT-E01
0.25–10 ng/mL
0.08 ng/mL
5 µL
Plasma, Serum
2h 30m
47-ADPHUT-E01
0.075–4.8 ng/mL
0.019 ng/mL
10 µL
EDTA Plasma, Heparin Plasma, Serum
2h 40m
32-5181
0.5–25 ng/mL
0.1 ng/mL
20 µL
Cell Culture, Plasma, Serum
2h 30m
AAI RIA Acylated Ghrelin ELISA
Adiponectin Total ELISA
AFABP ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
41-ALBCA-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 45m
30-6330
12.5–800 µg/L
12.5 µg/L
100 mg, 10 µL
Stool, Urine
2h 20m
Albumin Monkey ELISA
41-ALBMK-E01
12.5–400 ng/mL
12.5 ng/mL
100 µL
Serum, Tissue Culture
1h 40m
Albumin Mouse ELISA
41-ALBMS-E01
7.8–500 ng/mL
5 ng/mL
2 µL
Plasma, Serum, Urine
1h 10m
Albumin Porcine ELISA
41-ALBPO-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum, Urine
1h 40m
Albumin Rat ELISA
41-ALBRT-E01
6.25–400 ng/mL
5 ng/mL
5 µL
Plasma, Serum, Urine
1h 10m
35-INAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
13-CCKHU-R100
0.78–25 pmol/L
0.3 pmol/L
1 mL
Plasma
Overnight
80-CPTHU-E01.1 *
20–3,000 pmol/L
2.95 pmol/L
25 µL
Plasma, Serum
2h
80-CPTHU-E10 *
20–3,000 pmol/L
2.95 pmol/L
25 µL
Plasma, Serum
2h
C-peptide ELISA Mouse Jumbo
80-CPTMS-E10
60–3,000 pM
7.6 pM
10 µL
Serum
2h 15m
C-Peptide IRMA
72-C-Peptide
See Protocol
0.036 ng/mL
50 µL
Plasma, Serum, Urine
2h
80-CPTMS-E01
60–3,000 pM
7.6 pM
10 µL
Serum
2h 15m
C-peptide Rat ELISA
80-CPTRT-E01
50–4,500 pM
10.8 pM
10 µL
Serum
2h 15m
FGF-21 ELISA
62-FGFHU-E01
30–1,920 pg/mL
10.4 pg/mL
100 µL
Cell Culture, Plasma, Serum
2h 35m
FGF-21 Mouse ELISA
62-FGFMS-E01
31.2–2,000 pg/mL
10.1 pg/mL
100 µL
Cell Culture, Plasma, Serum
2h 35m
GAD ELISA
21-GADHU-E01
0.6–2.99 U/mL
See Protocol
10 µL
Serum
2h 30m
Gastrin RIA
13-MD 302 *
15.6–500 pmol/L
5 pmol/L
100 µL
Serum
1h 45m
Gastrin RIA
72-GASK-PR
0–500 μU/mL
10 μU/mL
100 µL
Plasma, Serum
3h
Ghrelin Acylated Mouse/Rat ELISA
32-5117
1.95–250 pg/mL
0.7 pg/mL
100 µL
Plasma
3h
Ghrelin NonAcylated ELISA
32-5119
1.95–250 pg/mL
0.6 pg/mL
10 µL
EDTA Plasma
3h
Ghrelin Non-Acylated Mouse/Rat ELISA
32-5118
1.95–250 pg/mL
0.8 pg/mL
10 µL
EDTA Plasma
3h
22-GHR-R90
200–6,400 pg/mL
40 pg/mL
100 µL
Plasma, Serum
Overnight
48-GLIRT-E01
0.206–50 pmol/mL
0.206 pmol/mL
30 µL
Plasma
Overnight
GLP-1 Active ELISA (7-36)
43-GP1HU-E01
0.64–48 pmol/L
0.05 pmol/L
100 µL
EDTA Plasma, Plasma
Overnight
GLP-1 Total ELISA (7-36 and 9-36)
43-GPTHU-E01
1.8–54.5 pmol/L
0.6 pmol/L
100 µL
EDTA Plasma, Plasma
Overnight
Albumin Canine ELISA Albumin ELISA
Anti-Insulin IgG ELISA CCK RIA C-Peptide ELISA C-Peptide ELISA Jumbo
C-peptide Mouse ELISA
Ghrelin Total RIA
Glicentin Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
39
Diabetes & Obesity Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
48-GP2HU-E01.1
0.412–100 ng/mL
0.412 ng/mL
25 µL
Plasma, Serum
Overnight
48-GP2MS-E01
0.412–100 ng/mL
0.412 ng/mL
25 µL
Plasma, Serum
Overnight
GLP-2 Rat ELISA
48-GP2RT-E01
0.137–100 ng/mL
0.137 ng/mL
25 µL
Plasma, Serum
Overnight
Glucagon ELISA
48-GLUHU-E01
50–10,000 pg/mL
50 pg/mL
50 µL
Plasma
Overnight
13-GLUHU-R100 *
4.7–150 pmol/L
3 pmol/L
200 µL
Plasma
Overnight
30-1800
620–970 µmol/L
6 µmol/L
100 µL
EDTA Plasma, Plasma
See Protocol
61-I1BRT-E01
31.3–2,000 pg/mL
4 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-6 ELISA
45-IL6HU-E01
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA
45-IL6HU-E05
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
IL-6 Monkey ELISA
61-IL6MK-E01
1.9–120 U/mL
1.3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-6 Mouse ELISA
61-IL6MS-E01
31.3–2,000 pg/mL
6.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
61-IL6RT-E01
31–2,000 pg/mL
12 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-8 ELISA
61-IL8HU-E01
15.6–1,000 pg/mL
2 pg/mL
50 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-8 Monkey ELISA
61-IL8MK-E01
19.5–1,250 U/mL
3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-8 Porcine ELISA
45-IL8PO-E01
31.2–2,000 pg/mL
10 pg/mL
50 µL
Cell Culture, Serum
4h
45-IL8HUU-E01
0.39–25 pg/mL
0.1 pg/mL
100 µL
Cell Culture, Plasma, Serum, Urine
4h
Insulin Autoantibody ELISA
21-IAAHU-E01
Cut-off: See Protocol
See Protocol
25 µL
Serum
Overnight
Insulin Bovine ELISA
80-INSBO-E01
0.15–6 ng/mL
0.10 ng/mL
25 µL
Plasma, Serum
2h 15m
Insulin ELISA
80-INSHU-E01.1 *
3–200 µIU/mL
0.399 µIU/mL
25 µL
Plasma, Serum
2h
Insulin ELISA Jumbo
80-INSHU-E10.1 *
3–200 µIU/mL
0.399 µIU/mL
25 µL
Plasma, Serum
2h
Insulin High Range Mouse ELISA
80-INSMSH-E01
3–150 ng/mL
1.99 ng/mL
5 µL
Plasma, Serum
2h 15m
Insulin High Range Mouse ELISA Jumbo
80-INSMSH-E10
3–150 ng/mL
1.99 ng/mL
5 µL
Plasma, Serum
2h 15m
Insulin High Range Rat ELISA
80-INSRTH-E01
3–150 ng/mL
0.52 ng/mL
5 µL
Plasma, Serum
2h
GLP-2 ELISA
GLP-2 Mouse ELISA
Glucagon RIA Glutathione HPLC (GSH/GSSG) IL-1ß Rat ELISA
40
IL-6 Rat ELISA
IL-8 Ultrasensitive ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Glucagon Glucagon is the counter-regulatory hormone to insulin
agonists, DPP-4 inhibitors) have been shown to suppress
and is secreted from pancreatic alpha-cells in response
glucagon secretion from the alpha-cells, attributing to the
to low blood glucose. Hyperglucagonemia has been
glucose-lowering effect of these treatments.1 As such, the
implicated in the pathophysiology of Type 2 Diabetes
inhibition of glucagon may prove to be a viable target for
Mellitus. Incretin-based treatments (GLP-1 receptor
new drug therapies.
1 Morten Hansen, Kristine J. Hare, Jens J. Holst and Filip K. Knop. Inhibition of Glucagon Secretion by GLP-1 Agonists and DPP4 Inhibitors JCMD. Jun 2011; Vol 2 No 1: 7-13.
View glucagon assays 48-GLUHU-E01 and 13-GLUHU-R100 on page 40
41 Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
80-INSRTH-E10
3–150 ng/mL
0.52 ng/mL
5 µL
Plasma, Serum
2h
Insulin Mouse ELISA
80-INSMS-E01
0.188–6.9 ng/mL
0.121 ng/mL
10 µL
Plasma, Serum
2h
Insulin Mouse ELISA Jumbo
80-INSMS-E10
0.188–6.9 ng/mL
0.121 ng/mL
10 µL
Plasma, Serum
2h
Insulin Ovine ELISA
80-INSOV-E01
0.15–4 ng/mL
0.14 ng/mL
25 µL
EDTA Plasma, Serum
2h 15m
Insulin Porcine/ Canine ELISA
80-INSPO-E01
0.05–2 ng/mL
0.007 ng/mL
25 µL
EDTA Plasma, Serum
2h 15m
Insulin Rat ELISA
80-INSRT-E01
0.15–5.5 ng/mL
0.124 ng/mL
10 µL
Plasma, Serum
2h
Insulin Rat ELISA Jumbo
80-INSRT-E10
0.15–5.5 ng/mL
0.124 ng/mL
10 µL
Plasma, Serum
2h
80-INSMR-CH01
0.1–150 ng/mL
0.096 ng/mL
5 µL
Plasma, Serum
2h
80-INSHUU-E01.1 *
0.15–20 µIU/mL
0.135 µIU/mL
25 µL
Plasma, Serum
1h 30m
Insulin Ultrasensitive Mouse ELISA
80-INSMSU-E01
0.025–6.9 ng/mL
0.115 ng/mL (5 µL), 0.019 ng/mL (25 µL)
5 µL, 25 µL
Plasma, Serum
2h 30m
Insulin Ultrasensitive Mouse ELISA Jumbo
80-INSMSU-E10
0.025–6.9 ng/mL
0.115 ng/mL (5 µL), 0.019 ng/mL (25 µL)
5 µL, 25 µL
Plasma, Serum
2h 30m
Insulin Ultrasensitive Rat ELISA
80-INSRTU-E01
0.15–5.5 ng/mL or 0.02–1 ng/mL
0.107 ng/mL (5 µL), 0.002 ng/mL (25 µL)
5 µL, 25 µL
Plasma, Serum
2h 30m
Insulin High Range Rat ELISA Jumbo
Insulin STELLUX™ Rodent ELISA Insulin Ultrasensitive ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Diabetes & Obesity Adiponectin Adiponectin circulates as multiple isoforms and is widely
Our HMW & Total Adiponectin ELISAs were developed
recognized as a key protein involved in insulin regulation
for the selective quantification of human or mouse
and metabolic syndrome. Measurement of high molecular
adiponectin oligomers using a patented protease
weight (HMW) levels, or the ratio of HMW to total
pretreatment. These ELISAs directly measure both HMW
adiponectin, has been shown to aid in predicting insulin
and total adiponectin, respectively.
resistance and the development of metabolic syndrome.1
1 Swarbrick MM, Austrheim‐Smith IT, Stanhope KL, et al. Circulating concentrations of high‐molecular‐weight adiponectin are increased following Roux‐en‐Y gastric bypass surgery. Diabetologia. Nov 2006; Vol 49 No 11: 2552‐2558.
42
View adiponectin assays 47-ADPHU-E01, 47-ADPMS-E01, 22-ADPRT-E01, and 47-ADPHUT-E01 on page 38
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
80-INSRTU-E10
0.02–1 ng/mL or 0.15–5.5 ng/mL
0.01 ng/mL (5 µL), 0.07 ng/ mL (25 µL)
5 µL, 25 µL
Plasma, Serum
2h 30m
Islet Cell Antibody ELISA
21-ICAHU-E01
Cut-off: See Protocol
See Protocol
25 µL
Serum
2h 30m
Leptin ELISA
11-LEPHU-E01
1–100 ng/mL
0.42 ng/mL
20 µL
Serum
1h 45m
Leptin Mouse/Rat ELISA
22-LEPMS-E01
15–1,600 pg/mL
10 pg/mL
5 µL
Serum
3h
Leptin RIA (Coated Tube)
22-LEP-R44
1–64 ng/mL
0.1 ng/mL
25 µL
Cell Culture, Plasma, Serum
Overnight
22-LEP-E077
0.05–5 ng/mL
0.01 ng/mL
10 µL
Biological Fluids, Plasma, Serum
1h 45m
22-LEP-R40
0.25–16 ng/mL
0.04 ng/mL
33 µL
Cell Culture, Cerebrospinal Fluid, Plasma, Serum, Urine
Overnight
MCP-1 ELISA
61-MCPHU-E01
15.6–1,000 pg/mL
2.3 pg/mL
20 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
MCP-1 Mouse ELISA
61-MCPMS-E01
15.6–1,000 pg/mL
2.2 pg/mL
50 µL
Cell Culture, Serum
3h 10m
MCP-1 Rat ELISA
45-MCPRT-E01
11.7–750 pg/mL
8 pg/mL
50 µL
Cell Culture, Plasma, Serum
2h 30m
24-MABHU-E01
0.5–100 µg/mL
0.24 µg/mL
10 µL
Urine
40m
Insulin Ultrasensitive Rat ELISA Jumbo
Leptin Ultrasensitive ELISA
Leptin Ultrasensitive RIA
Microalbumin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
30-1012
0.27–195 ng/mL
0.27 ng/mL
30 µL
Plasma, Serum
5h
NGAL Canine ELISA
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Canine ELISA
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA
54-036
10–1,000 pg/mL
4 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA
54-042
10–500 pg/mL
0.75 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA
54-044
10–400 pg/mL
1 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA
54-037
0.2–20 ng/mL
0.008 ng/mL
10 µL
EDTA Plasma, Plasma, Serum, Urine
1h
13-NPYHU-R100
9.4–300 pmol/L
6 pmol/L
200 µL
Plasma, Serum
48h
Obestatin ELISA
48-OBEHU-E01
0.231–25 ng/mL
0.231 ng/mL
20 µL
Plasma, Serum
Overnight
Obestatin Mouse/Rat ELISA
48-OBEMS-E01
0.082–20 ng/mL
0.082 ng/mL
25 µL
Serum
Overnight
61-PAIHU-E01
78–5,000 pg/mL
29 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
30-6410
440–28,000 mU/L
440 mU/L
100 mg
Stool
2h 15m
13-PPTHU-R100
6.25–200 pmol/L
3 pmol/L
100 µL
Serum
Overnight
Pepsinogen I ELISA
43-PE1HU-E01
3–300 ng/mL
0.1 ng/mL
50 µL
Serum
1h 20m
Pepsinogen II ELISA
43-PE2HU-E01
3–300 ng/mL
0.1 ng/mL
50 µL
Serum
2h 20m
80-PINHU-E01.1 *
2.5–180 pM
1.25 pM
50 µL
Heparin Plasma, Serum
2h
80-PINMS-E01
4–300 pM
1.5 pM
10 µL
Serum
2h 30m
80-PINRT-E01
4–300 pM
1.75 pM
10 µL
Serum
2h 30m
48-PYYHU-E01.1
0.082–20 ng/mL
0.082 ng/mL
50 µL
Plasma, Serum
Overnight
48-PYYRT-E01.1
0.15–12.5 ng/mL
0.31 ng/mL
25 µL
EDTA Plasma, Plasma, Serum
Overnight
30-6110
5.5–165 µg/mL
0.9 µg/L
20 µL
Plasma, Serum, Urine
2h 20m
41-RBPMS-E01
0.625–20 ng/mL
See Protocol
5 µL
Plasma, Serum
1h 10m
41-RBPRT-E01
6.25–200 ng/mL
See Protocol
5 µL
Plasma, Serum, Urine
1h 30m
Myostatin ELISA
NPY RIA
PAI-1 ELISA
Pancreatic Amylase ELISA Pancreatic Polypeptide RIA
Proinsulin ELISA Proinsulin Mouse ELISA Proinsulin Rat ELISA PYY ELISA PYY Mouse/Rat ELISA RBP ELISA RBP4 Mouse ELISA RBP4 Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
43
Diabetes & Obesity STELLUX™ Rodent Insulin ELISA
Off-site Laboratory Sample Results (ng/mL)
Inter-Lab Correlation Study
ALPCO’s STELLUX™ Rodent Insulin ELISA, has a broad dynamic range that significantly reduces sample preparation time by eliminating dilution steps and the guesswork involved in determining ideal dilution factors. The STELLUX™ Rodent Insulin ELISA can be run with either mouse or rat samples, as it detects isoforms of both rodent insulin genes. With no cross-reactivity to c-peptide
1000
Lab A Lab B Lab C
100
10
1
0.1
or proinsulin, this assay’s results are dependable and
0.1
1
10
100
1000
ALPCO Sample Results (ng/mL)
accurate. Inter-Lab Correlation Study with
• Broad range of 0.1 – 150 ng/mL 44
STELLUX™ Rodent Insulin ELISA (r2 value>0.99)
• Small sample size of 5 µL • 2 hour incubation
View the STELLUX assay 80-INSMR-CH01 on page 41
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
32-5179
0.25–20 ng/mL
0.05 ng/mL
10 µL
Cell Culture, Serum
2h 30m
22-RESHUU-E01
20–1,000 pg/mL
6 pg/mL
20 µL
Cell Culture, Plasma, Serum
4h
04-BI-20492
15–240 pM
2.6 pM
20 µL
EDTA Plasma, Heparin Plasma, Serum
Overnight
Sclerostin Mouse ELISA
41-SCLMS-E01
37.5–1,200 pg/mL
17.4 pg/mL
15 µL
Heparin Plasma, Serum
5h 20m
Serum Amyloid A ELISA
41-SAAHU-E01
0.157–10 ng/mL
0.157 ng/mL
10 µL
Plasma, Serum
1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E01
31.25–2,000 ng/mL
31.25 ng/mL
5 µL
Serum
1h 40m
Somatostatin RIA
13-RB 306
0–125 pmol/L
6 pmol/L
1 mL
Plasma
Overnight
TNF-α ELISA
45-TNFHU-E05
15–1,500 pg/mL
1.7 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
TNF-α ELISA
45-TNFHU-E01
15.6–1,500 pg/mL
1.7 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
TNF-α Monkey ELISA
61-TNAMK-E01
28.1–1,800 U/mL
6 U/mL
50 µL
Cell Culture, Serum
3h 10m
Resistin Rat ELISA Resistin Ultrasensitive ELISA Sclerostin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
61-TNFMS-E01
15.6–1,000 pg/mL
3 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
45-TNFPO-E01.1
23.4–1,500 pg/mL
4 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
5h
61-TNART-E01
39.1–2,500 pg/mL
11 pg/mL
50 µL
Cell Culture, Serum
3h 10m
TNF-α Ultrasensitive ELISA
45-TNFHUU-E01
0.5–32 pg/mL
0.09 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h
TNF-α Ultrasensitive ELISA
45-TNFHUU-E05
0.5–32 pg/mL
0.09 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h
22-VASHU-E01
10–1,000 pg/mL
4 pg/mL
70 µL
Serum
3h 30m
TNF-α Mouse ELISA
TNF-α Porcine ELISA
TNF-α Rat ELISA
Vaspin ELISA
45
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Endocrinology
46
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Endocrinology Endocrinology is the field of study which encompasses the functions of the endocrine system, its complex array of hormones and associated disorders. The endocrine system is comprised of a vast network of glands and chemically diverse messengers that interact to regulate coordinated activities with the nervous system in virtually all tissues. These chemical signaling molecules are called hormones, and they are classified by their different molecular structures. 47
Endocrine glands such as sweat,
Endocrine System
Hormones
sebaceous, mucous and digestive,
The endocrine system has five
Hormones fall into three categories:
secrete hormones into ducts which
broad functions:
deliver them to other parts of the body. At the same time, exocrine glands like the pituitary, thyroid, parathyroid and adrenals, secrete hormones into the extracellular
• Maintain fluid and chemical homeostasis • Regulate energy metabolism and balance • Govern adaptation to
• Amines, such as the catecholamines and thyroid hormones, contain a tyrosine backbone and are the simplest type of hormone • Protein and peptide hormones
space and are transported via
environmental stimuli such as
are chains of amino acids
capillaries to the blood. Organs that
trauma and stress
of varying length (including
have an endocrine function include the pancreas, testes, ovaries, kidneys, stomach, small intestine, skin, heart and placenta.
• Integrate coordinated development • Support reproductive
oxytocin and insulin) • Steroid hormones are derived from cholesterol, lipid soluble,
processes, from fertilization
and include the reproductive
to birth and nourishment of
hormones, glucocorticoids
the newborn
and mineralcorticoids
Endocrinology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
1,25 (OH)2 Vitamin D Extraction Kit
30-KM1100
See Protocol
See Protocol
500 µL
Plasma, Serum
1h 8m
33-10230
1–100 pg/mL
0.5 pg/mL
100 µL
Saliva
2h 15m
20-17OHU-E01 *
0.15–20 ng/mL
0.034 ng/mL
25 µL
Serum
1h 35m
20-17OHU-E01-SLV *
0.005–5 ng/mL
0.003 ng/mL
25 µL
Saliva
1h 15m
30-3400
4–1,250 nmol/L
4 nmol/L
500 µL
Plasma, Serum
See Protocol
5a-Androstane-3a, 17b-diol Glucuronide ELISA
11-ANDHU-E01
0.25–50 ng/mL
0.1 ng/mL
50 µL
Serum
45m
5a-Androstane-3a, 17b-diol Glucuronide LIA
11-ANDHU-L01
0.25–50 ng/mL
0.1 ng/mL
50 µL
Serum
30m
α-1-Antichymotrypsin ELISA
41-A1CHU-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
α-MSH RIA
13-RB 303
4.7–150 pmol/L
3 pmol/L
100 µL
Cerebrospinal Fluid, Plasma
Overnight
ß Endorphin RIA
13-RB 301
15.6–500 pmol/L
3 pmol/L
3 mL
Plasma
Overnight
25-FBEHU-E01
2.5–50 ng/mL
0.25 ng/mL
50 µL
Serum
1h 20m
ACE Kinetic
01-KK-ACK * ^
3–150 ACE units
5 ACE Units
25 µL
Serum
15m
ACE Kinetic
01-KK-ACK2 * ^
3–150 ACE Units
5 ACE Units
25 µL
Serum
15m
ACE Kinetic Jumbo (1200)
01-KK-ACKX * ^
3–150 ACE units
5 ACE Units
25 µL
Serum
15m
Acid Labile Subunit ELISA
22-ALS-E35
1.5–40 mU/mL
0.23 mU/mL
5 µL
Serum
3h
21-ACTHU-E01 *
5–500 pg/mL
0.46 pg/mL
200 µL
Plasma
5h
72-RENINE *
0–320 pg/mL
1 pg/mL
300 mL
Plasma
3h
AFP ELISA
25-AFPHU-E01
5–300 ng/mL
2 ng/mL
20 µL
Serum
1h 20m
Aldosterone ELISA
11-ALDHU-E01
20–2,000 pg/mL
15 pg/mL
100 µL
Serum, Urine
1h 15m
Aldosterone LIA
11-ALDHU-L01
20–2,000 pg/mL
4.24 pg/mL
200 µL
Serum, Urine
35m
Aldosterone RIA
72-ALDO-RIACT
7–1,500 pg/mL
7 pg/mL
200 µL, 200 µL, 10 µL
Plasma, Serum, Urine
3h
Androstenedione ELISA
11-ANRHU-E01 *
0.1–10 ng/mL
0.04 ng/mL
25 µL
Serum
1h 15m
32-5880
1–125 pg/mL
1 pg/mL
100 µL
Plasma
Overnight
01-RK-A22 *
2–500 pg/mL
1 pg/mL
1 mL
Plasma
Overnight
20-ASAHU-E01
62–500 U/mL
62 U/mL
10 µL
Plasma, Serum
1h 30m
14-HD-102.1 *
20–2,000 U/mL
8.2 U/mL
20 µL
Serum
2h
17 ß Estradiol ELISA (Saliva) 17-α-Hydroxy Progesterone ELISA 17-α-Hydroxy Progesterone ELISA (Saliva) 25-OH Vitamin D HPLC
48
ß hCG Free ELISA
ACTH ELISA Active Renin RIA
Angiotensin II ELISA Angiotensin II RIA Anti-Sperm Antibody ELISA Anti-TG LIA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
14-HD-103.1 *
30–3,000 U/mL
16.7 U/mL
20 µL
Serum
2h
Calcitonin ELISA
21-CALHU-E01 *
10–1,000 pg/mL
1 pg/mL
100 µL
Serum
4h 30m
Calcitonin Mouse/Rat IRMA
31-CALRT-R100
12–1,800 pg/mL
0.6 pg/mL
200 µL
Cell Culture, Plasma, Serum
Overnight
CCK RIA
13-CCKHU-R100
0.78–25 pmol/L
0.3 pmol/L
1 mL
Plasma
Overnight
Chromogranin A ELISA
43-CHRHU-E01.2
31–830 ng/mL
5 ng/mL
50 µL
EDTA Plasma
2h 20m
Chromogranin A RIA
13-RB 321
0.156–5 nmol/L
0.04 nmol/L
50 µL
Plasma
Overnight
c-Met ELISA (HGFR)
48-CMTHU-E01
0.78–50 ng/mL
0.26 ng/mL
100 µL
Cell Culture, EDTA Plasma, Plasma, Serum
2h
Corticosterone Mouse/Rat ELISA
55-CORMS-E01
15–2,250 ng/mL
4.5 ng/mL
10 µL
Plasma, Serum
2h 30m
Cortisol ELISA
11-CORHU-E01
0.5–60 µg/dL
0.4 µg/dL
20 µL
Serum
1h
11-CORHU-E01-SLV
1–100 ng/mL
1 ng/mL
50 µL
Saliva
1h
33-10110
10–500 ng/mL
10 ng/mL
10 µL
Urine
1h 15m
DHEA ELISA
20-DHEHU-E01 *
0.37–30 ng/mL
0.108 ng/mL
10 µL
Serum
1h 15m
DHEA-S ELISA
11-DHEHU-E01 *
0.005–10 µg/mL
5 pg/mL
25 µL
Serum
1h
33-10250
0.2–12 ng/mL
0.045 ng/mL
50 µL
Saliva
30m
DHT ELISA
11-DHTHU-E01
25–2,500 pg/mL
6 pg/mL
50 µL
Serum
1h 15m
EPO ELISA
21-EPOHU-E01 *
3–500 mIU/mL
0.6 mIU/mL
400 µL
Serum
2h 30m
Estradiol 17 ß ELISA
48-ESTHU-E01
16.5–4,000 pg/mL
16.5 pg/mL
100 µL
Water
Overnight
Estradiol ELISA
11-ESTHU-E01 *
20–3,200 pg/mL
10 pg/mL
50 µL
Serum
1h 15m
Estradiol RIA
72-ESTR-CTRIA
8–5,000 pg/mL
8 pg/mL
100 µL
Plasma, Serum
4h
20-ESTHUU-E01 *
3–200 pg/mL
3 pg/mL
100 µL
Plasma, Serum
4h 30m
72-ESTR-US-CT
10–2,000 pmol/L
5 pmol/L
200 µL
EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
33-10270
2.5–4,000 pg/mL
1.1 pg/mL
50 µL
Saliva
1h 15m
Estriol Free ELISA
20-FE3HU-E01 *
0.3–40 ng/mL
0.075 ng/mL
10 µL
Serum
1h 30m
Estrone ELISA
11-ESRHU-E01 *
15–2,000 pg/mL
10 pg/mL
50 µL
Serum
1h 15m
Estrone LIA
11-ESRHU-L01
15–2,000 pg/mL
8.8 pg/mL
50 µL
Serum
40m
Estrone-3-Sulfate Equine ELISA
55-E3SEQ-E01
5–1,000 ng/mL
0.14 ng/mL
20 µL
Serum
30m
25-FERHU-E01 *
15–1,000 ng/mL
5 ng/mL
20 µL
Serum
1h 5m
Anti-TPO LIA
Cortisol ELISA (Saliva) Cortisol ELISA (Urinary)
DHEA-S Salivary ELISA
Estradiol Ultrasensitive ELISA Estradiol Ultrasensitive RIA Estriol ELISA (Saliva)
Ferritin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
49
Endocrinology IGF-1 ELISA
measured IGF-I [pg/tube]
measured IGF-I [pg/tube]
10000
10000
0.5 ng IGFBP-3
Insulin-like Growth Factor 1 (IGF-1,
5 ng IGFBP-3
1000
1000
conventional
Somatomedin C) is one of several conventional
100
100
growth factors necessary for normal ALPCO
10
human development. ALPCO’s IGF-1
1
ELISA is an FDA registered kit which
1
ALPCO
10
10 10 100 1000 actual IGF-I[pg/tube]
10000
1
1
10 10 100 1000 actual IGF-I[pg/tube]
10000
provides results in-line with leading Minimal interference of IGFBP in IGF-I measurements
clinical methods.
with ALPCO assay versus conventional method IGF-1 is synthesized mainly by the liver, but also locally in many tissues. In contrast to many other peptide hormones, IGFs are avidly bound to specific 50
IGFBPs, which significantly increases the half-life of IGF-I in circulation. The seven classes of IGFBPs which are known at present 1, 2, 3 either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II. 4, 5 The predominant
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
FGF Basic ELISA
45-FGFHU-E01
15.6–1,000 pg/mL
7 pg/mL
50 µL
Cell Culture, Plasma, Serum
4h
FSH ELISA
11-FSHHU-E01 *
5–100 IU/L
1 IU/L
25 µL
Serum
1h 20m
Glutathione HPLC (GSH/GSSG)
30-1800
620–970 µmol/L
6 µmol/L
100 µL
EDTA Plasma, Plasma
See Protocol
Growth Hormone Human ELISA
25-HGHHU-E01 *
2.5–50 ng/mL
0.5 ng/mL
50 µL
Serum
1h
Growth Hormone Human RIA
72-HGH-RIACT
0.03–75 μIU/mL
0.03 μIU/mL
50 µL
Serum
2h 30m
Growth Hormone Mouse/Rat ELISA
22-GHOMS-E01
0.025–1.5 ng/mL
0.025 ng/mL
10 µL
Plasma, Serum
3h
32-5104
0.31–40 ng/mL
0.5 ng/mL
50 µL
Cell Culture, Plasma, Serum
Overnight
25-HCGHU-E01 *
5–300 mIU/mL
2 mIU/mL
50 µL
Serum
1h
Hepcidin 25 LC-MS
30-KM4000
See Protocol
1 ng/mL
See Protocol
Serum
See Protocol
Hepcidin ELISA (25 C-Terminal)
20-HCTHU-E01
2–80 ng/mL
2 ng/mL
20 µL
Plasma, Serum
1h 50m
Growth Hormone Rat ELISA hCG ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
IGFBP is IGFBP-3, which binds not only IGF-I but also the
interferents in the assay. With ALPCO’s IGF-1 ELISA,
Acid-labile Subunit. Thus, most of the IGF-I in circulation
there is no interference from IGFBP-3 so values can be
is bound within this ternary complex. IGFBPs can make
trusted, and it is traceable to international reference
the measurement of IGF-I very difficult, because if the
material of the WHO 02/254.
right methodology is not used, the IGFBPs become
1 Ballard J, Baxter R, Binoux M, et al. On the nomenclature of the IGF binding proteins. Acta Endocrinology. Nov 1989; Vol 121: 751-752. 2 Drop SLS. Report on the nomenclature of the IGF binding proteins. J Clin Endocrinology & Metabolism. Mar 1990; Vol 70 No 3: 817-818. 3 Wilson EM, Oh Y, Rosenfeld RG. Generation and characterization of an IGFBP-7 antibody: Identification of 31 kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinology & Metabolism. Apr 1997. Vol 82 No 4:1301-1303. 4 Martin JL, Baxter RC. Insulin-like growth factor binding protein from human plasma. Purification and characterization. J Biol Chem. Jul 1986; Vol 261: 8754-8760. 5 Binkert C, Landwehr J, Mary JL, et al. Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2). EMBO J. Sep 1989; Vol8 No9: 2497-2502.
View the IGF-1 ELISA assay 22-IGFHU-E01 on page 51
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Hepcidin Prohormone ELISA
20-HEPHU-E01
10–1,000 ng/mL
4 ng/mL
50 µL
Serum, Urine
3h 30m
Homocysteine ELISA
66-HCYHU-E01
2–50 µmol/L
1 µmol/L
25 µL
EDTA Plasma, Serum
See Protocol
HPL ELISA
20-HPLHU-E01
1.25–20 mg/L
0.3 mg/L
10 µL
Serum
40m
22-HGHHUU-E01 *
50–1,000 pg/mL
1.6 pg/mL
10 µL
Plasma, Serum
3h 15m
IGF-1 Direct RIA
22-IGF-R20 *
0.156–10 ng/mL
0.02 ng/mL
5 µL
Cell Culture, Plasma, Serum
Overnight
IGF-1 Direct RIA
22-IGF-R21 *
0.156–10 ng/mL
0.02 ng/mL
5 µL
Cell Culture, Plasma, Serum
Overnight
IGF-1 Direct RIA (Coated Tube)
22-IGF-R22 *
0.37–30 ng/mL
0.1 ng/mL
10 µL
Plasma, Serum
Overnight
22-IGFHU-E01 *
2–50 ng/mL
0.09 ng/mL
10 µL
Plasma, Serum
1h 45m
IGF-1 Mouse/Rat ELISA
22-IG1MS-E01
0.5–18 ng/mL
0.029 ng/mL
5 µL
Plasma, Serum
2h
IGF-1 RIA
72-IGF1-RIACT
0–835 ng/mL
1 ng/mL
25 µL
Plasma, Serum
4h 30m
Human Growth Hormone Ultrasensitive ELISA
IGF-1 ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
51
Endocrinology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
IGF-2 ELISA
22-IGF-E30
0.45–9 ng/mL
0.02 ng/mL
5 µL
Cerebrospinal Fluid, Plasma, Serum, Stool, Urine
3h
IGF-2 RIA
22-IGF-R30
0.4–50 ng/mL
0.1 ng/mL
10 µL
Cell Culture, Plasma, Serum
Overnight
IGF-2 RIA
22-IGF-R31
0.4–50 ng/mL
0.1 ng/mL
10 µL
Cell Culture, Plasma, Serum
Overnight
IGFBP-1 ELISA
11-IGFHU-E01
1–250 µg/L
0.5 µg/L
25 µL
Serum
1h 10m
IGFBP-2 ELISA
22-IGF-E05
2–80 ng/mL
0.2 ng/mL
15 µL
Breast Milk, Cell Culture, EDTA Plasma, Plasma, Saliva, Serum
1h 45m
IGFBP-2 Mouse/Rat ELISA
22-MIGF-E08
31.25–2,000 pg/mL
0.01 ng/mL
10 µL
Serum
2h 30m
IGFBP-3 ELISA
22-IGF-E03A
6.6–20 ng/mL
6.6 ng/mL
10 µL
Plasma, Serum
2h 30m
IGFBP-3 ELISA (Bioactive)
22-IGF-E04A
0.4–30 ng/mL
2 ng/mL
50 µL
EDTA Plasma, Heparin Plasma, Plasma, Serum
3h 30m
IGFBP-3 Mouse/Rat ELISA
22-MIGF-E031
0.078–5 ng/mL
0.018 ng/mL
5 µL
Cell Culture, Plasma, Serum
2h 30m
IGFBP-3 RIA
22-IGF-R10
0.625–40 ng/mL
0.06 ng/mL
50 µL
Plasma, Serum
Overnight
IGFBP-3 RIA (Coated Tube)
22-IGF-R11
1–81 ng/mL
0.5 ng/mL
10 µL
Plasma, Serum
Overnight
31-IPTBO-E01
0–10,000 pg/mL
10 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h 30m
Luteinizing Hormone ELISA
11-LUTHU-E01 *
1–100 IU/L
0.2 IU/L
25 µL
Serum
1h 20m
Lutenizing Hormone ELISA (Urine)
20-LHUHU-E01
10–200 mIU/mL
10 mIU/mL
25 µL
Urine
40m
30-1012
0.27–195 ng/mL
0.27 ng/mL
30 µL
Plasma, Serum
5h
55-PAPHUU-E01
11.25–450 ng/mL
0.023 ng/mL
100 µL
Serum
45m
20-PMSHU-E01
See Protocol
See Protocol
100 µL
Plasma, Serum
2h 30m
30-6331
1.6–100 ng/mL
3 ng/mL
100 mg
Plasma, Serum, Stool
2h 15m
41-PALMS-E01
15.625–500 ng/mL
15.625 ng/mL
5 µL
Plasma, Serum
1h
41-PALRT-E01
15.625–500 ng/mL
15.625 ng/mL
5 µL
Plasma, Serum
1h
Pregnenolone ELISA
11-PREHU-E01 *
0.1–25.6 ng/mL
0.05 ng/mL
50 µL
Serum
1h 45m
Progesterone ELISA
11-PROHU-E01 *
0.3–60 ng/mL
0.1 ng/mL
25 µL
Serum
1h 10m
Progesterone ELISA (Direct Saliva)
11-PROHU-E01-SLV
20–5,000 pg/mL
20 pg/mL
1 mL
Saliva
1h 10m
11-PROHU-L01
0.3–100 ng/mL
0.1 ng/mL
25 µL
Serum
35m
52
Intact PTH Bovine ELISA
Myostatin ELISA PAPP-A Ultrasensitive ELISA PMSG ELISA Prealbumin ELISA Prealbumin Mouse ELISA
Prealbumin Rat ELISA
Progesterone LIA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
55-PROMS-E01
0.4–100 ng/mL
0.04 ng/mL
25 µL
Plasma, Serum
1h 30m
72-PROG-CTRIA
0.1–60 ng/mL
0.05 ng/mL
50 µL
EDTA Plasma, Heparin Plasma, Plasma, Serum
2h 10m
55-PRLCA-E01
2.5–80 ng/mL
0.4 ng/mL
25 µL
Serum
3h 30m
25-PROHU-E01 *
5–200 ng/mL
2 ng/mL
50 µL
Serum
1h 5m
55-PRLRT-E01
5–80 ng/mL
0.6 ng/mL
25 µL
Serum
3h 30m
PSA Total ELISA
25-PSAHU-E01
2–120 ng/mL
1 ng/mL
50 µL
Serum
2h 20m
PTH Bioactive Intact Rat ELISA
31-BIPRT-E01
25–2,700 pg/mL
3 pg/mL
25 µL
Cell Culture, Plasma
3h 30m
31-IPTHUU-E01
3.2–143 pg/mL
0.3 pg/mL
150 µL
Cell Culture, EDTA Plasma, Plasma
3h 30m
PTH Intact ELISA (1-84)
21-IPTHU-E01 *
7–700 pg/mL
1.57 pg/mL
25 µL
Serum
3h 30m
PTH Intact Mouse ELISA (1-84)
31-PTHMS-E01
32–1,045 pg/mL or 336–2,616 pg/mL
4 pg/mL
20 µL
Cell Culture, Plasma
3h 30m
PTH Intact Porcine ELISA
31-IPTPO-E01
0–1,000 pg/mL
1 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h 30m
PTH Intact Rat ELISA (1-84)
31-IPTRT-E01
25–2,700 pg/mL
1.6 pg/mL
25 µL
Cell Culture, Plasma, Serum
3h 30m
30-9210
4–250 pg/mL
4 pg/mL
100 µL
Plasma, Serum, Tissue Culture, Urine
Overnight
Renin Activity ELISA
11-RENHU-E02
0.2–60 ng/mL
0.038 ng/mL
50 µL
EDTA Plasma, Plasma
1h 45m
Renin Activity LIA
11-RENHU-L02
0.2–25 ng/mL
0.08 ng/mL
500 µL
EDTA Plasma, Plasma
1h 30m
Renin ELISA
20-RENHU-E01
0.81–28 pg/mL
0.81 pg/mL
50 µL
EDTA Plasma
3h 15m
38-RT3HU-R125
0.025–2 ng/mL
0.009 ng/mL
100 µL
Amniotic Fluids, Plasma, Serum
3h
11-SHBHU-E01
3.3–295 nmol/L
0.1 nmol/L
10 µL
Serum
1h
13-RB 306
0–125 pmol/L
6 pmol/L
1 mL
Plasma
Overnight
T3 Free ELISA
25-FT3HU-E01
0.9–19 pg/mL
0.05 pg/mL
50 µL
Serum
1h 20m
T3 Total ELISA
25-TRIHU-E01 *
0.75–10 ng/mL
0.2 ng/mL
50 µL
Serum
1h 20m
T3 Total RIA
14-HD-131.100
0.8–10 nmol/L
0.3 nmol/L
50 µL
Serum
2h
T4 Free ELISA
25-FT4HU-E01
0.3–7 ng/dL
0.05 ng/dL
50 µL
Serum
1h 20m
T4 Free LIA
11-FT4HU-L01
0–120 pg/mL
1 pg/mL
50 µL
Serum
45m
T4 Total ELISA
25-TT4HU-E01 *
2–25 µg/dL
0.4 µg/dL
25 µL
Serum
1h 20m
T4 Total RIA
14-HD-141.100
25.6–512 nmol/L
12.8 nmol/L
50 µL
Serum
2h
Progesterone Mouse/ Rat ELISA Progesterone RIA Prolactin Canine ELISA Prolactin ELISA Prolactin Rat ELISA
PTH High Sensitive ELISA (1-34)
Relaxin ELISA
Reverse T3 RIA SHBG ELISA Somatostatin RIA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
53
Endocrinology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
TBG RIA
14-HD-53.1
5–80 mg/L
5 mg/L
20 µL
Serum
2h
11-TESHU-E01-SLV
2–800 pg/mL
1 pg/mL
1 mL
Saliva
1h 40m
Testosterone ELISA (Serum)
11-TESHU-E01 *
0.08–16.7 ng/mL
0.022 ng/mL
50 µL
Serum
1h 10m
Testosterone Free ELISA
11-FTSHU-E01 *
0.25–125 pg/mL
0.17 pg/mL
25 µL
Serum
1h 15m
Testosterone Free LIA
11-FTSHU-L01
0.25–100 pg/mL
0.17 pg/mL
25 µL
Serum
1h
Testosterone LIA (Saliva)
11-TESHU-L01
2–800 pg/mL
1 pg/mL
1 mL
Saliva
1h 10m
Testosterone Mouse/ Rat ELISA
55-TESMS-E01
0.1–25 ng/mL
0.066 ng/mL
10 µL
Plasma, Serum
30m
Testosterone RIA
72-TESTO-CT2
0.5–50 nmol/L
0.3 nmol/L
25 µL
Serum
1h
14-HD-27.1 *
20–2,000 IU/mL
5.5 IU/mL
20 µL
Plasma, Serum
2h
27-GD101
10–400 ng/mL
2 ng/mL
50 µL
Serum
1h 40m
Thyroglobulin Plus ILMA
14-HD-111.1
0.15–250 ng/mL
0.02 ng/mL
100 µL
Serum
Overnight
Thyroglobulin Plus IRMA
14-HD-110.1 *
0.15–250 ng/mL
0.2 ng/mL
100 µL
Serum
1h 20m
14-HD-90.1 *
30–3,000 U/mL
5.5 U/mL
90 µL
Serum
1h
55-TSHCA-E01
0.2–5.2 ng/mL
0.01 ng/mL
100 µL
EDTA Plasma, Plasma, Serum
2h 30m
TSH ELISA
25-TSHHU-E01 *
0.5–25 µIU/mL
0.2 µIU/mL
100 µL
Serum
1h 20m
TSH IRMA
14-HD-09.1
0.16–80 MU/L
0.04 mU/L
100 µL
Serum
1h
TSH LIA
11-TSHHU-L01
0.008–25 µIU/mL
0.002 µIU/mL
50 µL
Serum
1h
TSH Rat ELISA
55-TSHRT-E01
0.1–80 ng/mL
0.1 ng/mL
25 µL
Serum
Overnight
TSH Receptor Autoantibodies LRA
14-HD-107.1 *
1–40 IU/L
0.4 IU/L
100 µL
Serum
3h
TSH Receptor Autoantibodies RIA
14-HD-77.1
5–405 U/L
2.4 U/L
50 µL
Serum
2h 15m
14-HD-101.1
1–40 IU/L
0.3 IU/L
100 µL
Serum
3h
25-TSHHUU-E01 *
0.1–10 µIU/mL
0.05 µIU/mL
100 µL
Serum
2h 20m
13-RB 311
3.8–120 pmol/L
3 pmol/L
200 µL
Serum
Overnight
01-RK-VPD ^
1.25–80 pg/mL
0.75 pg/mL
1 mL
EDTA Plasma
Overnight
01-RK-AR1
0.63–80 pg/mL
0.4 pg/mL
1 mL
EDTA Plasma, Urine
Overnight
30-3420
4–1,250 nmol/L
4 nmol/L
500 µL
Plasma, Serum
See Protocol
Testosterone Direct Saliva ELISA
Thyroglobulin Ab RIA Thyroglobulin ELISA
54
TPO Ab RIA TSH Canine ELISA
TSH RRA Receptor Ab RIA TSH Ultrasensitive ELISA Vasoactive Intestinal Peptide RIA Vasopressin Direct RIA (ADH/AVP) Vasopressin Ultrasensitive RIA (ADH/AVP) Vitamin D2/D3 HPLC
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
55
Gastroenterology
56
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Gastroenterology is the branch of medicine that deals with the study and treatment of the digestive system (comprised of stomach and intestine) and related disorders affecting it. Gastric diseases and ailments have become a growing therapeutic segment of interest due to an increased prevalence of irregular dietary habits and poor hygiene factors across the world.
57
Calprotectin Calprotectin is considered a reliable indicator of
clinical symptoms, but it has been reported that the
inflammation in several diseases. Both organic
recognized activity indexes are subjective and do not
Inflammatory Bowel Disease (IBD) and non-organic
correlate as consistently as fecal calprotectin levels with
functional disorders like Irritable Bowel Syndrome
histologic inflammation.7,8
(IBS) exhibit very similar symptoms. Research has shown the concentration of calprotectin in feces may
Fecal calprotectin has been demonstrated to be
be significantly elevated in cases of IBD, whereas
a reliable biomarker of mucosal inflammation in
in cases of IBS, levels remain normal. 1,2,3 Thus,
several organic IBD pathologies and may function as
measurement of fecal calprotectin may be useful for
a valuable alternative to relying on clinical symptoms,
the differential diagnosis and potential management
the use of complex imaging procedures, or performing
of organic Inflammatory Bowel Disease. 4,5,6
endoscopy and/or biopsy. Because of the strong correlation between calprotectin and disease activity,
Measurement of fecal calprotectin levels may provide
many research studies conclude that monitoring fecal
physicians with valuable information for timely
calprotectin levels can be useful for chronicling disease
decision making on whether to send IBD patients for
activity in IBD.7,8,9 Increased levels of calprotectin as an
colonoscopy, or rather treat them for IBS symptoms.
indicator of inflammation also precedes the appearance
Traditionally, IBD activity has been assessed through
of clinical symptoms.
Gastroenterology Research has shown that IBD is marked by periods of
Differentiation of IBD vs. IBS
remission with intermittent relapses characterized by
Fecal calprotectin is a reliable surrogate marker for
increased intestinal inflammation. Thus, monitoring levels
differentiating organic inflammation (IBD) from functional
of fecal calprotectin may become essential in determining
symptoms (IBS). 4-12
the effectiveness of therapy and could become a predictor of potential relapse. It provides physicians with a valuable
Predicting Relapse
tool, not only for differentiating IBD from IBS cases, but
Calprotectin has been shown in numerous publications to
also allowing them to monitor and predict treatment
be a reliable predictor of IBD in remission. 4-12
outcomes, enabling better management of IBD flares.4-12
Disease Monitoring Low calprotectin levels after treatment (<250 µg/g) 58
indicate endoscopic mucosal healing. This can assist in optimizing treatment in IBD patients. 4-12
1 Røseth AG, Fagerhol MK, Aadland E, Schjønsby H. Assessment of the
2 Manz M, Burri E, Rothen C, Tchanguizi N, et al. Value of fecal calprotectin
neutrophil dominating protein calprotectin in feces. A methodologic study.
in the evaluation of patients with abdominal discomfort: an observational
Scand J Gastroenterology. Sep 1992; Vol 27 No 9:793-8.
study. BMC Gastroenterology. Jan 2012; Vol 12 No 1:5.
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
α-1-Antichymotrypsin ELISA
41-A1CHU-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
α-1-Antitrypsin Mouse ELISA
41-A1AMS-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Serum
2h 5m
α-Fodrin Check IgG/IgA ELISA
35-AFCHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
30-2112
5.1–200 pg/mL
4.8 pg/mL
500 µL
Plasma, Serum
Overnight
30-KM1100
See Protocol
See Protocol
500 µL
Plasma, Serum
1h 8m
25-OH Vitamin D ELISA
30-2109
2–300 nmol/L
2 nmol/L
30 µL
Serum
Overnight
25-OH Vitamin D HPLC
30-3400
4–1,250 nmol/L
4 nmol/L
500 µL
Plasma, Serum
See Protocol
1,25 (OH)2 Vitamin D ELISA 1,25 (OH)2 Vitamin D Extraction Kit
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
3 Røseth AG, Schmidt PN, Fagerhol MK. Correlation between faecal excretion
Feb 2012. Vol 18 No 12: 2218-24.
of indium-111-labelled granulocytes and calprotectin, a granulocyte
9 Lobatón T, Rodríguez-Moranta F, Lopez A, et al. A new rapid quantitative
marker protein, in patients with inflammatory bowel disease. Scand J
test for fecal calprotectin predicts endoscopic activity in ulcerative colitis.
Gastroenterology. Jan 1999; Vol 34 No1:50-4.
Inflamm Bowel Disease. Apr 2013. Vol 19 No 5: 1034-1042.
4 Tibble J.A., Bjarnason I. et al. Surrogate markers of intestinal inflammation
10 Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission
are predictive of relapse in patients with inflammatory bowel disease.
among patients with Crohn’s disease on antimetabolite therapy after
Gastroenterology Jul 2000; Vol 119 No 1: 15-22.
infliximab therapy is stopped. Gastroenterology. Jan 2012; Vol 142 No 1:
5 Røseth AG, Aadland E, Grzyb K. Normalization of faecal calprotectin: a
63-70.
predictor of mucosal healing in patients with inflammatory bowel disease.
11 De Vos M, Dewit O, D’Haens G, et al. Fast and sharp decrease in calprotectin
Scand J Gastroenterology. Oct 2004; Vol 39 No 10: 1017-1020.
predicts remission by infliximab in anti-TNF naïve patients with ulcerative
6 Lewis, JD. The utility of biomarkers in the diagnosis and therapy of
colitis. J Crohns Colitis. Jun 2012; Vol 6 No 5: 557-62.
inflammatory bowel disease. Gastroenterology. May 2011; Vol 140 No 6:
12 Sorrentino D, Terrosu G, Paviotti A, et al. Early diagnosis and treatment of
1817-1826.
postoperative endoscopic recurrence of Crohn’s disease: partial benefit by
7 Burri E, Beglinger C. Faecal calprotectin - a useful tool in the management of
infliximab--a pilot study. Digestive Diseases and Sciences. May 2012; Vol 57
inflammatory bowel disease. Swiss Med Weekly. Apr 2012; Vol 142.
No 5: 1341-1348.
8 D’Haens G, Ferrante M, et al. Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease. Inflamm Bowel Disease.
View calprotectin assays 01-EK-CAL, 01-LF-CHR25, 01-LF-CAL25, and 01-DS-CAL25 on page 60
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
30-9510
4–1,000 ng/mL
4 ng/mL
200 µL
Serum, Tissue Culture
Overnight
Anti-Casein IgA ELISA
27-GD42
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Gliadin IgA ELISA
27-GD17
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
Anti-Gliadin IgA/IgG ELISA
27-GD77
6.25–100 U/mL
0.5 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Gliadin IgG ELISA
27-GD16
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
Anti-Helicobacter Pylori IgA ELISA
27-GD08
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori IgG ELISA
27-GD01
6.25–100 U/mL
6.25 U/mL
10 µL
Plasma, Serum
1h 10m
Alpha-1 Thymosin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
59
Gastroenterology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
27-GD124
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
50m
Anti-Human Tissue Transglutaminase sIgA ELISA
30-9393
Cut-off: See Protocol
See Protocol
100 mg
Stool
2h 30m
Anti-Ovalbumin IgA ELISA
27-GD40
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Ovalbumin IgG ELISA
27-GD41
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Soya IgA ELISA
27-GD44
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-TNF α Inhibitor ELISA (Antibody Against ENBREL®)
30-9653
Cut-off: See Protocol
See Protocol
100 µL
Serum
Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652
Cut-off: See Protocol
See Protocol
100 µL
EDTA Plasma, Serum
Overnight
Biotin ELISA
30-8140
37.5–600 ng/L
15 ng/L
150 µL
Serum, Urine
1h 15m
30-KIF007
0.02–0.18 µg/L
0.02 µg/L
100 µL
Serum
Overnight
01-DS-CAL25
Cut-off: See Protocol
See Protocol
See Protocol
Stool
10m
Calprotectin ELISA
01-EK-CAL ^ †
10–600 µg/g or 30–1,800 µg/g
10 µg/g
50 mg
Stool
1h 15m
Calprotectin ELISA (2x96 Wells)
01-EK-CAL-02 ^
10–600 µg/g or 30–1,800 µg/g
10 µg/g
50 mg
Stool
1h 15m
30-6936
0.25–15.6 ng/mL
0.076 ng/mL
100 µL
Cell Culture, Plasma, Serum, Stool, Tissue Culture, Urine
4h 20m
Calprotectin Quantum Blue® High Range Rapid Test
01-LF-CHR25 ^
100–1,800 µg/g
100 µg/g
80 mg
Stool
15m
Calprotectin Quantum Blue® Rapid Test
01-LF-CAL25 ^
30–300 µg/g
10 µg/g
80 mg
Stool
12m
Care™ FOB Rapid Testing Kit (20 tests)
43-FOBHU-RP20 *
See Protocol
0.05 µg h-Hb/mL
See Protocol
Stool
5m
Care™ FOB Rapid Testing Kit (50 tests)
43-FOBHU-RP50 *
See Protocol
0.05 µg h-Hb/mL
See Protocol
Stool
6m
Casomorphin ELISA
30-7010
1–120 ng/mL
1 ng/mL
2 mL
Urine
Overnight
01-EK-CAST
50–3,200 pg/mL
20 pg/mL
2 mL
Whole Blood
2h 30m
Anti-Helicobacter Pylori IgM ELISA
60
Biotin Microbiological Assay Calprotectin CALcheck Blue™ Dipstick (25 tests)
Calprotectin Mouse/ Rat ELISA
CAST® ELISA (Leukotriene Function)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
†
Pending FDA Clearance
Food Intolerance ALPCO offers a number of assays for the measurement of
and coded to ensure accurate reagent dispensing. The
food-specific proteins such as gliadin, ovalbumin, casein,
assays require minimal pipetting steps, making them
and soya. Kits contain reagents which are ready-to-use
convenient for manual processing if needed.
Description CAST® ELISA Jumbo (Leukotriene Function) CeliCheck ELISA (Tissue Transglutaminase IgA/IgG ELISA)
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
01-EK-CAST5
50–3,200 pg/mL
20 pg/mL
2 mL
Whole Blood
2h 30m
35-CELHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 30m
61
Chymotrypsin Activity Assay
30-6990
13.2 U/g
See Protocol
100 µL
Stool
5m
Chymotrypsin ELISA
30-6910
20–1,000 ng/mL
20 ng/mL
100 mg
Stool
2h 30m
35-CROHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
DAO ELISA
30-8500
0–15.65 U/mL
0.052 U/mL
50 µL
Serum
4h 20m
EDN ELISA
30-6811
0.25–16 ng/mL
0.165 ng/mL
80 mg, 20 µL
Plasma, Serum, Stool, Urine
2h 20m
01-FK-HSBAT ^
See Protocol
See Protocol
100 µL
Whole Blood
1h
FlowCAST® Basophil Activation Test
01-FK-CCR
See Protocol
See Protocol
50 µL
Whole Blood
30m
Folic Acid Vitamin B9 Microbiological Test Kit
30-KIF005
4–40 µg/L
4 µg/L
100 µL
Serum
Overnight
Gastrin RIA
13-MD 302 *
15.6–500 pmol/L
5 pmol/L
100 µL
Serum
1h 45m
Gastrin RIA
72-GASK-PR
0–500 μU/mL
10 μU/mL
100 µL
Plasma, Serum
3h
Gliadorphin ELISA
30-7011
3–30 ng/mL
2 ng/mL
2 mL
Urine
Overnight
Hemoglobin/Haptoglobin ELISA
30-7817
0.1–3.5 U/L
0.30 U/L
100 mg
Stool
2h 20m
41-LACHU-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Milk, Plasma, Serum
1h 15m
30-6900
1.1–30 ng/mL
0.5 ng/mL
100 mg, 15 mg
Stool
2h 20m
Crohns Check ELISA (Anti-Saccharomyces Cerevisiae IgA/IgG ELISA)
FlowCAST Highsens® High Sensitivity Basophil Activation Test
Lactoferrin ELISA Lysozyme ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Gastroenterology Secretory IgA Secretory IgA is a marker of intestinal immune status and
Measuring levels of Secretory IgA may aid in the
is a major immunoglobulin in gastrointestinal secretions.
understanding of intestinal immune status. A low sIgA-
Secretory IgA is an important factor in mucosal immunity
level may indicate reduced activity of the intestinal
and in the intraluminal microbial defense system. It plays
immune system, while an elevated sIgA-level may be
a role in preventing adherence of microorganisms to
indicative of immune system activation of the gut mucosa
mucosal sites, in activation of the alternative complement
caused by pathogens or allergic processes.1
pathway and in activating inflammatory reactions.
1 Yel, L. Selective IgA Deficiency. J Clinical Immunology. Jan 2010; Vol 30 No 1: 10–16.
62
View secretory IgA assays 30-8870, 30-6863, and 30-6864 on page 62
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
30-6902
1.1–30 ng/ml
0.5 ng/ml
100 µL
See Protocol
2h 20m
01-EK-MRP8/14
0.4–24 µg/mL
0.4 µg/mL
10 µL
Plasma, Serum
1h 15m
30-KIF003
4–40 µg/L
4 µg/L
150 µL
Serum
Overnight
Pepsinogen I ELISA
43-PE1HU-E01
3–300 ng/mL
0.1 ng/mL
50 µL
Serum
1h 20m
Pepsinogen II ELISA
43-PE2HU-E01
3–300 ng/mL
0.1 ng/mL
50 µL
Serum
2h 20m
q-FOB™ Immunochemical Test (FIT) Kit
43-FOBHU-E01
0–82 ng/mL
2.6 ng/mL
100 µL
Stool
40m
Riboflavin Microbiological Assay Kit (Vitamin B2)
30-KIF002
5–60 ng/L
5 ng/L
150 µL
Serum
Overnight
S100A12 ELISA
30-6938
0.22–6 ng/mL
0.016 ng/mL
100 mg
Stool
2h
Secretory IgA ELISA
30-8870
22.2–600 ng/mL
13.4 ng/mL
100 mg, 10 µL
Saliva, Stool
2h 10m
Secretory IgA1 ELISA
30-6863
3.3–100 U
3.3 U
100 mg
Stool
2h 15m
Secretory IgA2 ELISA
30-6864
3.3–100 U
3.3 U
100 mg
Stool
2h 15m
ß Defensin 2 ELISA
30-6500
0.1–3 ng/mL
0.077 ng/mL
100 mg
Stool
3h 30m
30-KIF001
3–15 ng/L
3 ng/L
100 µL
Whole Blood
Overnight
Lysozyme ELISA (Serum, Urine, Liquor) MRP 8/14 ELISA Niacin MicroBiological Assay Kit (Vitamin B3)
Thiamin Microbiological Assay Kit (Vitamin B1)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
13-RB 311
3.8–120 pmol/L
3 pmol/L
200 µL
Serum
Overnight
Vitamin A and Vitamin E HPLC Assay (Retinol and Tocopherol HPLC Assay)
30-1600
See Protocol
0.05 mg/mL
100 µL
EDTA Plasma, Serum
See Protocol
Vitamin B1 HPLC
30-2201
12–192 nmol/L
0.13 nmol/L
50 µL
Plasma
1h 35m
Vitamin B12 MicroBiological Test Kit
30-KIF012
6–54 µg/L
6 µg/L
75 µL
Serum
Overnight
Vitamin B5 Pantothenic Acid Microbiological Assay
30-KIF004
0.36–3.6 µg/L
0.36 µg/L
300 µL
Serum
Overnight
Vitamin B6 Enzymatic Assay
01-KK-VB6
9–250 nM
7 nM
25 µL
EDTA Plasma
45m
Vitamin B6 HPLC
30-2100
4.3–17.9 ng/mL
0.2 ng/mL
200 µL
EDTA Plasma, Plasma, Serum
See Protocol
30-KIF006
0.36–3.6 µg/L
0.36 µg/L
300 µL
Serum
Overnight
Vitamin C HPLC (Ascorbic Acid)
30-2900
4–20 mg/L
0.25 mg/L
200 µL
Heparin Plasma, Plasma
See Protocol
Vitamin D Binding Protein ELISA
30-2314
2.2–60 ng/mL
1.23 ng/mL
10 µL
Plasma, Serum, Urine
2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 30m
Vitamin K1 HPLC
30-2400
See Protocol
0.15 ng/mL
1 mL
Plasma, Serum
See Protocol
Zonulin ELISA
30-5600
0–1,000 ng/mL
0.6 ng/mL
250 µL
Stool
3h 10m
Zonulin ELISA (Serum)
30-5601
See Protocol
0.6 ng/mL
See Protocol
Serum
3h 10m
Vasoactive Intestinal Peptide RIA
Vitamin B6 MicroBiological Assay
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
63
Immunology
64
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology Immunology is the branch of biomedical science that is concerned with the relationship between body systems, pathogens and immunity. The central science of immunology is the study of the molecular and cellular components that comprise the immune system, including their function and interaction. ALPCO offers tools that can be used to gain insight into the development or progression of immune responses.
65
Innate vs. Adaptive Immune System The immune system is comprised of two subdivisionsâ&#x20AC;&#x201D;the innate immune system (non-specific) and the adaptive immune system (specific). Innate Immune System
The internal defenses consist of cells
substances and act to neutralize or
The innate system attempts to
and chemicals. The predominant
destroy them. Three types of cells
protect the body from all invaders.
cell types involved are phagocytes
play the major roles in the adaptive
The elements of this system include
and natural killer cells. In response
immune system: B lymphocytes (B
surface barriers and internal
to microorganisms, these cell
cells), T lymphocytes (T cells) and
defenses. The two surface barriers
types release chemicals and
antigen-presenting cells (APCs).
are skin and mucosae. The skin
antimicrobial proteins as a part of
Following exposure of these cell
provides a nearly impenetrable
the inflammatory response.
types to an antigen, they retain the
barrier to microorganisms and
ability to recognize the same antigen
fluids secreted onto the skin
Adaptive Immune System
in the future which leads to faster
contain chemicals that inhibit the
The adaptive system can initiate
immune system response time.
growth of microorganisms. Mucous
specific attacks against specific
membranes produce mucus to trap
invaders. This system consists of
microorganisms.
cells that recognize specific foreign
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
α-1-Acid Glycoprotein Chicken ELISA
41-AGPCH-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
α-1-Acid Glycoprotein ELISA
41-AGPHU-E01
5–320 ng/mL
5 ng/mL
5 µL
Plasma, Serum
1h 15m
α-1-Acid Glycoprotein Rat ELISA
41-AGPRT-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 20m
α-1-Antitrypsin Canine ELISA
41-A1ACA-E01
12.5–800 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 15m
30-6752
3.3–90 µg/L
1.8 mg/dL
10 µL, 100 mg
Plasma, Serum, Stool
2h 10m
α-1-Antitrypsin Mouse ELISA
41-A1AMS-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Serum
2h 5m
α-Fodrin Check IgG/IgA ELISA
35-AFCHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
72-AAI
See Protocol
See Protocol
50 µL
Plasma, Serum
2h 30m
01-KK-ACF
1–30 U/L
1 U/L
80 µL
Cerebrospinal Fluid
See Protocol
Active Dephosphorylated ß-Catenin ELISA (S33/S37/T41)
62-CATHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
AGP Canine ELISA
41-AGPCA-E01
6.17–1,500 ng/mL
6.17 ng/mL
5 µL
Plasma, Serum
1h 40m
AKT1/2 (pS473/pS474) and GSK3α/ß (pS21/pS9) ELISA
62-AGGHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 35m
AKT1/2 ELISA (pS473/pS474)
62-AKTHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
Alpha-Lactalbumin IgA ELISA
27-GD50
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Alpha-Lactalbumin IgG ELISA
27-GD51
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
ANA-8Pro ELISA
35-ANAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
ANA-8S IgG ELISA
35-AN8HU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
Annexin V ELISA
61-ANNHU-E01
0.78–50 ng/mL
0.33 ng/mL
50 µL
Cell Culture, Serum
3h 10m
Anti-ANCA IgG Screening ELISA
13-CP-111 *
Cut-off: See Protocol
See Protocol
25 µL
Serum
30m
Anti-Annexin V ELISA
61-AANHU-E01
6.3–400 ng/mL
1.2 ng/mL
50 µL
Cell Culture, Serum
2h 10m
Anti-ASCA IgA ELISA
27-GD79
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-BPI IgA ELISA
27-GD11
See Protocol
See Protocol
10 µL
Plasma, Serum
1h 40m
Anti-BPI IgG ELISA
27-GD05
3.1–100 U/mL
3.1 U/mL
10 µL
Plasma, Serum
1h 40m
α-1-Antitrypsin Clearance ELISA
AAI RIA
66
ACE Kinetic High Sensitive Assay (CSF Samples)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
01-EK-AC1QA
5–400 U/mL
1 U/mL
10 µL
Plasma, Serum
2h 15m
Anti-Cardiolipin IgA/IgG/IgM Screen ELISA
27-GD28
20–200 U/mL
1.9 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Cardiolipin IgG ELISA
27-GD26
20–200 U/mL
0.63 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Cardiolipin IgM ELISA
27-GD27
8–100 U/mL
0.2 U/mL
10 µL
Plasma, Serum
1h 10m
35-CAAHU-E01
3–300 APL/mL
1 APl/mL
10 µL
Serum
1h
Anti-Casein IgA ELISA
27-GD42
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Casein IgG ELISA
27-GD43
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-CaSR lgG ELISA
43-CASHU-E01
10–270 U/mL
2.5 U/mL
10 µL
Plasma, Serum
1h 50m
Anti-Cathepsin G ELISA
35-CATHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-CENP-B IgG ELISA
35-CENHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-Cytomegalovirus IgG ELISA
27-GD84
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Cytomegalovirus IgM ELISA
27-GD85
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-ds-DNA ELISA
27-GD10
12–200 IU/mL
1 IU/mL
10 µL
Plasma, Serum, Urine
1h
Anti-ds-DNA IgA/IgG/IgM Screen ELISA
35-DSSHU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum, Urine
1h
Anti-ds-DNA-A ELISA
35-DSAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-ds-DNA-G ELISA
35-DSGHU-E01
3–300 IU/mL
1 IU/mL
10 µL
Serum
1h
Anti-ds-DNA-M ELISA
35-DSMHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
35-ELAHU-E01
3–300 U/mL
1 U/mL
100 µL
Serum
1h
30-9396
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
2h 30m
Anti-GBM & ANCA Rapid Screen ELISA
13-GCP-100 *
See Protocol
See Protocol
25 µL
Serum
30m
Anti-GBM IgG ELISA
13-GP-104x *
10–320 U/mL
See Protocol
5 µL
Serum
2h
Anti-Gliadin IgA ELISA
27-GD17
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
Anti-Gliadin IgA/IgG ELISA
27-GD77
6.25–100 U/mL
0.5 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Gliadin IgG ELISA
27-GD16
6.25–100 U/mL
0.25 U/mL
10 µL
Serum
1h 10m
22-E10
10–50 mIU/mL
0.1 IU/mL
10 µL
Plasma, Serum
4h
Anti-C1q Autoantibodies ELISA
Anti-Cardiolipin-A ELISA
Anti-Elastase ELISA Anti-Epidermal Transglutaminase IgA ELISA
Anti-HAV ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
67
Immunology Description
68
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Anti-HAV IgG ELISA
68-4AGE3
See Protocol
See Protocol
10 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HAV IgM ELISA
68-4AME3
See Protocol
See Protocol
5 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Anti-HBc IgG ELISA
68-4CBE3
See Protocol
See Protocol
5 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HBc IgM ELISA
68-4CME3
See Protocol
See Protocol
5 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h 30m
Anti-HBs ELISA
68-4SBE3
See Protocol
See Protocol
50 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HCV ELISA
68-4NAE3
See Protocol
See Protocol
100 µL
Plasma, Serum
1h 45m
Anti-Helicobacter Pylori IgA ELISA
27-GD08
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori IgG ELISA
27-GD01
6.25–100 U/mL
6.25 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori IgM ELISA
27-GD124
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
50m
Anti-Helicobactor Pylori ELISA
30-6920
Cut-off: See Protocol
See Protocol
100 mg
Stool
3h
Anti-Herpes-1/2 IgM ELISA
27-GD88
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Histone C IgG ELISA
35-HSCHU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h
Anti-Histone H1 IgG ELISA
35-HH1HU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h 20m
Anti-Histone H2A IgG ELISA
35-H2AHU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h
Anti-Histone H3 IgG ELISA
35-HH3HU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h
Anti-Histone H4 IgG ELISA
35-HH4HU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h
01-EK-IFNB
20–500 titer units
See Protocol
20 µL
Serum
4h 30m
Anti-Inositol-GM ELISA
35-INOHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-Insulin IgG ELISA
35-INAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
27-GD35
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
27-GD126
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-IFN ß Binding Antibodies ELISA
Anti-Intrinsic Factor IgG ELISA Anti-Intrinsic Factor IgG ELISA (Recombinant)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
13-FAJO200 *
See Protocol
See Protocol
100 µL
Plasma, Serum
2h
Anti-Jo-1 ELISA
35-JO1HU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 30m
Anti-LC1 IgG ELISA
35-LC1HU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 30m
Anti-LKM-1 IgG ELISA
35-LKMHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 5m
Anti-M2 IgG ELISA
35-M2GHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
01-EK-MAG ^
1,000–70,000 titer units
See Protocol
2 µL
Serum
4h 30m
27-GD02
3.1–100 U/mL
3.1 u/mL
20 µL
Serum
1h 10m
13-CAP-MPO-110 *
10–320 U
See Protocol
5 µL
Serum
2h
Anti-Ovalbumin IgA ELISA
27-GD40
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Ovalbumin IgG ELISA
27-GD41
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
20-OVAHU-E01
6–100 U/mL
6 U/mL
5 µL
Serum
2h 30m
Anti-PhosphatidylSerine-IgG/IgM ELISA
35-SERHU-E01
3–300 U/mL
1 U/mL
10 µL
Plasma, Serum
1h
Anti-Phospholipid-8 IgG/IgM ELISA
35-P8PHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
Anti-Phospholipid8Pro-A ELISA
35-8PAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
Anti-Phospholipid8S-A ELISA
35-8SAHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
Anti-PR3 ANCA ELISA
27-GD03
6.3–100 U/mL
0.5 U/mL
100 µL
Plasma, Serum
1h
Anti-Prothrombin Factor II IgG ELISA
27-GD76
10–200 U/mL
10 U/mL
10 µL
Plasma
1h 10m
Anti-Prothrombin IgA ELISA
35-PTAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-Prothrombin IgM ELISA
35-PTMHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-RF IgA ELISA
27-GD24
25–400 U/mL
3 U/mL
10 µL
Plasma, Serum
1h
Anti-RF IgG ELISA
27-GD37
40–400 U/mL
3 U/mL
10 µL
Plasma, Serum
1h
Anti-RF IgM ELISA
27-GD23
25–400 U/mL
3 U/mL
10 µL
Plasma, Serum
1h
Anti-RF Screen ELISA
27-GD06
25–500 U/mL
3 U/mL
10 µL
Plasma, Serum
1h 10m
35-RIBHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
27-GD82
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
50m
Anti-Jo-1 DIASTAT® ELISA
Anti-MAG Autoantibodies ELISA Anti-MPO ELISA Anti-MPO-ANCA IgG Capture ELISA
Anti-Ovarian Antibody ELISA
Anti-Ribosomal P IgG ELISA Anti-Rubella IgG ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
69
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Anti-Scl 70 IgG ELISA
35-SCIHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-SGPG Autoantibodies ELISA
01-EK-SGPG ^
Cut-off: See Protocol
See Protocol
2 µL
Serum
4h 30m
Anti-SLA IgG ELISA
35-SLAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 35m
Anti-Sm IgG ELISA
35-SMIHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-Sm/RNP-C IgG ELISA
35-SNRHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-Soya IgA ELISA
27-GD44
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-Soya IgG ELISA
27-GD45
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
20-ASAHU-E01
62–500 U/mL
62 U/mL
10 µL
Plasma, Serum
1h 30m
Anti-ß 2 Glycoprotein IgA ELISA
27-GD30
See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-ß 2 Glycoprotein IgG ELISA
27-GD31
5–100 U/mL
5 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-ß 2 Glycoprotein IgM ELISA
27-GD32
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-ß 2 Glycoprotein Screen ELISA
35-B2SHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-ß Lactoglobulin IgA ELISA
27-GD38
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-ß Lactoglobulin IgG ELISA
27-GD39
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Anti-SS-A/Ro IgG ELISA
35-SSAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-SS-A-52 IgG ELISA
35-S52HU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-SS-A-60 IgG ELISA
35-S60HU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-SS-B-La IgG ELISA
35-SSBHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
27-GD12
50–400 U/mL
1.1 U/mL
10 µL
Plasma, Serum
50m
35-SDAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
35-SSSHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-ss-DNA IgG ELISA
35-SDGHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-ss-DNA IgM ELISA
35-SDMHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Antithrombin IgA ELISA
35-TBAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Antithrombin IgG/IgM ELISA
35-TBGHU-E01
3–300 U/mL
1 U/mL
100 µL
Serum
1h
Anti-Sperm Antibody ELISA
70
Anti-ss-DNA ELISA Anti-ss-DNA IgA ELISA Anti-ss-DNA IgA/IgG/IgM Screen ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Anti-Tissue Transglutaminase IgA ELISA
27-GD70
5–100 U/mL
5 U/mL
10 µL
Plasma, Serum
1h 10m
Anti-TNF α Inhibitor ELISA (Antibody Against ENBREL®)
30-9653
Cut-off: See Protocol
See Protocol
100 µL
Serum
Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652
Cut-off: See Protocol
See Protocol
100 µL
EDTA Plasma, Serum
Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Remicade®)
30-9650
Cut-off: See Protocol
See Protocol
100 µL
Plasma, Serum
Overnight
Anti-tTg-A ELISA
35-TGAHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 30m
Anti-tTg-G ELISA
35-TGGHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-U1-70 ELISA
35-U17HU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-α Fodrin IgA ELISA
35-AFOHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Anti-α Fodrin IgG ELISA
35-AFGHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
APRIL ELISA
30-9411
15.6–1,000 ng/mL
15.6 ng/mL
100 µL
Cell Culture, Plasma
6h 20m
APRIL ELISA
61-APRHU-E01
0.78–50 ng/mL
0.4 ng/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
ASCA IgG ELISA
27-GD78
Cut-off: See Protocol
See Protocol
10 µL
Plasma, Serum
1h 10m
Aspergillus IgG Antibody ELISA
27-GD29
12.5–100 U/mL
0.17 U/mL
100 µL
Serum
1h 10m
BAFF ELISA
30-9410
2–128 ng/mL
0.95 ng/mL
50 µL
Cell Culture, Serum
5h 50 m
Bcl-2 ELISA
61-BCLHU-E01
0.50–32 ng/mL
0.5 ng/mL
20 µL
Plasma, Serum, Tissue Culture
3h 10m
50-714-01
Cut-off: See Protocol
See Protocol
See Protocol
Stool
2h 15m
20-BPGHU-E01 *
See Protocol
See Protocol
10 µL
Serum
1h 45m
C. Trachomatis IFA
50-580-01
See Protocol
See Protocol
10 µL
Serum
1h
C4a RIA
51-RK-519
40–1,300 ng/mL
40 ng/mL
450 µL
Plasma
1h
20-C5AHU-E01
0.1–10 µg/L
0.02 µg/L
50 µL
Plasma
35m
01-DS-CAL25
Cut-off: See Protocol
See Protocol
See Protocol
Stool
10m
01-EK-CAL ^ †
10–600 µg/g or 30–1,800 µg/g
10 µg/g
50 mg
Stool
1h 15m
Blastocystis Antigen ELISA Bordetella Pertussis IgG ELISA
C5a ELISA Calprotectin CALcheck Blue™ Dipstick (25 tests) Calprotectin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
†
Pending FDA Clearance
71
Immunology CCPlus® Immunoscan Measurement of anti-cyclic citrullinated peptide (CCP)
The FDA registered CCPlus® Immunoscan assay provides
antibodies has become the method of choice for accurate
sensitive and semi-quantitative determination of IgG
diagnosis of rheumatoid arthritis (RA). A diagnostic value
antibodies to CCP in human sera. The assay is used to
for the measurement of anti-CCP antibodies has been
detect antibodies in a single serum specimen and is as
found in relation to joint involvement and radiological
sensitive as the rheumatoid factor and CCP3 tests but with
damage on early RA. Anti-CCP antibodies have a high
higher clinical specificity.6
positive predictive value and can be detected years before the development of clinical symptoms.1-6
72
Sensitivity at stratified specificity (%) for available RA diagnostic markers6
Total # Patients (RA/Controls)
Stratified Specificity (%)
CCPlus® Immunoscan
CCP3
MCV
RF
100/102
98.5%
73
67
62
17
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Calprotectin ELISA (2x96 Wells)
01-EK-CAL-02 ^
10–600 µg/g or 30–1,800 µg/g
10 µg/g
50 mg
Stool
1h 15m
Calprotectin Quantum Blue® High Range Rapid Test
01-LF-CHR25 ^
100–1,800 µg/g
100 µg/g
80 mg
Stool
15m
Calprotectin Quantum Blue® Rapid Test
01-LF-CAL25 ^
30–300 µg/g
10 µg/g
80 mg
Stool
12m
Cancer Antigen 125 ELISA
25-125HU-E01
15–400 U/mL
15 U/mL
100 µL
Serum
1h 50m
Cancer Antigen 15-3 ELISA
25-153HU-E01
15–240 U/mL
5 U/mL
20 µL
Serum
3h 20m
Cancer Antigen 19-9 ELISA
25-199HU-E01
15–240 U/mL
5 U/mL
100 µL
Serum
3h 20m
72-OCFM7-CA50
0.4–180 U/mL
0.4 U/mL
50 µL
Plasma, Serum
4h
Cancer Antigen 50 RIA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
1 Rantapää-Dahlqvist S, de Jong BA, Berglin E, et al. Antibodies against cyclic
5 Pruijn GJ, Wiik A, van Venrooij WJ. The use of citrullinated peptides and
citrullinated peptide and IgA rheumatoid factor predict the development of
proteins for the diagnosis of rheumatoid arthritis. Arthritis Res Ther. 2010;
rheumatoid arthritis. Arthritis Rheum. Oct 2003; Vol 48 No 10: 2741-2749.
Vol 12 No 1: 203.
2 van Venrooij WJ, van Beers JJ, Pruijn GJ. Anti-CCP antibodies: the past, the
6 Bizzaro N, Tonutti E, Tozzoli R, Villalta D. Analytical and diagnostic
present and the future. Nat Rev Rheumatol. Jun 2011; Vol 7 No 7: 391-398
characteristics of 11 2nd- and 3rd- generation immunoenzymatic methods
3 Svärd A, Kastbom A, Söderlin MK, et al. A comparison between IgG- and
for the detection of antibodies to citrullinated proteins. Clin Chem. Aug
IgA-class antibodies to cyclic citrullinated peptides and to modified
2007; Vol 53 No 8: 1527-1533.
citrullinated vimentin in early rheumatoid arthritis and very early arthritis. J Rheumatology. Jul 2011; Vol 38 No 7: 1265-1272. 4 Aletaha D, Neogi T, Silman AJ, Et al. 2010 Rheumatiod arthritis classification
73
criteria: a American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. Sep 2010; Vol 69 No 9: 1580-1588.
View CCPlus® Immunoscan assay 13-RA-96PLUS on page 73
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
20-724HU-L01
0.14–100 U/mL
0.14 I/mL
10 µL
Plasma, Serum
1h 30m
Cardiolipin IgG/IgM ELISA
35-CAGHU-E01
3–300 GPL/mL
1 GPl/mL
10 µL
Serum
1h
Caspase-8 ELISA
61-CA8HU-E01
0.16–10 ng/mL
0.10 ng/mL
50 µL
Cell Culture, Serum, Tissue Culture
3h
Caspase-9 ELISA
61-CA9HU-E01
1.6–100 ng/mL
0.4 ng/mL
50 µL
Cell Culture, Serum, Tissue Culture
3h 10m
Cathepsin L ELISA
61-CALHU-E01
3.1–50 ng/mL
1.7 ng/mL
50 µL
Cell Culture, Serum
3h 10m
CCPlus Immunoscan® (Anti-CCP ELISA)
13-RA-96PLUS *
25–3,200 U/mL
See Protocol
10 µL
Serum
2h
61-153HU-E01
1.6–100 ng/mL
0.5 ng/mL
50 µL
Cell Culture, Serum
3h 10m
25-CEAHU-E01
3–120 ng/mL
3 ng/mL
50 µL
Serum
1h 20m
Cancer Antigen 72-4 LIA
CD153 ELISA CEA ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology C-Reactive Protein CRP is released as a part of the acute-phase innate system
persists. Because the half-life of this marker is constant, CRP
response which aims to neutralize the inflammatory agent
levels can be used to study the severity of the precipitating
and to promote the healing of the injured tissue. During the
cause of inflammation. ALPCO has immunoassays available
acute-phase response, CRP levels can increase by up to a
for testing CRP levels in plasma and serum from canine,
1000-fold and levels remain high as long as the damage
equine, feline, human, mouse, porcine, rabbit and rat.
View CRP assays on page 75
Description
74
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
35-CELHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h 30m
04-BI-5000
See Protocol
See Protocol
200 µL
Cell Culture
2h
22-CHM-E102
25–600 pg/mL
0.005 pg/mL
10 µL
Plasma, Serum
2h 30m
Chlamydia IgA IFA
50-513-01
See Protocol
See Protocol
10 µL
Serum
1h
Chlamydia IgG IFA
50-511-01
See Protocol
See Protocol
10 µL
Serum
1h
Chlamydia IgM IFA
50-512-01
See Protocol
See Protocol
5 µL
Serum
1h
30-6910
20–1,000 ng/mL
20 ng/mL
100 mg
Stool
2h 30m
01-EK-CIC *
1–50 µg Eq/mL
0.6 µg Eq/mL
20 µL
Serum
2h
48-CINRT-E01
12.5–800 pg/mL
12.5 pg/mL
25 µL
EDTA Plasma, Heparin Plasma, Serum
2h 30m
Complement Factor 3 Canine ELISA
41-CO3CA-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h
Complement Factor 3 Guinea Pig ELISA
41-CO3GP-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
30m
Complement Factor 3 Mouse ELISA
41-CO3MS-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
50m
Complement Factor 3 Rat ELISA
41-CO3RT-E01
12.5–800 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
50m
13-COMPL-300
Cut-off: See Protocol
See Protocol
20 µL
Serum
1h
13-COMPL-AP330
Cut-off: See Protocol
See Protocol
5 µL
Serum
2h
CeliCheck ELISA (Tissue Transglutaminase IgA/IgG ELISA) Cell Proliferation & Toxicity Assay (EZ4U Assay) Chemerin ELISA
Chymotrypsin ELISA CIC ELISA (C1q) CINC-1 Rat ELISA
Complement Functional Screen Total ELISA Complement System Alternative Pathway ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Complement System Classical Pathway ELISA
13-COMPL-CP310
Cut-off: See Protocol
See Protocol
5 µL
Serum
2h
Complement System MBL Pathway ELISA
13-COMPL-MP320
Cut-off: See Protocol
See Protocol
5 µL
Serum
2h
CPA IgA ELISA
27-GD121
6.25–100 µmol/L
6.25 U/mL
10 µL
Plasma, Serum
1h
CPA IgG ELISA
27-GD110
6.25–100 µmol/L
6.25 U/mL
10 µg
Plasma, Serum
1h
CPA IgM ELISA
27-GD120
0–100 U/mL
6.25 U/mL
10 µL
Plasma, Serum
1h
C-Reactive Protein Porcine ELISA
41-CRPPO-E01
6.25–200 ng/mL
5 ng/mL
5 µL
Serum
25m
CREB ELISA (pS133)
62-CREHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
Cripto-1 ELISA
20-CRIHU-E01
50–800 pg/mL
8.4 pg/mL
50 µL
Serum
3h 50m
35-CROHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
41-CRPCA-E01
2.125–200 ng/mL
5 ng/mL
5 µL
Plasma, Serum
25m
30-9710s
1.9–150 ng/mL
0.124 ng/mL
10 µL
Plasma, Serum, Stool, Urine
2h 15m
CRP Equine ELISA
41-CRPEQ-E01
10–320 ng/mL
10 ng/mL
5 µL
Plasma, Serum
1h 15m
CRP Feline ELISA
41-CRPFE-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 15m
CRP Mouse ELISA
41-CRPMS-E01
0.39–25 ng/mL
0.39 ng/mL
5 µL
Plasma, Serum
25m
CRP Rabbit ELISA
41-CRPRB-E01
6.25–200 ng/mL
5 ng/mL
2 µL
Plasma, Serum
25m
CRP Rat ELISA
41-CRPRT-E01
6.25–200 ng/mL
5 ng/mL
5 µL
Plasma, Serum
25m
20-CTGHU-E01
1–500 ng/mL
3.24 ng/mL
25 µL
Serum
3h 45m
1h 10m
Crohns Check ELISA (Anti-Saccharomyces Cerevisiae IgA/IgG ELISA) CRP Canine ELISA
CRP ELISA
CTGF ELISA
75
Cu/ZnSOD ELISA
61-CUZHU-E01
0.08–5 ng/mL
0.04 ng/mL
10 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
CYFRA LIA (21-1)
20-CYFHU-L01
3–50 ng/mL
0.03 ng/mL
50 µL
Heparin Plasma, Serum
30m
Cytochrome C ELISA
61-CYCHU-E01
0.08–5 ng/mL
0.05 ng/mL
100 µL
Tissue Culture
3h 10m
Dengue NS1 ELISA
65-DENHU-E01
See Protocol
See Protocol
50 µL
Serum
1h 51m
DIASTAT® ANA ELISA
13-FANA200 *
See Protocol
See Protocol
10 µL
EDTA Plasma, Serum
2h
DIASTAT® MPO ANCA ELISA
13-FMPO200 *
0–100 U/mL
See Protocol
100 µL
Plasma, Serum
2h
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
45-EGFHU-E01
3.9–250 pg/mL
1 pg/mL
100 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum, Urine
4h
30-7110
3–24 fmol/mL
0.4 fmol/mL
200 µL
Tissue Culture
Overnight
ENA-6Pro ELISA
35-E6PHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
ENA-6S ELISA
35-E6SHU-E01
10–100 U/mL
1 U/mL
10 µL
Serum
1h
Eotaxin Mouse ELISA
61-EOTMS-E01
31.3–2,000 pg/mL
3.6 pg/mL
50 µL
Cell Culture, Serum
3h 10m
ERK1/2 ELISA (pT202/ Y204/pT185/Y187)
62-ERKHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 35m
FGF-21 ELISA
62-FGFHU-E01
30–1,920 pg/mL
10.4 pg/mL
100 µL
Cell Culture, Plasma, Serum
2h 35m
FGF-21 Mouse ELISA
62-FGFMS-E01
31.2–2,000 pg/mL
10.1 pg/mL
100 µL
Cell Culture, Plasma, Serum
2h 35m
GAD ELISA
21-GADHU-E01
0.6–2.99 U/mL
See Protocol
10 µL
Serum
2h 30m
Galectin-3 ELISA
61-GALHU-E01
0.39–25 ng/mL
0.12 ng/mL
50 µL
Cell Culture, EDTA Plasma, Serum
3h 10m
01-EK-GCO
Cut-off: See Protocol
See Protocol
30 µL
Serum
4h 30m
GanglioCombi® Light Anti-Ganglioside ELISA
01-EK-GCL-GM
Cut-off: See Protocol
See Protocol
30 µL
Serum
4h 30m
G-CSF ELISA
45-GCSHU-E01
39–2,500 pg/mL
20 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
3h
GM-CSF ELISA
61-GMCHU-E01
7.8–500 pg/mL
2.9 pg/mL
50 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
GM-CSF Mouse ELISA
61-GMCMS-E01
3.9–250 pg/mL
2 pg/mL
50 µL
Cell Culture, Serum
3h
GM-CSF Rat ELISA
61-GMCRT-E01
7.8–500 pg/mL
3.5 pg/mL
50 µL
Cell Culture, Serum
3h 10m
Granzyme A ELISA
61-GRAHU-E01
0.8–600 pg/mL
0.4 pg/mL
50 µL
Cell Culture, Plasma, Serum
2h
Granzyme B ELISA
61-GRBHU-E01
0.66–480 pg/mL
0.2 pg/mL
50 µL
Cell Culture, Serum
2h
GSK3α/ß (pS21/pS9) and Active ß-Catenin ELISA
62-GCAHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
GSK3α/ß ELISA (pS21/pS9)
62-GSKHU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
HAHA ELISA
43-HAHHU-E01
1–27 µg/mL
1 µg/mL
25 µL
Plasma, Serum
1h 50m
HAMA ELISA
43-HAMHU-E01
40–1,500 ng/mL
2 ng/mL
25 µL
Serum
1h 50m
41-HAPBO-E01
15.6–1,000 ng/mL
15.6 ng/mL
5 µL
Plasma, Serum
40m
EGF ELISA
EGF Receptor ELISA
76
GanglioCombi® AntiGanglioside Auto Antibody ELISA
Haptoglobin Bovine ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Haptoglobin Canine ELISA
41-HAPCA-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin ELISA
41-HAPHU-E01
3.125–200 ng/mL
3.125 ng/mL
100 µL
Plasma, Serum
35m
Haptoglobin Equine ELISA
41-HAPEQ-E01
18.75–600 ng/mL
18.75 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Feline ELISA
41-HAPFE-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Mouse ELISA
41-HAPMS-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
Haptoglobin Porcine ELISA
41-HAPPO-E01
25–400 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin Rabbit ELISA
41-HAPRB-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
Haptoglobin Rat ELISA
41-HAPRT-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
HBe/Anti-HBe ELISA
68-4BNE3
See Protocol
See Protocol
50 µL
Plasma, Serum
2h 30m
HBsAg ELISA
68-4SGE3
See Protocol
See Protocol
50 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 50m
13-COMP-200
10–80 ng/mL
10 ng/mL
5 µL
Serum
Overnight
61-HERHU-E01
0.16–10 ng/mL
0.06 ng/mL
100 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
20-HSMHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 45m
Histamine ELISA
17-HISHU-E01
0.3–30 ng/mL
See Protocol
25 µL
Plasma, Urine
Overnight
Histamine ELISA (Cell Culture)
17-HISCC-E01
0.5–50 ng/mL
0.2 ng/mL
20 µL
Cell Culture, Urine
1h
17-HISRT-E01-RES
0.3–30 ng/mL
0.2 ng/mL
10 µL
EDTA Plasma
Overnight
IFN-gamma ELISA
61-IFGHU-E01
1.6–100 pg/mL
0.99 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IFN-gamma Monkey ELISA
45-IFNMK-E01
15.6–1,000 pg/mL
4 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h
IFN-gamma Mouse ELISA
61-IFGMS-E01
15.6–1,000 pg/mL
5.3 pg/mL
50 µL
Cell Culture, Serum
3h 10m
61-IFGRT-E01
31.3–2,000 pg/mL
9.9 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IgA Chicken ELISA
41-IGACH-E01
12.5–400 ng/mL
12.5 ng/mL
100 µL
Plasma, Serum
50m
IgA ELISA
41-IGAHU-E01
12.5–800 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 10m
IgA Mouse ELISA
41-IGAMS-E01
12.5–3,025 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 40m
hCOMP ELISA
HER-2 ELISA
Herpes Simplex Virus 1 IgM ELISA
Histamine Research ELISA
IFN-gamma Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
77
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
41-IGART-E01
31.25–1,000 pg/mL
31.25 ng/mL
5 µL
Plasma, Serum
1h 10m
41-IGDHU-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
IgE Canine ELISA
41-IGECA-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
IgE Equine ELISA
41-IGEEQ-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 45m
IgE Feline ELISA
41-IGEFE-E01
12.5–400 ng/mL
12.5 ng/mL
10 µL
Plasma, Serum
2h 15m
IgE Mouse ELISA
41-IGEMS-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
41-IGERT-E01
1–32 ng/mL
1 ng/mL
10 µL
Plasma, Serum
2h 15m
25-IGEHU-E01 *
10–800 IU/mL
5 IU/mL
20 µL
Serum
1h 20m
IgG Canine ELISA
41-IGGCA-E01
25–800 ng/mL
25 ng/mL
5 µL
Plasma, Serum
45m
IgG Mouse ELISA
41-IGGMS-E01
9.375–600 ng/mL
9.375 ng/mL
5 µL
Plasma, Serum
1h 45m
41-IGGRT-E01
25–800 ng/mL
25 ng/mL
5 µL
Plasma, Serum
1h 45m
30-6510
0.32–5 mg/L
0.14 mg/L
10 µL
Cell Culture, Plasma, Serum
2h 5m
IgG1 Mouse ELISA
41-IG1MS-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
IgG2A Mouse ELISA
41-I2AMS-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 30m
IgG2B Mouse ELISA
41-I2BMS-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
IgG3 Mouse ELISA
41-IG3MS-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 30m
IgM Canine ELISA
41-IGMCA-E01
25–800 ng/mL
25 ng/mL
5 µL
Plasma, Serum
1h 15m
IgM Chicken ELISA
41-IGMCH-E01
3.125–200 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 15m
IgM ELISA
41-IGMHU-E01
7.8–500 ng/mL
7.8 ng/mL
5 µL
Plasma, Serum
1h 45m
IgM Mouse ELISA
41-IGMMS-E01
25–800 ng/mL
25 ng/mL
5 µL
Plasma, Serum
1h 45m
IgM Rat ELISA
41-IGMRT-E01
31.25–1,000 ng/mL
31.25 ng/mL
5 µL
Plasma, Serum
1h 15m
IgY Chicken ELISA
41-IGYCH-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
IL-10 ELISA
61-I10HU-E01
3.15–200 pg/mL
1 pg/mL
50 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
IL-10 Monkey ELISA
61-I10MK-E01
3.9–250 U/mL
1.3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-10 Mouse ELISA
61-I10MS-E01
15.6–1,000 pg/mL
5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
IgA Rat ELISA IgD ELISA
IgE Rat ELISA IgE Total ELISA
78 IgG Rat ELISA IgG Total ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
45-I10PO-E01
7.8–500 pg/mL
3 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h
61-I10RT-E01
15.6–1,000 pg/mL
1.5 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-10 Ultrasensitive ELISA
45-I10HUU-E01
0.78–50 pg/mL
0.2 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
IL-10 Ultrasensitive ELISA
45-I10HUU-E05
0.78–50 pg/mL
0.2 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
IL-12 ELISA (p70)
61-P12HU-E01
3.1–200 pg/mL
2.1 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-12 Monkey ELISA (p70)
61-P12MK-E01
3.9–250 U/mL
2.6 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-12 Mouse ELISA (p70)
61-P12MS-E01
15.6–1,000 pg/mL
10 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-12/IL-23 ELISA (p40)
61-ILPHU-E01
31.3–2,000 pg/mL
< 10 pg/mL
50 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
4h 10m
2h 10m
IL-10 Porcine ELISA
IL-10 Rat ELISA
79
IL-13 ELISA
61-I13HU-E01
1.6–100 pg/mL
0.7 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
IL-13 Mouse ELISA
61-I13MS-E01
7.8–500 pg/mL
2.8 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 10m
IL-15/IL-15R Mouse ELISA
61-I15MS-E01
6.3–400 pg/mL
2 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
3h 30m
IL-17A ELISA
61-ILAHU-E01
1.6–100 pg/mL
0.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
IL-17A Mouse ELISA
61-ILAMS-E01
7.8–500 pg/mL
1.6 pg/mL
50 µL
Cell Culture, Serum
3h 10m
61-ILART-E01
1.6–100 pg/mL
1 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-17AF ELISA
61-IAFHU-E01
31.3–2,000 pg/mL
8.8 pg/mL
50 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 30m
IL-17AF Mouse ELISA
61-IAFMS-E01
3.9–250 pg/mL
3.3 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
3h 30m
IL-17F ELISA
61-ILFHU-E01
31.3–2,000 pg/mL
15.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-17F Mouse ELISA
61-ILFMS-E01
62.5–4,000 pg/mL
10 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
4h 30m
IL-18 Porcine ELISA
61-I18PO-E01
39.1–2,500 pg/mL
23 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-17A Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
61-1RAHU-E01
109–7,000 pg/mL
30 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
61-I1BRT-E01
31.3–2,000 pg/mL
4 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-1α ELISA
61-I1AHU-E01
1.6–100 pg/mL
1.1 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-1α Mouse ELISA
61-I1AMS-E01
7.8–500 pg/mL
4 pg/mL
50 µL
Cell Culture, Serum
3h 10m
61-I1ART-E01
15.6–1,000 pg/mL
4 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-2 ELISA
61-IL2HU-E01
18.8–1,200 pg/mL
9.9 pg/mL
100 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
IL-2 Monkey ELISA
61-IL2MK-E01
20–1,250 U/mL
10 U/mL
100 µL
Cell Culture, Serum
3h 10m
IL-2 Mouse ELISA
61-IL2MS-E01
15.6–1,000 pg/mL
5.3 pg/mL
50 µL
Cell Culture, Serum
3h 10m
61-IL2RT-E01
62.5–2,000 pg/mL
11 pg/mL
50 µL
Cell Culture, Serum
4h 10m
IL-21 ELISA
61-I21HU-E01
78–5,000 pg/mL
20 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
IL-22 ELISA
61-I22HU-E01
31.3–2,000 pg/mL
5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 10m
IL-22 Mouse ELISA
61-I22MS-E01
7.8–500 pg/mL
5 pg/mL
50 µL
Cell Culture, Citrate Plasma, Serum
3h 30m
IL-23 ELISA
61-I23HU-E01
15.6–2,000 pg/mL
4 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h
IL-23 Mouse ELISA
61-I23MS-E01
31.3–2,000 pg/mL
16 pg/mL
50 µL
Cell Culture, Citrate Plasma, Serum
4h 10m
IL-27 ELISA
61-I27HU-E01
62.5–4,000 pg/mL
9.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
IL-29 ELISA (IFN-lambda1)
61-IFLHU-E01
15.6–1,000 pg/mL
2 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-3 ELISA
45-IL3HU-E01
7.8–500 pg/mL
1 pg/mL
100 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Plasma, Serum
4h
IL-31 ELISA
61-I31HU-E01
7.8–500 pg/mL
1 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
IL-1RA ELISA
IL-1ß Rat ELISA
IL-1α Rat ELISA
80
IL-2 Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
IL-33 ELISA
61-I33HU-E01
7.8–500 pg/mL
0.2 pg/mL
50 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
4h 30m
IL-4 ELISA
61-IL4HU-E01
7.8–500 pg/mL
1.3 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h 10m
IL-4 Mouse ELISA
61-IL4MS-E01
3.9–250 pg/mL
2 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-4 Porcine ELISA
45-IL4PO-E01
15.6–1,000 pg/mL
2 pg/mL
50 µL
Cell Culture, Serum
3h
IL-4 Rat ELISA
45-IL4RT-E01
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, Serum
3h
IL-4 Rat ELISA
61-IL4RT-E01
1.6–100 pg/mL
0.2 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-5 ELISA
61-IL5HU-E01
7.8–500 pg/mL
1.5 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-5 Mouse ELISA
61-IL5MS-E01
7.8–500 pg/mL
3.3 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-6 ELISA
45-IL6HU-E01
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA
45-IL6HU-E05
7.8–500 pg/mL
2 pg/mL
100 µL
Cell Culture, EDTA Plasma, Serum
3h
IL-6 Monkey ELISA
61-IL6MK-E01
1.9–120 U/mL
1.3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-6 Mouse ELISA
61-IL6MS-E01
31.3–2,000 pg/mL
6.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
61-IL6RT-E01
31–2,000 pg/mL
12 pg/mL
50 µL
Cell Culture, Serum
3h 10m
IL-8 ELISA
61-IL8HU-E01
15.6–1,000 pg/mL
2 pg/mL
50 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-8 Monkey ELISA
61-IL8MK-E01
19.5–1,250 U/mL
3 U/mL
50 µL
Cell Culture, Serum
3h 10m
IL-8 Porcine ELISA
45-IL8PO-E01
31.2–2,000 pg/mL
10 pg/mL
50 µL
Cell Culture, Serum
4h
45-IL8HUU-E01
0.39–25 pg/mL
0.1 pg/mL
100 µL
Cell Culture, Plasma, Serum, Urine
4h
61-IL9HU-E01
3.1–200 pg/mL
0.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
21-IAAHU-E01
Cut-off: See Protocol
See Protocol
25 µL
Serum
Overnight
IP-10 Mouse ELISA
61-IP1MS-E01
7.8–500 pg/mL
6.5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 10m
Islet Cell Antibody ELISA
21-ICAHU-E01
Cut-off: See Protocol
See Protocol
25 µL
Serum
2h 30m
Japanese Encephalitis IgG ELISA
65-JEGHU-E01
See Protocol
See Protocol
4 µL
Serum
2h 16m
IL-6 Rat ELISA
IL-8 Ultrasensitive ELISA
IL-9 ELISA
Insulin Autoantibody ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
81
Health Canada Licensed
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Japanese Encephalitis IgM ELISA
65-JEMHU-E01
See Protocol
See Protocol
4 µL
Serum
3h 16m
Kappa ELISA
41-KAPHU-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h
L1-CAM ELISA
20-LCAHU-E01
8.75–280 ng/mL
0.1 ng/mL
50 µL
Serum
1h 45m
Lactoferrin ELISA
41-LACHU-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Milk, Plasma, Serum
1h 15m
Lambda ELISA
41-LAMHU-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h
30-6600
6.25–400 µM
6.25 µM
500 µL
Plasma, Serum, Urine
1h 30m
61-LIFHU-E01
3.15–200 pg/mL
0.7 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h
MCP-1 ELISA
61-MCPHU-E01
15.6–1,000 pg/mL
2.3 pg/mL
20 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
MCP-1 Mouse ELISA
61-MCPMS-E01
15.6–1,000 pg/mL
2.2 pg/mL
50 µL
Cell Culture, Serum
3h 10m
MCP-1 Rat ELISA
45-MCPRT-E01
11.7–750 pg/mL
8 pg/mL
50 µL
Cell Culture, Plasma, Serum
2h 30m
20-MEGHU-E01 *
See Protocol
See Protocol
10 µL
Serum
1h 45m
MMP-13 ELISA
61-M13HU-E01
0.31–20 ng/mL
0.18 ng/mL
50 µL
Cell Culture, Serum
3h 10m
MMP-3 ELISA
48-MP3HU-E01
12.5–800 ng/mL
0.01 ng/mL
40 µL
Serum
2h
MMP-9 ELISA
61-MP9HU-E01
0.23–15 ng/mL
0.05 ng/mL
10 µL
Cell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
30-6630
1.2–100 ng/mL
1.6 ng/mL
100 mg
Stool, Urine
2h 20m
MPO ELISA (Serum and Plasma)
30-6631A
1.9–30 ng/mL
1.08 ng/mL
10 µL
Plasma, Serum
3h 20m
MPO Mouse ELISA
41-MPOMS-E01
0.31–20 ng/mL
0.31 ng/mL
5 µL
Plasma, Serum
1h 30m
MRP 8/14 ELISA
01-EK-MRP8/14
0.4–24 µg/mL
0.4 µg/mL
10 µL
Plasma, Serum
1h 15m
Mycobacterium Tuberculosis IgG ELISA
65-TBGHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Mycobacterium Tuberculosis IgM ELISA
65-TBMHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Neopterin ELISA
14-HD-99.1
2–250 nmol/L
2 nmol/L
50 µL
Plasma, Serum, Urine
2h 30m
Neopterin RIA
14-HD-97.1
3–729 nmol/L
0.8 nmol/L
20 µL
Biological Fluids
1h
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
L-Citrulline ELISA Leukemia Inhbitory Factor ELISA
82
Measles IgG ELISA
MPO ELISA
NGAL Canine ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Neopterin
Representative Standard Curve from 14-HD-99.1
Neopterin serves as a marker of activation of the adaptive immune system. It is synthesized by macrophages
1.8 1.6
upon stimulation with the cytokine interferon-gamma Optical Density (OD)
1.4
and is indicative of a pro-inflammatory immune status. Measurement of circulating neopterin concentrations provides information about cellular immune activation in
1.2 1.0 0.8 0.6 0.4
humans under the control of T helper cells type 1. ALPCO
0.2
offers both an ELISA and an RIA for the measurement of
0.0 2
20
200
Neopterin [nmol/l]
Neopterin in plasma, serum and urine.
83 View neopterin assays 14-HD-99.1 and 14-HD-97.1 on page 82
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
NGAL Canine ELISA
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA
54-036
10–1,000 pg/mL
4 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA
54-042
10–500 pg/mL
0.75 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA
54-044
10–400 pg/mL
1 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA
54-037
0.2–20 ng/mL
0.008 ng/mL
10 µL
EDTA Plasma, Plasma, Serum, Urine
1h
NGAL Rat ELISA
54-046
4–400 pg/mL
0.5 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
Nucleo-h IgG ELISA
35-NUCHU-E01
3–300 U/mL
1 U/mL
10 µL
Serum
1h
Orientia Tsutsugamushi IgG ELISA
65-OTGHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Orientia Tsutsugamushi IgM ELISA
65-OTMHU-E01
See Protocol
See Protocol
4 µL
Serum
1h 16m
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Osteopontin ELISA
41-OPNHU-E01
0.31–20 ng/mL
0.05 ng/mL
10 µL
Heparin Plasma, Urine
3h
Ovotransferrin Chicken ELISA
41-OVOCH-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h
p38 α ELISA (pT180/Y182)
62-P38HU-E01
See Protocol
See Protocol
100 µL
Cell Culture, Tissue Culture
4h 30m
p53 ELISA
61-P53HU-E01
0.78–50 U/mL
0.33 U/mL
50 µL
Cell Culture, Serum
3h 10m
PAI-1 ELISA
61-PAIHU-E01
78–5,000 pg/mL
29 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
PAP Complex ELISA
20-PCOHU-E02
50–5,000 µg/L
10 µg/L
50 µL
Plasma
45m
PAPP-A ELISA
20-PAPHU-E01
1–30 µg/mL
0.133 µg/mL
10 µL
Plasma, Serum
1h 15m
55-PAPHUU-E01
11.25–450 ng/mL
0.023 ng/mL
100 µL
Serum
45m
Pertussis IgG ELISA
13-PERT-PTG2 *
Cut-off: See Protocol
See Protocol
See Protocol
Serum
2h
Platelet Derived Growth Factor ELISA
61-PDGHU-E01
31.3–2,000 pg/mL
4.6 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
PMN Elastase Ultrasensitive ELISA
30-6840
0.37–10 ng/mL
0.12 ng/mL
100 mg, 100 µL
Plasma, Seminal Fluids, Serum, Stool
3h 15m
PMN-Elastase ELISA
61-PMNHU-E01
0.16–10 ng/mL
1.98 ng/mL
100 µL
Cell Culture, Plasma, Serum
2h
30-2601
See Protocol
See Protocol
1 mL
Urine
See Protocol
PR3-ANCA Capture ELISA
13-CAP-PR3 *
Cut-off: See Protocol
See Protocol
10 µL
Serum
2h
Progranulin ELISA
22-PRG-E103
0.75–25 ng/mL
0.018 ng/mL
10 µL
Plasma, Serum
2h
PSA NCAM ELISA
67-ABC0027B
0.25–16 ng/mL
0.25 ng/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
Overnight
PSA Total ELISA
25-PSAHU-E01
2–120 ng/mL
1 ng/mL
50 µL
Serum
2h 20m
PSA Total LIA
11-PSAHU-L01
0.1–100 ng/mL
0.082 ng/mL
50 µL
Serum
1h 30m
45-RANHU-E01
31.2–2,000 pg/mL
3 pg/mL
50 µL
Cell Culture, Serum
2h
04-BI-RC4D
See Protocol
See Protocol
See Protocol
See Protocol
See Protocol
s90K/Mac-2BP ELISA
61-MACHU-E01
12.5–200 ng/mL
0.92 ng/mL
100 µL
Cell Culture, Plasma, Serum
1h
sAPO-1/Fas ELISA
61-APOHU-E01
15.6–1,000 pg/mL
13.2 pg/mL
10 µL
Cell Culture, Serum
2h 10m
sCD134 ELISA (OX40)
61-134HU-E01
78–5,000 pg/mL
1.8 pg/mL
25 µL
Cell Culture, Serum
3h 10m
sCD137 ELISA
61-137HU-E01
0.78–50 ng/mL
0.2 ng/mL
50 µL
Cell Culture, Serum
3h 10m
PAPP-A Ultrasensitive ELISA
84
Porphyrins HPLC
RANTES/CCL5 ELISA RC4d Antibody
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
RC4d Within the adaptive system’s cascade of events is the classical complement pathway, consisting of a number of small proteins in the blood including, but not limited to C1, C2, C3 and C4. Until recently, it was thought that the humoral pathway was most often associated with an acute transplant rejection. However, there are visible features of humoral rejection seen in more chronic rejection settings, especially in patients with renal allografts, one of which is the deposition of C4d in the capillary bed of renal allografts.
Paraffin embedded tissue sections
C4d is a split product of C4. Because C4d covalently binds to adjacent membrane surfaces it can be easily detected using conventional methods. As such, immunostaining with an antibody targeting C4d is an important method that can be used to identify humoral-graft rejection.1 85 1 Troxwell, ML et al. Comparison of C4d immunostaining methods in renal allograft biopsies. Clinical J American Society Nephrology. May 2006; Vol 1 No 3: 583-591.
View RC4d assay 04-BI-RC4D on page 84
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
sCD152/CTLA-4 ELISA
61-CTLHU-E01
0.16–10 ng/mL
0.13 ng/mL
10 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD23 ELISA
61-C23HU-E01
12.5–400 U/mL
6.8 U/mL
100 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD26 ELISA
61-C26HU-E01
15.6–500 ng/mL
7.3 ng/mL
20 µL
Cell Culture, Serum
4h 10m
sCD28 ELISA
61-C28HU-E01
0.78–50 ng/mL
0.18 ng/mL
50 µL
Cell Culture, Serum
3h 10m
sCD30 ELISA
61-C30HU-E01
1.6–100 ng/mL
0.3 ng/mL
25 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD40 ELISA
61-C40HU-E01
7.8–500 pg/mL
1.3 pg/mL
50 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD40L ELISA
61-40LHU-E01
0.16–10 ng/mL
0.06 ng/mL
20 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sCD40L Mouse ELISA
61-40LMS-E01
0.31–20 ng/mL
0.14 ng/mL
50 µL
Cell Culture, Serum
3h 10m
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Immunology Description
sCD44std ELISA
86
Catalog #
61-C44HU-E01
Range
0.13–4 ng/mL
Sensitivity
0.02 ng/mL
Sample Size
Sample Type
Incubation
20 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
3h 10m
sCD44var ELISA (v5)
61-445HU-E01
0.31–10 ng/mL
0.14 ng/mL
20 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
sCD44var ELISA (v6)
61-446HU-E01
0.32–10 ng/mL
0.05 ng/mL
20 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD-8 ELISA
61-CD8HU-E01
31–2,000 U/mL
7 U/mL
50 µL
Citrate Plasma, Serum
3h 10m
Sclero-Profile IgG ELISA
35-SCLHU-E01
Cut-off: See Protocol
See Protocol
10 µL
Serum
1h
Secretory IgA ELISA
30-8870
22.2–600 ng/mL
13.4 ng/mL
100 mg, 10 µL
Saliva, Stool
2h 10m
Secretory IgA1 ELISA
30-6863
3.3–100 U
3.3 U
100 mg
Stool
2h 15m
Secretory IgA2 ELISA
30-6864
3.3–100 U
3.3 U
100 mg
Stool
2h 15m
50-FA261-01M
10–100 BU/mL
See Protocol
10 µL
Serum
2h 15m
50-B261-01M
10–100 BU/mL
See Protocol
10 µL
Serum
2h 15m
50-FA262-01M
10–100 BU/mL
See Protocol
10 µL
Serum
2h 15m
50-B262-01M
10–100 BU/mL
See Protocol
10 µL
Serum
2h 15m
Serum Amyloid A ELISA
41-SAAHU-E01
0.157–10 ng/mL
0.157 ng/mL
10 µL
Plasma, Serum
1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E01
31.25–2,000 ng/mL
31.25 ng/mL
5 µL
Serum
1h 40m
Serum Amyloid ß Auto-Antibody ELISA
20-SABHU-E01
1–120 RTU
See Protocol
20 µL
Serum
2h 30m
sE-selectin ELISA
61-ESEHU-E01
0.8–50 ng/mL
0.3 ng/mL
20 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sE-selectin Monkey ELISA
61-ESEMK-E01
1.9–60 U/mL
0.4 U/mL
20 µL
Cell Culture, Serum
2h 10m
sFas Ligand ELISA
61-FALHU-E01
0.16–10 ng/mL
0.07 ng/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sICAM-1 ELISA
61-IC1HU-E01
6.25–100 ng/mL
2.2 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1h 10m
sICAM-1 Monkey ELISA
61-IC1MK-E01
6.3–100 U/mL
1.1 U/mL
10 µL
Cell Culture, Serum
1h 10m
SeroMP lgG ELISA SeroMP lgG ELISA (2 Plate) SeroMP lgM ELISA SeroMP lgM ELISA (2 Plate)
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description sICAM-1 Ultrasensitive ELISA
Catalog #
61-IC1HUU-E01
Range
0.63–10 ng/mL
Sensitivity
0.33 ng/mL
Sample Size
Sample Type
Incubation
100 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Plasma, Serum, Urine
2h 10m
1h
sICAM-2 ELISA
61-IC2HU-E01
0.75–24 U/mL
0.30 U/mL
100 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine, Whole Blood
sICAM-3 ELISA
61-IC3HU-E01
0.78–50 ng/mL
0.38 ng/mL
20 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
2h 10m
sIL-2R ELISA
61-I2RHU-E01
0.31–20 ng/mL
0.27 ng/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sIL-6R ELISA
61-I6RHU-E01
0.08–5 ng/mL
0.01 ng/mL
20 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
2h 10m
sL-selectin ELISA
61-LSEHU-E01
0.4–25 ng/mL
0.2 ng/mL
50 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sPECAM-1 ELISA
61-PECHU-E01
0.47–30 ng/mL
0.06 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
sPECAM-1 Monkey ELISA
61-PECMK-E01
0.48–30 U/mL
0.06 U/mL
10 µL
Cell Culture, Serum
3h 10m
sP-selectin ELISA
61-PSEHU-E01
0.63–40 ng/mL
0.20 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 30m
sP-selectin Monkey ELISA
61-PSEMK-E01
0.8–50 U/mL
1.3 U/mL
10 µL
Cell Culture, Serum
2h 30m
sPSGL-1 ELISA
61-PSGHU-E01
1.6–50 U/mL
1 U/mL
100 µL
Cell Culture, Serum
3h 10m
ß Defensin 2 ELISA
30-6500
0.1–3 ng/mL
0.077 ng/mL
100 mg
Stool
3h 30m
ß-4 Thymosin ELISA
30-9520
0.16–10 µg/mL
0.1 µg/mL
50 µL
Serum, Tissue Culture
2h 20m
61-TN6HU-E01
0.08–5 ng/mL
0.05 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
2h 10m
sTNF-R ELISA (60kDa)
sTNF-R ELISA (80kDa)
61-TN8HU-E01
0.16–10 ng/mL
0.10 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
sTNF-R I Monkey ELISA
61-TR1MK-E01
0.09–6 U/mL
0.06 U/mL
10 µL
Cell Culture, Serum
2h 10m
sVAP-1 ELISA
61-VAPHU-E01
31.3–2,000 pg/mL
19 pg/mL
10 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
87
Immunology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
sVCAM-1 ELISA
61-VCAHU-E01
3.15–100 ng/mL
0.6 ng/mL
100 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sVE-cadherin ELISA
61-VECHU-E01
0.16–10 ng/mL
0.1 ng/mL
20 µL
Cell Culture, Heparin Plasma, Serum
3h 10m
sVE-cadherin Monkey ELISA
61-VECMK-E01
0.19–12.5 U/mL
0.10 U/mL
20 µL
Cell Culture, Serum
3h 10m
sVEGF-R1/FLT-1 ELISA
61-VGRHU-E01
0.16–10 ng/mL
0.03 ng/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
TGF ß-1 ELISA
20-TGF1HU-E01
19–600 pg/mL
1.9 pg/mL
10 µL
Cell Culture, Plasma, Serum
6h 45m
TGF ß-2 ELISA
20-TGF2HU-E01
31.25–1,000 pg/mL
10 pg/mL
10 µL
Cell Culture, Plasma, Serum
5h 30m
61-TB1MS-E01
31.3–2,000 pg/mL
9 pg/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
5h 30m
61-TB1RT-E01
31.3–2,000 pg/mL
8 pg/mL
100 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
5h 30m
61-TB2HU-E01
31–1,000 pg/mL
6.6 pg/mL
100 µL
Cell Culture, Serum
5h 35m
41-THIRT-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Serum
2h 10m
30-9810
0.03–16 ng/mL
0.03 ng/mL
50 µL
Serum
Overnight
61-TIEHU-E01
0.16–10 ng/mL
0.03 ng/mL
10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
Overnight
TIMP-1 ELISA
61-TIMHU-E01
39–2,500 pg/mL
10 pg/mL
20 µL
Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
TNF-ß ELISA
61-TNBHU-E01
15.6–1,000 pg/mL
4.6 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h 10m
TNF-α ELISA
45-TNFHU-E05
15–1,500 pg/mL
1.7 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
TNF-α ELISA
45-TNFHU-E01
15.6–1,500 pg/mL
1.7 pg/mL
100 µL
Cell Culture, Plasma, Serum
4h
TNF-α Monkey ELISA
61-TNAMK-E01
28.1–1,800 U/mL
6 U/mL
50 µL
Cell Culture, Serum
3h 10m
TNF-α Mouse ELISA
61-TNFMS-E01
15.6–1,000 pg/mL
3 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
45-TNFPO-E01.1
23.4–1,500 pg/mL
4 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
5h
61-TNART-E01
39.1–2,500 pg/mL
11 pg/mL
50 µL
Cell Culture, Serum
3h 10m
TGF-ß1 Mouse ELISA
88 TGF-ß1 Rat ELISA
TGF-ß-2 ELISA Thiostatin Rat ELISA Thymulin ELISA
TIE-2 ELISA
TNF-α Porcine ELISA
TNF-α Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
TNF-α Ultrasensitive ELISA
45-TNFHUU-E01
0.5–32 pg/mL
0.09 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h
TNF-α Ultrasensitive ELISA
45-TNFHUU-E05
0.5–32 pg/mL
0.09 pg/mL
50 µL
Cell Culture, Plasma, Serum
3h
TNF-α-Blocker Monitoring ELISA (Humira®)
30-9657
0.625–20 µg/mL
0.4 µg/L
5 µL
Serum
5h 20m
TNF-α-Blocker Monitoring ELISA (Remicade®)
30-9655
0.53–45 µg/mL
0.4 µg/L
5 µL
Serum
5h 20m
ToxoPlasma IgG Ab ELISA
27-GD80
Cut-off: See Protocol
See Protocol
5 µL
Plasma, Serum
See Protocol
TRAIL ELISA
61-TRAHU-E01
15.6–1,000 pg/mL
5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h
VEGF ELISA
45-VEGHU-E01
23–1,500 pg/mL
5 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Serum
4h
VEGF-A ELISA
61-VGAHU-E01
15.6–1,000 pg/mL
7.9 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
VEGF-A Mouse ELISA
61-VGAMS-E01
62.5–4,000 pg/mL
20 pg/mL
50 µL
Cell Culture, EDTA Plasma, Serum
4h 30m
61-VGCRT-E01
47–3,000 pg/mL
27 pg/mL
50 µL
Cell Culture, Heparin Plasma, Serum
3h 30m
VEGF-R2/KDR ELISA
61-KDRHU-E01
78–5,000 pg/mL
7 pg/mL
50 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
VEGF-R3/FLT-4 ELISA
61-FLTHU-E01
0.6–40 ng/mL
0.03 ng/mL
50 µL
Cell Culture, Citrate Plasma, Serum
3h 30m
Visceral Leishmaniasis ELISA
65-VILHU-E01
See Protocol
See Protocol
10 µL
Serum
1h 16m
West Nile Virus IgG ELISA
65-WNGHU-E01
See Protocol
See Protocol
4 µL
Serum
2h 15m
West Nile Virus IgM ELISA
65-WNMHU-E01 *
See Protocol
See Protocol
4 µL
Serum
3h 16m
Zonulin ELISA
30-5600
0–1,000 ng/mL
0.6 ng/mL
250 µL
Stool
3h 10m
Zonulin ELISA (Serum)
30-5601
See Protocol
0.6 ng/mL
See Protocol
Serum
3h 10m
VEGF-C Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
89
Health Canada Licensed
Neurobiology
90
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Neurobiology Neurobiology brings together many disciplines including biochemistry, molecular biology, anatomy, physiology and medicine to study the cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. ALPCO offers a number of relevant biomarker assays and formats which can be used for the investigation of neurological function, diseases and disorders of sensory information processing. 91
Peripheral Neuropathy
anti-ganglioside titers may aid in the differential
Ganglioside, MAG and SGPG ELISAs can aid in the
determination of peripheral neuropathies.1
differentiation of neurological disorders including Guillian BarrĂŠ, Miller Fisher, and chronic inflammatory
Neurological disorders can be caused by a variety
demyelinating polyneuropathy.
of systemic diseases, toxic exposures, medications, infections, and hereditary disorders.2 Studies have
Gangliosides
linked the presence of high anti-ganglioside titers
Gangliosides are glycosphingolipids containing sialic
to several neuropathies including Guillain-BarrĂŠ
acid residues which are particularly abundant in
Syndrome (GBS), Miller-Fisher Syndrome (MFS), Acute
membrane components of the peripheral nervous
Motor Axonal Neuropathy (AMAN), Multifocal Motor
system. Variances in ganglioside structure give rise
Neuropathy (MMN), and Chronic Ataxic Neuropathy,
to numerous antibody targets where production
Opthalmoplegia, IgM Paraprotein, Agglutinin and
of certain anti-ganglioside autoantibodies can be
Disialosyl Antibodies (CANOMAD). Additionally,
associated with specific neurological conditions.
correlations have been drawn between the severity of
Research has shown quantitative detection of these
the disorder and the isotype detected. IgG antibodies
Neurobiology have been strongly associated with acute conditions
other neuropathy target antigens (i.e. gangliosides,
while IgM antibodies tend to present in chronic diseases.
SGPG). Research has shown detection of anti-MAG IgM
Many of these neurological disorders exhibit similar
autoantibodies, especially at high titers, is associated with
symptoms involving sensory loss and distal pain,
sensory-motor demyelinating peripheral neuropathies
numbness, tingling and weakness, making them difficult
and IgM gammopathy.4
to dissociate. An increasing level of research indicates immunological tests for ganglioside antibodies plays
SGPG
an important role in the diagnosis and management of
Antibodies recognizing MAG react with a carbohydrate
neuromuscular diseases.3
determinant that is also present on Sulfate-3-glucuronyl paragloboside (SGPG). While MAG is restricted to
92
MAG
the periaxonal Schwann cell membranes, SGPG has a
The myelin-associated glycoprotein(MAG) is a
wider distribution with presence in both Schwann cell
transmembrane glycoprotein localized in periaxonal
and neuronal membranes including myelin, axolemma,
Schwann cells and ogliodendroglial membranes of myelin
and neural endothelial cells. Sensory demyelinating
sheaths. IgM antibodies in most neuropathy cases react
neuropathies typically exhibit anti-MAG and anti-SGPG
to the oligosaccharides (HNK-1 epitope) of glycolipids
activity but the presence of anti-SGPG antibodies may be
and glycoproteins that are concentrated in the peripheral
considered more characteristic of a non-demyelinating
nerves. This epitope is also shared by a number of
motor neuropathy.5
1 Gorenjac, Maksimiljan. Clinical and Diagnostic Role of Ganglioside Antibody Testing. The Journal of The International Federation of Clinical Chemistry and Laboratory Medicine. 2000; Vol15 No 3. <http://www.ifcc.org/ifccfiles/docs/150309200414.pdf> 2 Azhary, Hend. et al. Peripheral Neuropathy: Differential Diagnosis and Management. American Family Physician. Apr 2010; Vol 81: 887-892. 3 Winner, John. Antibodies and clinical neurological syndromes. The Biomedical Scientist. Jul 2006; 622-624. 4 Czaplinski, A. and Steck, A.J. Antibody testing in peripheral neuropathies. A critical approach. Schweizer Archiv f端r Neurologie und Psychiatry. Jul 2002; Vol 153 No 7: 301-7. 5 Neuromuscular Clinical Laboratory. Anti-SGPG antibodies. 2012. <http://neuromuscular.wustl.edu/over/labdis.html#sgpg>
Anti-Myelin Associated Glycoprotein (MAG) ELISA The MAG assay utilizes a highly purified MAG antigen from human brain and studies have shown this
Anti-MAG ELISA detected 49 out of 68 total positives for demyelinating polyneuropathy and IgM gammopathy. 70 60 50 40 30 20 10 0
77%
Bühlmann ELISA
ELISA to be more sensitive than
54%
44% WB-a
WB-b
western blot.6
6 Kuijf, M.L., et al. Detection of anti-MAG antibodies in polyneuropathy associated with IgM monoclonal gammopathy. Neurology. Sept 2009. Vol 73 No 9: 688-
93
95.
View the anti-MAG assay 01-EK-MAG on page 93
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
11-ANDHU-E01
0.25–50 ng/mL
0.1 ng/mL
50 µL
Serum
45m
17-5HIHU-E01
0.5–50 mg/L
0.17 mg/L
50 µL
Urine
1h 15m
6-Sulfatoxymelatonin ELISA
01-EK-M6S
0.8–40 ng/mL
0.14 ng/mL
10 µL
Urine
4h
α-MSH RIA
13-RB 303
4.7–150 pmol/L
3 pmol/L
100 µL
Cerebrospinal Fluid, Plasma
Overnight
21-ACTHU-E01 *
5–500 pg/mL
0.46 pg/mL
200 µL
Plasma
5h
01-EK-GM1-GM ^
Cut-off: See Protocol
See Protocol
20 µL
Serum
4h 30m
01-EK-IFNB
20–500 titer units
See Protocol
20 µL
Serum
4h 30m
Anti-MAG Autoantibodies ELISA
01-EK-MAG ^
1,000–70,000 titer units
See Protocol
2 µL
Serum
4h 30m
Anti-SGPG Autoantibodies ELISA
01-EK-SGPG ^
Cut-off: See Protocol
See Protocol
2 µL
Serum
4h 30m
17-BCTHU-E02.1
See Protocol
See Protocol
300 µL, 10 µL
Plasma, Urine
4h
5a-Androstane-3a, 17b-diol Glucuronide ELISA 5-HIAA ELISA
ACTH ELISA Anti-GM1 Autoantibodies ELISA Anti-IFN ß Binding Antibodies ELISA
Bi-CAT (Epinephrine & Norepinephrine) ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Neurobiology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
17-BCTHU-E02-RES
See Protocol
See Protocol
See Protocol
Biological Fluids
Overnight
17-BCTHU-R200
See Protocol
See Protocol
300 µL, 10 µL
Plasma, Urine
4h
17-BINHU-E02-UFST
See Protocol
See Protocol
25 µL
Urine
1h 45m
Bradykinin ELISA
48-BRAHU-E01
7.2–5,000 pg/well
7.2 pg/mL
10 µL
Plasma, Urine
Overnight
cAMP ELISA
55-AMPHU-E02
0.05–10 pMol/mL
0.1 pMol/mL
50 µL
Plasma, Urine
3h 30m
cGMP ELISA
55-GMPHU-E02
0.05–10 pMol/mL
0.1 pMol/mL
50 µL
Cell Culture, Plasma, Urine
3h 30m
CGRP ELISA
32-5481
7.81–1,000 pg/mL
5 pg/mL
100 µL
Plasma, Serum
Overnight
CGRP Rat ELISA
32-5482
3.91–500 pg/mL
1 pg/mL
100 µL
Plasma, Serum, Tissue Culture
Overnight
43-CHRHU-E01.2
31–830 ng/mL
5 ng/mL
50 µL
EDTA Plasma
2h 20m
13-RB 321
0.156–5 nmol/L
0.04 nmol/L
50 µL
Plasma
Overnight
CRF ELISA
20-CRFHU-E01
0.01–1,000 ng/mL
0.01 ng/mL
50 µL
Plasma, Serum
4h
CRF-HS Mouse/Rat ELISA
48-CRFMS-E01
0.078–2.5 ng/mL
0.078 ng/mL
50 µL
Plasma, Tissue Culture
8h 30m
17-DOPHU-E01.1
10–2,000 ng/mL
4.5 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
17-DOPHU-E01-RES
0.5–80 ng/mL
See Protocol
See Protocol
Biological Fluids
Overnight
17-DOPHU-R100
10–2,000 ng/mL
4.5 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
17-EPIHU-E01.1
1–200 ng/mL
0.3 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
17-EPIHU-E01-RES
0.5–80 ng/mL
See Protocol
See Protocol
Biological Fluids
Overnight
Epinephrine RIA
17-EPIHU-R100
1–200 ng/mL
0.3 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
GABA ELISA
17-GABHU-E01
15–1,500 ng/mL
7.5 ng/mL
300 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
Overnight
GanglioCombi® AntiGanglioside Auto Antibody ELISA
01-EK-GCO
Cut-off: See Protocol
See Protocol
30 µL
Serum
4h 30m
GanglioCombi® AntiGanglioside Auto Antibody ELISA (Dual Plate lgG and lgM)
01-EK-GCO-GM
Cut-off: See Protocol
See Protocol
30 µL
Serum
4h 30m
01-EK-GCL-GM
Cut-off: See Protocol
See Protocol
30 µL
Serum
4h 30m
32-5188
0.3–40 ng/mL
0.5 ng/mL
50 µL
Cell Culture, Plasma
4h
Bi-CAT (Epinephrine & Norepinephrine) Research ELISA Bi-CAT (Epinephrine & Norepinephrine) RIA Bi-Neph (Metanephrine & Normetanephrine) ELISA
94 Chromogranin A ELISA Chromogranin A RIA
Dopamine ELISA Dopamine Research ELISA Dopamine RIA Epinephrine ELISA Epinephrine Research ELISA
GanglioCombi® Light Anti-Ganglioside ELISA GFAP ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
GanglioCombi® ELISAs The GanglioCombi® ELISA assays
Flexible ELISA formats for
Proprietary method for homogenous
provide a flexible format for IgM
differentiation of neurological
plate coating
and IgG detection of the most
disorders
relevant gangliosides. A proprietary
• Minimal inter/intra lot and
• Mixed IgG/IgM conjugate
method for homogenous plate
technician variation
for screening
coating minimizes inter/intra lot
• No non-specific binding
• Individual IgG/IgM conjugates
and technician variation, offering a
for differential determination
reliable and cost effective method for autoimmune ganglioside testing.
Ability to compare results among all Gangliocombi® assays
Simple, reliable, cost effective
• Identical set of calibrator and
method for routine use
controls for all kits 95
• Quantitative • 30 µL sample size • Results in 4 hours 30 minutes
Ganglioside Detection Conjugate
asialoGM1
GM1
GM2
GD1a
GD1b
GQ1b
01-EK-GCO
ü
ü
ü
ü
ü
ü
50:50 Mixed IgG/IgM
01-EK-GCO-GM
ü
ü
ü
ü
ü
ü
Individual IgG and IgM
ü
ü
Individual IgG and IgM
01-EK-GCL-GM
ü
01-EK-GM1-GM^
ü
Individual IgG and IgM
Neurobiology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
GHB Enzymatic Assay
01-KK-GHB
5–250 mg/L
1.5 mg/L
8 µL
Serum, Urine
8m
17-GLUHU-E01
0.6–60 µg/mL
0.3 µg/ml
100 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
Overnight
Melatonin Direct Saliva RIA
01-RK-DSM2
0.5–50 pg/mL
0.3 pg/mL
400 µL
Saliva
Overnight
Melatonin ELISA (Direct Saliva)
01-EK-DSM.1
0.5–25 pg/mL
0.29 pg/mL
200 µL
Saliva
Overnight
Melatonin RIA
01-RK-MEL2
0.5–50 pg/mL
0.2 pg/mL
1 mL
Plasma, Serum
Overnight
Metanephrine ELISA (Plasma)
17-METHU-E01-FST
30–3,000 pg/mL
10 pg/mL
250 µL
Plasma
Overnight
17-NORHU-E01.1
5–1,000 ng/mL
1.5 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
17-NORHU-E01-RES
0.2–32 ng/mL
See Protocol
See Protocol
Biological Fluids
Overnight
Norepinephrine RIA
17-NORHU-R100
5–1,000 ng/mL
1.5 ng/mL
300 µL, 10 µL
Plasma, Urine
4h
NPY RIA
13-NPYHU-R100
9.4–300 pmol/L
6 pmol/L
200 µL
Plasma, Serum
48h
43-NSEHU-E01
5–178 ng/mL
1.2 ng/mL
10 µL
Serum
1h 10m
67-ABC0027B
0.25–16 ng/mL
0.25 ng/mL
100 µL
Cell Culture, Plasma, Serum, Tissue Culture
Overnight
48-PYYHU-E01.1
0.082–20 ng/mL
0.082 ng/mL
50 µL
Plasma, Serum
Overnight
48-PYYRT-E01.1
0.15–12.5 ng/mL
0.31 ng/mL
25 µL
EDTA Plasma, Plasma, Serum
Overnight
48-CBPHU-E01
0.078–5 ng/mL
0.078 ng/mL
20 µL
Plasma
5h 30m
Serotonin ELISA
17-SERHU-E01-FST
15–2,500 ng/mL
5 ng/mL
25 µL
Cerebrospinal Fluid, Plasma, Platelets, Serum, Urine
1h 15m
Serotonin Research ELISA
17-SERHU-E01-RES
0.015–2.5 ng/mL
See Protocol
See Protocol
Biological Fluids
Overnight
17-SERHU-R100
15–2,500 ng/mL
0.3 ng/mL
25 µL, 100 µL
Cerebrospinal Fluid, Plasma, Platelets, Serum, Urine
2h 15m
Serum Amyloid A ELISA
41-SAAHU-E01
0.157–10 ng/mL
0.157 ng/mL
10 µL
Plasma, Serum
1h
Serum Amyloid P Mouse ELISA
41-SAPMS-E01
6.25–200 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
2h 10m
41-SAPRT-E01
2.5–160 ng/mL
2.5 ng/mL
5 µL
Plasma, Serum
25m
20-SABHU-E01
1–120 RTU
See Protocol
20 µL
Serum
2h 30m
13-RB 301
15.6–500 pmol/L
3 pmol/L
3 mL
Plasma
Overnight
17-TCTHU-E03.1
See Protocol
See Protocol
300 µL, 10 µL
Plasma, Urine
4h
Glutamate ELISA
Norepinephrine ELISA Norepinephrine Research ELISA
96
NSE ELISA PSA NCAM ELISA PYY ELISA PYY Mouse/Rat ELISA S100 ß ELISA
Serotonin RIA
Serum Amyloid P Rat ELISA Serum Amyloid ß Auto-Antibody ELISA ß Endorphin RIA Tri-CAT (Epinephrine, Norepinephrine, Dopamine) ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Melatonin Melatonin is a key modulator of seasonal and circadian
Offered exclusively from ALPCO, the Bühlmann portfolio
biorhythms. The synthesis and secretion of melatonin is
of melatonin assays utilizes the Kennaway G280 antibody
regulated by a circadian clock in the hypothalamus and is
and provides the most sensitive detection of melatonin
synchronized by the diurnal light-dark cycle.
across multiple biological samples.
View melatonin assays 01-RK-DSM2, 01-EK-DSM.1 and 01-RK-MEL2 on page 96
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
17-TCTHU-E03-RES
See Protocol
See Protocol
See Protocol
Biological Fluids
Overnight
17-TCTHU-R300
See Protocol
See Protocol
300 µL, 10 µL
Plasma, Urine
4h
17-TRPHU-E01
2.5–250 µg/mL
1.2 µg/mL
20 µL
Plasma, Serum, Urine
Overnight
Urocortin 2 Mouse ELISA
48-UR2MS-E01
0.81–200 ng/mL
0.82 ng/mL
20 µL
Plasma, Serum
Overnight
Urocortin 3 Mouse/ Rat ELISA
48-UROMS-E01
0.41–100 ng/mL
0.137 ng/mL
25 µL
Plasma, Serum
Overnight
Tri-CAT (Epinephrine, Norepinephrine, Dopamine) Research ELISA Tri-CAT (Epinephrine, Norepinephrine, Dopamine) RIA Tryptophan ELISA
97
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Toxicology
98
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Toxicology Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in preclinical models and 40% for Phase I clinical trials.1 Now more than ever, labs engaged in compound, drug and device screening and development are chartered with performing a comprehensive survey of potential toxicological side effects as part of their routine practice. 99
ALPCO offers a wide range of preclinical species-specific assays that provide a means for scientists to achieve their goals in this endeavor.
Hepatotoxicity DILI can be hepatocellular or choleostatic in nature, but
transaminases as a safety marker in rat models, and may
because viral hepatitis, environmental toxins, or other
offer the potential to more accurately assess compound
diseases present the same pathogenic findings as DILI,
toxicity by supplementing current screening methods.5
even biopsy is not conclusive.2 Assessment of DILI has primarily relied on the release of enzymes from necrotic
Nephrotoxicity
cells, functional indicators of hepatic activity or increases in
Until recently, drug-induced acute kidney injury
circulating bilirubin.3 Drug-induced liver injury has become
(DIAKI) has been determined by measurement of
the single most common cause for removal of an approved
serum creatinine and blood urea nitrogen, both of
drug from market,4 so there continues to be a need for more
which become elevated after damage has occurred.
specific and sensitive markers of hepatocellular damage.
The advent of novel markers, such as NGAL and Ď&#x20AC;-GST,
One such biomarker, Îą-GST, has been shown to outperform
are allowing researchers to detect DIAKI earlier and
Toxicology identify the site-specific injury.6,7 The work by the Critical
Trastuzumab, carry high risks.10 Cardiotoxicity may be
Path Institute’s Predictive Safety Testing Consortium has
as mild as electrocardiographic changes or arrhythmias,
identified and proposed seven new nonclinicalbiomarkers,
but can progress to myocardial infraction and even
KIM-1, Albumin, Total Protein, β2-microglobulin, Cystatin
cardiomyopathy. Biomarkers of cardiomyocyte injury,
C, Clusterin and Trefoil Factor-3, for consideration by the
like Troponin I, ANP, BNP and CK-MB, may be helpful for
FDA, EMA and PDMA in the drug review process.
identification of risks associated with these agents.11
Cardiotoxicity
1 Suter L, Babiss LE, and Wheeldon EB. Toxicogenomics in predictive toxicology in
Cardiotoxicity can occur due to exposure to heavy metals, recreational drugs or pharmaceutical compounds. It
100
drug development. Chem Biology. Feb 2004; Vol 11 No 2: 161-171. 2 U.S. Department of Health and Human Services. Food and Drug Administration.
is a common side effect of chemotherapeutic agents,
Center for Drug Evaluation and Research. Guidance for Industry, Drug-
such as those in the Anthracycline class.9 Even the
Induced Liver Injury: Premarketing Clinical Evaluation. Washington: Office of
newer biologic anticancer therapeutics, such as
Communications, Division of Drug Information. Jul 2009.
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
30-2112
5.1–200 pg/mL
4.8 pg/mL
500 µL
Plasma, Serum
Overnight
30-KM1100
See Protocol
See Protocol
500 µL
Plasma, Serum
1h 8m
α-1-Acid Glycoprotein Chicken ELISA
41-AGPCH-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
α-1-Acid Glycoprotein ELISA
41-AGPHU-E01
5–320 ng/mL
5 ng/mL
5 µL
Plasma, Serum
1h 15m
α-1-Acid Glycoprotein Rat ELISA
41-AGPRT-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 20m
α-1-Microglobulin ELISA
30-6710
0.019–1.5 mg/L
0.006 mg/L
10 µL
Plasma, Serum, Urine
4h 45m
α-2-Macroglobulin ELISA
30-6610
0.07–5 mg/L
0.05 mg/L
10 µL
Plasma, Serum, Stool
2h 15m
α-2-Macroglobulin Rabbit ELISA
41-A2MRB-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
α-2-Macroglobulin Rat ELISA
41-A2MRT-E01
6.25–400 ng/mL
6.24 ng/mL
5 µL
Plasma, Serum
1h 20m
α-GST ELISA
69-AGTHU-E01
2.5–80 μg/L
1.9 μg/L
50 µL
Plasma, Serum, Urine
2h
1,25 (OH)2 Vitamin D ELISA 1,25 (OH)2 Vitamin D Extraction Kit
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
3 Lee WM and Senior JR. Recognizing drug-induced liver injury: current problems,
8 Dieterle F, et al. Renal biomarker qualification submission: a dialog between the
possible solutions. Toxicol Pathology. 2005; Vol 33 No 1: 155-164.
FDA-EMEA and Predictive Safety Testing Consortium. Nat Biotechnology. May
4 Temple RJ and Himmel MH. Safety of newly approved drugs: implications for
2010; Vol 28 No 5:455-462.
prescribing. JAMA. May 2002; Vol 287 No 17: 2273–2275.
9 Ewer MS and Ewer SM. Cardiotoxicity of anticancer treatments: what the
5 Clarke H, et al. Alpha-glutathione s-transferase (alpha-GST) release, an early
cardiologist needs to know. Nat Rev Cardiology. Oct 2010; Vol 7 No 10: 564-
indicator of carbon tetrachloride hepatotoxicity in the rat. Hum Exp Toxicology.
575.
Mar 1997; Vol 16 No 3: 154-157.
10 Cardinale D, et al. Trastuzumab-Induced Cardiotoxicity: Clinical and Prognostic
6 Mishra J, Ma Q, Prada A, et al. Identification of neutrophil gelatinase-associated
Implications of Troponin I Evaluation. J Clin Oncology. Sep 2010; Vol 25 No 28:
lipocalin as a novel urinary biomarker for ischemic injury. J Am Soc Nephrology.
3910-3916.
Oct 2003; Vol 14 No 10: 2534–2543.
11 Gharib MI and Burnett AK. Chemotherapy-induced cardiotoxicity: current
7 Koyner JL, et al. Urinary Biomarkers in the Clinical Prognosis and Early
practice and prospects of prophylaxis. Eur J Heart Fail. Jun 2002; Vol 4 No 3:
Detection of Acute Kidney Injury. Clin J Am Soc Nephrology. Dec 2010; Vol 5 No
101
235-242.
12: 2154-2165.
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
25-BMGHU-E01 *
0.625–10 µg/mL
0.1 µg/mL
10 µL
Serum
1h 20m
41-MICRT-E01
25–800 ng/mL
25 ng/mL
10 µL
Plasma, Serum
1h 30m
AFP ELISA
25-AFPHU-E01
5–300 ng/mL
2 ng/mL
20 µL
Serum
1h 20m
Albumin Canine ELISA
41-ALBCA-E01
12.5–400 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum
1h 45m
30-6330
12.5–800 µg/L
12.5 µg/L
100 mg, 10 µL
Stool, Urine
2h 20m
Albumin Monkey ELISA
41-ALBMK-E01
12.5–400 ng/mL
12.5 ng/mL
100 µL
Serum, Tissue Culture
1h 40m
Albumin Mouse ELISA
41-ALBMS-E01
7.8–500 ng/mL
5 ng/mL
2 µL
Plasma, Serum, Urine
1h 10m
Albumin Porcine ELISA
41-ALBPO-E01
12.5–400 ng/mL
See Protocol
5 µL
Plasma, Serum, Urine
1h 40m
Albumin Rat ELISA
41-ALBRT-E01
6.25–400 ng/mL
5 ng/mL
5 µL
Plasma, Serum, Urine
1h 10m
01-EK-AM1
1–100 ng/mL
0.22 ng/mL
40 µL
Plasma, Serum, Urine
1h
32-5103
15.6–2,000 pg/mL
15.6 pg/mL
50 µL
Citrate Plasma, EDTA Plasma
Overnight
13-BANI 1
7.8–1,000 pg/mL
3.5 pg/mL
500 µL
Plasma
Overnight
ß-2 Microglobulin ELISA ß-2 Microglobulin Rat ELISA
Albumin ELISA
Amanitin ELISA ANP Rat ELISA ANP RIA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Toxicology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
BNP Fragment ELISA (Nt-proBNP 8-29)
04-BI-20852W
5–1,000 fmol/mL
5 fmol/mL
35 µL
Cell Culture, Plasma, Serum
Overnight
Clusterin Rat ELISA
41-CLURT-E01
12.5–800 ng/mL
12.5 ng/mL
5 µL
Plasma, Serum, Urine
1h 30m
25-CKMHU-E01
7.5–200 ng/mL
7.5 ng/mL
20 µL
Serum
1h 20m
Cystatin C ELISA
41-CYCHU-E01
0.7815–50 ng/mL
0.7815 ng/mL
5 µL
Plasma, Serum
1h
Cystatin C Monkey ELISA
41-CYCMK-E01
0.125–4 ng/mL
See Protocol
5 µL
Plasma, Serum
1h 50m
Cystatin C Mouse ELISA
41-CYCMS-E01
1.25–40 ng/mL
1.25 ng/mL
2 µL
Plasma, Serum
1h 40m
Cystatin C PETIA
01-KK-CYC *
0.4–8 mg/L
0.33 mg/L
2 µL
Plasma, Serum
10m
Cystatin C PETIA
01-KK-CYC-6 *
0.4–8 mg/L
0.33 mg/L
2 µL
Plasma, Serum
10m
Cystatin C Rat ELISA
41-CYCRT-E01
2.63–20 ng/mL
2.63 ng/mL
5 µL
Plasma, Serum
1h 45m
04-BI-20742
0–80 nmol/L
0.2 nmol/L
10 µL
Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
01-KK-GHB
5–250 mg/L
1.5 mg/L
8 µL
Serum, Urine
8m
41-YGTRT-E01
3.12–100 ng/mL
3.12 ng/mL
5 µL
Plasma, Serum, Urine
2h 10m
Haptoglobin Bovine ELISA
41-HAPBO-E01
15.6–1,000 ng/mL
15.6 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin Canine ELISA
41-HAPCA-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin ELISA
41-HAPHU-E01
3.125–200 ng/mL
3.125 ng/mL
100 µL
Plasma, Serum
35m
Haptoglobin Equine ELISA
41-HAPEQ-E01
18.75–600 ng/mL
18.75 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Feline ELISA
41-HAPFE-E01
6.25–400 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 15m
Haptoglobin Mouse ELISA
41-HAPMS-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
Haptoglobin Porcine ELISA
41-HAPPO-E01
25–400 ng/mL
5 ng/mL
5 µL
Plasma, Serum
40m
Haptoglobin Rabbit ELISA
41-HAPRB-E01
6.25–200 ng/mL
6.25 ng/mL
5 µL
Plasma, Serum
1h 30m
Haptoglobin Rat ELISA
41-HAPRT-E01
7.81–125 ng/mL
5 ng/mL
5 µL
Plasma, Serum
35m
KIM-1 ELISA
41-KIMHU-E01
0.156–10 ng/mL
0.156 ng/mL
100 µL
Plasma, Serum, Urine
1h 40m
KIM-1 Mouse ELISA
41-KIMMS-E01
0.078–5 ng/mL
0.078 ng/mL
100 µL
Serum, Urine
2h 40m
KIM-1 Rat ELISA
41-KIMRT-E01
0.156–10 ng/mL
0.156 ng/mL
50 µL
Serum, Urine
3h 15m
L-FABP ELISA
41-LFAHU-E01
1–32 ng/mL
1 ng/mL
50 µL
Plasma, Serum
1h 15m
41-LFART-E01
12.5–400 ng/mL
12.5 ng/mL
20 µL
Plasma, Serum
1h 30m
24-MABHU-E01
0.5–100 µg/mL
0.24 µg/mL
10 µL
Urine
40m
Creatine Kinase ELISA
102
Endostatin ELISA
GHB Enzymatic Assay GST Yb1 Rat ELISA
L-FABP Rat ELISA Microalbumin ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
Myoglobin ELISA
25-MYOHU-E01 *
25–1,000 ng/mL
25 ng/mL
20 µL
Serum
1h 5m
Myoglobin ELISA
24-MYOHU-E01
0–250 ng/mL
6.25 ng/mL
10 µL
Serum, Urine
30m
Myoglobin Mouse ELISA
41-MYOMS-E01
4.69–300 ng/mL
4.69 ng/mL
30 µL
Plasma, Serum
1h 40m
41-MYORT-E01
3.125–200 ng/mL
3.125 ng/mL
75 µL
Serum
1h 25m
73-1290050
0.25–200 U/L
0.25 U/L
10 µL
Plasma, Serum, Urine
15m
73-1085
0.25–200 U/L
0.25 U/L
10 µL
Plasma, Serum, Urine
15m
73-1290100
0.25–200 U/L
0.25 U/L
10 µL
Plasma, Serum, Urine
15m
NAG Spectrophotometric Assay (320)
73-130050
0.16–33 U/L
0.16 U/L
50 µL
Plasma, Serum, Urine
30m
NAG Spectrophotometric Assay (640)
73-130100
0.16–33 U/L
0.16 U/L
50 µL
Plasma, Serum, Urine
30m
NGAL Canine ELISA
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Canine ELISA
54-043
4–400 pg/mL
0.56 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA
54-036
10–1,000 pg/mL
4 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA
54-042
10–500 pg/mL
0.75 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA
54-044
10–400 pg/mL
1 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA
54-037
0.2–20 ng/mL
0.008 ng/mL
10 µL
EDTA Plasma, Plasma, Serum, Urine
1h
NGAL Rat ELISA
54-046
4–400 pg/mL
0.5 pg/mL
10 µL
Cell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
Osteopontin ELISA
41-OPNHU-E01
0.31–20 ng/mL
0.05 ng/mL
10 µL
Heparin Plasma, Urine
3h
Osteopontin Mouse ELISA
41-OPNMS-E01
0.03–2 ng/mL
0.015 ng/mL
5 µL
Plasma
3h
Pi GST ELISA
69-PGTHU-E01
1.25–40 μg/L
1.3 μg/L
125 µL
Urine
2h 15m
30-6331
1.6–100 ng/mL
3 ng/mL
100 mg
Plasma, Serum, Stool
2h 15m
41-PALMS-E01
15.625–500 ng/mL
15.625 ng/mL
5 µL
Plasma, Serum
1h
41-PALRT-E01
15.625–500 ng/mL
15.625 ng/mL
5 µL
Plasma, Serum
1h
Myoglobin Rat ELISA NAG Reagent Set (300) * NAG Reagent Set (5x60) * NAG Reagent Set (600) *
Prealbumin ELISA Prealbumin Mouse ELISA
Prealbumin Rat ELISA
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
103
Toxicology Description
Catalog #
Range
Sensitivity
Sample Size
Sample Type
Incubation
proANP ELISA (1-98)
04-BI-20892
0.63–10 nmol/L
0.05 nmol/L
10 µL
Cell Culture, Plasma, Urine
4h
72-OCFK07-PIIIP
0.1–14 U/mL
0.1 U/mL
20 µL
Plasma, Serum
5h
41-RBPMS-E01
0.625–20 ng/mL
See Protocol
5 µL
Plasma, Serum
1h 10m
RBP4 Rat ELISA
41-RBPRT-E01
6.25–200 ng/mL
See Protocol
5 µL
Plasma, Serum, Urine
1h 30m
Type IV Collagen ELISA (Serum)
69-C4SHU-E01
15.6–1,000 μg/L
15.6 μg/L
20 µL
Serum
1h
Type IV Collagen ELISA (Urinary)
69-C4UHU-E01
0.8–50 μg/L
0.8 µg/L
50 µL
Urine
Overnight
Vitamin D Binding Protein ELISA
30-2314
2.2–60 ng/mL
1.23 ng/mL
10 µL
Plasma, Serum, Urine
2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E01
3.125–100 ng/mL
3.125 ng/mL
5 µL
Plasma, Serum
1h 30m
Procollagen III Peptide RIA RBP4 Mouse ELISA
104
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
^
Health Canada Licensed
105
Immunology Flow Cytometry
106
Products are for Research Use Only unless otherwise noted
â&#x20AC;Ą
Indicates an Analyte Specific Reagent
Flow Cytometry Flow cytometry is a technique used to evaluate single cell properties, including relative size, internal complexity and relative fluorescent intensity. Flow cytometry has applications in a number of fields such as molecular biology, pathology, immunology and medicine. Within the field of medicine, it is frequently used in transplantation, hematology and tumor immunology. ALPCO offers a broad range of unique and affordable flow cytometry solutions that can be used to study any 107
application of interest.
EuroFlow™ Panels and Infinicyt™ Software EuroFlow™ Panels ALPCO provides validated EuroFlow™ 8-color antibody
Two groups of markers are combined in each
panels for immunophenotyping and identification of
8-color tube:
hematological malignancies. The single-tube screening panels and multi-tube classification panels fit into the EuroFlow™ consortium’s algorithm with entries defined by the consortium’s standardized laboratory parameters.1
1
1. Backbone markers to identify distinct cell populations in a sample, and 2. Markers for characterization of specific cell populations
Van Dongen JJM et al. EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia. Sep 2012; Vol 26 No 9: 1908–1975.
Immunology Flow Cytometry In multi-tube panels, the backbone markers are optimally
Infinicyt™
placed at the same fluorochrome position in every tube
Infinicyt™ is a flow cytometry analysis software program
in order to provide identical multidimensional localization
that provides an innovative approach for data integration
of the target cell population(s). The characterization
and multidimensional analysis of flow cytometry data. Its
markers are positioned according to the utility of the
state-of-the-art features make analysis and interpretation
combined markers.
of results easier, faster and more accurate. It is recommended by the EuroFlow™ Consortium.
108
Catalog #
Clone
Isotype
Excitation Laser
71-HCD1A-A
HI149
IgG1
Red
71-HCD1A-PC
HI149
IgG1
Blue
CD2 APC
71-HCD2-A
TP1/31
IgG1
Red
CD2 APC-C750
70-2AC750
LT2
IgG2b
Red
CD2 CF-Blue
71-HCD2-CB
TP1/31
IgG1
Violet
CD2 PerCP
71-HCD2-PC
TP1/31
IgG1
Blue
CD3 APC
71-HCD3-A
33-2A3
IgG2a
Red
CD3 APC
70-3AP6
33-2A3
IgG2a
Red
70-3AC750
UCHT-1
IgG1
Red
CD3 CF-Blue
71-HCD3-CB
UCHT1
IgG1
Violet
CD3 DY-634
71-HCD3-DY
33-2A3
IgG2a
Red
70-3F8
Cris-7
IgG2a
Blue
CD3 OC-515
71-HCD3-OC
33-2A3
IgG2a
Violet
CD3 OC-515
71-HCD3-OC.2
UCHT1
IgG1
Violet
70-3PE5
33-2A3
IgG2a
Blue
71-HCD3-PC
33-2A3
IgG2a
Blue
CD4 APC
71-HCD4-A
HP2/6
IgG2a
Red
CD4 FITC
70-4F5
Edu-2
IgG2a
Blue
Single Color Antibodies CD1a APC CD1a PerCP
CD3 APC-C750
CD3 FITC
CD3 PE CD3 PerCP
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Catalog #
Clone
Isotype
Excitation Laser
71-HCD4-OC
HP2/6
IgG2a
Violet
70-4PBZ ‡
H2P/6
IgG2a
Violet
CD4 PE
71-HCD4-PE
HP2/6
IgG2a
Blue
CD4 PerCP
71-HCD4-PC
HP2/6
IgG2a
Blue
70-4C5 ‡
SK3
IgG1
Blue
71-HCD5-A
33-1C5
IgG2a
Red
CD5 CF-Blue
71-HCD5-CB
33-1C5
IgG2a
Violet
CD5 OC-515
71-HCD5-OC
33-1C5
IgG2a
Violet
CD5 PerCP
71-HCD5-PC
33-1C5
IgG2a
Blue
70-5C ‡
UCHT2
IgG1
Blue
CD6 APC
71-HCD6-A
MAE-1C10
IgG1
Red
CD6 Biotin
71-HCD6-B
MAE-1C10
IgG1
n/a
71-HCD6-CB
MAE-1C10
IgG1
Violet
71-HCD6-F
MAE-1C10
IgG1
Blue
71-HCD6-PE
MAE-1C10
IgG1
Blue
CD7 APC
70-7AP4 ‡
CD7-6B7
IgG2a
Red
CD7 APC
71-HCD7-A
HIT7
IgG1
Red
CD7 Biotin
71-HCD7-B
HIT7
IgG1
n/a
71-HCD7-CB
HIT7
IgG1
Violet
CD7 FITC
71-HCD7-F
HIT7
IgG1
Blue
CD8 APC
71-HCD8-A
143-44
IgG1
Red
35-DSMHU-E01
3 - 300 U/mL
1.0 U/mL
Serum
71-HCD8-A.2
MEM-31
IgG2a
Red
71-HCD8-B
143-44
IgG1
n/a
CD8 CF-Blue
71-HCD8-CB
143-44
IgG1
Violet
CD8 DY-634
71-HCD8-DY
143-44
IgG1
Red
70-8F8 ‡
UCHT-4
IgG2a
Blue
71-HCD8-OC
143-44
IgG1
Violet
Single Color Antibodies CD4 OC-515 CD4 Pacific Blue
CD4 PerCP-Cy5.5 CD5 APC
CD5 PerCP-Cy5.5
CD6 CF-Blue CD6 FITC CD6 PE
CD7 CF-Blue
CD8 APC CD8 Biotin
CD8 FITC CD8 OC-515
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
109
Immunology Flow Cytometry Catalog #
Clone
Isotype
Excitation Laser
71-HCD8-PC
143-44
IgG1
Blue
CD9 APC
71-HCD9-A
VJ1/20
IgG2a
Red
CD9 Biotin
71-HCD9-B
VJ1/20
IgG2a
n/a
CD9 CF-Blue
71-HCD9-CB
VJ1/20
IgG2a
Violet
CD9 OC-515
71-HCD9-OC
VJ1/20
IgG2a
Violet
CD9 PerCP
71-HCD9-PC
VJ1/20
IgG2a
Blue
CD10 APC
71-HCD10-A
HI10a
IgG1
Red
70-10AC750 ‡
HI10a
IgG1
Red
71-HCD10-CB
HI10a
IgG1
Violet
71-HCD10-F
HI10a
IgG1
Blue
CD10 PerCP
71-HCD10-PC
HI10a
IgG1
Blue
CD11a APC
71-HCD11A-A
TP1/40
IgG1
Red
CD11a CF-Blue
71-HCD11A-CB
TP1/40
IgG1
Violet
CD11a OC-515
71-HCD11A-OC
TP1/40
IgG1
Violet
71-HCD11B-A
DCIS1/18
IgG2a
Red
71-HCD11B-CB
DCIS1/18
IgG2a
Violet
71-HCD11B-F
DCIS1/18
IgG2a
Blue
CD11b OC-515
71-HCD11B-OC
DCIS1/18
IgG2a
Violet
CD11b PerCP
71-HCD11B-PC
DCIS1/18
IgG2a
Blue
CD11c PerCP
71-HCD11C-PC
BU-15
IgG1
Blue
70-14AP3 ‡
47-3D6
IgG1
Red
71-HCD14-B
47-3D6
IgG1
n/a
CD14 CF-Blue
71-HCD14-CB
47-3D6
IgG1
Violet
CD14 OC-515
71-HCD14-OC
47-3D6
IgG1
Violet
CD14 PerCP
71-HCD14-PC
47-3D6
IgG1
Blue
CD15 CF-Blue
71-HCD15-CB
MCS-1
IgG1
Violet
CD15 PerCP
71-HCD15-PC
MCS-1
IgG1
Blue
71-HCD16-A
3G8
IgG1
Red
Single Color Antibodies CD8 PerCP
CD10 APC-C750 CD10 CF-Blue CD10 FITC
110
CD11b APC CD11b CF-Blue CD11b FITC
CD14 APC CD14 Biotin
CD16 APC
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Single Color Antibodies
Catalog #
Clone
Isotype
Excitation Laser
CD16 Biotin
71-HCD16-B
3G8
IgG1
n/a
71-HCD16-CB
3G8
IgG1
Violet
CD16 FITC
71-HCD16-F
3G8
IgG1
Blue
CD16 FITC
71-HCD16-F.2
GRM1
IgG1
Blue
CD16 PE
71-HCD16-PE
3G8
IgG1
Blue
CD16 PerCP
71-HCD16-PC
3G8
IgG1
Blue
CD18 APC
71-HCD18-A
GRF1
IgG1
Red
CD18 Biotin
71-HCD18-B
GRF1
IgG1
n/a
71-HCD18-CB
GRF1
IgG1
Violet
71-HCD18-F
GRF1
IgG1
Blue
71-HCD18-OC
GRF1
IgG1
Violet
71-HCD19-A
A3-B1
IgG2a
Red
71-HCD19-CB
A3-B1
IgG2a
Violet
CD19 FITC
70-19F4
HD37
IgG1
Blue
CD19 PECy5
70-19C2
J4.119
IgG1
Blue
CD19 PECy7
70-19C5 ‡
J4.119
IgG1
Blue
CD19 PerCP
71-HCD19-PC
A3-B1
IgG2a
Blue
70-19C7
HIB19
IgG1
Blue
CD20 APC
71-HCD20-A
LT20
IgG1
Red
CD20 Biotin
71-HCD20-B
LT20
IgG1
n/a
70-20F3
2H7
IgG2b
Blue
70-20PBZ ‡
2H7
IgG2b
Violet
71-HCD20-PC
LT20
IgG1
Blue
CD21 APC-C750
70-21AC750 ‡
B-ly4
IgG1
Red
CD21 CF-Blue
71-HCD21-CB
HI21a
IgG2a
Violet
CD21 FITC
71-HCD21-F
HI21a
IgG2a
Blue
CD22 APC
71-HCD22-A
HIB22
IgG1
Red
70-22AC750 ‡
MEM-01
IgG1
Red
CD16 CF-Blue
CD18 CF-Blue CD18 FITC CD18 OC-515 CD19 APC CD19 CF-Blue
CD19 PerCP-Cy5.5
CD20 FITC CD20 Pacific Blue CD20 PerCP
CD22 APC-C750
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
111
Immunology Flow Cytometry Catalog #
Clone
Isotype
Excitation Laser
71-HCD22-CB
HIB22
IgG1
Violet
71-HCD22-F
HIB22
IgG1
Blue
71-HCD22-PE
HIB22
IgG1
Blue
CD23 FITC
71-HCD23-F
B-G6
IgG1
Blue
CD24 APC
71-HCD24-A
SN3
IgG1
Red
CD25 APC
71-HCD25-A
TP1/6
IgG2b
Red
CD25 CF-Blue
71-HCD25-CB
TP1/6
IgG2b
Violet
CD25 PerCP
71-HCD25-PC
TP1/6
IgG2b
Blue
CD26 APC
71-HCD26-A
TP1/19
IgG2b
Red
CD26 Biotin
71-HCD26-B
TP1/19
IgG2b
n/a
CD26 CF-Blue
71-HCD26-CB
TP1/19
IgG2b
Violet
CD26 PerCP
71-HCD26-PC
TP1/19
IgG2b
Blue
CD28 FITC
71-HCD28-F
KOLT-2
IgG1
Blue
CD29 APC
71-HCD29-A
VJ1/14
IgG2b
Red
CD29 Biotin
71-HCD29-B
VJ1/14
IgG2b
n/a
CD29 CF-Blue
71-HCD29-CB
VJ1/14
IgG2b
Violet
CD29 OC-515
71-HCD29-OC
VJ1/14
IgG2b
Violet
CD29 PerCP
71-HCD29-PC
VJ1/14
IgG2b
Blue
CD31 Biotin
71-HCD31-B
TP1/15
IgG2a
n/a
CD31 CF-Blue
71-HCD31-CB
TP1/15
IgG2a
Violet
CD31 OC-515
71-HCD31-OC
TP1/15
IgG2a
Violet
CD33 APC
71-HCD33-A
HIM3-4
IgG1
Red
CD33 Biotin
71-HCD33-B
HIM3-4
IgG1
n/a
71-HCD33-CB
HIM3-4
IgG1
Violet
71-HCD36-F
TR9
IgG1
Blue
CD36 PE
71-HCD36-PE
TR9
IgG1
Blue
CD38 APC-C750
70-38AC750 ‡
LD38
IgG1
Red
71-HCD38-CB
GR7A4
IgG1
Violet
Single Color Antibodies CD22 CF-Blue CD22 FITC CD22 PE
112
CD33 CF-Blue CD36 FITC
CD38 CF-Blue
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Catalog #
Clone
Isotype
Excitation Laser
71-HCD38-DY
GR7A4
IgG1
Red
70-38F
LD38
IgG1
Blue
71-HCD38-OC
GR7A4
IgG1
Violet
CD40 APC
71-HCD40-A
HI40a
IgG1
Red
CD40 Biotin
71-HCD40-B
HI40a
IgG1
n/a
CD40 CF-Blue
71-HCD40-CB
HI40a
IgG1
Violet
CD40 PerCP
71-HCD40-PC
HI40a
IgG1
Blue
CD41 APC
71-HCD41-A
HIP8
IgG1
Red
CD41 Biotin
71-HCD41-B
HIP8
IgG1
n/a
71-HCD41-CB
HIP8
IgG1
Violet
71-HCD41-F
HIP8
IgG1
Blue
CD41 PerCP
71-HCD41-PC
HIP8
IgG1
Blue
CD42a APC
71-HCD42A-A
GR-P
IgG2a
Red
CD42a Biotin
71-HCD42A-B
GR-P
IgG2a
n/a
71-HCD42A-CB
GR-P
IgG2a
Violet
71-HCD42A-F
GR-P
IgG2a
Blue
71-HCD42A-OC
GR-P
IgG2a
Violet
CD42a PE
71-HCD42A-PE
GR-P
IgG2a
Blue
CD42a PerCP
71-HCD42A-PC
GR-P
IgG2a
Blue
CD42a PURE
71-HCD42A-PU
GR-P
IgG2a
n/a
CD42b APC
71-HCD42B-A
HIP1
IgG1
Red
CD42b Biotin
71-HCD42B-B
HIP1
IgG1
n/a
71-HCD42B-CB
HIP1
IgG1
Violet
71-HCD42B-F
HIP1
IgG1
Blue
71-HCD42B-PC
HIP1
IgG1
Blue
71-H43-B
TP1/36
IgG1
n/a
CD43 CF-Blue
71-H43-CB
TP1/36
IgG1
Violet
CD43 OC-515
71-HCD43-OC
TP1/36
IgG1
Violet
Single Color Antibodies CD38 DY-634 CD38 FITC CD38 OC-515
CD41 CF-Blue CD41 FITC
CD42a CF-Blue CD42a FITC CD42a OC-515
CD42b CF-Blue CD42b FITC CD42b PerCP CD43 Biotin
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
113
Immunology Flow Cytometry Catalog #
Clone
Isotype
Excitation Laser
71-HCD43-PC
TP1/36
IgG1
Blue
71-HCD44-A
HI44a
IgG1
Red
CD44 CF-Blue
71-HCD44-CB
HI44a
IgG1
Violet
CD44 PerCP
71-HCD44-PC
HI44a
IgG1
Blue
70-45AC750 ‡
GA90
IgG2a
Red
CD45 CF-Blue
71-HCD45-CB
D3/9
IgG1
Violet
CD45 CF-Blue
71-HCD45-CB.2
HI30
IgG1
Violet
CD45 DY-634
71-HCD45-DY
D3/9
IgG1
Red
CD45 OC-515
71-HCD45-OC
D3/9
IgG1
Violet
CD45 OC-515
70-45OC ‡
GA90
IgG2a
Violet
CD45 PECy5
71-HCD45-PEC5
IMMU19.2
IgG1
Blue
CD45 PECy5
70-45C3
MMU19.2
IgG1
Blue
CD45 PerCP
71-HCD45-PC
D3/9
IgG1
Blue
CD45 PerCP
71-HCD45-PC.2
HI30
IgG1
Blue
CD45RA APC
71-HCD45RA-A
HI100
IgG1
Red
CD45RA CF-Blue
71-HCD45RA-CB
GRT22
IgG1
Violet
CD45RA CF-Blue
71-HCD45RA-CB.2
HI100
IgG1
Violet
71-HCD45RA-PC
HI100
IgG1
Blue
71-HCD45RB-A
MC5/2
IgG1
Red
71-HCD45RB-CB
MC5/2
IgG1
Violet
CD45RB FITC
71-HCD45RB-F
MC5/2
IgG1
Blue
CD45RC APC
71-HCD45RC-A
RP1/12
IgG1
Red
CD45RC FITC
71-HCD45RC-F
RP1/12
IgG1
Blue
71-HCD45RC-PU
RP1/12
IgG1
n/a
71-HCD49B-A
TEA1/41
IgG1
Red
71-HCD49B-CB
TEA1/41
IgG1
Violet
71-HCD49B-F
TEA1/41
IgG1
Blue
71-HCD49B-PE
TEA1/41
IgG1
Blue
Single Color Antibodies CD43 PerCP CD44 APC
CD45 APC-C750
114
CD45RA PerCP CD45RB APC CD45RB CF-Blue
CD45RC PURE CD49b APC CD49b CF-Blue CD49b FITC CD49b PE
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Catalog #
Clone
Isotype
Excitation Laser
71-HCD49C-A
VJ1/6
IgG1
Red
71-HCD49C-CB
VJ1/6
IgG1
Violet
71-HCD49C-F
VJ1/6
IgG1
Blue
71-HCD49C-PE
VJ1/6
IgG1
Blue
CD49d APC
71-HCD49D-A
ALC1/1
IgG1
Red
CD49d Biotin
71-HCD49D-B
ALC1/1
IgG1
n/a
71-HCD49D-CB
ALC1/1
IgG1
Violet
71-HCD49D-F
ALC1/1
IgG1
Blue
71-HCD49D-PC
ALC1/1
IgG1
Blue
CD52 APC
71-HCD52-A
HI186
IgG2b
Red
CD52 Biotin
71-HCD52-B
HI186
IgG2b
n/a
71-HCD52-CB
HI186
IgG2b
Violet
71-HCD52-F
HI186
IgG2b
Blue
CD52 PE
71-HCD52-PE
HI186
IgG2b
Blue
CD52 PerCP
71-HCD52-PC
HI186
IgG2b
Blue
CD53 APC
71-HCD53-A
HI29
IgG1
Red
CD53 Biotin
71-HCD53-B
HI29
IgG1
n/a
71-HCD53-CB
HI29
IgG1
Violet
71-HCD53-F
HI29
IgG1
Blue
CD53 PE
71-HCD53-PE
HI29
IgG1
Blue
CD53 PerCP
71-HCD53-PC
HI29
IgG1
Blue
71-HCD56-A
B-A19
IgG1
Red
70-56AC750 ‡
C5.9
IgG2b
Red
71-HCD56-B
B-A19
IgG1
n/a
70-56PE ‡
C5.9
IgG2b
Blue
71-HCD56-PU
B-A19
IgG1
n/a
71-HCD57-F
HI57a
IgM
Blue
71-HCD57-PU
HI57a
IgM
n/a
Single Color Antibodies CD49c APC CD49c CF-Blue CD49c FITC CD49c PE
CD49d CF-Blue CD49d FITC CD49d PerCP
CD52 CF-Blue CD52 FITC
CD53 CF-Blue CD53 FITC
CD56 APC CD56 APC-C750 CD56 Biotin CD56 PE CD56 PURE CD57 FITC CD57 PURE
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
115
Immunology Flow Cytometry Single Color Antibodies
Catalog #
Clone
Isotype
Excitation Laser
CD58 APC
71-HCD58-A
HI58a
IgG1
Red
71-HCD58-CB
HI58a
IgG1
Violet
71-HCD58-F
HI58a
IgG1
Blue
71-HCD58-PE
HI58a
IgG1
Blue
CD59 APC
71-HCD59-A
VJ1/12,2
IgG2a
Red
CD59 Biotin
71-HCD59-B
VJ1/12,2
IgG2a
n/a
71-HCD59-CB
VJ1/12,2
IgG2a
Violet
71-HCD59-F
VJ1/12,2
IgG2a
Blue
71-HCD59-OC
VJ1/12,2
IgG2a
Violet
CD59 PE
71-HCD59-PE
VJ1/12,2
IgG2a
Blue
CD59 PerCP
71-HCD59-PC
VJ1/12,2
IgG2a
Blue
CD61 PerCP
71-HCD61-PC
C17
IgG1
Blue
CD62E APC
71-HCD62E-A
TEA2/1
IgG2b
Red
CD62E FITC
71-HCD62E-F
TEA2/1
IgG2b
Blue
CD62L APC
71-HCD62L-A
HI62L
IgG2a
Red
CD62L CF-Blue
71-HCD62L-CB
HI62L
IgG2a
Violet
CD62L PerCP
71-HCD62L-PC
HI62L
IgG2a
Blue
71-HCD62P-A
P.seK02.22
IgG2b
Red
CD62P CF-Blue
71-HCD62P-CB
P.seK02.22
IgG2b
Violet
CD62P PerCP
71-HCD62P-PC
P.seK02.22
IgG2b
Blue
CD63 APC
71-HCD63-A
TEA3/18
IgG1
Red
CD63 Biotin
71-HCD63-B
TEA3/18
IgG1
n/a
71-HCD63-CB
TEA3/18
IgG1
Violet
71-HCD63-F
TEA3/18
IgG1
Blue
71-HCD63-OC
TEA3/18
IgG1
Violet
CD63 PE
71-HCD63-PE
TEA3/18
IgG1
Blue
CD63 PerCP
71-HCD63-PC
TEA3/18
IgG1
Blue
CD64 PE
71-HCD64-PE
10.1
IgG1
Blue
71-HCD69-A
FN50
IgG1
Red
CD58 CF-Blue CD58 FITC CD58 PE
CD59 CF-Blue CD59 FITC CD59 OC-515
116
CD62P APC
CD63 CF-Blue CD63 FITC CD63 OC-515
CD69 APC
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Catalog #
Clone
Isotype
Excitation Laser
71-HCD71-CB
FG2/12
IgG1
Violet
71-HCD71-F
FG2/12
IgG1
Blue
CD71 PerCP
71-HCD71-PC
FG2/12
IgG1
Blue
CD81 APC-C750
70-81AC750 ‡
M38
IgG1
Red
CD86 FITC
71-HCD86-F
BU63
IgG1
Blue
CD98 APC
71-HCD98-A
FG1/8
IgG1
Red
CD98 Biotin
71-HCD98-B
FG1/8
IgG1
n/a
CD98 CF-Blue
71-HCD98-CB
FG1/8
IgG1
Violet
CD98 PE
71-HCD98-PE
FG1/8
IgG1
Blue
CD98 PerCP
71-HCD98-PC
FG1/8
IgG1
Blue
CD99 APC
71-HCD99-A
HI156
IgG2a
Red
CD99 Biotin
71-HCD99-B
HI156
IgG2a
n/a
71-HCD99-CB
HI156
IgG2a
Violet
71-HCD99-F
HI156
IgG2a
Blue
CD99 PerCP
71-HCD99-PC
HI156
IgG2a
Blue
CD105 APC
71-H105A-PC
2H6F11
IgG1
Red
CD105 CF-Blue
71-HCD105-CB
2H6F11
IgG1
Violet
CD105 OC-515
71-HCD105-OC
2H6F11
IgG1
Violet
CD105 PerCP
71-HCD105-PC
2H6F11
IgG1
Blue
CD117 APC
71-HCD117-A
104D2
IgG1
Red
CD138 APC-C750
70-138AC750
B-A38
IgG1
Red
70-138F4
B-A39
IgG2
Blue
70-138PE4
B-A38
IgG1
Blue
71-HCD147-A
VJ1/9
IgG1
Red
71-HCD147-CB
VJ1/9
IgG1
Violet
71-HCD147-F
VJ1/9
IgG1
Blue
CD147 PE
71-HCD147-PE
VJ1/9
IgG1
Blue
CD147 PerCP
71-HCD147-PC
VJ1/9
IgG1
Blue
CD235a APC
71-HC235A-A
HI264
IgG2a
Red
Single Color Antibodies CD71 CF-Blue CD71 FITC
CD99 CF-Blue CD99 FITC
CD138 FITC CD138 PE CD147 APC CD147 CF-Blue CD147 FITC
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
117
Immunology Flow Cytometry Catalog #
Clone
Isotype
Excitation Laser
71-HC235A-CB
HI264
IgG2a
Violet
71-HC235A-F
HI264
IgG2a
Blue
CD235a PE
71-HC235A-PE
HI264
IgG2a
Blue
Anti Caspase-3 active PURE
71-HCASP3-PU
IgG
n/a
Anti-cKit PURE
71-HCKIT-PU
IgG
n/a
Anti-GST PURE
71-HGST-PU
IM14/21
IgG
n/a
Anti-IL8 PURE
71-HIL8-PU
IL8-1505
IgG2a
n/a
71-HLMO1-PU
LMO1-1201
IgG2a
n/a
71-HCPA-A
CA2
IgG
Red
70-3PBZ ‡
UCHT-1
CyCD79a PE
70-79APE ‡
HM57
IgG1
Blue
CyMPO FITC
70-MPOF3 ‡
2C7
IgG1
Blue
cyTCRβ APC
70-bF1AP
8A3
IgG1
Red
71-HHLADP-A
HI43
IgG1
Red
71-HHLADP-CB
HI43
IgG1
Violet
71-HHLADP-F
HI43
IgG1
Blue
HLA-DP PE
71-HHLADP-PE
HI43
IgG1
Blue
HLA-DP PURE
71-HHLADP-PU
HI43
IgG1
n/a
HLA-DQ APC
71-HHLADQ-A
HI118
IgG1
Red
71-HHLADQ-CB
HI118
IgG1
Violet
HLA-DQ FITC
71-HHLADQ-F
HI118
IgG1
Blue
HLA-DR APC
71-HHLADR-A
GRB-1
IgG2a
Red
HLA-DR Biotin
71-HHLADR-B
GRB-1
IgG2a
n/a
71-HHLADR-CB
GRB-1
IgG2a
Violet
71-HHLADR-F
GRB-1
IgG2a
Blue
71-HHLADR-OC
GRB-1
IgG2a
Violet
HLA-DR PE
71-HHLADR-PE
GRB-1
IgG2a
Blue
HLA-DR PerCP
71-HHLADR-PC
GRB-1
IgG2a
Blue
Single Color Antibodies CD235a CF-Blue CD235a FITC
Anti-LMO1 PURE CPA APC CycCD3 Pacific Blue
118
HLA-DP APC HLA-DP CF-Blue HLA-DP FITC
HLA-DQ CF-Blue
HLA-DR CF-Blue HLA-DR FITC HLA-DR OC-515
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Violet
Catalog #
Clone
Isotype
Excitation Laser
71-HIREM2-F
UP-H2
IgG2a
Blue
71-HIREM2-PC
UP-H2
IgG2a
Blue
Kappa APC
70-KappaP
Polyclonal
Red
Kappa FITC
70-KAPPF2
Polyclonal
Blue
Kappa PE
70-KAPPPE ‡
Polyclonal
Blue
Lambda APC-C750
70-LAC750 ‡
Polyclonal
Red
Lambda FITC
70-LAMBF ‡
Polyclonal
Blue
Lambda APC
70-LAMBAP
Polyclonal
Red
Lambda APC
71-HLAMBD-A
HIgλ
70-LAMBPE
Polyclonal
71-HLAMBDA-CB
Higλ
IgG7
Violet
Catalog #
Clone
Isotype
Excitation Laser
CD3 FITC/CD4 PE
70-3F8-4PE9
Cris-7, Edu-2
IgG2a, IgG2a
Blue
CD3 FITC/CD8 PE
70-3F8-8PE4
Cris-7, 17D8
IgG2a, IgG1
Blue
CD3 FITC/CD16 PE
70-3F8-16PE7
Cris-7, 3G8
IgG2a , IgG1
Blue
CD3 FITC/CD19 PE
70-3F8-19PE5
Cris-7, HD37
IgG2a, IgG1
Blue
CD3 FITC/CD56 PE
70-3F8-56PE
Cris-7, C5.9
IgG2a, IgG2b
Blue
CD3 FITC/HLADR PE
70-3F8-DRPE
Cris-7, 423L
IgG2a, IgG2a
Blue
CD4 FITC/CD8 PE
70-4F6-8PE4
Edu-2, 17D8
IgG2a, IgG1
Blue
CD4 FITC/CD45 PE
70-4F6-45PE4
Edu-2, D3/9
IgG2a, IgG1
Blue
CD5 FITC/CD19 PE
70-5F4-19PE5
MCD5, HD37
IgG2b, IgG1
Blue
CD8 FITC/CD16 PE
70-8F8-16PE7
UCH-T4, 3G8
IgG2a, IgG1
Blue
CD8 FITC/CD56 PE
70-8F8-56PE
UCH-T4, C5.9
IgG2a, IgG2b
Blue
CD45 FITC/CD14PE
70-45F5-14PE3
EO1, 47-3D6
gG2a, IgG1
Blue
HLA B27 FITC/HLA B7 PE
70-COMB1012
HLA ABC m3, BB7.1
IgG2a, IgG1
Blue
Single Color Antibodies IREM-2 FITC IREM-2 PerCP
Lambda-PE Lambda CF-Blue
Multicolor Combinations
IgG6
Red Blue
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
119
Immunology Flow Cytometry
120
Catalog #
Clone
IgG1 FITC/IgG1 PE
70-IC5F5PE
MCG1, MCG1
Blue
IgG1 FITC/IgG2a PE
70-IC5F6PE
MCG1, MCG2a
Blue
IgG1 FITC/IgG2b PE
70-IC5F7PE
MCG1, MCG2b
Blue
IgG2a FITC/IgG1 PE
70-IC6F5PE
MCG2a, MCG1
Blue
IgG2a FITC/IgG2a PE
70-IC6F6PE
MCG2a, MCG2a
Blue
IgG2a FITC/IgG2b PE
70-IC6F7PE
MCG2a, MCG2b
Blue
IgG2b FITC/IgG1 PE
70-IC7F5PE
MCG2b, MCG1
Blue
IgG2b FITC/IgG2a PE
70-IC7F6PE
MCG2b, MCG2a
Blue
IgG2b FITC/IgG2b PE
70-IC7F7PE
MCG2b, MCG2b
Blue
Kappa FITC/CD19 PE
70-KF2-19PE5
Blue
70-KF2-LPE
Blue
70-LF-19PE5
Blue
70-LF-KPE
Blue
Kappa FITC/LAMBDA PE Lambda FITC/CD19 PE LAMBDA FITC/Kappa PE
Isotype
Excitation Laser
Multicolor Combinations
CD3 FITC/CD4 PE/CD8 PECy5
70-3F8-4PE9-8C2
Cris-7, Edu-2, B9.11
IgG2a, IgG2a, IgG1
Blue
CD3 FITC/CD4 PE/CD19 PECy5
70-3F8-4PE9-19C2
Cris-7, Edu-2, J4.119
IgG2a, IgG2a, IgG1
Blue
CD3 FITC/CD4 PE/CD45 PECy5
70-3F8-4PE9-45C3
Cris-7, Edu-2, IMMU19.2
IgG2a, IgG2a, IgG1
Blue
CD3 FITC/CD8 PE/CD19 PECy5
70-3F8-8PE4-19C2
Cris-7, 17D8, J4.119
IgG2a, IgG1, IgG1
Blue
CD3 FITC/CD8 PE/CD45 PECy5
70-3F8-8PE4-45C3
Cris-7, 17D8, IMMU19.2
IgG2a, IgG1, IgG1
Blue
CD3 FITC/CD16 PE/CD19 PECy5
70-3F8-16PE7-19C2
Cris-7, 3G8, J4.119
IgG2a, IgG1, IgG1
Blue
CD3 FITC/CD16+56 PE/CD19 PECy5
70-3F8-16PE7+56PE19C2
Cris-7, 3G8+C5.9, J4.119
IgG2a, IgG1+IgG2b, IgG1
Blue
CD3 FITC/CD16+56 PE/CD45 PECy5
70-3F8-16PE7+56PE45C3
Cris-7, 3G8+C5.9, IMMU19.2
IgG2a, IgG1+IgG2b, IgG1
Blue
CD3 FITC/CD19 PE/CD45 PECy5
70-3F8-19PE5-45C3
Cris-7, HD37, IMMU19.2
IgG2a, IgG1, IgG1
Blue
CD3 FITC/CD56 PE/CD19 PECy5
70-3F8-56PE-19C2
Cris-7, C5.9, J4.119
IgG2a, IgG2b, IgG1
Blue
70-4F6-8PE4-3C4
Edu-2, 17D8, UCHT1
IgG2a, IgG1, IgG1
Blue
70-4F6-8PE4-45C3
Edu-2, 17D8, IMMU19.2
IgG2a, IgG1, IgG1
Blue
CD8 FITC/CD4 PE/CD3 PECy5
70-8F8-4PE9-3C4
UCH-T4, Edu-2, UCHT1
IgG2a, IgG2a, IgG1
Blue
CD8 FITC/CD4 PE/CD19 PECy5
70-8F8-4PE9-19C2
UCH-T4, Edu-2, J4.119
IgG2a, IgG2a, IgG1
Blue
CD4 FITC/CD8 PE/CD3 PECy5 CD4 FITC/CD8 PE/CD45 PECy5
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
Catalog #
Clone
Isotype
Excitation Laser
CD8 FITC/CD4 PE/CD45 PECy5
70-8F8-4PE9-45C3
UCH-T4, Edu-2, IMMU19.2
IgG2a, IgG2a, IgG1
Blue
CD10 FITC/CD5 PE/CD19 PECy5
70-10F1-5PE4-19C2
SN5c, MCD5, J4.119
IgG1, IgG2b, IgG1
Blue
CD16 FITC/CD19 PE/CD3 PECy5
70-16F6-19PE5-3C4
3G8, HD37, UCHT1
IgG1, IgG1, IgG1
Blue
CD56 FITC/CD19 PE/CD3 PECy5
70-56F-19PE5-3C4
C5.9, HD37, UCHT1
IgG2b, IgG1, IgG1
Blue
70-FMC7F-23PE3-19C2
FMC7, B-G6, J4.119
IgM, IgG1, IgG1
Blue
IgG1 FITC/IgG1 PE/IgG1 PECy5
70-IC5F5PE5C
MCG1, MCG1, ZX3
Blue
IgG1 FITC/IgG2a PE/IgG1 PECy5
70-IC5F6PE5C
MCG1, MCG2a, ZX3
Blue
IgG1 FITC/IgG2b PE/IgG1 PECy5
70-IC5F7PE5C
MCG1, MCG2b, ZX3
Blue
IgG2a FITC/IgG1 PE/IgG1 PECy5
70-IC6F5PE5C
MCG2a, MCG1, ZX3
Blue
IgG2a FITC/IgG2a PE/IgG1 PECy5
70-IC6F6PE5C
MCG2a, MCG2a, ZX3
Blue
IgG2a FITC/IgG2b PE/IgG1 PECy5
70-IC6F7PE5C
MCG2a, MCG2b, ZX3
Blue
IgG2b FITC/IgG1 PE/IgG1 PECy5
70-IC7F5PE5C
MCG2b, MCG1, ZX3
Blue
IgG2b FITC/IgG2a PE/IgG1 PECy5
70-IC7F6PE5C
MCG2b, MCG2a, ZX3
Blue
IgG2b FITC/IgG2b PE/IgG1 PECy5
70-IC7F7PE5C
MCG2b, MCG2b, ZX3
Blue
Kappa FITC/Lambda PE/CD19 PECy5
70-KF2-LPE-19C2
Polyclonal, Polyclonal, J4.119
Polyclonal, Polyclonal, IgG1
Blue
Kappa FITC/Lambda PE/CD19 PECy5
70-KF2-LPE-19C2-50
Polyclonal, Polyclonal, J4.119
Polyclonal, Polyclonal, IgG1
Blue
Lambda FITC/Kappa PE/CD19 PECy5
70-LF-KPE-19C2
Polyclonal, Polyclonal, J4.119
Polyclonal, Polyclonal, IgG1
Blue
70-45F5-8PE4-4C3-3AP6
EO1, 17D8, 13B8.2, GA60
IgG2a, IgG1, IgG1, IgG1
Blue, Red
Multicolor Combinations
FMC7 FITC/CD23 PE/CD19PECy5
CD45 FITC/CD8 PE/CD4 PECy5/ CD3 APC
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
121
Immunology Flow Cytometry EuroFlow™ Validated Screening Tubes Product
Catalog #
Description
Acute Leukemia Orientation Tube (ALOT-7)
70-ALOT7
7 conjugated antibodies designed for initial assessment of the nature of immature populations of hematopoietic cells in acute leukemia samples in order to allow appropriate orientation towards the complementary B, T lineage, and AML/MDS antibody panels.
70-SST10
11 conjugated antibodies designed for the detection of normal and aberrant lymphocyte populations of B, T and NK lineage by flow cytometry. This 8-color panel can be used for evaluation of “small” samples and samples with (very) low cell counts, such as fine needle aspirates (FNA), cerebrospinal fluid (CSF), vitreous humor, etc. with a suspicion of primary lymphoma.
70-LST11
11 conjugated antibodies designed for the detection of aberrant mature lymphocyte populations of B, T and NK lineage by flow cytometry. This 8-color panel can be used for evaluation of several suspected conditions, such as lymphocytosis, lymph node enlargement, splenomegaly, monoclonal serum components, unexplained cytopenias, etc.
Small Sample Screening Tube (SST)
Lymphoid Screening Tube (LST-11)
122
EuroFlow™ Validated Panels
Infinicyt™ Data Analysis Software
Product
Catalog #
Description
Product
Catalog #
Studies of Major Lymphocyte Subpopulations (Two Color)
70-SPLC-25
CD8 + SmIgλ-FITC CD56 + SmIgK-PE
Basic Module Infinicyt™
70-INFINICYT-P 70-INFINICYT-ADV1
70-SPLC4-25
CD8 + SmIgλ-FITC CD56 + SmIgK-PE CD4-PerCP-Cy5.5
Advanced Module Infinicyt™
Studies of Major Lymphocyte Subpopulations (Three Color)
Products are for Research Use Only unless otherwise noted
‡
Indicates an Analyte Specific Reagent
123
Accessories & Equipment Gastroenterology
124
Accessories & Equipment Type
Description
Catalog #
Quantum Blue® Lateral Flow Reader
02-BI-POCTR-ABS ^
Columns
11,12-DHET Immunoaffinity Columns
60-DH32
Columns
Angiotensin II/Vasopressin Extraction Columns
02-A22/B-AEC
Columns
Chromobond Columns
30-C-SE2112
Columns
GLP-1 Sample Extraction Columns
43-GLPHU-SE50
Columns
Melatonin Extraction Columns
02-MEL/B-MEC
Saliva Collection
Salivettes (Sterile Saliva Collection Devices)
02-MEL/B-SVC
Saliva Collection
SleepCheck Saliva Melatonin Collection Kit
01-B-SLEEPCHECK16
Stool Collection
EasySampler® Stool Collection Kit
58-EZSAMPLER
Stool Collection
Histamine ELISA Stool Collection Device
17-BA-D-1241
Stool Collection & Extraction
ScheBo® Quick-Prep Fecal Sample Extraction Kit
02-B-CAL-SO50
Stool Collection & Extraction
Smart-Prep Fecal Sample Extraction Kit
02-B-CAL-RD
Other
Basiskit for LIA
14-HD-371.0
Other
Care™ Fecal Occult Blood Rapid Testing Rack
43-FOBHU-RACK
Other
Microplate Rotator (4 plate)
06-S2020-P4
Other
Microplate Seal Film
06-SEAL-FILM
Other
Non-Sterile Dispenser Syringe Tips
06-ST-3
Equipment
Products are for Research Use Only unless otherwise noted
*
FDA Registered for In Vitro Diagnostic Use
125
^
Health Canada Licensed
Index Index
126
5a-Androstane-3a, 17b-diol Glucuronide 48, 93
Albumin 39, 100, 101
Anti-Inositol-GM 68
5-HIAA 93
Aldosterone 28 , 34, 48
Anti-Insulin Autoantibodies (AIA) 39, 40, 66, 68, 81
6-Sulfatoxymelatonin 93
Alpha-1 Thymosin 59
Anti-Intrinsic Factor 68
8-isoPGF2a 29
Alpha-Fetoprotein (AFP) 48 , 101
Anti-Jo-1 69
20-HETE 28
Alpha-Lactalbumin 66
Anti-LC1 69
α-1-Acid Glycoprotein (AGP) 66, 100
Amanitin 101
Anti-LKM-1 69
α-1-Antichymotrypsin 48 , 58
ANA 66, 75
Anti-M2 69
α-1-Microglobulin 100
Androstenedione 48
Anti-MAG 69, 93
α-2-Macroglobulin 100
Angiotensin 28 , 30, 34, 48 , 125
Anti-Ovalbumin 8 , 60, 69
α-Fodrin 58 , 66
Angiotensin Converting Enzyme (ACE) 28, 29, 48, 66
Anti-Ovarian Antibody 69
α-MSH 48 , 93
Annexin V 66
Antioxidative Capacity 30
ß-2 Microglobulin 101
ANP 29, 30, 100, 101
Anti-Phosphatidyl-Serine 69
ß-4 Thymosin 87
Anti-ANCA 66
Anti-Phospholipid-8 69
ß-Catenin 66, 76
Anti-BPI 66
Anti-Prothrombin 69
ß hCG 48
Anti-Cag-A 6
Anti-Rheumatoid Factor (RF) 69
Anti-Candida 6
Anti-Ps-Aeruginosa 8
A
Anti-Cardiolipin 67
Anti-Ribosomal P 69
A Proliferation Inducing Ligand (APRIL) 71
Anti-Casein 6, 59, 67
Anti-Rubella 8 , 69
Acid Labile Subunit 48
Anti-CaSR 67
Anti-Saccharomyces Cerevisiae (Crohns Check) 61, 75
AcSDKP 29
Anti-CCP (CCPlus Immunoscan®) 72, 73
Anti-Scl 70 70
Adenosine 29
Anti-CENP-B 67
Anti-SGPG 70, 92, 93
Adenovirus 6
Anti-Cytomegalovirus 6, 7, 67
Anti-SLA 70
Adipocyte Fatty Acid Binding Protein 38
Anti-ds-DNA 67
Anti-Sm 70
ADH 35, 54
Anti-Elastase 67
Anti-Soya 8 , 60, 70
ADH/AVP 35, 54
Anti-Gliadin 7, 59, 67
Anti-Sperm Antibody 48 , 70
Adiponectin 38 , 42
Anti-GM1 Autoantibodies 93
Anti-SS 70
ADMA 29, 30
Anti-Helicobacter Pylori 7, 8 , 59, 60, 68
Anti-ß 2 Glycoprotein 70
Adrenocorticotropic Hormone (ACTH) 29, 48 , 93
Anti-Histone 68
Anti-ss-DNA ELISA 70
AKT1/2 66
Anti-IFN ß 68 , 93
Anti-ß Lactoglobulin 70
Antithrombin 30, 70
Carbonylated Protein 31
Connective Tissue Factor (CTGF) 23 , 75
Anti-Thyroid Peroxidase Antibody (TPO) 49, 54
Cardiolipin 67, 73
Corticosterone 49
Anti-U1-70 71
Cartilage Oligomeric Matrix Proetin (Hcomp) 23
Corticotropin Releasing Factor (CRF) 31, 94
AOPP 30
Casomorphin 8 , 60
Cortisol 49
Apolipoprotein 30
Caspase 73, 118
C-Peptide 39
ASCA 66, 71
Cathepsin 22, 67, 73
C-Reactive Protein (CRP) 74, 75
Aspergillus 8 , 17, 71
CD153 73
Creatine Kinase ELISA 31, 102
AVP 35, 54
CEA 73
CREB ELISA 75
Cell Adhesion Molecule (L1-CAM) 82
Cripto-1 75
B
Cell Proliferation & Toxicity 74
CRP 31, 74, 75
BAFF 71
Cellular Adhesion Molecule (sICAM-2) 87
C. Trachomatis 8 , 71
Basophil Activation (FlowCAST速) 10, 61
Cellular Adhesion Molecule (sICAM-3) 87
Cu/ZnSOD 75
Bcl-2 71
Cellular Adhesion Molecule (sVCAM-1) 88
Cystatin C 100, 102
Biotin 60, 109, 110, 111, 112, 113, 115, 116, 117, 118
Ceruloplasmin 31
Cytochrome C 75
Blastocystis Antigen 71
CETP 31
Cytokeratin Fragment (CYFRA) 75
BNP 29, 30, 100, 102
cGMP 94
Bone Sialoprotein 22
Chemerin 74
D
Bordetella Pertussis 8 , 71
Chlamydia 6, 9, 74
DAO 9, 31, 61
Bradykinin 30, 94
Cholecystokinin (CCK) 39, 49
Dengue 9, 75
Brucella 8
Chromogranin A 49, 94
Deoxypyridinoline (DPD) 23
Chrorionic Gonadotropin (hCG) 48 , 50
DHEA 49
C
Chymotrypsin 61, 74
DHET 28 , 125
C4a 71
Ciculating Immune Complex (C1q) 67, 74
DHT 49
C5a 71
CINC-1 74
DKK-1 23
Calcitonin 22, 49
Citrullinated Protein Antibodies (CPA) 75, 118
Dopamine 94, 96, 97
Calcitonin Gene Related Peptide (CGRP) 94
Clusterin 100, 102
Calprotectin 57, 58 , 60, 71, 72
c-Met 49
cAMP 94
Complement Factor 3 74
Cancer Antigen 72, 73
Complement System 74, 75
127
Index
128
E
GanglioCombi® Anti-Ganglioside 76, 94
Hemopexin 33
Echinococcus Granulosus 9
Gastrin RIA 39, 61
Hepcidin 33, 50, 51
Endostatin 31, 102
G-CSF 76
HER-2 77
Endothelin 31
GFAP 94
Herpes 8 , 10, 68 , 77
Eosinophil Derived Neurotoxin (EDN) 61
GHB 96, 102
Histamine 10, 77, 125
Eotaxin 76
Ghrelin 38 , 39
Homocysteine 33, 51
Epidermal Growth Factor (EGF) 76
Gliadorphin 61
Human Anti-Human Antibody (HAHA) 76
Epinephrine 93 , 94, 96, 97
Glicentin 39
Human Placental Lactogen (HPL) 51
Epstein Barr Virus 9
Glomerular Basement Membrance (GBM) 30, 67
Hydroxy Pyridinium Crosslinks (PYD/DPD) 23
ERK1/2 76
GLP-1 39, 41, 125
Erythropoietin (EPO) 31, 49
GLP-2 40
I
Estradiol 48 , 49
Glucagon 40, 41
IFN-gamma 77
Estriol 49
Glutamate 16, 96
IgA 6, 7, 8 , 9, 10, 11, 12, 58 , 59, 60, 61, 62, 66, 67, 68 , 69,
Estrone 49
Glutathione 32, 40, 50
70, 71, 73, 74, 75, 77, 78 , 86
GM-CSF 76
IgD 78
F
GPx Activity 32
IgE 5, 6, 7, 78
Fasciola Hepatica 9
Granzyme 76
IGF-1 50, 51
Ferritin 31, 49
Growth Hormone 50, 51
IGF-2 52
Fetuin-A 23 , 31
GSK3α/ß 66, 76
IGFBP-1 52
FGF 39, 50, 76
GST 32, 99, 100, 101, 102, 103 , 118
IGFBP-2 51, 52
FGF-21 39, 76
IGFBP-3 51, 52
Fibrinogen 31, 32
H
IgG 6, 7, 8 , 9, 10, 11, 12, 39, 58 , 59, 60, 61, 66, 67, 68 ,
Fibronectin 32
Haptoglobin 32, 61, 76, 77, 102
69, 70, 71, 72, 73, 74, 75, 78 , 81, 82, 83 , 84, 86, 89, 91,
Folicle Stimulating Hormone (FSH) 50
HAV 7, 67, 68
95, 118
HBc 68
IgG1 78 , 108 , 109, 110, 111, 112, 113, 114, 115, 116, 117,
G
HBs 68
118 , 119, 120, 121
GABA 94
HBsAg 77
IgG2A 78
GAD 39, 76
HCV 7, 68
IgG2B 78
Galectin-3 32, 76
Hemoglobin 32, 61
IgG3 78
IgM 6, 7, 8 , 9, 10, 11, 12, 60, 67, 68 , 69, 70, 73, 74, 75, 77,
Insulin 39, 40, 41, 42, 44, 50, 51, 68 , 81
MCP-1 42, 82
78 , 82, 83 , 89, 91, 92, 93 , 95, 115, 121
IP-10 81
Measles 10, 82
IgY 78
Islet Cell Antibody 42, 81
Melatonin 96, 97, 125 Metanephrine 94, 96
IL-1RA 80 IL-1ß 40, 80
J
Microalbumin 42, 102
IL-1α 80
Japanese Encephalitis 10, 81, 82
MPO ELISA 33, 69, 82 MRP 8/14 ELISA 33, 62, 82
IL-2 80 IL-3 80
K
Mumps 11
IL-4 81
Kappa 82, 119, 120, 121
Mycobacterium Tuberculosis 11, 82
IL-5 81
KIM-1 100, 102
Mycoplasma Hominis 11
IL-6 23 , 24, 40, 81
Krytopyrrole 33
Myoglobin 33, 103
IL-8 40, 81
Myostatin 24, 43 , 52
IL-9 81
L
IL-10 78 , 79
Lactoferrin 61, 82
N
IL-12 79
Lambda 82, 119, 120, 121
NAG 103
IL-13 ELISA 79
L-Citrulline 82
Neopterin 82, 83
IL-15 79
Lecithin-Cholesterol Acyltransferase (LCAT) 33
Neuron Specific Enolase (NSE) 96
IL-17A 79
Leptin 42
Neuropeptide Y (NPY) 43 , 96
IL-17AF 79
Leukemia Inhbitory Factor 82
NGAL 43 , 82, 83 , 99, 103
IL-17F 79
Leukotriene Function (CAST®) 8 , 9, 60, 61
Nitric Oxide Synthase 1 (NOS1) 33
IL-18 79
L-FABP 102
Nitrotyrosine 33
IL-21 80
Lipoprotein 33
Norepinephrine 93 , 94, 96, 97
IL-22 80
LPL 33
Normetanephrine 94
IL-23 79, 80
Luteinizing Hormone 52
Nt-proCNP 24, 33
IL-27 80
Lysozyme 61, 62
Nucleo-h 83
IL-31 80
M
O
IL-33 81
Malondialdehyde 33
Obestatin 43
Influenza 10
Matrix Metalloproteinase (MMP) 82
Orientia Tsutsugamushi 11, 83
IL-29 80
129
Index
Osteocalcin 24
Progranulin 84
sCD137 84
Osteopontin 24, 84, 103
Proinsulin ELISA 43
sCD152/CTLA-4 85
Osteoprotegerin 24, 33
Prolactin 53
Sclero-Profile 86
Ovotransferrin 84
PSA 53 , 84, 96
Sclerostin 22, 23 , 24, 25, 44
Oxidized LDL 34
PYY 43 , 96
Secretory IgA 62, 86
OxyStat 34
130
SeroMP 86
R
Serotonin 96
P
RANTES/CCL5 84
Serum Amyloid 35, 44, 86, 96
p38 α 84
RBP 43
sE-selectin 86
p53 84
RC4d 84, 85
sFas Ligand 86
PAI-1 43 , 84
Relaxin 53
SHBG 53
Pancreatic Amylase 43
Renin 28 , 34, 35, 48 , 53
sICAM-1 86, 87
Pancreatic Polypeptide 43
Resistin 44
sL-selectin 87
PAP Complex 84
Respiratory Syncytial Virus 11
Somatostatin 44, 53
PAPP-A 52, 84
sPECAM-1 87
Parvovirus B 19 11
S
sP-selectin 87
Pepsinogen 43 , 62
s90K/Mac-2BP 84
sPSGL-1 87
Pertussis 8 , 71, 84
S100A12 62
sRANKL 25
Phospholipase 2 34
S100 ß 96
STELLUX™ 38 , 41, 44
Plasminogen 34
sAPO-1/Fas 84
sTNF-R 87
Platelet Derived Growth Factor 84
sCD23 85
sVE-cadherin 88
PMN Elastase 84
sCD26 85
Syphilis 11
Porphyrins 84
sCD28 85
PR3 ANCA 69
sCD30 85
T
Prealbumin 52, 103
sCD40 85
T4 17, 53 , 119, 120, 121
Pregnant Mare Serum Gonadotropin (PMSG) 52
sCD40L 85
TBG 54
Pregnenolone 52
sCD44std 86
Testosterone 54
Procollagen III Peptide 24, 104
sCD44var 86
Tetanus Toxin 11
Progesterone 48 , 52, 53
sCD134 84
Thyroglobulin (TG) 48, 54
TGF ß-1 88
Vasopressin (ADH/AVP) 35, 54, 125
TGF ß-2 88
Vaspin 45
Thiostatin 88
Visceral Leishmaniasis 12, 89
Thymulin 88
Vitamin A 35, 63
TIE-2 88
Vitamin B1 62, 63
TIMP-1 88
Vitamin B2 62
Tissue Transglutaminase 60, 61, 67, 71, 74
Vitamin B3 62
TNF Related Apoptosis Inducing Ligand (TRAIL) 89
Vitamin B5 63
TNF-ß 88
Vitamin B6 35, 63
TNF-α 44, 45, 88 , 89
Vitamin B9 61
Toxoplasma 11
Vitamin B12 63
Transferrin 35
Vitamin C 63
Triiodothyronine (T3) 17, 53
Vitamin D 22, 25, 48 , 58 , 63 , 100, 104
Troponin I 35, 100, 101
Vitamin E 35, 63
Tryptophan 97
Vitamin K1 25, 63
TSH 54 Type IV Collagen 104
W West Nile Virus 9, 12, 89
U Ubiquinone Coenzyme Q10 35
Z
Ureaplasma Urealyticum 12
Zonulin 63 , 89
Urocortin 97 Urotensin II 35
V Varicella Zoster 12 Vascular Adhesion Protein (sVAP-1) 87 Vascular Endothelial Growth Factor (VEGF) 89 Vasoactive Intestinal Peptide 54, 63
131
Ordering Information Index
Call today for more information or to place an order by phone. You can also submit online orders by visiting www.alpco.com.
132
Ordering Online
Orders by Phone
Please visit our website at www.alpco.com to set up
To order by phone, simply supply our Customer
an account and place an online order. ALPCO accepts
Service staff with your ALPCO customer ID number,
MasterCard, Visa and American Express. If you choose
a valid purchase order number or valid credit card, the
to set up an online account and want Terms, you will
appropriate catalog numbers and the required quantities.
be contacted by a Customer Service Associate upon placing your first order to complete a credit application.
Iodination Dates ALPCO has developed a schedule of iodination dates for
Establishing a new customer account
all radio-labeled assay kits to ensure that customers can
To establish a new customer account with Terms,
receive the freshest kits possible. This allows ALPCO
contact Customer Service to obtain a credit application.
customers to effectively plan their usage. Contact ALPCO
Completed applications can be emailed to cs@alpco.
Customer Service at cs@alpco.com or call (800)592-
com or faxed to (603)898-6854. Upon acceptance of
5726 to obtain iodination schedule information.
a completed credit application, you will be provided with an 8 character Customer I.D. number, (i.e. ALPCO=ALPCO001) for ordering purposes.
Orders by Fax Faxed orders can be sent to (603)898-6854. Be sure to include your Customer I.D. number, special instructions and price quotation when applicable to ensure proper pricing.
Information on hot deal discounts, new product promotions, and special offers can be found on the Promotions section of the ALPCO website. Order soon because supplies are limited!
Licensing and Warranty
Terms of Sale
In compliance with US Federal regulations, all
Terms of Sale are net 30 days from date of invoice. Report
customers ordering radioactive products must submit a
all incidents of shortage, breakage or any product damage
copy of the institution’s most current and valid radiation
within 5 days of receipt of goods to ALPCO at www.alpco.
license to ALPCO. This documentation will remain on
com, through our Resources/Contact Us feature or calling
file for future ordering.
(800) 592-5726. Should damage occur during shipping, please report damages to both the carrier and ALPCO.
All products manufactured and/or distributed by
ALPCO assumes no liability for loss or delay caused by
ALPCO should be used in accordance with the
conditions beyond ALPCO’s control. Report all shipping
labeled intended use. All products that are labeled
errors to ALPCO immediately. Due to the nature of the
“For Research Use Only. Not for Use in Diagnostic
products listed herein, all sales are considered final. No
Procedures.” are supplied for research applications and
consideration will be given to returns or replacements
not for use in diagnostic or clinical use. Please contact
unless prior authorization and shipping instructions have
ALPCO for current product status.
been obtained from ALPCO Customer Service.
ALPCO, it’s manufacturers and/or distributors make no
Shipping
warranties either expressed or implied concerning any
Shipping and handling charges are (FOB/EXW: Salem,
matter whatsoever, including without limitations, the
NH 03079)and prepaid and added to your invoice
condition of the product, its merchantability, or its fitness
total. ALPCO uses standard overnight service on most
for any particular use. Any modification of a test as well
domestic shipments.
as exchange or mixture of any components from different lots may influence results, and cannot be supported.
133
ALPCO 26-G Keewaydin Drive Salem, NH 03079
Phone: 800-592-5726 Fax: 603-898-6854 cs@alpco.com
www.alpco.com 2013–2014