GARLAND SCIENCE CATALOG 2014 www.garlandscience.com
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CONTENTS
Cell & Molecular Biology........1 Genetics...........................6 Microbiology.....................11 ASM Press ........................14 Immunology.....................22 Structural Biology...............26 Biophysics........................29 Computational Biology.........31 Chemistry....................... 33 Plant and Marine Biology......26 BIOS Instant Notes Series..... 34 Title Index.......................38 Author Index.....................39 Order Form......................40
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CELL & MOLECULAR BIOLOGY
1
NEW EDITION Essential Cell Biology, Fourth Edition Bruce Alberts, University of California, San Francisco, USA, Dennis Bray, University of Cambridge, UK, Karen Hopkin, Science Journalist and Biochemist, USA, Alexander Johnson, University of California, San Francisco, USA, Julian Lewis, Emeritus Scientist at Cancer Research UK, Martin Raff, University College London, UK, Keith Roberts, Emeritus, University of East Anglia, UK, and Peter Walter, University of California, San Francisco, USA
Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition. Garland Science October 2013: 865pp: 860 illus Hb: 978-0-8153-4454-4: £105.00 Pb: 978-0-8153-4455-1: £53.00
CONTENTS: 1. Cells: The Fundamental Units of Life 2. Chemical Components of Cells 3. Energy, Catalysis, and Biosynthesis 4. Protein Structure and Function 5. DNA and Chromosomes 6. DNA Replication, Repair, and Recombination 7. From DNA to Protein: How Cells Read the Genome 8. Control of Gene Expression 9. How Genes and Genomes Evolve 10. Modern Recombinant DNA Technology 11. Membrane Structure 12. Transport Across Cell Membranes 13. How Cells Obtain Energy from Food 14. Energy Generation in Mitochondria and Chloroplasts 15. Intracellular Compartments and Protein Transport 16. Cell Signaling 17. Cytoskeleton 18. The Cell Division Cycle 19. Sexual Reproduction and the Power of Genetics 20. Cellular Communities: Tissues, Stem Cells, and Cancer
“
Praise for previous edition
NEW TO THE FOURTH EDITION: • Comprehensive scientific update of the entire text and figures in the book. • New material on regulatory RNAs, epigenetics, induced pluripotent stem cells, cell suicide and reprogramming, the human genome, and our surprising inheritance from Neanderthals. • Based on extensive student feedback, improved discussion and new figures of photosynthesis, metabolism, and DNA repair. • Updated coverage of many exciting, new experimental techniques including RNAi, optogenetics, the applications of new DNA sequencing technologies, and the use of mutant organisms to probe the defects underlying human disease. • Medically relevant topics include new sections on culturing human cells for clinical work, autism and iPS cells, peroxisomes and disease, cancer changes in key regulatory pathways, as well as expanded coverage of amyloid proteins and their role in Alzheimer’s and Huntington’s diseases, the use of genome sequencing to identify the rare mutations that predispose us to disease, and much more. • New and enhanced student self-assessments available online.
[Essential Cell Biology] really ought to be an intrinsic part of every bioscience undergraduate's essential reading.
”
The Biochemist
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2
CELL & MOLECULAR BIOLOGY
NEW EDITION Molecular Biology of the Cell, Sixth Edition Bruce Alberts, University of California, San Francisco, USA, Alexander Johnson, University of California, San Francisco, USA, Julian Lewis, Emeritus Scientist at Cancer Research UK, David Morgan, University of California, San Francisco, USA, Martin Raff, University College London, UK, Keith Roberts, Emeritus, University of East Anglia, UK, and Peter Walter, University of California, San Francisco, USA
Continuing its tradition of excellence in cell biology education, the Sixth Edition of Molecular Biology of the Cell will be published in late 2014. As the amount of information in biology expands exponentially, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts. As with previous editions, MBoC6 accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced. Protein structures better illustrate structure-function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing open-ended questions highlighting “what we don’t know,” introducing students to challenging areas of future research. Updated end-ofchapter problems reflect new research discussed in the text. New questions on developmental biology, tissues and stem cells, the immune system, and pathogens are added to the final four chapters. Some major changes include: • Describes powerful new methods that scientists use to analyze genes and proteins, and to better visualize subcellular structures. • Explains new functions discovered for RNA molecules. • Includes the latest findings on the structure and function of the human genome. • Emphasizes the need for mathematics to unravel the complexities of cell function, with a section added to Chapter 8: Analyzing Cells, Molecules, and Systems that is echoed throughout the book. • Explains new insights on how low-complexity protein sequences help to organize the interior of cells. • Focuses on the fundamental concepts in cellular signaling, with emphasis on key principles underlying the circuitry of signaling systems. • Covers new insights into the causes, genetics, and treatments of cancer—including a discussion of personalized therapy—in a completely reorganized Chapter 20: Cancer. • Adds new sections on timing, growth control, and morphogenesis to Chapter 21: Animal Development. • Features an extensively revised and expanded treatment of stem cell molecular biology and technology—including cloning, nuclear reprogramming, ES cells, and iPS cells. Garland Science December 2014: 1,416pp: 1,550 illus Hb: 978-0-8153-4432-2: £125.00 Pb: 978-0-8153-4464-3: £69.00
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CELL & MOLECULAR BIOLOGY
3
Molecular Biology of the Cell, Sixth Edition CONTENTS: INTRODUCTION TO THE CELL 1. Cells & Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins BASIC GENETIC MECHANISMS 4. DNA and Chromosomes 5. DNA Replication, Repair, and Recombination 6. How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expression WAYS OF WORKING WITH CELLS 8. Analyzing Cells, Molecules, and Systems 9. Visualizing Cells INTERNAL ORGANIZATION OF THE CELL 10. Membrane Structure 11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes
Praise for the Fifth Edition
“
A quarter of a century after the first edition revolutionized cell biology textbooks, the new edition is as fresh, comprehensive and above all, as readable as ever.
”
British Society for Developmental Biology Newsletter
12. Intracellular Compartments & Protein Sorting 13. Intracellular Vesicular Traffic 14. Energy Conversion: Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17. The Cell Cycle 18. Programmed Cell Death CELLS IN THEIR SOCIAL CONTEXT 19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix 20. Cancer 21. Animal Development 22. Stem Cells and Tissue Renewal 23. Pathogens and Infection 24. The Innate and Adaptive Immune Systems
“
MBoC has only improved over its several editions, growing with the rapid advances in the field to become an essential resource for students at all levels and a trusted first stop for researchers transitioning into unfamiliar areas of cell biology….the MBoC5 package is a fantastic resource and well worth the upgrade.
Molecular Biology of the Cell: The Problems Book Sixth Edition
”
Development
John Wilson, Baylor College of Medicine, USA, and Tim Hunt, Cancer Research UK
The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms, test for understanding basic concepts, and pose research based problems. The Problems Book has been designed to correspond with the first twenty chapters of Molecular Biology of the Cell, Sixth Edition. Garland Science December 2014: 608pp: 826 illus Pb: 978-0-8153-4453-7: £29.00
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4
CELL & MOLECULAR BIOLOGY
The Biology of Cancer, Second Edition Robert A. Weinberg, Whitehead Institute for Biomedical Research, MIT, USA
Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology. Praise for previous edition
Garland Science May 2013: 960pp: 584 illus Hb: 978-0-8153-4219-9: £110.00 Pb: 978-0-8153-4220-5: £60.00
“
The Biology of Cancer is no doubt the definitive statement on its topic today. Science
”
CONTENTS: 1. The Biology and Genetics of Cells and Organisms 2. The Nature of Cancer 3. Tumor Viruses 4. Cellular Oncogenes 5. Growth Factors, Receptors, and Cancer 6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer 7. Tumor Suppressor Genes 8. pRb and Control of the Cell Cycle Clock 9. p53 and Apoptosis: Master Guardian and Executioner 10. Eternal Life: Cell Immortalization and Tumorigenesis 11. Multistep Tumorigenesis 12. Maintenance of Genomic Integrity and the Development of Cancer 13. Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis 14. Moving Out: Invasion and Metastasis 15. Crowd Control: Tumor Immunology and Immunotherapy 16. The Rational Treatment of Cancer
Biology of Aging Roger McDonald, University of California at Davis, USA
Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and longevity and describes how these basic principles help one to understand the uniquely human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. CONTENTS: 1. Basic Concepts in the Biology of Aging 2. Measuring Biological Aging 3. Evolutionary Theories of Longevity and Aging 4. Cellular Aging 5. Genetics of Longevity 6. Plant Senescence 7. Human Longevity 8. The Physiology of Human Aging 9. Age-Related Disease in Humans 10. Modulating Aging and Longevity
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Garland Science July 2013: 360pp: 241 illus Pb: 978-0-8153-4213-7: £42.00
CELL & MOLECULAR BIOLOGY
5
NEW
Cell Signaling
Wendell Lim, University of California San Francisco, USA, Bruce Mayer, University of Connecticut Health Center, USA, and Tony Pawson (deceased)
Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods. CONTENTS: 1. Overview of Signal Transduction 2. Principles and Mechanisms of Protein Interactions 3. Signaling Enzymes and Their Allosteric Regulation 4. Role of Post-Translational Modifications in Signaling 5. Subcellular Localization of Signaling Molecules 6. Small Soluble Signaling Mediators 7. Lipids and Enzymes that Modify Them 8. Information Transfer Across the Membrane 9. Regulated Protein Degradation 10. Modular Architecture and Evolution of Signaling Proteins 11. Signaling Devices in Networks 12. How Cells Make Decisions 13. Methods for Studying Signaling Proteins and Networks Garland Science July 2014: 368pp: 340 illus Pb: 978-0-8153-4244-1: £44.00
Cellular Signal Processing
An Introduction to the Molecular Mechanisms of Signal Transduction
Friedrich Marks, Ursula Klingmüller and Karin Müller-Decker, all at University of Heidelberg and the German Cancer Research Center, Germany
Cellular Signal Processing is for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. Garland Science 2008: 656pp: 428 illus Pb: 978-0-8153-4215-1: £50.00
“
Unlike other texts currently available, a common theme of data processing by cellular machinery runs through this book which makes it stand out favorably against the competition.
”
Alexey Veraksa University of Massachusetts, USA
CONTENTS: 1. The “Brain of the Cell”: Data Processing by Protein Networks 2. Supplying the Network with Energy: Basic Biochemistry of Signal Transduction 3. Evolution of Cellular Data Processing 4. Basic Equipment: G-Proteins, Second Messengers, and Protein Kinases 5. Signal Transduction by Receptors with Seven Transmembrane Domains 6. Signal Transduction by Serine/Threonine Kinase-Coupled Receptors 7. Signal Transduction by Tyrosine Kinase- and Protein PhosphataseCoupled Receptors: A Late Invention of Evolution 8. Gene Transcription: The Ultimate Target of Signal Transduction 9. Signals Controlling mRNA Translation 10. Signal Transduction by Small G-proteins: The Art of Molecular Targeting 11. Mitogenactivated Protein Kinase and Nuclear Factor kB Modules 12. Cancer and Regulation of Cell Division 13. Signal Transduction by Proteolysis and Programmed Cell Death 14. Signal Transduction by Ions 15. Sensory Signal Processing 16. Signaling at Synapses: Neurotransmitters and Their Receptors 17. Putting Together the Pieces: The Approach of Systems Biology
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6
GENETICS
Human Evolutionary Genetics, Second Edition Mark Jobling and Edward Hollox, both at University of Leicester, UK, Toomas Kivisild, University of Cambridge, UK, Chris Tyler-Smith and Matthew Hurles, both at Wellcome Trust Sanger Institute, UK
Now in full color, the Second Edition of Human Evolutionary Genetics has been completely revised to cover the rapid advances in the field since the publication of the highly regarded First Edition. Written for upper-level undergraduate and graduate students, it is the only textbook to integrate genetic, archaeological, and linguistic perspectives on human evolution, and to offer a genomic perspective, reflecting the shift from studies of specific regions of the genome towards comprehensive genomewide analyses of human genetic diversity. Human Evolutionary Genetics is suitable for courses in Genetics, Evolution, and Anthropology. Garland Science June 2013: 650pp: 357 illus Pb: 978-0-8153-4148-2: £52.00 CONTENTS: 1. An Introduction to Human Evolutionary Genetics Section I: How Do We Study Genetic Variation? 2. Organization and Inheritance of the Human Genome 3. Human Genome Variation 4. Finding and Assaying Genome Diversity Section II: How Do We Interpret Genetic Variation? 5. Processes Shaping Diversity 6. Making Inferences from Diversity Section III: Where and When Did Humans Originate? 7. Humans as Apes 8. What Genetic Changes Have Made Us Human? 9. Origins of Modern Humans Section IV: How Did Humans Colonize the World? 10. The Distribution of Diversity 11. The Colonization of the Old World And Australia 12. Agricultural Expansions 13. Into New Found Lands 14. What Happens When Populations Meet? Section V: How Is An Evolutionary Perspective Helpful? 15. Understanding the Past, Present and Future of Phenotypic Variation 16. Evolutionary Insights into Simple Genetic Diseases 17. Evolution and Complex Diseases 18. Identity and Identification
Human Molecular Genetics, Fourth Edition
Tom Strachan, Newcastle University, UK, and Andrew Read, University of Manchester, UK
Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. Garland Science 2010: 781pp: 610 illus Pb: 978-0-8153-4149-9: £52.00
“
This book is an excellent companion for students in human genetics or for researchers that want to gain background and knowledge in this field.
” Nature
CONTENTS: 1. Nucleic Acid Structure and Gene Expression 2. Chromosome Structure and Function 3. Genes in Pedigrees and Populations 4. Cells and Cell-Cell Communication 5. Principles of Development 6. Amplifying DNA: Cell-based DNA Cloning and PCR 7. Nucleic Acid Hybridization: Principles and Applications 8. Analyzing the Structure and Expression of Genes and Genomes 9. Organization of the Human Genome 10. Model Organisms, Comparative Genomics and Evolution 11. Human Gene Expression 12. Studying Gene Function in the Post-Genome Era 13. Human Genetic Variability and its Consequences 14. Genetic Mapping of Mendelian Characters 15. Mapping Genes Conferring Susceptibility to Complex Disease 16. Identifying Human Disease Genes and Susceptibility Factors 17. Cancer Genetics 18. Genetic Testing of Individuals 19. Pharmacogenetics, Personalized Medicine, and Population Screening 20. Genetic Manipulation of Animals for Modeling Disease and Investigating Gene Function 21. Genetic Approaches to Treating Disease
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GENETICS
7
NEW
Genetics and Genomics in Medicine Tom Strachan, Judith Goodship, Patrick Chinnery, all at Newcastle University, UK
This new textbook explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Other new advances, such as the role of RNA and epigenetics are also included. The discussion on genetic approaches to treatment includes pharmacogenomics and the prospects for personalized medicine. Cancer is essentially a genetic disease and is given a dedicated chapter. There are extensive questions and problems for each chapter and clinical disorder boxes throughout. Garland Science April 2014: 500pp: 270 illus Pb: 978-0-8153-4480-3: ÂŁ46.00 CONTENTS: 1. Fundamentals of DNA, Chromosomes and Cells. 2. Fundamentals of Gene Structure, Gene Expression and Human Genome Organization 3. Principles Underlying Core DNA Technologies 4. Principles of Genetic Variation 5. Single Gene Disorders: Inheritance Patterns, Phenotype Variability and Allele Frequencies 6. Principles of Gene Regulation and Epigenetics 7. Disease-Causing Abnormalities in DNA and Chromosomes 8. Identifying Disease Genes and Genetic Susceptibility to Common Disease 9. Genetic Approaches to Treating Disease 10. Cancer Genetics 11. Genetic Testing and the Developing Impact of Genetics in Medicine
Epigenetics
Lyle Armstrong, Newcastle University, UK
Epigenetics is a new textbook that brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It is a valuable source of information about all aspects of the subject for undergraduate students, graduate students, and professionals. Garland Science November 2013: 300pp: 150 illus Pb: 978-0-8153-6511-2: ÂŁ45.00 CONTENTS: 1. Introduction to the Study of Epigenetics 2. The Basis of the Transcription Process 3. DNA Packaging and Chromatin Architecture 4. Modifying the Structure of Chromatin 5. DNA Methylation 6. Post-translational Modification of Histones 7. Histone Modification Machinery 8. Locus-Specific Control of Histone-Modifying Enzyme Action 9. Epigenetic Control of Cell-Specific Gene Expression 10. Epigenetic Control of the Mitotic Cell Cycle 11. The Epigenetic Basis of Gene Imprinting 12. Epigenetic Control of Cellular Differentitation 13. Reversibility of Epigenetic Modification Patterns 14. Epigenetic Predisposition to Disease and Imprinting-Based Disorders 15. Epigenetics of Memory, Neurodegeneration, and Mental Health 16. Epigenetics of Cancer
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8
GENETICS
Genome Stability DNA Repair and Recombination James E. Haber, Brandeis University, USA
Genome Stability: DNA Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An overview of the four major pathways of homologous recombinational repair is followed by a description of the several mechanisms of nonhomologous end-joining. Designed as a textbook for advanced undergraduate and graduate students with a molecular biology and genetics background, researchers and practitioners, especially in cancer biology, will also appreciate the book as a reference. Garland Science December 2013: 320pp: 313 illus Pb: 978-0-8153-4485-8: £50.00 CONTENTS: 1. Restarting DNA Replication by Recombination 2. Double-strand Break Repair Pathways 3. RecA/Rad51 and the Search for Homology 4. Preparation of the RecA/Rad51 Filament 5. Single-Strand Annealing 6. Gene Conversion 7. In vivo Biochemistry: Recombination in Yeast 8. Break-induced Replication 9. Sister Chromatid Repair 10. Gene Targeting 11. Site-specific Recombination 12. Cytology and Genetics of Meiosis 13. Molecular Events During Meiotic Recombination 14. Holliday Junction Resolvases and Crossing-over 15. Nonhomologous End-joining 16. DNA Damage Checkpoints and Genome Instability Appendix Evolution of Models of Homologous Recombination
Gene Control David S. Latchman, Birkbeck, University of London, UK
Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition.
Garland Science 2010: 448pp: 638 illus Pb: 978-0-8153-6513-6: £53.00 CONTENTS: 1. Levels of Gene Control 2. Structure of Chromatin 3. Role of Chromatin Structure in Gene Control 4. The Process of Transcription 5. Transcription Factors and Transcriptional Control 6. Post-transcriptional Processes 7. Post-transcriptional Regulation 8. Gene Control and Cellular Signaling Pathways 9. Gene Control in Embryonic Development 10. Control of Cell-type-specific Gene Expression 11. Gene Regulation and Cancer 12. Gene Regulation and Human Disease 13. Conclusions and Future Prospects
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GENETICS
9
Genome Duplication Melvin DePamphilis, National Institute of Child Health and Human Development, USA, and Stephen Bell, University of Oxford, UK
Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism. Garland Science 2010: 450pp: 243 illus Pb: 978-0-415-44206-0: £57.00
“
CONTENTS: 1. Genomes 2. Life 3. Replication Forks 4. Replication Proteins: Leading Strand Synthesis 5. Replication Proteins: Lagging Strand Synthesis 6. Termination 7. Chromatin Assembly Cohesion and Modification 8. Replicons 9. Replication Origins 10. Origin Paradigms 11. Initiation 12. Cell Cycles 13. Checkpoints 14. Human Disease 15. Evolution of Cellular Replication Machineries
This book is an excellent reference for anyone who is interested in understanding the fundamentals of life. Summing up: Highly recommended.
”
C.A Klevickis James Madison University, USA
Genomes 3 Terry A. Brown, University of Manchester, UK
The pioneering textbook Genomes put genomes, rather than genes, at the center of molecular genetics teaching. Genomes 3 provides the reader with a simple and elegant treatment of the field, covering molecular genetics from the basics through to genome expression and molecular phylogenetics. Garland Science 2006: 736pp: 550 illus Pb: 978-0-8153-4138-3: £57.00
“
...Genomes 3 is a useful book about molecular genetics and will no doubt be competing for the attention of students...
”
Bioscience Education Journal
CONTENTS: Part 1: Studying Genomes 1. Genomes, Transcriptomes and Proteomes 2. Studying DNA 3. Mapping Genomes 4. Sequencing Genomes 5. Understanding a Genome Sequence 6. Understanding How a Genome Functions Part 2: Genome Anatomies 7. Eukaryotic Nuclear Genomes 8. Genomes of Prokaryotes and Eukaryotic Organelles 9. Virus Genomes and Mobile Genetic Elements Part 3: How Genomes Function 10. Accessing the Genome 11. Assembly of the Transcription Initiation Complex 12. Synthesis and Processing of RNA 13. Synthesis and Processing of the Proteome 14. Regulation of Genome Activity Part 4: How Genomes Replicate and Evolve 15. Genome Replication 16. Mutations and DNA Repair 17. Recombination 18. How Genomes Evolve 19. Molecular Phylogenetics
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10 GENETICS
NEW EDITION
Introducing Genetics, Second Edition From Mendel to Molecules
Alison Thomas, Anglia Ruskin University, UK
The new edition of Introducing Genetics is a clear, concise, and accessible guide to inheritance and variation in individuals and populations. It first establishes the principles of Mendelian inheritance and the nature of chromosomes, before tackling quantitative and population genetics. The final three chapters introduce the molecular mechanisms that underlie genetics, including the techniques responsible for the current genetic revolution. As genetics affects all living organisms, examples are taken from insects, plants, animals, and humans. Each chapter ends with a set of problems to help the reader develop their understanding of genetics. CONTENTS: 1. Introduction 2. Monohybrid Inheritance 3. Extensions to Monohybrid Inheritance 4. Dihybrid Inheritance 5. The Chromosomal Basis of Inheritance 6. Sex Determination and Sex Linkage 7. Linkage and Chromosome Mapping 8. Variation in Chromosomal Number and Structure 9. The Principles of Quantitative Genetics 10. An Introduction to Population Genetics 11. Heredity at the Molecular Level 12. From Genes to Proteins 13. Manipulating DNA Garland Science November 2014: 250pp: 150 illus Pb: 978-0-8153-4509-1: £20.00
Introduction to Genetics A Molecular Approach
Terry A. Brown, University of Manchester, UK
The theme of Introduction to Genetics is the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms, and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. Garland Science 2011: 538pp: 656 illus Pb: 978-0-8153-6509-9: £51.00
“
The progression from molecules through processes to systems makes eminenet sense to a clear visual style similar to the one used for Genomes 3 should make this an attractive proposition for adoption.
Adrian Hall Sheffield Hallam University, UK
”
CONTENTS: PART 1 - GENES AS UNITS OF BIOLOGICAL INFORMATION 1. The Scope of Modern Genetics 2. DNA 3. Genes 4. Transcription of DNA to RNA 5. Types of RNA Molecule: Messenger RNA 6. Types of RNA Molecule: Noncoding RNA 7. The Genetic Code 8. Protein Synthesis 9. Control of Gene Expression PART 2 - GENES AS UNITS OF INHERITANCE 10. DNA Replication 11. Inheritance of Genes During Eukaryotic Cell Division 12. Inheritance of Genes in Bacteria 13. Inheritance of Genes During Virus Infection Cycles 14. Inheritance of DNA Molecules During Eukaryotic Sexual Reproduction 15. Inheritance of Genes During Eukaryotic Sexual Reproduction 16. Mutation and DNA repair 17. Inheritance of genes in Populations PART 3 - GENETICS IN OUR MODERN WORLD 18. Genes in Differentiation and Development 19. The Human Genome 20. Genes and Medicine 21. DNA in Forensics and Studies of Human History 22. Genes in Industry and Agriculture 23. The Ethical Issues Raised by Modern Genetics
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MICROBIOLOGY 11 Microbiology
A Clinical Approach Anthony Strelkauskas (deceased), Jennifer Strelkauskas, Doctor of Veterinary Medicine, Oregon, USA, and Danielle Moszyk-Strelkauskas, MD, Naval Medical Center, San Diego, USA
Microbiology: A Clinical Approach is a unique microbiology textbook for health science students studying microbiology. It is clinically-relevant and uses the theme of infection as its foundation.
“
...extensively illustrated throughout with photographs and easy to understand schematics. It is well-supported by a website for students including an E-Tutor, MicroMovies (to demonstrate flagellar movement for example), flashcards and lecture notes.
”
Garland Science 2010: 733pp: 630 illus Pb: 978-0-8153-6514-3: £52.00
The Biologist
CONTENTS: PART I FOUNDATIONS 1. What is Microbiology and Why Does it Matter? 2. Fundamental Chemistry for Microbiology 3. Essentials of Metabolism 4. An Introduction to Cell Structure and Host–Pathogen Relationships PART II DISEASE MECHANISMS 5. Requirements for Infection 6. Transmission of Infection, the Compromised Host, and Epidemiology 7. Principles of Disease 8. Emerging and Re-Emerging Infectious Diseases PART III CHARACTERISTICS OF DISEASE-CAUSING MICROORGANISMS 9. The Clinical Significance of Bacterial Anatomy 10. Bacterial Growth 11. Microbial Genetics and Infectious Disease 12. The Structure and Infection Cycle of Viruses 13. Viral Pathogenesis 14. Parasitic and Fungal Infections PART IV HOST DEFENSE 15. The Innate Immune Response 16. The Adaptive Immune Response 17. Failures of the Immune Response PART V CONTROL AND TREATMENT 18. Control of Microbial Growth with Disinfectants and Antiseptics 19. Antibiotics 20. Antibiotic Resistance PART VI MICROBIAL INFECTIONS 21. Infections of the Respiratory System 22. Infections of the Digestive System 23. Infections of the Genitourinary System 24. Infections of the Central Nervous System 25. Infections of the Blood 26. Infections of the Skin and Eyes PART VII THE BEST AND THE WORST; IMPORTANT ISSUES IN MICROBIOLOGY 27. Biotechnology 28. Bioterrorism
Viruses
Biology, Applications, and Control David R. Harper, Biocontrol Limited, UK
Viruses: Biology, Applications, and Control is a concise advanced undergraduate and graduate textbook covering the essential aspects of virology included in biomedical science courses. It is an updated and expanded version of David Harper’s Molecular Virology, Second Edition. Garland Science 2011: 346pp: 220 illus Pb: 978-0-8153-4150-5: £48.00
“
CONTENTS: 1. Virus Structure and Infection 2. Virus Classification and Evolution 3. Virus Replication 4. Immune Response and Evasion 5. Vaccines and Immunotherapy 6. Antiviral Drugs 7. Beneficial Use of Viruses 8. Emergence and Extinction of Viruses 9. Virus Culture, Detection and Diagnosis
...a good text for an advanced undergraduate course in virology.
”
Doodys Review
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12 MICROBIOLOGY Living in a Microbial World Bruce V. Hofkin, University of New Mexico, USA
Living in a Microbial World is a textbook written for students taking a general microbiology or microbiology-themed course for non-science majors. It teaches the essential concepts of microbiology through practical examples and a conversational writing style intended to make the material accessible to a wide audience. Garland Science 2010: 496pp: 413 illus Pb: 978-0-8153-4175-8: £47.00
“
It is a treasure trove of interesting anecdotes and facts which lecturers could use to spice up their lectures, or whet the appetite for more microbiology in keen students.
”
Immunology News CONTENTS: 1. Living in a Microbial World 2. The Chemistry of Life 3. The Cell: Where Life Begins 4. A Field Guide to the Microorganisms 5. The Microbiology of History and the History of Microbiology 6. An Introduction to Microbial Genetics 7. Microbial Metabolism and Growth 8. Microbial Evolution and the Origin of Life 9. An Ecologist’s Guide to Microbiology 10. The Disease Process: A Pathogen’s Perspective 11. Host Defense 12. Control of Microbial Growth 13. Epidemiology: Who, What, When, Where, and Why? 14. The Future is Here: Microorganisms and Biotechnology 15. Guess Who’s Coming to Dinner? Microorganisms and Food 16. Better Living with Microorganisms: Industrial and Applied Microbiology
Protozoa and Human Disease Mark F. Wiser, Tulane University, USA
Protozoa and Human Disease is a textbook for advanced undergraduate and graduate students studying parasitology and microbiology. It will also be a useful reference for public health and medical students. Garland Science 2010: 250pp: 113 illus Pb: 978-0-8153-6500-6: £41.00
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...gives a clear overview of the medically most relevant protozoa...it has just the right size for detailed information without being overwhelming.
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Immunology News
Email us at garlanduk@tandf.co.uk
CONTENTS: 1. Introduction to Medical Protozoology 2. Overview of Intestinal Protozoa 3. Entamoeba and Amebiasis 4. Giardiasis 5. Trichomonas vaginalis and Other Trichomonads 6. Balantidium coli and Blastocystis hominis 7. Kinetoplastids 8. African Trypanosomiasis 9. Trypanosoma cruzi and Chagas’ Disease 10. Leishmaniasis 11. General Apicomplexan Biology 12. Cryptosporidium 13. Monoxenous Intestinal Coccidia 14. Toxoplasma gondii 15. Malaria 16. Babesiosis 17. Free-Living Protozoa Affecting Human Health
MICROBIOLOGY 13 Case Studies in Infectious Disease Peter Lydyard, Royal Free and University College Medical School, UK, Michael Cole, Georgetown University Medical Center, USA, John Holton, Royal Free and University College Medical School, UK, Will Irving, University of Nottingham, UK, Nino Porakishvili, University of Westminster, UK, Pradhib Venkatesan, Nottingham University Hospital, UK, and Kate Ward, Royal Free and University College Medical School, UK
Case Studies in Infectious Disease presents forty case studies featuring the most important human infectious diseases worldwide. Written for students of microbiology and medicine, this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis and treatment. Garland Science 2009: 608pp: 270 illus Pb: 978-0-8153-4142-0: £38.00
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It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers.
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Clinical Infectious Disease
CONTENTS: 1. Aspergillus fumigatus 2. Borellia burgdorferi and related species 3. Campylobacter jejuni 4. Chlamydia trachomatis 5. Clostridium difficile 6. Coxiella burnetti 7. Coxsackie B virus 8. Echinococcus spp. 9. Epstein-Barr virus 10. Escherichia coli 11. Giardia lamblia 12. Helicobacter pylori 13. Hepatitis B virus 14. Herpes simplex virus 1 15. Herpes simplex virus 2 16. Histoplasma capsulatum 17. Human immunodeficiency virus 18. Influenza virus 19. Leishmania spp. 20. Leptospira spp. 21. Listeria monocytogenes 22. Mycobacterium leprae 23. Mycobacterium tuburculosis 24. Neisseria gonorrhoeae 25. Neisseria meningitidis 26. Norovirus 27. Parvovirus 28. Plasmodium spp. 29. Respiratory syncytial virus 30. Rickettsia spp. 31. Salmonella typhi 32. Schistosoma spp. 33. Staphlococcus aureus 34. Streptococcus mitis 35. Streptococcus pneumoniae 36. Streptococcus pyogenes 37. Toxoplasma gondii 38. Trypanosoma spp. 39. Varicella-zoster virus 40. Wuchereria bancrofti
Biology of Disease Nessar Ahmed, Maureen Dawson, Chris Smith, all at Manchester Metropolitan University, UK, and Ed Wood (deceased)
Biology of Disease describes the biology of many of the human disorders and diseases that are encountered in a clinical setting. It is designed for first and second year students in biomedical science programs and will also be a highly effective reference for health science professionals.
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Taylor & Francis 2006: 600pp Pb: 978-0-7487-7210-0: £42.00
...this book is an excellent introduction to the subject of pathology, disease and laboratory diagnostics, which would be ideal for undergraduate students on biomedical science and related degrees.
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Alison Cottell University of Surrey, UK
CONTENTS: Preface • Glossary 1. The Nature and Investigation of Diseases 2. Pathogens and Virulence 3. Infectious Diseases and Treatments 4. The Immune System 5. Disorders of the Immune System 6. Transfusion and Transplantation 7. Disorders of the Endocrine System 8. Disorders of Water, Electrolytes and Urate Balances 9. Disorders of AcidBase Balance 10. Diet and Disease 11. Disorders of the Gastrointestinal Tract, Pancreas, Liver and Gall Bladder 12. Toxicology 13. Disorders of the Blood 14. Disease of the Cardiovascular System 15. Genetic Diseases 16. Membrane, Organelle and cytoskeletal Disorders 17. Cancer 18. Aging & Disease • Case Study Discussions • Answers to Questions
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14 AMERICAN SOCIETY FOR MICROBIOLOGY PRESS Taylor and Francis is pleased to announce its appointment as exclusive distributor for the American Society for Microbiology Press in the UK and ROW (excluding North, Central, and South America), taking effect from 1st January 2014. The American Society for Microbiology Press publishes books on diverse topics, with special emphasis on the field of microbiology. They are suitable for students and professionals, as well as those with a general interest in microbiology. Pages 14-20 of this catalog showcase their best-sellers, along with titles publishing in 2014. For the full list of ASM Press titles visit our website at www.garlandscience. com. Contact us at garlanduk@tandf.co.uk with any questions about the titles in this catalog or those featured on the website.
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AMERICAN SOCIETY FOR MICROBIOLOGY PRESS
15
TOP TEN BESTSELLERS Molecular Genetics of Bacteria, 4th Edition Larry Snyder, Michigan State University, USA; Joseph E. Peters, Cornell University, USA; Tina M. Henkin, Ohio State University, USA; and Wendy Champness, Michigan State University, USA The classic comprehensive and authoritative textbook on bacterial molecular genetics. American Society for Microbiology Press January 2013: 728pp: HB 978-1-5558-1627-8: £89.00
Manual of Clinical Microbiology, 10th Edition, 2 Volume Set Editor-in-Chief: James Versalovic, Texas Children’s Hospital and Baylor College of Medicine, USA The Manual of Clinical Microbiology continues to set the standard for state-of-the-science laboratory practice as the most authoritative reference in the field. American Society for Microbiology Press May 2011: 2,630pp: HB 978-1-5558-1463-2: £194.00
Principles of Virology, 3rd Edition, 2 Volume Set S. Jane Flint, Princeton University, USA; Lynn W. Enquist, Princeton University, USA; Vincent R. Racaniello, Columbia University, USA; and Anna Marie Skalka, Fox Chase Cancer Center, USA Best-selling textbook fills the gap between introductory texts and advanced reviews of major virus families. American Society for Microbiology Press January 2009: 986pp: PB Set: 978-1-5558-1443-4: £117.00 Volume I: Molecular Biology : PB 978-1-5558-1479-3: £69.00 Volume II Pathogenesis and Control : PB 978-1-5558-1480-9: £69.00
Food Microbiology: Fundamentals and Frontiers 4th Edition Michael P. Doyle, University of Georgia, USA, and Robert L. Buchanan, University of Maryland, USA This essential reference emphasizes the molecular and mechanistic aspects of food microbiology in one comprehensive volume. American Society for Microbiology Press May 2011: 1500pp: HB 978-1-5558-1626-1: £144.00
Color Atlas of Medical Bacteriology, 2nd Edition Luis M. de la Maza, Marie T. Pezzlo, Janet T. Shigei, Grace L. Tan, and Ellena M. Peterson, University of California, Irvine, USA A unique visual reference for the diagnostic microbiology laboratory. American Society for Microbiology Press May 2013: 342pp: HB 978-1-5558-1475-5: £122.00
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16 AMERICAN SOCIETY FOR MICROBIOLOGY PRESS Medically Important Fungi, 5th Edition A Guide to Identification Davise H. Larone, Weill Medical College of Cornell University, USA The tool you need to confidently and accurately identify clinically relevant fungi. American Society for Microbiology Press September 2011: 485pp: HB 978-1-5558-1660-5: £79.00
Clinical Microbiology Procedures Handbook, 3rd Edition Lynne S. Garcia, LSG and Associates, USA A collaborative effort of over 150 clinical microbiologists, medical laboratory technologists, and laboratory supervisors. American Society for Microbiology Press Loose Leaf Binder Set May 2010: 2,540pp: 978-1-5558-1527-1: £180.00
Food Microbiology: An Introduction, 3rd Edition Thomas J. Montville, Karl R. Matthews, both at Rutgers University, USA and Kalmia E. Kniel, University of Delaware, USA This textbook presents authoritative coverage in a format designed to facilitate teaching and learning. American Society for Microbiology Press June 2012: 570pp: HB 978-1-5558-1636-0: £75.00
Molecular Biotechnology, 4th Edition Bernard R. Glick, University of Waterloo, Ontario, Canada; Jack J. Pasternak, Emeritus, University of Waterloo, Ontario, Canada; and Cheryl L. Patten, University of New Brunswick, USA A unique, adaptable textbook for upper-level undergraduate and graduate courses emphasizing particular aspects of modern biotechnology. American Society for Microbiology Press December 2009: 850pp: HB 978-1-5558-1498-4: £82.00
Virology: Molecular Biology and Pathogenesis Leonard Norkin, University of Massachusetts, USA Enables students and professionals to develop a deep understanding of fundamental virology by emphasizing principles and discussing viruses organized by virus family. American Society for Microbiology Press November 2009: 750pp: HB 978-1-5558-1453-3: £103.00
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AMERICAN SOCIETY FOR MICROBIOLOGY PRESS
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NEW EDITION Clinical Laboratory Management, 2nd Edition Editor in Chief: Lynne S. Garcia, LSG and Associates, USA
This extensively revised Second Edition is a comprehensive volume presenting authoritative information on the management challenges facing today’s clinical laboratories. Key Features: • Provides thorough coverage of management topics such as managerial leadership, personnel, business planning, information management, regulatory management, reimbursement, generation of revenue, and more. • Includes valuable administrative resources, including checklists, worksheets, forms, and online resources. • Serves as an essential resource for all clinical laboratories, from the physician’s office to hospital clinical labs to the largest commercial reference laboratories, providing practical information in the fields of medicine and healthcare, clinical pathology, and clinical American Society for Microbiology Press January 2014 laboratory management, for practitioners, managers, and HB: 978-1-5558-1727-5: £108.00 individuals training to enter these fields. Reference Manual
One Health: People, Animals and the Environment Edited by Ronald M. Atlas, University of Louisville, USA, and Stanley Maloy, San Diego State University, USA
The One Health initiative was born of the perception that veterinarians working on diseases of animals, plant pathologists working on diseases of plants, and microbiologists and infectious diseases professionals working on emerging diseases and outbreaks in humans were often working on similar problems or only part of the larger picture. If humans are to be healthy, they must live in a healthy environment. This book presents the concepts of the One Health Initiative to a wide audience of scientists, professionals, and the general public. Written by scientists working in the field, this book will provide a series of "stories" about how disruption of the environment and transmission from animal hosts is responsible for emerging human and animal diseases. American Society for Microbiology Press March 2014 HB: 978-1-5558-1842-5: £108.00 Monograph
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18 AMERICAN SOCIETY FOR MICROBIOLOGY PRESS
NEW EDITION Oral Microbiology and Immunology, 2nd Edition Edited by: Richard J. Lamont, University of Louisville, USA, George N. Hajishengallis, University of Pennsylvania, USA, and Howard F. Jenkinson, University of Bristol, UK
In the second edition of best-selling textbook Oral Microbiology and Immunology, an international panel of editors presents an in-depth, comprehensive understanding of the oral ecosystem and its role in human health and disease. Written specifically for dental students, dental practitioners, and healthcare professionals, Oral Microbiology and Immunology cohesively details the ecology, virulence, molecular biology, and immunogenicity of oral bacteria, viruses, and fungi and examines their interfaces with host cells and secretions. This new edition addresses the technological and conceptual advances that have increased our understanding of the etiology of oral diseases and the nature of pathogenic mechanisms and the host response, including: American Society for Microbiology Press • Genome sequencing of a bacterium or a community of November 2013 bacteria. PB: 978-1-5558-1673-5: £60.00 • Knockout mice deficient in specific components of both Textbook the innate and adaptive immune systems. • High-resolution and 3D imaging techniques of communities growing in biofilms and the intimate interactions between microbes and host cells.
Principles of Microbial Diversity James W. Brown, North Carolina State University, USA
PrinciPles of
Microbial Diversity
James W. BroWn
Principles of Microbial Diversity fills a currently empty niche in microbiology textbooks and provides a current and comprehensive view of microbial diversity. Divided into 3 sections, it begins with a practical guide to molecular phylogenetic analysis, focusing on how to create and interpret phylogenetic trees, and an overview or survey of “the Tree of Life”. Section 2 focuses on the major phylogenetic groups of Bacteria and Archaea, and Section 3 considers primary research literature. The book concludes with a discussion of various conceptual aspects of microbial complexity, from genomics and cell biology. The textbook includes a series of ‘Questions for Thought’ at the end of each chapter. American Society for Microbiology Press May 2014 HB: 978-1-5558-1442-7: £83.00 Textbook
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19
Cheese and Microbes Edited by Catherine W. Donnelly, University of Vermont, USA
A scientific overview of the association of microbes with cheese, through the lens of select cheese varieties that result due to surface mold ripening, internal mold ripening, rind washing, cave aging, or surface smear rind development. This book: • explains the transformation of milk to cheese and how sensory attributes of cheese are evaluated • provides an overview of cheese safety and regulations governing cheese making, both in the US and abroad, to ensure safety • explores how the tools of molecular biology provide new insights into the complexity of the microbial diversity of cheeses • examines the biodiversity of traditional cheeses as a result of traditional practices • overviews research on the stability of the microbial American Society for Microbiology Press consortium of select traditional cheese varieties. March 2014 HB: 978-1-5558-1586-8: £108.00 Monograph
NEW TEXTBOOK Medical Biotechnology, 2nd Edition Edited by Bernard R. Glick, University of Waterloo, Ontario, Canada; Cheryl L. Patten, University of New Brunswick, USA; and Terry L. Delovitch, Robarts Research Institute, University of Western Ontario, Canada
Medical Biotechnology includes salient features of selected diseases to illustrate the applications of many biotechniques and biochemical mechanisms. It is a textbook for a wide range of courses intended for pre-med and medical students, dental students, pharmacists, optometrists, nurses, nutritionists, genetic counselors, hospital administrators, and individuals who are stakeholders in the understanding and advancement of biotechnology and its impact on the practice of modern medicine.
American Society for Microbiology Press January 2014 HB: 978-1-5558-1705-3: £85.00 Textbook
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20 AMERICAN SOCIETY FOR MICROBIOLOGY PRESS
GENERAL INTEREST Forgotten People, Forgotten Diseases Peter J. Hotez, The George Washington University and Sabin Vaccine Institute, USA Provides an overview of the neglected tropical diseases (NTDs) and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. American Society for Microbiology Press May 2013: 275pp: PB 978-1-5558-1874-6: £29.00
Germ Theory
Medical Pioneers in Infectious Diseases Robert P. Gaynes, Emory University School of Medicine, USA From Hippocrates to Lillian Wald—the stories of scientists whose work changed the way we think about and treat infection.
Microbes and Evolution Roberto Kolter, Harvard Medical School, USA, and Stanley Maloy, San Diego State University, USA Explore the fundamental role of microbes in the natural history of our planet with 40 essays written by microbiologists with a passion for evolutionary biology, whose thinking and career paths in science were influenced by Darwin’s seminal work On the Origin of Species. American Society for Microbiology Press May 2012: 320pp: PB 978-1-5558-1540-0: £11.00
To Catch a Virus
John Booss, Yale University, USA, and Marilyn August, USA Expert storytellers weave together the science, technological advances, medical urgencies, and human stories that chronicle the development of the field of diagnostic virology.
American Society for Microbiology Press March 2013: 392pp: PB 978-1-5558-1507-3: £29.00 American Society for Microbiology Press August 2011: 342pp: PB 978-1-5558-1529-5: £22.00
The Power of Plagues
Twelve Diseases that Changed Our World
Irwin W. Sherman, USA
Irwin W. Sherman, USA
A fascinating examination of epidemic diseases within a historical context. Examines the interrelationship between plagues and culture and details the ways this shaped the traditions and institutions of Western civilization. American Society for Microbiology Press December 2005: 431pp: PB 978-1-5558-1356-7: £22.00
Covers the history of twelve important diseases and addresses public health responses and societal upheavals.
American Society for Microbiology Press August 2007: 219pp: PB 978-1-5558-1466-3: £22.00
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AMERICAN SOCIETY FOR MICROBIOLOGY PRESS
IN THE NEW UK STORE: • Molecular Biology of the Cell, Fifth Edition • Essential Cell Biology, Fourth Edition • Janeway's Immunobiology, Eighth Edition • The Immune System, Third Edition • The Biology of Cancer, Second Edition and many more... All of our textbooks are available as e-books on the VitalSource platform. VitalSource Bookshelf® is available on PC and MAC, and various mobile App stores. E-books can be purchased in their entirety or as individual chapters, and are available as six month rentals.
Vitalsource Bookshelf® e-book software provides three-way access to your books: download, online, and mobile. Notes and highlights automatically stay in sync no matter where you make them.
www.store.vitalsource.co.uk Browse & order online: www.garlandscience.com
22 IMMUNOLOGY Janeway’s Immunobiology, Eighth Edition Kenneth M. Murphy, Washington University School of Medicine, USA
Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. Garland Science 2011: 888pp: 599 illus Pb: 978-0-8153-4243-4: £52.00 CONTENTS: 1. Basic Concepts in Immunology 2. Innate Immunity: The First Lines of Defense 3. The Induced Responses of Innate Immunity 4. Antigen Recognition by B-cell and T-cell Receptors 5. The Generation of Lymphocytes Antigen Receptors 6. Antigen Presentation to T Lymphocytes 7. Signaling Through Immune System Receptors 8. The Development and Survival of Lymphocytes 9. T-cell Mediated Immunity 10. The Humoral Immune Response 11. Dynamics of Adaptive Immunity 12. The Mucosal Immune System 13. Failures of Host Defense Mechanisms 14. Allergy and Allergic Diseases 15. Autoimmunity and Transplantation 16. Evolution of the Immune System
Case Studies in Immunology, Sixth Edition A Clinical Companion
Raif Geha and Luigi Notarangelo, both at Harvard Medical School, USA
Case Studies in Immunology highlights major common disorders of immunity, including genetic disorders of the immune system, immune-complex diseases, immune-mediated hypersensitivity reactions, and autoimmune and alloimmune diseases. Garland Science 2011: 376pp: 200 illus Pb: 978-0-8153-4441-4: £38.00 CONTENTS: 1. X-linked Agammaglobulinemia 2. CD40 Ligand Deficiency 3. Activation-induced Cytidine Deaminase Deficiency 4. Common Variable Immunodeficiency 5. X-linked Severe Combined Deficiency 6. Adenosine Deaminase Deficiency 7. Omenn Syndrome 8. MHC Class II Deficiency 9. DiGeorge Syndrome 10. Acquired Immune Deficiency Syndrome (AIDS) 11. Graft- Versus-Host Disease 12. MHC Class I Deficiency 13. X-linked Lymphoproliferative Syndrome 14. Hemophagocytic Lymphohistocytosis 15. Chediak-Higashi Syndrome 16. Wiskott-Aldrich Syndrome 17. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy 18. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease 19. Autoimmune Lymphoproliferative Syndrome (ALPS) 20. Hyper IgE Syndrome 21. Ataxia Telangiectasia 22. Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome 23. X-linked Hypohydrotic Ectodermal Dysplasia and Immunodeficiency 24. Interferon-γ Receptor Deficiency 25. Severe Congenital Neutropenia 26. Chronic Granulomatous Disease 27. Leukocyte Adhesion Deficiency 28. Recurrent Herpes Simplex Encephalitis 29. Interleukin 1 Receptor-associated Kinase 4 Deficiency 30. Congenital Asplenia 31. Hereditary Angioedema 32. Factor I Deficiency 33. Deficiency of the C8 Complement Component 34. Hereditary Periodic Fever Syndromes 35. Systemic Onset Juvenile Idiopathic Arthritis 36. Rheumatoid Arthritis 37. Systemic Lupus Erythematosus 38. Mixed Essential Cryoglobulinemia 39. Crohn’s Disease 40. Multiple Sclerosis 41. Autoimmune Hemolytic Anemia 42. Myasthenia Gravis 43. Pemphigus Vulgaris 44. Celiac Disease 45. Acute Infectious Mononucleosis 46. Hemolytic Disease of the Newborn 47. Toxic Shock Syndrome 48. Lepromatous Leprosy 49. Acute Systemic Anaphylaxis 50. Allergic Asthma 51. Atopic Dermatitis 52. Drug-induced Serum Sickness 53. Contact Sensitivity to Poison Ivy
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IMMUNOLOGY 23
NEW EDITION
The Immune System, Fourth Edition Peter Parham, Stanford University, USA
The Immune System, Fourth Edition, emphasizes the human immune system and synthesizes immunological concepts into a coherent, up-to-date, and reader-friendly account of how the immune system works. Written for undergraduate, medical, veterinary, dental, and pharmacy students, it makes generous use of medical examples to illustrate immunological concepts. The Fourth Edition has been extensively revised and updated. Innate immunity has undergone major revision to reflect this expanding and fast-moving field, and is now divided between two chapters. Chapters 4-9 have been updated and material has been consolidated to eliminate repetition. Mucosal immunology has exploded as a field since the Third Edition was published, thus its coverage in Chapter 10 has been significantly expanded and updated. Immunological memory and the secondary immune response now comprise the first part of Chapter 11. “Bridging Innate and Adaptive Immunity” will also have its own chapter, and the clinical chapters will be revised and updated with new immunotherapies. The Fourth Edition will be accompanied by an updated and greatly expanded question bank. Garland Science December 2014: 552pp: 480 illus Pb: 978-0-8153-4466-7: £48.00 CONTENTS: 1. Elements of the Immune System and their Roles in Defense 2. Innate Immunity: The Immediate Reaction to Infection 3. Innate Immunity: The Induced Response to Infection 4. Antibody Structure and the Generation of B-Cell Diversity 5. Antigen Recognition by T Lymphocytes 6. The Development of B Lymphocytes 7. The Development of T Lymphocytes 8. T Cell-Mediated Immunity 9. Immunity Mediated by B Cells and Antibodies 10. Mucosal Immunity 11. Immunological Memory and Vaccination 12. Bridging Innate and Adaptive Immunity 13. Failures of the Body’s Defenses 14. Over-reactions of the Immune System 15. Disruption of Healthy Tissue by the Immune Response 16. Transplantation of Tissues and Organs 17. Cancer and Its Interactions with the Immune System
Immunology: An Illustrated Outline, Fifth Edition David Male, The Open University, UK
Immunology: An Illustrated Outline is both a review guide to the essential principles of immunology and a concise dictionary of immunological terms. It can be used as a review tool in preparation for course exams and medical licensing exams, or as a refresher when this content is encountered in related life science areas, such as microbiology and virology. The book also enables readers to look up specific terms in the index and locate the definitions, making it a powerful reference for interns, residents, and physicians in clinical practice. Garland Science July 2013: 146pp Pb: 978-0-8153-4501-5: £15.00
CONTENTS: 1. The Immune System 2. Immune Recognition 3. Immune Responses 4. Immunopathology 5. Immunological Techniques
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24 IMMUNOLOGY Case Studies in Allergic Disorders
Hans Oettgen and Raif Geha, both at Harvard Medical School, USA
Case Studies in Allergic Disorders describes the basic cellular and molecular mechanisms involved in the pathogenesis of commonly occurring allergic diseases and introduces the rationale for targeted intervention in these mechanisms in the treatment of allergy. Case Studies in Allergic Disorders is intended for medical students and undergraduate and graduate students in immunology as well as residents in internal medicine and pediatrics and fellows in allergy. Garland Science 2012: 176pp: 110 illus Pb: 978-0-8153-4436-0: £32.00 CONTENTS: 1. Acute Systemic Anaphylaxis 2. Allergic Asthma 3. Allergic Rhinitis 4. Allergic Diseases of the Eye 5. Atopic Dermatitis 6. Contact Dermatitis 7. Transfusion Reaction 8. Drug-induced Serum Sickness 9. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease (IPEX) 10. Hereditary Angioedema 11. Urticaria 12. Food Allergy 13. Eosinophilic Esophagitis 14. Allergic Bronchopulmonary Aspergillosis 15. Hypersensitivity Pneumonitis and Occupational Lung Disease 16. Venom Hypersensitivity 17. Hypereosinophilic Syndromes 18. Churg-Strauss Vasculitis 19. Aspirin Sensitivity and Nasal Polyposis 20. Mastocytosis
Principles of Mucosal Immunology Society for Mucosal Immunology. Edited by Phillip D. Smith, University of Alabama at Birmingham, USA, Thomas T. MacDonald, Barts and the London School of Medicine and Dentistry, UK, and Richard S. Blumberg, Harvard Medical School, USA.
Principles of Mucosal Immunology is for graduate students, postdoctoral fellows and investigators in immunology and microbiology, and medical and dental students. Thirty-two chapters contained in seven sections present the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier—the gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems. Garland Science 2012: 512pp: 220 illus Pb: 978-0-8153-4443-8: £49.00 CONTENTS: I. Development and Structure of Mucosal Tissue II. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis III. Microbial Commensalism IV. Genitourinary Tract V. Nose, Airways, Oral Cavity, and Eyes VI. Infectious Diseases of Mucosal Surfaces VII. Specific Immune-mediated Diseases of Mucosal Surfaces
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IMMUNOLOGY 25 Atlas of Immunology, Third Edition Julius M. Cruse and Robert E. Lewis, both at University of Mississippi Medical Center, USA
With more than 1,300 figures, line drawings, and photographs, Atlas of Immunology clearly demonstrates that a picture is worth a thousand words. Each entry in this third edition has been revised to reflect recent advances in scientific knowledge based on current research. A new chapter, Immunophenotyping of Hematopoietic Malignancies, has been added and the History of Immunology chapter has been expanded, detailing pivotal research developments. The contents of the book range from photographs of field pioneers to illustrations of molecular structures of recently characterized cytokines, major histocompatibility complex molecules, immunoglobins, and molecules of related interest. CRC Press April 2010: 958pp: 1,348 illus Hb: 978-1-4398-0268-7: £87.00 CONTENTS: History of Immunology • Molecules, Cells and Tissues of the Immune Response • Antigens and Immunogens • Major Histocompatibility Complex • Antigen Processing and Presentation • B Lymphocyte Development and Immunoglobulin Genes • Immunoglobulin Synthesis, Structure and Function • Antigen-Antibody Interactions • The Thymus and T Lymphocytes • Cytokines and Chemokines • The Complement System • Types I, II, III and IV Hypersensitivity • Immunoregulation and Immunologic Tolerance • Autoimmunity. Mucosal Immunity • Immunohematology • Immunological Diseases and Immunopathology • Immunodeficiencies: Congenital and Acquired • Acquired Immune Deficiency Syndrome (AIDS) • Immunosuppression • Transplantation Immunology • Tumor Immunology • Immunity Against Microorganisms • Vaccines and Immunization • Therapeutic Immunology • Comparative Immunology • Immunological Methods and Molecular Techniques • Diagnostic Immunology • Index
Illustrated Dictionary of Immunology, Third Edition Julius M. Cruse and Robert E. Lewis, both at University of Mississippi Medical Center, USA
From the beginning, immunologists have maintained a unique nomenclature that has often mystified and even baffled their colleagues in other fields, causing them to liken immunology to a black box. With more than 1,200 illustrations, the Illustrated Dictionary of Immunology, Third Edition provides immunologists and non immunologists a single-volume resource for the many terms encountered in contemporary immunological literature. Encyclopedic in scope and including more than 1,200 illustrations, the content ranges from photographs of historical figures to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, immunoglobulins, and molecules of related interest to immunologists. These descriptive illustrations provide a concise and thorough understanding of the subject.
CRC Press April 2009: 816pp: 1,748 illus Hb: 978-0-8493-7987-1: £80.00
CONTENTS: Chapters A-Z Appendix I Mouse CD Chart Appendix II Complement Pathways Appendix III Cytokines and Their Receptors Appendix IV Chemokines and Their Receptors Appendix V Human Leukocyte Differentiation Antigens
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26 STRUCTURAL BIOLOGY The Molecules of Life
Physical and Chemical Principles John Kuriyan, University of California, Berkeley, USA, Boyana Konforti, Cell Press, USA, and David Wemmer, University of California, Berkeley, USA
The Molecules of Life is a textbook that provides an integrated physical and biochemical foundation for undergraduate students majoring in biology of health sciences. The book integrates fundamental concepts in thermodynamics and kinetics with an introduction to biological mechanism at the level of molecular structure.
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Garland Science 2012: 1032pp: 900 illus Pb: 978-0-8153-4188-8: £53.00
CONTENTS: Part I. Biological Molecules 1. From Genes to RNA and Proteins 2. Nucleic Acid Structure 3. Glycans and Lipids 4. Protein Structure 5. Evolutionary Variation in Proteins Part II. Energy and Entropy 6. Energy and Intermolecular Forces 7. Entropy 8. Linking Energy and Entropy: The Boltzmann Distribution Part III. Free Energy 9. Free Energy 10. Chemical Potential and the Drive to Equilibrium 11. Voltages and Free Energy Part IV. Molecular Interactions 12. Molecular Recognition: The Thermodynamics of Binding 13. Specificity of Macromolecular Recognition 14. Allostery Part V. Kinetics and Catalysis 15. The Rates of Molecular Processes 16. Principles of Enzyme Catalysis 17. Diffusion and Transport Part VI. Assembly and Activity 18. Folding 19. Fidelity in DNA and Protein Synthesis
With its quantitative approach and step-bystep derivations of key equations, this book prepares students in biology and health sciences well for the increasingly quantitative approaches in biology.
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Quarterly Review of Biology
It [The Molecules of Life] certainly provides a fine reference book for those trying to keep up with the vast amount of new information becoming available in this important area of biological science. The Biologist
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Principles of Proteomics, Second Edition Richard Twyman, WriteScience, UK
Principles of Proteomics, Second Edition provides a concise and userfriendly introduction to the diverse technologies used for the large-scale analysis of proteins, as well as their applications, and their impact in areas such as drug discovery, agriculture, and the fight against disease. Proteomics is a fast-advancing field in which researchers seek to capture all the proteins in the cell and characterize them in ever more detail. Principles of Proteomics has been fully updated to reflect the most recent developments in the field without losing its focus on the underlying principles. With worked examples, case studies profiling both established and emerging technologies, and further reading lists for each chapter, Principles of Proteomics is an ideal introduction for students, researchers and those working in the industry. Garland Science September 2013: 260pp: 142 illus Pb: 978-0-8153-4472-8: £47.00
CONTENTS: 1. The Origin and Scope of Proteomics 2. Strategies for Protein Separation 3. Strategies for Protein Identification 4. Strategies for Protein Quantitation 5. The Analysis of Protein Sequences 6. Structural Proteomics 7. Interaction Proteomics 8. Protein Modification in Proteomics 9. Protein Microarrays 10. Applications of Proteomics
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STRUCTURAL BIOLOGY 27 How Proteins Work
Mike Williamson, University of Sheffield, UK
How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. It will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics and will also serve as a valuable resource for graduate students and researchers.
Garland Science 2011: 464pp: 537 illus Pb: 978-0-8153-4446-9: £51.00
“
...very good coverage of domain structure and the assembly of proteins from basic functional units, and an excellent discussions of the evolution of proteins... Choice
”
CONTENTS: 1. Protein Structure and Evolution 2. Protein Domains 3. Oligomers 4. Protein Interactions in Vivo 5. How Enzymes Work 6. Protein Flexibility and Dynamics 7. How Proteins Make Things Move 8. How Proteins Transmit Signals 9. Protein Complexes: Molecular Machines 10. Multi-Enzyme Complexes 11. Techniques for Studying Proteins
Introduction to Protein Structure, Second Edition
Carl Branden (deceased), and John Tooze, Cancer Research UK
Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. Garland Science 1999: 410pp Pb: 978-0-8153-2305-1: £53.00
“
The strength of the book lies in its beautiful art work and its logical dissection of the baffling complexities of protein structures…admirably concise, lucid and accurate presentations of difficult concepts… invaluable for students.
”
Nature
CONTENTS: PART 1 BASIC STRUCTURAL PRINCIPLES 1. The Building Blocks 2. Motifs of Protein Structure 3. Alpha-Domain Structures 4. Alpha/Beta Structures 5. Beta Structures 6. Folding and Flexibility 7. DNA Structures PART 2 STRUCTURE, FUNCTION AND ENGINEERING 8. DNA Recognition in Procaryotes by Helix-Turn-Helix Motifs 9. DNA Recognition by Eukaryotic Transcription Factors 10. Specific Transcription Factors Belong to a Few Families 11. An Example of Enzyme Catalysis: Serine Proteinases 12. Membrane Proteins 13. Signal Transduction 14. Fibrous Proteins 15. Recognition of Foreign Molecules by the Immune System 16. The Structure of Spherical Viruses 17. Prediction, Engineering, and Design of Protein Structures 18. Determination of Protein Structures
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28 STRUCTURAL BIOLOGY Biomolecular Crystallography
Principles, Practice, and Application to Structural Biology Bernhard Rupp, q.e.d. Life Science Discoveries, California, USA
Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Deftly illustrated in full-color, the text describes mathematical and physical concepts in accessible and accurate language. Garland Science 2009: 800pp: 448 illus Hb: 978-0-8153-4081-2: £71.00
“
This book will be an essential part of the library of any department that claims to make contributions to modern biology.
”
Tom Blundell, Journal of Applied Crystallography
CONTENTS: I: FROM SEQUENCE TO CRYSTALS 1. Introduction: Preparing Your Study 2. Protein Structure 3. Protein Crystallization 4. Proteins for Crystallography II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY 5. Crystal Geometry 6. Diffraction Basics 7. Statistics and Probability in Crystallography III: FROM CRYSTALS TO DATA 8. Instrumentation and Data Collection IV: DETERMINING YOUR STRUCTURE 9. Reconstruction of Electron Density and the Phase Problem 10. Experimental Phasing 11. Non-Crystallographic Symmetry and Molecular Replacement 12. Model Building and Refinement V: MAKING SENSE OF YOUR STRUCTURE 13. Structure Validation, Analysis, and Presentation
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BIOPHYSICS 29 Physical Biology of the Cell, Second Edition Rob Phillips, California Institute of Technology, USA, Jane Kondev, Brandeis University, USA, Julie Theriot, Stanford University, USA, and Hernan Garcia, Princeton University, USA
Physical Biology of the Cell takes key cell biology experiments through a quantitative treatment to demonstrate how models can help refine our understanding and prediction of biological phenomena. Updated for the latest developments and now in full color, the Second Edition includes two new chapters on photosynthesis and pattern formation. Garland Science 2012: 1,057pp: 742 illus Pb: 978-0-8153-4450-6: £55.00
Physical Biology of the Cell, Second Edition won Best Undergraduate Textbook at the Society of Biology 2013 Book Awards.
CONTENTS: Part I The Facts of Life 1. Why: Biology By the Numbers 2. What and Where: Construction Plans for Cells and Organisms 3. When: Stopwatches at Many Scales 4. Who: “Bless the Little Beasties” Part II Life at Rest 5. Mechanical and Chemical Equilibrium in the Living Cell 6. Entropy Rules! 7. Two-State Systems: From Ion Channels to Cooperative Binding 8. Random Walks and the Structure of Macromolecules 9. Electrostatics for Salty Solutions 10. Beam Theory: Architecture for Cells and Skeletons 11. Biological Membranes: Life in Two Dimensions Part III Life in Motion 12. The Mathematics of Water 13. A Statistical View of Biological Dynamics 14. Life in Crowded and Disordered Environments 15. Rate Equations and Dynamics in the Cell 16. Dynamics of Molecular Motors 17. Biological Electricity and the Hodgkin-Huxley Model 18. Light and Life Part IV The Meaning of Life 19. Organization of Biological Networks 20. Biological Patterns: Order in Space and Time 21. Sequences, Specificity, and Evolution 22. Whither Physical Biology?
Introduction to Cell Mechanics and Mechanobiology Christopher R. Jacobs and Hayden Huang, both at Columbia University, USA, and Ronald Y. Kwon, University of Washington, USA
Introduction to Cell Mechanics and Mechanobiology teaches advanced undergraduate students a quantitative understanding of the way cells detect, modify, and respond to the physical properties within the cell environment. Coverage includes the mechanics of single molecule polymers, polymer networks, two-dimensional membranes, whole-cell mechanics, and mechanobiology, as well as primer chapters on solid, fluid, and statistical mechanics. Garland Science 2012: 350pp: 250 illus Pb: 978-0-8153-4425-4: £47.00 CONTENTS: 1. Introduction to Cell Mechanics 2. Introduction to Cell Biology 3. Primer to Solid Mechanics 4. Primer to Fluid Mechanics 5. Primer to Statistical Mechanics 6. Experimental Techniques and Analyses 7. Biopolymers 8. Polymer Networks and the Cytoskeleton 9. Biomembranes 10. Mechanobiology 11. Cellular Mechanotransduction
“
This excellent [book]…meets a real existing need in contemporary bioengineering education, and it does it effectively and successfully.
”
Computer Methods in Biomechanics and Biomedical Engineering
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30 BIOPHYSICS Molecular Driving Forces, Second Edition
Statistical Thermodynamics in Biology, Chemistry, Physics, and Nanoscience Ken A. Dill, Stony Brook University, USA, and Sarina Bromberg, Pescadero, California, USA
Molecular Driving Forces, Second Edition is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. Garland Science 2011: 720pp: 690 illus Pb: 978-0-8153-4430-8: £57.00
“
Kenneth Dill and Sarina Bromberg were presented with the 2012 Emily M. Gray Award “for their impact on the education and professional formation of countless scientists by writing a textbook which is a landmark in molecular biophysics, Molecular Driving Forces."
”
Biophysical Society
CONTENTS: 1. Principles of Probability 2. Extremum Principles Predict Equilibria 3. Heat, Work & Energy 4. Math Tools: Multivariate Calculus 5. Entropy & the Boltzmann Law 6. Thermodynamic Driving Forces 7. The Logic of Thermodynamics 8. Laboratory Conditions & Free Energies 9. Maxwell’s Relations & Mixtures 10. The Boltzman Distribution Law 11. The Statistical Mechanics of Simple Gases & Solids 12. What Is Temperature? What Is Heat Capacity? 13. Chemical Equilibria 14. Equilibria Between Liquids, Solids, & Gases 15. Solutions & Mixtures 16. The Solvation & Transfer of Molecules Between Phases 17. Physical Kinetics: Diffusion, Permeation & Flow 18. Microscopic Dynamics 19. Chemical Kinetics & Transition States 20. Coulomb’s Law of Electrostatic Forces 21. The Electrostatic Potential 22. Electrochemical Equilibria 23. Salt Ions Shield Charged Objects in Solution 24. Intermolecular Interactions 25. Phase Transitions 26. Cooperativity: The Hexlix-Coil, Isling & Landau Models 27. Adsorption, Binding & Catalysis 28. Multisite & Cooperative Ligand Binding 29. Bio & Nano Machines 30. Water 31. Water as a Solvent 32. Polymer Solutions 33. Polymer Elasticity & Collapse 34. Polymers Resist Confinement & Deformation
Fields, Forces, and Flows in Biological Systems Alan J. Grodzinsky, Massachusetts Institute of Technology, USA
Fields, Forces, and Flows in Biological Systems describes the fundamental driving forces for mass transport, electric current, and fluid flow as they apply to the biology and biophysics of molecules, cells, tissues, and organs. Basic mathematical and engineering tools are presented in the context of biology and physiology.
Garland Science 2011: 308pp: 200 illus Hb: 978-0-8153-4212-0: £57.00 CONTENTS: 1. Chemical Transport in Electrolyte Media 2. Electric Fields and Flows in Electrolyte Media 3. Electrochemical Coupling and Transport 4. Electrical Interaction Forces: From Intramolecular to Macroscopic 5. Newtonian Fluid Mechanics 6. Electrokinetics: MEMs, NEMs, and Nano-porous Biological Tissues 7. Rheology of Hydrated Biological Tissues and Polymeric Biomaterials Appendix A Integral Theorems Appendix B Differential Operators in Various Coordinate Systems Appendix C Vector Identities Appendix D System of Units Appendix E Physical Constants
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COMPUTATIONAL BIOLOGY 31 A First Course in Systems Biology Eberhard Voit, Georgia Institute of Technology, USA
A First Course in Systems Biology is a textbook that introduces the new paradigm of systems biology to advanced undergraduate and graduate students. Its main focus is on the development of computational models and their applications to diverse biological systems. The goal of the book is to provide the reader with sufficient background and access to methods to execute standard systems biology tasks, understand the modern literature and launch into specialized projects that address biological questions with theoretical and computational means. Garland Science 2012: 496pp: 250 illus Pb: 978-0-8153-4467-4: £48.00 CONTENTS: 1. Biological Systems 2. Introduction to Mathematical Modeling 3. Static Network Models 4. The Mathematics of Biological Systems 5. Parameter Estimation 6. Gene Systems 7. Protein Systems 8. Metabolic Systems 9. Signaling Systems 10. Population Systems 11. Integrative Analysis of Genome, Protein, and Metabolite Data 12. Physiological Modeling: the Heart as Example 13. Systems Biology in Medicine and Drug Development 14. Design of Biological Systems 15. Emerging Topics in Systems Biology
Phylogenomics A Primer
Rob DeSalle and Jeffrey Rosenfeld, both at American Museum of Natural History, USA
Phylogenomics introduces undergraduate and graduate students to the field of phylogenomics, the discipline that integrates evolutionary biology and genomics. The book presents an overview of the interlinking aspects of molecular biology, systematics, and bioinformatics; describes phylogenomic techniques such as PCR, CLUSTAL, and neighbor joining; and provides guidelines for navigating relevant databases such as GenBank, BLAST, and EDGAR. Garland Science 2012: 352pp: 160 illus Pb: 978-0-8153-4211-3: £40.00 CONTENTS: 1. Why Phylogenomics Matters 2. The Biology of Linear Molecules: DNA and Proteins 3. Evolutionary Principles – Populations and Trees 4. Databases 5. Homology and Pairwise Alignment 6. Multiple Alignments and Constructing Phylogenomic Matrices 7. Genome Sequencing and Annotation 8. Tree Building 9. Robustness and Rate Heterogeneity in Phylogenomics 10. Bayesian Analysis 11. Incongruence 12. Adapting Population Genetics to Genomics 13. Detecting Natural Selection in Genomes 14. Refining the Approach to Natural Selection at the Molecular Level 15. Genome-Level Analysis of Population Genetics 16. Genome Content Analysis 17. A Phylogenomic Perspective of Biological Diversity: Tree of Life, DNA Barcoding and Metagenomics 18. Microarrays in Evolutionary Studies and Functional Phylogenomics
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32 COMPUTATIONAL BIOLOGY Practical Bioinformatics
Michael Agostino, Pfizer Bioinformatics and Merrimack College, USA
Practical Bioinformatics is specifically designed for biology majors and is written for courses that have a practical, hands-on element. It contains many exercises to complement the straightforward and practical topics and is focused on the analysis of DNA, RNA, and protein sequences. It is designed to be the student’s first text for learning how to perform bioinformatics sequence analysis. Garland Science 2012: 394pp: 240 illus Pb: 978-0-8153-4456-8: £26.00
“
This [Practical Bioinformatics] is an excellent introductory book for bioinformatics, yet it contains enough detail to help both a serious researcher as well as a beginner in the field.
”
Science Books & Films
CONTENTS: 1. Introduction to Bioinformatics and Sequence Analysis 2. Introduction to Internet Resources 3. Introduction to the BLAST suite and BLASTN 4. BLASTP 5. Messenger RNA, cDNA, BLASTX and TBLASTN 6. Advanced Topics in BLAST 7. “Laboratory” Bioinformatics Tools 8. Protein Analysis 9. Explorations in short nucleotide sequences 10. MicroRNA and Pathway Analysis 11. Multiple Sequence Alignments 12. Browsing the Genome
Understanding Bioinformatics Marketa Zvelebil, The Institute of Cancer Research, UK, and Jeremy O. Baum, Imperial College London, UK
Suitable for advanced undergraduates and postgraduates, Understanding Bioinformatics provides a definitive guide to this vibrant and evolving discipline. Garland Science 2007: 798pp: 414 illus Pb: 978-0-8153-4024-9: £49.00
“
...provides an outstanding introduction to the main bioinformatics problems and tools, wellbalanced between applications to biological problems and theory behind data processing methods…
”
Computer Methods and Programs in Bioinformatics
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CONTENTS: Part 1: Background Basics 1. The Nucleic Acid World 2. Protein Structure 3. Dealing with Databases Part 2: Sequence Alignments 4. Producing and Analyzing Sequence Alignments 5. Pairwise Sequence Alignment and Database Searching 6. Patterns, Profiles, and Multiple Alignments Part 3: Evolutionary Processes 7. Recovering Evolutionary History 8. Building Phylogenetic Trees Part 4: Genome Characteristics 9. Revealing Genome Features 10. Gene Detection and Genome Annotation Part 5: Secondary Structures 11. Obtaining Secondary Structure from Sequence 12. Predicting Secondary Structures Part 6: Tertiary Structures 13. Modeling Protein Structure 14. Analyzing Structure-Function Relationships Part 7: Cells and Organisms 15. Proteome and Gene Expression Analysis 16. Clustering Methods and Statistics 17. Systems Biology Appendices: Background Theory • Appendix A. Probability, Information, and Bayesian Analysis • Appendix B. Molecular Energy Functions • Appendix C. Function Optimization
CHEMISTRY 33 Introductory Nanoscience Physical and Chemical Concepts
Masaru Kuno, University of Notre Dame, USA
Designed for upper-level undergraduate and graduate students, Introductory Nanoscience asks key questions about the quantitative concepts that underlie this new field. Using solved examples, this textbook shows to what extent we may predict the behavior and functionality of nanomaterials by understanding how their properties change with scale.
Garland Science 2011: 420 pp: 250 illus Pb: 978-0-8153-4424-7: £44.00 CONTENTS: 1. Introduction 2. Structure 3. Length Scales 4. Types of Nanostructures 5. Absorption and Emission Basics 6. A Quantum Mechanics Review 7. Model Quantum Mechanics Problems 8. Additional Model Problems 9. Density of States 10. Bands 11. Time-Dependent Perturbation Theory 12. Interband Transitions 13. Synthesis 14. Characterization 15. Applications Appendix: Useful Constants
Introduction to Bioorganic Chemistry and Chemical Biology David Van Vranken and Gregory A. Weiss both at University of California, Irvine, USA
Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Garland Science 2012: 478pp: 603 illus Pb: 978-0-8153-4214-4: £50.00 CONTENTS: 1. Fundamentals of Chemical Biology 2. The Chemical Origins of Biology 3. DNA 4. RNA 5. Peptide and Protein Structure 6. Protein Function 7. Glycobiology 8. Polyketides & Terpenes 9. Chemical Control of Signal Transduction
“
This book provides important information on the organic chemistry of biooligomers and their interactions in the functioning of cells. Advanced undergraduate students, graduate students in chemistry and molecular biology, as well as medical students will find this book of value.
”
Doodys Review
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34 PLANT AND MARINE BIOLOGY Plant Biology Alison M. Smith, John Innes Centre, UK, George Coupland, Max Planck Institute, Germany, Liam Dolan, John Innes Centre, UK, Nicholas Harberd, University of Oxford, UK, Jonathan Jones, John Innes Centre, UK, Cathie Martin, John Innes Centre, UK, Robert Sablowski, John Innes Centre, UK, and Abigail Amey, Science Editor, London, UK
Plant Biology is a textbook written for upper-level undergraduate and graduate students. Plant Biology is a ‘where we are now’ account of plant science. It acknowledges the distinguished history of the subject, but its approach is strongly influenced by the radically new outlook that has emerged in the last twenty years. Many of the recent advances in Plant Biology the authors describe are useful in the understanding of modern biology as a whole. Garland Science 2009: 679pp: 657 illus Pb: 978-0-8153-4025-6: £48.00 CONTENTS: 1. Origins 2. Genomes 3. Cells 4. Metabolism 5. Development 6. Environmental Signals 7. Environmental Stress 8. Interactions with Other Organisms 9. Domestication & Agriculture
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“
...abundantly and lavishly illustrated with original colour line drawings, and photographs and micrographs from leading plant laboratories and practitioners from around the world...
”
Nigel Chaffey Bath Spa University
PLANT AND MARINE BIOLOGY 35 Plant Biochemistry Caroline Bowsher, University of Manchester, UK, Martin Steer, University College Dublin, Ireland, and Alyson Tobin, University of St. Andrews, UK
Plant Biochemistry presents each topic from the cellular level to the ecological and environmental levels, placing it in the context of the whole plant. Biochemical pathways are represented as route maps, showing how one reaction follows another. These maps emphasize the dynamism and flexibility of the plant in the face of environmental challenges. Garland Science 2008: 500pp: 332 illus Pb: 978-0-8153-4121-5: £50.00
CONTENTS: 1. Introduction to Plant Biochemistry 2. Approaches to Understanding Metabolic Pathways 3. Plant Cell Structure 4. Light Reactions of Photosynthesis 5. Photosynthetic Carbon Assimilation 6. Respiration 7. Synthesis and Mobilization of Storage and Structural Carbohydrates 8. Nitrogen and Sulfur Metabolism 9. Lipid Biosynthesis 10. Alkaloids 11. Phenolics 12. Terpenoids
“
It [Plant Biochemistry] offers a fascinating vision of the living plant cell...clearly a textbook to recommend without any hesitation to students and their teachers...
”
Michel Delseny Universite de Perpignan
Plant Cell Walls
From Chemistry to Biology Peter Albersheim and Alan Darvill, both at Complex Carbohydrate Research Center, University of Georgia, USA, Keith Roberts Emeritus, John Innes Centre, UK, Ron Sederoff, North Carolina State University, USA, and Andrew Staehelin Emeritus, University of Colorado, USA
Plant Cell Walls provides an in depth and diverse view of the microanatomy, biosynthesis and molecular physiology of these cellular structures, both in the life of the plant and in their use for bioproducts and biofuels. Plant Cell Walls is a textbook for upper-level undergraduates and graduate students, as well as a professional-level reference book.
Garland Science 2010: 430pp: 405 illus Hb: 978-0-8153-1996-2: £69.00 CONTENTS: 1. The Cell Wall and Plant Anatomy 2. The Structural Polysaccharides of the Cell Wall and How They Are Studied 3. Biochemistry of the Cell Wall Molecules 4. Membrane Systems Involved in Cell Wall Assembly 5. Biosynthesis of Cell Wall Polymers 6. Architectural Principles and Variations 7. The Cell Wall in Growth and Development 8. Cell Walls and the Interaction of Plants with Microbes 9. Plant Cell Walls: A Renewable Material Resource
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36
PLANT AND MARINE BIOLOGY
Marine Microbiology, Second Edition Ecology and Applications
Colin Munn, University of Plymouth, UK
Marine Microbiology brings together microbial biology and ecology to create an integrated approach that addresses environmental, human health, and economic concerns. The Second Edition takes into account many new discoveries in the field. It is ideally suited for upper-level undergraduate and graduate students, and researchers. Garland Science 2011: 320pp: 131 illus Pb: 978-0-8153-6517-4: £48.00
“
...it is about as perfect as any text could get...
”
Leigh Owens James Cook University
CONTENTS: 1. Microbes in the Marine Environment 2. Methods in Marine Microbiology 3. Metabolic Diversity and Ecophysiology 4. Marine Bacteria 5. Marine Archaea 6. Marine Eukaryotic Microbes 7. Marine Viruses 8. Ocean Processes - Marine Microbes and the Carbon Cycle 9. Nutrient Cycles - Nitrogen, Sulphur and Phosphorus 10. Symbiotic Associations 11. Microbial Diseases of Marine Organisms 12. Marine Microbes as Agents of Human Disease 13. Microbial Aspects of Marine Biofouling, Biodeterioration and Pollution 14. Marine Microbes and Biotechnology
Biology of Fishes, Third Edition Quentin Bone, Marine Biological Association of the UK, Plymouth, UK, and Richard Moore, Coastal Carolina University, USA
The Third Edition of Biology of Fishes is chiefly about fish as remarkably efficient machines for coping with the many problems that life in water entails, and looks at many such special cases. Fishes form the largest group of vertebrates, with around 20,000 known species, and they display a remarkable diversity of size, shape, internal structure and ecology to cope with environments ranging from transient puddles to the abyssal depths of the sea. Taylor & Francis 2008: 450pp: 280 illus Pb: 978-0-415-37562-7: £50.00
CONTENTS: 1. Diversity of Fishes 2. Fishes and their Habitats 3. Swimming 4. Buoyancy 5. Gas Exchange, Blood and the Circulatory System 6. Osmoregulation and Ion Balance 7. Food and Feeding 8. Reproduction and Life Histories 9. Endocrine Systems 10. Sensory Systems and Communication 11. Nervous System 12. Immune System 13. Behavior and Cognition 14. Fisheries and Aquaculture
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BIOS INSTANT NOTES 37
BIOS INSTANT NOTES
Paperback: ÂŁ21.00
Analytical Chemistry, First Edition
978-1-8599-6189-6
Animal Biology, First Edition
978-1-8599-6325-8
Biochemistry, Fourth Edition
978-0-4156-0845-9
Bioinformatics, Second Edition
978-0-4153-9494-9
Chemistry for Biologists, Third Edition
978-0-4156-8003-5
Developmental Biology, First Edition
978-1-8599-6153-7
Ecology, Second Edition
978-1-8599-6257-2
Genetics, Fourth Edition
978-0-4156-9314-1
Human Physiology, First Edition
978-0-4153-5546-9
Immunology, Third Edition
978-0-4156-0753-7
Inorganic Chemistry, Second Edition
978-1-8599-6289-3
Mathematics and Statistics for Life Scientists, First Edition
978-1-8599-6292-3
Medical Microbiology, First Edition
978-1-8599-6254-1
Medicinal Chemistry, First Edition
978-1-8599-6207-7
Microbiology, Fourth Edition
978-0-4156-0770-4
Molecular Biology, Fourth Edition
978-0-4156-8416-3
Neuroscience, Third Edition
978-0-4156-0769-8
Organic Chemistry, Second Edition
978-1-8599-6264-0
Physical Chemistry, First Edition
978-1-8599-6194-0
Plant Biology, Second Edition
978-0-4153-5643-5
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38 TITLE INDEX A First Course in Systems Biology. . . . . . 31 Atlas of Immunology . . . . . . . . . . . 25 Biology of Aging . . . . . . . . . . . . . 4 Biology of Cancer, The . . . . . . . . . . . . . . 4 Biology of Disease. . . . . . . . . . . . . . 13 Biology of Fishes. . . . . . . . . . . . . . . 36 Biomolecular Crystallography. . . . . . . . . . . . . . 28 Case Studies in Allergic Disorders . . . . 24 Case Studies in Immunology. . . . . . . . . . . 22 Case Studies in Infectious Disease . . . . . . . . 13 Cell Signaling . . . . . . . . . . . . . . . . . 5 Cellular Signal Processing. . . . . . . . . . . . 5 Epigenetics . . . . . . . . . . . . . . . . . . 7 Essential Cell Biology . . . . . . . . . . . . . 1 Fields, Forces, and Flows in Biological Systems . . . 30 Gene Control. . . . . . . . . . . . . . . . 8 Genetic and Genomic Medicine. . . . . . . . . . . . . . . . 7 Genome Duplication. . . . . . . . . . . . . . 9 Genome Stability . . . . . . . . . . . . . . . . . 8 Genomes 3. . . . . . . . . . . . . . . . . . 9 How Proteins Work . . . . . . . . . . . 27 Human Evolutionary Genetics. . . . . . . . . . 6 Human Molecular Genetics. . . . . . . . . . . . . . 6 Illustrated Dictionary of Immunology. . . . 25 Immune System, The . . . . . . . . . . . . . 23 Immunology: An Illustrated Outline. . . . . . . . . . . . . . . . . . 23 Introducing Genetics. . . . . . . . . . . . . . . . . . . . . . . . . . 10 Introductory Nanoscience. . . . . . . . . . . . . . 33 Introduction to Bioorganic Chemistry and Chemical Biology. . . . . . . . . . . .33 Introduction to Cell Mechanics and Mechanobiology . . . 29 Introduction To Genetics. . . . . . . . . . . . . . . . 10 Introduction to Protein Structure . . . . . . . . . . 27 Janeway’s Immunobiology . . . . . . . . . . 22
Statistical Genetics . . . . . . . . . . . . . 9 Understanding Bioinformatics . . . . . . . . 32 Viruses . . . . . . . . . . . . . . . . . . . 11
American Society for Microbiology Press Cases in Medical Microbiology. . . . . . . . . . . . . 21 Cheese and Microbes . . . . . . . . . . . . . . 19 Clinical Laboratory Management. . . . . . . . . . . . . . . . 17 Clinical Microbiology Procedures Handbook . . . . . . . . . . . . . 16 Color Atlas of Medical Bacteriology . . . . . . . . . . . 15 Food Microbiology: An Introduction . . . . . . . . . . . . . 16 Food Microbiology: Fundamentals and Frontiers. . . .. . . 15 Manual of Clinical Microbiology . . . . . . . . . . . . . . . . . 15 Medical Biotechnology . . . . . . . . . . . . . . . . 19 Medically Important Fungi . . . . . . . . . . . 16 Molecular Biotechnology . . . . . . . . 16 Molecular Genetics of Bacteria . . . . . . . . . . . . 15 One Health: People, Animals and the Environment . . . . 17 Oral Microbiology and Immunology . . . . . . . . . . . . . . . 18 Principles of Microbial Diversity . . . . . . . . . . . . . . . 18 Principles of Virology . . . . . . . . . . . . . . . . . . . . 15 Scientific Integrity. . . . . . . . . . . . . . . . . . . . 20 Twelve Diseases that Changed the World . . . . . 16 Urinary Tract Infections . . . . . . . . . . . . . . . . . . . 21
BIOS Instant Notes
Living in a Microbial World . . . . . . . . . . . . . . 12 Marine Microbiology . . . . . . . . . . . . . . 36 Microbiology. . . . . . . . . . . . . . . 11 Molecular Biology of the Cell . . . . . . . . . . . . 2, 3 Molecular Biology of the Cell - The Problems Book . . . 3 Molecular Driving Forces . . . . . . . . . . . . 30 Molecules of Life, The . . . . . . . . . . . 26 Phylogenomics . . . . . . . . . . . 31 Physical Biology of the Cell . . . . . . . . . . 29 Plant Biochemistry . . . . . . . . . . . . . . 35 Plant Biology . . . . . . . . . . . . . . . 34 Plant Cell Walls . . . . . . . . . . . . . . 35 Practical Bioinformatics . . . . . . . . . . . . . . 32 Principles of Mucosal Immunology . . . . . . . . . 24 Principles of Proteomics. . . . . . . . . . . . 26 Protozoa and Human Disease . . . . . . . . . . . 12
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Analytical Chemistry . . . . . . . . . . . . . Animal Biology . . . . . . . . . . . . . . Biochemistry. . . . . . . . . . . . . . . . Bioinformatics . . . . . . . . . . . . . Chemistry for Biologists . . . . . . . . . . . Developmental Biology . . . . . . . . . . . . . Ecology. . . . . . . . . . . . . . . Genetics. . . . . . . . . . . . . . . . . . Human Physiology . . . . . . . . . . . . . . Immunology . . . . . . . . . . . . . . . . Inorganic Chemistry . . . . . . . . . . . Mathematics and Statistics for Life Scientists . . Medical Microbiology . . . . . . . . . . . . Medicinal Chemistry . . . . . . . . . . Microbiology . . . . . . . . . . . . . . . Molecular Biology . . . . . . . . . . . . . . . Neuroscience . . . . . . . . . . . . . . . . . . . . Organic Chemistry . . . . . . . . . . . . . . . . . . . . Physical Chemistry . . . . . . . . . . . . . . . . . . . . Plant Biology . . . . . . . . . . . . . . . . . . .
37 37 37 37 37 37 37 37 37 37 37 37 37 37 37 37 37 37 37 37
AUTHOR INDEX 39 Agostino, Michael . . . . 32 Ahmed, Nessar . . . . 13 Albersheim, Peter . . . . . . 35 Alberts, Bruce . . . . . 1, 2, 3 Amey, Abigail . . . . . 34 Armstrong, Lyle . . . . . . . . 7 Atlas, Ronald M. . . . . . . . 17 Baum, Jeremy O. . . . . . 32 Bell, Stephen . . . . . . . 9 Blumberg, Richard S. . . . . . 24 Bone, Quentin . . . . . . 36 Bowsher, Caroline . . . 35 Branden, Carl . . . . . 27 Bray, Dennis . . . . . . . . 1 Bromberg, Sarina . . . . . 30 Brown, James W. . . . . . . . . 18 Brown, Terry A. . . . . . . 9, 10 Buchanan, Robert L. . . . . . .15 Champress, Wendy . . . . . . . 15 Chinnery, Patrick. . . . . . . . . . . 7 Cole, Michael . . . . . . . 13 Coupland, George . . . . . 34 Cruse, Julian M. . . . . . . . 25 Darvill, Alan . . . . . 35 Dawson, Maureen . . . . . 13 De La Maza, Luis M. . . . . . . 15 Delovitch, Terry L. . . . . . . . . 19 DePamphilis, Melvin . . . . . 9 DeSalle, Rob . . . . . . . 31 Dill, Ken A. . . . . . 30 Dolan, Liam . . . . . . 34 Donnelly, Catherine W. . . . . . . 19 Doyle, Michael P. . . . . . . . 15 Enquist, Lynn W. . . . . . . . .15 Ferreira, Manuel . . . . . . 9 Flint, S. Jane . . . . . . . 15 Garcia, Hernan . . . . . . 29 Garcia, Lynn S. . . . . . . . . .16, 17 Geha, Raif . . . . . . 22, 24 Glick, Bernard R. . . . . . . . . . .16, 19 Goodship, Judith. . . . . . . . . . 7 Grodzinsky, Alan J. . . . . 30 Haber, James E. . . . . . . . 8 Hajishengallis, George N. . . . . .18 Harberd, Nicholas . . . . . 34 Harper, David R. . . . . . . 11 Henkin, Tina M. . . . . . . . . .15 Hofkin, Bruce . . . . . 12 Hollox, Edward . . . . . . . 6 Holton, John . . . . 13
Hopkin, Karen . . . . . . . . 1 Huang, Hayden . . . . . 29 Hunt, Tim . . . . . . . 2 Hurles, Matthew . . . . . 6 Irving, Will . . . . . . 13 Jacobs, Christopher R. . . . 29 Jenkinson , Howard F. . . . . . . . 18 Jobling, Mark . . . . . 6 Johnson, Alexander . . . 1, 2, 3 Jones, Jonathan . . . . 34 Kivislid, Toomas . . . . . . . 6 Klingm端ller, Ursula . . . . . 5 Kniel, Kalmia E. . . . . . . . .16 Kondev, Jane . . . . . . 29 Konforti, Boyana . . . . 26 Kuno, Masaru . . . . . 33 Kuriyan, John . . . . 26 Kwon, Ronald Y . . . . 29 Lamont, Richard J. . . . . . . . 18 Larone, Davise H. . . . . . . . .16 Latchman, David . . . . 8 Lewis, Julian . . . . . 1, 2, 3 Lewis, Robert E. . . . . . . . . 25 Lim, Wendell . . . . . . . . . 5 Lydyard, Peter. . . . . . 13 MacDonald, Thomas T. . . . 24 Macrina, Francis L. . . . . . . . . 20 Male, David. . . . . . . . . . . . 23 Maloy, Stanley . . . . . . . . . 17 Matthews, Karl R. . . . . . 16 Marks, Friedrich . . . . . . 5 Martin, Cathie . . . . . . 34 Mayer, Bruce . . . . . . . . . 5 McDonald, Roger . . . . . . . 4 Medland, Sarah . . . . . . . 9 Montville, Thomas J. . . . . . . 16 Moore, Richard . . . . . . . 36 Morgan, David . . . . . . 2, 3 Moszyk-Strelkauskas, Danielle . . 11 M端ller-Decker, Karin . . . . . 5 Munn, Colin . . . . . . . 36 Murphy, Kenneth M. . . . 22 Neale, Benjamin . . . . . . . 9 Notarangelo, Luigi . . . . . . 22 Oettgen, Hans . . . . . . . 24 Parham, Peter . . . . . 23 Pasternak, Jack J. . . . . . . . 16 Patthen, Cherly L. . . . . . . . 16, 19 Pawson, Tony . . . . . . . . 5 Peters, Joseph E. . . . . . . . . . 15
Peterson, Ellena M. . . . . . . 15 Pezzlo , Marie T. . . . . . . . . . 15 Phillips, Rob . . . . . . . 29 Porakishvili, Nino. . . . . . 13 Posthuma, Danielle. . . . 9 Racaniello, Vincent R. . . . . . . . . . 15 Raff, Martin . . . . . . . . 1, 2, 3 Read, Andrew . . . . . . . 6 Roberts, Keith . . . . 1, 2, 3, 35 Rosenfeld, Jeffrey . . . . 31 Rupp, Bernhard. . . . . . 28 Sablowski, Robert . . . . . . 34 Sederoff, Ron . . . . . 35 Sherman, Irwin W. . . . . . .16 Shigel, Janet T. . . . . . . . 15 Skalka, Anne Marie . . . . . . . . . .15 Smith, Alison M . . . . . 34 Smith, Chris . . . . . 13 Smith, Phillip D. . . . . . 24 Snyder, Larry . . . . . . . . . 15 Staehelin, Andrew. . . . . 35 Steer, Martin . . . . . 35 Strachan, Tom . . . . . . . 6, 7 Strelkauskas, Anthony . . . . 11 Strelkauskas, Jennifer . . . 11 Tan, Grace L. . . . . . . . 15 Theriot, Julie . . . . . . . 29 Thomas, Allison . . . . . . . . 10 Tobin, Alyson . . . . . 35 Tooze, John . . . . . . . . 27 Twyman, Richard . . . . . . . 26 Tyler-Smith, Chris . . . . . 6 van Vranken, David . . . . 33 Venkatesan, Pradhib . . . 13 Voit, Eberhard . . . . . . . 31 Walter, Peter . . . . . . 1, 2, 3 Ward, Kate . . . . . . . 13 Weinberg, Robert A. . . . 4 Weiss, Gregory A . . . . 33 Wemmer, David . . . . .26 Williamson, Mike . . . . . 27 Wilson, John . . . . . . . 2 Wiser, Mark F. . . . . . . . . 12 Wood, Ed . . . . . . . . . . 13 Zvelebil, Marketa . . . . . 32
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