Human Evolutionary Genetics

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3 Park Square, Milton Park Abingdon, Oxfordshire OX14 4RN UK

—HUMAN GENETICS

“I strongly recommend Human Evolutionary Genetics as an undergraduate textbook. At the same time, I recommend this book to any readers with an interest in human evolution or human genetics.”

—AMERICAN JOURNAL OF HUMAN GENETICS

“This is an absolutely superb book! I have been recommending it enthusiastically to professional colleagues, graduate students, and even the occasional highly motivated undergraduate student, and the response has been overwhelmingly positive. Not only is the book unique in terms of topical coverage, but it is also extremely well executed. In fact, it is one of the best textbooks on any subject I have ever read. It belongs on the shelves of everyone interested in the genetic aspects of human evolution.”

—HUMAN GENOMICS

“I strongly recommend this book to anyone with an interest in human evolutionary genetics or anthropological genetics. It would be an ideal choice for advanced undergraduates and graduate courses on this topic, and would also be a key reference for those active in such research.”

Praise for the First Edition of HUMAN EVOLUTIONARY GENETICS:

NEW SECOND EDITION

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HUMAN EVOLUTIONARY GENETICS Second Edition

Frequency of lactase persistence phenotype

Mark Jobling, University of Leicester, UK, Edward Hollox, University of Leicester, UK, Matthew Hurles, Wellcome Trust Sanger Institute, Hinxton, UK, Toomas Kivisild, University of Cambridge, UK, and Chris Tyler-Smith, Wellcome Trust Sanger Institute, Hinxton, UK

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Now in full-color, the Second Edition of HUMAN EVOLUTIONARY GENETICS has been completely revised to cover the rapid advances in the field since publication of the highly regarded First Edition. Written for upper-level undergraduate and graduate students, it is the only textbook to integrate genetic, archaeological, and linguistic perspectives on human evolution, and to offer a genomic perspective, reflecting the shift from studies of specific regions of the genome towards comprehensive genomewide analyses of human genetic diversity.

HUMAN EVOLUTIONARY GENETICS is suitable for courses in Genetics, Evolution, and Anthropology. Those readers with a background in anthropology will find that the streamlined genetic analysis material contained in the Second Edition is more accessible. The new edition also integrates new technologies (including next-generation sequencing and genomewide SNP typing) and new data analysis methods, including recent data on ancient genomes and their impact on our understanding of human evolution. The book also examines the subject of personal genomics and its implications.

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Section III: Where and When Did Humans Originate?

Section V: How Is An Evolutionary Perspective Helpful?

Section I: How Do We Study Genetic Variation?

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15. Understanding the Past, Present and Future of Phenotypic Variation 16. Evolutionary Insights into Simple Genetic Diseases 17. Evolution and Complex Diseases 18. Identity and Identification

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An Introduction to Human Evolutionary Genetics

Organization and Inheritance of the Human Genome Human Genome Variation Finding and Assaying Genome Diversity

Section II: How Do We Interpret Genetic Variation?

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Processes Shaping Diversity Making Inferences from Diversity

Humans as Apes What Genetic Changes Have Made Us Human?

Origins of Modern Humans

Section IV: How Did Humans Colonize the World?

10. The Distribution of Diversity 11. The Colonization of the Old World and Australia 12. Agricultural Expansions 13. Into New Found Lands 14. What Happens When Populations Meet?

July 2013 • 650 pages • 357 illustrations

A sample chapter and detailed table of contents are available at www.garlandscience.com/heg2.

Please also visit the website to order an examination copy of the book for consideration on your course.

Paperback • 978-0-8153-4148-2 • £49.00

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Figure 15.11: Frequency of lactase-persistence alleles in different populations.

NEW TO THE SECOND EDITION •

Two new authors contributing additional expertise in genome variation, infectious disease, primatology and anthropology.

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Now with a new layout and in full-color throughout, making the text and figures easier to read.

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Two additional chapters, reflecting developments in understanding the human genome in the context of other hominid and great ape genomes, and in complex disease.

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The guest-authored ‘Opinion Boxes’ are retained, with completely new boxes and new guest authors to reflect current issues and controversies.

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Each chapter ends with in-depth questions that are suitable for use as homework assignments or exam questions.

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Comprehensive glossary of over 1,300 terms, doubling the terms in the first edition.

CONTENTS 1.

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INSTRUCTOR RESOURCES •

Figures in Powerpoint® and JPEG formats.

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