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Blood sampling method Less expensive and no painful procedures Patent pending with 3 biomarkers and an algorithm to generate results in 4 different stages Validated with 500+ samples

Hepatitis B Hepatitis C Alcoholic Liver Disease Metabolic / Non-Alcoholic Fatty Liver Disease

BioFibroScore ® platform shows an excellent accuracy (>0.95) in all stages, especially in early stages. The technology has been offered as a service bundling as Liver20 TM.

AUROC BioFibroScore ®

FIBROSIS STAGES F≥1

F≥2

F≥3

F≥4

>0.95

>0.95

>0.95

>0.95

ELISA Kits & Instruments, RT-PCR & instruments, Raw Materials, Labware, & CLIA (new) A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw

T +886 3 577 9221

F +886 3 577 9227

www.gbc.com.tw



Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB WatoTM

An Automatic ELISA Plate Washer

FOCUSING ON YOUR NEEDS Various types of plate can be supported and are easily inter-changeable in the plate carrier to maximize the washing performance. GB WatoTM is an automatic ELISA Strip / Plate Washer with built-in incubator & programmable timer.

PRODUCT HIGHLIGHTS Specifically designed Manifold assembly to prevent any scratching on bottom of well Programmable soak time, wash cycles and dispensing volume Onboard two-plate incubator at 37 with programmable timer Waste bottle full warning with audible alarm Built-in stabilizer Continuous aspiration to prevent overflow Removable manifold Ability to wash single strip of 8 wells


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care. GB WATO TM TECHNICAL SPECIFICATION Manifold

8 Way Manifold Dispensing

Dispensing

Method : Specially designed Peristaltic Pump Volume : 300 to 400 µL in steps of 50 µL

Aspirating

Method : Continuous through diaphragm pump while Dispensing hence preventing overflow Residual Volume : < 5 µL

Waste Bottle

One (Capacity 2 liters) with audible alarm when bottle is completely filled in with waste solution

Wash Bottle

One (Capacity 2 liters)

Rinse Bottle

One (Capacity 2 liters)

Display

Single line Backlit LCD with 16 characters

Liquid contact materials

Silicon, Stainless steel, derline

Memory

8 KB Non volatile RAM battery back up suppor ting 35 open channels

Washing Method

Longwash, Shortwash Rinsing, Priming

Incubator

For Two ELISA Plates, 37º C

Timer

Individually Programmable

Power

Wattage : 50 Watts Voltage : 115 - 230 Volts ± 10%, 50 /60 Hz.

Operating Position

On horizontal, rigid, flat and vibration free surface

Operating Conditions

Temperature : + 18º C to 35º C Humidity : up to 85 %

Storage Conditions

Temperature : - 10º C to 60º C Humidity : up to 85 %

Enclosure

ABS Fire retardant

Size (cm)

35 X 35 X 13 (lxwxh)

Weight

6 Kgs

ORDERING INFORMATION Catalog No. S00346

Description GB WatoTM

Package 1 unit 2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB TempCardTM

Temperature Recorder

MADE SPECIALLY FOR YOU GB TempCardTM Temperature Recorder incorporates an innovative temperature sensor built inside this portable device. GB TempCardTM has been designed to endure hard damages yet still provide a fast reaction time.

PRODUCT HIGHLIGHTS Alert indicator – indicates if readings are outside of preset limits OK indicator indicates if still recording and if readings within configured limits Credit card sized case – thin enough to be easily mailed “letter rate”. Real time clock records time & temperature simultaneously Highly reliable and accurate Pre-Start Logging - Configurable to record even when "start" button has not been pressed High performance at lower cost Credit Card sized design - easy to carry and transport Re-calibration function available

USER-FRIENDLY INTERFACE GB TempCardTM comes with a great user-friendly interface software, TempCardTM Analyzer, for reading and analyzing collected data. GB TempCardTM Analyzer provides functions including delayed start, sampling interval, number of readings, continuous or fixed number of readings and ALERT function setup. Data recorded can be downloaded or exported in excel.


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB TEMPCARD TM TECHNICAL SPECIFICATION Capacity

8000 temperature readings (16Kbytes memory)

Frequency

Adjustable, 30 seconds to several hours

Download Time

Typically with full memory in less than 5 seconds depending on computer or readout device used

Environmental

IP65

Battery

3V Lithium

Life

2~3 years on regular uses

Real Time Clock

Installed with Real Time Clock. Rated accuracy ±25ppm @ 25°C (equiv to 2.5 seconds/day) Rated temperature coefficient is -0.034±0.006ppm/°C (i.e typically +/- 0.00294seconds/day/°C)

Dimension

86mm (L) x 55mm (W) x 8.6mm (H)

Weight

35g

Case Material

Polycarbonate

EMC Compliance

Tested and complies with EC EMC directives (EN 50081-1:1992 & EN 61000-6-1:2001)

EN12380 Compliance

Tested and complies to EN12830:1999 for transport, storage and distribution of chilled, frozen, deep frozen, quick-frozen food and others

ORDERING INFORMATION Catalog No. S00351

Description GB TempCardTM

Package 1 unit 2013/Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB RitoTM

An Automatic ELISA Plate Reader

FOCUSING ON YOUR NEEDS GB RitoTM is an automatic ELISA Plate Reader with user-friendly touch interface and software. GB RitoTM can be used for all routine immunoassays, biochemicals, hormones, and drug levels. It is an economical reliable and high precision instrument.

PRODUCT HIGHLIGHTS Robust system with built-in stabilizer Built-in shaker with variable speed & duration Results printing in matrix mode format Option to run multiple blank in cut-off mode Bichromatic readings Ability to read from any strip in a single plate Extensive curve plotting


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care. GB RITO TM TECHNICAL SPECIFICATION Interface

TOUCH PANEL / KEYPAD

Linear measurement range

0.000 to 3.000 Absorbance Units(A)

Photometirc Accuracy

± 2% or 0.005 whichever is higher, from 0 to 1.5 A ± 3% from 1.5 A to 3.0 A

Drift

<0.005 A/hr

Photometric Linearity

2.5 A

Optical measurement

8 Channel

Filters

Type of Filter Wave Length Half Bandwidth Selection

Light Source

Tungsten halogen lamp

Warm up time

90 seconds (built - in)

Display

6” Graphics LCD, Negative Blue, STN

Curve Plotting

Graphical Representation on Printer

Plate Carrier Movement

Precisely through the stepper motor

Printer

Built in Thermal Printer 52 columns

Memory

64 KB Non Volatile RAM Battery backup suppor ting125 open channels

Analysis Mode

Absorbance Cut - off Multi - Standard % Absorbance

RS232 Serial Port

2400 baud, 8 data, 1 stop, no parity bits / USB

Power

Wattage : 50 Watts Voltage : 115 - 230 Volts ± 10%, 50 / 60 Hz.

Operating Position

On horizontal flat, rigid and vibration free surface

Operating Conditions

Temperature : From + 18º C to 35º C Relative Humidity : up to 80 %

Storage Conditions

Temperature : From - 10º C to 35º C Relative Humidity : up to 80 %

Enclosure

ABS Fire Retardant

Size (cm)

36 X 36 X 22 (lxwxh)

Weight

10 Kgs

: Narrow band Interference : 405nm, 450nm, 492nm, 560nm, 630nm : 10 nm ± 2nm : Automatic by Stepper Motor

ORDERING INFORMATION Catalog No. S00345

Description GB RitoTM

Package 1 unit 2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB HBV RealQuant™ PCR Kit

In-Vitro Quantification of Hepatitis B Virus DNA

FEATURES GB HBV RealQuant™ PCR is an in vitro real time polymerase chain reaction (PCR) kit for the quantitation of Hepatitis B Virus (HBV) DNA in human plasma or serum from HBV-infected individuals.

PERFORMANCE COMPARISON Correlation

Accuracy

GB HBV RealQuant™ PCR kit shows

Base on Clinical and Laboratory Standards

great result comparing with its compara-

Institute (CLSI) documents, the CV should

tor. Both GB HBV RealQuant™ PCR Kit

be less than 35%, and both Comparator

and its comparator show equivalency

HBV Test and GB HBV RealQuant™ PCR

(between

37~107

were passed. Both Comparator HBV Test

IU/mL).

and GB HBV RealQuant™ PCR were shown to be linear in serum across the range of WHO HBV DNA concentrations.

6 GBC

Correlation

log IU/mL

6

Target WHO Conc.

8

R2=0.966

4

2

Accuracy

log IU/mL

5

R2=0.955

4 3

R2=0.955

2 1 0

0 0

2

4

6

8

Comparator

10 log IU/mL

0

1

2

3

4

5

Target HBV Conc.

6 log IU/mL Comparator GB

Comparator

GB HBV RealQuant™ PCR

CT value & Conc.

CT value & Conc.

L1

N/A (>1.1x108 IU/mL)

9.52/3.31x109 IU/mL

L2

N/A (>1.1x108 IU/mL)

8.54/3.47x108 IU/mL

L3

7.58/3.80x107 IU/mL

7.63/4.27x107 IU/mL

Sample ID


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB HBV REALQUANT™ PCR SPECIFICATION Certificates

TFDA / CE

Linear Range

10 IU~2.0E+09 IU/mL for 0.5mL input

LOD

9.8 IU/mL for 0.5mL input, 53 IU/mL for 0.2 mL input

Precision (CV%)

2.00 (log10IU/mL)=13.87%: 4.30 (log10IU/mL)=3.12%; 6.30 (log10IU/mL)=1.41%

Genotype Detection

A, B, C, D, E, F, G, wild types and mutants

Specimen Type

Serum and plasma

Time to Result

All processes including extraction within 3~4 hours (Manual or Automation)

Configuration

Master Mix, Primer, Probe, Internal Control, 5 Quantification Standard

Standardization

WHO International Standard for HBV DNA(97/746)

GB ANALYZER ECOSYSTEM GB GenesisTM e1000 DNA/RNA Extraction System GB GenesisTM s1000 DNA/RNA Extraction System GB GenesisTM s2000 DNA/RNA Extraction System QIAGEN Rotor-Gene Q - 2 channels RealTime PCR Cycler QIAGEN Rotor-Gene Q - 5 channels RealTime PCR Cycler

ORDERING INFORMATION Catalog No. 4HBPA2 S00340 S00341 S00352 S00343 S00353

Description GB HBV RealQuant™ PCR Kit GB Genesis™ e1000 GB Genesis™ s1000 GB Genesis™ s2000 QIAGEN Rotor-Gene Q - 2 channels QIAGEN Rotor-Gene Q - 5 channels

Package 48 tests/kit 1 unit 1 unit 1 unit 1 unit 1 unit 2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB HBsAg ELISA Kit (SURASE B-96) Detecting Hepatitis B Surface Antigen FEATURES Certificates: CE marked and TFDA Fulfilled new CTS of the European IVD Directive (2009 / 108 / EC) Detecting all Pre Core Mutant Panel A Hepatitis B Pre Core Mutant Panel from Teragenix, USA was used to test and validate. Studies showed GB HBsAg (SURASE96) can detect the results while panel's dilution ratio is 1:2 or 1:5.

39Y

/C

14

8T

G14

5K

Higher Sensitivity in Mutant Sample Detection

7T

4D

6 E1

C1 4

C1

5R 14

E

L

P142

41

L/G

42

P1

K1

D144G

Higher Sensitivity in Mutant Sample Detection

4N

S17

C137W

113A114

Y134S

P12

0L

31P

22

R 24 C1

T

2I

T123N

E12

22

R1

13

T

R1

1I

122R A123

T1

I

GB HBsAg ELISA Kit (SURASE B-96) SURASE B-96 17 / 21 Reference kit

14 / 21


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB HBsAg SURASE B-96 SPECIFICATION Diagnostic Sensitivity

100% (European Performance Evaluation)

Diagnostic Specificity

99.58% (European Performance Evaluation)

Intra-assay reproducibilty

The calculated CV's range between 3.7% and 11.36%

Time Saving

Without sample dilution & short substrate incubation time

Substrate

TMB

Certification

TFDA/CE

Method

direct sandwich method

Sample Type

serum / plasma

Sample Volume

100 ÂľL

Shelf Life

18 months

GB ANALYZER ECOSYSTEM GB KiwiTM e2000 ELISA Automatic System GB KiwiTM e4000 ELISA Automatic System GB KiwiTM eGility ELISA Automatic System

ORDERING INFORMATION Catalog No. 4SGE3 4SGE11 S00337 S00338 S00339

Description GB HBsAg (SURASE B-96) GB HBsAg (SURASE B-480) GB KiwiTM e2000 ELISA Automatic System GB KiwiTM e4000 ELISA Automatic System GB KiwiTM eGility ELISA Automatic System

Package 96 tests/kit 480 tests/kit 1 unit 1 unit 1 unit 2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GBTronic

Automatic Electronic Pipette

FOCUSING ON YOUR NEEDS The GBTronic is one of the easiest electronic pipettes to set and use. You can choose between the most widely used pipetting modes including reverse pipetting, multi dispensing, mixing and squential dispensing, or store up to 9 of your own protocols.

PRODUCT HIGHLIGHTS Consistent accuracy and precision can be easily achieved User’s operation interface is as easy and graphical as your cellular phone Light-weight and ergonomic design prevent Repetitive Stress Injury (RSI) Multiple protocols make your tedious lab job a breeze 9 memory settings for storing your protocols Lithium battery guarantees no leakage and more hours of operation 5 speed settings for different viscous samples Affordable prices Complies with ISO-8655, CE and GLP


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

ORDERING INFORMATION Single Catalog No. S00382 S00383 S00384 S00385

Description 1-channel A-pette electronic pipette, 0.5-10 ul 1-channel A-pette electronic pipette, 2-20 ul 1-channel A-pette electronic pipette, 10-200 ul 1-channel A-pette electronic pipette, 100-1,000 ul

Inaccuracy % / Imprecision % / Color 4-1 2.5-0.4 4-1 2.5-0.4 2.5-0.6 1-0.15 2.5-0.6 0.6-0.15

Description 8-channel A-pette electronic pipette, 0.5-10 ul 8-channel A-pette electronic pipette, 2-20 ul 8-channel A-pette electronic pipette, 10-200 ul 8-channel A-pette electronic pipette, 100-1,200 ul

Inaccuracy % / Imprecision % / Color 4-1.5 2.5-0.5 4-1 2.5-0.5 3-0.6 1-0.15 3-0.5 0.8-0.2

Multi Catalog No. S00386 S00387 S00388 S00389

2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB Fit X1TM

Automatic Pipetting System

FOCUSING ON YOUR NEEDS GB Fit X1TM is an automated, high-precision pipetting system specifically designed for low-volume PCR/qPCR sample preparation. Fit X1TM is designed to replace the manual process of PCR/qPCR sample preparation. Precision and consistency are the key feature to make sure reagents are dispensed accurately. Fit X1TM offers simplicity and functionality for you to produce the best results!


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care. GB FIT X1 TM TECHNICAL SPECIFICATION

Worktable Capacity

2 or 3 x 96 / 384 SBS PCR plates 2 or 1 x 96 tip rack (50/200 ul) Reagent Area 1: 8 x 1.5/2 ml microcentrifuge tube Reagent Area 2: 6 x 2 ml storage tube (free standing) and 1 x 5 ml bottle

Function

Liquid (Sample/Reagent) Transfer (LT) Multiple Dispense (MD) Serial Dilution (SD) Hold (Pause) Mixing (MIX) Loop

Automated Pipetting Module

Interchageable 1/8-channel, Maximum volume 50 ul/200 ul

Connection

RS-232, USB 1.0

Power Supply

100~240V, 50/60 Hz, 100W

Size (W x D x H)

590 x 440 x 460 mm

Weight

25 Kg

ORDERING INFORMATION Catalog No.

Description

X1TM

Fit S00390

4-plate Automated Pipetting System with 1 x APM, 1 x PC and SoFitTM software.

Interchangeable Automated Pipetting Module S00391 1-channel, 50 ul Pipetting Module S00392 8-channel, 50 ul Pipetting Module S00393 1-channel, 200 ul Pipetting Module S00394 8-channel, 200 ul Pipetting Module Robotic Tips S00395 S00396 S00397 S00398

FitTipTM 50 ul, non-sterile, 96 tips/rack; 10 racks/pack FitTipTM 200 ul, non-sterile, 96 tips/rack; 10 racks/pack FitTipTM 50 ul, sterile, 96 tips/rack; 10 racks/pack FitTipTM 200 ul, sterile, 96 tips/rack; 10 racks/pack

Accessories S00399 S00400 S00401 S00402 S00403 S00404 S00405 S00406 S00407

96 tips rack adapter Leviated 96-well PCR plate adapter Leviated 384-well PCR plate adapter 4 x 2 1.5ml tubes adapter 3 x 2 2ml storage tubes & 1 x 5 bottle adapter FitTipTM 96 adapter for 96-well PCR plates FitTipTM 384 adapter for 384-well PCR plates FitTipTM R10 adapter for 4 x 2 1.5ml tubes FitTipTM R20 adapter for 3 x 2 2ml storage tubes and 1 x 5ml bottle 2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB anti-HCV V4.0 ELISA Kit (NANBASE C-96 V4.0)

EIA Kit for Direct Detection of HCV Antibody FEATURES Certificates: CE marked and TFDA

New Method: double antigen direct sandwich principle Time Saving: without sample dilution and short substrate incubation time

4~7 Days Earlier Detection

HCV Reagent Kit - Brand A

21.6 days

HCV Reagent Kit - Brand B

22.8 days

HCV Reagent Kit - Brand C GB anti-HCV V4.0 (NANBASE C-96 V4.0)

HCV Reagent Kit - Brand D

17.7 days

0

22.9 days

24.9 days

4

8

12

16

20

days

24

HCV Reagent Kit - Brand E HCV Reagent Kit - Brand F

23.5 days 23.0 days

10X More Sensitive

Anti-HCVlgG(S/Co)

30

GB anti-HCV V4.0 (NANBASE C-96 V4.0)

25 20 15 10

CE Marked Reference Kit

5

Cut off

0 0

5

10 15 Serial Dilution Steps

20

PEI Reference Material High Positive Sample 1 High Positive Sample 2 Cut off


Industry-Leading In-Vitro Diagnostic Device Manufactuer

Your Liver. We Care.

GB anti-HCV V4.0 (NANBASE C-96 V4.0) SPECIFICATION Diagnostic Sensitivity

100.00%

Diagnostic Specificity

99.80%

Intra-assay reproducibilty

The calculated CV's range between 4.7% and 8.51%

Time Saving

Without sample dilution & short substrate incubation time

Substrate

TMB

Certification

TFDA/CE

New Method

double antigen direct sandwich principle

Sample Type

serum / plasma

Sample Volume

100 ÂľL

Shelf Life

18 months

GB ANALYZER ECOSYSTEM GB KiwiTM e2000 ELISA Automatic System GB KiwiTM e4000 ELISA Automatic System GB KiwiTM eGility ELISA Automatic System

ORDERING INFORMATION Catalog No. 4NAE3 4NAE12 S00337 S00338 S00339

Description GB anti-HCV V4.0 (NANBASE C-96 V4.0) GB anti-HCV V4.0 (NANBASE C-480 V4.0) GB KiwiTM e2000 ELISA Automatic System GB KiwiTM e4000 ELISA Automatic System GB KiwiTM eGility ELISA Automatic System

Package 96 tests/kit 480 tests/kit 1 unit 1 unit 1 unit

2013.Mar.

A No.6, Innovation First Road, Hsinchu Science Park, Taiwan, R.O.C. E sales.group@gbc.com.tw T +886 3 577 9221

www.gbc.com.tw

F +886 3 577 9227


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