pirogovka2010B

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������ «���������» Pediatrics INFECTIOUS COMPLICATIONS AFTER RENAL TRANSPLANTATION IN CHILDREN R.I. Checiches, V.V. Obada University of Medicine and Pharmacy «Iuliu Hatieganu» Cluj Napoca, Romania Department of Pediatrics The department s chairperson Prof. MD M. Andreica The project s advisor Assoc. Prof. MD A. Bizo

IMPROVEMENT OF THE MEASURES TO REHABILITATION OF CHILDREN WITH PATHOLOGY IS AN INTERVIEWED MOTOR DEVICE Z.N. Ismailov, F.N. Samadov, G.A. Fayziyeva Tashkent Pediatric Medical Institute Department of Child Neurology The department s chairperson Prof. G.K.Sadikova The project advisor Prof. G.K.Sadikova

The aim of our study was a retrospective evaluation of the prevalence,epidemiology and clinical features of the infectious complications after renal transplantation in children.Renal transplantation is the preffered treatment modality for children with end-stage renal disease. Allograft nephropaty remains in some cases an unsolved challenge and specific risk factors such as infectious complications seem to be a serious problem. A retrospective analysis was performed and the episodes of infectious complications were recorded for all patients at our renal transplantation center. We also hypothesized that specific risk factors,such as demographic features,underlying diagnoses and surgery before transplantation would increase the risk of infectious complications. 100 children and adolescents aged between 2.6 and 18 years (1995 2009) were included in the study for 13 years. In 62.5% of cases the donor for the transplantation was represented by an alive donor who was genetically related to the child, and by donors with cerebral death in 37.5% of cases. The survival rate of transplanted patients in the group was 88.3% and survival graft 70%. Among medical complications acute infections were in 37.5% of cases, being the most common infection with Cytomegalovirus (20% of the children under study), fungal nfections (15%), urinary tract infections (9.67%). In 17.5% of the cases we could demonstrate hepatitic virus infections. The analysis of the group showed the death rate of 10% after almost exclusively infectious complications, only 1% of the death cases was caused by other factors. Conclusion. Infectious complications after renal transplantation in children remain one of the most severe problem being an important cause of exitus.

The aim of the investigation the improvement of rehabilitation measures for disabled children with pathology of SMA. 46 children at the age of 12 14 with pathology of SMA were at the investigation. Clinical, paraclinical, anthropometric laboratory and electromyographic investigations were the methods. The complex of physical exercises was worked out for each affected leg in monoparesis and in affected extremities in paraparises. While the investigation of generation of reactive oxygen species (ROS) in children s blood with residual stage of spinal poliomyelitis in the blood of healthy extremity (in monoparesis) 2.5 times increase of TBA-active products (TBA-AP) relatively the analogous rate of control (check) group children was observed. With the affected extremity, 4.2 times increase of investigated rate was detected. Activity of Superoxide Dismutase (SOD) altered in opposite irection. In the healthy extremities of patients activity of blood SOD was 2.09 times lower, and in the affected extremity only 1.20 times in the monoparesis and 1.55 times in the paraparesis, by comparison with analogous rate of control. Effectiveness of physical utilization directed to each affected group of muscle was studied. Anthropometric and myographic investigations showed stabilization of atrophic process in the muscle of their electrophysiologic rates. Results of the work are introduced into the practice of the 1st, 2nd and 3rd Republic Pediatric poliomyelitis hospital departments of the Ministry of Health of the Republic of Uzbekistan. Basic states are processed as the informative letters, which are sent to the primary units of healthcare for the usage in out-patient observation of the present patients community.

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