Disease with symptoms pt2

Entropion*The feeling that there's something in your eye. *Redness of the white part of your eye. *Eye irritation or pain. *Sensitivity to light and wind. *Watery eyes (excessive tearing). *Mucous discharge and eyelid crusting. *Decreased vision.

Eosinophilic esophagitisSymptoms in Adults: *Difficulty swallowing (dysphagia). *Food impaction. *Chest pain that is often centrally located and does not respond to antacids. *Persistent heartburn. *Upper abdominal pain. *No response to gastroesophageal reflux disease (GERD) medication. *Backflow of undigested food (regurgitation).

Symptoms in Children: *Difficulty feeding. *Vomiting. *Abdominal pain. *Difficulty swallowing (dysphagia). *Food impaction. *No response to GERD medication. *Failure to thrive (poor growth, malnutrition and weight loss).

Epicondylitis(lateral) or Tennis elbow*Pain and weakness may make it difficult to: *Shake hands. *Turn a doorknob. *Hold a coffee cup.

Epidermoid(Sebaceous) cyst*A small, round bump under the skin, usually on the face, trunk or neck. *A tiny blackhead plugging the central opening of the cyst. *A thick, yellow, foul-smelling material that sometimes drains from the cyst. *Redness, swelling and tenderness in the area, if inflamed or infected.

Epidermolysis bullosa*Fluid-filled blisters on the skin, especially on the hands and feet due to friction. *Deformity or loss of fingernails and toenails. *Internal blistering, including on the vocal cords, esophagus and upper airway. *Skin thickening on the palms and the soles of the feet. *Scalp blistering, scarring and hair loss (scarring alopecia). *Thin-appearing skin (atrophic scarring).

*Tiny white skin bumps or pimples (milia). *Dental problems, such as tooth decay from poorly formed enamel. *Difficulty swallowing(Dysphagia).

Epididymitis*A swollen, red or warm scrotum. *Testicle pain and tenderness, usually on one side. *Painful urination or an urgent or frequent need to urinate. *Discharge from the penis. *Painful intercourse or ejaculation. *A lump on the testicle. *Enlarged lymph nodes in the groin. *Pain or discomfort in the lower abdomen or pelvic area. *Blood in the semen. *Less commonly, fever.

Epidural hematoma or intracranial hematoma*Increasing headache. *Vomiting. *Drowsiness and progressive loss of consciousness. *Dizziness. *Confusion. *Unequal pupil size. *Slurred speech. *Increased blood pressure. *Lethargy. *Seizures. *Unconsciousness.

EpiglottitisSymptoms in children: *Fever. *Severe sore throat. *Abnormal, high-pitched sound when breathing in (stridor). *Difficult and painful swallowing. *Drooling. *Anxious, restless behavior. *Greater comfort when sitting up or leaning forward.

Symptoms in adults: *Severe sore throat. *Fever. *A muffled or hoarse voice. *Abnormal, high-pitched sound when breathing in (stridor). *Difficulty breathing. *Difficulty swallowing.

Erythema infectiosum or Parvovirus infection-

Parvovirus symptoms in children *Fever. *Upset stomach. *Headache. *Runny nose. *Distinctive facial rash.

Parvovirus symptoms in adults: *Joint soreness, lasting days to weeks. Joints most commonly affected are the hands, wrists, knees and ankles.

Erythema multiforme major or Stevens-Johnson syndrome *Facial swelling. *Tongue swelling. *Hives. *Skin pain. *A red or purple skin rash that spreads within hours to days. *Blisters on your skin and the mucous membranes of your mouth, nose, eyes and genitals. *Shedding of your skin. *Fever. *Sore mouth and throat. *Fatigue. *Cough. *Burning eyes.

Esophageal cancer*Difficulty swallowing (dysphagia). *Weight loss without trying. *Chest pain, pressure or burning *Worsening indigestion or heartburn. *Coughing or hoarseness.

Esophageal spasms*Squeezing pain in your chest, often intense, which you might mistake for heart pain (angina). *Difficulty swallowing (dysphagia). *The feeling that an object is stuck in your throat (globus). *The return of food and liquids back up your esophagus (regurgitation).

Esophageal varices*Bleeding. *Vomiting blood. *Black, tarry or bloody stools. *Shock (in severe case).

Esophagitis*Difficult swallowing. *Painful swallowing. *Chest pain, particularly behind the breastbone, that occurs with eating. *Swallowed food becoming stuck in the esophagus (food impaction).

*Heartburn. *Acid regurgitation.

Essential thrombocythemia*Headache. *Dizziness or lightheadedness. *Chest pain. *Weakness. *Fainting. *Temporary vision changes. *Numbness or tingling of the hands and feet. *Redness, throbbing and burning pain in the hands and feet (erythromelalgia). *Mildly enlarged spleen.

Bleeding may take the form of: *Nosebleeds. *Bruising. *Bleeding from your mouth or gums. *Bloody stool. *Weakness or numbness of your face, arm or leg, usually on one side of your body. *Difficulty speaking or understanding speech (aphasia). *Blurred, double or decreased vision.

Essential tremor*Begin gradually. *Worsen with movement. *Usually occur in the hands first, affecting one hand or both hands. *Can include a "yes-yes" or "no-no" motion of the head. *May be aggravated by emotional stress, fatigue, caffeine or extremes of temperature.

Exercise head achesPrimary exercise headaches: * Are usually described as throbbing. *Occur during or after strenuous exercise. *Affect both sides of the head in most cases.

Secondary exercise headaches: *The same symptoms as primary exercise headaches. *Vomiting. *Loss of consciousness. *Double vision. *Neck rigidity.

Exercised-induced asthma or Exercised-induced bronchoconstriction*Coughing. *Wheezing. *Shortness of breath.

*Chest tightness or pain. *Fatigue during exercise. *Poorer than expected athletic performance. *Feeling out of shape even when you're in good physical shape. *Avoidance of activity (a sign primarily among young children).

Extrasystoles or Premature ventricular contractions or PVCs or Ventricular premature beats*May feel an odd sensation in your chest, such as: *Flip-flops. *Fluttering. *Pounding or jumping. *Skipped beats or missed beats. *Increased awareness of your heartbeat.

Eye floaters*Spots in your vision that appear as dark specks or knobby, transparent strings of floating material. *Spots that move when you move your eyes, so when you try to look at them, they move quickly out of your visual field. *Spots that are most noticeable when you look at a plain bright background, such as a blue sky or a white wall. *Spots that eventually settle down and drift out of the line of vision.

Eye melanoma*A growing dark spot on the iris. *A sensation of flashing lights. *A change in the shape of the dark circle (pupil) at the center of your eye. *Poor or blurry vision in one eye. *Loss of peripheral vision. *Sensation of flashes and specs of dust in your vision (floaters).

Eyestrain*Sore, tired, burning or itching eyes. *Watery eyes. *Dry eyes. *Blurred or double vision. *Headache. *Sore neck. *Sore back. *Shoulder pain. *Increased sensitivity to light. *Difficulty focusing.

Factitious disorder*Clever and convincing medical problems. *Frequent hospitalizations. *Vague or inconsistent symptoms. *Conditions that get worse for no apparent reason.

*Conditions that don't respond as expected to standard therapies. *Eagerness to have frequent testing or risky operations. *Extensive knowledge of medical terms and diseases. *Seeking treatment from many different doctors or hospitals, which may include using a fake name. *Having few visitors when hospitalized. *Reluctance to allow health professionals to talk to family or friends or to other health care providers. *Arguing with hospital staff. *Frequent requests for pain relievers or other medications.

Factor V Leiden*never develop signs or symptoms. However, the first indication that you have the disorder may be the development of a blood clot (thrombosis).

Fallen arches or flat feet*foot pain, particularly in the heel or arch area. Pain may worsen with activity. Swelling along the inside of the ankle.

Familial Mediterranean fever pr Familial paroxysmal peritonitis*Fever. *Abdominal pain. *Chest pain. *Achy, swollen joints. *Constipation followed by diarrhea. *A red rash on your legs, especially below your knees. *Muscle aches. *A swollen, tender scrotum.

Farsightedness (hyperopia)*Nearby objects may appear blurry. *You need to squint to see clearly. *You have eyestrain, including burning eyes, and aching in or around the eyes. *You experience general eye discomfort or a headache after a prolonged interval of conducting close tasks, such as reading, writing, computer work or drawing.

Febrile seizure*Have a fever higher than 100.4 F (38.0 C). *Lose consciousness. *Shake or jerk arms and legs.

Fecal incontinencemay be accompanied by other bowel problems, such as: *Diarrhea. *Constipation. *Gas and bloating. female sexual dysfunction*Your desire to have sex is low or absent. *You can't maintain arousal during sexual activity, or you don't become aroused despite a desire

to have sex. *You can't experience an orgasm. *You have pain during sexual contact.

Fetal alcohol syndromePhysical defects: *Distinctive facial features, including wide-set eyes, an exceptionally thin upper lip, a short, upturned nose, and a smooth skin surface between the nose and upper lip. *Deformities of joints, limbs and fingers. *Slow physical growth before and after birth. *Vision difficulties or hearing problems. *Small head circumference and brain size. *Heart defects and problems with kidneys and bones.

Brain and central nervous system problems: *Poor coordination or balance. *Intellectual disability, learning disorders and delayed development. *Poor memory. *Trouble with attention and with processing information. *Difficulty with reasoning and problem-solving. *Difficulty identifying consequences of choices. *Poor judgment skills. *Jitteriness or hyperactivity. *Rapidly changing moods.

Social and behavioral issues: *Difficulty in school. *Trouble getting along with others. *Poor social skills. *Trouble adapting to change or switching from one task to another. *Problems with behavior and impulse control. *Poor concept of time. *Problems staying on task. *Difficulty planning or working toward a goal.

Fetal macrosomia*Large fundal height. * Excessive amniotic fluid (polyhydramnios).

Fever*Sweating. *Shivering. *Headache. *Muscle aches. *Loss of appetite. *Dehydration. *General weakness.

High fevers between 103 F (39.4 C) and 106 F (41.1 C) may cause:

*Hallucinations. *Confusion. *Irritability. *Convulsions. *Dehydration.

Fibroadenomassolid breast lumps or masses that usually are: *Round with distinct borders. *Easily moved. *Firm or rubbery. *Painless.

Fibrocystic breasts*Breast lumps or areas of thickening that tend to blend into the surrounding breast tissue. *Generalized breast pain or tenderness. *Fluctuating size of breast lumps. *Green or dark brown nonbloody nipple discharge that tends to leak without pressure or squeezing. *Changes that occur in both breasts, rather than just one. *Monthly increase in breast pain or lumpiness from midcycle (ovulation) to just before your period.

Fibromuscular dysplasiaKidney signs and symptoms: If the arteries to your kidneys (renal arteries) are affected, you may have: *High blood pressure. *Tissue damage in your kidney (ischemic renal atrophy). *Chronic kidney failure, rarely.

Brain signs and symptoms If the arteries to your brain (carotid arteries) are affected, you may have: *Headache. *Dizziness. *Blurred vision or temporary loss of vision. *Pulsating ringing in your ears (tinnitus). *Neck pain. *Chronic headaches. *Facial weakness or numbness.

Abdominal signs and symptoms If the arteries to your abdomen (mesenteric arteries) are affected, you may have: *Abdominal pain after eating. *Unintended weight loss.

Arm and leg signs and symptoms If the arteries to your arms or legs (peripheral arteries) are affected, you may have: *Discomfort when moving your arms, legs, hands or feet. *Cold limbs.

*Weakness. *Numbness. *Skin changes in color or appearance.

Fibromyalgia*Widespread pain. *Fatigue. *Cognitive difficulties. *Depression, headaches, and pain or cramping in the lower abdomen.

Fibromyomas or uterine fibroids or leiomyomas or myomas*Heavy menstrual bleeding. *Prolonged menstrual periods — seven days or more of menstrual bleeding. *Pelvic pressure or pain. *Frequent urination. *Difficulty emptying your bladder. *Constipation. *Backache or leg pains.

Fibrous dysplasia*Bone pain. *Bone deformities. *Fractures. *Nerve entrapment. *Very early puberty. *Thyroid gland problems. *Light brown spots on the skin.

Flatulence or gas & gas pains*Voluntary or involuntary passing of gas, either as belches or as flatus. *Sharp, jabbing pains or cramps in your abdomen. These pains may occur anywhere in your abdomen and can change locations quickly and get better quickly. *A 'knotted' feeling in your abdomen. *Swelling and tightness in your abdomen (bloating).

Flaviviruses or Viral haemorrhagic fevers*High fever. *Fatigue. *Dizziness. *Muscle, bone or joint aches. *Weakness. *Shock. *Nervous system malfunctions. *Coma. *Delirium. *Kidney failure. *Liver failure.

Bleeding may occur:

*Under the skin. *In internal organs. *From the mouth, eyes or ears.

Flu or Influenza*Fever over 100 F (38 C). *Aching muscles, especially in your back, arms and legs. *Chills and sweats. *Headache. *Dry cough. *Fatigue and weakness. *Nasal congestion.

Fluid around the heart or pericardial effusion*Shortness of breath or difficulty breathing (dyspnea). *Discomfort when breathing while lying down (orthopnea). *Chest pain, usually behind the breastbone or on the left side of the chest that often feels worse when you breathe and feels better when you are sitting up, rather than lying down. *Cough. *Low-grade fever. *Rapid heart rate.

Folate deficiency anemia or Vitamin deficiency anemia include*Fatigue. *Shortness of breath. *Dizziness. *Pale or yellowish skin. *Irregular heartbeats. *Weight loss. *Numbness or tingling in your hands and feet. *Muscle weakness. *Personality changes. *Unsteady movements. *Mental confusion or forgetfulness.

Food allergy*Tingling or itching in the mouth. *Hives, itching or eczema. *Swelling of the lips, face, tongue and throat or other parts of the body. *Wheezing, nasal congestion or trouble breathing. *Abdominal pain, diarrhea, nausea or vomiting. *Dizziness, lightheadedness or fainting.

Food poisoning or Food borne illness*Nausea. *Vomiting. *Watery diarrhea. *Abdominal pain and cramps.

*Fever.

Frontal lobe seizures or Frontal lobe epilepsy*Head and eye movement to one side. *Complete or partial unresponsiveness or difficulty speaking. *Explosive screams, including profanities, or laughter. *Abnormal body posturing, such as one arm extending while the other flexes, as if the person is posing like a fencer. *Repetitive movements, such as rocking, bicycle pedaling or pelvic thrusting.

Frontotemporal dementia (frontotemporal lobar degeneration)Behavioral changes: *Increasingly inappropriate actions. *Loss of empathy and other interpersonal skills. *Lack of judgment and inhibition Apathy. *Repetitive compulsive behavior. *A decline in personal hygiene. *Changes in eating habits, predominantly overeating. *Lack of awareness of thinking or behavioral changes.

Speech and language problems: *Impairment or loss of speech and language difficulties.

Movement disorders: *Tremor. *Rigidity. *Muscle spasms. *Poor coordination. *Difficulty swallowing. *Muscle weakness.

Frostbite*At first, cold skin and a prickling feeling. *Numbness. *Red, white, bluish-white or grayish-yellow skin. *Hard or waxy-looking skin. *Clumsiness due to joint and muscle stiffness. *Blistering after rewarming, in severe cases.

Fuchs' dystrophy*Glare, which is an early symptom and reduces contrast perception or affects vision in low light. *Blurred vision, which occurs in the morning after awakening and gradually improves during the day. As the disease progresses, vision can take longer to improve or may not improve. *Distorted vision, sensitivity to light, difficulty seeing at night and seeing halos around light. *Painful, tiny blisters on the surface of your cornea. *A cornea that looks cloudy or hazy.

Funnel chest or pectus excavatum*Decreased exercise tolerance.

*Rapid heartbeat or heart palpitations. *Recurrent respiratory infections. *Wheezing or coughing. *Chest pain. *Heart murmur. *Fatigue.

Generalized anxiety disorder(GAD)*Persistent worrying or obsession about small or large concerns that's out of proportion to the impact of the event. *Inability to set aside or let go of a worry. *Inability to relax, restlessness, and feeling keyed up or on edge. *Difficulty concentrating, or the feeling that your mind "goes blank". *Worrying about excessively worrying. *Distress about making decisions for fear of making the wrong decision. *Carrying every option in a situation all the way out to its possible negative conclusion. *Difficulty handling uncertainty or indecisiveness.

Physical signs and symptoms may include: *Fatigue. *Irritability. *Muscle tension or muscle aches. *Trembling, feeling twitchy. *Being easily startled. *Trouble sleeping. *Sweating. *Nausea, diarrhea or irritable. *bowel syndrome. *Headaches.

Galactorrhea*Persistent or intermittent milky nipple discharge that has no trace of blood. *Nipple discharge involving multiple milk ducts. *Spontaneously leaked or manually expressed nipple discharge. *One or both breasts affected. *Absent or irregular menstrual periods. *Headaches or vision problems.

Gallbladder inflammation or cholecystitis*Severe pain in your upper right abdomen. *Pain that radiates from to your right shoulder or back. *Tenderness over your abdomen when it's touched. *Nausea. *Vomiting. *Fever.

Gallstones*Sudden and rapidly intensifying pain in the upper right portion of your abdomen. *Sudden and rapidly intensifying pain in the center of your abdomen, just below your

breastbone. *Back pain between your shoulder blades. *Pain in your right shoulder.

Ganglion cysts*Ganglion cysts most commonly develop along the tendons or joints of your wrists or hands and ankles and feet. *cysts are round or oval and usually measure less than an inch in diameter. *Ganglion cysts usually are painless. However, if a cyst presses on a nerve — even if the cyst is too small to form a noticeable lump — it can cause pain, tingling, numbness or muscle weakness.

Gangrene*Skin discoloration — ranging from pale to blue, purple, black, bronze or red, depending on the type of gangrene you have. *A clear line between healthy and damaged skin. *Severe pain followed by a feeling of numbness. *A foul-smelling discharge leaking from a sore. *The affected tissue is swollen and very painful. *You're running a fever and feel unwell. *Low blood pressure. *Fever, possibly, though temperature may also run lower than the normal 96.8 F (36 C). *Rapid heart rate. *Lightheadedness. *Shortness of breath. *Confusion.

Gastric cancer or stomach cancer may include: *Fatigue. *Feeling bloated after eating. *Feeling full after eating small amounts of food. *Heartburn that is severe and persistent. *Indigestion that is severe and unrelenting. *Nausea that is persistent and unexplained. *Stomach pain. *Vomiting that is persistent. *Weight loss that is unintentional.

Gastritis*Gnawing or burning ache or pain (indigestion) in your upper abdomen that may become either worse or better with eating. *Nausea. *Vomiting. *A feeling of fullness in your upper abdomen after eating.

Gaucher's disease Glucoserebrosidase deficiency*Abdominal complaints. Because the liver and especially the spleen can enlarge dramatically, the abdomen can become painfully distended.

*Skeletal abnormalities. Gaucher's disease can weaken bone, increasing the risk of painful fractures. It can also interfere with the blood supply to your bones, which can cause portions of the bone to die. *Blood disorders. A decrease in healthy red blood cells (anemia) can result in severe fatigue.

Gaucher's disease also affects the cells responsible for clotting, which can cause easy bruising and nosebleeds.

Genital herpes*Pain or itching that begins within two to 10 days after exposure to an infected sexual partner. *Small red bumps or tiny white blisters, which may appear several days later. *Ulcers that form when the blisters rupture and ooze or bleed. *Scabs that form as the ulcers heal.

German measles or three-day measles or Rubella*Mild fever of 102 F (38.9 C) or lower. *Headache. *Stuffy or runny nose. *Inflamed, red eyes. *Enlarged, tender lymph nodes at the base of the skull, the back of the neck and behind the ears. *A fine, pink rash that begins on the face and quickly spreads to the trunk and then the arms and legs, before disappearing in the same sequence. *Aching joints, especially in young women.

Giardiasis*Watery, sometimes foul-smelling diarrhea that may alternate with soft, greasy stools. *Fatigue or malaise. *Abdominal cramps and bloating *Belching gas with a bad taste. *Nausea. *Weight loss.

Gilbert's syndrome*Illness, such as a cold or the flu. *Fasting or eating a very low-calorie diet. *Dehydration. *Menstruation. *Stress. *Strenuous exercise. *Lack of sleep.

Gingivitis*Swollen gums. *Soft, puffy gums. *Receding gums. *Occasionally, tender gums. *Gums that bleed easily when you brush or floss, sometimes seen as redness or pinkness on your brush or floss.

*A change in the color of your gums from a healthy pink to dusky red. *Bad breath.

Gingivitis or trench mouth or necrotizing ulcerative gingivitis (NUG)*Severe gum pain. *Bleeding from gums when they're pressed even slightly. *Red or swollen gums. *Pain when eating or swallowing. *Gray film on your gums. *Crater-like sores (ulcers) between your teeth and on your gums. *Foul taste in your mouth. *Bad breath. *Fever and fatigue (malaise). *Swollen lymph nodes around your head, neck or jaw.

GlaucomaPrimary open-angle glaucoma signs and symptoms include: *Gradual loss of peripheral vision, usually in both eyes. *Tunnel vision in the advanced stages.

Acute angle-closure glaucoma signs and symptoms include: *Eye pain. *Nausea and vomiting (accompanying the severe eye pain). *Sudden onset of visual disturbance, often in low light. *Blurred vision. *Halos around lights. *Reddening of the eye.

Globoid cell leukodystrophy or Krabbe's diseaseInfants: *Feeding difficulties. *Unexplained crying. *Extreme irritability. *Fever with no sign of infection. *Declines in alertness. *Delays in typical developmental milestones. *Muscle spasms. *Loss of head control. *Frequent vomiting. *Seizures. *Loss of developmental abilities. *Progressive loss of hearing and sight. *Rigid, constricted muscles. *Stiff, fixed posture. *Progressive loss of ability to swallow and breathe.

Adults: *Progressive loss of vision.

*Difficulty walking (ataxia) *Decline in thinking skills. *Loss of manual dexterity. *Muscles weakness.

Glomerulonephritis*Pink or cola-colored urine from red blood cells in your urine (hematuria). *Foamy urine due to excess protein (proteinuria). *High blood pressure (hypertension). *Fluid retention (edema) with swelling evident in your face, hands, feet and abdomen. *Fatigue from anemia or kidney failure.

Golfer's elbow*Pain and tenderness on the inner side of your elbow. Sometimes the pain extends along the inner side of your forearm. *Stiffness. Your elbow may feel stiff, and it may hurt to make a fist. *Weakness in your hands and wrists. *Numbness or tingling.

Gonorrheagonorrhea infection in men include: *Painful urination. *Pus-like discharge from the tip. of the penis. *Pain or swelling in one testicle.

Signs and symptoms of gonorrhea infection in women include: *Increased vaginal discharge. *Painful urination. *Vaginal bleeding between periods, such as after vaginal intercourse. *Abdominal pain. *Pelvic pain.

Gout*Intense joint pain. Gout usually affects the large joint of your big toe, but it can occur in your feet, ankles, knees, hands and wrists. *The pain is likely to be most severe within the first four to 12 hours after it begins. *Lingering discomfort. *Inflammation and redness. The affected joint or joints become swollen, tender, warm and red. *Limited range of motion. Decreased joint mobility may occur as gout progresses.

Grand mal seizures or generalized tonic-clonic seizure*Some people experience a warning feeling (aura). *Some people may cry out at the beginning of a seizure because the muscles around the vocal cords seize, forcing air out. *Loss of bowel and bladder control. *Unresponsiveness after convulsions. *Confusion. *Fatigue. *Severe headache.

Granuloma annulare*The lesion borders have a circular or semicircular shape, with a diameter up to 2 inches (5 centimeters). It occurs most commonly on the hands, feet, wrists and ankles of young adults, particularly women. *lesions over a large portion of their bodies — including the trunk, arms and legs. *Subcutaneous type of granuloma annulare produces a firm lump under the skin instead of a rash. The lump is usually less than 1.5 inches (3.8 centimeters) in diameter.

Graves' disease*Anxiety and irritability. *A fine tremor of your hands or fingers. *Heat sensitivity and an increase in perspiration or warm, moist skin. *Weight loss, despite normal eating habits. *Enlargement of your thyroid gland (goiter). *Change in menstrual cycles. *Erectile dysfunction or reduced libido. *Frequent bowel movements. *Bulging eyes (Graves' ophthalmopathy). *Thick, red skin usually on the shins or tops of the feet (Graves' dermopathy). *Rapid or irregular heartbeat (palpitations).

Greenstick fractures*The intense pain, swelling and obvious deformity typical of broken bones may be absent or minimal in mild greenstick fractures.

Group B strep diseaseEarly-onset group B strep disease: *Fever. *Difficulty feeding. *Lethargy.

Late-onset group B strep disease: *Difficulty breathing. *Fever. *Difficulty feeding. *Lethargy. *Irritability.

Growing pains*Usually cause an aching or throbbing feeling in the legs. *This pain often occurs in the front of the thighs, the calves or behind the knees. *Abdominal pain. *Headache.

Growth plate fracture*Pain and tenderness, particularly in response to pressure on the growth plate. *Inability to move the affected area or to put weight or pressure on the limb. *Warmth and swelling at the end of a bone, near a joint.

Gum disease or periodontitis*Swollen gums.

*Bright red or purplish gums. *Gums that feel tender when touched. *Gums that pull away from your teeth (recede), making your teeth look longer than normal. *New spaces developing between your teeth. *Pus between your teeth and gums. *Bad breath. *Bad taste in your mouth. *Loose teeth. *A change in the way your teeth fit together when you bite.

H. pylori infection*An ache or burning pain in your abdomen. *Abdominal pain that's worse when your stomach is empty. *Nausea. *Loss of appetite. *Frequent burping. *Bloating. *Unintentional weight loss.

H1N1 flu or Swine flu*Fever. *Cough. *Sore throat. *Runny or stuffy nose. *Body aches. *Headache. *Chills. *Fatigue. *Diarrhea. *Vomiting.

Hair-pulling disorder or trichotillomania*Repeatedly pulling your hair out, typically from your scalp, eyebrows or eyelashes, but can be from other body areas, and sites may vary over time. *An increasing sense of tension before pulling, or when you try to resist pulling. *A sense of pleasure or relief after the hair is pulled. *Shortened hair or thinned or bald areas on the scalp or other areas of your body, including sparse or missing eyelashes or eyebrows. *Preference for specific types of hair, rituals that accompany hair pulling or patterns of hair pulling. *Biting, chewing or eating pulled-out hair. *Playing with pulled-out hair or rubbing it across your lips or face.

Hairy cell leukemia*A feeling of fullness in your abdomen that may make it uncomfortable to eat more than a little at a time. *Fatigue.

*Easy bruising. *Recurring infections. *Weakness. *Weight loss.

Hammertoe and mallet toe- *feature an abnormal bend in the joints of one or more of your toes. *Moving the affected toe may be difficult or painful. *Corns and calluses can result from the toe rubbing against the inside of your shoes.

Hamstring injury*A sudden, sharp pain in the back of your thigh. *A popping or tearing sensation. *Swelling and tenderness. *Bruising or discoloration along the back of your leg, as well as muscle weakness or an inability to put weight on your injured leg.

Hand-foot-and-mouth disease*Fever. *Sore throat. *Feeling of being unwell (malaise). *Painful, red, blister-like lesions on the tongue, gums and inside of the cheeks. *A red rash, without itching but sometimes with blistering, on the palms, soles and sometimes the buttocks. *Irritability in infants and toddlers. *Loss of appetite.

Hangover*Fatigue and weakness. *Thirst. *Headaches and muscle aches. *Nausea, vomiting or stomach pain. *Poor or decreased sleep. *Increased sensitivity to light and sound. *Dizziness or a sense of the room spinning. *Shakiness. *Decreased ability to concentrate. *Mood disturbances, such as depression, anxiety and irritability. *Rapid heartbeat.

Hantavirus pulmonary syndrome*Fever and chills. *Headaches and muscle aches. *Vomiting, diarrhea or abdominal pain. *A cough that produces secretions. *Shortness of breath. *Fluid accumulating within the lungs. *Low blood pressure. *Reduced heart efficiency.

Head lice-

*Itching. *lice on scalp. *Lice eggs (nits) on hair shafts.

Hearing loss*Muffling of speech and other sounds. *Difficulty understanding words, especially against background noise or in a crowd of people. *Trouble hearing consonants. *Frequently asking others to speak more slowly, clearly and loudly. *Needing to turn up the volume of the television or radio. *Withdrawal from conversations. *Avoidance of some social settings.

Heart attack*Pressure, tightness, pain, or a squeezing or aching sensation in your chest or arms that may spread to your neck, jaw or back. *Nausea, indigestion, heartburn or abdominal pain. *Shortness of breath. *Cold sweat. *Fatigue. *Lightheadedness or sudden dizziness.

Heart murmur*Skin that appears blue, especially on your fingertips and lips. *Swelling or sudden weight gain. *Shortness of breath. *Chronic cough. *Enlarged liver. *Enlarged neck veins. *Poor appetite and failure to grow normally (in infants). *Heavy sweating with minimal or no exertion. *Chest pain. *Dizziness. *Fainting.

Heartburn or Indigestion*A burning pain in the chest that usually occurs after eating and may occur at night. *Pain that worsens when lying down or bending over.

Heat exhaustion*Cool, moist skin with goose bumps when in the heat. *Heavy sweating. *Faintness. *Dizziness. *Fatigue. *Weak, rapid pulse. *Low blood pressure upon standing. *Muscle cramps.

*Nausea. *Headache.

Heat rash or prickly heat and miliaria*Appears in Skin folds and where clothing causes friction. *In infants, the rash is mainly found on the neck, shoulders and chest. It can also show up in the armpits, elbow creases and groin.

Heatstroke*High body temperature. A body temperature of 104 F (40 C) or higher is the main sign of heatstroke. *Altered mental state or behavior. Confusion, agitation, slurred speech, irritability, delirium, seizures and coma. *Alteration in sweating. *Nausea and vomiting. *Flushed skin. *Rapid & shallow breathing. *Racing heart rate. *Headache.

Heavy menstrual periods or menorrhagia*Soaking through one or more sanitary pads or tampons every hour for several consecutive hours. *Needing to use double sanitary protection to control your menstrual flow. *Needing to wake up to change sanitary protection during the night. *Bleeding for longer than a week. *Passing blood clots with menstrual flow for more than one day. *Restricting daily activities due to heavy menstrual flow. *Symptoms of anemia, such as tiredness, fatigue or shortness of breath.

Heel pain or Plantar fasciitis- *causes a stabbing pain in the bottom of your foot near the heel. *The pain is usually worst with the first few steps after awakening, although it can also be triggered by long periods of standing or getting up from a seated position.

Hemangioma*starts out as a flat red mark anywhere on the body, most often on the face, scalp, chest or back. *the red mark grows rapidly and becomes a spongy mass that protrudes from the skin.

Hemifacial spasm*muscles on one side of your face twitch involuntarily.

Hereditary hemochromatosis*Joint pain. *Fatigue. *Weakness. *Joint pain. *Diabetes. *Loss of sex drive (libido). *Impotence.

*Heart failure.

Hemolytic uremic syndrome(HUS)*Bloody diarrhea. *Vomiting. *Abdominal pain. *Pale skin tone. *Fatigue and irritability. *Fever, usually not high and may not be present at all. *Blood in the urine. *Small, unexplained bruises or bleeding from the nose and mouth. *Decreased urination or blood in the urine. *Swelling of the face, hands, feet or entire body. *Confusion.

Hemophilia*Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work. *Many large or deep bruises. *Unusual bleeding after vaccinations. *Pain, swelling or tightness in your joints. *Blood in your urine or stool. *Nosebleeds without a known cause.

In infants, unexplained irritability Emergency signs and symptoms of hemophilia include: *Sudden pain, swelling and warmth in large joints, such as knees, elbows, hips and shoulders, and in your arm and leg muscles. *Bleeding from an injury, especially if you have a severe form of hemophilia. *Painful, prolonged headache. *Repeated vomiting. *Extreme fatigue. *Neck pain. *Double vision.

Hemorrhoids or piles*Painless bleeding during bowel movements — you might notice small amounts of bright red blood on your toilet tissue or in the toilet bowl. *Itching or irritation in your anal region. *Pain or discomfort. *Swelling around your anus. *A lump near your anus, which may be sensitive or painful. *Leakage of feces.

Henoch-Schonlein purpura*Rash (purpura). Reddish-purple spots, which look like bruises,The rash develops mainly on the buttocks, legs and feet, but it can also appear on the arms, face and trunk and may be worse in areas of pressure, such as the sock line and waistline. *Swollen, sore joints (arthritis).

*Gastrointestinal symptoms, such as abdominal pain, nausea, vomiting or bloody stools. *kidney involvement.

Hepatitis A*Fatigue. *Nausea and vomiting. *Abdominal pain or discomfort, especially in the area of your liver on your right side beneath your lower ribs. *Clay-colored bowel movements *Loss of appetite. *Low-grade fever. *Dark urine. *Joint pain. *Yellowing of the skin and eyes (jaundice).

Hepatitis B*Abdominal pain. *Dark urine. *Fever. *Joint pain. *Loss of appetite. *Nausea and vomiting. *Weakness and fatigue. *Yellowing of your skin and the whites of your eyes (jaundice).

Hepatitis C*Fatigue. *Nausea or poor appetite. *Stomach pain. *Dark-colored urine. *Yellow discoloration in the skin and eyes (jaundice). *Fever. *Muscle and joint pains.

Signs and symptoms of chronic infection: *Bleeding easily. *Bruising easily. *Itchy skin. *Fluid accumulation in your abdomen (ascites). *Swelling in your legs. *Weight loss. *Confusion, drowsiness and slurred speech (hepatic encephalopathy). *Spider-like blood vessels on your skin (spider angiomas).

Hepatocellular carcinoma or liver cancer*Losing weight without trying. *Loss of appetite. *Upper abdominal pain.

*Nausea and vomiting. *General weakness and fatigue. *Abdominal swelling. *Yellow discoloration of your skin and the whites of your eyes (jaundice). *White, chalky stools.

Hereditary hemorrhagic telangiectasia or HHT or Osler-Weber-Rendu syndrome*Bleeding. *don't allow for adequate oxygen levels in the blood, and can increase your risk of brain infections and stroke. *Nosebleeds and bleeding within the intestines can also lead to anemia.

Hereditary nonpolyposis colorectal cancer (HNPCC) or Lynch syndrome*Colon cancer that occurs at a younger age, especially before age 50. *A family history of colon cancer that occurs at a young age. *A family history of cancer that affects the uterus (endometrial cancer). *A family history of other related cancers, including ovarian cancer, kidney cancer, stomach cancer, small intestine cancer, liver cancer, sweat gland cancer (sebaceous carcinoma) and other cancers.

Hereditary progressive arthro-ophthalmopathy or Stickler syndrome*Eye problems. In addition to severe nearsightedness, children who have Stickler syndrome often experience cataracts, glaucoma and retinal detachments. *Hearing difficulties. The extent of hearing loss varies among people who have Stickler syndrome. It usually affects the ability to hear high frequencies. *Bone and joint abnormalities. Children who have Stickler syndrome often have overly flexible joints and are more likely to develop abnormal curvatures of the spine, such as scoliosis.

Osteoarthritis can begin in adolescence.

Herpes zoster or Shingles*Pain, burning, numbness or tingling. *Sensitivity to touch. *A red rash that begins a few days after the pain. *Fluid-filled blisters that break open and crust over. *Itching. *Fever. *Headache. *Sensitivity to light. *Fatigue.

Herpes zoster oticus or Ramsay Hunt syndrome*A painful red rash with fluid-filled blisters on, in and around one ear. *Facial weakness or paralysis on the same side as the affected ear. *Ear pain. *Hearing loss. *Ringing in your ears (tinnitus). *Difficulty closing one eye. *A sensation of spinning or moving (vertigo).

*A change in taste perception or loss of taste.

Hiccups*The characteristic sound of a hiccup is the only sign. *Sometimes the only symptom is a slight tightening sensation in your chest, abdomen or throat that precedes the sound.

Hidradenitis suppurativa*Blackheads. *Red, tender bumps. These bumps, or lesions, often enlarge, break open and drain pus. The drainage may have an unpleasant odor. *Itching, burning and excessive sweating may accompany the bumps. *Painful, pea-sized lumps. *Leaking bumps or sores. *These open wounds heal very slowly, if at all, often leading to scarring and the development of tunnels under the skin.

High blood pressure or Hypertension*headaches, shortness of breath or nosebleeds.

High-flow priapismIschemic priapism: *Unwanted erection lasting more than four hours. *Unwanted erection off and on for several hours (stuttering priapism). *Rigid penile shaft, but usually soft tip of penis (glans). *Usually painful or tender penis.

Nonischemic priapism*Unwanted erection lasting at least four hours. *Erect but not rigid penile shaft.

Hip fracture*Inability to move immediately after a fall. *Severe pain in your hip or groin. *Inability to put weight on your leg on the side of your injured hip. *Stiffness, bruising and swelling in and around your hip area. *Shorter leg on the side of your injured hip. *Turning outward of your leg on the side of your injured hip.

Hip labral tears*A locking, clicking or catching sensation in your hip joint. *Pain in your hip or groin. *Stiffness or limited range of motion in your hip joint.

Hirsutism*stiff and pigmented body hair, appearing on the body where women don't commonly have hair — primarily the face, chest and back. *Deepening voice. *Balding. *Acne. *Decrease in breast size.

*Enlargement of the clitoris.

Histoplasmosis*Fever. *Chills. *Headache. *Muscle aches. *Dry cough. *Chest discomfort.

HIV(Human immuno virus) or AIDS(Acquired immuno deficiency syndrome)Primary infection: *Fever. *Headache. *Muscle aches. *Rash. *Chills. *Sore throat. *Mouth or genital ulcers. *Swollen lymph glands, mainly on the neck. *Joint pain. *Night sweats. *Diarrhea.

Clinical latent infection: *persistent swelling of lymph nodes.

Early symptomatic HIV infection: *Fever. *Fatigue. *Swollen lymph nodes — often one of the first signs of HIV infection. *Diarrhea. *Weight loss. *Cough. *Shortness of breath.

Progression to AIDS: *Soaking night sweats. *Shaking chills or fever higher than 100 F (38 C) for several weeks. *Cough. *Shortness of breath. *Chronic diarrhea. *Persistent white spots or unusual lesions on your tongue or in your mouth *Headaches. *Persistent, unexplained fatigue. *Blurred and distorted vision. *Weight loss. *Skin rashes or bumps.

Hoarse voice or Laryngitis-

*Hoarseness. *Weak voice or voice loss. *Tickling sensation and rawness of your throat. *Sore throat. *Dry throat. *Dry cough.

Hodgkin's lymphoma or Hodgkin's disease*Painless swelling of lymph nodes in your neck, armpits or groin. *Persistent fatigue. *Fever and chills. *Night sweats. *Unexplained weight loss — as much as 10 percent or more of your body weight. *Loss of appetite. *Itching. *Increased sensitivity to the effects of alcohol or pain in your lymph nodes after drinking alcohol.

Hordeolum or Sty*A red lump on your eyelid that is similar to a boil or a pimple. *Eyelid pain. *Eyelid swelling. *Tearing.

Horner syndrome or Horner-Bernard syndrome or oculosympathetic palsy*A persistently small pupil (miosis). *A notable difference in pupil size between the two eyes (anisocoria). *Little or delayed opening (dilation) of the affected pupil in dim light. *Drooping of the upper eyelid (ptosis). *Slight elevation of the lower lid, sometimes called upside-down ptosis. *Little or no sweating (anhidrosis) either on the entire side of the face or an isolated patch of skin on the affected side.

Hot flash*A sudden feeling of warmth spreading through your upper body and face. *A flushed appearance with red, blotchy skin. *Rapid heartbeat. *Perspiration, mostly on your upper body. *Feeling chilled as the hot flash subsides.

Human papillomavirus (HPV)*Genital warts may appear as flat lesions, small cauliflower-like bumps or tiny stem-like protrusions. In women, genital warts appear most commonly on the vulva,anus,vagina,cervix. *In men, genital warts may appear on the penis and scrotum or around the anus. *Common warts appear as rough, raised bumps that usually occur on the hands, fingers or elbows.

*Plantar warts are hard, grainy growths that usually appear on the heels or balls of your feet, areas that feel the most pressure. These warts may cause discomfort or pain. *Flat warts are flat-topped, slightly raised lesions darker than your regular skin color. They usually appear on your face, neck or on areas that have been scratched. *Cervical cancer.

Hunchback or kyphosis*Abnormally curved spine. *Back pain. *Stiffness.

Hunter syndrome*Delayed development, such as late walking or talking. *Changing facial features, including thickening of the lips, tongue and nostrils. *A broad nose and flared nostrils. *Claw-like hands. *A protruding tongue. *Abnormal bone size or shape and other skeletal irregularities. *Enlarged internal organs, such as the liver and spleen, resulting in a distended abdomen. *Respiratory difficulties including sleep apnea, a condition in which breathing intermittently stops during sleep. *Cardiovascular disorders, such as progressive thickening of heart valves, high blood pressure (hypertension) and obstruction of blood vessels. *Vision damage or loss from degeneration of cells that capture light and buildup of cellular debris in the brain causing pressure on the optic nerve and eye. *Progressive loss of hearing. *Aggressive behavior. *Stunted growth. *Joint stiffness. *Diarrhea. *Carpal tunnel syndrome. *Sleep apnea.

Huntington's syndromeMovement disorders: *Involuntary jerking or writhing movements (chorea). *Muscle problems, such as rigidity or muscle contracture (dystonia). *Slow or abnormal eye movements. *Impaired gait, posture and balance. *Difficulty with the physical production of speech or swallowing. *Impairments in voluntary movements — rather than the involuntary movements — may have a greater impact on a person's ability to work, perform daily activities, communicate and remain independent.

Cognitive disorders: *Difficulty organizing, prioritizing or focusing on tasks. *Lack of flexibility or the tendency to get stuck on a thought, behavior or action (perseveration).

*Lack of impulse control that can result in outbursts, acting without thinking and sexual promiscuity. *Lack of awareness of one's own behaviors and abilities. *Slowness in processing thoughts or ''finding'' words. *Difficulty in learning new information.

Psychiatric disorders: *Feelings of irritability, sadness or apathy. *Social withdrawal. *Insomnia. *Fatigue and loss of energy. *Frequent thoughts of death, dying or suicide.

Symptoms of juvenile Huntington's diseaseBehavioral changes: *Loss of previously learned academic or physical skills. *Rapid, significant drop in overall school performance. *Behavioral problems.

Physical changes: *Contracted and rigid muscles that affect gait (especially in young children). *Changes in fine motor skills that might be noticeable in skills such as handwriting. *Tremors or slight involuntary movements. *Seizures.

Hurthle cell cancer or Hurthle cell carcinoma or oxyphilic cell carcinoma*A fast-growing lump in your neck, just below your Adam's apple. *Pain in your neck or throat. *Hoarseness or other changes in your voice. *Shortness of breath. *Swallowing difficulty.

Hutchinson-Gilford syndrome or Progeria*Slowed growth, with below-average height and weight. *Narrowed face, small lower jaw, thin lips and beaked nose. *Head disproportionately large for face. *Prominent eyes and incomplete closure of the eyelids. *Hair loss, including eyelashes and eyebrows. *Thinning, spotty, wrinkled skin. *Visible veins. *High-pitched voice. *Hardening and tightening of skin on trunk and extremities (similar to scleroderma). *Delayed and abnormal tooth formation. *Some hearing loss. *Loss of fat under the skin and loss of muscle mass. *Fragile bones. *Stiff joints. *Hip dislocation.

*Insulin resistance. *Severe progressive heart and blood vessel (cardiovascular) disease.

Hydrocele*Painless swelling of one or both testicles. *Discomfort from the heaviness of a swollen scrotum. *Pain generally increases with the size of the inflammation.

HydrocephalusInfants: Changes in the head: *An unusually large head. *A rapid increase in the size of the head. *A bulging or tense soft spot. (fontanel) on the top of the head.

Physical symptoms: *Vomiting. *Sleepiness. *Irritability. *Poor feeding. *Seizures. *Eyes fixed downward (sunsetting of the eyes). *Deficits in muscle tone and strength, responsiveness to touch, and expected growth.

Toddlers and older children: Physical symptoms: *Headache. *Blurred or double vision.

Physical signs: *Abnormal enlargement of a toddler's head. *Sleepiness. *Difficulty remaining awake or waking up. *Nausea or vomiting. *Unstable balance. *Poor coordination. *Poor appetite. *Seizures.

Behavioral and cognitive changes: *Irritability. *Change in personality. *Problems with attention. *Decline in school performance. *Delays or problems with previously acquired skills, such as walking or talking.

Young and middle-aged adults: *Headache. *Difficulty in remaining awake or waking up. *Loss of coordination or balance.

*Loss of bladder control or a frequent urge to urinate. *Impaired vision. *Decline in memory, concentration and other thinking skills that may affect job performance.

Older adults: *Loss of bladder control or a frequent urge to urinate. *Memory loss. *Progressive loss of other thinking or reasoning skills. *Difficulty walking, often described as a shuffling gait or the feeling of the feet being stuck. *Poor coordination or balance. *Slower than normal movements in general.

Hypercalcemia*Excess calcium in your blood means your kidneys have to work harder to filter it out. This can cause excessive thirst and frequent urination. *Digestive system-Hypercalcemia can cause stomach upset, nausea, vomiting and constipation. *Bones and muscles-In most cases, the excess calcium in your blood was leached from your bones, which weakens them. This can cause bone pain. *muscle weakness. *Brain- Hypercalcemia can interfere with the way your brain works, resulting in confusion, lethargy and fatigue.

Hypereosinophilic syndrome (HES)*Skin symptoms include itching and rashes. *If your lungs are affected, you may be short of breath and have a cough.

Hyperglycemia in diabetesEarly signs and symptoms: *Frequent urination. *Increased thirst. *Blurred vision. *Fatigue. *Headache.

Later signs and symptoms: *Fruity-smelling breath. *Nausea and vomiting. *Shortness of breath. *Dry mouth. *Weakness. *Confusion. *Coma. *Abdominal pain.

Hyperhidrosis*Sweaty hands, feet, underarms and sometimes the face.

Hyperparathyroidism*Fragile bones that easily fracture (osteoporosis). *Kidney stones.

*Excessive urination. *Abdominal pain. *Tiring easily or weakness. *Depression or forgetfulness. *Bone and joint pain. *Frequent complaints of illness with no apparent cause. *Nausea, vomiting or loss of appetite.

Hyperthyroidism*Sudden weight loss, even when your appetite and the amount and type of food you eat remain the same or even increase. *Rapid heartbeat (tachycardia) — commonly more than 100 beats a minute — irregular heartbeat (arrhythmia) or pounding of your heart (palpitations). *Increased appetite. *Nervousness, anxiety and irritability. *Tremor — usually a fine trembling in your hands and fingers. *Sweating. *Changes in menstrual patterns. *Increased sensitivity to heat. *Changes in bowel patterns, especially more frequent bowel movements. *An enlarged thyroid gland (goiter), which may appear as a swelling at the base of your neck. *Fatigue, muscle weakness. *Difficulty sleeping. *Skin thinning. *Fine, brittle hair.

Hypoactive sexual desire disorder or low sex drive*Has no interest in any type of sexual activity, including masturbation. *Doesn't have sexual fantasies or thoughts, or only seldom has them. *Is bothered by her lack of sexual activity or fantasies.

Hypochondria*Having a long-term intense fear or anxiety about having a serious disease or health condition. *Worrying that minor symptoms or bodily sensations mean you have a serious illness. *Seeing doctors repeated times or having involved medical exams such as magnetic resonance imaging (MRI), echocardiograms or exploratory surgery. *Frequently switching doctors — if one doctor tells you that you aren't sick, you may not believe it and seek out other opinions. *Continuously talking about your symptoms or suspected diseases with family and friends. *Obsessively doing health research. *Frequently checking your body for problems, such as lumps or sores. *Frequently checking your vital signs, such as pulse or blood pressure. *Thinking you have a disease after reading or hearing about it.

Hypoglycemia*Heart palpitations. *Fatigue.

*Pale skin. *Shakiness. *Anxiety. *Sweating. *Hunger. *Irritability. *Tingling sensation around the mouth. *Crying out during sleep. *Confusion, abnormal behavior or both, such as the inability to complete routine tasks. *Visual disturbances, such as blurred vision. *Seizures. *Loss of consciousness.

Hyponatremia*Nausea and vomiting. *Headache. *Confusion. *Loss of energy and fatigue. *Restlessness and irritability. *Muscle weakness, spasms or cramps. *Seizures. *Coma.

Hypoparathyroidism*Tingling or burning (paresthesias) in your fingertips, toes and lips. *Muscle aches or cramps affecting your legs, feet, abdomen or face. *Twitching or spasms of your muscles, particularly around your mouth, but also in your hands, arms and throat. *Fatigue or weakness. *Painful menstruation. *Patchy hair loss, such as thinning of your eyebrows. *Dry, coarse skin. *Brittle nails. *Headaches. *Depression, mood swings. *Memory problems.

Hypopharyngeal cancer or throat cancer*A cough. *Changes in your voice, such as hoarseness. *Difficulty swallowing. *Ear pain. *A lump or sore that doesn't heal. *A sore throat. *Weight loss.

Hypopituitarism-

*Fatigue. *Weight loss. *Decreased sex drive. *Sensitivity to cold or difficulty staying warm. *Decreased appetite. *Facial puffiness. *Anemia. *Infertility. *Hot flashes, irregular or no periods, loss of pubic hair, and inability to produce milk for breast-feeding in women. *Decreased facial or body hair in men. *Short stature in children.

Hypoplastic left heart syndrome*Grayish-blue skin color (cyanosis). *Rapid, difficult breathing. *Poor feeding. *Cold hands and feet. *Being unusually drowsy or inactive. *shock.

Hypospadias*Opening of the urethra at a location other than the tip of the penis. *Downward curve of the penis (chordee). *Hooded appearance of the penis because only the top half of the penis is covered by foreskin. *Abnormal spraying during urination.

Hypotension or low blood pressure*Dizziness or lightheadedness. *Fainting (syncope). *Lack of concentration. *Blurred vision. *Nausea. *Cold, clammy, pale skin. *Rapid, shallow breathing. *Fatigue. *Depression. *Thirst.

Hypothyroidism*Fatigue. *Increased sensitivity to cold. *Constipation. *Dry skin. *Unexplained weight gain. *Puffy face. *Hoarseness.

*Muscle weakness. *Elevated blood cholesterol level. *Muscle aches, tenderness and stiffness. *Pain, stiffness or swelling in your joints. *Heavier than normal or irregular menstrual periods. *Thinning hair. *Slowed heart rate. *Depression. *Impaired memory.

Ice cream headache*Sharp, stabbing pain in the *forehead.

Pain that peaks about 20 to 60 seconds after it begins and goes away in about the same time. *Pain that rarely lasts longer than five minutes.

Ichthyosis vulgaris*Dry, scaly skin. *Tile-like, small scales. *Scales colored white, dirty gray or brown — with darker colored scales typically on darker skin. *Flaky scalp. *Deep, painful cracks in your skin.

Icterus Infant jaundice or Infant jaundice*Yellowing of the skin and the whites of the eyes.

Idiopathic intracranial hypertension or Pseudotumor cerebri*Moderate to severe headaches that may originate behind your eyes and worsen with eye movement. *Ringing in the ears that pulses in time with your heartbeat (pulsatile tinnitus). *Nausea, vomiting or dizziness. *Blurred or dimmed vision. *Brief episodes of blindness, lasting only a few seconds and affecting one or both eyes (visual obscurations). *Difficulty seeing to the side Double vision (diplopia). *Seeing light flashes (photopsia). *Neck, shoulder or back pain.

Idiopathic myelofibrosis or Myelofibrosis*Feeling tired, weak or short of breath, usually because of anemia. *Pain or fullness below your ribs on the left side, due to an enlarged spleen. *Pale skin. *Easy bruising. *Easy bleeding. *Excessive sweating during sleep (night sweats). *Fever. *Frequent infections. *Bone pain.

Idiopathic thrombocytopenic purpura (ITP)*Easy or excessive bruising (purpura) — your skin naturally bruises and bleeds more easily as you age, but this shouldn't be confused with ITP. *Superficial bleeding into your skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on your lower legs. *Prolonged bleeding from cuts. *Spontaneous bleeding from nose. *Bleeding gums, especially after dental work. *Blood in urine or stools. *Unusually heavy menstrual flow. *Fatigue.

Idiopathic toe walking or Toe walking in children*walking on the toes or the ball of the foot.

Impacted wisdom teeth*Red or swollen gums. *Tender or bleeding gums. *Jaw pain. *Swelling around the jaw. *Bad breath. *An unpleasant taste in your mouth. *Difficulty opening your mouth.

Impetigo*Involve red sores that quickly rupture, ooze for a few days and then form a yellowish-brown crust. *The sores usually occur around the nose and mouth.

Incompetent cervix or Cervical insufficiency*A sensation of pelvic pressure. *A backache. *Mild abdominal cramps. *A change in vaginal discharge. *Light vaginal bleeding.

Infant reflux or Infant acid reflux*Spitting up and vomiting.

Infectious arthritis or Septic arthritis*typically causes extreme discomfort and difficulty using the affected joint. *The joint may be swollen, red and warm, and you might have a fever.

Infectious disease*Fever. *Diarrhea *Fatigue. *Muscle aches.

Inflammatory breast cancer*Rapid change in the appearance of one breast, over the course of several weeks.

*Thickness, heaviness or visible enlargement of one breast. *Discoloration, giving the breast a red, purple, pink or bruised appearance. *Unusual warmth of the affected breast. *Dimpling or ridges on the skin of the affected breast, similar to an orange peel. *Tenderness, pain or aching. *Enlarged lymph nodes under the arm, above the collarbone or below the collarbone. *Flattening or turning inward of the nipple.

Ingrown hair*Small, solid, rounded bumps (papules). *Small, pus-filled, blister-like lesions (pustules). *Skin darkening (hyperpigmentation). *Pain. *Itching. *Embedded hairs.

Ingrown toenail*Pain and tenderness in your toe along one or both sides of the nail. *Redness around your toenail. *Swelling of your toe around the nail. *Infection of the tissue around your toenail.

Inguinal hernia*A bulge in the area on either side of your pubic bone. *A burning, gurgling or aching sensation at the bulge. *Pain or discomfort in your groin, especially when bending over, coughing or lifting. *A heavy or dragging sensation in your groin. *Weakness or pressure in your groin. *Occasionally, pain and swelling around the testicles when the protruding intestine descends into the scrotum.

Insomnia*Difficulty falling asleep at night. *Awakening during the night. *Awakening too early. *Not feeling well rested after a night's sleep. *Daytime tiredness or sleepiness. *Irritability, depression or anxiety. *Difficulty paying attention, focusing on tasks or remembering. *Increased errors or accidents. *Tension headaches. *Distress in the stomach and intestines (gastrointestinal tract). *Ongoing worries about sleep.

Intermittent explosive disorder*Irritability. *Increased energy. *Rage.

*Racing thoughts. *Tingling. *Tremors. *Palpitations. *Chest tightness. *Feeling of pressure in the head.

Interstitial cystitis or painful bladder syndrome*Pain in your pelvis or between the vagina and anus in women or between the scrotum and anus in men (perineum). *Chronic pelvic pain. *A persistent, urgent need to urinate. *Frequent urination, often of small amounts, throughout the day and night. People with severe interstitial cystitis may urinate as often as 60 times a day. *Pain or discomfort while the bladder fills and relief after urinating. *Pain during sexual intercourse.

Interstitial lung disease*Dry cough. *Shortness of breath at rest or with exertion.

Intestinal ischemiaSymptoms of acute intestinal ischemia*Sudden abdominal pain that may range from mild to severe. *An urgent need to have a bowel movement. *Frequent, forceful bowel movements. *Tenderness or swelling in the abdomen. *Blood in your stool. *Nausea or vomiting or both. *Fever.

Symptoms of chronic intestinal ischemia: *Abdominal cramps or fullness, beginning within 30 minutes after eating and lasting one to three hours. *Abdominal pain that gets progressively worse over weeks or months. *Fear of eating because of subsequent pain. *Unintended weight loss. *Diarrhea. *Nausea or vomiting or both. *Bloating.

Intestinal lipodystrophy or Whipple's disease*Diarrhea. *Abdominal cramping and pain, which may worsen after meals. *Weight loss, associated with the malabsorption of nutrients. *Inflamed joints, particularly your ankles, knees and wrists. *Fatigue. *Weakness.

*Anemia. *Fever. *Cough. *Enlarged lymph nodes. *Skin darkening (hyperpigmentation) in areas exposed to the sun and in scars. *Chest pain. *Enlarged spleen.

Neurological signs and symptoms may include: *Difficulty walking. *Visual impairment, including lack of control of eye movements. *Seizures. *Confusion. *Memory loss.

Intestinal obstruction*Crampy abdominal pain that comes and goes. *Nausea. *Vomiting. *Diarrhea. *Constipation. *Inability to have a bowel movement or pass gas. *Swelling of the abdomen (distention).

Intracranial hematoma*Increasing headache. *Vomiting. *Drowsiness and progressive loss of consciousness. *Dizziness. *Confusion. *Unequal pupil size. *Slurred speech. *Increased blood pressure. *Lethargy. *Seizures. *Unconsciousness.

IntussusceptionSymptoms in children: *Stool mixed with blood and mucus (sometimes referred to as "currant jelly" stool because of its appearance). *Vomiting. *A lump in the abdomen. *Lethargy. *Diarrhea. *Fever. *Constipation.

Symptoms in adults: *Abdominal pain is the most common symptom, followed by nausea and vomiting and diarrhea.

Invasive lobular carcinoma*An area of thickening in part of the breast. *A new area of fullness or swelling in the breast. *A change in the texture or appearance of the skin over the breast, such as dimpling or thickening. *A newly inverted nipple.

Iritis or Uveitis*Eye redness. *Discomfort or achiness in the affected eye. *Sensitivity to light (photophobia). *Blurred vision. *Floating specks or spots in your vision.

Iron deficiency anemia*Extreme fatigue. *Pale skin. *Weakness. *Shortness of breath. *Chest pain. *Frequent infections *Headache. *Dizziness or lightheadedness. *Cold hands and feet. *Inflammation or soreness of your tongue. *Brittle nails. *Fast heartbeat. *Unusual cravings for non-nutritive substances, such as ice, dirt or starch. *Poor appetite, especially in infants and children with iron deficiency anemia. *An uncomfortable tingling or crawling feeling in your legs (restless legs syndrome).

Irritable bladder or overactive bladder*Feel a sudden urge to urinate that's difficult to control. *Experience urge incontinence — the involuntary loss of urine immediately following an urgent need to urinate. *Urinate frequently, usually eight or more times in 24 hours. *Awaken two or more times in the night to urinate (nocturia).

Irritable bowel syndrome*Abdominal pain or cramping. *A bloated feeling. *Gas. *Diarrhea or constipation — sometimes alternating bouts of constipation and diarrhea. *Mucus in the stool.

Ischemic colitis-

*Pain, tenderness or cramping in your belly, which can occur suddenly or gradually. *Bright red or maroon-colored blood in your stool or, at times, passage of blood alone without stool. *A feeling of urgency to move your bowels. *Diarrhea.

Itchy skin or Pruritus*Redness. *Bumps, spots or blisters. *Dry, cracked skin. *Leathery or scaly texture to the skin.

Jellyfish stings*Burning, prickling, stinging pain. *Red, brown or purplish tracks on the skin — a "print" of the tentacles' contact with your skin. *Itching. *Swelling. *Tingling and numbness. *Throbbing pain that radiates up a leg or an arm.

Signs and symptoms of severe jellyfish stings include: *Nausea and vomiting. *Headache. *Muscle and joint problems. *Weakness and dizziness. *Fever. *Loss of consciousness. *Difficulty breathing. *Heart problems.

Jet lag*Disturbed sleep — such as insomnia, early waking or excessive sleepiness. *Daytime fatigue. *Difficulty concentrating or functioning at your usual level. *Stomach problems, constipation or diarrhea. *A general feeling of not being well. *Muscle soreness. *Menstrual symptoms in women.

Jock itch*Usually begins with a reddened area of skin that spreads out from the crease in the groin in a half-moon shape onto the upper thigh. *The border of the rash may consist of a line of small, raised blisters. *The rash often itches or burns, and the skin may be flaky or scaly.

Joint sprain or Sprain and strainsSprains: *Pain. *Swelling.

*Bruising. *Limited ability to move the affected joint. *At the time of injury, you may hear or feel a "pop" in your joint.

Strains: *Pain. *Swelling. *Muscle spasms. *Limited ability to move the affected muscle.

Jumper's knee or patellar tendinitisThe pain in your knee may: *At first be present only as you begin physical activity or just after an intense workout. *Worsen until it interferes with playing your sport. *Eventually interfere with daily movements such as climbing stairs or rising from a chair.

Juvenile fibromyalgia or fibromyalgia*Widespread diffuse pain. *Head ache. *Sleep disturbances. *Fatigue. *pain or cramping in the lower abdomen. *depression and anxiety.

Juvenile rheumatoid arthritis or juvenile idiopathic arthritis*Pain. *Joint swelling. *Stiffness.

Kawasaki disease or mucocutaneous lymph node syndromeFirst phase: *Fever which often is higher than 102.2 F (39 C) and lasts more than five days. *Extremely red eyes (conjunctivitis) without a thick discharge. *A rash on the main part of the body (trunk) and in the genital area. *Red, dry, cracked lips and an extremely red, swollen tongue (strawberry tongue). *Swollen, red skin on the palms of the hands and the soles of the feet. *Swollen lymph nodes in the neck and perhaps elsewhere. *Irritability.

Second phase: *Peeling of the skin on the hands and feet, especially the tips of the fingers and toes, often in large sheets. *Joint pain. *Diarrhea. *Vomiting. *Abdominal pain. keratitis*Eye redness. *Eye pain.

*Excess tears or other discharge from your eye. *Difficulty opening your eyelid because of pain or irritation. *Blurred vision. *Decreased vision. *Sensitivity to light (photophobia) A feeling that something is in your eye. keratoconus*Blurred or distorted vision. *Increased sensitivity to bright light and glare. *Problems with night vision. *Many changes in eyeglass prescriptions. *Sudden worsening or clouding of vision, caused by a condition in which the back of your cornea ruptures and fills with fluid (hydrops).

Keratosis pilaris(KP)*Small white or red bumps, typically on the upper arms, legs, buttocks or cheeks. *Dry, rough and sometimes itchy skin in the areas with bumps. *Worsening in winter, when humidity is low and skin tends to be drier. kidney cancer*Blood in your urine, which may appear pink, red or cola colored. *Back pain just below the ribs that doesn't go away. *Weight loss. *Fatigue. *Intermittent fever. kidney cyst*Dull pain in your back or side *Fever. *Upper abdominal pain.

Kidney infection (pyelonephritis)*Fever. *Back, side (flank) or groin pain. *Abdominal pain. *Frequent urination. *Strong, persistent urge to urinate. *Burning sensation or pain when urinating. *Pus or blood in your urine (hematuria). *Urine that smells bad or is cloudy.

Kidney stones or renal lithiasis or nephrolithiasis*Severe pain in the side and back, below the ribs. *Pain that spreads to the lower abdomen and groin. *Pain that comes in waves and fluctuates in intensity. *Pain on urination. *Pink, red or brown urine. *Cloudy or foul-smelling urine.

*Nausea and vomiting. *Persistent need to urinate. *Urinating more often than usual. *Fever and chills if an infection is present. *Urinating small amounts of urine.

Kissing disease or mononucleosis*Fatigue. *General feeling of unwellness (malaise). *Sore throat, perhaps a strep throat that doesn't get better with antibiotic use. *Fever. *Swollen lymph nodes in your neck and armpits. *Swollen tonsils. *Headache. *Skin rash. *Soft, swollen spleen.

Klinefelter syndromeBabies: *Weak muscles. *Slow motor development — taking longer than average to sit up, crawl and walk. *Delay in speaking. *Quiet, docile personality. *Problems at birth, such as testicles that haven't descended into the scrotum.

Boys and teenagers: *Taller than average stature. *Longer legs, shorter torso and broader hips compared with other boys. *Absent, delayed or incomplete puberty. *After puberty, less muscular bodies and less facial and body hair compared with other teens. *Small, firm testicles. *Small penis. *Enlarged breast tissue (gynecomastia). *Weak bones. *Low energy levels. *Shyness. *Difficulty expressing feelings or socializing. *Problems with reading, writing, spelling or math. *Attention problems.

Men: *Infertility. *Small testicles and penis. *Taller than average stature. *Weak bones. *Decreased facial and body hair. *Enlarged breast tissue.

*Decreased sex drive. knee pain*Swelling and stiffness. *Redness and warmth to the touch. *Weakness or instability. *Popping or crunching noises. *Inability to fully straighten the knee. kyphosis*back pain and stiffness. *abnormally curved spine.

Lactase deficiency or lactose intolerance*Diarrhea. *Nausea, and sometimes, vomiting. *Abdominal cramps. *Bloating. *Gas. Lactation mastitis or mastitis*Breast tenderness or warmth to the touch. *Generally feeling ill (malaise). *Breast swelling. *Pain or a burning sensation continuously or while breast-feeding. *Skin redness, often in a wedge-shaped pattern. *Fever of 101 F (38.3 C) or greater.

Latex allergyMild symptoms: *Itching. *Skin redness. *Hives or rash.

More-severe symptoms: *Sneezing. *Runny nose. *Itchy, watery eyes. *Scratchy throat. *Difficulty breathing. *Wheezing. *Cough.

Lead poisoningLead poisoning symptoms in children: *Developmental delay. *Learning difficulties. *Irritability. *Loss of appetite. *Weight loss.

*Sluggishness and fatigue. *Abdominal pain. *Vomiting. *Constipation. *Hearing loss.

Lead poisoning symptoms in newborns: *Learning difficulties. *Slowed growth.

Lead poisoning symptoms in adults: *High blood pressure. *Abdominal pain. *Constipation. *Joint pains. *Muscle pain. *Declines in mental functioning. *Pain, numbness or tingling of the extremities. *Headache. *Memory loss. *Mood disorders. *Reduced sperm count, abnormal sperm. *Miscarriage or premature birth in pregnant women. left ventricular hypertrophy*Shortness of breath. *Fatigue. *Chest pain, often after exercising. *Sensation of rapid, fluttering or pounding heartbeats (palpitations). *Dizziness or fainting.

Legg-Calve-Perthes disease*Limping. *Pain or stiffness in the hip, groin, thigh or knee. *Limited range of motion of the hip joint.

Legionnaires' disease or Legionellosis*Headache. *Muscle pain. *Chills. *Fever that may be 104 F (40 C) or higher. *Cough, which may bring up mucus and sometimes blood. *Shortness of breath. *Chest pain. *Gastrointestinal symptoms, such as nausea, vomiting and diarrhea. *Confusion or other mental changes. leiomyomas or myomas or uterine fibroids*Heavy menstrual bleeding.

*Prolonged menstrual periods — seven days or more of menstrual bleeding. *Pelvic pressure or pain. *Frequent urination. *Difficulty emptying your bladder. *Constipation. *Backache or leg pains. leukemia*Fever or chills. *Persistent fatigue, weakness. *Frequent or severe infections. *Losing weight without trying. *Swollen lymph nodes, enlarged liver or spleen. *Easy bleeding or bruising. *Recurrent nosebleeds. *Tiny red spots in your skin (petechiae). *Excessive sweating, especially at night. *Bone pain or tenderness.

Leukoplakia*White or grayish in patches that can't be wiped away. *Irregular or flat-textured. *Thickened or hardened in areas. *Along with raised, red lesions (erythroplakia), which are more likely to show precancerous changes.

Lewy body dementia*Visual hallucinations. *Movement disorders. *Poor regulations of body function. *Cognitive problems. *Sleep difficulties. *Fluctuating attention. *Depression. lice*Intense itching. *Tickling feeling from movement of hair. *Lice on your scalp, body, clothing, or pubic or other body hair. Adult lice may be about the size of a sesame seed or slightly larger.

Lice eggs (nits) on hair shafts. Nits resemble tiny pussy willow buds. Nits can be mistaken for dandruff, but unlike dandruff, they can't be easily brushed out of hair. *Small red bumps on the scalp, neck and shoulders.

Lichen nitidus*Size. The bumps range in size from pinpoint to pinhead size. *Shape. They are flat topped and round. *Color. Bumps are usually the same color as your skin. They may be slightly pink on people with

lighter skin, or lighter than normal skin color on people with darker skin. *Location: bumps commonly occur on the chest, abdomen, arms and genital areas, including the penis. They rarely occur on the palms, soles of the feet, mucous membranes or fingernails. *Itch: crease or constant pressure on the skin, such as a fold of skin on the abdomen or the crease of skin on the inside of the elbow or wrist. lichen planus*Purplish, flat-topped bumps, most often on the inner forearm, wrist or ankle, but sometimes on the external genitals. *Itching. *Blisters that may break to form scabs or crusts. *White spots or patches in the mouth — inside the cheeks or on the gums, lips or tongue. *Painful oral or vaginal ulcers. *Hair loss and scalp discoloration. *Nail damage or loss. lichen sclerosus*Itching (pruritus), which can be severe. *Discomfort, which is generally greater if lichen sclerosus appears on or around your genital or anal areas. *Smooth white spots on your skin that may grow into blotchy, wrinkled patches. *Easy bruising or tearing. *In severe cases, bleeding, blistering or ulcerated lesions. *Painful intercourse.

Lichen simplex chronicus or neurodermatitis*Itchy skin in a single limited area. *Leathery or scaly texture to the skin. *Raised, rough patch that is red or darker than the rest of your skin.

Limited scleroderma, or CREST syndrome*Tight, hardened skin. In limited scleroderma, skin changes typically affect only the lower arms and legs, including fingers and toes, and sometimes the face and neck. Skin can look shiny from being pulled taut over underlying bone. It may become difficult to bend your fingers or to open your mouth. *Raynaud's phenomenon.skin turns white before becoming blue, cold and numb. *Red spots or lines on skin. *Bumps under the skin. *Swallowing difficulties.

Lipomas*Situated just under your skin. They commonly occur in the neck, shoulders, back, abdomen, arms and thighs. *Soft and doughy to the touch. They also move easily with slight finger pressure. *Generally small. Lipomas are typically less than 2 inches (5 centimeters) in diameter, but they can grow. *Sometimes painful. Lipomas can be painful if they grow and press on nearby nerves or if they contain many blood vessels.

Listeria infection or Listeriosis*Fever. *Muscle aches. *Nausea. *Diarrhea.

If the listeria infection spreads to your nervous system, signs and symptoms may include: *Headache. *Stiff neck. *Confusion or changes in alertness. *Loss of balance. *Convulsions.

Liver disease*Skin and eyes that appear yellowish (jaundice). *Abdominal pain and swelling. *Swelling in the legs and ankles. *Itchy skin. *Dark urine color. *Pale stool color, or bloody or tar-colored stool. *Chronic fatigue. *Nausea or vomiting. *Loss of appetite. *Tendency to bruise easily.

Lock jaw or tetanus*Spasms and stiffness in your jaw muscles. *Stiffness of your neck muscles. *Difficulty swallowing. *Stiffness of your abdominal muscles. *Painful body spasms lasting for several minutes, typically triggered by minor occurrences, such as a draft, loud noise, physical touch or light. *Fever. *Sweating. *Elevated blood pressure.

Long QT syndrome (LQTS)*Fainting(syncope). *Seizures. *Sudden death.

Low sperm count*Problems with sexual function — for example, low sex drive or difficulty maintaining an erection (erectile dysfunction). *Pain, swelling or a lump in the testicle area. *Decreased facial or body hair or other signs of a chromosome or hormone abnormality.

Lung cancer*A new cough that doesn't go away.

*Changes in a chronic cough or "smoker's cough". *Coughing up blood, even a small amount. *Shortness of breath. *Chest pain. *Wheezing. *Hoarseness. *Losing weight without trying. *Bone pain. *Headache.

Lung collapse or Pneumothorax*Include sudden chest pain and shortness of breath.

Lupus*Fatigue and fever. *Joint pain, stiffness and swelling. *Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose. *Skin lesions that appear or worsen with sun exposure (photosensitivity). *Fingers and toes that turn white or blue when exposed to cold or during stressful periods (Raynaud's phenomenon). *Shortness of breath. *Chest pain. *Dry eyes. *Headaches, confusion and memory loss.

Lyme diseaseEarly signs and symptoms: *Rash. *Flu like symptoms.

Later signs and symptoms: *Joint pain. *Neurological disease.

Less common signs and symptoms: *Heart problems, such as an irregular heartbeat. Heart problems rarely last more than a few days or weeks. *Eye inflammation. *Liver inflammation (hepatitis). *Severe fatigue.

Lymphedema*Swelling of part or all of your arm or leg, including fingers or toes. *A feeling of heaviness or tightness. *Restricted range of motion. *Aching or discomfort. *Recurring infections. *Hardening and thickening of the skin (fibrosis).

Lymphocytic colitis or microscopic colitis-

*Chronic watery diarrhea. *Abdominal pain or cramps. *Weight loss. *Nausea. *Fecal incontinence.

Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC)*Colon cancer that occurs at a younger age, especially before age 50. *A family history of colon cancer that occurs at a young age. *A family history of cancer that affects the uterus (endometrial cancer). *A family history of other related cancers, including ovarian cancer, kidney cancer, stomach cancer, small intestine cancer, liver cancer, sweat gland cancer (sebaceous carcinoma) and other cancers.

Lymphandenitis or Swollen lymph nodes*Tender and painful lymph nodes. *Swollen lymph nodes that may be the size of a pea or kidney bean, or even larger. *Runny nose, sore throat, fever and other indications of an upper respiratory infection. *General swelling of lymph nodes throughout your body — which may indicate an infection, such as HIV or mononucleosis, or an immune disorder, such as lupus or rheumatoid arthritis. *Swollen limb, possibly indicating lymph system blockage caused by swelling in a lymph node too far under your skin to feel. *Hardened, fixed, rapidly growing nodes, indicating a possible tumor. *Fever. *Night sweats.

Macular degeneration(dry)*The need for brighter light when reading or doing close work. *Increasing difficulty adapting to low light levels, such as when entering a dimly lit restaurant. *Increasing blurriness of printed words. *A decrease in the intensity or brightness of colors. *Difficulty recognizing faces. *A gradual increase in the haziness of your central or overall vision. *Crooked central vision. *A blurred or blind spot in the center of your field of vision. *Hallucinations of geometric shapes or people, in case of advanced macular degeneration.

Macular degeneration(wet)*Visual distortions, such as straight lines appearing wavy or crooked, a doorway or street sign looking lopsided, or objects appearing smaller or farther away than they really are. *Decreased central vision. *Decreased intensity or brightness of colors. *Well-defined blurry spot or blind spot in your field of vision. *Abrupt onset.

*Rapid worsening. *Hallucinations of geometric shapes, animals or people, in cases of advanced macular degeneration.

Malaria*Moderate to severe shaking chills. *High fever. *Profuse sweating as body temperature falls. *Headache. *Vomiting. *Diarrhea.

Male breast cancer*A painless lump or thickening in your breast tissue. *Changes to the skin covering your breast, such as dimpling, puckering, redness or scaling. *Changes to your nipple, such as redness or scaling, or a nipple that begins to turn inward. *Discharge from your nipple.

Male hypogonadismFetal development: *Female genitals. *Ambiguous genitals — genitals that are neither clearly male nor clearly female. *Underdeveloped male genitals.

Puberty: *Decreased development of muscle mass. *Lack of deepening of the voice. *Impaired growth of body hair. *Impaired growth of the penis and testicles. *Excessive growth of the arms and legs in relation to the trunk of the body. *Development of breast tissue (gynecomastia).

Adulthood: *Erectile dysfunction. *Infertility. *Decrease in beard and body hair growth. *Decrease in muscle mass *Development of breast tissue (gynecomastia). *Loss of bone mass (osteoporosis). *Fatigue. *Decreased sex drive. *Difficulty concentrating. *Hot flashes.

Male infertility*The inability to conceive a child Problems with sexual function — for example, difficulty with ejaculation, reduced sexual desire or difficulty maintaining an erection (erectile dysfunction). *Pain, swelling or a lump in the testicle area.

*Recurrent respiratory infections. *Decreased facial or body hair or other signs of a chromosomal or hormonal abnormality. *Having a lower than normal sperm count (fewer than 15 million sperm per milliliter of semen or a total sperm count of less than 39 million per ejaculate).

Mammary duct ectasia*A dirty white, greenish or black nipple discharge from one or both nipples. *Tenderness in the nipple or surrounding breast tissue. *Redness of the nipple and sometimes the surrounding area. *A breast lump or thickening near the clogged duct. *A nipple that's turned inward (inverted).

Marfan syndrome*Tall and slender build. *Disproportionately long arms, legs, fingers and toes. *A breastbone that protrudes outward or dips inward. *A high, arched palate and crowded teeth. *Heart murmurs. *Extreme nearsightedness. *An abnormally curved spine. *Flat feet.

Measles*Fever. *Dry cough. *Runny nose. *Sore throat. *Inflamed eyes (conjunctivitis). *Tiny white spots with bluish-white centers on a red background found inside the mouth on the inner lining of the cheek — also called Koplik's spots. *A skin rash made up of large, flat blotches that often flow into one another.

Melanoma*A change in an existing mole. *The development of a new pigmented or unusual-looking growth on your skin.

Membranous nephropathy*Swelling in the legs and ankles. *Weight gain. *Fatigue. *Poor appetite. *Frothy urine. *Elevated fat levels in the blood (hyperlipidemia). *Increased protein levels in the urine (proteinuria). *Decreased protein levels in the blood, particularly of the protein albumin.

Meniere's disease*Recurring episodes of vertigo. spin around quickly several times and suddenly stop. *Hearing loss.

*Ringing in the ear (tinnitus). *Feeling of fullness in the ear.

Meningioma*Changes in vision, such as seeing double or blurriness. *Headaches that worsen with time. *Hearing loss. *Memory loss. *Loss of smell. *Seizures. *Weakness in your arms or legs.

Meningitis*Sudden high fever. *Severe headache that isn't easily confused with other types of headache. *Stiff neck. *Vomiting or nausea with headache. *Confusion or difficulty concentrating. *Seizures. *Sleepiness or difficulty waking up. *Sensitivity to light. *Lack of interest in drinking and eating. *Skin rash in some cases, such as in meningococcal meningitis.

Meniscus tear or Torn meniscus*A popping sensation. *Swelling or stiffness. *Pain, especially when twisting or rotating your knee. *Difficulty straightening your knee fully. *Experiencing what feels like a block to moving your knee, as if your knee were locked in place.

Menopause*Irregular periods. *Vaginal dryness. *Hot flashes. *Night sweats. *Sleep problems. *Mood changes. *Weight gain and slowed. *metabolism. *Thinning hair and dry skin. *Loss of breast fullness.

Mental illness*Feeling sad or down. *Confused thinking or reduced ability to concentrate. *Excessive fears or worries, or extreme feelings of guilt. *Extreme mood changes of highs and lows. *Withdrawal from friends and activities.

*Significant tiredness, low energy or problems sleeping. *Detachment from reality (delusions), paranoia or hallucinations. *Inability to cope with daily problems or stress. *Trouble understanding and relating to situations and to people. *Alcohol or drug abuse. *Major changes in eating habits. *Sex drive changes. *Excessive anger, hostility or violence. *Suicidal thinking.

Meralgia paresthetica*Tingling and numbness in the outer (lateral) part of your thigh. *Burning pain in or on the surface of the outer part of your thigh.

Merkel cell carcinoma*fast-growing, painless nodule (tumor) on your skin. *The nodule may be skin colored or may appear in shades of red, blue or purple. *Most Merkel cell carcinomas appear on the face, head or neck.

Mesentric lymphadenitis*Abdominal pain, often centered on the lower, right side, but the pain can sometimes be more widespread. *General abdominal tenderness. *Fever. *Diarrhea. *Nausea and vomiting. *General feeling of being unwell (malaise).

MesotheliomaPleural mesothelioma*Chest pain under the rib cage. *Painful coughing. *Shortness of breath. *Unusual lumps of tissue under the skin on your chest. *Unexplained weight loss.

Peritoneal mesothelioma: *Abdominal pain. *Abdominal swelling. *Lumps of tissue in the abdomen. *Unexplained weight loss.

Metatarsalgia*Sharp, aching or burning pain in the ball of your foot — the part of the sole just behind your toes. *Pain that worsens when you stand, run, flex your feet or walk — especially barefoot on a hard surface — and improves when you rest. *Sharp or shooting pain, numbness, or tingling in your toes. *A feeling of having a pebble in your shoe.

Methicillin-resistant Staphylococcus aureus (MRSA) infection*small red bumps that resemble pimples, boils or spider bites. *These can quickly turn into deep, painful abscesses.

Monoclonal gammopathy of undetermined significance (MGUS)*Nerve problems. *Tingling & numbness.

Microcephaly*A head size significantly smaller than that of other children of the same age and sex.

Microvascular disease or Small vessel disease*Chest pain, squeezing or discomfort. *Chest pain associated with discomfort in your left arm or jaw. *Chest pain that worsens with daily activities and at times of emotional stress. *Neck, shoulder, upper back or abdominal discomfort. *Shortness of breath. *Unusual fatigue. *A loss of energy. *Trouble sleeping.

MigraineProdrome: *Constipation. *Depression. *Food cravings. *Hyperactivity. *Irritability. *Neck stiffness. *Uncontrollable yawning.

Aura: *Visual phenomena, such as seeing various shapes, bright spots or flashes of light. *Vision loss. *Pins and needles sensations in an arm or leg. *Speech or language problems (aphasia).

Aphasia: *Pain on one side or both sides of your head. *Pain that has a pulsating, throbbing quality. *Sensitivity to light, sounds and sometimes smells. *Nausea and vomiting. *Blurred vision. *Lightheadedness, sometimes followed by fainting.

Postdrome: *During this time you may feel drained and washed out, though some people report feeling mildly euphoric.

Migraine with auraVisual signs and symptoms:

*Blind spots (scotomas), which are sometimes outlined by simple geometric designs. *Zigzag lines that gradually float across your field of vision. *Shimmering spots or stars. *Changes in vision. *Flashes of light.

Other sensory disturbances: *Feelings of numbness, typically felt as tingling in one hand or in your face. *Difficulty with speech or language. *Muscle weakness.

Mild cognitive impairment(MCI)*You forget things more often. *You forget important events such as appointments or social engagements. *You lose your train of thought or the thread of conversations, books or movies. *You feel increasingly overwhelmed by making decisions, planning steps to accomplish a task or interpreting instructions. *You start to have trouble finding your way around familiar environments. *You become more impulsive or show increasingly poor judgment. *Depression. *Irritability and aggression. *Anxiety. *Apathy.

Milia*Tiny white bumps on baby's nose, chin or cheeks, though they may also occur in other areas, such as on the upper trunk and limbs.

Milk allergy*Hives. *Wheezing. *Vomiting. *Loose stools, which may contain blood. *Diarrhea. *Abdominal cramps. *Coughing or wheezing. *Runny nose. *Watery eyes. *Itchy skin rash, often around the mouth. *Colic, in babies.

Miscarriage*Vaginal spotting or bleeding. *Pain or cramping in your abdomen or lower back. *Fluid or tissue passing from your vagina.

Mitral valve stenosis*Shortness of breath, especially with exertion or when you lie down. *Fatigue, especially during increased physical activity.

*Swollen feet or legs. *Heart palpitations — sensations of a rapid, fluttering heartbeat. *Dizziness or fainting. *Heavy coughing, sometimes with blood-tinged sputum. *Chest discomfort or chest pain. *Severe headache, trouble speaking or other symptoms of stroke.

MittelschmerzPain may be: *On one side of your lower abdomen. *Dull and cramp-like. *Sharp and sudden. *Accompanied by mild vaginal bleeding or discharge. *Rarely, severe.

Mixed cinnective tissue disease*General feeling of being unwell. *fatigue and a mild fever. *Cold and numb fingers or toes (Raynaud's phenomenon). *Swollen fingers or hands. *Muscle and joint pain. . *Rash. Red or reddish brown patches may appear over the knuckles.

Molar pregnancy or Hydatidiform mole*Dark brown to bright red vaginal bleeding during the first trimester. *Severe nausea and vomiting. *Sometimes vaginal passage of grape-like cysts. *Rarely pelvic pressure or pain.

Mold allergy*Sneezing. *Runny or stuffy nose. *Cough and postnasal drip. *Itchy eyes, nose and throat. *Watery eyes.

Moles*can be brown, tan, black, red, blue or pink. They can be smooth, wrinkled, flat or raised. . *Shape. They can vary in shape from oval to round. *Size. Moles are usually less than 1/4 inch (about 6 millimeters) in diameter.

Molluscum contagiosumBumps: *Are raised, round and flesh colored. *Are small — typically under about 1/4 inch (smaller than 6 millimeters) in diameter. *Characteristically have a small indentation (umbilication) or dot at the top near the center. *Can become red and inflamed May be itchy. *Can be easily removed by scratching or rubbing, which can spread the virus to adjacent skin. *Usually appear on the face, neck, armpits, arms and tops of the hands in children.

*May be seen on the genitals, lower abdomen and inner upper thighs in adults if the infection was sexually transmitted.

Morning sickness*Nausea with or without vomiting.

Morphea*Hardening and thickening of the skin. *Discoloration of the affected skin to look lighter or darker than the surrounding area. *Oval-shaped patches that may change colors and gradually develop a whitish center. *Linear patches, especially when on arms and legs. *Loss of hair and sweat glands in the affected area over time.

Morton's neuroma*A feeling as if you're standing on a pebble in your shoe. *A burning pain in the ball of your foot that may radiate into your toes. *Tingling or numbness in your toes.

Mosquito bites*A puffy, white bump that appears a few minutes after the bite. *A hard, itchy, reddish-brown bump, or multiple bumps, appearing a day or so after the bite or bites. *Swelling around bites. *Small blisters instead of hard bumps. *Dark spots that look like bruises. *A large area of swelling and redness. *Low-grade fever. *Hives. *Swollen lymph nodes.

Mouth cancer*A sore that doesn't heal. *A lump or thickening of the skin or lining of your mouth. *A white or reddish patch on the inside of your mouth. *Loose teeth. *Poorly fitting dentures. *Tongue pain. *Jaw pain or stiffness. *Difficult or painful chewing. *Difficult or painful swallowing. *Sore throat. *Feeling that something is caught in your throat.

Multiple sclerosis(MS)*Numbness or weakness in one or more limbs that typically occurs on one side of your body at a time, or the legs and trunk. *Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement. *Double vision or blurring of vision.

*Tingling or pain in parts of your body. *Electric-shock sensations that occur with certain neck movements, especially bending the neck forward. *Tremor, lack of coordination or unsteady gait. *Slurred speech. *Fatigue. *Dizziness. *Problems with bowel and bladder function.

Multiple system atrophy (MSA) or Shy-Drager syndromeParkinsonian type: *Rigid muscles and difficulty bending your arms and legs. *Slow movement (bradykinesia). *Tremors (rare in MSA compared with classic Parkinson's disease). *Impaired posture and balance.

Cerebellar type: *Impairment of movement and coordination, such as unsteady gait and loss of balance. *Slurred, slow or low-volume speech (dysarthria). *Visual disturbances, such as blurred or double vision and difficulty focusing your eyes. *Difficulty swallowing (dysphagia) or chewing.

General signs and symptoms: *Postural (orthostatic) hypotension, a form of low blood pressure that makes you feel dizzy or lightheaded, or even faint, when you stand up from sitting or lying down. *You also can develop dangerously high blood pressure levels while lying down.

Urinary and bowel dysfunction: *Constipation. *Loss of bladder or bowel control (incontinence).

Sweating abnormalities: *A reduction in the production of perspiration, tears and saliva Impaired control of body temperature, often causing cold hands or feet as well as heat intolerance due to impaired sweating.

Sleep disorders: *Agitated sleep due to "acting out" one's dreams. *Abnormal breathing at night.

Sexual dysfunction: *Inability to achieve or maintain an erection (impotence). *Loss of libido.

Cardiovascular problems: *Irregular heartbeat.

Psychiatric problems: *Difficulty controlling emotions.

Multiple endocrine neoplasia, type 1 (MEN 1) or Wermer's syndrome*Tiredness, bone pain, fractures and kidney stones, as well as stomach or intestinal ulcers.

Multiple myeloma-

*Bone pain, especially in your spine or chest. *Nausea. *Constipation. *Loss of appetite. *Mental fogginess or confusion. *Fatigue. *Frequent infections. *Weight loss. *Weakness or numbness in your legs. *Excessive thirst.

Mumps*Swollen, painful salivary glands on one or both sides of your face (parotitis). *Fever. *Headache. *Weakness and fatigue. *Loss of appetite. *Pain while chewing or swallowing.

Muscle cramps*Particularly muscles in the calf undergo cramps. *In addition to the sudden, sharp pain, you may also be able to feel or see a hard lump of muscle tissue beneath your skin.

Muscular dystrophyDuchenne muscular dystrophy: *Frequent falls. *Difficulty getting up from a lying or sitting position. *Trouble running and jumping. *Waddling gait. *Walking on the toes. *Large calf muscles. *Muscle pain and stiffness. *Learning disabilities.

Becker muscular dystrophy: Signs and symptoms are similar to those of Duchenne muscular dystrophy.

Myasthenia gravisEye muscles: *Drooping of one or both eyelids (ptosis). *Double vision (diplopia), which may be horizontal or vertical, and improves or resolves when one eye is closed.

Face and throat muscles: *Altered speaking. Your speech may sound very soft or nasal, depending upon which muscles have been affected. *Difficulty swallowing. You may choke very easily, which makes it difficult to eat, drink or take pills. In some cases, liquids you're trying to swallow may come out your nose.

*Problems chewing. The muscles used for chewing may wear out halfway through a meal, particularly if you've been eating something hard to chew, such as steak. *Limited facial expressions. Your family members may comment that you've "lost your smile" if the muscles that control your facial expressions have been affected.

Neck and limb muscles: *Weakness in your neck, arms and legs, but this usually happens along with muscle weakness in other parts of your body, such as your eyes, face or throat.

Myelodysplastic syndromes*Fatigue. *Shortness of breath. *Unusual paleness (pallor) due to anemia. *Easy or unusual bruising or bleeding. *Pinpoint-sized red spots just beneath your skin caused by bleeding (petechiae). *Frequent infections.

Myelofibrosis*Feeling tired, weak or short of breath, usually because of anemia Pain or fullness below your ribs on the left side, due to an enlarged spleen. *Pale skin. *Easy bruising. *Easy bleeding *Excessive sweating during sleep (night sweats). *Fever. *Frequent infections. *Bone pain.

Myelomeningocele or Spina bifidaspina bifida occulta: *An abnormal tuft of hair. *A collection of fat. *A small dimple or birthmark. *Muscle weakness of the legs, sometimes involving paralysis. *Bowel and bladder problems. *Seizures, especially if the child requires a shunt. *Orthopedic problems — such as deformed feet, uneven hips and a curved spine (scoliosis).

Myocarditis*Chest pain. *A rapid or abnormal heartbeat (arrhythmia). *Shortness of breath, at rest or during physical activity. *Fluid retention with swelling of your legs, ankles and feet. *Fatigue. *Other signs and symptoms you'd have with a viral infection, such as a headache, body aches, joint pain, fever, a sore throat or diarrhea.

Myocarditis in children: *Fever.

*Fainting. *Breathing difficulties. *Rapid breathing. *Bluish or grayish discoloration of the skin.

Myoclonusjerks, shakes or spasms that are: *Sudden. *Brief. *Involuntary. *Shock-like. *Variable in intensity and frequency. *Localized to one part of the body or all over the body. *Sometimes severe enough to interfere with eating, speaking or walking.

Myofascial pain syndrome*Deep, aching pain in a muscle. *Pain that persists or worsens. *A tender knot in a muscle. *Difficulty sleeping due to pain.

Myopia or Nearsightedness*Blurry vision when looking at distant objects. *The need to squint or partially close the eyelids to see clearly. *Headaches caused by eyestrain. *Difficulty seeing while driving a vehicle, especially at night (night myopia). *Persistently squint. *Need to sit closer to the television, movie screen or the front of the classroom. *Seem to be unaware of distant objects. *Blink excessively. *Rub his or her eyes frequently.

Naegleria infection*A change in the sense of smell or taste. *Fever. *Sudden headache. *Stiff neck. *Sensitivity to light. *Nausea and vomiting. *Confusion. *Loss of balance. *Sleepiness. *Seizures. *Hallucinations.

Nail fungus or onychomycosis*Thickened. *Brittle, crumbly or ragged.

*Distorted in shape. *Dull, with no shine. *A dark color, caused by debris building up under your nail.

Narcissistic personality disorder*Having an exaggerated sense of self-importance. *Expecting to be recognized as superior even without achievements that warrant it. *Exaggerating your achievements and talents. *Being preoccupied with fantasies about success, power, brilliance, beauty or the perfect mate. *Believing that you are superior and can only be understood by or associate with equally special people. *Requiring constant admiration. *Having a sense of entitlement. *Expecting special favors and unquestioning compliance with your expectations. *Taking advantage of others to get what you want. *Having an inability or unwillingness to recognize the needs and feelings of others. *Being envious of others and believing others envy you. *Behaving in an arrogant or haughty manner.

Nasal polyps*A runny nose. *Persistent stuffiness. *Postnasal drip. *Decreased or absent sense of smell. *Loss of sense of taste. *Facial pain or headache. *Pain in your upper teeth. *A sense of pressure over your forehead and face. *Snoring. *Itching around your eyes.

Nasopharyngeal carcinoma*A lump in your neck caused by a swollen lymph node. *Blood in your saliva. *Bloody discharge from your nose. *Nasal congestion. *Hearing loss. *Frequent ear infections. *Headaches.

Nephroblastoma or Wilms' tumor*Abdominal swelling. *An abdominal mass you can feel Abdominal pain. *Fever. *Blood in the urine.

Nephrotic syndrome-

*Severe swelling (edema), particularly around your eyes and in your ankles and feet. *Foamy urine, which may be caused by excess protein in your urine. *Weight gain due to excess fluid retention.

NeuroblastomaNeuroblastoma in the abdomen: *Abdominal pain. *A mass under the skin that isn't tender when touched. *Changes in bowel habits, such as diarrhea. *Swelling in the legs.

Neuroblastoma in the chest: *Wheezing. *Chest pain. *Changes to the eyes, including drooping eyelids and unequal pupil size.

Other signs and symptoms that may indicate neuroblastoma include: *Lumps of tissue under the skin. *Eyeballs that seem to protrude from the sockets (proptosis). *Dark circles, similar to bruises, around the eyes. *Back pain. *Fever. *Unexplained weight loss. *Bone pain.

Neurodermatitis*Itchy skin in a single limited area. *Leathery or scaly texture to the skin. *Raised, rough patch that is red or darker than the rest of your skin.

NeurofibromatisisNeurofibromatosis 1 (NF1): *Flat, light brown spots on the skin. *Freckling in the armpits or groin area. *Soft bumps on or under the skin (neurofibromas). *Tiny bumps on the iris of your eye (Lisch nodules). *Bone deformities. *learning disabilities. *Larger than average head size. *Short stature.

Neurofibromatosis 2 (NF2): *Gradual hearing loss. *Ringing in the ears. *Poor balance. *Facial drop. *Numbness and weakness in the arms or legs. *Pain. *Balance difficulties.

Nickel allergy*Rash or bumps on the skin. *Itching, which may be severe. *Redness or changes in skin color. *Dry patches of skin that may resemble a burn. *Blisters and draining fluid in severe cases.

Nicotine dependence or tobacco dependence*You can't stop smoking. *You experience withdrawal symptoms when you try to stop. *Your attempts at stopping have caused physical and mood-related signs and symptoms, such as strong cravings, anxiety, irritability, restlessness, difficulty concentrating, depressed mood, frustration, anger, increased hunger, insomnia, constipation or diarrhea. *You keep smoking despite health problems with your lungs or your heart. *You give up social or recreational activities in order to smoke.

Niemann-Pick disease*Progressive deterioration of the brain, nerves and organs.

Nightmare disorder*Your dream seems vivid and real, often becoming more disturbing as the dream unfolds. *Your dream storyline is usually related to threats to your safety or survival. *Your dream wakes you. *You feel scared, anxious, angry, sad or disgusted as a result of your dream. *You feel sweaty or have a pounding heartbeat, but do not leave the bed. *You can think clearly upon awakening and can recall details of your dream. *Your dream occurs near the end of your sleep time. *Your dream keeps you from falling back to sleep easily.

Non-Hodgkin's lymphoma*Painless, swollen lymph nodes in your neck, armpits or groin. *Abdominal pain or swelling. *Chest pain, coughing or trouble breathing. *Fatigue. *Fever. *Night sweats. *Weight loss.

Nonalcoholic fatty liver disease*Fatigue. *Pain in the upper right abdomen. *Weight loss.

Nonallergic rhinitis*Stuffy nose. *Runny nose. *Sneezing. *Mucus (phlegm) in the throat (postnasal drip).

Nonulcer stomach pain*A burning sensation or discomfort in your upper abdomen or lower chest, sometimes relieved by food or antacids. *Bloating. *Belching. *An early feeling of fullness when eating. *Nausea.

Norovirus infection*Nausea. *Vomiting. *Abdominal pain or cramps. *Watery or loose diarrhea. *Malaise. *Low-grade fever. *Muscle pain.

Obsessive-compulsive disorder (OCD)obsession symptoms: *Fear of being contaminated by shaking hands or by touching objects others have touched. *Doubts that you've locked the door or turned off the stove. *Intense stress when objects aren't orderly or facing a certain way. *Images of hurting yourself or someone else. *Thoughts about shouting obscenities or acting inappropriately. *Avoidance of situations that can trigger obsessions, such as shaking hands. *Distress about unpleasant sexual images repeating in your mind.

Compulsion symptoms: *Hand-washing until your skin becomes raw. *Checking doors repeatedly to make sure they're locked. *Checking the stove repeatedly to make sure it's off. *Counting in certain patterns. *Silently repeating a prayer, word or phrase. *Arranging your canned goods to face the same way.

Occupational ashthma*Wheezing, sometimes just at night. *Coughing. *Shortness of breath. *Chest tightness. *Runny nose. *Nasal congestion. *Eye irritation and tearing.

Ocular rosacea*Dry eyes. *Burning or stinging in the eyes. *Itchy eyes.

*Grittiness or feeling of having a foreign body in the eye or eyes. *Blurred vision. *Sensitivity to light (photophobia). *Redness. *Dilated small blood vessels on the white part of the eye that are visible when you look in a mirror. *Red, swollen eyelids. *Tearing.

Oppositional defiant disorder(ODD)Angry and irritable mood: *Often loses temper. *Is often touchy or easily annoyed by others. *Is often angry and resentful.

Argumentative and defiant behavior: *Often argues with adults or people in authority. *Often actively defies or refuses to comply with adults' requests or rules. *Often deliberately annoys people. *Often blames others for his or her mistakes or misbehavior.

Vindictiveness: *Is often spiteful or vindictive. *Has shown spiteful or vindictive behavior at least twice in the past six months.

Ovarian hyperstimulation syndrome(OHSS)Mild to moderate OHSS: *Mild to moderate abdominal pain that may come and go. *Abdominal bloating or increased waist size. *Nausea. *Vomiting. *Diarrhea. *Tenderness in the area of your ovaries.

Severe OHSS: *Rapid weight gain — such as 5 pounds (2.3 kilograms) in one day or 10 pounds (4.5 kilograms) in three days or more. *Severe abdominal pain. *Severe, persistent nausea and vomiting. *Decreased urination. *Dark urine. *Shortness of breath. *Tight or enlarged abdomen. *Dizziness.

Optic neuritis*eye pain that's worsened by eye movement. *Sometimes the pain feels like a dull ache behind the eye. *Vision loss.

*loss of color vision. *flashing lights.

Oral lichen planuslesions may appear as: *Lacy, white, raised patches of tissues. *Red, swollen, tender patches of tissues. *Open sores.

These lesions may appear on the: *Inside of the cheeks, the most common location. *Gums. *Tongue. *Inner tissues of the lips *Palate. *Pain or discomfort. *A burning sensation. *Change in taste or a blunted taste sensation if the tongue is affected. *Sensitivity to hot or spicy foods. *Bleeding and irritation with tooth brushing. *Inflammation of the gums (gingivitis).

Oral thrush or oral candidiasis*Creamy white lesions on your tongue, inner cheeks, and sometimes on the roof of your mouth, gums and tonsils. *Slightly raised lesions with a cottage cheese-like appearance. *Redness or soreness that may be severe enough to cause difficulty eating or swallowing. *Slight bleeding if the lesions are rubbed or scraped. *Cracking and redness at the corners of your mouth (especially in denture wearers). *A cottony feeling in your mouth *Loss of taste.

Infected breasts symptoms: *Unusually red, sensitive, cracked or itchy nipples. *Shiny or flaky skin on the darker, circular area around the nipple (areola). *Unusual pain during nursing or painful nipples between feedings. *Stabbing pains deep within the breast.

Orchitis*Swelling in one or both testicles. *Pain ranging from mild to severe. *Tenderness in one or both testicles, which may last for weeks. *Fever. *Nausea and vomiting.

Osgood-Schlatter disease*Pain while running & jumping. *Discomfort.

Osteoarthritis-

*Pain. Your joint may hurt during or after movement. *Tenderness. Your joint may feel tender when you apply light pressure to it. *Stiffness. Joint stiffness may be most noticeable when you wake up in the morning or after a period of inactivity. *Loss of flexibility. You may not be able to move your joint through its full range of motion. *Grating sensation. You may hear or feel a grating sensation when you use the joint. *Bone spurs. These extra bits of bone, which feel like hard lumps, may form around the affected joint.

Osteochondritis dissecans*Pain. The most common symptom of osteochondritis dissecans, pain may be triggered by physical activity — walking up stairs, climbing a hill or playing sports. *Joint popping or locking. Your joint may pop or get stuck in one position if a loose fragment gets caught between bones during movement. *Joint weakness. You may feel that your joint is "giving way" or weakening. *Decreased range of motion. You may be unable to straighten your leg or arm completely. *Swelling and tenderness. The skin around your joint may become swollen and tender.

Osteomalacia*Dull, aching pain associated with osteomalacia most commonly affects the lower back, pelvis, hips, legs and ribs. *Muscle weakness.

Osteomyelitis*Fever or chills. *Irritability or lethargy in young children. *Pain in the area of the infection. *Swelling, warmth and redness over the area of the infection.

Osteoporosis*Back pain, caused by a fractured or collapsed vertebra. *Loss of height over time. *A stooped posture. *A bone fracture that occurs much more easily than expected.

Ovarian cancer*Abdominal bloating or swelling. *Quickly feeling full when eating Weight loss. *Discomfort in the pelvis area. *Changes in bowel habits, such as constipation. *A frequent need to urinate.

Ovarian cysts*Pelvic pain — a dull ache that may radiate to your lower back and thighs. *Pelvic pain shortly before your period begins or just before it ends. *Pelvic pain during intercourse (dyspareunia). *Pain during bowel movements or pressure on your bowels. *Nausea, vomiting or breast tenderness like that experienced during pregnancy.

*Fullness or heaviness in your abdomen. *Pressure on your bladder that causes you to urinate more frequently or have difficulty emptying your bladder completely.

Peripheral artery disease(PAD)*Painful cramping in your hip, thigh or calf muscles after activity, such as walking or climbing stairs (intermittent claudication). *Leg numbness or weakness. *Coldness in your lower leg or foot, especially when compared with the other side. *Sores on your toes, feet or legs that won't heal. *A change in the color of your legs. *Hair loss or slower hair growth on your feet and legs. *Slower growth of your toenails. *Shiny skin on your legs. *No pulse or a weak pulse in your legs or feet. *Erectile dysfunction in men.

Paget's disease of bone*Pelvis. Paget's disease of bone in the pelvis can cause hip pain. *Skull. An overgrowth of bone in the skull can cause hearing loss or headaches. *Spine. If your spine is affected, nerve roots can become compressed. This can cause pain, tingling and numbness in an arm or leg. *Leg. As the bones weaken, they may bend — causing you to become bowlegged. Enlarged and misshapen bones in your legs can put extra stress on nearby joints, which may cause wear-and-tear arthritis in your knee or hip.

Paget's disease of the breast or nipple*Flaky or scaly skin on your nipple. *Crusty, oozing or hardened skin resembling eczema on the nipple, areola or both. *Itching. *Redness. *A tingling or burning sensation. *Straw-colored or bloody nipple discharge. *A flattened or turned-in (inverted) nipple. *A lump in the breast. *Thickening skin on the breast.

Progressive supranuclear palsy or Steele-Richardson-Olszewski syndrome*A loss of balance while walking. *An inability to aim your eyes properly. *Stiffness and awkward movements. *Falling. *Problems with speech and swallowing.

*Sensitivity to light. *Sleep disturbances. *Loss of interest in pleasurable activities. *Impulsive behavior, possibly including laughing or crying for no reason. *Difficulties with memory, reasoning, problem-solving and decision-making. *Depression and anxiety. *A surprised or frightened facial expression, resulting from rigid facial muscles. pancreatic cancer*Upper abdominal pain that may radiate to your back. *Yellowing of your skin and the whites of your eyes (jaundice). *Loss of appetite. *Weight loss. *Depression. *Blood clots. pancreatic cysts*Persistent abdominal pain, which may radiate to your back. *A mass you can feel in your upper abdomen. *Nausea and vomiting.

PancreatitisAcute pancreatitis signs and symptoms include: *Upper abdominal pain. *Abdominal pain that radiates to your back. *Abdominal pain that feels worse after eating. *Nausea. *Vomiting. *Tenderness when touching the abdomen.

Chronic pancreatitis signs and symptoms include: *Upper abdominal pain. *Losing weight without trying. *Oily, smelly stools (steatorrhea).

Panic attacks or Panic disorder*Sense of impending doom or danger. *Fear of loss of control or death. *Rapid, pounding heart rate. *Sweating. *Trembling or shaking. *Shortness of breath or tightness in your throat. *Chills. *Hot flashes. *Nausea. *Abdominal cramping. *Chest pain. *Headache.

*Dizziness, lightheadedness or faintness. *Numbness or tingling sensation. *Feeling of unreality or detachment.

Paraneoplastic syndromes*Difficulty walking. *Difficulty maintaining balance. *Loss of muscle coordination. *Loss of muscle tone or weakness. *Loss of fine motor skills, such as picking up objects. *Difficulty swallowing. *Slurred speech. *Memory loss and other thinking (cognitive) impairment. *Vision problems. *Sleep disturbances. *Seizures. *Sensory disturbances. *Unusual involuntary movements.

Paraplegia or Spinal cord injury*Loss of movement. *Loss of sensation, including the ability to feel heat, cold and touch. *Loss of bowel or bladder control. *Exaggerated reflex activities or spasms. *Changes in sexual function, sexual sensitivity and fertility. *Pain or an intense stinging sensation caused by damage to the nerve fibers in your spinal cord. *Difficulty breathing, coughing or clearing secretions from your lungs.

Emergency signs and symptoms: *Extreme back pain or pressure in your neck, head or back. *Weakness, incoordination or paralysis in any part of your body. *Numbness, tingling or loss of sensation in your hands, fingers, feet or toes. *Loss of bladder or bowel control. *Difficulty with balance and walking. *Impaired breathing after injury. *An oddly positioned or twisted neck or back.

Parkinson's disease*Tremor, or shaking, usually begins in a limb, often your hand or fingers. *Slowed movement (bradykinesia). * Rigid muscles. *Impaired posture and balance. *loss of automatic movements. *Speech changes. *Writing changes.

Patellar tendinitisThe pain in your knee may:

*At first be present only as you begin physical activity or just after an intense workout. *Worsen until it interferes with playing your sport. *Eventually interfere with daily movements such as climbing stairs or rising from a chair.

Patent ductus arteriosus (PDA)*Poor eating, which leads to poor growth. *Sweating with crying or eating. *Persistent fast breathing or breathlessness. *Easy tiring. *Rapid heart rate.

Peanut allergy*Runny nose. *Skin reactions, such as hives, redness or swelling. *Itching or tingling in or around the mouth and throat. *Digestive problems, such as diarrhea, stomach cramps, nausea or vomiting. *Tightening of the throat. *Shortness of breath or wheezing.

Pectus excavatum*Decreased exercise tolerance. *Rapid heartbeat or heart palpitations. *Recurrent respiratory infections. *Wheezing or coughing. *Chest pain. *Heart murmur. *Fatigue.

Pelvic inflammatory disease(PID)*Pain in your lower abdomen and pelvis. *Heavy vaginal discharge with an unpleasant odor. *Irregular menstrual bleeding. *Pain during intercourse. *Fever. *Painful or difficult urination.

PemphigusPemphigus vulgaris: *The most common form, pemphigus vulgaris usually begins with blisters in your mouth, which then erupt on your skin. Blisters can also break out on the mucous membranes of your genitals.

The blisters typically are painful, but don't itch. Blisters in your mouth or throat may make it hard to swallow and to eat.

Pemphigus foliaceus: *This type doesn't usually affect mucous membranes. The blisters, which usually begin on your face and scalp and later erupt on your chest and back, usually aren't painful. They tend to be crusty and itchy.

Penicillin allergy*Skin rash.

*Hives. *Itching. *Fever. *Swelling. *Shortness of breath. *Wheezing. *Runny nose *Itchy, watery eyes. *Anaphylaxis.

Peptic ulcerpain typically may: *Be felt anywhere from your navel up to your breastbone. *Be worse when your stomach is empty. *Flare at night. *Often be temporarily relieved by eating certain foods that buffer stomach acid or by taking an acid-reducing medication. *Disappear and then return for a few days or weeks.

Other signs and symptoms: *The vomiting of blood — which may appear red or black. *Dark blood in stools or stools that are black or tarry. *Nausea or vomiting. *Unexplained weight loss. *Appetite changes.

Perforated eardrum or ruptured eardrum*Ear pain that may subside quickly. *Clear, pus-filled or bloody drainage from your ear. *Hearing loss. *Ringing in your ear (tinnitus). *Spinning sensation (vertigo). *Nausea or vomiting that can result from vertigo.

Pericardial effusion*Shortness of breath or difficulty breathing (dyspnea). *Discomfort when breathing while lying down (orthopnea). *Chest pain, usually behind the breastbone or on the left side of the chest that often feels worse when you breathe and feels better when you are sitting up, rather than lying down. *Cough. *Low-grade fever. *Rapid heart rate.

Pericarditis*Sharp, piercing chest pain over the center or left side of the chest. *Shortness of breath when reclining. *Heart palpitations. *Low-grade fever.

*An overall sense of weakness, fatigue or feeling sick. *Cough. *Abdominal or leg swelling.

Periodontitis*Swollen gums. *Bright red or purplish gums. *Gums that feel tender when touched. *Gums that pull away from your teeth (recede), making your teeth look longer than normal. *New spaces developing between your teeth. *Pus between your teeth and gums. *Bad breath. *Bad taste in your mouth. *Loose teeth. *A change in the way your teeth fit together when you bite.

Peripheral artery disease or Peripheral vascular disease*Painful cramping in your thigh or calf muscles after activity, such as walking or climbing stairs (intermittent claudication). *Leg numbness or weakness. *Coldness in your lower leg or foot, especially when compared with the other side. *Sores on your toes, feet or legs that won't heal. *A change in the color of your legs. *Hair loss or slower hair growth on your feet and legs. *Slower growth of your toenails. *Shiny skin on your legs. *No pulse or a weak pulse in your legs or feet. *Erectile dysfunction in men.

Peripheral nerve injuries*Tingling and numbness.

Peripheral neuropathy*Gradual onset of numbness and tingling in your feet or hands, which may spread upward into your legs and arms. *Sharp, jabbing or burning pain. *Extreme sensitivity to touch. *Lack of coordination and falling. *Muscle weakness or paralysis if motor nerves are affected.

If autonomic nerves are affected, signs and symptoms may include: *Heat intolerance and altered sweating. *Bowel, bladder or digestive problems. *Changes in blood pressure, causing dizziness or lightheadedness.

Peritonitis*Abdominal pain or tenderness. *Bloating or a feeling of fullness (distention) in your abdomen. *Fever.

*Nausea and vomiting. *Loss of appetite. *Diarrhea. *Low urine output. *Thirst. *Inability to pass stool or gas. *Fatigue.

Pertusis or Whooping cough*Runny nose. *Nasal congestion. *Red, watery eyes. *Fever. *Cough.

Severe and prolonged coughing attacks may: *Provoke vomiting. *Result in a red or blue face. *Cause extreme fatigue. *End with a high-pitched "whoop" sound during the next breath of air.

Pet allergy*Sneezing. *Runny nose. *Itchy, red or watery eyes. *Nasal congestion. *Itchy nose, roof of mouth or throat. *Postnasal drip. *Cough. *Facial pressure and pain. *Frequent awakening. *Swollen, blue-colored skin under your eyes. *In a child, frequent upward rubbing of the nose. *Difficulty breathing. *Chest tightness or pain. *Audible whistling or wheezing sound when exhaling. *Trouble sleeping caused by shortness of breath, coughing or wheezing.

Phantom painPain: *Onset within the first few days of amputation. *Comes and goes or is continuous. *Often affects the part of the limb farthest from the body, such as the foot of an amputated leg. *May be described as shooting, stabbing, boring, squeezing, throbbing or burning. *Sometimes feels as if the phantom part is forced into an uncomfortable position. *May be triggered by pressure on the remaining part of the limb or emotional stress.

Phenylketonuria (PKU)-

*Intellectual disability (formerly called mental retardation). *Delayed development. *Behavioral, emotional and social problems. *Psychiatric disorders *Neurological problems that may include seizures. *Hyperactivity. *Poor bone strength. *Skin rashes (eczema). *A musty odor in the child's breath, skin or urine, caused by too much phenylalanine in the body. *Fair skin and blue eyes, because phenylalanine cannot transform into melanin — the pigment responsible for hair and skin tone. *Abnormally small head (microcephaly).

Pheochromocytomas*High blood pressure. *Rapid or forceful heartbeat *Profound sweating. *Severe headache. *Tremors. *Paleness in the face. *Shortness of breath.

Less common signs or symptoms may include: *Anxiety or sense of doom. *Abdominal pain. *Constipation. *Weight loss.

Thrombophlebitis or PhlebitisSuperficial thrombophlebitis symptoms include: *Warmth, tenderness and pain in the affected area. *Redness and swelling.

Deep vein thrombosis symptoms include: *Pain. *Swelling.

Phobias*A feeling of uncontrollable panic, terror or dread when you're exposed to the source of your fear. *The feeling that you must do everything possible to avoid what you fear. *The inability to function normally because of your anxiety. *Physical as well as psychological reactions, including sweating, rapid heartbeat, difficulty breathing, a feeling of panic and intense anxiety. *Often, the knowledge that your fears are unreasonable or exaggerated but feeling powerless to control them. *In some cases, anxiety just thinking about what you fear. *In children, possibly tantrums, clinging or crying.

Photosensitivity or Polymorphous light eruption or polymorphic light eruptionCharacteristics of the rash may include: *Dense clusters of small bumps. *Raised rough patches. *Redness. *Itching or burning. *Blistering and swelling (less common). *Fever. *Chills. *Nausea. *Headache.

Pilonidal cyst*Pain. *Reddening of the skin. *Drainage of pus or blood from an opening in the skin. *Foul smell from draining pus.

Pilonidal dimple or sacral dimple*A sacral dimple consists of an indentation, or "pit," in the skin on the lower back, just above the crease between the buttocks.

Pinched nerve*Numbness or decreased sensation in the area supplied by the nerve. *Sharp, aching or burning pain, which may radiate outward. *Tingling, "pins and needles" sensations (paresthesia). *Muscle weakness in the affected area. *Frequent feeling that a foot or hand has "fallen asleep".

Pinworm infection*Itching of the anal or vaginal area. *Insomnia, irritability and restlessness. *Intermittent abdominal pain and nausea.

Pituitary tumoursSymptoms related to tumor pressure: *Headache. *Vision loss, particularly loss of peripheral vision. *Nausea and vomiting.

Symptoms of pituitary hormone deficiency: *Weakness. *Less frequent or no menstrual periods. *Body hair loss. *Sexual dysfunction. *Increased frequency and amount of urination. *Unintended weight loss or gain.

Symptoms related to hormone level changes: Adrenocorticotropic hormone-secreting (ACTH) tumors:

*Fat accumulation around your midsection and upper back. *Exaggerated facial roundness. *A characteristic hump on the upper part of your back. *High blood pressure. *High blood sugar. *Muscle weakness. *Bruising. *Stretch marks. *Thinning of your skin. *Anxiety, irritability or depression.

Growth hormone-secreting tumors: *Coarsened facial features. *Enlarged hands and feet. *Excess sweating *High blood sugar. *Heart problems. *Joint pain. *Misaligned teeth. *Increased growth of body hair. *Accelerated and excessive linear growth may occur in children and adolescents.

Prolactin-secreting tumors: In women, prolactinoma may cause: *Irregular menstrual periods *Lack of menstrual periods. *Milky discharge from the breasts.

In men, a prolactin-producing tumor may cause male hypogonadism. Signs and symptoms may include: *Erectile dysfunction (ED). *Infertility. *Loss of sex drive.

Thyroid-stimulating hormone-secreting tumors: *Sudden weight loss. *Rapid or irregular heartbeat. *Nervousness or irritability. *Frequent bowel movements. *Feeling warm or hot.

Pityriasis rosea*Typically begins with a large, slightly raised, scaly patch — called the herald patch — on your back, chest or abdomen. *Before the herald patch appears, some people experience a sore throat or fever. *After the herald patch appears, you may notice smaller scaly spots across your back, chest or abdomen that resemble a pine-tree pattern. *The rash can cause itching, which is occasionally severe.

Pityriasis versicolor or Tinea versicolor*Patches of skin discoloration, usually on the back, chest, neck and upper arms, which may appear lighter or darker than usual. *Mild itching. *Scaling.

Placenta accreta*Causes no signs or symptoms during pregnancy — although vaginal bleeding during the third trimester.

Placenta previa*Bright red vaginal bleeding without pain during the second half of pregnancy is the main sign of placenta previa. Bleeding ranges from light to heavy. The bleeding usually stops without treatment, but it nearly always returns days or weeks later. Some women also experience contractions.

Placental abruption or (abruptio placentae)*Vaginal bleeding. *Abdominal pain. *Back pain. *Uterine tenderness. *Rapid uterine contractions, often coming one right after another.

PlagueBubonic plague: *Sudden onset of fever and chills. *Headache. *Fatigue or malaise. *Muscle aches.

Septicemic plague: *Fever and chills. *Abdominal pain, diarrhea and vomiting. *Bleeding from your mouth, nose or rectum, or under your skin. *Shock. *Blackening and death of tissue (gangrene) in your extremities, most commonly your fingers, toes and nose.

Pneumonic plague: *Cough, with bloody sputum. *Difficulty breathing. *High fever. *Nausea and vomiting. *Weakness.

Plantar fasciitis*Typically causes a stabbing pain in the bottom of your foot near the heel.

Plantar wart*A small, fleshy, rough, grainy growth (lesion) on the bottom of your foot. *Hard, thickened skin (callus) over a well-defined "spot" on the skin, where a wart has grown

inward. *Black pinpoints, which are commonly called wart seeds but are actually small, clotted blood vessels. *A lesion that interrupts the normal lines and ridges in the skin of your foot. *Pain or tenderness when walking or standing.

Pleurisy*Chest pain that worsens when you breathe, cough or sneeze. *Shortness of breath — because you are trying to minimize breathing in and out. *A cough — only in some cases. *A fever — only in some cases.

Primary lateral sclerosis (PLS)*Stiffness, weakness and spasticity in your legs. *Tripping, difficulty with balance and clumsiness as the leg muscles weaken. *Weakness and stiffness progressing to your trunk, then your arms, hands, tongue and jaw. *Hoarseness, reduced rate of speaking, slurred speech and drooling as the facial muscles weaken. *Difficulties with swallowing and breathing late in the disease.

Pneumonia*Fever, sweating and shaking chills. *Cough, which may produce phlegm. *Chest pain when you breathe or cough. *Shortness of breath. *Fatigue. *Nausea, vomiting or diarrhea.

Pneumonitis*Shortness of breath. *Cough. *Fatigue. *Loss of appetite. *Unintentional weight loss.

POEMS syndrome*Polyneuropathy. Numbness, tingling and weakness in your legs — and over time, maybe in your hands — and difficulty breathing. *Organomegaly. Enlarged spleen, liver or lymph nodes. *Endocrinopathy. Abnormal hormone levels that can result in underactive thyroid (hypothyroidism), diabetes, sexual problems, fatigue, swelling in your limbs, and problems with metabolism and other essential functions. *Monoclonal plasma-proliferative disorder. Abnormal bone marrow cells (plasma cells) that produce a protein (monoclonal protein) that can be found in the bloodstream. *Skin changes. More color than normal on your skin, possibly thicker skin and increased facial or leg hair.

Poison ivy rash*Redness.

*Itching. *Swelling. *Blisters.

PolioNonparalytic polio: *Fever. *Sore throat. *Headache. *Vomiting. *Fatigue. *Back pain or stiffness. *Neck pain or stiffness. *Pain or stiffness in the arms or legs. *Muscle weakness or tenderness. *Meningitis.

Paralytic polio: *fever. *Headache. *Loss of reflexes. *Severe muscle aches or weakness. *Loose and floppy limbs (flaccid paralysis), often worse on one side of the body.

Post-polio syndrome *Progressive muscle or joint weakness and pain. *General fatigue and exhaustion after minimal activity. *Muscle atrophy. *Breathing or swallowing problems. *Sleep-related breathing disorders, such as sleep apnea. *Decreased tolerance of cold temperatures. *Cognitive problems, such as concentration and memory difficulties. *Depression or mood swings.

Polycystic kidney disease(PKD)*High blood pressure. *Back or side pain. *Headache. *Increase in the size of your abdomen. *Blood in your urine. *Frequent urination. *Kidney stones. *Kidney failure. *Urinary tract or kidney infections.

Polycystic ovary syndrome (PCOS)*Obesity. *Irregular periods.

*Excess androgen. *Elevated levels of male hormones (androgens) may result in physical signs, such as excess facial and body hair (hirsutism), adult acne or severe adolescent acne, and male-pattern baldness (androgenic alopecia). *Polycystic ovaries. polycythemia vera*Itchiness, especially following a warm bath or shower. *Headache. *Dizziness. *Weakness. *Excessive sweating. *Painful swelling of one joint, often the big toe. *Shortness of breath. *Breathing difficulty when you lie down. *Numbness, tingling, burning or weakness in your hands, feet, arms or legs. *A feeling of fullness or bloating in your left upper abdomen due to an enlarged spleen.

Polyhydramnios*Shortness of breath or the inability to breathe, except when upright. *Swelling in the lower extremities, vulva and abdominal wall. *Decreased urine production.

Polymyalgia rheumatica*Aches or pain in your shoulders (often the first symptom). *Aches or pain in your neck, upper arms, buttocks, hips or thighs. *Stiffness in affected areas, particularly in the morning or after being inactive for a long time, such as a long car ride. *Limited range of motion in affected areas. *Pain or stiffness in wrists or knees (less common). *Mild or low-grade fever. *Fatigue. *A general feeling of not being well (malaise). *Loss of appetite. *Unintended weight loss. *Depression.

Polymyositis*muscle weakness involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck.

Porphyriaacute porphyria: *Severe abdominal pain. *Swelling of the abdomen (abdominal distention). *Pain in your chest, legs or back. *Constipation or diarrhea. *Vomiting.

*Insomnia. *Heartbeat you can feel (palpitations). *High blood pressure. *Anxiety or restlessness. *Seizures. *Mental changes, such as confusion, hallucinations, disorientation or paranoia. *Breathing problems. *Muscle pain, tingling, numbness, weakness or paralysis. *Red or brown urine.

Cutaneous porphyrias: *Sensitivity to the sun and sometimes artificial light, causing burning pain. *Sudden painful skin redness (erythema) and swelling (edema). *Blisters that take weeks to heal. *Itching. *Fragile skin. *Scars or skin color changes from healing blisters. *Increased hair growth. *Red or brown urine.

Post-concussion*Headaches. *Dizziness. *Fatigue. *Irritability. *Anxiety. *Insomnia. *Loss of concentration and memory. *Noise and light sensitivity.

Post-polio syndrome*Progressive muscle and joint weakness and pain. *General fatigue and exhaustion with minimal activity. *Muscle atrophy. *Breathing or swallowing problems. *Sleep-related breathing disorders, such as sleep apnea. *Decreased tolerance of cold temperatures.

Post-traumatic stress disorder(PTSD)Intrusive memories: *Recurrent, unwanted distressing memories of the traumatic event. *Reliving the traumatic event as if it were happening again (flashbacks). *Upsetting dreams about the traumatic event. *Severe emotional distress or physical reactions to something that reminds you of the event.

Avoidance: *Trying to avoid thinking or talking about the traumatic event.

*Avoiding places, activities or people that remind you of the traumatic event.

Negative changes in thinking and mood: *Negative feelings about yourself or other people. *Inability to experience positive emotions. *Feeling emotionally numb. *Lack of interest in activities you once enjoyed. *Hopelessness about the future. *Memory problems, including not remembering important aspects of the traumatic event. *Difficulty maintaining close relationships.

Changes in emotional reactions: *Irritability, angry outbursts or aggressive behavior. *Always being on guard for danger. *Overwhelming guilt or shame. *Self-destructive behavior, such as drinking too much or driving too fast. *Trouble concentrating. *Trouble sleeping. *Being easily startled or frightened.

Postherpetic neuralgia*Pain commonly has been described as burning, sharp and jabbing, or deep and aching. *Sensitivity to light touch. People who have postherpetic neuralgia often cannot bear even the touch of clothing on the affected skin, a condition called allodynia. *Itching and numbness. *Weakness and paralysis.

Postpartum depression*Loss of appetite. *Insomnia. *Intense irritability and anger. *Overwhelming fatigue. *Loss of interest in sex. *Lack of joy in life. *Feelings of shame, guilt or inadequacy. *Severe mood swings. *Difficulty bonding with your baby. *Withdrawal from family and friends. *Thoughts of harming yourself or your baby.

Postpartum hypopituitarism or Sheehan's syndrome*Difficulty breast-feeding or an inability to breast-feed. *No menstrual periods (amenorrhea) or infrequent menstruation (oligomenorrhea). *Loss of pubic or underarm hair. *Slowed mental function, weight gain and difficulty staying warm as a result of an underactive thyroid (hypothyroidism). *Low blood pressure. *Fatigue.

*Irregular heartbeat. *Loss of interest in sex.

Postpartum preeclampsia*High blood pressure (hypertension) — 140/90 millimeters of mercury (mm Hg) or greater. *Excess protein in your urine (proteinuria). *Severe headaches. *Changes in vision, including temporary loss of vision, blurred vision or light sensitivity. *Swelling of the face and limbs. *Upper abdominal pain, usually under the ribs on the right side. *Nausea or vomiting. *Decreased urination. *Sudden weight gain, typically more than 2 pounds (0.9 kilogram) a week.

Postpartum thyroiditisoveractive thyroid (hyperthyroidism): *Anxiety. *Irritability. *Rapid heartbeat or palpitations. *Unexplained weight loss. *Increased sensitivity to heat. *Fatigue. *Tremor. *Insomnia. underactive thyroid (hypothyroidism): *Lack of energy. *Increased sensitivity to cold. *Constipation. *Dry skin. *Difficulty concentrating. *Aches and pains.

Postural hypotension or Orthostatic hypotension*Feeling lightheaded or dizzy after standing up. *Blurry vision. *Weakness. *Fainting (syncope). *Confusion. *Nausea.

Pouchitis*diarrhea, abdominal pain and joint pain, cramps, fever, increased number of bowel movements, nighttime fecal seepage, fecal incontinence, and a strong feeling of the need to have a bowel movement.

Prader-willi syndromeInfants with Prader-Willi syndrome: *Poor muscle tone.

*Distinct facial features. *Failure to thrive. Infants may have a poor sucking reflex due to decreased muscle tone. *Lack of eye coordination (strabismus). *Generally poor responsiveness.

Early childhood to adulthood: *Food craving and rapid weight gain. *Underdeveloped sex organs. *Poor growth and physical development. Children with Prader-Willi *Intellectual disability. *Delayed motor development. *Speech problems. *Behavioral problems. *Sleep disorders. *Scoliosis (abnormal curvature of the spine). *Other endocrine problems. These may include insufficient production of thyroid hormone (hypothyroidism), growth hormone deficiency or central adrenal insufficiency, which prevents the body from responding appropriately during stress or infections.

Other signs and symptoms: *Nearsightedness (myopia) and other vision problems. *Light skin and hair compared with other family members. *High pain tolerance, making it difficult to identify injury or illness. *Problems regulating body temperatures during fever or in hot and cold places.

Precocious pubertySigns and symptoms in girls include: *Breast growth. *First period (menarche).

Signs and symptoms in boys include: *Enlarged testicles and penis. *Facial hair (usually grows first on the upper lip). *Deepening voice.

Signs and symptoms that can occur in boys or girls include: *Pubic or underarm hair. *Rapid growth. *Acne. *Adult body odor.

Preclampsia*Excess protein in your urine (proteinuria) or additional signs of kidney problems. *Severe headaches. *Changes in vision, including temporary loss of vision, blurred vision or light sensitivity. *Upper abdominal pain, usually under your ribs on the right side. *Nausea or vomiting. *Decreased urine output.

*Decreased levels of platelets in your blood (thrombocytopenia). *Impaired liver function. *Shortness of breath, caused by fluid in your lungs.

Preexcitation syndrome or Wolff-Parkinson-White (WPW) syndrome*Sensation of rapid, fluttering or pounding heartbeats. (palpitations). *Dizziness. *Lightheadedness. *Fainting. *Tiring easily during exercise. *Anxiety.

Premature birth*Small size, with a disproportionately large head. *Sharper looking, less rounded features than a full-term baby's features, due to a lack of fat stores. *Fine hair (lanugo) covering much of the body. *Low body temperature, especially immediately after birth in the delivery room, due to a lack of stored body fat. *Labored breathing or respiratory distress. *Lack of reflexes for sucking and swallowing, leading to feeding difficulties.

Premature menopause or premature ovarian failure or primary ovarian insufficiency*Irregular or skipped periods (amenorrhea), which may be present for years or may develop after a pregnancy or after stopping birth control pills. *Hot flashes. *Night sweats. *Vaginal dryness. *Irritability or difficulty concentrating. *Decreased sexual desire.

Premenstrual syndrome(PMS)Emotional and behavioral symptoms: *Tension or anxiety. *Depressed mood. *Crying spells. *Mood swings and irritability or ange.r *Appetite changes and food cravings. *Trouble falling asleep (insomnia). *Social withdrawal. *Poor concentration.

Physical signs and symptoms: *Joint or muscle pain *Headache. *Fatigue. *Weight gain related to fluid retention.

*Abdominal bloating. *Breast tenderness. *Acne flare-ups. *Constipation or diarrhea.

Presbyopia*A tendency to hold reading material farther away to make the letters clearer. *Blurred vision at normal reading distance. *Eyestrain or headaches after reading or doing close work.

Prescription drug abuseOpioid painkillers: *Constipation. *Depression. *Low blood pressure. *Decreased breathing rate. *Confusion. *Sweating. *Poor coordination.

Sedatives and anti-anxiety medications: *Drowsiness. *Confusion. *Unsteady walking. *Poor judgment. *Involuntary and rapid movement of the eyeball. *Dizziness.

Stimulants: *Weight loss. *Agitation. *Irritability. *Insomnia. *High blood pressure. *Irregular heartbeat. *Restlessness. *Impulsive behavior.

Other signs: *Stealing, forging or selling prescriptions. *Taking higher doses than prescribed. *Excessive mood swings or hostility. *Increase or decrease in sleep. *Poor decision making. *Appearing to be high, unusually energetic or revved up, or sedated. *Continually "losing" prescriptions, so more prescriptions must be written. *Seeking prescriptions from more than one doctor.

Preterm labor-

*Regular or frequent contractions — a tightening sensation in the abdomen. *Constant low, dull backache. *A sensation of pelvic or lower abdominal pressure. *Mild abdominal cramps. *Diarrhea. *Vaginal spotting or bleeding. *Watery vaginal discharge (water breaking) — in a gush or a trickle. *A change in vaginal discharge.

Primary aldosteronism*Moderate to severe high blood pressure. *High blood pressure that takes several medications to control (resistant hypertension). *High blood pressure along with a low potassium level (hypokalemia).

Primary biliary cirrhosisCommon early symptoms include: *Fatigue. *Itchy skin. *Dry eyes and mouth.

Later signs and symptoms may include: *Pain in the upper right portion of the abdomen. *Bone, muscle or joint (musculoskeletal) pain. *Yellowing of the skin and eyes (jaundice). *Darkening of the skin that's not related to sun exposure (hyperpigmentation). *Swollen feet and ankles (edema). *Buildup of fluid in the abdomen due to liver failure (ascites). *Fatty deposits on the skin around your eyes, your eyelids, or in the creases in your palms, soles, elbows or knees (xanthomas). *Weak and brittle bones (osteoporosis), which can lead to fractures. *Elevated cholesterol. *Diarrhea that can be greasy (steatorrhea).

Primary immunodeficiency*Frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections. *Inflammation and infection of internal organs. *Blood disorders, such as low platelet counts or anemia. *Digestive problems, such as cramping, loss of appetite, nausea and diarrhea. *Delayed growth and development. *Autoimmune disorders, such as lupus, rheumatoid arthritis or type 1 diabetes.

Primary lateral sclerosis (PLS)*Stiffness, weakness and spasticity in your legs. *Tripping, difficulty with balance and clumsiness as the leg muscles weaken. *Weakness and stiffness progressing to your trunk, then your arms, hands, tongue and jaw. *Hoarseness, reduced rate of speaking, slurred speech and drooling as the facial muscles weaken.

*Difficulties with swallowing and breathing late in the disease.

Primary progressive aphasiaSemantic variant primary progressive aphasia: *Difficulty comprehending spoken or written language, particularly single words. *Difficulty comprehending word meanings. *Difficulty naming objects.

Lopogenic variant primary progressive aphasia: *Difficulty retrieving correct words in speech. *Frequent pauses in your speech while searching for words. *Slow speech. *Difficulty repeating phrases or sentences.

Nonfluent-agrammatic variant primary progressive aphasia: *Difficulty speaking. *Hesitant, halting speech. *Making errors in speech sounds. *Difficulty understanding sentences. *Using grammar incorrectly.

Primary sclerosing cholangitis*Fatigue. *Itching. *Pain in the upper right part of the abdomen. *Fever. *Chills. *Night sweats. *Enlarged liver. *Weight loss. *Yellow eyes and skin (jaundice).

Proctitis*A frequent or continuous feeling that you need to have a bowel movement. *Rectal bleeding. *The passing of mucus through your rectum. *Rectal pain. *Pain on the left side of your abdomen. *A feeling of fullness in your rectum. *Diarrhea. *Pain with bowel movements.

Prostate cancer*Trouble urinating. *Decreased force in the stream of urine. *Blood in the semen *Discomfort in the pelvic area *Bone pain. *Erectile dysfunction.

Prostatitis*Pain or burning sensation when urinating (dysuria). *Difficulty urinating, such as dribbling or hesitant urination. *Frequent urination, particularly at night (nocturia). *Urgent need to urinate. *Pain in the abdomen, groin or lower back. *Pain in the area between the scrotum and rectum (perineum). *Pain or discomfort of the penis or testicles. *Painful orgasms (ejaculations). *Flu-like symptoms (with bacterial prostatitis).

Pseudogout or calcium pyrophosphate deposition diseaseThe affected joints are usually: *Swollen. *Warm. *Severely painful.

Pseudotumor cerebri*Moderate to severe headaches that may originate behind your eyes and worsen with eye movement. *Ringing in the ears that pulses in time with your heartbeat (pulsatile tinnitus). *Nausea, vomiting or dizziness. *Blurred or dimmed vision. *Brief episodes of blindness, lasting only a few seconds and affecting one or both eyes (visual obscurations). *Difficulty seeing to the side. *Double vision (diplopia). *Seeing light flashes (photopsia). *Neck, shoulder or back pain.

Psoriasis*Red patches of skin covered with silvery scales. *Small scaling spots (commonly seen in children). *Dry, cracked skin that may bleed. *Itching, burning or soreness. *Thickened, pitted or ridged nails. *Swollen and stiff joints.

Psoriatic arthritis*Swollen fingers and toes. Psoriatic arthritis can cause a painful, sausage-like swelling of your fingers and toes. You may also develop swelling and deformities in your hands and feet before having significant joint symptoms. *Foot pain. Psoriatic arthritis can also cause pain at the points where tendons and ligaments attach to your bones — especially at the back of your heel (Achilles tendinitis) or in the sole of your foot (plantar fasciitis). *Lower back pain. Some people develop a condition called spondylitis as a result of psoriatic arthritis. Spondylitis mainly causes inflammation of the joints between the vertebrae of your

spine and in the joints between your spine and pelvis (sacroiliitis).

Pulmonary atresia*Blue- or gray-toned skin (cyanosis). *Fast breathing or shortness of breath. *Easily tiring or being fatigued. *Feeding problems, such as tiring or sweating while eating. *Pale, clammy skin that may feel cool to the touch.

Pulmonary edemaSudden (acute) pulmonary edema symptoms: *Extreme shortness of breath or difficulty breathing (dyspnea) that worsens when lying down. *A feeling of suffocating or drowning. *Wheezing or gasping for breath. *Anxiety, restlessness or a sense of apprehension. *A cough that produces frothy sputum that may be tinged with blood. *Chest pain if pulmonary edema is caused by heart disease. *A rapid, irregular heartbeat (palpitations).

Long-term (chronic) pulmonary edema symptoms: *Having more shortness of breath than normal when you're physically active. *Difficulty breathing with exertion. *Difficulty breathing when you're lying flat. *Wheezing. *Awakening at night with a breathless feeling that may be relieved by sitting up. *Rapid weight gain when pulmonary edema develops as a result of congestive heart failure, a condition in which your heart pumps too little blood to meet your body's needs. The weight gain is from buildup of fluid in your body, especially in your legs. *Swelling in your lower extremities. *Fatigue.

High-altitude pulmonary edema symptoms: *Shortness of breath after exertion, which progresses to shortness of breath at rest Cough. *Difficulty walking uphill, which progresses to difficulty walking on flat surfaces. *Fever. *A cough that produces frothy sputum that may be tinged with blood. *A rapid, irregular heartbeat (palpitations). *Chest discomfort. *Headaches, which may be the first symptom.

Pulmonary embolism*Shortness of breath. *Chest pain. *Cough. The cough may produce bloody or blood-streaked sputum. *Leg pain or swelling, or both, usually in the calf. *Clammy or discolored skin (cyanosis). *Fever.

*Excessive sweating. *Rapid or irregular heartbeat. *Lightheadedness or dizziness.

Pulmonary fibrosis*Shortness of breath (dyspnea). *A dry cough. *Fatigue. *Unexplained weight loss. *Aching muscles and joints.

Pulmonary hypertension*Shortness of breath (dyspnea), initially while exercising and eventually while at rest. *Fatigue. *Dizziness or fainting spells (syncope). *Chest pressure or pain. *Swelling (edema) in your ankles, legs and eventually in your abdomen (ascites). *Bluish color to your lips and skin (cyanosis). *Racing pulse or heart palpitations.

Pulmonary valve stenosis*Heart murmur — an abnormal whooshing sound heard using a stethoscope, caused by turbulent blood flow. *Shortness of breath, especially during exertion. *Chest pain. *Loss of consciousness (fainting). *Fatigue.

Pyloric stenosis*Projectile vomiting. *Persistent hunger. *Stomach contractions. *Dehydration. *Changes in bowel movements. *Weight problems.

Pyoderma gangrenosum*Usually starts with a small, red bump on your skin, which may resemble a spider bite. *Within days, this bump can develop into a large, painful open sore. *The ulcers usually appear on your legs, but may develop anywhere on your body. *Small ulcers merge into a large ulcer.