Wor l dAnt i mi cr obi alAwar enessWeek
Ar t i c l e
Rol eofessent i aloi l si nt hef i ght agai nstant i bi ot i cr esi st ance
#EMROGoesUnr i v al ed
Act i onofEssent i alOi l s
Theal t er nat i v et ohi s t or i c alant i bi ot i c si nt hepos t ant i bi ot i cer amus tbean agentt hatpos s es s esant i mi c r obi alac t i v i t yi snont ox i ct ohumansort he env i r onmentanddoesnotc aus es el ec t i onofr es i s t antmi c r obes . Her ec omest heus eofes s ent i aloi l swhi c hhasant i mi c r obi alac t i v i t yandi s av ai l abl e. Ant i mi cr obi alAct i onofEssent i alOi l s: I ti snec es s ar yt os c i ent i f i c al l yr ev i s i tt heanc es t r alpr ac t i c esoft r eat mentof i nf ec t i onsbyar omat i cpl ant sandt hei rex t r ac t s ,wear et al k i ngher eabout Es s ent i alOi l s .Thes eoi l sr es pec tt hec ondi t i onsofnont ox i c i t y ,l owerc os t s , andami ni mum i nhi bi t or yc onc ent r at i ont hati st ool ow! Mechani sm ofAct i on( Bact er i a) : I ti samaj oral t er at i onoft hebac t er i alenv el ope( wal landmembr ane) .
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E. Col iunt r eat ed
E. Col it r eat ed
S.cer vi si aeunt r eat ed
S.cer vi si aet r eat ed
Act i onofEssent i alOi l s
Es s ent i alOi l shav eanons pec i f i cmec hani s m ofac t i on.Oppos i t eof ant i bi ot i c s . Lackofr esi st ancesel ect i on: Nos el ec t i onofbac t er i ar es i s t antt oant i bi ot i c sores s ent i aloi l sandgood ef f ec t i v enes sofEs s ent i alOi l sagai ns tbac t er i ar es i s t antt oABsi nt he I nt es t i nalf l or a. " Boost i ng"pr i nci pl e I thasbeenpr ov ent hatt her ei sas t r ongs y ner gybet weenc er t ai nmai n c ompoundsofes s ent i aloi l sandc er t ai nant i bi ot i c s : Combi neex i s t i ngant i mi c r obi alagent s+ Wi t hac t i v ei ngr edi ent sf r om es s ent i aloi l s . Cl i ni calTr i al s:Ur i nar yt r acti nf ect i on PK/ PDs t udyon56pat i ent s :Pat i ent ss uf f er i ngf r om s i mpl eur i nar yi nf ec t i on wi t hs ens i t i v ebac t er i a St udyon23pat i ent swi t hmul t i r es i s t antger ms :Compl expr of i l es
Pat i entPr of i l es
Tr eat edBact er i a
Pat i ent swi t hbeni gnpr os t at i chy per pl as i a
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Di abet i cpat i ent s
Ac i net obac t eri wof f i
Pat i ent swi t hUr et hr alSt enos i s
Kl ebs i el l apneumoni ae
Pat i ent swhohav eunder goneur i nar ydi v er s i on
Ent er obac t erc l oac ae
Pat i ent swi t hbl adders t ones
Kl ebs i el l aox y t oc a
Pat i ent swi t hbl adderc anc er
Pr ot eusmi r abi l i s
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Act i onofEssent i alOi l s
Concl usi on: Es s ent i aloi l sr epr es entahopet ogr adual l yc l eanupt heani malandpl ant s our c esoft hi ss i l entpandemi candt oi mpr ov et heef f ec t i v enes soft he pr ec i ousex i s t i ngant i bi ot i c sagai ns tmul t i dr ugr es i s t antbac t er i a. Anew dr ughasbeenappr ov edf orof f i c i alus eandi ti sl abel ed" Ol i pen"an as s oc i at i onofAmox i c i l i n,Cl av ul ani cAc i d,andt hees s ent i aloi lCi neol e!
AdnaneREMMALandMohammedAmi neZENOUAKI
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