September 8, 2009 -- The Gazette

o ur 3 9 th ye ar

A N E W TRA D I T I O N

A S UM M ER RITUAL

Covering Homewood, East Baltimore, Peabody,

Candles illuminate the Wyman

More than 500 Johns Hopkins

SAIS, APL and other campuses throughout the

Quadrangle as upperclassmen

picnickers gather for a favorite

Baltimore-Washington area and abroad, since 1971.

welcome freshmen, page 6

end-of-season event, page 7

September 8, 2009

The newspaper of The Johns Hopkins University

J H M I

C E R E M O N Y

Volume 38 No. 2

C A M P U S

A peach of a place

Daniels to be installed as president

By Tracey A. Reeves

Homewood

Continued on page 3

2

HIPS / WILL KIRK

H

is peers know him as a gifted academic leader, noted scholar and energetic collaborator with a passion for engaging global and national minds, as well as those closer to home.

This week, Ronald J. Daniels will add another appellation when he is installed About 700 as the 14th president of The Johns Hopguests are kins University. expected at Daniels, who has served in the post since March, is schedthe event uled to be installed at 2 p.m. on Sunday, on Sunday Sept. 13, in Shriver Hall Auditorium on the Homewood campus. He succeeds William R. Brody, who led the university for 12 years, before retiring in February. Brody, now president of the Salk Institute, is slated to attend, as are two other past presidents, Steven Muller and William C. Richardson.

“This is a profound moment in the history of Johns Hopkins,” said Jerry Schnydman, secretary of the board of trustees and executive assistant to the president, who has served under five of the university’s presidents. “This is only the 14th installation, and each one has resulted in a renewal of purpose, hope and aspirations for this great university.”

Daniels will use the occasion of his installation to lay out his vision for Johns Hopkins and to dedicate himself and the university to the community surrounding its campuses. It will be the first time that Daniels speaks publicly about his plans for the 133-year-old institution.

The inaugural convocation and installation will feature the kind of pomp and circumstance reserved for events like commencement, with participants in full academic regalia. Daniels, formerly provost and chief academic officer of the University of Pennsylvania, will officially receive the presidential

Emily Johnson, second from left, picks up some fresh greens on a Thursday morning.

I

n the shadow of the iconic dome, a fresh and delicious Thursday tradition has taken hold on the East Baltimore campus.

Last Thursday, hundreds of Johns Hopkins staff, faculty, students, patients and community members took time out on a pleasant late summer day to stroll through the new Farmers Market at Johns Hopkins.

Few left empty-handed.

Located on a tree-lined pathway adjacent

Everything’s fresh and local at Farmers Market at Johns Hopkins

By Greg Rienzi

The Gazette

to the Outpatient Center, the market hosts vendors of locally grown and produced fruits, vegetables, flowers, nuts, cheeses, jams, teas, confections, baked goods, pork, poultry, beef and more.

The market, which launched on June 4, offers a bouquet of fresh items, from tomatoes and loaves of wheat bread, to wasabi peanuts and mango chutney. If Continued on page 4

R E S E A R C H

New tool may help docs predict COPD death risk

By Tim Parsons

School of Public Health

R

esearchers have developed an index scale to help physicians predict a patient’s risk of dying from chronic obstructive pulmonary disease, or COPD. The ADO index, they say, can help physicians assess the severity of a patient’s illness

In Brief

Engineering courses for BRAC workers; SAIS’ Year of Religion; Carey School Dean’s Lecture

12

to determine the appropriate level of treatment. COPD, which comprises emphysema and chronic bronchitis, is a major public health problem and is the fourth leading cause of death in the United States. The study of the ADO index is published in the Aug. 29 edition of The Lancet.

Currently, chest physicians estimate a patient’s risk of death from COPD by using the BODE index, which is based on an

C A L E N D AR

Neighborhood block party; East Baltimore blood drive; Sundance winner ‘Burma VJ’

assessment of body-mass index, airflow obstruction, dyspnea and exercise capacity.

However, the BODE index is rarely used in primary care settings, where most patient treatment options are managed, because exercise capacity cannot be easily measured in the typical doctor’s office.

“The burden from COPD is so enormous Continued on page 4

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Carey School’s Dean’s Lecture Series presents fall speaker

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arolyn Woo, dean of the Mendoza College of Business at the University of Notre Dame, is the speaker for the fall 2009 installment of the Carey Business School’s Dean’s Lecture Series. Her talk, “Business Leadership for the Global Commons,” is scheduled for 5 p.m. on Thursday, Sept. 10, in Homewood’s Mason Hall.

Appointed dean in 1997, Woo previously served as associate executive vice president for academic affairs at Purdue University, from which she received her bachelor’s and doctoral degrees. She joined the Purdue faculty in 1981 and directed the Professional Master’s Programs in the Krannert School of Management from 1993 to 1995.

Woo’s research focuses on strategy, entrepreneurship and organizational systems, and her work has appeared in such publications as Academy of Management Journal, Administrative Science Quarterly, Harvard Business Review and Management Science. She serves on the boards of Aon Corp., NiSource, Aileron and Catholic Relief Services and was formerly chair of the AACSB International (Association for Accreditation of Collegiate Schools of Business).

To register for the event, go to carey.jhu .edu/deanslectures. For more information, e-mail carey.lectureseries@jhu.edu.

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hree online courses in systems engineering, designed to prepare workers for jobs coming to Maryland through the federal Base Realignment and Closure process, are being launched by Engineering for Professionals, the part-time graduate program of the Johns Hopkins Whiting School of Engineering.

The new master’s level courses, all developed by EP faculty, are Software Systems Engineering, Tools and Techniques of Software Project Management, and Systems Architecting. Tools and Techniques will be offered this fall; the other two courses are slated for spring 2010.

The online instruction is open to military and civilian personnel, along with members of the general public.

EP began developing the courses after receiving a $140,000 grant in fall 2008 from the Maryland Higher Education Commission to help give workers some of the skills needed for jobs coming to Maryland through BRAC. With this financial support, EP has developed the first of six anticipated online courses in systems engineering, one of several graduate degree areas identified as important for relocated military personnel.

The remaining three courses will be developed by the end of 2009.

The first three courses were recently reviewed by Quality Matters, a facultycentered peer review program. Each was

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller

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recognized as having met or exceeded 17 essential standards in areas such as accessibility, learner engagement and support, and course technology.

EP students are able to fully complete the master’s in systems engineering degree program online. For more information, go to www.ep.jhu.edu/se.

Authors Sung J. Woo, LaDawn Black to visit Barnes & Noble

A

uthors Sung J. Woo and LaDawn Black will be visiting Barnes & Noble Johns Hopkins this week.

Woo is the author of the critically acclaimed Everything Asian, a coming-of-age novel chronicling the world of 12-year-old David Kim, who moves from Korea with his mother and sister to join his father in New Jersey.

His short stories and essays have appeared in The New York Times, McSweeney’s and KoreAm Journal. Woo will sign copies of his novel at 2 p.m. on Saturday, Sept. 12.

Black hosts a radio relationship show, The Love Zone, five nights a week on Baltimore’s 92Q, and she also is a relationship coach for match.com, essence.com and blackmeninamerica.com. Her new book, Tease, with chapters inspired by personal ads, is her first work of fiction. She will discuss it at 7 p.m. on Wednesday, Sept. 9.

SAIS to examine critical role of religion in international affairs

E

ach summer, a subject of special interest is selected at SAIS to serve as a substantive theme in the coming academic year. During 2009–2010, the school will examine the critical role of religion in international affairs.

With events in Iran; the conflicts in Iraq, Afghanistan and Pakistan; the search for lasting peace in Israel-Palestine; and the changing patterns of faith around the globe, religion as a factor in international relations is a timely topic for exploration, SAIS officials said.

The Year of Religion is expected to provide many opportunities for faculty, students and alumni to review scholarship, exchange views and celebrate a diverse set of holidays.

Building on the theme, the 2009 issue of SAISPHERE will focus on the interchange between religion and international relations.

SAIS will partner with the Pew Forum on Religion & Public Life in organizing three panel discussions that examine the diversity of religion in Africa, the spread of Islam through Europe and the demographic characteristics of Islam. Cultural Conversations, a research center at SAIS, will welcome Iranian-American author Haleh Esfandiari, who has written a memoir about her unlawful imprisonment in her home country. Other prominent speakers will be announced throughout the year.

To stay informed of Year of Religion initiatives and events, go to www.sais-jhu.edu/ religion.

Contributing Writers Applied Physics Laboratory Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Audrey Huang, John Lazarou, David March, Katerina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Government, Community and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date.

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September 8, 2009 • THE GAZETTE

Events honoring the installation of Ronald J. Daniels as 14th president of The Johns Hopkins University Friday, Sept. 11 9 to 10:30 a.m. Coffee and pastries

and a chance to greet President Daniels for Homewood campus faculty and staff.

Tent on Wyman Quadrangle.

12:30 to 2 p.m. Ice cream social for

Homewood undergraduate and graduate students. Tent on Wyman Quadrangle.

3:30 p.m. Welcome to President Dan-

iels at the Bloomberg School of Public Health, Sommer Hall, followed by a 4:30 to 6 p.m. reception for students, faculty and staff, Feinstone Hall.

Saturday, Sept. 12 10 a.m. The RD2.5K Presidential Fun

Installation Continued from page 1 insignia, a sterling silver ceremonial necklace engraved with the portraits and names of the presidents of the university and signifying the authority vested in the president by the board of trustees.

About 700 invited guests are expected to attend the event, including Maryland Gov. Martin J. O’Malley, U.S. Rep. Elijah Cummings and Baltimore Mayor Sheila Dixon, as well as a host of officials from peer institutions, including Amy Gutmann, president of the University of Pennsylvania, and 12 other sitting presidents.

The convocation and installation will be preceded by several events meant to recognize the official start of Daniels’ tenure (for details, see related box). On Friday morning, Daniels will greet faculty and staff of the Homewood schools with coffee and pastries and later host an ice-cream social for all Homewood students. Later in the afternoon, the Bloomberg School of Public Health will welcome him.

On Saturday morning, Daniels will join students, faculty, staff and their families for the RD2.5K Presidential Fun Run, a noncompetitive jog through the Homewood campus. In the afternoon, Daniels, along with more than 1,000 members of the Johns Hopkins community, will fan out across the city to take part in a President’s Day of Service, a volunteer effort designed to help clean up and repair city neighborhoods and buildings. Later in the day, the university will host its annual block party, known as Convergence, for its Charles Village neighbors. An inaugural dinner at the Baltimore Marriott Waterfront hotel for invited guests will conclude the day.

A number of the university’s major divisions have planned their own events for later this month and next to welcome Dan-

Run, a noncompetitive jog through the Homewood campus with President Daniels, open to all students, faculty and staff and their families. To pre-register, go to the inauguration Web site, http://web.jhu .edu/administration/president/inauguration/ events.html. Check-in and “day-of” registration are from 8:30 to 9:45 a.m. at the O’Connor Recreation Center. Following the run, there will be refreshments and a raffle, with prizes including a Dell laptop computer, five iPod Nanos and gifts from Barnes & Noble Johns Hopkins.

3 to 6 p.m. Convergence! the annual

neighborhood block party sponsored by the university and area businesses for students and their Charles Village neighbors.

Booths, food, information tables sponsored by university groups and businesses, entertainment and children’s games. Service road in the 3200 block of St. Paul Street.

president/inauguration/ index.html. Reception for guests to follow.

Monday, Sept. 21 5:30 to 7 p.m. Welcome to President Daniels at the Carey Business School, open to the school’s students, faculty and staff. Johns Hopkins Downtown Center.

Tuesday, Sept. 29 8 p.m. President Daniels will be the

vice. Join President Daniels for an afternoon of giving back through volunteer service at 50 sites, including schools, homeless shelters, parks and community gardens

2 p.m. Installation ceremony, by invitation only. Shriver Hall Auditorium, Homewood. A Webcast will be available online on the inauguration Web site, web.jhu.edu/administration/

honored guest at a Peabody Institute concert featuring musicians from the Yong Siew Toh Conservatory, Peabody’s sister conservatory in Singapore. Violinist Qian Zhou (head of Strings at Yong Siew Toh) and pianist Bernard Lanskey (director of Yong Siew Toh) will perform. Griswold Hall. Details are available online at www.peabody .jhu.edu/505?detail=event&id=6168& event_month=2009-09. A reception, by invitation only, will follow.

iels and to give their students, faculty and staff a chance to meet the new president.

The highlight, though, is President Daniels’ installation on Sunday.

The day will begin with brunch for invited guests in the Johns Hopkins Club and the Glass Pavilion. As is customary, the inaugural convocation will begin with a procession of trustees, faculty and special guests, led

by Ben Carson, director of Pediatric Neurosurgery at the Johns Hopkins Children’s Center, in the role of chief marshal. The Rev. Albert Mosley, university chaplain, will deliver the invocation, followed by the national anthem sung by Tariq Al-Sabir, a student at the Peabody Preparatory and a junior at the Baltimore School for the Arts. Pamela Flaherty, chair of the board of trustees, will then welcome and recognize distinguished visitors, and Lloyd Minor, provost and senior vice president for academic affairs, will introduce the greeters.

The co-ed a cappella group Octopodes will perform a selection preceding the installation of Daniels, who will then address his guests. A cocktail reception under a tent on the Wyman Quadrangle will conclude the event.

The 90-minute ceremony will be the culmination of a busy time for Daniels, who took office in early March following his unanimous election by the board last November. Since 2005, Daniels had been provost at Penn, where he was responsible for, among other areas, undergraduate and graduate education, faculty affairs, global initiatives, student life, athletics and admissions. Prior to holding that post, he was dean of the Faculty of Law and James M. Tory Professor of Law at the University of Toronto.

Daniels rose to the top of the list among nearly 300 nominees in the search for Brody’s successor.

“Ron is a strategic thinker, known for articulating and implementing bold and visionary academic ideas and initiatives,” Flaherty said just after Daniels was named Johns Hopkins

president. “He impressed the committee with his passion for the academic enterprise, his record of academic entrepreneurship and his commitment to building excellence in both the basic sciences and multidisciplinary research centers and institutes.”

During his tenure at Penn, Daniels was credited with helping to accelerate the institution’s rise among universities and expanding its global relationships. He also was instrumental in strengthening financial aid opportunities for undergraduate and graduate students. On the faculty side, Daniels established mentoring and leadership development programs for faculty, strengthened appointment and promotion standards, and enriched strategies to recruit and retain faculty, especially among women and underrepresented minorities.

Daniels, who earned an LLM from Yale University and a JD and BA from the University of Toronto, is married to Joanne

Rosen, a human rights lawyer. They are the parents of four teenagers.

In the six months that he has been in the presidential job, Daniels has been a student of sorts, as he gets to know the ins and outs of Johns Hopkins and prepares to embark on his goals and objectives for the university.

His class load has included meetings with deans, faculty and senior administrators, and he has immersed himself in the culture of the Johns Hopkins community.

Daniels has also spent time with state and community leaders in an effort to learn about how Johns Hopkins fits in the broader landscape. G To view a live webcast of the induction ceremony, which begins at 2 p.m. on Sunday, Sept. 13, go to web.jhu.edu/ administration/president/inauguration/index .html. Videos of President Daniels’ speech and of the entire ceremony are scheduled to be available on the inauguration Web site the following day.

12:30 to 5 p.m. President’s Day of Ser-

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4 THE GAZETTE • September 8, 2009

Deaths from unintentional injuries increase for many groups Rate of poisoning mortality triples in white women between ages of 45 and 64

By Tim Parsons

School of Public Health

W

hile the total mortality rate from unintentional injury increased in the United States by 11 percent between 1999 and 2005, far larger increases were seen in some subgroups analyzed by age, race, ethnicity and type of injury by researchers at the Johns Hopkins Bloomberg School of Public Health’s Center for Injury Research and Policy. Their analysis found that white women between 45 and 64 years old experienced a 230 percent increase in the rate of poisoning mortality over the study period, and white men in this age group experienced an increase of 137 percent. The study was published online by the

Market Continued from page 1 the brilliant colors don’t lure you in, the smell will.

Kelly Bower, an instructor in the Department of Community Public Health at the School of Nursing, could not resist a few large red bell peppers.

“They looked so good,” said Bower, who had come to the market once before. “This market is fantastic. It’s so nice to have one right here.”

The market—one of only a handful in the city—is sponsored by the Johns Hop-

American Journal of Preventive Medicine in advance of the September print edition of the journal.

The study also found mortality rates from falls varied widely across age and gender.

The death rate from falls increased 38 percent for white men and 48 percent for white women 65 and older. The mortality rate did not increase significantly for older blacks of either sex. Overall, 89 percent of the total increase in unintentional injury deaths in the United States between 1999 and 2005 was due to poisoning among those 15 to 64 years old and falls among those 45 and older, numbers that increased by about 11,200 and 6,600, respectively.

“The large increases in the number of deaths attributable to poisoning and falls underscore the need for more research on the specific circumstances involved,” said study co-author Susan P. Baker, a professor in the Bloomberg School’s Center for Injury Research and Policy. “While we don’t know the cause behind the recent increase in falls mortality, it appears that

the increase in poisonings is largely due to prescription drugs.”

Baker said that national prevention efforts are needed to control the abuse of prescription drugs and limit access. Prescriptions for opioid analgesics to address pain have increased dramatically in the past decade, and data from the Centers for Disease Control and Prevention show that prescription drugs have replaced illegal drugs such as cocaine as the most prominent substances in fatal drug overdoses.

Senior author Guoqing Hu and Baker analyzed data from the CDC Web-based Injury Statistics Query and Reporting System, which provides data on deaths according to cause and intent of injury. WISQARS mortality data are based on annual data files of the National Center for Health Statistics of CDC. In addition to falls and poisonings, four other leading causes of unintentional injury deaths were identified for subsequent analyses: suffocation, drowning, fire/burns and motor vehicle crashes. Suffocation rates

generally decreased or had no significant change, but they greatly increased in white children less than 1 year old. Drowning rates increased among white men 65 and older and among white middle-aged women, but decreased in black males 5 to 24 years old, black females 5 to 14 years old and white females 15 to 24 years old. Mortality from fires and burns decreased the most. The rate of dying due to a motorcycle crash more than doubled in Hispanic males 15 to 24 years old and in white males ages 45 to 64.

“By teasing out the impact of gender, age and race on trends in mortality rates, we are able to better identify changes worthy of attention from clinicians and policymakers,” Hu said. “As injury continues to be a leading cause of death for all age groups and, in fact, the leading cause of death for adults 44 and younger, it’s critical we redouble our efforts to prevent unnecessary suffering and save lives.”

The research was funded by the Johns Hopkins Center for Injury Research and Policy.

kins Hospital Green Team and supported by the schools of Medicine, Nursing and Public Health and the Kennedy Krieger Institute. Additional support comes from the Maryland Department of Agriculture and Maryland Hospitals for a Healthy Environment.

Co-founders Roneet Mallin and Shannon Gregor, both members of the JHH Green Team, wanted to find a way to bring healthy food options to campus, while also reducing Johns Hopkins’ carbon footprint and supporting the local economy. All the vendors hail from Maryland.

Mallin said that it’s all about convenience and healthy eating.

“At the end of the day, when people are exhausted from work, what is easier to do,

drive through a fast food chain, or go to the store to wait in line and then get home and cook?” said Mallin, a home care coordinator for The Johns Hopkins Hospital.

“Well, if they already had part of the shopping taken care of right here at our farmers market, they are more apt to go home and have a real and healthy meal. We are also doing this to show that we believe in what we are talking about: reducing our carbon footprint, bringing people health choices.

Anyone can come here and get fresh, healthy and tasty food made or grown by local people.”

Don’t look for strawberries right now, however; all the food is seasonal.

“When we started, the produce stands only had a few items because less was growing then,” Mallin said. “But now look at it— just about everything is growing. Later on, it will reduce again. We are teaching people to eat local and seasonal. Everything here is fresh.”

The market is designed to offer all one would need for a full meal: from snacks, such as cheeses and nuts, to meat and vegetables, and desserts.

Mallin said that the response to the market has been “phenomenally fantastic.” The crowds have been consistently large, and early on, the vendors, unprepared for heavy foot traffic, sold out in hours.

Libby Longendorf, manager for Zahradka’s Farm in Essex, said that she’s been going through two large truckloads of produce

every Thursday. “The response to this has been incredible. The first week completely surprised us, the number of people,” Longendorf said. “We’re certainly happy to be here.”

Longendorf staffed her stand solo the first week, but due to demand has since been joined by five other farm employees.

The East Baltimore farmers market is not Johns Hopkins’ first. In 2008, Bayview Medical Center opened its own market, which operates from 10 a.m. to 2 p.m. on Wednesdays on the Hopkins Bayview Circle.

Last Friday, the 32nd Street Farmers Market moved to the Homewood campus’s freshman quad for a day, due to the efforts of the Class of 2010. Affan Sheikh, class president, said that while it was considered a one-time event, the market could return to campus.

“If it’s extremely successful, I feel that the vendors of the farmers market will be more receptive to coming back to campus more often.”

Mallin said that due to the East Baltimore market’s initial success, it will likely be expanded somewhat next year with more vendors.

“This market has been wonderful. It’s succeeded beyond your wildest dreams,” she said. “Personally, I just love it when I see people walking in the hospital halls with items they bought at the market.”

The Farmers Market at John Hopkins is open from 10 a.m. to 2 p.m. every Thursday through October (rain or shine). G

COPD

dicted and observed mortality, compared to the original BODE index, which performed poorly at predicting three-year risk of mortality. The analysis of the BODE index showed a 36 percent relative underprediction in the Swiss cohort and a 39 percent relative overprediction in the Spanish cohort.

COPD affects more than 16 million Americans, and it is the only disease among the top 10 causes of death with a rising mortality rate in the United States. It is predicted to be the third-largest cause of death by 2020 and has already reached worldwide epidemic proportions.

Additional authors of the study are Judith Garcia-Aymerich, Martin Frey, Gerben ter Riet, Josep M. Anto, Alvar G. Agusti, Federico P. Gomez, Roberto Rodriguez-Roisin, Karel G.M. Moons, Alphons G. Kessels and Ulrike Held.

Funding for the research was provided by the Swiss National Science Foundation; Klinik Barmelweid; Fondo de Investigacion Sanitaria Ministry of Health, Spain; Agencia d’Avaluacio de Tecnologia i Recerca Mediques, Catalonia government; Spanish Society of Pneumology and Thoracic Surgery; Catalan Foundation of Pneumology; Red RESPIRA; Red RCESP; Fondo de Investigacion Sanitaria; Fundacio La Marato de TV3; Novartis Farmaceutica, Spain. G

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Continued from page 1 that we need to reach out to any doctors who care for COPD patients. The ADO index can be used in any setting, and we hope that it will serve as a basis for more individualized treatment selection in the near future,” said Milo A. Puhan, associate professor in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health and lead author of the study.

For the study, Puhan and colleagues developed a simplified BODE index and the ADO index, which included age, dyspnea and airflow obstruction. The research team compared the predictions of the BODE index with the three-year risk of all-cause mortality from 232 COPD patients from Switzerland.

The updated BODE index and the new ADO index were then validated with a cohort of 342 COPD patients from Spain.

According to the study, the updated BODE and ADO indices accurately predicted three-year mortality and matched the observed mortality in the Spanish cohort well, with little difference between pre-

September 8, 2009 • THE GAZETTE

5

Drug yields positive response in people with skin, brain cancer B y V a n e s s a W a s ta

Johns Hopkins Medicine

T

he Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with the most common type of pediatric brain cancer, medulloblastoma, also showed tumor shrinkage.

Initial results of the drug trial, conducted at Johns Hopkins in Baltimore, Wayne State University’s Karmanos Cancer Center in Detroit and the Translational Genomics Research Institute in Scottsdale, Ariz., are published online Sept. 3 in the New England Journal of Medicine. The publication also details side effects of the drug, including muscle cramping, hair loss, fatigue and low blood sodium.

The compound, known as GDC-0449, is designed to inhibit the Hedgehog signaling pathway, thought to fuel growth of some cancers. The pathway was named for the oblong hedgehoglike shape of fly embryos when a key gene in the pathway is disrupted.

Related research by Johns Hopkins and Genentech investigators reported online in the Sept. 3 issue of Science Express reveals more findings on the medulloblastoma case.

“We know that both of these cancer types have mutations in Hedgehog pathway genes,

and our results with Hedgehog inhibitors could be the starting point for developing a new type of therapy for these intractable cancers,” said Charles Rudin, associate director for Clinical Research at the Johns Hopkins Kimmel Cancer Center.

In the Phase I clinical study, 33 patients with advanced basal cell skin cancer were treated with GDC-0449, an oral drug made

by Genentech. Of the 33, 18 had metastatic disease spread to other organs, and 15 had locally advanced disease at the original tumor site. Half the patients with metastatic cancer responded to the therapy as measured by tumor regression of 30 percent or more. Nine of the 15 patients with local recurrences also responded to the drug.

The remaining patients had either stable or progressive disease at a median of nearly 10 months follow-up. Analysis of patients’ skin biopsies revealed that the drug inhibited the Hedgehog signaling pathway.

Rudin and his team also gave the drug to one patient with advanced medulloblastoma, as described in a separate case report in NEJM. The patient, whose cancer recurred 18 months after initial surgery and treatment, had tried several additional therapies with no success. Investigators found that samples of his tumor had very high levels of activity in the Hedgehog pathway.

“Within a few weeks of the treatment, the drug had a remarkable effect on the patient,” Rudin said. “He went from being nearly bedridden with significant pain to exercising and having no pain.” Rudin recounted that the patient’s tumor began to regress,

Disclosing financial conflicts of interest may not be enough B y C h r i s t e n B r o wn

lee

Johns Hopkins Medicine

D

isclosure of financial conflicts of interest to potential participants in research is important but may have a limited role in managing these conflicts, according to a new study by Johns Hopkins, Duke and Wake Forest.

The study’s recommendations provide a framework for establishing sound policy and practices for how best to disclose financial conflicts of interest to potential participants in clinical research, said Jeremy Sugarman, senior author of a paper published in the Aug. 27 issue of the New England Journal of Medicine and the deputy director for medicine at the Berman Institute of Bioethics at Johns Hopkins.

The paper drew on five years of research from the Conflict of Interest Notification Study, a $3 million project led by Sugarman and funded by the National Heart, Lung and Blood Institute. Overall, COINS gathered information from thousands of patients, many clinical trial investigators and those charged with the ethical oversight of research.

Clinical investigators have long been urged to disclose their financial interests, through the informed-consent process, to potential participants in a study. But in their NEJM paper, the authors questioned what goal this disclosure is hoping to achieve.

Examples of financial interests include corporate funding for the expense of enrolling a patient in a trial, or a researcher having a consulting contract or stock ownership with corporate sponsors who have a stake in a trial.

“Our study reveals that disclosure to participants by itself is not the remedy that many seek,” Sugarman said. “But

disclosure may have positive effects on people’s satisfaction with and trust in the research process.”

The authors recommend that research participants not be the sole decision makers about the potential risks arising from investigators’ financial relationships. They agreed that disclosure during the consent process should be brief and simple, and that trial coordinators should have the information they need to address questions about financial relationships.

Kevin Weinfurt of Duke University, lead author of the paper, said that “multiple studies show that most research participants want to know about investigators’ financial relationships but that this information often doesn’t change their minds about enrolling.”

The authors said that participants likely won’t fully understand the nature of investigators’ financial interests but that disclosure encourages transparency, often satisfies participants’ perceived right to know and could foster more trust.

If stock ownership is at play, other management techniques in addition to disclosure should be used, the authors said. Simply disclosing this information is insufficient, they said, because research participants are sometimes troubled by investigators’ and institutions’ equity interests in clinical research.

The authors also agreed that those overseeing conflicts of interest should be explicit about their goals and design plans for managing financial interests that include disclosure requirements toward meeting those goals. The recommendations were offered to investigators, institutional review boards, conflict-ofinterest committees and policy-makers.

The study was supported by a grant from the National Heart, Lung and Blood Institute.

he gained weight, and his requirements for blood transfusion improved. Two months later, however, the cancer progressed and drug treatment could not be sustained. He subsequently died.

Additional research, published online in the Sept. 3 issue of Science Express by investigators at Johns Hopkins and Genentech, focuses on how the medulloblastoma tumor became resistant to the Hedgehog inhibitor.

When the cancer recurred, it had acquired a mutation in a gene known as SMO, which encodes the target of the Hedgehog inhibitor drug. This mutation prevents GDC-0449 from binding to its target. In a mouse model of medulloblastoma selected for GDC-0449 resistance, the researchers found a mutation in the very same location in the mouse SMO gene.

Research over the past several years has shown that mutations in genes encoding a family of proteins known as tyrosine kinases are important causes of relapse in cancer patients treated with other targeted cancer therapies, including lung cancer patients treated with erlotinib. Mutations in SMO, like the one found in this patient, may similarly be an important cause of resistance to Hedgehog inhibitors, Rudin said. Researchers are now evaluating strategies for treating cancers with acquired resistance, to try to maintain the initial good responses seen in some patients treated with these drugs.

The Hedgehog gene got its name from scientists who first studied it in fruit flies.

In humans, the Hedgehog pathway has long been known to contain genes that control fetal development and cell growth, and, when altered, the pathway can cause excessive cell growth, a hallmark of cancer.

Investigators have begun a clinical trial of GDC-0449 at several U.S. cancer centers for children with medulloblastoma. The disease is typically treated with surgery, radiation and chemotherapy, which can have severe

side effects. When it recurs, the cancer is often fatal.

Basal cell skin cancer is the most common type of cancer in adults and is often cured with surgery. In a very small percentage of people, it spreads in the body. There are no chemotherapy drugs proven effective in treating metastatic basal cell cancer.

In addition to Rudin, the NEJM study investigators are Christine Hann, John Laterra, Barbara Coleman and Julie Brahmer, all of Johns Hopkins; Daniel Von Hoff, R. Tibes, G. Weiss, M. Borad, of the Translational Genomics Research Institute; Patricia LoRusso, of the Karmanos Cancer Institute; and Robert Yauch, Christopher Callahan, Ling Fu, Thomas Holcomb, J. Reddy, H. Mackey, B. Lum, W. Darbonne, J. Marsters, Jeremy Stinson, Stephen Gould, Frederic de Sauvage and Jennifer Low, of Genentech.

Von Hoff, LoRusso and Rudin have received research funding from Genentech.

Rudin is a grant awardee from Genentech.

LoRusso has received lecture fees for speaking at the invitation of Genentech. Brahmer and Laterra have received consulting fees from Genentech. De Sauvage has received patents in the field of Hedgehog signaling.

GDC-0449 is based on technology licensed from The Johns Hopkins University, and the university is entitled to a percentage of income from the sale of related products.

The Science study researchers are, from Genentech, Robert L. Yauch, Gerrit J. P. Dijkgraaf, Bruno Alicke, Thomas Januario, Christina P. Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A. Callahan, Tracy Tang, J. Fernando Bazan, Zhengyan Kan, Somasekar Seshagiri, Stephen E. Gould, Jennifer Low and Frederic J. de Sauvage; and, from Johns Hopkins, Rudin and Christine Hann.

Rudin received research funding for a GDC-0449 phase I trial and a BioOncology Grant Program Award from Genentech.

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6 THE GAZETTE • September 8, 2009

First Night inducts freshmen into Homewood student body

By Greg Rienzi

The Gazette

I

n a show of unity, nearly 500 upperclassmen joined with the Class of 2013 for a candlelight ceremony on Homewood’s Wyman Quad on Wednesday evening. The ceremony kicked off the inaugural First Night, an opportunity for the upperclassmen to officially welcome and induct the freshmen into the Johns Hopkins student body on the opening day of the academic year.

The event began just before 10 p.m., after the freshmen filed out of the O-A Cappella Show, held in Shriver Hall, and onto the quad that was lined with 100 luminaries.

The crowd totaled 1,300 students.

After a welcome from the Student Government Association, each class president offered advice and good wishes to the Class of 2013. When each finished, his class was asked to light its candles. At the conclusion of the speeches, the upperclassmen used their flames to light the freshmen’s candles, while, on cue, the Gilman tower bell rang.

With all the candles now lit, they were raised in unison. The students then blew out the flames and let out a cheer.

“We saw it as a symbolic passing of the torch,” said Rachel Navarre, coordinator of campus programming in the Office of Student Life. “We never had an opportunity for the upperclassmen to officially welcome the freshman class, so that was part of the reason for starting what we hope becomes an annual tradition.”

After the candle lighting, the campus came alive with class parties. The freshmen went to the Glass Pavilion for ice cream and T-shirts imprinted with a replica of their class banner. The sophomores and juniors went to Levering Court for a bash that featured a DJ and flame jugglers. And the senior class partied at Nolan’s, the dining facility at Charles Commons.

After all the classes’ candles are lit, students raise the flames in unison on the Wyman Quadrangle.

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HIV subtype linked to increased likelihood for dementia

P

atients infected with a particular subtype of HIV, the virus that causes AIDS, are more likely to develop dementia than patients with other subtypes, a study led

by Johns Hopkins researchers shows.

The finding, reported in the September issue of the journal Clinical Infectious Diseases, is the first to demonstrate that the specific type of HIV has any effect on cognitive impairment, one of the most common complications of uncontrolled HIV infection.

HIV occurs in multiple forms, distinguished by small differences in the virus’s genetic sequence and designated by letters A through K. Certain subtypes appear to cluster in particular areas of the world, and others have been associated with different rates of progression to full-blown AIDS. Of the 35 million people living worldwide with HIV, the majority live in sub-Saharan Africa, where subtypes A, C and D dominate.

Nearly half of patients with advanced HIV infections have at least mild cognitive impairments, and about 5 percent have the severe form of cognitive impairment known as dementia.

In earlier research, Ned Sacktor, a professor of neurology at the Johns Hopkins University School of Medicine and a clinician at the Johns Hopkins Bayview Medical Center, and his colleagues found that about 31 percent of patients visiting an infectious disease clinic in the Ugandan capital, Kampala, where subtypes A and D dominate, had dementia. The finding led them to wonder whether patients with different subtypes had different rates of dementia.

Sacktor and his team studied 60 HIV-infected patients from a Kampala clinic. All the subjects had been part of a different study testing the effect of antiretroviral drugs on cogni-

tive impairment but had not begun taking the drugs. After determining each patient’s HIV subtype, the researchers performed a battery of neurological and cognitive tests to assess each patient’s brain function.

As expected, the majority of the patients had HIV subtypes A or D. Of the 33 subtype A patients, the researchers determined that

Related Web sites Ned Sacktor:

www.hopkinsmedicine.org/neurology _neurosurgery/experts/team_member _profile/37D60115A5A2EF0013ECA 0BB627B797A/Ned_Sacktor

Neurology and Neurosurgery at Johns Hopkins:

www.hopkinsmedicine.org/ neurology_neurosurgery seven had dementia, or about 24 percent. Of the nine patients with subtype D, however, eight had dementia, about 89 percent.

“We were amazed to see such a dramatic difference in dementia frequencies between these two subtypes,” Sacktor said. “If this is the case in all of sub-Saharan Africa, HIVassociated dementia may be one of the most common, but thus far unrecognized, dementias worldwide.”

The research suggests that some biological property of each subtype seems to influence the likelihood that infected patients will develop dementia, Sacktor said. He and his team hypothesize that subtype D may cause more inflammation and injury in the brain, a possibility they are currently investigating.

—Christen Brownlee

September 8, 2009 • THE GAZETTE P I C N I C

An end-of-summer ritual

By John Black

Faculty, Staff and Retiree Programs

T

he prospect of stormy weather could not deter attendees of the 2009 Johns Hopkins Picnic from coming out for a fun afternoon with great food, a DJ, dancing and kids’ games. With breaks in the rain, more than 500 members of the Johns Hopkins community were able to enjoy the annual end-of-summer event, held this year on Aug. 28 on the grounds of Johns Hopkins at Eastern.

The picnic, sponsored by the Office of the Senior Vice President for Finance and Administration and organized by the Office of Faculty, Staff and Retiree Programs, would not be possible without the help of staff and faculty volunteers.

Among the 60-plus who served food, ran children’s activities and staffed the gates were Charlene Hayes, vice president for human resources; Ed Roulhac, vice provost for academic services; and Stephanie Reel, vice provost for information technology and chief information officer. FSRP Director Jeff Pratt offered special thanks to the Facilities and Plant Operations staff who worked the event, the multitude of cheerful volunteers and the offices that donated their time and talent to make the 2009 picnic a success.

PHOTOS BY HIPS/WILL KIRK

Michelle Thomas, Rhian Howard and Diane Jennings

Eugene Mobley and daughter Angela

Wasiu Choudhary and Amy Faby

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Hester Liu, Haiping Hao, Cordelia Hao and Scarlett Hao

Nate Haskins, Myah Myers and Christin Haskins

Betsy Mayotte, Ed Roulhac and Scott Zeger

Norman Henry, Sharon Henry and Barbara Lake Stephanie Reel and Charlene Hayes

The Jones family

7

8 THE GAZETTE • September 8, 2009

September 8, 2009 • THE GAZETTE

9

Patient perception is vital when reporting medical errors

W

hen reporting medical errors, patients’ perceptions of their physicians’ disclosure may be key to gaining their trust, according to researchers from the Johns Hopkins Bloomberg School of Public Health. However, a positive perception of the disclosure has little effect on the lawsuit risk a physician faces.

Researchers examined volunteer responses to several videos depicting the disclosure of an adverse event along with variations in the extent to which a physician accepted responsibility. They found that a patient’s perception of what was said was more important than what was actually said by the physician. In addition, researchers found that in this study a full apology and acceptance of responsibility by the physician in error was associated with better ratings and greater trust. The results are published in the Sept. 1 issue of the Journal of General Internal Medicine.

“Viewers were more likely to want to sue physicians who offered an incomplete apology or who did not accept responsibility,” said Albert Wu, lead author of the study and a professor in the Bloomberg School’s Department of Health Policy and Management. “When viewers thought that the doctor had apologized and taken responsibility, they gave the doctors much higher ratings, with 81 percent of viewers reporting trusting the physician and 56 percent reporting they would refer the physician. However, despite the positive reaction to perceived apology or responsibility, viewers were only slightly less inclined to want to sue.”

Researchers showed 200 adult volunteers from Baltimore City videotaped vignettes that depicted physicians disclosing to patients one of three adverse events. The vignettes varied in the extent of the physicians’ apology and acceptance of responsibility. Viewers were then asked to evaluate

the physicians. Actors were used to create the adverse events, which included a yearlong delay in noticing a malignant-looking lesion on a mammogram, a chemotherapy overdose 10 times the intended amount and a slow response by a pediatric surgeon to pages for a patient who eventually goes into cardiac arrest and is rushed to emergency surgery.

Apology variations were full, nonspecific and none, while responsibility variation was limited to full and none. Wu, along with colleagues from the Johns Hopkins School of Medicine and the University of Florida, examined the relationship between the designed and perceived variations to responses and to account for differences in viewer demographic characteristics.

Peter Pronovost, a co-author of the study, said, “There is broad consensus that physicians and health care organizations should disclose adverse events to patients and their

families. Our findings show that the perception of what is said is more strongly associated with how physicians were perceived.

“Training is needed to help those in practice and training carry out the difficult task of disclosing adverse events,” said Pronovost, a professor in the Bloomberg School’s Department of Health Policy and Management and the Johns Hopkins School of Medicine. “Moving forward, it will be important to evaluate the effectiveness of that training, including how it is perceived by patients and their families.”

The study was written by Wu, I-Chan Huang, Samantha Stokes and Pronovost.

The research was supported by the MCIC Vermont and the Agency for Healthcare Research and Quality.

—Natalie Wood-Wright A sample of the videos used in this study can be found at www.jhsph.edu/dept/hpm/research/ Wu_video.html.

Surgical scrub solution: Good for critically ill patients, too Chlorhexidine bathing is cheap, effective means of protection from superbugs

G

iving critically ill hospital patients a daily bath with a mild, soapy solution of the same antibacterial agent used by surgeons to “scrub in” before an operation can dramatically cut down, by as much as 73 percent, the number of patients who develop potentially deadly bloodstream infections, according to a recent study by patient safety experts at The Johns Hopkins Hospital and five other institutions.

Bloodstream infections, they say, strike as many as one in five patients in hospital intensive care units and increase their chances of dying by as much as 25 percent.

Even when not fatal, such infections have been reported to lengthen hospital stays by an average of a full week and add as much as $40,000 in costs.

The new study, described in the June issue of the journal Critical Care Medicine, tracked daily neck-to-toe sponge baths with a mild, 4 percent solution of chlorhexidine glutonate given to 2,650 ICU patients at six U.S. hospitals. Chlorhexidine glutonate is the antibacterial agent used by surgeons to scrub themselves before an operation and by dentists as a potent mouthwash to guard against gum disease. Weekly swab testing found 32 percent fewer patients colonized with methicillinresistant Staphylococcus aureus, or MRSA, and 50 percent fewer cases of vancomycin-resistant Enterococci, or VRE, when compared to a similar number of ICU patients (2,670) at the same hospitals who were washed with plain soap and water. MRSA and VRE are the two most common so-called “hospital superbugs.”

“Doing everything possible to ward off bloodstream infections and halt the spread of these dangerous bacteria is essential to safeguarding our patients’ well-being, encouraging their speedy recovery and sparing valuable hospital resources,” said study co-investigator Trish Perl, director of Hospital Epidemiology and Infection Control at The Johns Hopkins Hospital.

“It’s just as important to find the right soap to prevent infection as it is to find the right drug to treat patients who develop an infection,” said Perl, also a professor of medicine and pathology at the Johns Hopkins University School of Medicine.

“Our results show that using chlorhexidine [glutonate] as a daily washing agent is a simple, effective and relatively cheap way to protect the health of our most vulnerable patients,” she said. A 320-ounce bottle of the scrub solution costs as little as $6 a bottle. It is also available in packets, as a solid bar or in milder baby wipe–type cloths.

Perl says the goal is to “actively remove” bacteria that may be harmful to the patient or other patients in the hospital, people at

greater risk of infection because of a weakened immune system or from use of medical devices that may offer a route for bacteria to enter the body.

“Because these bacteria have built up resistance to many of the most common antibiotic drugs used to kill them, our goal is to stop them from infecting patients or from spreading from patient to patient, as we are left with few options for treatment after they colonize and then infect a patient,” said Perl, pointing out that the chemical’s antibacterial effects can last from six to 48 hours, depending on the strength of the solution.

“And altering the daily bathing routine is a simple and effective means of doing so because it involves no additional workload for nurses,” she said.

The study showed no skin rashes or adverse events during the test period, between December 2004 and January 2006. Each critically ill patient was tested for infectious bacteria within 48 hours of admission and then weekly thereafter with either nasal or buttock swabs, and for the remainder of their hospital stays.

Among some 500 patients whose stay in hospital was long (at least 10 days), 11 who were washed with chlorhexidine

had MRSA, and five developed bloodstream infections. By contrast, MRSA was detected in 27 of a similar group who were bathed with plain soap, with eight developing bloodstream infections. Similarly, with VRE, nine patients in the chlorhexidine group had bloodstream infections, while 33 were infected in the plain-soap group.

As part of routine hospital procedures, patients found to be infected or to be a carrier before infection has set in are placed in isolation for the remainder of their stay.

Wound care is done only in designated, confined treatment spaces or separate rooms, and hospital staff must take special precautions between treatments, such as cleaning equipment and furniture with strong disinfectants and wearing disposable gloves, masks and gowns.

Perl said that chlorhexidine has been in use since the 1950s but its practical value had “not been appreciated” until now, citing the chemical’s occasional use as a treatment for recurrent pimples as the main reason why the multicenter research team conducted the latest study.

“Our research is particularly important for preventing MRSA and other drug-resistant infections in children,” she said. Her team’s

research in 2007 showed that children admitted to Johns Hopkins are increasingly identified as harboring MRSA or VRE, with four times as many children admitted to the pediatric ICU with MRSA and twice as many with VRE than five years ago.

In 2006, the Joint Commission estimated that 70 percent of the bacteria that cause infections for 2 million hospitalized Americans each year are resistant to at least one of the drugs most commonly used to treat them.

Perl’s only caution, she said, is the need for long-term monitoring to make sure that hampering the growth of one kind of bacteria does not promote the growth of other kinds.

Funding for the study was provided by the Centers for Disease Control and Prevention.

Another Johns Hopkins researcher involved in this survey was Kathleen Speck.

—David March

International Reporting Project Fellows selected for 2009

By Felisa Neuringer Klubes

SAIS

T

en U.S. journalists have been awarded International Reporting Project Fellowships at Johns Hopkins SAIS for the 2009 program, including four journalists focusing on global environmental topics and three on stories dealing with loose nuclear materials.

The nine-week fellowships, which provide mid-career U.S. journalists with opportunities to do in-depth overseas reporting projects, began in late August.

The IRP Fellows, their affiliations and the countries from which they will report are Perry Beeman, environment reporter for The Des Moines Register, Rwanda; Theresa Bradley, freelance journalist, Brazil; Joanna Kakissis, freelance journalist, Bangladesh; Miranda Kennedy, freelance journalist, India; Julia Lyon, reporter for The Salt Lake Tribune, Thailand; Tara McKelvey, senior editor of The American Prospect, Russia; Amna Nawaz, producer for NBC News, Pakistan; Jessica Silver-Greenberg, staff editor of BusinessWeek, Kenya; Joby Warrick, national staff reporter at The Washington Post, Middle East; and Sharon Weinberger, freelance journalist, Georgia.

“Global environmental coverage has been a major focus of our program for years,” said John Schidlovsky, IRP director. “With the global climate change conference in Copenhagen coming up this December, we’re delighted that we’ll be underwriting so many timely stories on international environment-related issues.”

Judges for this year’s competition were David Lamb, contributing writer for Smithsonian and a 2001 IRP Journalist in Residence; Tyler Marshall, a former Los Angeles Times foreign correspondent; Katie Thomas, a reporter with The New York Times and 2006 IRP Fellow; Louise Lief, deputy director of the IRP; and Schidlovsky. The competition attracted a record number of nearly 200 applications.

Since its founding in 1998, the International Reporting Project has enabled more than 300 U.S. journalists to pursue reporting projects from more than 90 countries.

Hundreds of their prize-winning stories have appeared online, on TV and radio, and in newspapers and magazines.

The next deadline for applications for IRP Fellowships is April 1, 2010, for the program to be conducted in fall 2010. For more information, call 202-663-7761, e-mail irp@jhu .edu or go to www.internationalreporting project.org.

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10 THE GAZETTE • September 8, 2009 P O S T I N G S

Job Opportunities The Johns Hopkins University does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or other legally protected characteristic in any student program or activity administered by the university or with regard to admission or employment.

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Secondhand smoke levels higher in cars than in bars or restaurants

By Tim Parsons

School of Public Health

T

he concentrations of secondhand smoke are significantly higher in cars than concentrations generally measured in bars, restaurants and other public places that allow smoking, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.

The study is among the first to measure smoking in cars under real-world driving conditions and was published online Aug. 24, ahead of print, in Tobacco Control.

For the study, researchers monitored the air in the cars of 17 smokers and five nonsmokers. “Two air monitors were placed in each car for a 24-hour period,” said study author Miranda Jones, a master’s student at the Bloomberg School, who conducted the study as part of her Diversity Summer Internship Program.

The cars were driven as the participants commuted to and from work for at least 30 minutes. The median air concentrations measured were 9.6 µg/m3 (micrograms per cubic meter). After one to three cigarettes, airborne concentrations of nicotine were 72 times higher than in smoke-free cars. After adjusting for factors such as air conditioner use, vehicle size, window opening and sampling time, there was a 1.96-fold increase in air nicotine concentrations per cigarette smoked.

Study participants also were surveyed on their knowledge of and attitudes regarding health risks of secondhand smoking and relevant regulations/legislation.

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“Fifty-three percent of the smokers surveyed said that being unable to smoke in the car would help them to quit smoking altogether,” Jones said.

Ninety-three percent of smokers agreed that motor vehicles should be smoke-free on a voluntary basis, but only 7 percent of smokers agreed that vehicles should be smoke-free by regulation. All of the study’s participants—smokers and nonsmokers— agreed that smoking in the car posed a health risk to passengers.

“Involuntary exposure to secondhand smoke accounts for thousands of cases of respiratory, cardiovascular and cancer deaths in the U.S. every year,” said study author Ana Navas-Acien, assistant professor in the Bloomberg School’s Department of Environmental Health Sciences and the Institute for Global Tobacco Control.

“While some states have smoke-free regulations, the high air nicotine concentrations measured in this study support the urgent need for smoke-free education campaigns and legislative measures banning smoking in motor vehicles when passengers, especially children, are present,” she said.

Co-author Patrick Breysse, professor in the Bloomberg School’s Department of Environmental Health Sciences, said, “There is no known safe level of exposure to secondhand smoke. Because smoking in cars can contaminate the entire vehicle, exposure to hazardous components of secondhand smoke can occur long after smoking has stopped,” he said.

Jie Yuan also contributed to the study.

The research was funded by a Clinical Investigator Award from the Flight Attendant Medical Research Institute.

PT nanny, infant-qualified, experienced w/ all ages, CPR/first-aid training, refs avail.

443-469-0972 or chessline.solomons@gmail .com.

Affordable tennis lessons from top-10 Md player, special price for Hopkins staff, students and their families. frana2010@yahoo .com.

Pet-sitter (or house-sitter without pets) avail for Baltimore area, will be able to visit twice a day, I have experience w/cats and sm to med dogs, refs avail, fee depends on specific situation. 443-742-0469 or ljeart@ gmail.com.

Wanted: Tutor to help me prepare to take GMATS. John, 607-592-3444.

NYC bus trip, Sat, Dec 5, depart Towson 7:30am, Fallston 7:45am and Delaware House, 8:10am, arrive NYC about 10:30 am and depart 7pm. $50 (if paid by Sept 30, $55 after). 410-206-2830 or nlheyls@yahoo.com.

Affordable landscaper/certified horticulturist can maintain existing gardens, also design,

plantings, masonry; free consultations. 410683-7373 or grogan.family@hotmail.com.

Tutor avail: All subjects/levels; remedial, gifted and talented; also college counseling, speech and essay writing, editing, proofreading. 410-337-9877 or i1__@hotmail.com.

Friday Night Swing Dance Club, open to public, no partners necessary. 410-583-7337 or www.fridaynightswing.com.

I can help with your JHU retirement plan investments portfolio! Free consultations.

410-435-5939 or treilly1@aol.com.

Expert resume writing, 15 yrs’ experience, specialize in prof’l resumes and students seeking first job/internship, current sale for undergrads. www.resumesbychristina.com.

Multi-family yard sale: Sat, Sept 12, 7am1pm (rain date: Sunday), 3405 Greenway (between University Pkwy and 34th St, in courtyd between Geneva and Eden Hall condos).

Piano lessons w/experienced teacher, Peabody doctorate, all levels/ages welcome. 410662-7951.

Housekeeper needed for 3BR, 1BA RH in Charles Village, 2-3 times a month, clean/ vacuum flrs, dust, clean kitchen and BA, hrs flexible. 202-870-0234 or jrbowman@ hotmail.com.

Looking for friendly student to provide Mandarin tutoring for 10-yr-old, tutor would teach mainly in Mandarin, but must offer English translations as needed, Sat afternoons/Sunday mornings. Wendy, 410-9081602 or wendyyyap@yahoo.com.

September 8, 2009 • THE GAZETTE

Classifieds

M A R K E T P L A C E

APARTMENTS/HOUSES FOR RENT

ing rm, AC, W/D, prkng, nr JHU shuttle/ MTA. $1,150/mo. 410-591-2611.

Baltimore Co (Middlesex), lg 3BR, 1.5BA TH, CAC, fin’d bsmt, must have very good credit. $1,100/mo + sec dep. 443528-5024.

Patterson Park, 2BR, 1.5BA house, hdwd flrs, crpt upstairs, stainless steel appls, skylight, expos’d brick, 1.25 mi to JHMI. $1,100/mo.

443-286-4883.

Bayview area, 2BR apt, W/D, fin’d bsmt, prkng pad, no pets, sec dep + utils. Mary, 443-798-8652.

Pikesville, beautiful 2BR, 1.5BA house w/yd, walk to subway. $1,550/mo + utils + sec dep. jaxbhpr@gmail.com.

Canton, rehabbed 2BR, 1.5BA TH, CAC, W/D, stainless steel appls, granite countertops, bsmt storage, rooftop deck, pets welcome. 410-375-3298.

Pikesville, 1BR, 1BA apt, 1,100 sq ft, W/D, CAC/heat, dw, w/w crpt, walk-in closet, storage rm, cable- and phone-ready, gym/pool access, prkng, nr groceries/restaurants/medical and dental clinics, nr metro. $1,039/mo or 443-870-3481 or alcuasay@yahoo.com.

Canton (Lighthouse Point), 2BR, 2BA waterfront condo w/garage. $1,995/mo. sres1@comcast.net.

Canton, beautiful, rehabbed 2BR, 2.5BA TH, conv to JHH, great location. $1,700/ mo. Courtney, 410-340-6762.

Cedarcroft, 3BR, 1.5BA TH, dw, W/D. $1,250/mo + utils. 410-378-2393.

Charles Village, 1BR, 1BA condo, newly painted, spacious living rm, dining area, full kitchen, patio, nr JHMI shuttle. $1,100/mo + elec. 443-858-9118 or cv.condo@yahoo .com.

Charles Village (2907 St Paul St), 1BR apt in safe, quiet neighborhood, hdwd flrs, off-street prkng avail w/added fee, avail 9/1. $850/mo incl heat, water. murilo_silvia@ hotmail.com.

Ednor Gardens, 3BR house close to JHU/ YMCA/Giant, perf for grad student and postdocs. $1,200/mo. 410-499-3163 or stu_ merkel@yahoo.com.

Glen Burnie waterfront, furn’d 2BR, lg decks, pier and boat lift avail. $1,795/mo.

443-997-5657.

Hampden, 2BR, 1.5BA EOG TH w/renov’d bsmt, W/D, CAC, nr JHU and lt rail, fenced yd. $950/mo. ghefter@hotmail.com.

Hampden, 1BR, 1BA apt on quiet, treelined street, open flr plan, huge kitchen, lots of natural light, hdwd flrs, dog-friendly. Alan or Jay, 410-602-0240.

Hampden, 3BR, 1.5BA house, partly furn’d, CAC, W/D, walk Homewood campus, perf for grad students/faculty. $1,600/mo. 410889-8287 or swallace1971@live.com.

Mt Vernon, 2BR apt, 3rd flr, living rm, din-

Condo Sale by Owner - 2BD/2BA, Charles Vllg./steps from JHU, shops, restaurants. Pre-war, Georgian interiors, orig. HWD flrs., molding, brick FP, euro/ modern kitch., ceramic tile floors, Zodiaq countertops/SS app., renov. BA’s & bonus sunroom, DR w/French doors, foyer, new Energy windows & AC., 1 pkg. space, security system.

Towson Gate (3 Southerly Ct), 2BR, 2BA condo, 1,500 sq ft, sunrm, minimum 1-yr lease, avail 10/1. $1,300/mo. Lily Lin, 410404-3725.

Upper Fells Point, updated 2BR, 2.5BA TH, 3-story, W/D, storage, huge yd, walk to JHH/ Fells Point/Patterson Park, avail September 1, 1-yr lease. $1,545/mo. Jana, 707-315-6450 or Allison, 203-500-4338.

Upper Fells Point, 2BR, 1BA apt, W/D, CAC, dw, kitchen, living rm, gated fence, backyd, mins to JHH. 410-733-4622.

Lg 2BR, 2BA condo w/front desk, pool, balcony, CAC, steps from JHMI shuttle, all utils incl’d. 2BRunione@gmail.com.

Historic 4BR apt, 2,000 sq ft, newly updated, W/D, hdwd flrs, bsmt laundry, garage, offstreet prkng, walk to park, nr shops/bus/ metro/I-83. $1,300/mo + utils. Brian, 443326-3300.

1BR apt in gated community, updated, incl prkng, swimming pool, tennis, nr hospital/ university. $1,200/mo incl utils. 412-6925325 or asrinat1@gmail.com.

419 Chadford Rd (off Homeland Ave), luxury 3BR, 2.5BA TH w/garage, in gated community, swimming pool, nr Gilman/Friends/ Roland Park schools/Notre Dame/Loyola and Hopkins. $2,000/mo. Ash, 443-386-6288.

Roland Park (“Alonsoville”), 6BR, 3.5BA colonial w/gourmet kitchen, CAC, huge rms, sunrm, fin’d bsmt, in Roland Park school zone, walk to JHU. $599,000. 410366-2166 or 429wingate.blogspot.com.

Wyman Park (JHU/BMA area), fully renov’d 3BR, 2BA TH w/hdwd flrs, CAC/ heat, 2-car garage. $299,900. 410-581-4939 or syakov@yahoo.com.

CARS FOR SALE

’07 Honda Civic hybrid, automatic, magnetic pearl color, AC, cruise, AM/FM, MP3 CD, ABS brakes, power windows, fully loaded, excel cond, 31K mi. $19,500/best offer. billauckland@yahoo.com. ’99 Toyota Camry LE, automatic, power everything premium sound, ABS brakes, excel cond, 134K mi. $4,200. 410-710-7665 or cmcvivek@yahoo.com.

ITEMS FOR SALE ROOMMATES WANTED

Share single-family house w/busy prof’l, lg yd, cable, Internet, W/D, prkng, nr JHU shuttle/YMCA/shopping, dogs OK. $650/ mo incl utils. 410-952-2153.

Share 3BR, 2.5BA penthouse apt in Hampden, off the Avenue, W/D, CAC, lg kitchen, deck, own BA. $790/mo + utils + sec dep ($765). 443-904-1651 or janineers19@ yahoo.com.

Rms avail in new TH, no smoking/no pets, walking distance to JHMC. $500/mo + 1/3 utils. 301-717-4217 or xiaoningzhao1@ gmail.com.

F wanted for rm and BA in luxury Bolton Hill condo, secure bldg, many amenities, sm pet OK, common areas fully furn’d, tenantspecific cabinet space in kitchen, gym in bldg, walk to JHU shuttle, owner occupant travels often. $600/mo + sec dep + half-elec ($45). 410-669-7901 or kfi10@msn.com.

Hoover Wind Tunnel 2 vacuum cleaner w/ bags, rated #1 by Consumer Reports. 410-4675636 or chazmeyers47@hotmail.com.

Timbernest loft twin bed, high-quality, 2 yrs old, needs mattress, buyer must pick up (bed will be disassembled). $150. Carol, 443-3868477 or geedle@verizon.net.

Mattress and boxspring, used 5 mos, ready for pickup. $120/best offer. 443-616-6316 or guldanecengiz@gmail.com.

Glass-top table, 45" round, lt wood base, $40; desk chairs (3), $15/ea. 410-825-8349.

Stereo speakers and mixer, $35; Epson Photosmart printer and scanner, $50. qinyingtan @gmail.com.

Beach chairs (2), digital piano, reciprocating saw, 3-step ladder, stool, chair, computer, printer, microwave. 410-455-5858 or iricse .its@verizon.net.

Nonsmoker wanted for Federal Hill house w/ garage and roofdeck, must have good credit and refs. $700/mo + 1/2 utils. 443-857-3166 or ilaoforscience@gmail.com.

Everything must go! Kitchen items, office, living rm, bedroom furniture and accessories. 443-632-6632 or mmostovoy@gmail .com.

Cross Keys Village, 1BR condo in gated community, renov’d BA and kitchen, granite countertops, CAC/heat, pool, covered prkng, great patio w/treetop view. 443-858-0854.

Furn’d 1BR w/own BA in 3BR Fells Point apt, W/D, free Internet access, safe street, 15-min walk to SoM, compensation for monthly bus pass avail for student and postdoc. $400/mo + utils. xzhan45@gmail.com.

Upright piano, pecan wood, excel sound, $1,100; Pearl drum set, $800; Winsten tenor sax, $100; Yamaha keyboard, $80; amps, $40; Ikea “Dalselv” bedframe, full size, $50.

410-235-2522.

F wanted for peaceful, furn’d 3BR, 2BA house, short-term lease OK. $550/mo incl wireless, utils and prkng. skbzok@verizon .net.

Queen sleep sofa and loveseat, in good cond, mattress still sealed in orig plastic cover. $350. sofas4sale@earthlink.net.

Cross Keys Village, 1BR condo w/hdwd flrs, CAC/heat, free prkng, 24-hr security, swimming pool. $136,888. 646-284-2279 or tamrirev@yahoo.com.

we serve halal meat

Lg BR, priv half-BA in shared Randallstown house, huge closet, free wireless Internet. $550/mo + 1/3 utils. ammagnan@hotmail .com.

Sun-Wed: 11:30am-11pm Thurs-Sat: 11:30am -2:30am

Johns Hopkins / Hampden

Studio Apts. available from $800 per month and includes gas, water, heat and optional furniture for an 8-12 month lease term.

Roland Park, gorgeous 2BR co-op next to Homewood campus, short walk to JHMI shuttle. $148,000. 443-615-5190.

Nonsmoker wanted for furn’d BR/priv BA in 3BR house, Carney area, share w/young M prof’l, lg kitchen, laundry on premises, deck, no smoking/no pets. $550/mo incl cable, Internet. Teresa, 443-850-3520 or tufano@ gmail.com.

Butchers Hill/Canton, newly rehabbed 2BR, 1BA TH, stainless steel appls, granite, hdwd flrs, conv to JHH. $154,900. Tracy, 443-8295038.

WYMAN COURT APTS. (BEECH AVE.) Effic from $570, 1 BD Apt. from $675, 2 BD from $775 HICKORY HEIGHTS APTS. (HICKORY AVE.) 2 BD units from $750 Shown by Appointment 410-764-7776

www.baltimoreanapartments.com

Lake Walker (MSL# BA7014995), 3BR, 2BA single-family house, open flr plan, newly renov’d, nr Belvedere Square and Towson. $239,900. Pam, 410-532-3055.

Share beautiful RH 2 blks north of Patterson Park, rm w/priv BA, short walk to JHMI shuttle. $600/mo (incl utils, Internet) + sec dep ($400). elizah81@gmail.com.

HOUSES FOR SALE

http://www.3507ncharlesinfo.com/

Open House - Sept. 12 - 3-7 pm!

Harborview, single-family house, nr all amenities, 15 mins to E Balto campus, 5 mins to Bayview, 20 mins to Homewood campus. $168,500. 443-604-2797.

Share safe place at JHMI w/medical students. happyhut4u@yahoo.com.

F wanted for nice, clean rms in quiet, residential Columbia neighborhood, no smoking/no pets, mins to Loyola College (Columbia), Rt 32/95/Rt 100. $590/mo incl utils and Internet. cjjave09@gmail.com.

Call Elena: 201-213-5354 See more online:

The Baltimorean Apartments - 410-889-4157

Hampden, totally renov’d 3BR, 2.5BA house w/screened porch, fenced yd, priv prkng, walk to Homewood/shops/restaurants/grocers/theater. $310,000. 919-607-5860 or 410-962-5417.

My Brest Friend nursing pillow, new, $25; Fisher-Price bouncer, $25; Graco carseat, $50; Safety First carseat and base, $50; HP06A and HP74A printer cartridges, $25/ ea; Kiddopotamus snuzzler, $6; JJcole Bundle Me, $10; baby bathtub, $5. Anitha, 612239-3672 or yerrabelli@gmail.com.

$309,750.00

www.brooksmanagementcompany.com

11

And we deliver!

410-327-7152 fax: 410-327-0862 2917 O’Donnell St.

Rent In Historic 1891 Elevator Secured Bldg.

Central to all Baltimore Johns Hopkins Locations!

Brand New Units: Only 4 left! $1250-$1400 2 BD 2 Full BA All with full size W/D, D/W, micro., carpet, CAC, Free off-street parking. 2300 N. Calvert St. 410 .764.7776 www.BrooksManagementCompany.com

Nikon, 12-24mm lens, mint cond, $800; Haier air conditioner w/remote, 12,000 BTUs, almost new, $100; queen airbed w/ Continued on page 10

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines: • One ad per person per week. A new request must be submitted for each issue.

• Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or

e-mail addresses.

• Submissions will be condensed at the editor’s discretion.

• Deadline is at noon Monday, one week prior to the edition in which the ad is to be run.

• Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.)

Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 410-343-3362.

12 THE GAZETTE • September 8, 2009 S E P T .

8

–

Calendar Wed.,

B L OO D D R I V Es Tues., Sept. 8, and Wed., Sept. 9, 7 a.m. to 7 p.m.

East Baltimore campus blood drive. Schedule an appointment online at www.hopkinsmedicine .org/jhhr/whatsnew/blood, e-mail johnshopkinsblooddrive@jhmi .edu or call 410-614-0913. Walkins welcome. For more information, e-mail wcartwr@jhmi.edu or call 410-735-4963. Turner Concourse. EB COLLOQUIA Thurs., Sept. 10, 3 p.m. “Old, Red and Dead Galaxies in a Lambda CDM Universe,” a Physics and Astronomy colloquium with Eric Bell, University of Michigan.

Schafler Auditorium, Bloomberg Center. HW

D I S C U S S I O N / TA L K S

“The 3Ds in Action: A System-Wide Approach to 21st Century Security,” a Conflict Management Program discussion with Louise Diamond, president, Global Systems Initiatives; Cynthia Irmer, U.S. Department of State; Lisa Schirch, director, 3D Security Initiative; and Susan Collin Marks (moderator), Search for Common Ground. For more information or to RSVP, contact 202-572-6294 or bgass@sfcg.org. Co-sponsored

by Search for Common Ground.

Kenney Auditorium, Nitze Building. SAIS

Tues., Sept. 8, 9 a.m.

Wed.,

Sept.

9, 12:30

p.m.

“Obama, Africom and the United States Security Policy Toward Africa,” an African Studies Program discussion with Daniel Volman, director, African Security Research Project. For more information, call 202-663-5676 or e-mail itolber1@jhu.edu. 736 Bernstein-Offit Building. SAIS Wed., Sept. 9, 12:30 p.m. “The

Obama Administration’s Policy Toward South Asia,” a South Asia Studies Program discussion with Robert Blake, assistant secretary for South and Central Asian Affairs, U.S. Department of State. For more information or to RSVP, e-mail southasia@jhu .edu. Kenney Auditorium, Nitze Building. SAIS Wed.,

Sept.

9, 12:30

p.m.

“The Current U.S.–China–Russia Strategic Triangle and Its Future Evolution,” a China Studies Program discussion with He Weibao, Ford Foundation and the Chinese Academy of Social Sciences. For more information, call 202-6635816 or e-mail zji@jhu.edu. 103 Rome Building. SAIS “Last Chance: The Middle East in the Balance,” a Middle East Studies Program discussion with author David Gardner. For more information, call 202-663-5649 or e-mail katarina@jhu.edu. 517 Nitze Building. SAIS

Wed., Sept. 9, 12:30 p.m.

Sept.

9, 6:45

p.m.

“Exploring the Potential Impact of Financial Sanctions on North Korea,” a U.S.–Korea Institute at SAIS discussion with John Park, Center for Conflict Analysis and Prevention, United States Institute of Peace. Co-sponsored by the Sejong Society of Washington DC. For information, call 202-663-5830 or e-mail nbaillis@jhu.edu. Rome Building Auditorium. SAIS Thurs., Sept. 10, noon. “Our Identities on a Map: Canadian and American Perceptions,” a Canadian Studies Program discussion with Jack Jedwab, executive director, Association for Canadian Studies, and Susan Hardwick, University of Oregon. For more information or to RSVP, call 202663-5714 or e-mail slee255@jhu .edu. Rome Building Auditorium.

SAIS

“Living in a Closed Country: Remembering Burma’s Saffron Revolution,” a Center for Public Health and Human Rights panel discussion with exiled Burmese Buddhist monks U Agga Nya Na, Cho Naing and U Pyi Nya Zaw Ta. (See related event under “Film/ Video.”) W1020 SPH. EB Fri., Sept. 11, noon.

E X H I B I T I O N S Sat., Sept. 12, 4 to 6 p.m.

Opening of the exhibition A View of the Parade: H. L. Mencken and American Magazines, documenting Mencken’s appearances in American magazines, from the George H. Thompson Collection of Henry Louis Mencken. Sponsored by the Friends of the Libraries. George Peabody Library. Peabody

F I L M / V I D EO Thurs., Sept. 10, 5 p.m. Screen-

ing of Burma VJ, a 2009 Sundance Award–winning film about the 2007 Saffron Revolution. A question-and-answer session follows, with exiled Burmese monks U Agga Nya Na, Cho Naing and U Pyi Nya Zaw Ta. (See related event under “Discussion/Talks.”)

Sponsored by the Center for Public Health and Human Rights.

E2014 SPH (Sommer Hall). EB

G RA N D ROU N D S

“Missing Data in Weight Loss Studies,” Biostatistics grand rounds with Lawrence Appel, SoM; Tom Louis, SPH; Lawrence Cheskin, SPH; and Stephen Gange, SPH. W2030 SPH. EB Sept.

11, 12:15

Wed.,

Sept.

9, 12:30

p.m.

Information session for the SAIS Conflict Management Program field trip to Kosovo, with P. Terrence Hopmann, director, Conflict Management Program. Open to the SAIS community only. For more information, call 202-6635745 or e-mail itlong@jhu.edu.

200 Rome Building. SAIS Thurs., Sept. 10, 5 p.m. Information session for the Conflict Management Program’s PeaceKidZ course. Open to SAIS community only. 408 Rome Building. SAIS

L E C TURE S

Carey Business School’s Dean’s Lecture Series—“Business Leadership for the Global Commons”

by Carolyn Woo, University of Notre Dame. For more information, e-mail carey.lectureseries@ jhu.edu. To register, go to carey.jhu .edu/deanslectures. (See “In Brief,” p. 2.) Mason Hall. HW Thurs., Sept. 10, 5:15 p.m.

“Generic Hybridity and Authorial Anxiety,” a German and Romance Languages and Literatures lecture

by Francois Rigolot, Princeton University. Co-sponsored by the Singleton Center for Premodern Studies. 101A Dell House. HW REA D I N G S Barnes & Noble Johns Hopkins

presents discussions and signings of new books. (See “In Brief,” p.

2.) HW •

•

Local author and 92Q radio personality LaDawn Black with her new book, Tease.

Wed., Sept. 9, 7 p.m.

Sat.,

Sept.

p.m.

“CRISP: The Chesapeake Regional Information System for our Patients,” Health Sciences Informatics grand rounds with Stephanie Reel, CIO and vice provost for IT, and David Horrocks, president, CRISP. Sponsored by SoM and SPH. W1214 SPH (Sheldon Hall). EB

12,

2

p.m.

Author Sung J. Woo and his debut novel, Everything Asian.

S E M I N AR S

“Meiotic Prophase Arrest and Resumption Mouse Oocytes: A Tale of Two Pathways,” a Carnegie Institution Embryology seminar with Rachael Norris, University of Connecticut Health Center. Rose Auditorium, 3520 San Martin Drive. HW

Tues., Sept. 8, 12:15 p.m.

“On the Experiential, Symbolic and Structural Forms of HIV/AIDS Related Stigma: An Exploratory Study Among Multiple Youth Populations in Delhi, India,” a Health, Behavior and Society thesis defense seminar with Devaki Nambiar. 744 Hampton House. EB

Tues.,

Sept.

8,

Adults,” a Mental Health seminar with Adam Spira, SPH. B14B Hampton House. EB “Male Circumcision: Research on Implications for Men and Women and Programmatic Challenges in Rakai, Uganda,” a Population, Family and Reproductive Health seminar with Maria Wawer, SPH, and Ron Gray, SPH. W2030 SPH. EB Wed., Sept. 9, 12:15 p.m.

Wed., Sept. 9, 3 p.m. “Probing Polymer Photovoltaics,” a Materials Science and Engineering seminar with Patricia McGuiggan, WSE. 110 Maryland. HW

“Religion and Science in Early Modern European Literature,” a three-part seminar series with Joachim Kupper, Freie Universitat Berlin. Sponsored by German and Romance Languages and Literatures, the Singleton Center for the Study of Premodern Europe, the Jewish Studies Program and Evolution, Cognition and Culture. 101A Dell House. HW

Wed., Sept. 9, 5:15 p.m.

“Looking Into TB: What Can We Learn?” a Molecular Microbiology and Immunology/Infectious Diseases seminar with Joanne Flynn, University of Pittsburgh School of Medicine. W2030 SPH. EB

Thurs., Sept. 10, noon.

Thurs., Sept. 10, 5 to 6:30 p.m.

Tues., Sept. 8, 1 p.m.

Wed., Sept. 9, 3:45 p.m.

Fri.,

I N FOR M AT I O N SESSIONS

1 4

4:30

p.m.

“Improving Machine Translation

by Propagating Uncertainty,” a Center for Language and Speech Processing seminar with Chris Dyer, University of Maryland. B17 CSEB. HW “Adverse Outcomes of Poor Sleep in Older

Wed., Sept. 9, noon.

Thurs., Sept. 10, noon. “Influenza A Virus Assembly and the M2 Protein: New Tricks for an Old Dog,” a Cell Biology seminar with Andrew Pekosz, SPH. Suite 2-200, 1830 Bldg. EB Thurs., Sept. 10, 1 p.m. “ITCH,”

a Neuroscience research seminar with Robert Lamotte, Yale University School of Medicine. West Lecture Hall, WBSB. EB

Thurs., Sept. 10, 4 p.m. “Absorption Times for Markov Chains,” an Applied Mathematics and Statistics seminar with Jim Fill, WSE. 304 Whitehead. HW Thurs., Sept. 10, 4 p.m. “Structure Induction for Dextrous Motion,” an Electrical and Computer Engineering seminar with Balakrishnan Varadarajan, WSE. 110 Maryland. HW

lar Biology seminar with Rachel Green, SoM. W2030 SPH. EB The David Bodian Seminar—“WholeCell Recordings in Thalamus Reveal How Retinal Gamma Oscillations Convey Additional Visual Information” with Friedrich Sommer, University of California, Berkeley. Sponsored by the Zanvyl Krieger Mind/Brain Institute. 338 Krieger. HW

Mon., Sept. 14, 4 p.m.

“ ‘We Unhappy Few’: In Search of Jewish Culture in Postwar Germany,” a History seminar with Michael Brenner, Brandeis University.

Co-sponsored by German and Romance Languages and Literatures. 102B Dell House. HW

Mon., Sept. 14, 4 p.m.

SPECIAL EVENTS Wed., Sept. 9, 3:30 to 6 p.m.

Tribute to Edyth Schoenrich on her 90th birthday—a symposium at 3:30 p.m. in E2014 SPH, followed by a reception at 5 p.m. in E2030 SPH. Sponsored by the Office of External Affairs. EB Fri., Sept. 11, through Tues., Sept. 15. Events honoring the

installation of university president Ronald J. Daniels. (See article, p.

1.) Various locations.

Fri., Sept. 11, 11 a.m. “Back to School” inventory sale of SAIS clothing, gifts and more. Lobby, Nitze Building. SAIS Sat., Sept. 12, 3 to 6 p.m.

Convergence, neighborhood block party for Hopkins students and the Charles Village community.

Booths, food, entertainment, games and information tables. 3200 block St. Paul St. HW W OR K S HO P S The Center for Educational Resources presents WebCT workshops. Garrett Room, MSE Library. HW

•

With WebCT,” introduction and overview of the application’s capabilities. Open to faculty only.

Mon., Sept. 14, 12:10 p.m.

“Injury and Violence Prevention: Innovative Community Research and Practice,” a Graduate Seminar in Injury Research and Policy with Kira McGroarty, CARES; Eileen McDonald, SPH; and Shannon Frattaroli, SPH. Sponsored by Health Policy and Management.

208 Hampton House. EB Mon., Sept. 14, 12:15 p.m.

“Beyond the Embryo: Evolution of Regeneration and Asexual Reproduction in Annelids and Acoels,” a Carnegie Institution Embryology seminar with Alexandra Bely, University of Maryland, College Park. Rose Auditorium, 3520 San Martin Drive. HW Mon., Sept. 14, 3 p.m. “Enzymatic Cellulose Degradation by Thermobifida fusca Cel5a,” a Biophysics seminar with Brian Barr, Loyola College. 111 Mergenthaler. HW

“KakeyaNikodym Averages and Lp Norms of Eigenfunctions,” a Mathematics seminar with Chris Sogge, KSAS. 302 Krieger. HW

Mon., Sept. 14, 3 p.m.

Mon., Sept. 14, 4 p.m. “Quality Control During Protein Synthesis,” a Biochemistry and Molecu-

Tues., Sept. 8, 10 a.m. to noon. “Getting Started

•

Wed., Sept. 9, 10 a.m.

•

Thurs., Sept. 10, 10 a.m.

“WebCT: Content and Communication.”

“WebCT: Assessing Student Knowledge and Managing Students and Grades.”

Thurs., Sept. 10, 9 a.m. to 4 p.m. “Scientific Presentations,” a

JHMI Professional Development workshop for JHMI faculty and postdoctoral and clinical fellows.

Cost is $650 for faculty and $325 for others. Workshop includes follow-up practice session with video recording. For information or to register, call 410-502-2804 or e-mail jhmipdo@jhmi.edu.

Mountcastle Auditorium. EB

Calendar

Key

(Events are free and open to the public except where indicated.)

CSEB Computational Science and

EB HW PCTB SoM SoN SPH WBSB

Engineering Building East Baltimore Homewood Preclinical Teaching Building

School of Medicine School of Nursing School of Public Health Wood Basic Science Building