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February 14, 2011

The newspaper of The Johns Hopkins University

R E S E A R C H

S T U D E N T

Volume 40 No. 22 L I F E

Something in Commons

E2SHI: New acronym, big ambitions By Phil Sneiderman

Homewood

Continued on page 4

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

rawing on faculty expertise in environmental science and engineering, public health and other areas, The Johns Hopkins University has launched its Environment, Energy, Sustainability and Health Institute to promote research and Environment, education in topics ranging from green green energy energy practices to climate change among topics and related health issues. “This kind of of focus for research right now new institute is distributed all across the university,” said Benjamin Hobbs, director of the institute. “Because of this, it’s been a challenge to put together interdisciplinary teams to study these topics, and our profile on these issues is not as high as it should be. The institute’s goal is to encourage these research and education partnerships and to promote Johns Hopkins as a world leader in these areas.” The creation of this institute, called E2SHI for short (and pronounced ehshee), was a key recommendation in the university’s Implementation Plan for Advancing Sustainability and Climate Stewardship. This 2010 plan was drafted to address some of the goals set by a task force assembled by then university President William R. Brody. The task force completed its recommendations and presented them to Brody’s successor, President Ronald J. Daniels, who enthusiastically endorsed them. The institute began taking shape last year, when the Provost’s Office contributed startup funds. Then, this past autumn, the deans of the Whiting School of Engineering, Krieger School of Arts and Sciences and Bloomberg School of Public Health approved E2SHI’s charter and agreed to provide financial support. Hobbs, the Theodore M. and Kay W. Schad Professor in Environmental Management in the Whiting School, was

Jen Al Naber and Karen Chan make Valentine’s Day candy as part of the Charles Commons Connections event held Thursday night. Looking on are faculty fellow Mike Yassa and, at right, Yassa’s wife, Manuella, and daughter, Isabella.

Strictly social: Students and faculty connect over dinners, trips and more By Greg Rienzi

The Gazette

ike Yassa knows brain science, but caramel apples leave him in sticky knots. Yassa, an assistant professor in the Department of Psychological and Brain Sciences, wrestled with the treat at the Charles Commons Connections welcome back event on Feb. 1, his first official appearance as the Home-

wood residence hall’s new faculty in residence. “My caramel apple never dried,” Yassa recently lamented. To make matters worse, the gooey confection later came into contact with random toys belonging to his 10-month-old daughter, Isabella. Continued on page 7

O U T R E A C H

Free online ordering of home test kits for STIs proves effective with teens, young adults www.iwantthekit.org site found to encourage both screening and treatment B y D av i d M a r c h

Johns Hopkins Medicine

nfectious disease experts at Johns Hopkins say that new research clearly shows that screening teens and young adults for

In Brief

CAREER Award; blood drives; BME team’s business plan success; two author readings

sexually transmitted infections may best be achieved by making free, confidential homekit testing available over the Internet. From a public health standpoint, the project is a clear winner, the experts say. Reporting in the February issue of Sexually Transmitted Diseases, the Johns Hopkins team describes the success of the program started in Baltimore in 2004 that lets men and women in their teens or 20s order over the Internet home-testing kits for the most common STIs. The Johns Hopkins group designed the www.iwantthekit.org website, accessible now

in several states, to track new and recurrent infections by providing private, confidential testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. The project also facilitates treatment for those who test positive. “Our results are repeatedly showing us that we have to go online if we want young people to be screened for sexually transmitted infections, especially young people in harder-to-reach, urban-poor minority Continued on page 5

10 Job Opportunities 10 Notices Turnbull Memorial Poetry Lecture; NASA Lunar Science Institute; HSO plays Copland 11 Classifieds C a l e nd a r

2 THE GAZETTE • February 14, 2011 PS-2011 JHU Gazette 1-31.qxd

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Camp Open House Saturday, April 9 • 11am – 1pm

ParkCamps • Explorer and Pioneer Camps for Young Children • Arts and Science Camps • Young Filmmakers’ Workshop • Sports Camp • Beyond Park Day Trips • Leadership Camp • Project Boost

Sharon Gerecht of WSE receives CAREER award

haron Gerecht, an assistant professor in the Whiting School’s Department of Chemical and Biomolecular Engineering, is the recipient of a Faculty Early Career Development Award from the National Science Foundation. The CAREER award, given to faculty members at the beginning of their academic careers, is one of NSF’s most competitive awards and emphasizes high-quality research and novel education initiatives. Gerecht’s CAREER project is focused on an interdisciplinary investigation of functional interactions between hypoxic pathways and matrix-driven cues that are essential for vascular morphogenesis and network assembly. Her proposed research includes the study and basic understanding of vascular network assembly and promises both to uncover the mechanisms underlying vasculature growth and to elucidate the interfaces involved in vascular development signaling pathways for vascular regeneration applications.

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uring the winter months, the Greater Chesapeake & Potomac Blood Services Region of the American Red Cross often sees a significant decline in blood donations, resulting in a dangerously low blood supply. To help support the need, Johns Hopkins has three blood drives scheduled in the coming weeks. A Homewood campus drive will be held from 7:30 a.m. to 5:45 p.m. on Tuesday, Feb. 15, and from 10:30 a.m. to 5:30 p.m. on Wednesday, Feb. 16, in the Glass Pavilion. Bayview Medical Center’s will be held from 7:30 a.m. to 5 p.m. from Monday, Feb. 21, through Wednesday, Feb. 23, in the Francis X. Knott Conference Center. A drive is planned on the Mount Washington campus from 8 a.m. to 2 p.m. on Thursday, Feb. 24, in the Fitness Center. For details, go to www.hopkinsworklife .org/community/blood_drive_locations .html.

BME grad student team scores in business plan competition

team of Johns Hopkins biomedical engineering graduate students tied for first place in the 2011 Georgia Bowl Business Plan Competition, hosted Feb. 4 and 5 by Kennesaw State University. Team members presented their business plan for TheraCord, a system that the students developed to improve the process of umbilical cord blood collection. Stem cells preserved from cord blood after live births can be used in the treatment of diseases such as leukemia and lymphoma.

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller Photography Homewood Photography A d v e rt i s i n g The Gazelle Group B u s i n e ss Dianne MacLeod C i r c u l at i o n Lynette Floyd Webmaster Tim Windsor

The Johns Hopkins team members— James Waring, Elias Bitar, Chris Chiang, Matthew Means and Sean Monagle—are enrolled in a yearlong master’s degree program offered through the university’s Center for Bioengineering Innovation & Design. The program helps students learn to develop biomedical devices and to move these projects into the marketplace. For the TheraCord project, the team’s clinical sponsor is Edith Gurewitsch, an associate professor of gynecology and obstetrics in the Johns Hopkins School of Medicine. The student inventors, who are continuing to test and refine their system, expect to enter their project in other college business plan competitions in the coming months.

Authors Jessica Anya Blau, Paula Bomer to read at B&N

wo critically acclaimed authors come to Barnes & Noble Johns Hopkins this Thursday, Feb. 17, to read from their latest novels, both of which are tales of unconventional families. Jessica Anya Blau, who received her M.F.A. in fiction from the Writing Seminars at Johns Hopkins, is the author of Drinking Closer to Home, in which three grown children come together in the wake of their mother’s heart attack. Blau’s first novel, The Summer of Naked Swim Parties, was selected as a best summer reading book by the Today show, The New York Post and New York Magazine. Paula Bomer is the author of Baby and Other Stories, which O Magazine put as No. 1 in its “Titles to Pick Up Now” list, calling it a “brilliant, brutally raw debut collection.”

Discounted tickets for shows at Hippodrome now available

t may be too late to save on special rates for Jersey Boys, but discounted tickets for other crowd-pleasing shows coming soon to the Hippodrome—Les Miserables, Shrek and West Side Story—are now available to Johns Hopkins employees through the Office of Work, Life and Engagement. For a full list of shows, along with deadlines and how to purchase the tickets through Ticketmaster, go to www.hopkinsworklife .org/financial/hippodrome.html. If purchasing tickets after the purchase deadline, call Megan Miley at 443-703-2401.

Johns Hopkins Bayview wins national diversity award

ohns Hopkins Bayview Medical Center is one of 25 U.S. organizations to receive a 2011 Diversity Council Honors Award. The award recognizes the outstanding contributions of councils that lead diversity processes in organizations and demonstrate results in the workforce, workplace and marketplace. Bayview will accept the award at an April ceremony in Atlanta.

Contributing Writers Applied Physics Laboratory Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg, Patrick Ercolano Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Vanessa McMains, Ekaterina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Government, Community and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: gazette@jhu.edu Classifieds e-mail: gazads@jhu.edu On the Web: gazette.jhu.edu Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 410343-3362 or gazellegrp@comcast.net.

February 14, 2011 • THE GAZETTE

JHU launches certificate in biotechnology education B y J a m e s C a m pb e l l

School of Education

his summer, The Johns Hopkins University will begin offering a unique graduate certificate in the field of bioscience education to address a national shortage of teachers in the fields of science, technology, engineering and math, often referred to as STEM. The new 20-credit graduate certificate in biotechnology education was created through a partnership between Johns Hopkins’ schools of Education and Arts and Sciences to address the fact that, as President Barack Obama said in his Jan. 25 State of the Union address, “the quality of our math and science education lags behind many other nations.” The president added, “Over the next 10 years, with so many baby boomers retiring from our classrooms, we want to prepare 100,000 new teachers in the fields of science and technology and engineering and math.”

With instruction by faculty from both the Krieger School of Arts and Sciences and the School of Education, students in the certificate program will develop ways to teach bioscience effectively in their middle and high school classrooms. Patrick Cummings, director of the Center for Biotechnology Education at Johns Hopkins and program director of the university’s Biotechnology program, said that there is no other program in the state that provides biotechnology training integrated with educational pedagogy. “Maryland has the fifth-largest biotechnology sector in the nation, [and] that requires a trained workforce,” Cummings said. “We want to develop the pipeline that begins in middle and high schools, where students first learn about bioscience.” Carolyn Parker, assistant professor in the School of Education’s Department of Teacher Preparation, said, “The certificate is designed to emphasize inquiry-oriented approaches and integrate technology into

bioscience. By integrating science content with pedagogy, this certificate creates unique new professional development opportunities for secondary science teachers interested in the biosciences.” Students can proceed through the program at their own pace, although most can expect to complete it within 15 months. Most courses will be offered in traditional classrooms or online, and students can choose either option as they proceed through the program. All participants are required to attend Johns Hopkins for a hands-on lab course residency, which will take place during the summer semester. Scholarship money is available from a gift provided by Becton Dickinson, which, through its Diagnostic Systems unit based in Sparks, Md., has joined Johns Hopkins as a partner in this effort. A leading global medical technology company that develops, manufactures and sells medical devices, instrument systems and reagents, Becton Dickinson is donating scientific equipment,

the expertise of its researchers and other support to the project. According to Cummings, the company is involved as part of its core purpose of helping all people live healthy lives. “BD believes that upgrading the life sciences skills of our teachers and their students is critical to its purpose and encourages other life sciences companies in Maryland to join us in this effort,” Cummings said. As part of the curriculum, teachers enrolled in the certificate program will have hands-on training in applied life sciences and diagnostic applications at the Becton Dickinson campus in Sparks, where some of the company’s scientists will serve as tutors. For more information about the certificate or how to apply, contact the School of Education at 877-JHU-SOE1 or soe.info@ jhu.edu; to participate in an online information session on March 1, go to www .biotechnology.jhu.edu/includes/rightcol_ events_news?ContentID=2950.

Safety checklist use yields 10 percent drop in hospital deaths By Stephanie Desmon

Johns Hopkins Medicine

Johns Hopkins–led safety checklist program that virtually eliminated bloodstream infections in hospital intensive care units throughout Michigan appears to have also reduced deaths by 10 percent, a new study suggests. Although prior research showed a major reduction in central line–related bloodstream infections at hospitals using the checklist, the new study is the first to show that its use directly lowered mortality. “We knew that when we applied safety science principles to the delivery of health care, we would dramatically reduce infections in intensive care units, and now we know we are also saving lives,” said Peter J. Pronovost, a professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine and leader of the study published in BMJ, the British medical journal. “Thousands of people are believed to have survived because of this effort to reduce bloodstream infections.” Pronovost’s previous research has shown that coupling a cockpit-style infection control checklist he developed with a work environment that

encourages nurses to speak up if safety rules aren’t followed reduced ICU central line bloodstream infections to nearly zero at The Johns Hopkins Hospital and at hospitals throughout the states of Michigan and Rhode Island. Experts say that an estimated 80,000 patients a year with central lines get infected, some 31,000 die—nearly as many as die from breast cancer annually—and the cost of treating them may be as high as $3 billion nationally. For the new study, Pronovost and his team, using Medicare claims data, studied hospital mortality of patients admitted to ICUs in Michigan before, during and after what is known as the Keystone ICU Project, which features the checklist. They compared the Michigan information to similar data from 11 surrounding states. While data from both Michigan and the other states showed a reduction in hospital deaths of elderly patients admitted to ICUs over the five-year period from October 2001 to December 2006, the patients in Michigan were significantly more likely to survive a hospital stay during and after the Keystone project.. These findings cannot definitively attribute the mortality reduction to the Keystone project, Pronovost says, but no other known large-scale initiatives were uniquely introduced across Michigan during the study period. “This is perhaps the only large-scale

study to suggest a significant reduction in mortality from a quality-improvement initiative,” Pronovost said. The Keystone ICU Project, developed at Johns Hopkins, includes a much-heralded

Related websites Peter Pronovost:

www.hopkinsmedicine.org/ anesthesiology_critical_care_ medicine_research/experts/ research_faculty/bios/pronovost .html

Center for Innovation in Quality Patient Care:

www.hopkinsmedicine.org/ innovation_quality_patient_care

checklist for doctors and nurses to follow when placing a central line catheter, highlighting five cautionary and basic steps from hand washing to avoiding placement in the groin area, where infection rates are higher. Along with the checklist, the program promotes a “culture of safety” that comprises safety science education, training in ways to identify potential safety problems, development of evidence-based solutions

and measurement of improvements. The program also empowers all caregivers, no matter how senior or junior, to question each other and stop procedures if safety is compromised. Central lines are thin plastic tubes used regularly for patients in ICUs to administer medication or fluids, obtain blood for tests and directly gauge cardiovascular measurements such as central venous blood pressure. The tubes are easily contaminated. In 2009, Health and Human Services Secretary Kathleen Sebelius called for a 50 percent reduction in catheter-related infections nationwide by 2012. To that end, in partnership with a branch of the American Hospital Association and the Michigan Hospital Association, the Johns Hopkins model is being rolled out state by state across the country. Forty states have launched the program, and preliminary data from some of the early adopters is very encouraging, Pronovost says. The original Keystone project was funded by HHS’s Agency for Healthcare Research and Quality. Other Johns Hopkins researchers involved in the research are Allison Lipitz-Snyderman, Donald Steinwachs, Dale M. Needham, Elizabeth Colantuoni and Laura L. Morlock.

R E C O G N I T I O N

Johns Hopkins’ Andrew Ewald honored by anatomy society By Audrey Huang

Johns Hopkins Medicine

ndrew Ewald, who studies how cells build organs and how these same cellular processes can contribute to breast cancer metastasis, will receive the American Association of Anatomists’ 2011 Morphological Sciences Award for his “outstanding contributions to the field of epithelial morphogenesis.” He will present an award lecture at the Annual Meeting of the American Association of Anatomists on Sunday, April 10, in Washington, D.C. “This is a real honor,” said Ewald, an assistant professor of cell biology at Johns Hopkins and a member of both the Johns Hopkins Institute for Basic Biomedical Sciences’ Center for Cell Dynamics and the Sidney Kimmel Comprehensive Cancer Center’s Breast Cancer Program. “This award serves

to recognize the work I have done in the past but also serves as a great encouragement and validation that we are headed in the right direction. The work recognized in this award could never have been accomplished without the mentoring I received and collaborations I developed during my training in the Fraser Lab at Caltech and the Werb Lab at UCSF, and now the terrific work of my own students and fellows.” The Ewald Lab uses advanced time-lapse microscopy and molecular genetics to study the normal development of tissues, with a primary focus on the mammary gland. The team is trying to understand the cellular and molecular processes that enable normal epithelial cells to progress to invasive and eventually metastatic breast cancer. “Andy’s elegant studies provide insights to important developmental processes and have clear clinical implications,” said Peter Devreotes, the Isaac Morris and Lucille Elizabeth Hay Professor and director of

Cell Biology at Johns Hopkins. “And Andy clearly will be a major force going forward with his dedication to mammary gland morphogenesis and breast cancer research.” “I think the impact of Andy’s work is going to be really enormous,” said Denise Montell, director of the IBBS Center for Cell Dynamics. “He is right at the interface of basic and translational research. This is a really exciting opportunity to build a bridge between the two, and Andy is the perfect person to do this.” Ewald joined the faculty at the Johns Hopkins University School of Medicine in 2008 following postdoctoral work with Zena Werb in mammary biology and cancer at the University of California, San Francisco. He received his bachelor’s degree in physics with honors from Haverford College in 1997 and his doctorate in biochemistry and molecular biophysics in 2003 for work done with Scott Fraser at the California Institute of Technology.

Related websites Andrew Ewald:

www.hopkinsmedicine.org/cellbio/ dept/EwaldProfile.html

www.hopkinsmedicine.org/ institute_basic_biomedical_ sciences/about_us/scientists/ andy_ewald.html

www.hopkinsmedicine.org/ institute_basic_biomedical_ sciences/news_events/articles_ and_stories/cancer_disease/2009_ 03_biological_art_organs_.html

Center for Cell Dynamics:

www.hopkinsmedicine.org/ institute_basic_biomedical_ sciences/research/research_ centers/cell_dynamics

4 THE GAZETTE • February 14, 2011

‘.jpg’ for the mind: How the brain compresses visual information By Lisa De Nike

Homewood

ost of us are familiar with the idea of image compression in computers. File extensions such as “.jpg” or “.png” signify that millions of pixel values have been compressed into a more-efficient format, reducing file size by a factor of 10 or more with little or no apparent change in image quality. The full set of original pixel values would occupy too much space in computer memory and take too long to transmit across networks. The brain is faced with a similar problem. The images captured by light-sensitive cells in the eye’s retina are on the order of a megapixel. The brain does not have the transmission or memory capacity to deal with a lifetime of megapixel images. Instead, it must select only the most vital information for understanding the visual world. In the Feb. 10 online issue of Current Biology, a Johns Hopkins team led by neu-

E2SHI Continued from page 1 selected as the institute’s first director. Cindy Parker, an assistant professor with dual appointments in the Bloomberg School’s Department of Environmental Health Sciences and the Krieger School’s Department of Earth and Planetary Sciences, was named associate director. In recent weeks, activity at the institute has accelerated. • The institute has launched an internal seed grant program, offering up to $25,000 for 12 months of work. These funds will be

roscientists Ed Connor and Kechen Zhang describes what appears to be the next step in understanding how the brain compresses visual information down to the essentials. The researchers found that cells in area “V4,” a midlevel stage in the primate brain’s object vision pathway, are highly selective for image regions containing acute curvature. Experiments by doctoral student Eric Carlson showed that V4 cells are very responsive to sharply curved or angled edges, and much less responsive to flat edges or shallow curves. To understand how selectivity for acute curvature might help with compression of visual information, co-author Russell Rasquinha (now at the University of Toronto) created a computer model of hundreds of V4-like cells, training them on thousands of natural object images. After training, each image evoked responses from a large proportion of the virtual V4 cells—the opposite of a compressed format. And, somewhat surprisingly, these virtual V4 cells responded mostly to flat edges and shallow curvatures,

just the opposite of what was observed for real V4 cells. The results were quite different when the model was trained to limit the number of virtual V4 cells responding to each image. As this limit on responsive cells was tightened, the selectivity of the cells shifted from shallow to acute curvature. The tightest limit produced an eightfold decrease in the number of cells responding to each image, comparable to the file size reduction achieved by compressing photographs into the .jpg format. At this level, the computer model produced the same strong bias toward high curvature observed in the real V4 cells. Why would focusing on acute curvature regions produce such savings? Because, as the group’s analyses showed, high-curvature regions are relatively rare in natural objects, compared to flat and shallow curvature. Responding to rare features rather than common features is automatically economical. Despite the fact that they are relatively rare, high-curvature regions are very useful

for distinguishing and recognizing objects, said Connor, a professor in the Solomon H. Snyder Department of Neuroscience in the School of Medicine and director of the Zanvyl Krieger Mind/Brain Institute. “Psychological experiments have shown that subjects can still recognize line drawings of objects when flat edges are erased. But erasing angles and other regions of high curvature makes recognition difficult,” he said. Brain mechanisms such as the V4 coding scheme described by Connor and colleagues help explain why we are all visual geniuses. “Computers can beat us at math and chess,” Connor said, “but they can’t match our ability to distinguish, recognize, understand, remember and manipulate the objects that make up our world.” This core human ability depends in part on condensing visual information to a tractable level. For now, at least, the “.brain” format seems to be the best compression algorithm around. For more about the Mind/Brain Institute, go to krieger.jhu.edu/mbi.

awarded to launch institute-related research projects that involve cross-divisional collaborations and that are likely to receive longer-term funding from outside sources. Seed grant applications are being accepted through Feb. 28. • On its new website (e2shi.jhu.edu), the institute is spreading the word about grant opportunities related to air quality, energy and environmental sustainability, with funding available through the National Science Foundation, the Environmental Protection Agency and other external sources. • The institute has set up a fellowship program to support graduate students who will engage in multidisciplinary research on the environment, energy supply and use, economic and ecological sustainability, or

projects that have a public health link to these topics. Fellowship applications are due Feb. 21. • Plans are under way for a kickoff event that will feature a welcome statement from President Daniels and a symposium on institute-related topics. The event is slated for the afternoon of April 20, during Earth Week, at a location that will be determined soon. Hobbs said that he is “immensely pleased by the interest shown in our startup and fellowship programs as the institute gets rolling. People across the university are talking about how they might work together on research in science, engineering and policy that will be critical to helping Johns Hopkins, Maryland and, indeed, the world on the path to sustainability.” Although the institute’s startup funding is coming from the Whiting, Krieger and Bloomberg schools and the central administration, the goal is to become financially self-sufficient by obtaining grants, contracts and donations. Another goal is to establish ties to other Johns Hopkins divisions, including the Applied Physics Laboratory, School of Medicine, School of Advanced International Studies and Carey Business School. APL, SAIS and the Carey School already have representatives on E2SHI’s executive committee. Initially, the Whiting School is hosting the Environment, Energy, Sustainability and Health Institute. “This is an area in which I believe Johns Hopkins can have a major impact,” said Nick Jones, the Benjamin T. Rome Dean of the school. “The institute provides the structure necessary to create highly complementary cross-divisional collaborations,

leverage existing expertise and attract new funding and research partners as we systematically address issues of global importance.” Institute director Hobbs said that the organization follows the general model established by the university’s Homewoodbased Institute for NanoBioTechnology. The INBT, launched in 2006, is largely a “virtual” organization that has limited facilities of its own but promotes interdisciplinary projects involving more than 200 affiliated researchers in five Johns Hopkins divisions. Since its creation, INBT has attracted more than $25 million in interdisciplinary research funding. In addition to fostering Johns Hopkins research in its own specialized topics, the Environment, Energy, Sustainability and Health Institute will seek to enhance and coordinate environmental curricula at the undergraduate and graduate levels. Yet another aim is to develop partnerships with the business sector, government agencies, environmental groups and Baltimore community organizations. The institute also will work with the university’s Office of Sustainability in connection with ongoing carbon reduction efforts. “Other universities have established environmental institutes,” Hobbs said. “However, we have unique capabilities—especially in the health, space technology, green energy and policy areas—that will enable Johns Hopkins to contribute in ways no one else can. We are enthused about the quality of people and research already happening here, and we believe that working together will enable utterly remarkable things to happen.” G For more information on grant applications and the upcoming kickoff event, go to e2shi.jhu.edu.

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Open House Saturday Noon to 4pm

Ben Hobbs, seen in this file photo in front of the Homewood power plant, has been named inaugural director of the Environment, Energy, Sustainability and Health Institute.

February 14, 2011 • THE GAZETTE

Peabody Chamber Opera remembers the ’50s at Theatre Project Hoiby and Bernstein works show contrasting sides of a simmering decade By Richard Selden

Peabody Institute

eabody Chamber Opera will present Remember the Fifties—a double bill of one-act operas about the decade of Eisenhower, Burma Shave and I Love Lucy— at Theatre Project, 45 W. Preston St., from Feb. 24 to 27. The two works are Lee Hoiby’s This Is the Rill Speaking of 1991 and Leonard Bernstein’s Trouble in Tahiti of 1952. This Is the Rill Speaking, with a libretto by Mark Shulgasser, is based on the 1965 play

Kits Continued from page 1 groups,” said infectious disease specialist Charlotte Gaydos, senior study investigator. The website, she said, routinely gets 100,000 monthly hits. As of Jan. 1, some 3,500 young people, half under the age of 23 and many from lowincome households, have requested their free test kit, some more than once. Initially, kits were also offered at local pharmacies and in public health clinics, but nine out of 10 who used the kit ordered it online. “The Internet is by far the most popular means of getting tested among this sexually active group, and at a time when they are most at risk of becoming infected.” The program, which Gaydos says “could readily be introduced to all 50 states and overseas,” has grown increasingly popular since its debut, when only tests for women were offered. Kits for both sexes can be ordered in Maryland, the District of Columbia, West Virginia, parts of Illinois, Denver and Philadelphia. Gaydos and her team expect an influx of orders after federally funded newspaper and radio ads to promote the website appear in Washington, D.C., Maryland and Philadelphia during April, which is national STI Awareness Month. Each kit comes with instructions, a unique identification number and a prepaid return envelope to mail self-collected vaginal, penile or rectal swabs in sealed test tubes to Gaydos’ lab at Johns Hopkins. The kits are sent in plain brown envelopes and contain a detailed questionnaire that allows researchers to gather information about who used the kit and why. Within two weeks of sending the test to the lab, people can call a toll-free number, provide their ID number and a secret password chosen when they order, and get their test results. So far, 444 women and girls, some as young

of the same name by Hot l Baltimore author Lanford Wilson. A rill being a small ditch through which water flows, the opera, set in rural America, is a series of vignettes about a family of four: mother, father, teenage daughter and teenage son. The musical and dramatic contrast with Trouble in Tahiti, which brings the audience into the unhappy lives of an affluent suburban couple, could not be greater. The opera was composed by Bernstein just a few years before West Side Story, and his Broadway style is immediately recognizable. The couple’s failure to communicate is portrayed in upbeat, often hilarious, music, including commentary by the “Tahiti trio,” the sort of Greek chorus one might find in a detergent commercial. “The time period is a precursor to the period of Mad Men,” said Peabody faculty member Jennifer Blades, stage director for

the production, who has twice played the female lead in Trouble in Tahiti in area productions. “Everything simmered in the ’50s, then exploded in the 1960s.” Eight student singers will perform. Four of the six in This Is the Rill Speaking play multiple roles. Katelyn Jackman, a Master of Music candidate studying with Phyllis Bryn-Julson, appears in both shows, playing Mother and Allison in This Is the Rill Speaking and the female lead, Dinah, in Trouble in Tahiti. Sam, the male lead in Trouble in Tahiti, is played by Peter Tomaszewski, a Graduate Performance Diploma candidate studying with John Shirley-Quirk. The other students in the cast are David Diehl, Joseph Harrell, Sonya Knussen, Marie Marquis, Stephanie Miller and Jorge Ramirez-Sanchez. Two students in Peabody’s graduate conducting program will lead the pit orchestra.

Lee Mills will conduct This Is the Rill Speaking and Blair Skinner, Trouble in Tahiti. The singers and conductors were coached by Peabody Opera’s music director, JoAnn Kulesza. Set designer Thom Bumblauskas has created montages of 1950s advertisements as backdrops. The lighting designer is Doug Nelson, resident lighting designer and production manager for Peabody Opera since 1985. Performances are at 7:30 p.m. on Thursday, Friday and Saturday and at 3 p.m. on Sunday. Tickets are $25, $15 for seniors and $10 for students with ID. The audience is invited to meet the performers at a free reception sponsored by the Friends of Peabody after the Sunday performance. To purchase tickets, go to www .missiontix.com or call Theatre Project at 410-752-8558.

as 15, and 192 men and boys, for whom screening started in 2006, have tested positive for one or more bacterial or protozoon infections. All but four women and one man who tested positive sought subsequent treatment. For those who test positive, referrals are offered to nearby public health clinics. “Using the Web is a very safe, private, secure and practical forum for young people to deal with sexually transmitted infections,” said Gaydos, a professor at the Johns Hopkins University School of Medicine. “People can order a kit any time of day, without having to leave school or work, and can get tested with a level of anonymity that minimizes any fear of stigma or self-conscious feelings that may come with talking to a parent, school counselor or health professional about a sex-related health problem.” The study results focused on women and showed that over a five-year period in Maryland, the iwantthekit.org screening program detected more cases of chlamydia infection among young females than regular screening programs available at traditional family-planning clinics. Infection rates for chlamydia, which if left untreated can lead to so-called pelvic inflammatory disease and infertility in women, ranged from 3.3 percent to 5.5 percent in local clinics to 4.4 percent to 15.2 percent with the Internet service, statistics that Gaydos says demonstrate the online program’s potentially greater reach. “A lot of these young women are poor, with little to no health insurance, and seldom see a physician or undergo a health checkup, so this is a free means of getting them tested and cared for quickly and before they potentially pass the infection on to someone else,” said Gaydos, who notes that at least four in five people infected show no symptoms, so the chances of unknowingly spreading infections are high. Gaydos says that the program, funded by a grant from the Centers for Disease Control and Prevention, is also highly effective in promoting retesting, noting that 17 percent of users feel comfortable enough with the

system to use it again; almost half have been screened multiple times, even if they tested negative at first. Gaydos stresses that people who have been infected once are 10 percent more likely to get reinfected. This is why, she says, the CDC recommends that all sexually active women age 25 or younger get screened for chlamydia at least once a year, with women who have tested positive getting retested within three months of their initial infection. Gaydos says that 6 percent of repeat kit users have tested positive before, while her other research has shown a 25 percent chlamydia reinfection rate among young women in the Baltimore area. The need for repeat testing applies equally to sexually active males, says Gaydos, whose team reported in December in Sexually Transmitted Diseases that among 501 tested, some as young as 14, many did not practice safe sex. Only 13 percent used condoms. Even more were at risk of reinfection, with 34 percent having already had an infection and 29 percent having had sex with someone who had previously been infected. Fortunately, Gaydos adds, 89 percent of males tested said they would use the iwantthekit.org screening program again, citing how easy it was to simply mail in a penile swab. As part of the April campaign, whose slogan is “GYT”—text speak for “get yourself tested”—Gaydos plans to distribute iwantthekit.org fliers and brochures at shopping malls, recreation centers and libraries, all gathering spots for young people. She also plans to supply handouts to municipal public health departments and family-planning clinics throughout the region. To make kit ordering easier, the Johns Hopkins team has incorporated bar coding in its brochures and advertisements that can be read by standard computer apps, which are also free. People can take a picture of the bar code with their cell phone, open the app and be taken automatically to the ordering page of the iwantthekit.org website. Gaydos

says that this is very important for reaching underprivileged youth, especially many Hispanic and black teens and other young adults who cannot afford a home computer and whose access to the Internet is mainly through their smart phones. Home test kits can also be ordered through the website’s Facebook page. The Johns Hopkins team launched the iwantthekit.org program in Baltimore in part because of the city’s high infection rates. Baltimore consistently ranks among the top-10 U.S. cities for newly acquired cases of chlamydia. According to previous CDC biannual surveys of risky youth behaviors in the United States, 32 percent of students are sexually active by the ninth grade. In addition to Gaydos, Johns Hopkins researchers involved in these studies were Shua Chai, Mathilda Barnes, Bulbul Aumakhan, Mary Jett-Goheen, Nicole Quinn, Patricia Agreda and M. Terry Hogan. Additional research support was provided by Catherine Wright, of the Family Planning Clinics, Philadelphia; Wiley Jenkins, of the Department of Family and Community Medicine at the Southern Illinois University School of Medicine, Carbondale, Ill.; Cornelius Rietmeijer, of the Denver Public Health Department and the Colorado School of Public Health at the University of Colorado, Denver; and Pamela Whittle, of the Baltimore City Health Department. G

Related websites I Want the Kit:

www.iwantthekit.org

‘Sexually Transmitted Diseases’:

journals.lww.com/stdjournal/pages/ currenttoc.aspx

STD Awareness Month:

www.cdcnpin.org/stdawareness

Visit our website to view the beautiful landscaped grounds, amenities, and house-sized apartments. Call our friendly staff and ask out about our fantastic special leasing offers for Johns Hopkins Faculty and Staff! Hear what your colleagues are saying about us: “Located at the end of Roland Avenue in a picturesque location, nested between a school, playground and a golf course . . swimming pool, fitness club and ample jog space makes it ideal for people who love physical activity . . . an ideal home.” Venkat P. Gunareddy, MD JHU School of Medicine

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6 THE GAZETTE • February 14, 2011

CEO of Veolia Transportation to speak at Leaders + Legends Joseph joined the Connex North America executive team in 2001, when Yellow Carey Business School Transportation was acquired by Connex, then the transportation division of Vivendi ark Joseph, chief executive officer Environment, now Veolia Environment— and vice chairman of Veolia Transthe world’s largest environmental services portation, is the featured speaker at company. He became president and CEO the Johns Hopkins Carey Business School’s of Connex in 2004 and CEO and vice Leaders + Legends lecture series on Wedneschairman of Veolia Transportation in 2006. day, Feb. 16. The event will take place from Joseph also serves on the executive com7:30 to 9 a.m. at the Legg Mason mittee of Veolia Transport, the Tower in Harbor East. The title Paris-based parent company of of his remarks is “Transforming Veolia Transportation. Cities Through Smart Mobility: As CEO, Joseph has rapidly A Leading Transportation Comtransformed Veolia Transportapany’s Approach.” tion into the largest multimodal Committed to transforming transportation company on the and improving the quality of continent. He has directed urban life through well-designed, dynamic expansion of bus, rail, environmentally conscious paratransit, shuttle and taxi serand integrated transportation, vices, including privatization of Joseph began his career with Mark Joseph the New Orleans public transYellow Cab of Baltimore, where portation authority and the he served as president and CEO for 20 acquisition and expansion of SuperShuttle, years. Under his leadership, Yellow Cab which serves 30 airports throughout the grew from a small local operation into a nation. leading regional transportation company, An entrepreneur and innovator, Joseph Yellow Transportation, which was recogserves on numerous public, private and nized nationally for efficiency, customer nonprofit boards, and has lectured for the care and innovation in multiple modes of Wharton MBA program. He is a graduate of transportation. American University. During those years, Joseph served in The Leaders + Legends monthly breakfast numerous government advisory and indusseries, which features today’s most influential try leadership positions, including chairing business and public policy leaders addressing a governmental council on privatization topics of global interest and importance, is for the state of Maryland and serving as designed to engage business and community president of the TLPA, an international professionals in an examination of the most industry trade association. He started one compelling issues and challenges facing sociof the nation’s first paratransit services, creety today. ated the first urban auto-care mall and was a Admission to the lecture, which in founding member and chairman of the U.S. cludes breakfast, is $35. To register and Capital Chapter of the Young Presidents’ for more information, go to carey.jhu.edu/ Organization. leadersandlegends. By Andrew Blumberg

M First Lecture - Dr. Ben Bussey (APL) - Principal Investigator

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JHU_campus_halfpg_021011.indd 1

2/10/11 11:43 AM

February 14, 2011 • THE GAZETTE

Foreign Affairs Symposium to highlight global citizenship more majoring in international studies. Jilbert said of this year’s endeavor: “The goal of the symposium was to challenge the audience to consider their individual role in the global community. As the world becomes more and more interconnected, we are no longer confronted with local but global problems. These global problems are often said to require global solutions, yet the basis of these global solutions must be individuals who are willing to work together as responsible global citizens toward bettering their community,” he said. Coleman added, “We also hope to draw in a broader cross section of Greater Baltimore and Washington, D.C., audience members, in addition to Johns Hopkins students and staff. Several of our events appeal to students at the Carey Business School and the School of Advanced International Studies, and we are offering live webcasts of some events to those students. We also hope to coordinate our events with programs at the [university’s] Center for Social Concern, introducing local children to international issues and, in so doing, broadening their outlook.” The Foreign Affairs Symposium’s executive directors and staff begin to plan a year in advance, contacting possible speakers and fundraising throughout the Johns Hopkins and Baltimore communities. “Our staff works tirelessly with us all year to contact and schedule speakers, coordinate logistics and work every event,” Coleman said. “The energy and excitement of our staff is really the driving force of the symposium, and they deserve our collective thanks.” Berger said, “I have been fortunate to be on the staff of the Foreign Affairs Symposium for the past three years and been able to meet prominent figures in the field of international affairs. I’m looking forward to this year’s lineup, which I hope will motivate discussion around campus.” Each event is followed by a reception with the speaker (and a book signing, if applicable).

B y A m y L u n d ay

Homewood

he annual student-run Foreign Affairs Symposium at Johns Hopkins returns on Thursday, Feb. 16, when former Sen. Chuck Hagel will be the first of 10 prominent speakers to visit the Homewood campus during the spring semester. Hagel’s talk at 7 p.m. in 110 Hodson Hall begins the series of topical lectures and panel discussions under the 2011 theme, Global Citizenship: Re-examining the Role of the Individual in an Evolving World. Hagel is currently co-chairman of the president’s Intelligence Advisory Board, chairman of The Atlantic Council and a Distinguished Professor at Georgetown University. Doors open at 6:30 p.m. The next speaker in the lineup will be Cady Coleman, a NASA astronaut who will give her talk at 2:30 p.m. on Sunday, Feb. 20, while aboard the International Space Station. It will be broadcast from the Earth’s orbit to a screen in 213 Hodson Hall, which is a classroom set up with distance-learning capabilities. Other speakers making on-campus appearances this spring are Franklin Raines, former chairman and CEO of Fannie Mae (Thursday, Feb. 24, at 8 p.m. in Levering’s Glass Pavilion); Bob Woodward, author and journalist at The Washington Post (Tuesday, March 1, at 7 p.m. in Shriver Hall Auditorium); Richard Koo, chief economist of Nomura Research Institute (Wednesday, March 9, at 7 p.m. in the Glass Pavilion); Thomas Friedman, Pulitzer Prize–winning journalist for The New York Times (Thursday, March 10, at 8 p.m. in 110 Hodson); Ayaan Hirsi Ali, author of Infidel, scholar at the American Enterprise Institute and activist for women’s rights in Islamic societies (Tuesday, April 5, at 8 p.m. in Mudd Hall Auditorium); and R. Gil Kerlikowske, direc-

Ayaan Hirsi Ali

Thomas Friedman

Bob Woodward

Robert Mueller

Paul Selva

Cady Coleman

tor of the White House’s Office of National Drug Control Policy (Wednesday, April 13, at 8 p.m. at a location to be announced). Also expected to speak are Lt. Gen. Paul J. Selva, assistant to the chairman of the Joint Chiefs of Staff; and Robert Mueller, director of the Federal Bureau of Investigation. Dates, locations and other updates will be posted on the FAS website, www.jhu.edu/ fas. Other featured events of the symposium are a panel discussion on cybersecurity, featuring representatives from Northrop Grumman, Lockheed Martin and the Office of Innovative Technologies at the Mary-

land Department of Business and Economic Development (Monday, March 14, at 8 p.m. in the Glass Pavilion); and a discussion with two of the university’s Nobel laureates, Peter Agre, director of the Johns Hopkins Malaria Research Institute, and Carol Greider, director of Molecular Biology and Genetics in the Johns Hopkins Institute for Basic Biomedical Sciences (Friday, April 29, at 5 p.m. in Shriver Hall Auditorium). This year’s symposium was headed by Krieger School undergraduates Caroline Berger, a senior majoring in international studies; Isaac Jilbert, a junior majoring in sociology; and Kieran Coleman, a sopho-

Commons “Getting caramel off of baby toys, not fun,” Yassa said with a laugh. “I guess it comes with the territory now.” In his new role, Yassa has a simple directive: Be seen and be social. Yassa moved into Charles Commons in January with his daughter and wife, Manuella. The couple previously lived in Irvine, Calif., where Yassa finished his doctoral degree. Yassa, a goateed professor with an easy smile, replaced Amy Lynne Shelton, who had served as Charles Commons Faculty Fellow since the two-building complex opened in September 2006. Charles Commons, a 313,000-square-foot residential and retail facility located in Charles Village, was designed to be a hub of student life on the Homewood campus. It is the only campus building with a faculty in residence. Yassa coordinates the Charles Commons Connections program—which is open to all undergraduates, not just residents of the building—with the assistance of Craig Rosenblum, the current graduate assistant at Charles Commons, and Corey Michalos, an assistant director with the Office of Residential Life. Charles Commons Connections was launched in 2006 by Shelton and Paula Burger, then dean of undergraduate education, to foster community at Johns Hopkins. Throughout the year, the program runs activities that give students opportunities to interact socially with faculty and staff from the schools of Arts and Sciences and Engineering, and take a break from academics. Yassa said he hopes to build upon the legacy left by his predecessor and colleague. Shelton, an associate professor in the Department of Psychological and Brain Sci-

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Continued from page 1

Students at Charles Commons Connections—a program open to all undergraduates— sample a sugary confection. The participants also made their own Valentines.

ences, moved into the building with her husband, Matt Lindsey, and their 13-monthold son, Ryan. The two became regulars at the Charles Commons Connections events over the past four years. Lindsey, an amateur astronomer, instituted the Stargazing on the Charles Commons Roof event, which is now held once a semester. Shelton said that the program started off slowly but steadily built up steam. The main goals were to build community and just have fun. “We wanted faculty and students to talk outside the classroom in an informal setting. The activities all centered on putting people on an even playing field, the more interactive the better,” she said. “We didn’t want a psychology professor, for example, to talk about psychology but more of her day-to-day stuff. I had to twist some arms in the beginning, but once faculty came, they had a great time and we’ve had many repeat visits.” The program first instituted dinner nights,

when faculty would cook their favorite meals, often with the assistance of students. The dinners proved wildly popular and have become a staple. The program would later add pizza making, trivia nights, poker nights, seasonal events, day trips and more. In the past few years, students have gone on trips to see the Body Worlds exhibit at the Maryland Science Center, a show at the France-Merrick Performing Arts Center and even a Broadway play. The fall 2010 program featured 15 programs including “decorating a doorstop,” apple picking at Baugher’s Farm in Westminster, Md., a ghost tour and shopping in Fells Point, Halloween pumpkin carving and painting, cake decorating and gingerbread house making. In the 2009–2010 academic year, 94 faculty and staff volunteered for the program, which is supported by the Office of Student Life and the Parents Fund. Last Thursday, faculty and students par-

ticipated in a candy- and card-making event for Valentine’s Day in the Charles Commons community kitchen. Tomorrow night, the program will welcome President Ron Daniels for a “fireside chat” at 7 p.m. at the Charles Commons Salon C, located behind Nolan’s on 33rd. Yassa said he expects a big turnout. “We think President Daniels will tell the students what he does as president, and what inspired him to come to Johns Hopkins,” Yassa said. “But this is not him at a podium; it’s the president in a much more informal, personal setting. I’m sure the students will ask him about his vision for the university and undergraduate life. We’re really looking forward to it. The fireside chats were started in 2009 and have so far featured Susan Boswell, dean of student life; Paula Burger; and Michela Gallagher, vice provost for academic affairs. The speakers talk by a cardboard fireplace in an informal setting. Rosenblum said that the fireside chat and all the programs routinely get a strong turnout. He said 2010 was the program’s most successful year yet in terms of participation. “Now we have a track record. We learned what worked and what didn’t,” said Rosenblum, who is a graduate student in the Department of Materials Science and Engineering. “But we’re always looking for new ideas. We suggest ideas, but faculty and students can also pitch ideas of what they would like to do.” Yassa said he’s looking forward to the next two years at Charles Commons and making more connections between faculty and students. “Interacting is what this is all about,” he said. “We want people to be social and develop relationships through our programs.” G For a complete list of upcoming events, go to the Charles Commons Connections page on Facebook.

8 THE GAZETTE • February 14, 2011

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esearchers at the Johns Hopkins University School of Medicine have discovered that nitroxoline, an antibiotic commonly used around the world to treat urinary tract infections, can slow or stop the growth of human breast and bladder cancer cells by blocking the formation of new blood vessels. The results, appearing in the Dec. 15 issue of the Journal of the National Cancer Institute, suggest that nitroxoline shows promise as a potential therapeutic agent. “Angiogenesis, the growth of new blood vessels, plays an important role in tumor growth and metastasis, so inhibiting angiogenesis is a promising strategy for developing new anticancer drugs,” said Jun O. Liu,

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roposals for Arts Innovation Grants for the fall 2011 and spring 2012 semesters are now being accepted from Homewood faculty and students. The initiative is designed to help faculty develop for-credit interdisciplinary courses in the arts—across departments, divisions or institutions—for Homewood undergraduates, and to help undergraduates create new co-curricular activities in the arts or significantly increase the impact of existing ones within both the university and greater Baltimore communities. The deadline for submissions is Friday, March 4. For more information, go to www .library.jhu.edu/about/news/announcements/ artsinnovationgrants.html.

a professor of pharmacology and molecular sciences at Johns Hopkins. The research team tested more than 177,000 chemical compounds and drugs for their ability to block the activity of a protein called MetAP2, which is implicated in the formation of new blood vessels. Previous research had shown that inhibiting MetAP2 leads to a cascade of molecular events that ultimately prevents vessel-forming cells from growing. The team first tested 175,000 chemicals for their ability to block MetAP2 activity. Of the 294 chemicals found to reduce MetAP2 activity by at least half, nitroxoline stood out in its ability to inhibit MetAP2 by more than 99 percent at low and safe concentration. “It was one of the most potent hits we identified from this chemical compound library,” Liu said. At the same time, the team tested 2,687 FDA-approved or commonly used drugs in the Johns Hopkins Drug Library for their ability to stop blood vessel–forming cells from growing. The research team grew human umbilical vein endothelial cells, or HUVEC, in tiny wells and treated each well with a different drug from the library. Of the 210 drugs that inhibited HUVEC growth by at least half, nitroxoline again stood out; it inhibited cell growth by 95.5 percent at the same concentration that blocked MetAP2. The team then tested nitroxoline for its ability to stop blood vessel growth in mice. They treated 10 mice with growth factors that encourage new vessel growth, then treated half with nitroxoline and, for comparison, the other half with only salt solution. After 10 days they discovered that untreated mice developed on average 48.6 new vessels per microscope field—the area visible when looking at the tissue through a microscope—whereas nitroxoline-treated mice developed on average only 20 new vessels per microscope field. “Because nitroxoline showed such a substantial inhibitory effect, we moved on to see if it would have an effect on tumors in

mice,” Liu said. Mice carrying transplanted human breast or bladder cancer cells were treated with nitroxoline injections every other day for a month in the case of breast cancer, or every day for two weeks in the case of bladder cancer. Nitroxoline treatment reduced breast cancer cell tumor volume by 60 percent and bladder cancer cell tumor by more than 50 percent. “There are limitations of this study, but we find the results encouraging enough to pursue further study of nitroxoline for preclinical and clinical use in treating bladder carcinomas,” Liu said. This study was funded by the Patrick C. Walsh Prostate Cancer Research Fund, National Cancer Institute, Flight Attendant Medical Research Institute, Keck Foundation, Prostate Cancer Foundation and National Institutes of Health’s Medical Scientist Training Program, National Center for Research Resources and Roadmap for Medical Research. In addition to Liu, authors on the paper are Joong Sup Shim, Shridhar Bhat, Benjamin Nacev, Jing Xu, Hyo-eun Bhang, Surajit Dhara, Kee Chung Han, Curtis Chong and Martin Pomper, all of Johns Hopkins; and Yoshiyuki Matsui and Alan So, both of Vancouver General Hospital and University of British Columbia, Canada.

Related websites ‘Journal of the National Cancer Institute’:

jnci.oxfordjournals.org

Jun O. Liu:

www.hopkinsmedicine.org/ pharmacology/research/liu.html

www.hopkinsmedicine.org/ institute_basic_biomedical_ sciences/about_us/scientists/ jun_liu.html

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February 14, 2011 • THE GAZETTE F E B .

1 4

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2 1

Calendar Continued from page 12 Mon.,

Feb.

14,

12:15

p.m.

“Ethics at the Frontiers of Science: Approaches to the Oversight of Controversial Technologies,” a Berman Institute of Bioethics seminar with Jeffrey Kahn, University of Minnesota. W3008 SPH. EB Mon., Feb. 14, 1:30 p.m. “Does Our Current Understanding of Motor Learning Help Neurological Patients?” a Biomedical Engineering seminar with Amy Bastian, Kennedy Krieger Institute and SoM. 110 Clark. HW (Videoconferenced to 709 Traylor. EB )

“Fragments of an Indian Ocean Life: Aristide Corroller Between Islands and Empires,” a History seminar with Pier Larson, KSAS. Co-sponsored by Humanities. 308 Gilman. HW

Mon., Feb. 14, 4 p.m.

Tues., Feb. 15, 10 a.m. “Innova-

tive Programs for Sexually Transmitted Disease Control at the Baltimore City Health Department,” a Population, Family and Reproductive Health thesis defense seminar with Elizabeth Temkin. W3031 SPH. EB “GPCR Signaling in Primary Cilia: Linking Bardet-Biedl Syndrome, Hedgehog and Tubby,” a Biological Chemistry seminar with Peter Jackson, Genentech Inc. 612 Physiology. EB

Tues., Feb. 15, noon.

Tues.,

Feb.

15,

12:10

p.m.

“Intimate Partner Violence, HIV/AIDS and Substance Use Syndemic Among Low-Income Urban Women,” a Graduate Seminar in Injury Research and

Policy seminar with Samantha Illangasekare, SPH. Sponsored by the Center for Injury Research and Policy, the Center for the Prevention of Youth Violence and the Center for Gun Policy and Research. 208 Hampton House. EB Tues., Feb. 15, 1:30 p.m. “Unified Approach for Minimizing Composite Norms,” an Applied Mathematics and Statistics seminar with N. Serhat Aybat, Columbia University. 304 Whitehead. HW

The M. Gordon Wolman Seminar— “Flooding and Flow Path Selection on Alluvial Fans and Deltas” with Douglas Jerolmack, University of Pennsylvania. Sponsored by Geography and Environmental Engineering. 234 Ames. HW

Tues., Feb. 15, 3 p.m.

Tues., Feb. 15, 4:30 p.m. “A Brief History of the Penn Treebank,” a Center for Language and Speech Processing seminar with Mitch Marcus, University of Pennsylvania. B17 Hackerman. HW Wed.,

Feb.

16,

12:15

p.m.

Wednesday Noon Seminar—“You Can’t Spell GENETIC EPIdemiology Without Epigenetics” with Dani Fallin, SPH. Sponsored by Mental Health. B14B Hampton House. EB “The Association of Obesity With Thyroid Cancer Risk and Markers of Thyroid Function,” an Epidemiology thesis defense seminar with Cari Meinhold Kitahara. W3030 SPH. EB

Wed., Feb. 16, 1 p.m.

Wed. Feb. 16, 3 p.m. “Molecular

Dynamics Simulations of Reactive

Capillary Flow,” a Materials Science and Engineering seminar with Edmund Webb III, Lehigh University. 110 Maryland. HW “Damage Control—Role of PINK1 and Parkin in Mitochondrial Autophagy and Parkinson’s Disease,” a Pharmacology and Molecular Sciences seminar with Richard Youle, NINDS/NIH. West Lecture Hall (ground floor), WBSB. EB

Wed., Feb. 16, 4 p.m.

“Covarience Matrix Estimation via Convex Optimization: Theory, Methods, Algorithms and Applications,” a Biostatistics seminar with Xi Luo, The Wharton School of the University of Pennsylvania. W2030 SPH. EB

Wed., Feb. 16, 4 p.m.

“Carbon Footprints: The Politics of Producing Energy Emissions,” a SAIS Canadian Studies Program thesis defense seminar with Robert Shum. 806 Rome Bldg. SAIS

Thurs., Feb. 17, 9 a.m.

Thurs.,

Feb.

17,

a.m.

“Metabolomics to Understand Disease Pathogenesis and Drive Therapeutic Discovery,” a Biological Chemistry seminar with Gary Patti, Scripps Research Institute. Mountcastle Auditorium, PCTB. EB

“The Effect of Adolescent Cigarette Smoking on Mental Health and Substance Use Outcomes in Adulthood,” a Health, Behavior and Society thesis defense seminar with Carol Strong. 744 Hampton House. EB

Thurs., Feb. 17, 10 a.m.

Thurs., Feb. 17, 10:45 a.m.

“Complexity of the Graph Reachability Problem,” a Computer Sci-

ence seminar with Vinod Variyam, University of Nebraska-Lincoln. B17 Hackerman. HW Feb. 17, noon. The Bromery Seminar—“The Origin and Evolution of Compositionally Stratified Continental Arc Crust” with Rebecca Lange, University of Michigan. Sponsored by Earth and Planetary Sciences. Olin Auditorium. HW

Thurs.,

Thurs., Feb. 17, noon. “GeneBased Vaccines Against Exotic Viral Diseases,” a Molecular Microbiology and Immunology/ Infectious Diseases seminar with Jay Hooper, U.S. Army Medical Research Institute of Infectious Diseases. W1020 SPH. EB

“Transcriptional Control of Neuronal Diversity,” a Neuroscience research seminar with Jane Johnson, University of Texas Southwestern Medical Center. West Lecture Hall (ground floor), WBSB. EB

Thurs., Feb. 17, 1 p.m.

Thurs.,

Feb.

17,

1:30

p.m.

“The Use of Active-Set Phases to Accelerate Optimization Algorithms,” an Applied Mathematics and Statistics seminar with Daniel Robinson, Northwestern University. 304 Whitehead. HW Thurs., Feb. 17, 4 p.m. “Mechanisms Coordinating Protein Synthesis and Folding Throughout Evolution,” a Biology seminar with Jose Barral, University of Texas Medical Branch. 100 Mudd. HW

“Structural and Kinetic Insights Into the Mechanism of AMPylation by VopS Fic Domain,” a Carnegie Institution Embryology seminar with Phi Luong, University of Texas Southwestern Medical Center. Rose Auditorium, 3520 San Martin Drive. HW

Fri., Feb. 18, 2 p.m. “Developing GAL4/UAS Transgenic Tools to Probe Zebrafish Neural Function,” a Carnegie Institution Embryology thesis defense seminar with Courtney Akitake. Rose Auditorium, 3520 San Martin Drive. HW Mon., Feb. 21, noon. “Transcriptional Pausing: A Unique Mechanism in the Regulation of Hematopoietic Differentiation,” a Biological Chemistry seminar with Xiaoying Bai, Children’s Hospital Boston. 612 Physiology. EB Mon., Feb. 21, noon. “Genetic and Imaging Analysis of Glial Cell Development in Zebrafish,” a Biochemistry and Molecular Biology seminar with Bruce Appel, University of Colorado School of Medicine. W1020 SPH. EB Mon.,

Feb.

21,

12:15

p.m.

“Using Mouse Genetics to Unravel the Pathways That Regulate Morphogenesis,” a Carnegie Institution Embryology seminar with Irene Zohn, Children’s Research Institute. Rose Auditorium, 3520 San Martin Drive. HW SYMPOSIA

The 2011 Foreign Affairs Symposium—Global Citizenship: Re-examining the Role of the Individual in an Evolving World with former Sen. Chuck Hagel. (See story, p. 7.) 110 Hodson. HW

Thurs., Feb. 17, 7 p.m.

Fri., Feb. 18, 12:15 p.m.

Thurs., Feb. 18, 12:15 p.m.

“Aging and the Conservation of Energy,” an Epidemiology thesis defense seminar with Jennifer Schrack. W4030 SPH. EB

W OR K S HO P S Thurs., Feb. 17, 1 p.m. “Using YouTube for Research and Instruction,” a Bits & Bytes workshop, providing an introduction and an overview of the popular videosharing network. The training is open to Homewood faculty, lecturers and TAs; staff are also welcome to attend. Sponsored by the Center for Educational Resources. Garrett Room, MSE Library. HW

Internal med residents graduate unprepared for primary care Study shows residency redesign needed to ready doctors for outpatient care By Stephanie Desmon

Johns Hopkins Medicine

octors who have completed training in internal medicine are in general poorly prepared for jobs as primary care physicians, most notably lacking the knowledge to best care for patients with chronic conditions such as diabetes, hypertension and high cholesterol, a new Johns Hopkins study suggests. The researchers also found, however, that physicians who completed internal medicine residency programs at community hospitals were significantly better prepared to treat patients in an outpatient setting than physicians who trained at academic medical centers. One likely reason for the gaps in knowledge is the focus in medical training on inpatient care at the expense of outpatient care, the bread and butter of any physician, the researchers say. Ninety percent of all doctor-patient visits are outpatient, even in specialty care.

“When I graduated from residency here, I knew much more about how to ventilate a patient on a machine than how to control somebody’s blood sugar, and that’s a problem,” said general internist Stephen Sisson, an associate professor of medicine at the Johns Hopkins University School of Medicine and leader of the study published in the January issue of The American Journal of Medicine. “The average resident

Related website Stephen Sisson:

www.hopkinsmedicine.org/gim/ faculty/sisson.html

doesn’t know what the goal for normal fasting blood sugar should be. If you don’t know what it has to be, how are you going to guide your diabetes management with patients?” The need for primary care doctors is growing. And as the population ages, there is a greater need for physicians to manage chronic diseases for the long term. Studies have shown that populations with better access to good internists spend less time in the hospital and cost less to treat. Experts have long been concerned that residents

are leaving training unprepared to face the sort of patients who will walk into their examination rooms, Sisson says. One-third of internal medicine residency is supposed to be devoted to outpatient care, but not all of that time is spent on primary care. Some is spent on outpatient specialty care, and some is even spent rotating through the emergency department, he adds. “We need to change the way we teach residents,” he said. “If the mission of internal medicine residency programs is to meet society’s health care needs, then our results suggest that these training programs are failing.” Sisson’s study looked at the performance of internal medicine residents on a curriculum created by the Johns Hopkins Internet Learning Center and used during the 2006– 2007 academic year by 67 medical residency programs in the United States. The Johns Hopkins curriculum is now used by twice that many programs, serving 10,000 residents. There are 38 online training modules, in topics from cancer screening to headaches to depression, designed to supplement the lectures and clinical care of residency. Each module is written on the level of a practicing internist and the pretest, lesson and post-test take approximately 45 minutes to complete. Sisson looked at the performance of resi-

dents at the end of the first, second and third years. At the beginning, residents from academic medical centers and community hospitals performed equally poorly. But by the end of the third year, there was a much wider knowledge gap, with community hospital residents doing better, particularly in acute care areas such as the treatment of pneumonia, dizziness and gastroesophageal reflux disease. Still, residents at both kinds of hospitals failed to score more than 55 percent overall on topics such as chronic disease management, preventive care and acute care— exactly the type of cases a primary care doctor would encounter in private practice. Chronic disease management was the worst across the board, with neither resident type scoring above 50 percent. The data suggest a drop-off in learning between the end of the second and third years of residency. Sisson says that some of that could be attributed to residents who have decided to pursue fellowships in specialty areas and may not try as hard to learn concepts that won’t apply to those specialties. He says that more community hospital residents tend to go into primary care, which could explain why they do better on tests of internal medicine knowledge. Deepan Dalal also worked on the study.

10 THE GAZETTE • February 14, 2011 P O S T I N G S

B U L L E T I N

Job Opportunities The Johns Hopkins University does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or other legally protected characteristic in any student program or activity administered by the university or with regard to admission or employment.

Homewood

Office of Human Resources: Suite W600, Wyman Bldg., 410-516-8048 JOB#

POSITION

45459 45953 45976 46001 46002 46011 46013 46014 46048 46050 46055 46064 46065 46071

Sourcing Specialist Employer Outreach Specialist Associate Dean Librarian III DE Instructor, CTY Research Specialist Sr. Financial Analyst Budget Analyst Admissions Aide Research Program Assistant II Research Technologist DE Instructor, CTY Assistant Program Manager, CTY Volunteer and Community Services Specialist

46078 46085 46088 46090 46093 46097 46106 46108 46111 46127 46133 46152 46164 46166 46171 46179 46213 46215 46216 46267 46274

Student Career Counselor Laboratory Coordinator Annual Giving Officer Campus Police Officer Curriculum Specialist LAN Administrator III Outreach Coordinator Executive Assistant Center Administrator Monitoring and Evaluation Adviser Employee Assistance Clinician HR Manager Sr. Software Engineer Proposal Officer Sr. Staff Engineer Research Program Assistant Custodian Mail Clerk Software Engineer Training Facilitator Academic Program Coordinator

Notices CER Fellowship Grants — Applications

are invited for the 2011–2012 Technology Fellowship Program, a mini-grant initiative administered by the Center for Educational Resources of the Sheridan Libraries. The program is intended to encourage faculty to develop creative uses of digital technologies to enhance teaching and learning by partnering with student fellows. Teams must include at least one faculty member who teaches full-time undergraduates and one or more full-time graduate or undergraduate students. Details are available in the “Program Guidelines” document through the CER website, www.cer.jhu.edu. Applications are

Office of Human Resources: 2021 East Monument St., 410-955-3006 JOB#

43084 43833 44899 44976 44290 44672 41388 44067 44737 44939 44555 44848 44648 44488 43425 43361 44554

POSITION

Academic Program Coordinator Grant Writer Maintenance Worker Food Service Worker LAN Administrator III Administrative Secretary Program Officer Research Program Assistant II Sr. Administrative Coordinator Student Affairs Officer Instructional Technologist Sr. Financial Analyst Assay Technician Research Technologist Research Nurse Research Scientist Administrative Specialist

School of Medicine

Office of Human Resources: 98 N. Broadway, 3rd floor, 410-955-2990 JOB#

38035 35677 30501 22150 38064

44684 42973 43847 45106 45024 42939 43754 42669 44802 44242 44661 45002 44008 44005 41877 44583 44715 44065 44112 44989 44740 39063 44603

Biostatistician Clinical Outcomes Coordinator Sr. Programmer Analyst Employment Assistant/Receptionist Payroll and HR Services Coordinator Research Data Coordinator Malaria Adviser Data Assistant Budget Specialist Academic Program Administrator Sr. Research Program Coordinator Research Observer Manuscript Editor, American Journal of Epidemiology Research Service Analyst Health Educator Multimedia Production Supervisor Research Program Coordinator Research Data Manager Sr. Laboratory Coordinator Sr. Research Assistant Sr. Administrative Coordinator Research Assistant Budget Analyst

37442 37260 38008 36886 37890

Sr. Administrative Coordinator Sr. Administrative Coordinator Sponsored Project Specialist Program Administrator Sr. Research Program Coordinator

POSITION

Assistant Administrator Sr. Financial Analyst Nurse Midwife Physician Assistant Administrative Specialist

This is a partial listing of jobs currently available. A complete list with descriptions can be found on the Web at jobs.jhu.edu.

Woodcliffe Manor Apartments

S PA C I O U S

G A R D E N A PA RT M E N T L I V I N G I N

R O L A N D PA R K

• Large airy rooms • Hardwood Floors • Private balcony or terrace • Beautiful garden setting • Private parking available • University Parkway at West 39th St. 2 & 3 bedroom apartments located in a private park setting. Adjacent to Johns Hopkins University Homewood Campus and minutes from downtown Baltimore.

410-243-1216

105 West 39th St. • Baltimore, MD 21210 Managed by The Broadview at Roland Park BroadviewApartments.com

accepted through March 31; awards will be announced in mid-April. Funding for these awards is available from May 2011 to April 2012. Clothing Drive — The Office of Work, Life and Engagement is collecting new and gently used professional men’s and women’s clothing for individuals just entering or reentering the workforce. Donations will be collected through Feb. 21 in support of the employment programs and services of Suited to Succeed, Housing the Homeless Initiative and Paul’s Place. To locate a university donation dropoff site, go to www.hopkinsworklife.org/ community/clothing_drive.html. For general questions, contact Brandi Monroe-Payton at bmonroe6@jhu.edu or 443-997-6060.

Accountable care at academic medical centers: Lessons learned By Gary Stephenson

Johns Hopkins Medicine Schools of Public H e a l t h a n d N u r s i n g

B O A R D

cademic medical centers must adjust and adapt to the new health care reform laws or risk marginalization in the new health care arena, according to a New England Journal of Medicine “Perspective” article published online Feb. 2. The authors of the article, Scott A. Berkowitz, a fellow in cardiology and geriatrics at the Johns Hopkins University School of Medicine, and Edward D. Miller, dean of the Johns Hopkins School of Medicine and CEO of Johns Hopkins Medicine, argue that academic medical centers, or AMCs, can not only remain relevant in the face of sweeping change but can lead the way by serving as examples of successful transformation while continuing to excel in achieving their mission. For some AMCs, this may take the form of becoming accountable care organizations, or ACOs, as established in the Affordable Care Act. First and foremost, the authors say, AMCs must have an integrated system of sufficient size and breadth to provide necessary and timely inpatient and outpatient services across the full continuum of care, including primary and specialty care. Second, AMCs need to assess the financial risk associated with pursuing ACO status. The authors note that the Affordable Care Act allows for various ACO payment models based on the level of risk that the health care organization assumes. For example, under

partially capitated models, the ACO would be at risk for the cost of some, but not all, of the services covered by Medicare. Third, AMCs need a robust health information technology platform that captures all patient-encounter information into a standardized system that permits providers to share information, enhances clinical decision making and facilitates rapid analysis of input data. Last, and potentially most challenging, is changing the historic culture of AMCs, which traditionally favor—in terms of advancement—faculty grant support, publications and scholarly reputation over contributions to high-quality care. The authors cite several examples from the Johns Hopkins Medicine experience that illustrate successful components of an accountable care organization–like model, including health system network expansion, increases in primary care capability and success in managing capitated care programs. “Despite the barriers to becoming an accountable care organization,” Berkowitz said, “health care reform brings great opportunities for academic medical centers to modernize their approaches to research, education and clinical care.” Added Miller, “In many important respects, academic medical centers are ideally positioned to implement meaningful health care reform. They have the requisite infrastructure, intellectual capital and networks to spearhead efforts to develop, pilot and disseminate new patient-focused measures and care models,” he said.

Study to evaluate if ‘dummy’ education is smart for nurses

ow can patient simulators—hightech manikins that respond to a nurse’s care—help prepare the nurses of tomorrow? The Johns Hopkins University School of Nursing is among 10 nursing schools nationwide collaborating on a landmark study to find out just how smart this “dummy” education can be. “Nursing students have been learning their clinical skills the same way for more than 40 years, but the health care environment has changed,” said Pamela Jeffries, associate dean for academic affairs. “The patients have changed, their acuity has changed, the knowledge required of our nurses has changed, so the way we educate nurses has to change, too.” Schools have been experimenting with patient simulations for several years, but their effectiveness has been evaluated with only a handful of small studies. This simulation study, conducted by the National

Council of State Boards of Nursing, seeks to change that. Researchers at 10 nursing schools will follow more than 1,000 students throughout their education and into the first year of their careers to discover how using simulations in learning affects performance in the workplace after graduation. Incoming students at the study schools, including Johns Hopkins, may choose to begin participating in the study starting this fall. “Using simulations allows nursing students to step into the role of a full-fledged nurse for a time,” Jeffries said. “When they are with the manikin, they have to make decisions without advice from a teacher or experienced nurse. They can make mistakes and learn from them without the fear of harming a patient. I think simulations will be a key component in educating our future nurses, and this study will give us the data we need to provide the best education possible.”

February 14, 2011 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT

Belvedere, beautifully renov’d 3BR, 2BA TH, available June. $1,600/mo (furn’d) or $1,450/mo (unfurn’d). 410-929-6008 or belvedererental@gmail.com. Bolton Hill, 2 big BRs and 2.5BAs in immaculate TH, hdwd flrs, recent apps, AC, new roof/windows, porch, bsmt, 2 prkng spaces, 4-min walk to metro, avail July. $1,850/mo. 410-383-7055 or viLca11@ gmail.com. Bolton Hill, beautiful 1BR, 1BA apt on Park Ave, 1,300 sq ft, 8 rms, separate guest rm, office and dining rm. $1,595/mo. gbaranoski@ covad.net. Charles Village, beautiful 1BR, 1BA apt, close to shuttle and Homewood campus, available April. 410-404-2330. Charles Village, spacious, bright 3BR apt, 3rd flr, newly updated, nr Homewood campus. $1,350/mo. 443-253-2113 or pulimood@aol.com. Deep Creek Lake/Wisp, cozy 2BR cabin w/ full kitchen, call for wkly/wknd rentals, pics avail at jzpics@yahoo.com. 410-638-9417. Fells Point, great, fully rehabbed 2BR apt, walking distance to Hopkins. $1,400/mo. 410-205-5503. Hampden, 3BR, 2BA TH, dw, W/D, fenced yd, nr light rail. $1,100/mo + utils. 410378-2393. Harborview (23 Pier Side Drive), 1BR unit, great views of water and swimming pool, 2 health clubs, garage prkng, 24-hr security incl’d, safe area; applicant must have good credit. $1,600/mo. 443-471-2000. Mayfield, charming 3BR, 2BA house in historic neighborhood, hdwd flrs, fp, garage, yd and patio, nr Homewood/JHH/Bayview. $1,800/mo. 410-852-1865 or miriam .mintzer@gmail.com. Ocean City, Md, 3BR, 2BA condo (137th St), ocean block, steps from beach, offstreet prkng (2 spaces), lg pool, walk to restaurants/entertainment. 410-544-2814. Parkville, charming 1BR, 1BA cottage house w/huge yd, hdwd flrs, W/D, bsmt, driveway. $900/mo. 410-422-0146 or pelelika2001@ yahoo.com. Pikesville, sublet a lovely, lg 1BR, 1BA apt, available from March 1 to May 31. $750/ mo. 443-934-3750. Reisterstown, 3BR, 2.5BA TH, lg, spacious rms, new appls, deck, backyd, 10 mins to Owings Mills metro. $1,500/mo. www.21136rent.com (for pics and details). Roland Park, spacious 2BR, 2BA condo, furn’d, W/D, walk-in closet, swimming pool, cardio equipment, .5 mi to Homewood, secure area. $1,600/mo. 410-218-3547 or khassani@gmail.com. Rosedale, 1BR divided rancher, lg living rm and dining rm, complete kitchen, new refrigerator/windows/crpt, washer, garage, lg backyd, quiet. $925/mo. 410-598-2819 or carlostaylorart@verizon.net. Towson/Loch Raven area, 3BR, 2BA TH, located on bus line to JHU Homewood, move in middle to end of February. $1,600/ mo. hous-vxz9a-2190776642@craigslist.org. WYMAN COURT HICKORY HEIGHTS Beech Ave. adj. to JHU!

Studio from $570 1 BD Apt. from $675 2 BD from $785

Hickory Ave. in Hampden, lovely Hilltop setting!

2 BD units from $750, or, with Balcony - $785!

Shown by appointment - 410-764-7776

www.BrooksManagementCompany.com

M A R K E T P L A C E

Wyman Park, sunny 2BR apt, AC, laundry in bldg, easy walk to Homewood/JHMI shuttle, avail May 15. $1,150/mo. 443-615-5190. Sublet 2BR apt nr Homewood campus and JHMI shuttle stop, W/D, closed prkng at extra charge, on-site swimming pool, current lease ends Aug 30; option to renew. 410-336-3620. Beautiful 3BR, 2BA condo w/garage, spacious, great location, walk to Homewood campus. $1,800/mo. 443-848-6392 or sue .rzep2@verizon.net. 2BR + study penthouse condo, opposite the Homewood tennis courts, avail April 1, no pets. $1,650/mo. healthxdesign@gmail.com. Storage garage avail, .7 mi to JHH, 24-hr access w/security gates. $100/mo. 410-2942793.

HOUSES FOR SALE

Belair-Edison, 3BR, 1.5BA RH in familyoriented, quiet neighborhood, CAC/heat, hdwd flrs, fin’d bsm, carport and ample street prkng, 15 mins to JHH/JHU, 5 mins to Bayview. $100,000. 443-413-3644. Gardens of Guilford, newly renov’d, lg 2BR, 2BA condo in elegant setting, easy walk to Homewood campus. 410-366-1066. Gardenville, 3BR, 1.5BA RH in quiet neighborhood, new kitchen and BA, CAC, hdwd flrs, club bsmt w/cedar closet, fenced, maintenance-free yd w/carport, 15 mins to JHH. $139,500. 443-610-0236 or tziporachai@ juno.com. Mt Washington, affordable 3BR, 2.5BA house, Deep Cape, fin’d bsmt, sunrm, yd, nr park and best elementary school. 410491-3133. Mt Washington (5905 Pimlico Rd, enter through gate of Falls Village), 1865 farmhouse on private rd, acre of open and wooded land, 3BRs, orig wide fir plank flrs, lg updated kitchen, stunning 1,600 sq ft deck; call for appointment. 443-562-1634. Roland Park, beautiful 4BR, 2BA family home, off-street prkng, easy walk to Homewood campus. Dorsey, 410-967-3661. Lg 1BR condo in luxury high-rise, secure bldg w/doorman, W/D, CAC/heat, swimming pool, exercise rm, nr Guilford/JHU. $179,000. 757-773-7830 or norva04@gmail .com.

and sm cat. 951-603-9743 or sarah.kalia@ gmail.com.

Depression/bipolar support group, Sundays 11 am-12:30pm at Grace Fellowship Church, Lutherville. Dede, 410-486-4471 or dedebennett@comcast.net.

CARS FOR SALE

Responsible, loving pet-, baby- or housesitter, avail, JHU employee has experience w/special needs children and cats/dogs, refs available. 202-288-1311 or janyelle.marie@ hotmail.com.

’99 Mercury Cougar, automatic, power everything, premium wheels, leather interior, sunroof, rear spoiler, rear windshield wiper, AC, 20-26 MPG, 153K mi. $2,950. 443-604-5807. ’06 Kia Sedona minivan, automatic, power windows/locks, entertainment system, pads and rotors replaced, tires 1 yr old, 1 owner (nonsmoker), well-maintained, 87K mi. $8,500. 410-459-9803 or maherclan@ comcast.net.

ITEMS FOR SALE

Ski equipment for a 7- to 12-yr-old child: boots, helmet, poles. 410-580-9479 (eve). Heavy-duty motorized electric scooter, weight capacity up to 500 lbs, brand new, serious calls only. $2,000/best offer. 410562-5740. Moving sale: new queen-size bed, sofa, dining table, computer table and chairs, new mountain bike; Lenovo Thinkpad laptop, 4GB RAM, 360GB HDD, new, $350. 410585-4073 or phrvimta@yahoo.com. Dining rm set, table w/leaf, 4 chairs, china cabinet and sideboard, in excel cond. $225. 410-633-2064. Single mattresses (3) and boxsprings w/rails, in very good cond. $55/ea. 410-558-1797 (after 8pm). Lululemon hoodies (2), blue remix hoodie, size 8, and black and white reversible scuba hoodie, size 8; in excel cond. 410-2156575. GE built-in dishwasher, white, model# GSD2300RWW, $90; GE countertop microwave, $15; Simplehuman trash can, lg, semi-round, dk red, $15; porcelain farmhouse sink, white, $25; brass chandelier, $15. 410-889-0250 or aweil@baitman.org. German Shepherd puppies (born 11/19/10), up-to-date on shots, crate-trained, very friendly, parents on premises. $800/ea. 410245-0504 or braloubi@gmail.com. Conn alto saxophone, best offer; exercise rowing machine, $50; both in excel cond. 410-488-1886. Printer, dresser w/shelves, three-step ladders (2), sand beach chairs (2), reciprocating saw, digital piano. 410-455-5858 or iricse .its@verizon.net.

Furn’d BR and own BA in 3BR, 2BA apt in Fells Point, W/D, free Internet access, quiet street, best neighborhood, close to everything, 15-min walk to SoM. $350/mo to $400/mo + utils. xzhan45@gmail.com. Go apt hunting w/respectful 35-yr-old researcher, location/date flexible, no drugs/ no smoking, up to $850/mo incl utils. ys4cL@yahoo.com. Young F prof’l wanted to share new 2BR, 2.5BA house in Patterson Park, master BR w/armoire, easy prkng in front or nr house, 2 blks to park, great neighbors; utils and Internet incl’d in rent. 908-347-7404 or slvdels@ yahoo.com. F roommate wanted nr Homewood campus, 5-min walk to JHU shuttle stop. 734-2773168 or shammku@yahoo.com. 1BR avail in 2BR Mt Vernon apt, safe, 5 mins to Hopkins shuttle, share w/friendly F

Visiting professor looking for apt/house to sublet, approx May 25-June 25, pref familyfriendly neighborhood safe for walking w/ access to JHU shuttle (Roland Park, Homewood, etc.). info@tobiasfreund.de. Database programmer/volunteer needed for ambitious ecology project. Mark, 410-4649274. LCSW-C providing psychotherapy for adults and couples w/sexual health or sexuality concerns, EHP accepted. 410-235-9200 #6, or shane.grant.lcswc@gmail.com. Absolutely flawless detailing and mobile power-wash service. Jason, 443-421-3659. Piano/harpsichord lessons offered by Peabody Institute grad student, reasonable rates; call to schedule an appointment. 425-890-1327. Need a photographer or videographer for weddings or other events? Edward S Davis photography/videography. 443-695-9988 or esdavisimaging@gmail.com. Friday Night Swing Dance Club, open to public, great bands, no partners necessary. 410-663-0010 or www.fridaynightswing.com. Licensed landscaper avail for lawn maintenance, yd cleanup, fall/winter leaf and snow removal, trash hauling. Taylor Landscaping LLC. 410-812-6090 or romilacapers@ comcast.net. Affordable and professional landscaper/certified horticulturist available to maintain existing gardens, also designing, planting or masonry; free consultations. David, 410683-7373 or grogan.family@hotmail.com. Need help with your JHU retirement plan investments portfolio? Free, confidential consultation. 410-435-5939 or treilly1@ aol.com. Tutor for all subjects/levels; remedial and gifted; also help w/college counseling, speech and essay writing, editing, proofreading, database design and programming. 410-337-9877 (after 8pm) or i1__@ hotmail.com.

Ikea furniture, twin bed w/mattress, $75; lg bookcase, $30; in great cond. 443-4156949.

Clarinet and piano lessons available from current Peabody clarinet master’s student, competitive rates. 240-994-6489 or hughsonjennifer@gmail.com.

SERVICES/ITEMS OFFERED OR WANTED

Piano lessons w/Peabody alum w/doctorate, patient instruction, all levels/ages welcome. 410-662-7951.

Responsible F college student looking to babysit family for the summer, has car, Red Cross CPR- and babysitting-certified. ctgodack@eckerd.edu.

Learn Arabic w/experienced native teacher, MSA and colloquial, all levels, lessons tailored to your needs, individual or group. thaerra@hotmail.com.

Flea market, Saturday, Feb 19, 9am-1pm, 37th and Roland Ave (in Hampden nr Homewood campus). 410-366-4488 (to reserve tables).

Pampered chef offers kitchen and entertainment items, browse catalog or contact me to purchase, host a party or with questions. www.pamperedchef.biz/donnawirt.

ROOMMATES WANTED

Furn’d rm in new TH, walking distance to JHMI, pref nonsmoker/no pets. $550/mo + 1/3 utils. 301-717-4217 or jiez@jayzhang .com.

Free: LazyBoy recliner, blue, in good cond, comfy; you haul. wreisig4@comcast.net.

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines: • One ad per person per week. A new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 410-343-3362.

12 THE GAZETTE • February 14, 2011 F E B .

1 4

–

2 1

Calendar

Program discussion with Ato Kwamena Onoma, Yale University. For information, e-mail itolber1@ jhu.edu or call 202-663-5676. 736 Bernstein-Offit Bldg. SAIS “Can the Euro Survive? Lessons From Latin America,” a SAIS Latin American Studies Program discussion with Desmond Lachman, American Enterprise Institute. To RSVP, e-mail jzurek1@jhu.edu or call 202-663-5734. 517 Nitze Bldg.

Wed., Feb. 16, 12:45 p.m.

B L OO D D R I V E S Tues., Feb. 15, 7:30 a.m. to 5:45 p.m., and Wed., Feb. 16, 10:30 a.m. to 5:30 p.m. JHU/

SAIS

American Red Cross blood drive. For more information, go to www .membersforlife.org/ rccm/mobilesch/login .php?sponsorcode=1008, or call 443-997-6060. Glass Pavilion, Levering. HW

F I L M / V I D EO Thurs., Feb. 17, 5 p.m. Screening of the film Hiding Divya, an exploration of the stigma against mental illness, followed by a panel discussion and Q&A with the film’s director, Rehana Mirza. Sponsored by the SPH Behavioral Health International Group. W1214 SPH. EB

Mon., Feb. 21 (through Feb. 2 3 ) , 7:30 a.m. to 5 p.m.

JHU/American Red Cross blood drive. For eligibility require ments, go to www.hopkinsworklife .org/community/blood_drive_ locations.html. To schedule a donation, call 410-550-0289. Francis X. Knott Conference Center.

G RA N D ROU N D S

Bayview

jay vanrensselaer / HOMEWOODPHOTO.JHU.EDU

COLLOQUIA

“Oxidation of Peptides and Proteins by Iron Complexes,” a Chemistry colloquium with Jeremy Kodanko, Wayne State University. 233 Remsen. HW

Tues., Feb. 15, 4:15 p.m.

Wed.,

Feb.

“Short Telomeres and Age-Related Disease,” Pathology grand rounds with Mary Armanios, SoM. Hurd Hall. EB

Mon., Feb. 14, 8:30 a.m.

16,

3:30

p.m.

“Connecting Stellar Explosions to Their Progenitors,” an STSci colloquium with Jose Prieto, Carnegie DTM. Bahcall Auditorium, Muller Bldg. HW “What’s Musicology Got to Do With It?” a Peabody DMA Musicology colloquium with Don Randel, president, the Andrew W. Mellon Foundation. Griswold Hall. Pea-

Wed., Feb. 16, 5 p.m.

body

“The Paragon of Animals: Negotiating Human Nature With Man: A Course of Study,” a History of Science, Medicine and Technology colloquium with Erika Milam, University of Maryland, College Park. 300 Gilman. HW Thurs., Feb. 17, 3 p.m.

“Cartesian Consciousness Reconsidered,” a Philosophy colloquium with Alison Simmons, Harvard University. Co-sponsored by the Templeton Project. 288 Gilman. HW

Thurs., Feb. 17, 4 p.m.

Fri., Feb. 18, 2 p.m. “The Forefathers of Radio,” an Applied Physics Laboratory colloquium with Bob Buus, formerly of Bell Labs. Parsons Auditorium. APL

C O N F ERE N C E Fri., Feb. 18, and Sat., Feb. 19, 9 a.m. to 5 p.m. “Directions of

Realism,” a Humanities Center graduate student conference with keynote speakers Michael Fried, KSAS, and Alex Woloch, Stanford University. 208 Gilman. HW

D I S C U S S I O N / TA L K S

“The Rise of Asian National Oil Companies on Global Oil Markets,” a SAIS Energy, Resources and Environment Program discussion with Mon., Feb. 14, 1 p.m.

Season opener

acrosse is back. The Johns Hopkins women’s lacrosse team opens its 16-game regular season at home with a game against George Mason at 1 p.m. on Saturday at Homewood Field. Juniors Candace Rossi and Alyssa Kildare will lead the 2011 squad. Rossi (in photo above) led the team in goals, assists and points last year and was named Second Team All-ALC (American Lacrosse Conference). Kildare, a First Team All-ALC selection, started all 17 games last season and finished with career highs in ground balls, draw controls and caused turnovers. The Blue Jays finished their 2010 season with a 10-7 record, doubling their win total from a season ago. They lost to the Florida Gators in the ALC Tournament quarterfinals. The men’s lacrosse team will open its 2011 season at noon on Saturday at Towson University. The Blue Jays will be led by co-captains Kyle Wharton, Matt Dolente and Chris Boland. The men’s team hopes to rebound from a disappointing season when they finished with an overall 7-8 record after a loss to Duke in the NCAA Tournament quarterfinals. The men’s home opener will come against Sienna at 1 p.m. on Feb. 26 at Homewood Field. —Greg Rienzi

Willy Haakon Olsen, Statoil. To RSVP, e-mail saisere@jhu.edu or call 202-663-5786. 500 BernsteinOffit Bldg. SAIS Mon., Feb. 14, 3 p.m. Grzegorz Kolodko, Kozminski University, Poland, will discuss his book, Truth, Errors and Lies: The Political Economy of 21st Century Globalization. To RSVP, e-mail transatlanticrsvp@ jhu.edu or call 202-663-5883. Rome Bldg. Auditorium. SAIS

“Crisis in the North Caucasus: Any Way Out?” a SAIS Central Asia-Caucasus Institute panel discussion wth Ilyas Akhmadov, former foreign minister of Chechnya; Glen Howard, Jamestown Foundation; and Andrei Illarionov, CATO Institute. To RSVP, e-mail saiscaciforums@

Tues., Feb. 15, 5:30 p.m.

jhu.edu or call 202-663-7723. Rome Bldg. Auditorium. SAIS Wed., Feb. 16, 12:30 p.m.

“The Natural Gas Revolution: United States and Global Impacts,” a SAIS Energy, Resources and Environment Program panel discussion with Melanie Kenderdine, MIT Energy Initiative; Vello Kuuskraa, president, Advanced Resources International Inc.; and John Quigley, former secretary, Pennsylvania Department of Conservation and Natural Resources. To RSVP, e-mail eregloballeadersforum@ jhu.edu or call 202-663-5786. 500 Bernstein-Offit Bldg. SAIS Wed., Feb. 16, 12:30 p.m.

“The Violent Persecution of Refugees,” a SAIS African Studies

Wed., Feb. 16, 4 p.m. “Science and the World’s Future,” Medical and Biomedical Education grand rounds with Bruce Alberts, editor-in-chief, Science Magazine. Strauch Auditorium East, Armstrong Bldg. EB

L E C TURE S Tues., Feb. 15, 4 p.m. “The Contortions of Forgiveness: Betrayal, Abandonment and Narrative Entrapment Among the Harkis,” an Anthropology lecture by Vincent Crapanzano, CUNY Graduate Center. 400 Macaulay. HW Tues., Feb. 15, 6:30 p.m. The 2011 Percy Graeme Turnbull Memorial Poetry Lecture by Stanley Plumly, director of creative writing, University of Maryland, and former Maryland poet laureate. Mudd Hall Auditorium. HW Wed., Feb. 16, 7:30 to 9 a.m.

Leaders + Legends Lecture— “Transforming Cities Through Smart Mobility: A Leading Transportation Company’s Approach” by Mark Joseph, CEO and vice chairman, Veolia Transportation. (See story, p. 6.) Business attire required. Sponsored by the Carey Business School. Legg Mason Tower, Harbor East. “How America Invented the Humanities,” a Humanities Center lecture by Geoffrey Galt Harpham, president and director, National Humanities Center. 208 Gilman.

ics Laboratory and the Maryland Space Grant Consortium. 272 Bloomberg Center. HW Mon., Feb. 21, 4 p.m. Dean’s Lecture III by Srinivasa Raja, SoM. Sponsored by the Dean’s Office, School of Medicine. Hurd Hall. EB

MUSIC Wed., Feb. 16, 7:30 p.m. The Peabody Wind Ensemble performs woodwind and brass music by Puckett, Crouch, Bayolo, Walton and Mackey. $15 general admission, $10 senior citizens and $5 for students with ID. Friedberg Hall. Peabody Sat., Feb. 19, 7:30 p.m. Peabody Camerata performs music by de Falla, Davis and Adams. Griswold Hall. Peabody

Hopkins Symphony Orchestra presents Aaron Copland’s Suite from Appalachian Spring. $8 general admission, $6 for JHU faculty, staff and alumni, non-JHU students and senior citizens; free for JHU students with valid ID. SDS Room, Mattin Center. HW

Sun., Feb. 20, 3 p.m.

REA D I N G S / B OO K TA L K S

Critically acclaimed authors Jessica Anya Blau and Paula Bomer will read and sign copies of their latest novels, Drinking Closer to Home and Baby and Other Stories. (See In Brief, p. 2.) Barnes & Noble Johns Hopkins. HW Thurs., Feb. 17, 7 p.m.

S E M I N AR S

“Mole cular Basis of Transcription Preinitiation and Initiation by RNA Polymerase II,” a Biological Chemistry seminar with Xin Liu, Stanford University. 612 Physiology. EB

Mon., Feb. 14, noon.

“Prokaryotes Fight Back With a CRISPR Response to Infection,” a Biochemistry and Molecular Biology seminar with Scott Bailey, SPH. W1020 SPH. EB

Mon., Feb. 14, noon.

Mon.,

Feb.

Thurs., Feb. 17, 4 p.m. “Molecular Physiology of the Skeleton,” an Orthopaedic Surgery Research lecture by Stavroula Kousteni, Columbia University. 5152 JHOC. EB

“Lunar Poles—An Ideal Site for Future Exploration,” a NASA Lunar Science Institute lecture by Ben Bussey, APL. First in a series. Cosponsored by the Applied Phys-

Fri., Feb. 18, 1:30 p.m.

12:15

p.m.

Continued on page 9

Wed., Feb. 16, 4 p.m.

14,

“How the Cell Smells: Deficiencies in Primary Cilia Cause Sensory, Neural and Renal Defects and Obesity,” a Carnegie Institution Embryology seminar with Peter Jackson, Genentech. Rose Auditorium, 3520 San Martin Drive. HW

Calendar Key APL BRB CRB EB HW JHOC

(Events are free and open to the public except where indicated.)

Applied Physics Laboratory Broadway Research Building Cancer Research Building East Baltimore Homewood Johns Hopkins Outpatient Center KSAS Krieger School of Arts and Sciences PCTB Preclinical Teaching Building SAIS School of Advanced International Studies SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering