The Gazette -- March 22, 2010 by The Johns Hopkins University

o ur 3 9 th ye ar

C H I N E S E C HORU S

ARRA RE S EAR CH

Covering Homewood, East Baltimore, Peabody,

World-renowned singing group

Scientists to examine how

SAIS, APL and other campuses throughout the

visits Homewood on its tour of

‘mobile DNA’ contributes to

Baltimore-Washington area and abroad, since 1971.

U.S. universities, page 16

genetic diversity, page 9

March 22, 2010

The newspaper of The Johns Hopkins University

F I N A N C E S

G R O U N D S

Homewood’s gardening guru

2010-2011

For Mark Selivan and his crew, the first week of spring is showtime

By Dennis O’Shea

By Greg Rienzi

Homewood

The Gazette

uition for full-time undergraduates at The Johns Hopkins University will increase 3.9 percent this fall, the second consecutive increase below 4 percent. “Johns Hopkins understands that this has been a very difIncrease for ficult time,” President Ronald J. Daniels said, “and we full-time have worked hard undergrads to recognize the challenges faced by many students and will be 3.9 families in a recessionary economy percent while balancing the fiscal challenges confronting the university.” The increase, amounting to $1,530, will bring tuition to $40,680 for the nearly 5,000 full-time undergraduates in the university’s Krieger School of Arts and Sciences and the Whiting School of Engineering. The increase will be the second smallest in percentage terms for those schools in 36 years, since the 1974–75 academic year. The only smaller percentage increase was 3.8 percent this year. The 3.9 percent increase also applies to students in the university’s two smaller schools with full-time undergraduates. The 2010–2011 tuition for more than 340 undergraduate musicians at the Peabody Conservatory will be $35,600, an increase of $1,350. The School of Nursing, with more than 350 full-time undergrads, will increase tuition for students in the traditional track by $1,245, to $33,165. Tuition for the 13-month accelerated track will be $62,223, an increase of $2,336. While holding down tuition, the university has made commitments to continue to build its financial aid budgets. Aid for undergraduates in the Krieger and Whiting schools will increase this fall by 11.3 percent, or $6.2 million, to a total of $61.1 million. Peabody’s aid budget will rise 5 percent, and the Continued on page 14

ark Selivan loves to take time out of his day to smell the roses. To be fair, he gives equal opportunity to the tulips, daffodils, crocuses, magnolias and other colorful blooms that have popped up across the Homewood campus. No surprise that Selivan, the university’s grounds manager, revels in the onset of spring. The native New Englander particularly looked forward to this year’s blossoms. In an effort to inject more color, the grounds crew had planted new flower beds all across the campus. The result will be a potpourri of yellows, pinks, creamy whites, lavenders and other pastels. When he applied his brush strokes, Selivan made sure to heavily populate the campus with native species such as black-eyed Susans, viburnums, Shasta daisies and others as part of his overall effort to craft a beautiful but easy-tomaintain campus. His work has been noticed. In response to Johns Hopkins’ “snub” on Forbes magazine’s recent “World’s Most Beautiful College Campuses” list, The Chronicle of Higher Education last week placed Homewood on its unofficial “Most Beautiful Campuses One Never Continued on page 7

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Tuitions are set for

Volume 39 No. 26

Grounds manager Mark Selivan and his 12-member crew tend to the flowers, shrubs, trees and lawns of Johns Hopkins’ 140-acre Homewood campus.

F A C I L I T I E S

Public Health awarded $15 mill for lab renovations By Tim Parsons

School of Public Health

he Johns Hopkins Bloomberg School of Public Health will receive nearly $15 million from the American Recovery and Reinvestment Act for renovation and modernization of laboratory space at its main facility at 615 N. Wolfe St.

In Brief

Licensing agreement; Alternative Spring Break; ‘King of the Lobby’ author lunch

The grant was awarded by the National Center for Research Resources, part of the National Institutes of Health. The renovation includes updating labs and new infrastructure in the 45-year-old Hume Wing, located on the building’s north side along Monument Street. The nine-story wing was built in 1964 and houses 25 percent of the school’s research laboratories. “The school’s legacy has and continues to

Calendar

Templeton Research Lectures; historian Niall Ferguson; social media discussion

be one of translating research into strategies to improve the public’s health throughout the world. This renovation project is key to allowing our investigators to remain competitive for future research projects and to maintain the school’s ability to recruit highcaliber scientific talent,” said Michael J. Klag, dean of the Bloomberg School. “Most Continued on page 5

14 Job Opportunities 14 Notices 15 Classifieds

2 THE GAZETTE • March 22, 2010 I N B R I E F

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NeuroTranslational Program inks licensing agreement

ohns Hopkins’ newly formed Brain Science Institute’s NeuroTranslational Program has entered into a licensing agreement with pharmaceutical company Eisai to discover and develop small molecule glutamate carboxypeptidase II, or GCPII, inhibitors. The NeuroTranslational Program was launched in 2009 and staffed with seasoned drug-discovery scientists to work with Johns Hopkins faculty to help translate basic science discoveries into small molecule therapeutics. “It is a great accomplishment for this team to announce a licensing agreement of this kind within its first year of operation,” said Jeffrey Rothstein, professor of neurology in the School of Medicine and co-director of the program. Under the terms of the agreement, Eisai has granted the BSI nonexclusive U.S. rights to use its GCPII technology to generate inhibitor molecules for diseases of the central and peripheral nervous system— including peripheral neuropathy and neurodegeneration, Alzheimer’s disease, stroke and ALS—as well as non-central nervous system diseases. BSI will be responsible for the GCPII research, drug discovery and preclinical activities; Eisai will have an exclusive option to develop and commercialize any drug molecules generated from the collaboration, which will be led by a joint steering committee of representatives from both entities. Barbara Slusher, chief scientific officer of the NeuroTranslational Program, will serve as the academic lead of the steering committee, along with Takashi Tsukamoto, the program’s director of medicinal chemistry.

Undergrads’ spring break is in Baltimore and Washington

ancun? How about a good cause instead. Once again, some Johns Hopkins undergraduates spent a portion of their vacation on Alternative Spring Break, a seven-day event hosted by the Homewood campus’s Center for Social Concern. Last year, the CSC and SOURCE—the Student Outreach Resource Center that serves the schools of Medicine, Nursing and Public Health—collaborated to provide students with an opportunity to participate in a service-based spring break in Baltimore. The inaugural four-day event included activities that allowed participants to explore the city, learn about social issues and have some fun in the process. This year, the event was expanded to include trips, activities and volunteer service in both Baltimore and Washington, D.C. The program, which focused on food justice and poverty, included a day of service at D.C. Central Kitchen and a discussion

E d i to r Lois Perschetz Writer Greg Rienzi

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with its founder, volunteering at Baltimore’s Great Kids Farm, a visit to the Maryland Food Bank and meeting a member of Baltimore City’s Health Department. The itinerary also included dinners, movies and other social activities. Alternative Spring Break ran from March 13 to 19.

Nursing deploys second team to Haiti, raises funds for relief

second team of Johns Hopkins Nursing faculty, graduate students and alumni, and non-Hopkins nurses, has left for Haiti on a two-week deployment. This team follows closely on the steps of colleagues who departed on March 5 to assist in the relief efforts following the country’s devastating earthquake. Elizabeth “Beth” Sloand, an assistant professor in the School of Nursing, coordinated the groups. Fund-raising efforts by School of Nursing students, faculty and staff have reached $3,000 and continue at the school with a Clothing Swap/Sale from 11 a.m. to 6 p.m. on Tuesday, March 23.

Johns Hopkins Hospital earns 2010 Hospital of Choice Award

he Johns Hopkins Hospital has received a 2010 American Alliance of Healthcare Providers’ American Hospital of Choice Award. The award, the seventh for which Johns Hopkins has been selected since the recognition’s inception in 2002, is designed to find America’s most customer-friendly hospitals, based either on an extensive application process or by a review of a facility’s public communication and staff interaction with customers. Of the approximately 400 hospitals that AAHCP evaluates each year, 10 are recognized with the Hospital of Choice Award.

JHU Press author to discuss ‘King of the Lobby’ at luncheon

HU Press author Kathryn Allamong Jacob will discuss her book King of the Lobby in the Press’ lunch and lecture series at 12:30 p.m. on Tuesday, March 23, at the Johns Hopkins Club. In her new book, Jacob tells the story of how Sam Ward earned his “crown” by creating a new type of lobbying—social lobbying—that remains an essential feature of life in Washington, D.C. Jacob will talk about how, through cookery and conversation, this scion of an honorable old family, brother of unassailably upright Julia Ward Howe, best friend of Henry Wadsworth Longfellow and California ’49er became the most influential lobbyist of the Gilded Age. Admission is $20. Johns Hopkins Club members should contact the club to make reservations; nonmembers should contact Jack Holmes at 410-516-6928 to attend as a Friend of the Press.

Contributing Writers Applied Physics Laboratory Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Katerina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Government, Community and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: gazette@jhu.edu Classifieds e-mail: gazads@jhu.edu On the Web: gazette.jhu.edu Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 410343-3362 or gazellegrp@comcast.net.

March 22, 2010 • THE GAZETTE

E V E N T

SoM to host ‘A Tribute to 150+ Women Professors’ celebration By Stephanie Desmon

Johns Hopkins Medicine

lorence Sabin, the famed pathologist, became the first woman given the title of full professor at the Johns Hopkins University School of Medicine, in 1917. The second female professor wasn’t named until more than 40 years later. And when Janice Clements was promoted in 1990, she was only the 24th woman in the nearly 100year history of the medical school to make full professor. Times have changed. On Thursday, March 25, the School of Medicine will mark the passage of a major milestone in gender equity with a celebration of the great strides made by the institution—and the women in the institution— over the past two decades. The event, to be called “A Tribute to 150+ Women Professors,” will take place at 4 p.m. at the Turner Auditorium on the East Baltimore campus. “We’ve put an emphasis on this, and it has really paid off,” said Clements, vice dean for faculty and a professor of comparative medicine. “Medicine was a very maledominated field until about 15 years ago,” she said. “Even if women got into medicine, if you looked around at the leadership, you didn’t see women. Without role models, it was impossible to think, ‘That’s what I want to do.’ Now they are starting to have role models who look like them.” Edward Miller, dean of the School of Medicine and CEO of Johns Hopkins Medicine, said, “When we encourage women to advance in their careers at Hopkins, great things happen. We cannot permit the wealth of talent within our female faculty to go untapped. It is not only in the best interests of our female faculty to advance through the ranks, it is in our institution’s and our patients’ best interests as well.” Women make up about 20 percent of the professors at the School of Medicine, Clements says, a number that puts Johns Hopkins ahead of the curve nationally. Only about 15 percent of the professors at academic medical centers nationwide are women. The proportion of female associate professors at Johns Hopkins is about 35 percent, and the proportion of female assistant professors is about 45 percent. Medical school classes are 50-50, she says. “We’re building the pipeline,” she said. “Our goal is to eventually have the percentage of female professors be something like 40 percent to 50 percent.”

As part of the March 25 tribute, Clements will present the Vice Dean’s Award for the Advancement of Women Faculty to Emma Stokes, director of Priority Initiatives for the Department of Medicine. Among those scheduled to speak at the event are Carol Greider, winner of the 2009 Nobel Prize in physiology or medicine for her pioneering work in telomeres and the Daniel Nathans Professor and Director of Molecular Biology and Genetics at Johns Hopkins. Greider became one of just a handful of women to ever win the Nobel in that category. Also on the agenda: Barbara Migeon, the geneticist who became female professor No. 6 in 1978, and Patti Vining, a professor of neurology since her promotion in 2002. Also addressing the group will be Professor No. 150: Kristy Weber, who, when she became a professor of orthopedic surgery and oncology last summer, became the first woman in the history of Johns Hopkins’ Department of Orthopaedic Surgery to be promoted to professor. Weber graduated from the Johns Hopkins School of Medicine in 1991 and was recruited back to the university in December 2003 to build the Musculoskeletal Oncology Program. Her focus is on bone and soft-tissue cancers. She sees patients, performs surgery and does research on metastatic cancer in the bone. Ever humble, she downplays her role as a pioneer, calling her spot as No. 150 “the luck of the draw.” When pathologist Barbara Detrick was promoted earlier this year, she became the 155th woman to become a full professor. Only about half the women who have earned the title at Johns Hopkins remain on the faculty. Some have died or retired; others have gone on to leadership roles at other institutions. When Johns Hopkins’ medical school was founded in 1893, it was the first major medical school to admit women on an equal basis with men, thanks to the efforts of philanthropist Mary E. Garrett, who endowed the school on that stipulation. “For those early women professors, I don’t know how they did it. The environment must have been very tough for women,” Weber said. There are stereotypes that may scare off women, she says, particularly in surgery, where patients and fellow doctors often expect a man to be performing the operations. Add in the long hours [and] the desire for many women to have families and balance in their lives, and it makes for

Homewood memorial service set for M. Gordon ‘Reds’ Wolman

memorial service will be held on Sunday, April 11, on the Homewood campus to celebrate the life of M. Gordon “Reds” Wolman, an internationally respected expert in river science, water resources management and environmental education. Wolman, an important and beloved member of The Johns Hopkins University faculty for more than half a century, died Feb. 24 at age 85. The memorial event, beginning at 1 p.m. in a tent outside the Homewood Museum, will honor Wolman for his research contributions, his mentorship to generations of students and his long record of service to the university. At the time of his death, he was the B. Howell Griswold Professor of Geography and International Affairs in the Department of Geography and Environmental Engineering. Among those scheduled to pay tribute to Wolman are Ronald J. Daniels, president of the university; Nicholas Jones, the Benjamin T. Rome Dean of the Whiting School of Engineering; Edward Bouwer, the

Abel Wolman Professor of Environmental Engineering and chair of the Department of Geography and Environmental Engineering; and a number of Wolman’s colleagues, former students and friends. All are welcome to attend. Free parking will be available in the South Garage, and shuttles will be provided to and from the service. Organizers of the event are planning two tributes incorporating the river rocks for which Wolman was so well-known. One, to be called “The Meander,” will be an installation built from stones provided by those who knew Wolman; the other involves attendees scattering pebbles into their favorite rivers. Details are posted online at http://eng.jhu .edu/wse/Reds_wolman/memorial-service. Gifts in honor of Wolman will be used to establish the M. Gordon Wolman Fellowship, a graduate student fellowship that will reflect Wolman’s impact across the department, the school and the university. Gifts to this fund may be made by calling 410-5168723 or by going to https://jhweb.dev.jhu .edu/eforms/form.do?formId=10462.

a difficult equation for many. Weber says that her goal is to “be visible and erase any stereotypes that are untrue.” “Women have a different approach to patients, and I think some patients are looking for women to be their doctors,” she said. “Some of my women patients are happy to have a woman surgeon. They feel comforted.” Clements says that efforts large and small have been made to bring in women and encourage them to stay at Johns Hopkins. She recalls that when she was asked to give the prestigious Dean’s Lecture in the early 1990s, she was the first woman to do so. Now, the lectures are given every year by two men and two women from the faculty. Clements says that more attention has been paid in recent years to positioning women to be promoted. Forty-five women have become full professors since 2005. Assistant and associate professors now get annual reviews with the heads of their departments or divisions— the perfect place, she says, to discuss the path to full professorship. Johns Hopkins recently created the Office of Women in Science and Medicine to assist women in advanc-

ing their careers. Efforts have been made to ensure gender equity in salaries. And some of the “crazy” hours required of doctors have been scaled back in family-friendly ways. In surgery, for example, grand rounds used to be done at Johns Hopkins on Saturday mornings, something that turned off many women considering the university. Now grand rounds are during the week. Still, progress is slower than some would like. There are, for example, only three department heads at the School of Medicine who are women, including Julie Ann Freischlag, who chairs Surgery. “When you make a place better for women, you make it better for all faculty,” Freischlag said. So much is expected of women beyond what happens during the workday, Clements says. “We don’t just do our professional careers; we do all of the other things we feel responsible for,” she said. “That complicates and makes the road a little bit harder. We take care of our children and take care of our extended families. There are all of those other expectations.”

Nursing students use IT to improve global health B y H i l l e l K u tt l e r

School of Nursing

he Johns Hopkins School of Nursing’s technology-driven Web platform for exchanging health information worldwide has tapped into a valuable source of innovation: the informatics-savvy student body. In the fall 2009 Information Technology in Nursing course, the school’s 130 students produced low-bandwidth digital modules for conveying vital health information to nurses and others who work in medically underserved communities here and abroad. The projects target such diverse health imperatives as preventing HIV/AIDS among Bangladeshi sex workers and rickshaw drivers, improving prenatal care among Hispanic-Americans and addressing pediatric gastrointestinal conditions and halting the spread of swine flu in China. Although filled with valuable information and presented attractively, the projects are digitally modest by design to account for the recipients’ low-bandwidth capabilities. The student-led projects were developed as podcasts, freely accessible multimedia online lectures and radio broadcasts, many in the language of the target audience. The student projects will be distributed on the school’s Global Alliance for Nursing and Midwifery Electronic Community of Practice, a Web platform that allows health professionals to exchange knowledge even in areas with low bandwidth. At present, 2,000 nurses, midwives and community health workers from 140 different countries are interacting in the GANM. Patricia Abbott, co-director of the school’s Collaborating Center for Knowledge, Information Management and Sharing, said that the nursing students’ educational projects reflect the school’s commitment to “new-world education” and dramatically demonstrate that “it’s not your mother’s nursing anymore. It’s about turning these young students loose

and saying, What solutions can technology offer with low-resource places in mind?” she said, calling the results “humbling and inspiring.” “The way our students are critically thinking and applying ‘new ways of doing’ with technology gives me great hope for the future,” she said. Megan Flora, who worked on a Spanish-language slide show targeted to Hispanic-American expectant mothers, said that the exercise taught her “the importance of tailoring your information to the specific patient, knowing about their culture and population” and avoiding “a one-size-fits-all” presentation. “Thinking about innovative uses of technology to reach and teach has been eye-opening,” she said. For Shehzin Mozammel, producing a slide show for nurses in her native Bangladesh complements the country’s effort to stem the spread of HIV/AIDS. Her group’s presentation, which is partially in the Bengali language, includes such basic instruction as how to properly use a condom. “By using the education I’ve gained in North America, I can educate my own people and explain the situation to them. Bangladeshis really admire people who have left … and want to give back,” Mozammel said. “I’m very excited about this. If this is one way I can give back, it’s a start. I’m only one person, but I truly feel like I can make an impact, even a revolution. If I can teach people about sexually transmitted infections, it can make an impact.” Instructor Krysia Hudson, who cotaught the class with Abbott and Beth Kilmoyer, said that her students’ projects will deliver reliable information where it’s most needed. “Putting a disease in the context a consumer can use is really very useful,” she said. “It also gets our students’ feet wet in developing applications that will be used. Our students want to make a difference, and with interactive and digitally distributable knowledge, they are seeing this come to life.” Added Abbott, “What a difference from a dust-collecting term paper.”

4 THE GAZETTE â&#x20AC;˘ March 22, 2010

Independent public health evaluations could save lives Study recommends improvements for scaling up child survival programs

ew child survival programs must engage evaluation teams from the start to identify the major causes of child mortality in intervention areas and to ensure that appropriate resources are available to scale up coverage and treatment, according to a retrospective evaluation led by researchers at the Johns Hopkins Bloomberg School of Public Health. The studyâ&#x20AC;&#x201D;the first in a series of articles to focus on evidence from large-scale evaluationsâ&#x20AC;&#x201D;appeared in the Jan. 16 issue of the

Lancet and is available online. The new recommendations will help governments and donor agencies invest new funding to avert childhood deaths and reach the United Nations Millennium Development Goals. â&#x20AC;&#x153;The best medicine is worthless if it doesnâ&#x20AC;&#x2122;t reach the patient,â&#x20AC;? said lead author Jennifer Bryce, a senior scientist with the Bloomberg Schoolâ&#x20AC;&#x2122;s Department of International Health. â&#x20AC;&#x153;This analysis of realworld situations offers concrete guidelines for program implementation at scale that, if heeded, can save childrenâ&#x20AC;&#x2122;s lives.â&#x20AC;? Researchers evaluated the Accelerated Child Survival and Development Program, which was implemented by UNICEF in 11 West African countries between 2001 and 2005. The evaluation was limited to

focus areas in Benin, Ghana and Mali, where ACSD worked to deliver a full set of interventions. The study used data from the Demographic and Health Surveys and Multiple Indicator Cluster Surveys to compare changes in coverage for 14 ACSD interventions, nutritional status (stunting and wasting) and mortality in children younger than 5 years in the ACSD focus districts with those in the remainder of every country (comparison areas). â&#x20AC;&#x153;The studyâ&#x20AC;&#x2122;s insights and recommendations are applicable to a variety of national and multinational child survival interventions and can ultimately save lives if adopted by funding agencies and ministries of health,â&#x20AC;? added Cesar Victora, a visiting professor in the Department of International Health.

â&#x20AC;&#x2DC;Keeping up with the neighborsâ&#x20AC;&#x2122; speeds vaccine use Other countriesâ&#x20AC;&#x2122; policies are factors in decision to implement Hib vaccine By Tim Parsons

School of Public Health

esearchers at the Johns Hopkins Bloomberg School of Public Health conducted an analysis of worldwide use of Haemophilus influenza Type b vaccine, or Hib, to determine what factors influenced a nationâ&#x20AC;&#x2122;s adoption of the vaccine. The study found that a nationâ&#x20AC;&#x2122;s eligibility for support from the Global Alliance for Vaccine and Immunization, also known as GAVI, and whether a countryâ&#x20AC;&#x2122;s neighbors used the vaccine were major influencing factors in addition to price of the vaccine. The

findings appear in the March 16 edition of PLoS Medicine. â&#x20AC;&#x153;This study is the first to measure how countriesâ&#x20AC;&#x2122; decisions to adopt new vaccines are highly influenced by their neighborsâ&#x20AC;&#x2122; decisions,â&#x20AC;? said the studyâ&#x20AC;&#x2122;s lead author, Jessica Shearer, a former research associate at the Bloomberg School. â&#x20AC;&#x153;Countries seem to be engaging in an arms race to vaccinateâ&#x20AC;&#x201D; decisions which will save millions of lives.â&#x20AC;? For the study, the researcher analyzed data on Hib use from 147 countries from 1990 to 2007. Models were developed to account for a nationâ&#x20AC;&#x2122;s income and burden of Hib disease. According to the study, the receipt of GAVI support sped up the time on decisions to use Hib by 63 percent. The presence of two or more neighboring countries using Hib accelerated adoption by 50 percent. An increase in price negatively affected the time it took a country to adopt Hib vaccine, a finding that substantiated those of previous studies.

Added Shearer, â&#x20AC;&#x153;While high vaccine prices hinder adoption, the absence of long-term, stable financing policies at the global level had an even more detrimental effect.â&#x20AC;? The World Health Organization estimates that 2.1 million people died worldwide in 2002 due to vaccine-preventable diseases. David Bishai, senior author of the study and an associate professor in the Bloomberg Schoolâ&#x20AC;&#x2122;s departments of Population, Family and Reproductive Health and of International Health, said, â&#x20AC;&#x153;GAVI has been hoping to accelerate the speed at which poor countries get access to life-saving vaccines. This study shows how successful these efforts have actually been.â&#x20AC;? Additional authors of the study are Meghan L. Stack, Marcie Richmond, Allyson P. Bear and Rana A. Hajjeh. The research was funded by the Hib Initiative, which receives funding from the GAVI Alliance.

The analysis showed that child survival was not accelerated in Benin and Mali focus districts because coverage for effective treatment interventions for malaria and pneumonia were not accelerated, causes of neonatal deaths and undernutrition were not addressed, and stock shortages of insecticide-treated nets restricted the potential effect of this intervention. The authors used these findings to develop four recommendations for future programs: â&#x20AC;˘ Active promotion of country policies supporting community case management for pneumonia and malaria, and the incorporation of zinc into the management of diarrhea â&#x20AC;˘ Incorporation of simulation models to estimate potential lives saved into program planning exercises nationally to ensure that decision-makers have access to up-todate information about local causes of child deaths and reliable evidence for intervention effectiveness â&#x20AC;˘ Definition and implementation of stronger compensation, motivation and supervision approaches for community-based workers â&#x20AC;˘ Strengthening the nutrition component of country programs â&#x20AC;&#x153;As investment to reach Millennium Development Goals grows, implementation research becomes increasingly important,â&#x20AC;? said co-author Robert E. Black, professor and chair of the Department of International Health. â&#x20AC;&#x153;This study commissioned by UNICEF and CIDA shows how independent evaluations can maximize funding and ultimately save lives.â&#x20AC;? The study was written by Bryce, Kate Gilroy, Gareth Jones, Elizabeth Hazel, Black and Victora. UNICEF, the Canadian International Development Agency, Coordenacao de AperfeiĂ§oamento de Pessoal do NĂvel Superior (Brazil) and the Fulbright Fellowship provided funding for the evaluation. â&#x20AC;&#x201D;Tim Parsons

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March 22, 2010 • THE GAZETTE

Why symptoms of schizophrenia emerge in young adulthood

n reports of two new studies, a Johns Hopkins–led research team says it has identified the mechanisms rooted in two anatomical brain abnormalities that may explain the onset of schizophrenia and the reason symptoms don’t develop until young adulthood. Both types of anatomical glitches are influenced by a gene known as DISC1, whose mutant form was first identified in a Scottish family with a strong history of schizophrenia and related mental disorders. The findings could lead to new ways to treat, prevent or modify the disorder or its symptoms. In one of the studies, published in the March issue of Nature Neuroscience, researchers examined DISC1’s role in forming connections between nerve cells. Numerous studies have suggested that schizophrenia results from abnormal connectivity. The fact that symptoms typically arise soon after adolescence, a time of massive reorganization of connections between nerve cells, supports this idea. The scientists began their study by surveying rat nerve cells to see where DISC1 was most active. Unsurprisingly, they found the highest DISC1 activity in connections between nerve cells. To determine what DISC1 was doing in this location, the researchers used a technique called RNA interference to partially shut off DISC1 activity. Consequently, they saw a transient increase and eventual reduction in size and number of dendritic spines, spikes on nerve cells’ branchlike extensions that receive input from other nerve cells. To determine how DISC1 regulates dendritic spine formation, the researchers studied which brain proteins interact with the protein expressed by the DISC1 gene. They

identified one, called Kal-7, which earlier studies suggested is critical for proper dendritic spine formation. Further experiments suggested that the DISC1 protein acts as temporary holding place for Kal-7, binding it until it can be released to trigger a molecular cascade that results in dendritic spine formation. Study leader Akira Sawa, professor of psychiatry and director of the Program in Molecular Psychiatry at the Johns Hopkins School of Medicine, says it is becoming clear that having a defective DISC1 gene might lead to an abnormally small number and size of dendritic spines, which could cause nerve cells to maintain weaker connections with unusually low numbers of neighboring neurons. Such abnormal connectivity has long been seen in autopsied brains from schizophrenia patients. “Connections between neurons are constantly being made and broken throughout life, with a massive amount of broken connections, or ‘pruning,’ happening in adolescence,” Sawa said. “If this pruning doesn’t happen correctly, it may be one reason for the pathogenesis of schizophrenia.” In the second study, published in the Feb. 25 issue of Neuron, Sawa’s team generated a new animal model of schizophrenia by temporarily shutting off the DISC1 gene in mice in the prefrontal cortex, a brain area known to differ in schizophrenic people. The new model allowed them to study other roles for DISC1 in the brain. The researchers created their novel model by again using RNA interference. They injected short pieces of the nucleic acid RNA engineered to shut off the DISC1 gene into cavities in the developing brains of mouse fetuses two weeks after conception. Tests showed that these snippets of RNA

Tournées Festival of Contemporary French Cinema debuts at Homewood

March 24, 7:30 p.m., 26 Mudd Hall. The Class (Entre les murs), dir. Laurent Cantet (2008). March 25, 7:30 p.m., 26 Mudd Hall. Terror’s Advocate (Avocat de la terreur), dir. Barbet Schroeder (2007). Presented by Marc Caplan, Jewish Studies and AnneGaëlle Saliot of German and Romance Languages and Literatures. March 26, 7:30 p.m., 205 Krieger Hall.

The Witnesses (Les Témoins), dir. André Techiné (2007).

March 30, 7:30 p.m., 110 Maryland Hall. Frantz Fanon: His Life, His Struggle, His Work (Frantz Fanon: Sa vie, son combat, son travail), dir. Cheik Djemai (2004). March 31, 7:30 p.m., 26 Mudd Hall.

The Beaches of Agnès (Les Plages d’Agnès), dir. Agnès Varda (2008). April 1, 7:30 p.m., 101 Remsen

Hall. Lady Chatterley director’s cut, dir. Pascale Ferran (2006).

Continued from page 1 importantly, this project will help ensure that the Bloomberg School of Public Health continues to pioneer discoveries that promote the public’s health, both now and in the future.” Planning and design for the new space are already under way, with construction expected to start in late summer 2011. The renovations will include interior demolition,

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Schedule of screenings

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new mechanical and electrical systems, new laboratory casework and equipment, and interior finishes. The construction will be phased in to allow ongoing research to continue without interruption. Founded in 1916, the Johns Hopkins Bloomberg School of Public Health is the world’s oldest and largest independent school of public health, with more than 2,000 students from 78 countries and more than 1,100 full- and part-time faculty, as well as 3,000 employees. It receives approximately 20 percent of all federal research funds awarded to the 43 accredited schools of public health in the United States. G

Related Web sites

Advocate, an award-winning documentary about Jacques Vergès, a controversial lawyer and hero of the French Resistance— married to a heroine of the struggle for Algerian independence—who defended the Nazi war criminal Klaus Barbie. On Friday, Les Témoins (The Witnesses), André Techiné’s fictional account of the beginnings of the AIDS epidemic in 1980s France, with Michel Blanc, Emmanuelle Béart and Julie Depardieu, will be shown. The second week of the festival will feature Cheik Djemai’s Frantz Fanon: His Life, His Struggle, His Work and The Beaches of Agnès, the acclaimed autobiographical documentary by Agnès Varda, the mythic grandmother of the New Wave. The festival will culminate with the screening of the rarely seen director’s cut of Pascale Ferran’s Lady Chatterley. All films will be in French with English subtitles; see sidebar for times and locations. The Tournées Festival was made possible with the support of the Cultural Services of the French Embassy and the French Ministry of Culture.

DISC1 gene, cause problems that start before birth but surface only in young adulthood. “If we can learn more about the cascade of events that lead to these anatomical differences, we may eventually be able to alter the course of schizophrenia. During adolescence, we may be able to intervene to prevent or lessen symptoms,” Sawa said. Other Johns Hopkins researchers who participated in the Nature Neuroscience study are Akiko Hayashi-Takagi, Manabu Takaki, Saurav Seshadri, Yuichi Makino, Anupamaa J. Seshadri, Koko Ishizuka, Jay M. Baraban and Atsushi Kamiya. Other Johns Hopkins researchers who participated in the Neuron study are Minae Niwa, Kamiya, Hanna Jaaro-Peled, Seshadri, Hideki Hiyama and Beverly Huang. —Christen Brownlee

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ednesday, March 24, marks the beginning of the first Tournées Festival of Contemporary French Cinema at Johns Hopkins. The festival, to be held over two weeks on the Homewood campus, will be launched with a screening of The Class (Entre les murs), Laurent Cantet’s cinéma vérité–style story about a junior high school in a tough Paris neighborhood, which won the grand prize at the 2008 Cannes Film Festival. The screening will be followed by a panel discussion with students from Baltimore public high schools; Jason Hartling, principal of Northwestern High School; Edmund Mitzel, principal of Pikesville High School; Matt Porterfield, a director and Johns Hopkins faculty member, whose film Putty Hill just premiered at the Berlin Film Festival; and Kristin Cook-Gailloud, director of the university’s French language program. The panel will be led by Bernadette Wegenstein, a documentary filmmaker and faculty member at Johns Hopkins. The festival’s first week continues on Thursday with Barbet Schroeder’s Terror’s

migrated into cells in the prefrontal cortex, part of the brain located near the forehead. This shutoff was temporary, with the gene’s function fully restored within three weeks, or about a couple of weeks after birth. At various times after the gene was reactivated, the scientists examined the animals’ brains and behavior, looking for differences from normal mice. Sawa’s team found that in the DISC1 shutoff group, nerve cells in the prefrontal cortex that produce dopamine, one of the chemical signals that nerve cells use to communicate, were markedly immature as the animals entered adolescence. Furthermore, the animals showed signs of a deficit of interneurons, nerve cells that connect other neurons in neural pathways. They also found several behavioral differences between these mice and normal mice as the animals entered adolescence. For example, those in the shutoff group reacted more strongly to stimulants, displaying more locomotion than normal mice. Interestingly, these effects were somewhat mitigated when the researchers gave the animals clozapine, a drug used to treat schizophrenia. Taken together, Sawa says, results of both studies suggest that these anatomical differences, which seem to be influenced by the

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6 THE GAZETTE • March 22, 2010

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March 22, 2010 • THE GAZETTE H O P K I N S

H I S T O R Y

The price tag of federal research support at SoM By Ross Jones

Special to The Gazette

he Johns Hopkins University School of Medicine has been receiving federal support for research for many decades. Faculty and deans of the school, and university presidents and trustees, have been interested in this source of financial support just as long. On Dec. 9, 1936, President Isaiah Bowman informed the trustees about three federally supported projects at the School of Medicine. This is part of an occasional series of historical pieces by Ross Jones, vice president and secretary emeritus of the university. A 1953 graduate of Johns Hopkins, he returned in 1961 as assistant to president Milton S. Eisenhower and was a close aide to six of the university’s 13 presidents.

Guru Continued from page 1 Sees on Lists of Most Beautiful Campuses” list, noting its spruced-up grounds and green space additions. Selivan joined Johns Hopkins in August 2006 and brought with him a conservative, environmentally friendly landscape philosophy that attempts to maximize Nature’s own defenses and resiliency yet not sacrifice good looks. In his first year, he overhauled the existing plant health care plan for the campus and revamped the approach to tending trees and shrubs. Of note, he took an already strong irrigation system and made it even more dynamic. He appointed Robert Stafford as irrigation manager, or “Dr. Hydraulic,” as

He described a joint enterprise of the departments of Pediatrics and Obstetrics. Amos U. Christie, a pediatrician, was interested in issues related to premature infants and had sought support from the Children’s Bureau of the Department of Labor for “an intensive study of metabolism.” The grant, amounting to approximately $7,000, would help provide for Christie’s salary as well as that of his assistant, Marian I. Hedwin. They would be paid directly by the Labor Department. About the same time, Edwards A. Park, Department of Pediatrics, wanted to investigate “X-ray changes in the bones of children with rickets.” Again, the Children’s Bureau was the source of support. The funds provided for the salary of a technician, Deborah Jackson, at $2,000 a year, and the salary of a medical artist “not to exceed $1,600 a year, and a small amount of laboratory equipment.” A division called the Pediatric Cardiac Clinic was financed in part by the trustees of

the Harriet Lane Home. It also received funding from the Office of Child Hygiene of the U.S. Public Health Service. Bowman reported that the total amount of support for the Cardiac Clinic from the Public Health Service in 1936–37 would be about $5,000. “Of this sum,” he said, “$3,200 is paid to Dr. Helen B. Taussig, physician in charge, and about $540 to Dr. Hecht, a part-time physician.” Bowman’s report is now in the Hamburger Archives of the Eisenhower Library. A few historical footnotes on some of the researchers involved: Christie left Johns Hopkins and, in 1943, became chair of the Department of Pediatrics at Vanderbilt University. He focused much of his research on histoplasmosis, which is caused by a fungus and clinically simulates tuberculosis. While an undergraduate at the University of Washington, he had played football for the Huskies in the 1924 Rose Bowl (tied Navy, 14-14).

Park joined the Johns Hopkins faculty in 1912 and left in 1921 to found the Department of Pediatrics at Yale University. He returned to Johns Hopkins in 1927 to become professor of pediatrics and pediatrician in chief of the Harriet Lane Home. He retired in 1946 after creating the divisions of Cardiology, Endocrinology, Neurology and Psychiatry in the Department of Pediatrics. Taussig, who received her medical degree from Johns Hopkins in 1927, is known as the founder of pediatric cardiology for her innovative work on “blue baby” syndrome. In 1944, she and Johns Hopkins surgeon Alfred Blalock and surgical technician Vivien Thomas developed an operation to correct the congenital heart defect that causes the syndrome. She was the recipient of many awards, including the Lasker Award and the Medal of Freedom presented by President Lyndon Johnson in 1964.

Selivan likes to call him. “He is a walking CPU when it comes to our operations and needs for water,” Selivan said. Now in use throughout the campus are hidden spouts that sense when the soil needs moisture and disperse just the amount needed to keep the lawns, plants and trees healthy. Selivan also instituted a new pest management system that breaks the campus into zones, with a grounds-crew member assigned to each. If a problem is spotted, a horticulturist or turf specialist will be called in to diagnose and treat it if necessary, and even then using only low-threshold, low-impact pesticides. Selivan also lauds the work of Richard Gutberlet, the university horticulturalist, who brought 20-plus years of design and growth experience with him to Johns Hopkins. “Rich and Brian form with myself a triad of horticultural power and knowledge that

has made this growing feat of Hopkins a success,” he said. The 12-member grounds crew takes extra care to prune, feed and mulch correctly. Like a person who eats right and gets plenty of exercise, well-cared-for plants and trees are healthier and more resistant to diseases, Selivan says. “We encourage the plants and soil to work for us. In everything we do, we want to be more responsible and more caring of the environment,” says Selivan, who walks the grounds each day to inspect his handiwork. “That means not overfertilizing, like some do, to get those nuclear-green lawns, or [not] bringing in plants that look good on paper but require an inordinate amount of care.” Prior to joining Johns Hopkins, Selivan worked for SavATree, a New England–based tree, shrub and lawn care company. In his work as its regional operations manager and resident arborist, he had several VIP clients, including Martha Stewart. Selivan enjoyed his time with SavATree, he says, but eventually grew weary of the travel and wanted to figuratively and literally plant his roots somewhere else. The job opened up at Johns Hopkins, and in his interview, he says, he immediately hit it off

with David Ashwood, Homewood’s director of plant operations. “David and I share a similar mentality when it comes to grounds keeping,” Selivan says. “We want it to look good, but do so with minimal fuss and minimal environmental impact.” Although he’s in charge of the entire 140acre campus, Selivan still dons his tree-doctor scrubs on occasion to, for example, inject hypodermic needles into at-risk trees or hook up IVs for others. “We treat them from the inside out,” he says. “It’s yet another way to reduce the amount of product exposed to the rest of the environment.” New plant beds include those in front of the Terrace Court Cafe, on the east side of Mason Hall and several in the upper and lower quads. In keeping with the pedestrian nature of the campus, the bed sizes were minimized to not invite trampling. Likewise, Selivan often chooses tougher species that can withstand some of the daily wear and tear of a college campus. Not that he takes kindly to crushed flowers or torn-up turf. “That’s definitely a sore spot for me,” says Selivan with a smile. “But it comes with the territory.” G

Broholm of KSAS wins Neutron Scattering Society research award By Lisa De Nike

Homewood

ollin Broholm, the Gerhard H. Dieke Professor in the Henry A. Rowland Department of Physics and Astronomy at Johns Hopkins, has won the Neutron Scattering Society of America’s 2010 Sustained Research Prize for outstanding studies of correlated electron physics in magnets, metals and superconductors, as well as for the development of neutron scattering techniques. According to the NSS, Broholm was selected for the $2,500 award because of his research’s “enduring impact on science.” Broholm specializes in experimental condensed matter physics, particularly superconductivity, and quantum magnetism and their interplay. He is an expert in the use of neutrons to probe such materials. Neutron scattering involves using beams of neutrons (neutral particles released from atomic nuclei through fission) to analyze materials at the atomic and molecular level. As they scatter from carefully prepared samples, neutrons probe the structure and atomic-scale motion underlying technologically useful materials properties, including magnetism and superconductivity. Invented in North America in the 1950s, neutron scattering is becoming an essential tool in a wide range of materials science projects. Broholm recently was the principal investigator on a project to design and build a revolutionary new neutron-scattering spectrometer called MACS (for multi-angle crystal spectrometer) at the National Insti-

tute of Standards and Technology’s Center for Neutron Research in Gaithersburg, Md. This instrument features one of the world’s most intense monochromatic cold neutron beams and a multichannel detector system. Essential parts of this device were designed and built at Johns Hopkins by the Instrument Development Group in the Department of Physics and Astronomy. As chair of the Experimental Facilities Advisory Committee, Broholm also was closely involved with the development in Oak Ridge, Tenn., of what he describes as the world’s most intense pulsed neutron source. These and other developments in neutron scattering instrumentation are greatly expanding the capabilities and the reach of the neutron scattering in condensed matter physics, chemistry, biology and materials science. Broholm also directs the Johns Hopkins Institute for Quantum Matter. Funded by the Department of Energy, IQM combines material synthesis, theory and advanced spectroscopies to understand and control materials dominated by quantum effects. Broholm joined the Johns Hopkins faculty in 1990 after two years as a postdoctoral member of the technical staff at Bell Laboratories. He holds a master’s degree in physics and electrical engineering from the Technical University of Denmark and a doctorate in physics from Denmark’s University of Copenhagen. Broholm was awarded a Presidential Faculty Fellowship in 1994, has served on the Department of Energy’s Basic Energy Sciences Advisory Committee and is presently a member of the Condensed Matter and Materials Research Committee run by the National Research Council.

JHU faculty and staff star in NIH videos about careers in genomics By Michael Peña

Berman Institute of Bioethics

ideo interviews featuring faculty and staff from the Johns Hopkins Berman Institute of Bioethics and School of Medicine debuted last week on the National Human Genome Research Institute’s Web site. The independently produced videos are meant to inspire high school and college students to consider careers in genomics or genetics. The library of nearly 50 videos, online at www.genome.gov/genomicCareers, presents would-be scientists with the many diverse career paths they might pursue in government, the nonprofit sector and academia. For instance, bioethicist Carlton Haywood Jr., an assistant professor at the Berman Institute, describes his work on issues of communication and trust between doctors and patients with sickle cell disease. In the 11-minute video, viewers also discover that his passion is fueled by his own experiences with the condition. The institute’s director, Ruth Faden, discusses how advances in genomics and genetics raise important, complex questions about bioethics, such as how much influence ought to be exerted in the future over the kinds of babies that are brought into the world. A

thought leader in her field, Faden suggests how teenagers can turn even writing assignments in a high school history or life-science class into an opportunity to explore bioethical issues. In the Sickle Cell Center for Adults at Johns Hopkins, its director, Sophie Lanzkron, talks about her dedication to improving the quality of care that those with the genetic disease currently receive. Genetic counselor Amanda Bergner explains how she helps children and families understand an inherited condition, how it might affect their lives and what resources are available. Other videos feature J.J. Strouse, an assistant professor of hematology; Allan Sison, a medical fellow in the Division of Pediatric Hematology; Mandy David, a physician assistant at the Johns Hopkins Sickle Cell Infusion Center; and Rachel Han, a laboratory research assistant in the Pediatric Hematology Center. The National Human Genome Research Institute unveiled the videos at the annual meeting of the National Science Teachers Association in Philadelphia. Most include transcripts and link to related career profiles on the Genomic Careers Resource site, which also features interactive tools such as video quizzes and a career-tracker program. NHGRI is an agency of the NIH.

8 THE GAZETTE • March 22, 2010

March 22, 2010 • THE GAZETTE A R R A

R E S E A R C H

Researchers receive $1 mill to map ‘mobile DNA’ in humans By Audrey Huang

Johns Hopkins Medicine

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

equencing the human genome was just one step in understanding our biology; researchers still know very little about the function of most of our DNA. Now, a team of researchers at the Johns Hopkins School of Medicine has been awarded $1 million in stimulus funding to examine how certain mobile segments of DNA known as transposons contribute to human genetic diversity, by mapping transposon locations in more than 100 people over the next two years. “Transposons contribute to human genetic diversity in ways we are just beginning to understand,” said Jef Boeke, professor of molecular biology and genetics, and director of the High Throughput Biology Center at the Institute for Basic Biomedical Sciences at Johns Hopkins. “We hope this work will provide the basis for future research looking at how transposons affect health and disease.” In addition to genes that code for proteins, which make up only a small fraction of our genomes, our DNA also contains so-called “junk DNA,” regulatory elements that control gene function and sequences involved in maintaining chromosome structure. Some of these regions have been difficult to sequence and are only partially included in the current human genome draft. Transposons are in this category, existing in many copies and in different places in each individual. The teams of Boeke and Kathleen Burns have developed a new method for iden-

Kathleen Burns and Jef Boeke lead teams at the School of Medicine that are examining how transposons contribute to human genetic diversity.

tifying a group of these sequences, the L1(Ta) LINE (long interspersed element) transposons. Several hundred thousand LINE elements are found in the human genome, and their locations vary from one person to the next. LINE transposons can move and, depending on where in the genome they land, can change the activity of a nearby gene. These changes in gene function can

in part lead to differences between people. “We are delighted about this award,” said Burns, an assistant professor of pathology and oncology and a lead investigator on the grant. “It is a great assist in bridging the basic science of transposon biology—where Jef Boeke and his group have been major leaders—with clinical human genetics.” The investigation is among the 364 stimulus-funded research grants and supplements totaling almost $180 million that Johns Hopkins has garnered since Congress passed the American Recovery and Reinvestment Act of 2009 (informally known by the

acronym ARRA), bestowing the National Institutes of Health and the National Science Foundation with $12.4 billion in extra money to underwrite research grants by September 2010. The stimulus package—which provided $550 billion in new spending, including the above grants—is part of the federal government’s attempt to bring back a stumbling economy by distributing dollars for transportation projects, infrastructure building, the development of new energy sources and job creation, and financing research that will benefit humankind. Johns Hopkins scientists have submitted about 1,300 proposals for stimulus-funded investigations, ranging from strategies to help recovering addicts stay sober and the role that certain proteins play in the development of muscular dystrophy to mouse studies seeking to understand how men and women differ in their response to the influenza virus. As of March 15, 120 staff jobs have been created at Johns Hopkins directly from ARRA funding, not counting jobs saved when other grants ran out, and not counting faculty and grad student positions supported by the ARRA grants.

Related Web site High Throughput Biology Center at Johns Hopkins:

www.hopkinsmedicine.org/institute _basic_biomedical_sciences/research/ research_centers/high_throughput_ biology_hit

Inexpensive acne drug found to prevent HIV breakout By Maryalice Yakutchik

Johns Hopkins Medicine

ohns Hopkins scientists have found that a safe and inexpensive antibiotic in use since the 1970s for treating acne effectively targets infected immune cells in which HIV, the virus that causes AIDS, lies dormant and prevents them from reactivating and replicating. The drug, minocycline, likely will improve on the current treatment regimens of HIVinfected patients if used in combination with a standard drug cocktail known as HAART (Highly Active Antiretroviral Therapy), according to research published now online and appearing in print April 15 in The Journal of Infectious Diseases. “The powerful advantage to using minocycline is that the virus appears less able to develop drug resistance because minocycline targets cellular pathways not viral proteins,” said Janice Clements, the Mary Wallace Stanton Professor of Faculty Affairs, vice dean for faculty and professor of molecular and comparative pathobiology at the Johns Hopkins School of Medicine. “The big challenge clinicians deal with now in this country when treating HIV patients is keeping the virus locked in a dormant state,” Clements said. “While HAART is really effective in keeping down active replication, minocycline is another arm of defense against the virus.” Unlike the drugs used in HAART, which target the virus, minocycline homes in on and adjusts T cells, major immune system agents and targets of HIV infection. According to Clements, minocycline reduces the ability of T cells to activate and proliferate, steps that are crucial to HIV production and progression toward full-blown AIDS. If taken daily for life, HAART usually can protect people from becoming ill, but it’s not a cure. The HIV virus is kept at a low level but isn’t ever entirely purged; it stays quietly hidden in some immune cells. If a person

stops HAART or misses a dose, the virus can reactivate out of those immune cells and begin to spread. The idea for using minocycline as an adjunct to HAART resulted when the Johns Hopkins team learned of research by others on rheumatoid arthritis patients showing the anti-inflammatory effects of minocycline on T cells. The Johns Hopkins group connected

Related Web sites Janice Clements:

www.hopkinsmedicine.org/mcp/ faculty_webpages/clements.html

Retrovirus Laboratory at Johns Hopkins:

www.hopkinsmedicine.org/mcp/ Retrovirus

‘Journal of Infectious Diseases’:

The success with the animal model prompted the team to study in test tubes whether minocycline treatment affected latency in human T cells infected with HIV. Using cells from HIV-infected humans on HAART, the team isolated the “resting” immune cells and treated half of them with minocycline. Then they counted how many virus particles were reactivated, finding completely undetectable levels in the treated cells versus detectable levels in the untreated cells. “Minocycline reduces the capability of the virus to emerge from resting infected T cells,” Szeto said. “It prevents the virus from escaping in the one in a million cells in which it lays dormant in a person on HAART, and since it prevents virus activation, it should maintain the level of viral latency or even lower it. That’s the goal: sustaining a latent noninfectious state.” The team used molecular markers to discover that minocycline very selectively

interrupts certain specific signaling pathways critical for T cell activation. However, the antibiotic doesn’t completely obliterate T cells or diminish their ability to respond to other infections or diseases, which is crucial for individuals with HIV. “HIV requires T cell activation for efficient replication and reactivation of latent virus,” Clements said, “so our new understanding about minocyline’s effects on a T cell could help us to find even more drugs that target its signaling pathways.” The research was supported by grants from the National Institutes of Health. Authors of the paper, in addition to Clements and Szeto, are Angela K. Brice, Sheila A. Barber and Robert F. Siliciano, all of Johns Hopkins; and Hung-Chih Yang, of National Taiwan University Hospital. To hear Janice Clements talk about her team’s discovery, go to www.youtube.com/ watch?v=C_ImNAEpOHY.

www.journals.uchicago.edu/toc/ jid/current

the dots between that study and previous research of their own showing that minocycline treatment had multiple beneficial effects in monkeys infected with SIV, the primate version of HIV. In monkeys treated with minocycline, the virus load in the cerebrospinal fluid, the viral RNA in the brain and the severity of central nervous system disease were significantly decreased. The drug was also shown to affect T cell activation and proliferation. “Since minocycline reduced T cell activation, you might think it would have impaired the immune systems in the macaques, which are very similar to humans, but we didn’t see any deleterious effect,” said Gregory Szeto, a graduate student in the Department of Cellular and Molecular Medicine working in the Retrovirus Laboratory at Johns Hopkins. “This drug strikes a good balance and is ideal for HIV because it targets very specific aspects of immune activation.”

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10 THE GAZETTE • March 22, 2010 F O R

Cheers

Cheers is a monthly listing of honors and awards received by faculty, staff and students plus recent appointments and promotions. Contributions must be submitted in writing and be accompanied by a phone number. BAYVIEW MEDICAL CENTER Rachel Levine , assistant professor of gen-

eral internal medicine, has received the Clinician-Educator Award from the MidAtlantic Society for General Internal Medicine. The award recognizes physicians who have displayed innovation and excellence in teaching and in the delivery of clinical care. Levine’s work focuses on undergraduate and graduate medical education, including residency training requirements, the well-being and personal growth of residents, and medical-student advising. She also has written about part-time careers in academic medicine. BLOOMBERG SCHOOL OF PUBLIC HEALTH Kevin D. Frick has been promoted to

professor, with tenure, in the Department of Health Policy and Management. Diane Griffin , the Alfred and Jill Sommer Professor and Chair of the W. Harry Feinstone Department of Molecular Microbiology and Immunology, has been elected to the governing council of the National Academy of Sciences. Griffin was one of four academy members elected to the council. Her three-year term begins July 1. Sekhar P. Reddy has been promoted to professor in the Department of Environmental Health Sciences. JOHNS HOPKINS HEALTH SYSTEM Pamela Paulk , vice president of human

resources for The Johns Hopkins Hospital and Health System, has received the Adult Good Samaritan Award from the American Red Cross of Central Maryland. The award was given to Paulk in honor of her decision last year to donate a kidney to Robert Imes, a painter/mechanic in the hospital’s Facilities Department. On June 22, Paulk and Imes participated in the first 16-patient, multicenter kidney transplant operation, coordinated by Johns Hopkins, during which Paulk’s kidney went to a patient in St. Louis, while Imes received one from a donor in Oklahoma City.

KRIEGER SCHOOL OF ARTS AND SCIENCES J. Michael Boardman has been ap

pointed professor emeritus in the Department of Mathematics. Karen Yasinsky , a lecturer on visual arts, animation and photography in the Department of Film and Media Studies, is one of three $25,000 winners in the 2010 Baker Awards given to artists living and working in the Baltimore region. The awards, given by the William G. Baker Jr. Memorial Fund, were established in 2008 to honor local artists and encourage those from elsewhere to move to the city and five surrounding counties. The award recognizes Yasinsky’s achievements in film animation. Her co-winners were Peter Minkler, a musician with the Baltimore Symphony Orchestra, and Richard Cleaver, a sculptor.

PEABODY INSTITUTE Guitarist Ben Beirs , a Preparatory fac-

ulty member, traveled to Bangalore, India, this month to perform in the 13th East West Musical Encounter, a festival presented by the Bangalore School of Music. The program included a collaboration with Indian classical musicians on tabla and flute. He also performed and gave workshops at the Nathaniel School of Music. D a r i y a B u k h a r t s e v a , a freshman piano student from Ukraine studying with Yong Hi Moon , is the subject of a feature story, “From Poverty to Peabody,” in this month’s Baltimore magazine. Prior to her enrollment at Peabody, she studied in

T H E

Aspen, Colo., with former Peabody faculty artist Ann Schein . Pianist Adam Golka , a GPD candidate studying with Leon Fleisher , made his Carnegie Hall debut with the New York Youth Symphony on March 7. Golka performed Rachmaninoff’s Concerto No. 3, conducted by Ryan McAdams, the orchestra’s 27-year-old music director. Sophomore Gleb Kanasevich , clarinet, a student of Anthony McGill , was awarded first prize in the 2010 Yale Gordon Competition for instruments other than keyboard, bowed strings and early music instruments. He will play Mozart’s Clarinet Concerto in A Major with the Peabody Symphony Orchestra next season, as well as give a recital on the Homewood campus. Kevin Puts , Composition faculty member in the Conservatory, was the subject of an article in Symphony, the magazine of the League of American Orchestras. The article, titled “In the Moment,” appears in the March/April issue. Ronaldo Rolim , a student of Benjamin Pasternack , won the senior age category for piano in the Baltimore Music Club Competition. He will perform in a recital on April 11 at the Peabody Preparatory’s Towson campus. SAIS J o h n E . M c L a u g h l i n , distinguished practitioner in residence at the Philip Merrill Center for Strategic Studies, was tapped by Dennis C. Blair, director of National Intelligence, to head the Obama administration’s investigations of challenges facing the U.S. intelligence community. These include the November shootings at Fort Hood, Texas, and the Dec. 25 bombing attempt of a Detroit-bound airliner. McLaughlin spent most of his career at the CIA, serving as the agency’s acting director and deputy director. Michael Plummer , the ENI Professor of International Economics at the Bologna Center, in January became head of the Development Division in the Trade and Agriculture Directorate of the Organisation for Economic Co-operation and Development in Paris. He is leading a team of researchers focusing on trade and development issues, mostly for nonmember countries. Although officially on leave of absence from SAIS, Plummer will continue to teach his course on Asian economic development on a biweekly basis. SCHOOL OF EDUCATION Robert Slavin , a professor in the Center

for Research and Reform in Education, has been named a fellow of the American Educational Research Association. The honor was awarded to 67 scholars this year in recognition of their exceptional scientific or scholarly contributions to education research or significant contributions to the field through the development of research opportunities and settings. The fellows will be inducted on May 1 during AERA’s 91st Annual Meeting in Denver. SCHOOL OF MEDICINE William Baumgartner , vice dean for

clinical affairs, professor of cardiac surgery and director of the Cardiac Research Laboratory, has received the national Thoracic Surgery Residents Association’s 2010 Socrates Award for his outstanding commitment to resident education and mentorship. Recipients of the award are selected from nominations made by cardiothoracic surgery residents throughout North America, who recommend recognition for faculty members who have demonstrated remarkable interest in resident training inside or outside the operating room. Shelly Choo , a fourth-year student, is one of only 20 medical students nationwide to receive a 2010 Leadership Award from the American Medical Association. The award will provide her with special training to develop her skills as a future medical and community leader. Currently a Doris Duke Clinical Research Fellow, Choo recently served as president of the Asian Pacific American Medical Student Association.

R E C O R D A C A D E M I C

C E N T E R S

A N D

A F F I L I A T E S

JHU Press names director for Project Muse

he Johns Hopkins University Press has appointed Dean Smith director of Project MUSE, its flagship electronic scholarly journals publishing program. Smith will oversee an expansion to include more archival journal content on the MUSE platform and enhanced services to subscribers, content providers and end users. “We’re delighted to welcome a highly regarded publishing professional like Dean to the Press and Project MUSE,” said Kathleen Keane, director of JHU Press. “We expect his thorough understanding of the digital publishing environment and of the challenges faced by scholarly publishers to be great assets in guiding MUSE’s future strategic initiatives and in maintaining its strong competitive position as a premier provider of online content in the humanities and social sciences.” Smith comes to Johns Hopkins with extensive publishing leadership experience and expertise in digital publishing initiatives, product management, technical direction, global sales and marketing, and strategic development.

Barbara Detrick has been promoted to professor of pathology. B a r r y G o r d o n , professor of neurology and cognitive science, has been honored by Autism Speaks, the nation’s largest autism science and advocacy organization, which chose his 2009 paper, “Later Language Acquisition in Nonverbal Individuals with Autism,” as among the top 10 research achievements in the field last year. The paper presented case study evidence that changed the common belief that autistic children over the age of 5 would not be able to develop the ability to speak. Adil Haider , assistant professor of surgery and co-director of the Trauma Outcome Research Group, and Elizabeth Wick , assistant professor of surgery, have each received a faculty research fellowship from the American College of Surgeons. Haider has received the ninth annual C. James Carrico Faculty Research Fellowship for the Study of Trauma and Critical Care, while Wick has received the 19th annual Franklin Martin, MD, FACS., Faculty Research Fellowship for her research into inflammation and tumors of the colon. Amit Jain , a second-year student, has received a 2010 Paul and Daisy Soros Fellowship for New Americans. Focusing his research on implant-related fractures and spinal deformities in children, Jain also is the co-inventor of a novel threedimensional method for examining tumor behavior. K a y R e d f i e l d J a m i s o n has been appointed as first holder of the Dalio Family Professorship in Mood Disorders. Hendree E. Jones has been promoted to professor of psychiatry and behavioral sciences, with a secondary promotion in Gynecology and Obstetrics. Deok-Ho Kim , a doctoral candidate in Biomedical Engineering, is one of just 13 graduate students nationwide to receive a 2010 Harold M. Weintraub Graduate Student Award from the Basic Sciences Division of the Fred Hutchinson Cancer Research Center. Kim will participate in a scientific symposium on May 7 at the Hutchinson Center in Seattle. Daniel A. Laheru has been appointed as first holder of the Ian T. MacMillan Professorship in Clinical Pancreatic Cancer Research, effective April 22. Bruce Leff has been promoted to professor of medicine. Dolores Njoku , assistant professor of

As director of content for the American Society for Training and Development, Smith created a digital publishing strategy for the society’s periodical, book and research publications. At the American Chemical Society, he oversaw dynamic growth in worldwide electronic access to the society’s publications, designing innovative pricing models, emphasizing library customer relations and implementing effective internal management systems. He previously spearheaded electronic publishing efforts for a variety of medical publication products at Chapman & Hall, and led traditional journal publishing programs at C&H and Springer-Verlag. An accomplished writer and published poet, Smith holds a bachelor’s degree from the University of Virginia and an MFA in creative writing from Columbia University. Project MUSE offers electronic access to more than 400 peer-reviewed journal titles from more than 100 university press, society and independent scholarly publishers, and is used by researchers and students in more than 60 countries.

pediatric anesthesiology and critical care medicine, has won the William F. Rienhoff Jr. Scholar Award for 2011–2013. Named for a Johns Hopkins–trained pioneer in thyroid research and lung cancer surgery, the biennial award recognizes excellence in the perioperative sciences and provides approximately $35,000 to support the recipient’s work. Njoku’s current research focuses on drug-induced, immune-mediated liver injury. Gerald V. Raymond has been promoted to professor of neurology in the Kennedy Krieger Institute. Michael Repka has been appointed as first holder of the Robert and Maureen Feduniak Professorship in Ophthalmology, effective Oct. 21. Charles Rudin has been promoted to professor of oncology. L i l l i e S h o c k n e y , University Distinguished Service Associate Professor of Breast Cancer; associate professor of surgery and of gynecology and obstetrics; associate professor in the School of Nursing; and administrative director of the Johns Hopkins Avon Foundation Breast Center, has been inducted into the Maryland Women’s Hall of Fame. She also received the 2009 National Health Network Foundation’s Service Excellence Award for her treatment of breast cancer patients. Victor Urrutia , assistant professor of neurology, has been appointed director of the Johns Hopkins Stroke Center. A member of the faculty since 2005, Urrutia was the first physician in his native Panama to treat patients with IV thrombolytic therapy for acute stroke. In 2004, he founded the Instituto Cerebrovascular de Panama, a nonprofit devoted to educating the public and health care providers about prevention and acute treatment of stroke, as well as to conducting research on cerebrovascular disease. Levi Watkins , professor of surgery and associate dean for postdoctoral programs, has received an Award of Excellence from the Thurgood Marshall College Fund. Named for the late Baltimore-born U.S. Supreme Court justice, the New York City–based fund provides scholarships, programmatic support, leadership training, internships and career development programs to minority students to prepare them to become future leaders. Continued on next page

March 22, 2010 • THE GAZETTE

Milestones The following staff members recently retired or celebrated an anniversary with the university in March 2010. The information is compiled by the Office of Faculty, Staff and Retiree Programs, 443-997-6060.

ACADEMIC AND CULTURAL CENTERS

Retiree C a r t e r , William, Jr., 13 years of service, Bioethics Institute 30 years of service K a r g a a r d , Lyn, Center for Talented Youth L e i b t a g , Susan, Bioethics Institute 25 years of service B r o d y , Linda, Center for Talented Youth S m i t h , Kendall, Jhpiego 20 years of service B a r n e t t , Jacqueline, Center for Talented Youth 15 years of service R e e d y , Nora, Johns Hopkins University Press 10 years of service Rebecca, Center for Talented Youth R a w l i n s , Barbara, Jhpiego To p p e r , Suzanne, Johns Hopkins University Press

Barron,

5 years of service B e r i s f o r d , Brent, Operations and Maintenance, Montgomery County Campus C o y n e , Brendan, Johns Hopkins University Press W e e k s , Karen, Center for Talented Youth BLOOMBERG SCHOOL OF PUBLIC HEALTH

35 years of service Te l l j o h a n n , Harriett, Epidemiology 30 years of service Patricia, Human Resources

Lambdin,

20 years of service B a l l , Jacqueline, Custodial Services H a h n - E s p o s i t o , Patricia, International Health O d w i n - D a C o s t a , Shelly, Environmental Health Sciences 15 years of service D r a y t o n , Sabrina, International Health G a r v i n , Jon, Information Systems H o p s o n - B o o n e , Cheryl, Epidemiology

Cheers Continued from preceding page SCHOOL OF NURSING Helene Grady has been named associate

dean for finance and administration, effective March 15. Prior to joining the School of Nursing’s leadership team, Grady oversaw the day-to-day operations and $28 million operating budget of the City of Baltimore Finance Department and its six bureaus. Grady also held positions in the administration of Philadelphia Mayor Edward G. Rendell and with Amtrak. Prior to her government service in Philadelphia, she served as staff to President Bill Clinton’s Working Group on Welfare Reform, a special task force whose work resulted in the introduction of the president’s 1994 Work and Responsibility Act. A graduate of La

10 years of service B r i n k l e y , Latia, International Health G l a s s , Constance, Custodial Services S u s a n , Jolie, Environmental Health Sciences 5 years of service B a r n e s , Keri, Office of the Dean G r i f f i n , Corey, Office of the Dean H u m p h r e y , Debora, Environmental Health Sciences KRIEGER SCHOOL OF ARTS AND SCIENCES

15 years of service K e l l y , Margaret, Physics and Astronomy 10 years of service A m u s s e n , Brance, Mind/Brain Institute G i e r , Margaret, Physics and Astronomy J o n e s , S. Leo, Center for Social Organization of Schools 5 years of service Kip, Physics and Astronomy

Kuntz,

PEABODY

10 years of service S c h w e n d e m a n , Mary, Piano Maintenance SAIS 5 years of service B e k e l e , Meseret, Financial Aid SCHOOL OF EDUCATION

15 years of service S u t e r , Margaret, Finance and Administration SCHOOL OF MEDICINE

Retiree Bertoldi,

Surgery

Arleeta, 16 years of service,

Collevecchio,

Elizabeth, 22 years of service, Neurosurgery 30 years of service

C r o s s , Barbara, Psychiatry G r a n d y - J o n e s , Phonecia, Pediatrics H o l z m u e l l e r , Christine, Anesthesiology

and Critical Care Medicine L o n g o , Patti, Biophysics and Biophysical Chemistry 25 years of service G u g l i o t t a , Pauline, Pediatrics H o l t z c l a w , Walter, Jr., Molecular

Pharmacology

20 years of service A u s t i n , Rhonda, Clinical Operations B u s c h i n g , Sharon, Pediatrics H o p k i n s , Elise, Health Safety and

Environment J i n , Lin, Neurology K i n d b o m , Kori, Psychiatry, BPRU K o r d e k , Douglas, Radiology S h a f f e r , Barbara, Pathology Ta y l o r , Uvonne, Medicine

Salle University, she holds a master of public policy degree from the Kennedy School of Government at Harvard University. Deborah E. Jones , an assistant professor in Acute and Chronic Care, has been accepted to participate in the Nurse Faculty Mentored Leadership Development Program. The NFMLD was developed by Sigma Theta Tau International, the honor society for nurses, in partnership with the Elsevier Foundation to enhance the personal leadership development of new nurse faculty to promote faculty retention and cultivate high-performing, supportive work environments in academe. Sarah “Jodi” Shaefer , an assistant professor in Community Public Health, and Mar y Terhaar , an assistant professor in Health Systems and Outcomes, have been selected as scholars for the Health Information Technologies Scholars project for 2010. The project is sponsored by a five-year $1.5 million grant provided by the

W a g n e r , Roseann, Clinical Practice Association S t r o b a c k , Deborah, Neurobiology

15 years of service C a r r - B r a d y , Alberta, Clinical Practice Association F i s h e l , Robin, Pulmonary G o t t l i e b , Julie, Research Administration G r a u s t e i n , Gail, General Internal Medicine H a n s t , Rebecca, General Internal Medicine J a c k s o n , Gregory, Urology J u d g e , Katharine, Oncology K e e s l e r , Laurie, Otolaryngology L a s k e r , David, Otolaryngology O l s e n , John, Office of Clinical Investigation, Vice Dean P e r r y , Manly, Facilities T h o r n q u i s t , Mary, Psychiatry 10 years of service B r a s w e l l , Wilhelmena, Pathology C o p p a g e , Kim, Pediatrics D a v i s , Belinda, HEBCAC D i n a v a h i , Ramani, Hematology E v a n s - L e t o c h a , Phoebe, Office of Senior Vice President for Johns Hopkins Medicine F i c e k , Kimberly, Pathology F o s t e r , Shirley, Facilities H o l e h a n , Marjori, Ophthalmology K a n e , Charles, Facilities K i m b a l l , Judith, Chairman’s Office M e d l e y , Machele, Clinical Practice Association M i l l e s , Glenn, Ophthalmology P e n d e r g r a s s , Belinda, Dermatology R o s q u i s t , Karen, Pediatrics T h o r n t o n , Pamela, Ophthalmology W a l c o t t , Dawn, Cardiology W h e e l e r , Sandra, Facilities Z h u , Richard, Urology 5 years of service A l a o f i n , Oluwatope, Gynecology/ Obstetrics A y d l e t t , Alicia, Infectious Diseases B i s h o p , Janet, Radiology B r a m b l e , Rosemary, Infectious Diseases B r o w n , Mary, Neurology B r o w n - P l o w d e n , Irish, Infectious Diseases C h a m b e r s , Sandra, Ophthalmology G a r t l e y , Rosanna, Medicine G h e r m a n , Adrian, Institute of Genetic Medicine H o w a r d , Ivory, Pediatrics H u l l , Dawn, Research Animal Resources K e e n e , Jeanette, Fund for Johns Hopkins Medicine K i n n , Angela, Geriatric Medicine K o o n c e , Kimberly, Clinical Practice Association L e m a , Yukiko, Psychiatry L i z o t t e , Jacqueline, Emergency Medicine M a l s t r o m , Thomas, Fund for Johns Hopkins Medicine M a t t h e w s , Gail, Clinical Practice Association

Health Resources and Services Administration and is a cooperative effort with the University of Kansas School of Nursing, the schools of nursing at the University of Colorado Denver and Indiana University, and the National League for Nursing. SHERIDAN LIBRARIES/ JHU MUSEUMS Mark Cyzyk , scholarly communications

architect in the Library Digital Programs Group, has been appointed to the editorial board of Information Technology and Libraries, the flagship publication of the American Library Association’s Library and Information Technology Association. His two-year term begins July 1. WHITING SCHOOL OF ENGINEERING Joel Bader has been promoted to associ-

ate professor, with tenure, in the Department of Biomedical Engineering, effective July 1.

M e l e n d e z , Johan, Infectious Diseases M i c h a e l , Kurt, Pathology M o s s m a n , Melanie, Biomedical

Engineering O ’ M e a l l y , Robert, Biological Chemistry P e a r c e , Gladys, Pathology P i w o w a r - M a n n i n g , Estelle, Pathology S i n g h , Sukhminder, Pulmonary T h o m p s o n - B e r k y , Linda, Nephrology W o l f e , Randall, Biological Chemistry W o n g , Margaret, Pathology SCHOOL OF NURSING

10 years of service H a s k i n s , Kelly, Acute and Chronic Care SHERIDAN LIBRARIES/ JHU MUSEUMS

5 years of service S c z e r b a , Reid, Sheridan Libraries UNIVERSITY ADMINISTRATION

Retiree Wa l t o n ,

Geraldine, 19 years of service, Facilities Management 40 years of service Vernon, Facilities Management

Kahl,

25 years of service M c L e a n , Patricia, Office of the Vice President and General Counsel W h e a t l e y , Thomas, Facilities Management 20 years of service J a c k s o n , Edward, Information Technology S c e l s i , Lisa, Development and Alumni Relations 15 years of service Tammy, Development and Alumni Relations Wa l k e r ,

10 years of service A l e x a n d e r , David, Office of the Vice President for Human Resources C a v a l l a r o , Louis, Account Receivables, Shared Services C o r e y , Jay, Creative Services M c C o r m i c k , Michael, Human Resource Benefits Administration 5 years of service Christopher, Development and Alumni Relations E d w a r d s , Sandra, Facilities Management G i r t o n , Vanessa, Office of the Vice Provost for Research G o o d m a n , Kenneth, Jr., Facilities Management H a r p e r , Leonard, Homewood Campus Safety Security Services T h o m p s o n , Brandon, Information Technology Dax,

M i c h a e l B e v a n has been awarded tenure as associate professor in the Department of Chemical and Biomolecular Engineering, effective July 1. Konstantinos Konstantopoulos, professor and chair of Chemical and Biomolecular Engineering, has been named a fellow of the American Institute for Medical and Biological Engineering. The honor recognizes his “seminal bioengineering research contributions involving a mechanistic understanding of the fluid shear effects on cancer metastasis and discovery of selectin ligands.” Natalia Trayanova , professor of biomedical engineering and a researcher in the Institute for Computational Medicine, has been selected as a fellow of the American Heart Association. The most distinguished level of the society, fellow status recognizes members who have realized major professional achievement and leadership within the AHA.

12 THE GAZETTE â&#x20AC;¢ March 22, 2010

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March 22, 2010 • THE GAZETTE M A R C H

2 2

–

2 9

Calendar Barnes & Noble Johns Hopkins.

Continued from page 16

by E.R. Curtius,” a German and Romance Languages and Literatures lecture by Thomas Pavel, University of Chicago. 101A Dell House. HW MUSIC Tues., March 23, 7 p.m. Homewood Arts Programs present the Peiyang Chorus from Tianjin University, China. (See story, p. 12.) $10 general admission; free for all JHU students with ID. Shriver Hall Auditorium. HW

Victoria Chiang, viola, performs works by Brahms, Enesco, Bruch and Shostakovich. $15 general admission, $10 for senior citizens and $5 for students with ID. Friedberg Hall. Peabody

Wed., March 24, 8 p.m.

Hopkins Symphony Orchestra presents a performance by violinist Patrick Hu, and pianist Hyun-Sun Seo, winners of the 2010 Hopkins Symphony Concerto Competition. (See story, p. 14.) $8 general admission, $6 for senior citizens, JHU affiliates and non-JHU students; free for JHU students. Shriver Hall Auditorium. HW

Sun., March 28, 7 p.m.

READ I N G S / B OO K TAL K S

Thomas Greco and Karl Spence will discuss and sign copies of their book Dining on the B&O: Recipes and Highlights From a Bygone Age.

Wed., March 24, 1 p.m.

S E M I N AR S

“NPY and Stress-Induced Obesity,” a Biochemistry and Molecular Biology seminar with Zofia Zukowska, Georgetown University Medical Center. W1020 SPH. EB

Mon., March 22, noon.

Mon., March 22, 12:15 p.m.

“Chromatin-mediated Control of Non-Coding RNA Transcription and DNA Replication,” a Carnegie Institution Embryology seminar with Toshio Tsukiyama, Fred Hutchinson Cancer Research Center. Rose Auditorium, 3520 San Martin Drive. HW Mon., March 22, 1:30 p.m.

“Photoacoustic Tomography: Breaking Through the Optical Diffusion Limit,” a Biomedical Engineering seminar with Lihong V. Wang, Washington University in St. Louis. 709 Traylor. EB (Videoteleconferenced to 110 Clark. HW ) Mon.,

March

22,

p.m.

“Regulation of the Simian Immunodeficiency Virus Long Terminal Repeat by C/EBP2 and IFN2-mediated Innate Immune Responses, in vitro and in vivo,” an Institute of Genetic Medicine seminar with Shruthi Ravimohan, SoM. Darner Conference Room. EB “Structure of Some Toric Spaces,” a Topology seminar with Martin Bendersky, CUNY. Sponsored by Mathematics. 308 Krieger. HW

Mon., March 22, 3 p.m.

March 23, 11 a.m . “Micromanagers of Metastasis,” a Biochemistry and Molecular Biology seminar with Li Ma, Whitehead Institute for Biomedical Research. W1020 SPH. EB

Tues.,

Tues., March 23, noon. “Curious Research—Asking Structural Engineering Questions in Construction Management,” a Civil Engineering seminar with Gunnar Lucko, Catholic University of America. B17 CSEB. HW Tues., March 23, 3 p.m. The 2010 M. Gordon Wolman Seminar—“Microbial Interactions With Emerging Chemical Contaminants and Nanoparticles” with Shaily Mahendra, UCLA. Sponsored by Geography and Environmental Engineering. 234 Ames. HW Wed., March 24, noon. “Geology of the Moon and Mercury,” an Earth and Planetary Sciences seminar with David Blewett, APL. 304 Olin. HW

“Learning Regeneration Strategies From Nature,” a Molecular Pathology seminar with Cheng-Ming Chuong, University of Southern California. Darner Site Visit Room (off Turner Concourse). EB

Wed., March 24, noon.

Wed., March 24, 12:15 p.m. “In vivo Analysis of the Lipid Components of Primordial Germ Cell Migration,” a Carnegie Institution Embryology thesis defense seminar with Tim Mulligan. Rose Auditorium, 3520 San Martin Drive. HW Wed.,

March

24,

p.m.

“Okounkov Bodies and Kahler Manifolds,” a Complex Geometry seminar with Yanir Rubinstein, Stanford University. Sponsored by Mathematics. 304 Krieger. HW “Koszul Resolutions for Algebras of Power Operations,” a Topology seminar with Charles Rezk, UIUC. Sponsored by Mathematics. 304 Krieger.

Wed., March 24, 3 p.m.

Policy seminar with Mark Kleiman, UCLA. 526 Wyman Bldg. HW Fri., March 26, 1 p.m. “Anaplastology and Prosthetic Rehabilitation of Facial Defects,” a Molecular and Comparative Pathobiology seminar with Juan Garcia, SoM. 181 BRB. EB

The David Bodian Seminar—“How Actions Alter Sensory Processing: Active Sensation in the Vestibular System” with Kathleen Cullen, McGill University. Sponsored by the Krieger Mind/Brain Institute. 338 Krieger. HW

Mon., March 29, 4 p.m.

“Nanoindentation of Hydrated Tissues and Hydrogels,” a Materials Science and Engineering seminar with Michelle Oyen, Cambridge University. 110 Maryland. HW

Wed., March 24, 3 p.m.

Wed., March 24, 4 p.m. “Chemistry of Cancer Chemopreventive Dithiolethiones,” a Pharmacology and Molecular Sciences seminar with James Fishbein, UMBC. West Lecture Hall (ground floor), WBSB. EB Thurs., March 25, 10:45 a.m.

“Constructing Supramolecular Polymer Architectures and Networks for Medical and Energy Applications,” a Chemical and Biomolecular Engineering seminar with Honggang Cui, Northwestern University. 110 Maryland. HW “What I Learned About Political Change at the Ford Foundation,” a Political Science seminar with Michael Lipsky, Georgetown University and Demos Institute. 366 Mergenthaler. HW

Mon., March 29, 4 p.m. “tRNA Diversity Is Required for Uniformity,” a Biophysics seminar with Olke Uhlenbeck, Northwestern University. 107 Jenkins. HW

S P E C I AL E V E N T S

The 2010 Foreign Affairs Symposium presents historian Niall Ferguson, Harvard University. Glass Pavilion, Levering. HW

Wed., March 24, 8 p.m.

W OR K S HO P S

Thurs., March 25, noon.

“Plasticity in Hypothalamic Stress Circuitry,” a Neuroscience research seminar with Jaideep Bains, University of Calgary. West Lecture Hall (ground floor), WBSB. EB

Thurs., March 25, 1 p.m.

Thurs., March 25, 4 p.m. “Applying Game Theory, Tipping Models and Behavioral Economics to the Problems of Crime Control,” an Institute for Policy Studies Social

Tues., March 23, noon, and Wed., March 24, 4:30 p.m.

MSE Library Tour and Intro to Research, a chance to learn how to find everything in the MSE Library and an overview of getting started with research. Sponsored by Research Services. M-Level, Electronic Resource Center. HW Thurs.,

March

25,

p.m.

“Introduction to Google Applications—Now With Wave!” a Bits & Bytes workshop, designed for faculty and TAs. Sponsored by the Center for Educational Resources. To register, go to www .cer.jhu.edu. Garrett Room, MSE Library. HW

Safety checklist continues to keep hospital infections in check By Stephanie Desmon

Johns Hopkins Medicine

he state of Michigan, which used a five-step checklist developed at Johns Hopkins to virtually eliminate bloodstream infections in its hospitals’ intensive care units, has been able to keep the number of these common, costly and potentially lethal infections near zero, even three years after adopting the standardized procedures. A report on the work was published in the Feb. 20 issue of BMJ (British Medical Journal). Peter Pronovost, a professor of anesthesiology and critical care medicine at the Johns Hopkins School of Medicine and a patient safety expert, says that the widely heralded success in Michigan—the first state system to tackle in a wholesale fashion the infections in central-line catheters that are ubiquitous in intensive-care units—has significantly changed the way physicians think about these infections. “Prior to our work, we thought these were largely inevitable infections and that they were simply a cost of being in the hospital,” said Pronovost, the report’s leader and the developer of the checklist. “Now we know they are universally preventable. We’ve reset the benchmark.” Many quality improvement innovations, Pronovost says, are a flash in the pan— successful while they are being implemented and monitored, only to fall by the wayside

once no one is watching. Sustainability of the kind seen in Michigan requires a “complete culture change” that goes well beyond checklists and reminders to wash hands and use chlorhexidine antiseptic, he says. Culture change means a work environment in which “nurses question doctors who don’t wash their hands or use the checklist diligently,” Pronovost said. “It means clinicians no longer thinking central-line infections are inevitable. They now believe these infections are preventable, and they are creating a culture where they are,” he said. Pronovost says that his new paper is one of the first large studies to demonstrate that the results of a quality-improvement program can be sustained. The checklist contains five basic steps for doctors to follow when placing a central-line catheter: wash their hands; clean a patient’s skin with chlorhexidine; wear a mask, hat, gown and gloves and put sterile drapes over the patient; avoid placing a catheter in the groin, where infection rates are higher; and remove the catheter as soon as possible, even if there’s a chance it might be needed again at some point. Central lines are used regularly for patients in the ICU to administer medication or fluids, obtain blood tests and directly gauge cardiovascular measurements such as central venous blood pressure. Each year roughly 80,000 patients become infected and 30,000 to 60,000 of them die, at a cost of $3 billion nationally. Before heading to Michigan,

Pronovost tested the checklist at The Johns Hopkins Hospital, where catheter infections have also been virtually eliminated. The new study covered more than 100 ICUs in the Michigan hospital system, which was a large pilot site for Pronovost’s infection-prevention measures. Alongside the use of the cockpit-style checklist, the program included training physicians and nurses about infection control and using special, standardized central-line supply carts controlled for one-time use. The safety plan also required immediate “stop now” orders by any member of the health care team when a checklist was not followed to the letter and feedback to each member of the care team about the number and rates of catheter-related bloodstream infections at weekly and quarterly meetings. The Centers for Disease Control and Prevention estimates that between 10 percent and 20 percent of inpatients acquire some type of infection while hospitalized. Before the checklist project in Michigan, the median rate of central-line infections there was about three per 1,000 catheterhours, above the national average. After 18 months, most Michigan ICUs reported none of these bloodstream infections. The new research shows that after three years, the same was true—a “breathtaking” result, Pronovost says. Pronovost and his team from the Johns Hopkins Quality and Safety Research Group are taking the checklist system across the

globe, with rollouts in the United Kingdom, Spain, parts of Peru and even Pakistan. They are also bringing the program to all 50 states. Last summer Health and Human Services Secretary Kathleen Sebelius called for a 75 percent reduction in these catheter infections over the next three years. Pronovost and his colleagues are partnering with state health departments and hospital associations across the country to make sure there is buy-in from the many stakeholders involved in preventing these bloodstream infections. The key to success is not just following standardized checklist steps, he says. To change culture, what’s more important is that hospitals also search for errors on a continuing basis, know their infection rates and monitor them after implementing safety innovations. Doctors and nurses need to know that the measures they are taking are working to realize that the science behind the checklist is valid, he says. “The use of checklists is not the endgame; reduced infection rates are,” Pronovost said. “The public wants to know: Am I going to get infected? If hospitals had to make these rates public, these infections would end.” Other Johns Hopkins researchers involved in the study are Christine A. Goeschel, Elizabeth Colantuoni, Lisa H. Lubomski, Sean M. Berenholtz, David A. Thompson, David Sinopoli, Sara Cosgrove, J. Bryan Sexton, Jill A. Marsteller and Dale Needham. The study was funded by the Agency for Healthcare Research and Quality.

14 THE GAZETTE • March 22, 2010 B U L L E T I N

P O S T I N G S

Job Opportunities

Notices Vote for Favorite Films — JHU Summer

The Johns Hopkins University does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or other legally protected characteristic in any student program or activity administered by the university or with regard to admission or employment.

Homewood

Office of Human Resources: Suite W600, Wyman Bldg., 410-516-8048 JOB#

POSITION

42273 42552 42591 42704 41766 42088 42212 42281 42293 42294 42337 42498 42528

Research Administration Trainee Disability Services Administrator Financial Aid Administrator Accounting Supervisor Sr. Programmer Analyst Development Officer Research Data Analyst Academic Services Assistant Sr. Research Assistant Sr. Organizational Facilitator Website Designer Academic Program Manager Environmental Sampling Technician

Schools of Public H e a l t h a n d N u r s i n g Office of Human Resources: 2021 East Monument St., 410-955-3006 JOB#

POSITION

42663 41770 42722 42594 42453 41473 41388 42206 42758 42479 41398 42720 42560 42901 40927 43044

Sr. Administrative Coordinator Nurse Practitioner Technical Support Analyst Budget Specialist HR Administrator, Leave and Records Program Specialist Program Officer Sr. Financial/Contracts Analyst Research Study Office Assistant Sr. Research Nurse Research Data Analyst Financial Aid Coordinator Research Program Assistant Academic Services Specialist E-Learning Coordinator, PEPFAR Sr. Biostatistician

School of Medicine

Office of Human Resources: 98 N. Broadway, 3rd floor, 410-955-2990 JOB#

POSITION

38035 35677 30501 22150 38064 37442

Assistant Administrator Sr. Financial Analyst Nurse Midwife Physician Assistant Administrative Specialist Sr. Administrative Coordinator

42601 42622 42643 42700 42021 42103 42291 42604 42733 42755 42267 42472 42520 42590 42628 42640 42652 42657 42724

Research Technologist Academic Program Manager Alumni Relations Associate Instrument Designer Locksmith Sr. Energy Services Engineer Project Manager, LDP Administrative Manager Research Data Analyst Stationary Engineer Academic Adviser Academic Services Specialist Staff Psychologist Assistant Program Manager, CTY Student Career Counselor Curriculum Specialist Communications Coordinator Academic Services Assistant Programmer Analyst

42220 42011 42973 42959 42540 42392 42539 42512 42669 42884 42711 40770 42099 42697 38840 41877 42837 41652 38886 42347 41463 40769 39063 42682

Programmer Analyst Program Specialist Clinical Outcomes Coordinator Baltimore Community Program Officer Program Administrator Administrative Coordinator Data Assistant Sr. Research Assistant Data Assistant Contracts Associate Research Data Coordinator Software Engineer Administrative Coordinator Research Program Supervisor Communications Specialist Health Educator Financial Manager Development Coordinator Research Assistant Research Program Coordinator Research and Evaluation Officer Software Engineer Research Assistant Financial Analyst

37260 38008 36886 37890

Sr. Administrative Coordinator Sponsored Project Specialist Program Administrator Sr. Research Program Coordinator

This is a partial listing of jobs currently available. A complete list with descriptions can be found on the Web at jobs.jhu.edu.

and Intersession Programs is again sponsoring a series of free outdoor movies and entertainment on the Homewood campus. It’s scheduled for five Friday nights on the

Summertime at Roland Park Country School For girls and boys in kindergarten through 12th grade

June 14 – August 27 Red Hot Summer Day Camp 18” Doll Camp Driver’s Education Arts and Drama Camps

o ã

Junior Naturalist Camp Hot Summer Camp Circus Camp Babysitting Class

Make this summer a memorable one at RPCS! For information, please call 410-323-5500, ext. 3091 or visit us on-line at www.rpcs.org

Roland Park Country School • 5204 Roland Avenue • Baltimore, MD

Keyser Quadrangle, and the Johns Hopkins community is invited to help choose the films. Fourteen choices ranging from old favorites (Princess Bride, Beetle Juice) to audience-pleasing recent ones (Up, The Blind Side, Where the Wild Things Are) are posted online at http://jhu.edu/summer/films/index .html. Each person can vote for up to three.

Winners in 2010 HSO Concerto Competition to perform Sunday By Edie Stern

Hopkins Symphony Orchestra

iolinist Patrick Hu and pianist Hyun-Sun Seo have won the 2010 Hopkins Symphony Orchestra Concerto Competition. Their prize for the two Johns Hopkins undergraduates is a performance with the Hopkins Symphony Chamber Orchestra at 7 p.m. on Sunday, March 28, in Homewood’s Shriver Hall. Hu will play the first movement of Mozart’s Violin Concerto No. 5 in A Major, K. 219. Seo will play the first movement of Chopin’s Piano Concerto No. 2 in F Minor, Opus 21. Also on the program will be Dominick Argento’s Royal Invitation: Homage to the Queen of Tonga, Paul Hindemith’s Sonata for Solo Viola, Opus 25 No. 1, and Steve Reich’s New York Counterpoint. Vladimir Lande will conduct. The competition was created by 2008 alumnus Hernan del Aguila, who wanted to give Johns Hopkins students on the Homewood campus a chance “to further their musical studies, gain experience in auditioning for professional musicians and receive public recognition for their work.” The competition is open to undergraduate and graduate students who are not pursuing degrees in music. The winners were chosen from an original field of 10 contestants, based on an application and audition. The judges were HSO music director Jed Gaylin, HSO chamber conductor Lande and Peabody Conservatory Dean Mellasenah Morris. Hu, a sophomore majoring in international studies, was born and raised in Honolulu, where he graduated from the Punahou School. He began playing violin at age 6, studying with Honolulu Symphony violinist James Stanford and concertmaster Ignace Jang. He won the

Tuitions Continued from page 1

Kids Kaleidoscope

B O A R D

School of Nursing expects to provide a significant increase in financial aid dollars as well. Some of the university’s nontuition sources of revenue—particularly earnings on the endowment and Maryland’s Sellinger Program supporting independent colleges and universities—have been cut significantly during the recession. Because of a decline in state revenues, for instance, this fiscal year’s appropriated Sellinger aid was cut more than 25 percent after the year began. Other revenue sources, such as philanthropy and federal research support, remain uncertain for the foreseeable future. Despite the difficult times, Daniels said, the university remains committed to two critical priorities: maintaining academic excellence and providing financial aid to students whose talent and hard work have earned them a Johns Hopkins education but who cannot afford one. “We cannot and will not compromise on either the quality of the educational experience or on our commitment to open

Punahou Symphony Concerto Competition and received an honorable mention in the Honolulu Symphony’s Youth Concerto Competition. He has participated in master classes with, among others, the Takács Quartet, Richard Young of the Vermeer Quartet, Martin Beaver of the Tokyo String Quartet, Pamela Frank and Sally O’Reilly. Hu is now HSO principal second violinist and co-concertmaster of the Hopkins Symphony Chamber Orchestra. He studies with Qing Li, principal second violinist of the Baltimore Symphony. Seo, a junior majoring in biomedical engineering, grew up in Seoul, South Korea, and moved to the United States when she was 11. She began studying piano at age 6, first with Lora Verkhovsky and then with Soonja Kim. Seo has won first prizes in numerous competitions, including those hosted by the Washington State Music Teachers Association, Seattle Young Artists Music Festival, Performing Arts Festival of Eastside, Eastside Solo & Ensemble and Korean Music Association. In Seattle, she was adjudicated by Vladimir Viardo, Paul Roberts and Leonard Richter. She attended the International School in Bellevue, Wash., where she played piano in the Jazz Band; as her senior project, she conducted a semester-long study of Chopin’s Ballades and performed solo concerts of works by Chopin, Mozart, Prokofiev, Brahms and Debussy. She now studies at the Peabody Conservatory with Corey McVicar. HSO programs are supported by a grant from the Maryland State Arts Council, an agency funded by the state and the National Endowment for the Arts. Tickets for the March 28 concert are free for Johns Hopkins students and Maryland state employees; $6 for other students, seniors (age 60+) and Johns Hopkins staff, faculty and alumni; and $8 general admission. Tickets will be available at the door.

that experience to students no matter their economic background,” Daniels said. Vincent Amoroso, director of the Office of Student Financial Services at the university’s Homewood campus, said that, for many undergraduates, financial aid reduces the actual cost of attending Johns Hopkins to well below the “sticker price.” “This year, about 40 percent of Homewood undergraduates received need-based grants from university sources, averaging $28,266 per student,” Amoroso said. Room and board charges for the upcoming year for Krieger and Whiting students at the Homewood campus will increase 3.9 percent, from $6,882 to $7,150 for a typical residence hall room and from $5,158 to $5,360 for the “anytime dining” meal plan. Room charges for Peabody students will be $5,800 for a double room, up 7.4 percent from this year’s $5,400; the “anytime” meal plan will be $5,900, up 3.5 percent from this year’s $5,700. Tuition increases for next year in other Johns Hopkins degree programs vary widely, ranging from no increase to up to 10.1 percent, depending on the nature of the program and where it is offered. For a complete listing of 2010–2011 Johns Hopkins undergraduate and graduate tuition rates, go to http://tinyurl.com/JHUtuition. G

March 22, 2010 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT

Bayview, $700/mo + sec dep (2-3BR, 1st flr) and $600/mo + sec dep (1BR, 2nd flr). 443-243-1651. Bayview area, 2BR house w/fin’d bsmt, W/D, prkng pad, walk to work, no pets; sec dep and credit check req’d. Elaine, 410-633-4750. Belvedere Square Market, 2BR, 1.5BA apt, upstairs unit w/lg living rm, dining area, kitchen, powder rm, hdwd flrs, fp, balcony, quiet neighborhood, avail April. $875/mo + utils. 410-435-6417 or ankumar1120@yahoo .com. Canton, 2BR, 2BA waterfront TH, furn’d, CAC, W/D, dw, stainless steel appliances, granite counters, marble flrs, balcony, 2-car garage, home entertainment system, plasma TV. 443-955-2040. Charles Village, 1BR unit in immaculate prof’l bldg across from Homewood campus and BMA, no pets/no smoking, 1-yr lease minimum, application/tenant history/ income refs req’d. 410-366-5232.

M A R K E T P L A C E

Stirling St, gorgeous house in historic district, several spacious suites, each has own BA (w/ jacuzzi tub), each upper suite has patio w/ Baltimore skyline view, share main flr, lg back patio/driveway. $925/mo incl utils. 614-9379350 or chasing.me@gmail.com. Union Square, luxury studio apt suite, hdwd flrs, stainless steel appliances, marble tile BA, eat-in kitchen, dw, W/D, AC, conv to JHMI/JHU/downtown and 95; wkly/monthly lease incls utils. 410-753-2522 or info@ therichardsonhouse.net (for rates). West Towson, 4BR, 2BA colonial house 15 mins to JHU, CAC, renov’d kitchen, garage; option to buy. $1,950/mo. 410-812-6716 or argye.hillis@gmail.com. Wyman Park, immaculate 3BR TH, W/D, dw, security, cable, deck, trees, prkng, 1 blk to JHU. $1,650/mo + utils. fullcirc1@verizon .net or Craigslist #164680824. 1BR, 1BA apt, 2 blks to JHH, brand-new appliances, off-street prkng available. $1,245/ mo. 202-491-8960 or llockhart@indebleu .com.

Charles Village/Guilford, 1BR, 1BA apt w/spacious living rm, full kitchen, patio, private entry, across from JHMI shuttle stop; also commercially zoned. $975/mo. 443-858-9118.

Big 2BR, 2BA condo w/balcony, 10th flr, nr campus/shuttle, new bamboo flrs and new appliances, pool, sauna, gym, reserved garage prkng, excel view, start date negotiable; also avail for sale. $1,850/mo incl utils. janstrat@ verizon.net.

Cross Keys Village, 1BR condo, hdwd flrs, CAC/heat, free prkng, 24-hr security, swimming pool. $900/mo + utils (water incl’d). 646-284-2279 or tamrirev@yahoo.com.

Temporary housing, lg BR, full kitchen, front porch, prkng, month-to-month lease, credit check req’d. $850/mo incl heat, elec and sec dep ($100). adecker001@yahoo.com.

East Baltimore, 3BR, 1BA TH, partly furn’d, 2 mi to Johns Hopkins, refs required, no pets. $950/mo + utils + sec dep. Anita, 410675-5951 or amt2813@gmail.com. Guilford, charming, spacious 4BR, 2BA TH, W/D, dw, hdwd flrs, 2-car garage. $1,600/ mo + utils. baltimore.guilford@gmail.com. Hampden, 3BR, 2BA TH, dw, W/D, fenced yd, nr light rail. $1,100/mo + utils. 410378-2393. Little Italy, new 2BR, 2BA condo, hdwd flrs, W/D, garage, nr JHH. $1,600/mo. 301379-8605 or ada921@hotmail.com. Mt Washington, 5BR, 3.5BA house w/2-car garage. $2,200/mo + utils. 443-939-6027 or qzzhao@gmail.com. Owings Mills, 2BR, 2BA condo, W/D, walk-in closets, storage, prkng, pool/tennis court privileges, backs to woods, conv to metro, walk to grocery, sm pets negotiable ($250 nonrefundable deposit), 1-yr lease. $1,250/mo. 410-336-7952 or ljohnsto@ mail.roanoke.edu. Patterson Park, furn’d BR, rehabbed BA, hdwd flrs, new kitchen appliances, dw, W/D, avail 4/1. $700/mo + sec dep ($1,000) incl utils. 848-391-6758 or nrafaels@gmail.com. Pikesville, 3BR TH, 2 full BAs, 2 half-BAs, hdwd flrs, brand new appliances, back deck, $1,800/mo; also elegantly restored 1BR apts on St Paul St, $700-$900/mo. Alex, 410812-0098. Seton Hill area, 5BR, 3.5BA TH, total rehab, 4 levels, hdwd flrs, ceramic tile BAs, 4 fps, nr bus line and light rail, pets OK on case-by-case basis. $2,500/mo. Val, 443994-8938 or yankybrit@hotmail.com. Johns Hopkins / Hampden WYMAN COURT APTS. (BEECH AVE.) Effic from $570, 1 BD Apt. from $675, 2 BD from $775 HICKORY HEIGHTS APTS. (HICKORY AVE.) 2 BD units from $750 Shown by Appointment 410-764-7776

www.brooksmanagementcompany.com

Furn’d rm across street from JHU medical campus. happyhut4u@yahoo.com. Renov’d 3BR waterfront w/pier, wraparound deck, W/D, dw, conv to JHH/JHU, available mid-April. $1,650/mo + utils + sec dep. 410790-6597 or sohare@verizon.net.

HOUSES FOR SALE

Charles Village (Carrollton Condos), lg, renov’d 2BR, 2BA, CAC/heat, 24-hr front desk, prkng spot. $150,000. emmakcontact@ yahoo.com. Forest Hill, immaculate 2BR, 2BA condo in beautiful area, patio, walkout, nr shopping, move-in cond. 410-879-7254. Harborview (Baltimore County), 2BR, 1BA single-family house, on 1 flr, hdwd flrs throughout, lg priv yd, off-street prkng. $164,900. 443-604-2797 or lexisweetheart@ yahoo.com. Howard County, 4BR, 3.5BA house, take advantage of buyer’s credit and closing help. $540,000. 443-326-5928, goolaniran@aol .com or http://slideshow.mris.com/slideshow .cfm?ListingKey=90142792359. Patterson Park (2428 E Baltimore St), renov’d parkfront w/old charm, CAC, new kitchen and BAs, walk to JHH. $269,000 (reduced). 443-722-3161 or skj2428@yahoo.com. Patterson Park, completely renov’d TH, new kitchen, expos’d brick wall, redwood hdwd flrs, fin’d bsmt,new windows, move-in cond. $159,900. cwags57@msn.com. Roland Park, 2BR co-op apt overlooking Wyman Park, next to Homewood campus, easy walk to JHMI shuttle. $134,900. 443615-5190. Cozy 3BR Cape Cod in the city, approx 7 mi to Hopkins, new appliances, hot tub on gorgeous flagstone patio. $325,000/best offer. 305-898-3871 (for appt) or for pics, go to www.zillow.com and enter 725 Hollen Road, Baltimore, MD 21212.

ROOMMATES WANTED

Share all new refurbished TH at 924 N Broadway w/other medical students, 4BRs, 2 full BAs, CAC, W/D, dw, w/w crpt, 1-min walk to JHMI. gretrieval@aol.com.

wknds, Silver Spring area; college student OK, references req’d. 202-498-3209 (after 6pm). Looking for mature, experienced nanny to care for infant in my home, FT, begin Sept 10. 410-889-3354 or sbrinkley@mac.com.

F wanted to share 2BR, 2BA apt in Owings Mills. $600/mo + utils. 443-823-0207 or stefieyf@gmail.com.

Residence assistants wanted to supervise 100 high school students for one-week camp at Homewood campus, July 10-26. 410-735-4382.

F wanted for private rm, avail April 6, share lg house, kitchen, living rm, dining rm, porch, deck, hot tub, garden, high-speed Internet; respectful household. $400/mo + utils. 419-963-8741.

Going on sabbatical? PhD returning for MPH at JHSPH seeking sm house or condo to rent or house-sit at any time this summer. 401-941-5434.

CARS FOR SALE

’97 Toyota Camry LE, green, automatic, all power, new tires, in very good cond, 116K mi. $3,699/best offer. 410-337-5124 or nonu444@gmail.com.

Loving and trustworthy dog walker avail day and evening, overnight sitting w/complimentary house-sitting services, impeccable references. alwayshomepc@gmail.com. How about tennis in the sun or going on a fun run? Seeking practice partner and/or running buddy. Lagom335@hotmail.com. Help wanted for spring clean-up yard work. $12.50/hr. Jim, 443-904-4399, 410-3667191 or jwiLLi33@gmail.com.

ITEMS FOR SALE

Couch/futon, $80; flr lamp, $10; coffee table, $10; bookshelf, $10; desk, $40; dresser, $40. LftL123@yahoo.com. Ceramic water dispenser w/wooden stand, holds 5-gal water bottle, excel cond. $50. bstiver@comcast.net. York Force III Olympic weight bench w/bar, weights, in great cond, $175/best offer; desk shelf organizer, $25; walnut coffee table, $25/best offer. 410-377-7354.

Student seeks garage space nr 501 St Paul and N Calvert, N Charles, Centre St, W Madison or E Monument, short- or long-term. 415-793-7368 or yeelai88@yahoo.com. Affordable landscaper/horticulturist avail to maintain existing gardens, can also do planting, designing and masonry; affordable, free consultations. 410-683-7373 or grogan.family@hotmail.com.

Bally’s Total Fitness health club membership; willing to pay transfer fee. $450. 410817-6866.

Need a winning headshot photo for a job interview or audition? Edward S Davis photography and videography. 443-6959988, eddaviswrite@comcast.net or www .edwardsdavis.com.

Air Climber exerciser w/accessories, owner’s manual, workout DVD containing all workouts, literature pack, body cord. 443-4636861, wifemomdiva@cavtel.net or www .airclimbertrial.com (for pics).

Spring is right around the corner! Interior/ exterior painting, home/deck power washing, general maintenance; licensed, insured, free estimates, affordable. 410-335-1284 or randy6506vfw@yahoo.com.

Antique dresser/bureau w/key and lock, dark wood, in great cond, $250; awesome full-size retro sofabed, yellow crushed velvet, great cond, $300. 410-733-6231.

Piano lessons taught by experienced teacher and master’s student at Peabody. 425-8901327 (for free placement interview).

Bean abdominal exerciser w/pump (beanshaped and easier to use than the ball), new in unopened box and Sunny Roller fitness wheel, used several times. $15 for both. 410-243-5719.

SERVICES/ITEMS OFFERED OR WANTED

Licensed landscaper available for leaf and snow removal, trash hauling, lawn maintenance spring/summer; help also wanted, Taylor Landscaping LLC. 410-812-6090 or romilacapers@comcast.net. Piano lessons w/experienced teacher, Peabody doctorate, all levels/ages welcome. 410-662-7951.

Looking for volunteer English tutor/conversation partner for patient in JHH, pref student fluent in Spanish and English. shmee@ iupui.edu.

Tutor available: All subjects/levels; remedial, gifted and talented; also college counseling, speech and essay writing, editing, proofreading, database design and programming. 410-337-9877 or i1__@hotmail.com.

Summer nanny needed (June, July and August), for 1- and 4-yr-old, 3 days/wk. $10-$15/hr. Erin, 410-746-3921.

Need help with your JHU retirement plan investments portfolio? Free consultations. 410-435-5939 or treilly1@aol.com.

Private caretaker for children, certified nursing asst for elderly client, in the home, dependable, will provide wonderful care for your loved ones. Mrs Shantie, 443-418-8663.

Friday Night Swing Dance Club, open to public, no partners necessary. 410-583-7337 or www.fridaynightswing.com.

Seeking mature nanny/sitter for girls 2 and 4 yrs old, PT, after school wkdays, some

Cleaning service, we’ll shine up your house, reasonable rates, pet-friendly. 443-5283637.

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines: • One ad per person per week. A new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 410-343-3362.

16 THE GAZETTE • March 22, 2010 M A R C H

2 2

–

2 9

Calendar

F I L M / V I DEO Mon.,

March

22,

6:30

p.m.

Screening of the films Azerbaijan: The Last Kankan, Battle for the Xingu and American Outrage. A Q&A session will follow the films. Part of the D.C. Environmental Film Festival, sponsored by the SAIS Energy, Resources and Environment Program. The Environmental Film Festival continues through March 28. For more information, go to http://www.dcenvironmentalfilmfest.org. Kenney Auditorium, Nitze Building. SAIS Tournées Festival of Contemporary French CInema , a

History of Art lecture by Kimberly Cassibry, University of California, Irvine. 3 Shaffer. HW Wed., March 24, 5:15 p.m.

“Music, History and Invectives: Paradiso XV–XVII,” a German and Romance Languages and Literatures lecture by Giuseppe Mazzotta, Yale University. 101A Dell House. HW Distinguished Lecture in Art of the Ancient Americas (three

parts) by Richard Burger, Yale University. Sponsored by History of Art. •

two-week film festival beginning Wed., March 24. (See story, p. 5, for description of the films and a schedule.) HW I N FOR M AT I O N SESSIONS Tues.,

China’s Peiyang Chorus on U.S. college tour B y A m y L u n d ay

Homewood

hina’s renowned Peiyang Chorus of Tianjin University will perform at 7 p.m. on Tuesday, March 23, in Johns Hopkins’ Shriver Hall Auditorium as part of an East Coast tour at the invitation of seven U.S. universities to promote cultural exchange between academic institutions in China and the United States. Other campuses on the tour are George Washington University; Indiana University–Purdue University Indianapolis; Indiana University, Bloomington; University of Delaware; Youngstown State University; and University of Chicago. General admission tickets are $10 for the public and free to Johns Hopkins students with ID. Tickets can be purchased at http://peiyangjhu.eventbrite .com. Johns Hopkins students may register at this site, though they are not required to do so. Eric Beatty, director of Homewood Arts Programs, has been planning this concert for several months

C OLLO Q U I A Thurs.,

March

25,

p.m.

“ ‘Butcher-like and Hatefull’: Domestic Medicine and Resistance to Surgery in Early-Modern England,” a History of Science and Technology colloquium with Seth Lejacq, SoM. Seminar Room, 3rd floor, Welch Medical Library. EB Thurs., March 25, 3 p.m. “Kepler

and Habitability of Exoplanets,” a Physics and Astronomy colloquium with Dimitar Sasselov, Harvard University. Schafler Auditorium, Bloomberg Center. HW Thurs., March 25, 3:45 p.m.

“Accidentally True Constraints in Phonotactic Learning,” a Cognitive Science colloquium with Bruce Hayes, UCLA. 134A Krieger. HW Fri., March 26, 2 p.m. “2010 Cyber Threats and Trends,” an Applied Physics Laboratory colloquium with Richard Howard, Verisign iDefense. Parsons Auditorium. APL

with recent alumna Xiaonan Kou. “I am thrilled to be able to present such a prestigious university chorus from China here at Johns Hopkins,” Beatty said. “Ms. Kou and I know our audience will enjoy this truly international and collaborative concert.” Peiyang Chorus is the official choral society of Tianjin University, the first modern university in China, established in 1895. The group was formerly known as Peiyang Singing Group, and later as Tianjin University Chorus, and adopted its present name in 1985. It has been awarded seven gold medals in international choral competitions and honored by the International Federation for Choral Music as a world-class chorus. The group consists of undergraduate and postgraduate students from different fields of study. For the past two decades, Peiyang Chorus has offered performances in more than 20 countries and regions. It has performed nearly 1,000 Renaissance, baroque, classical, romantic, modern and contemporary choral compositions, many of which it introduced to Chinese audiences. It also performs numerous operettas, symphonic choral compositions and Chinese folk songs.

general admission, $7 for senior citizens and students with ID. Friedberg Hall. Peabody D I S C U S S I O N / TAL K S Tues., March 23, 4:30 p.m.

“Central Asia’s Oil and Gas Sector Since the 2008 Financial Crisis: The Rising Role of China,” a SAIS Reischauer Center for East Asian Studies discussion with Hirokazu Saito, Mitsubishi Corporation. 806 Rome Building. SAIS “Moving Beyond the ‘Losing Turkey’ Debate: Turkey’s Transatlantic Value in the Middle East,” a SAIS European Studies Program panel discussion with Natalie Tocci, Istituto Affari Internazionali, Italy; Kemal Kirisci, Bogazici University; and Joshua Walker, Princeton University. Co-sponsored by the Transatlantic Academy of the German Marshall Fund. Rome Building Auditorium. SAIS Tues., March 23, 5 p.m.

“Latin America Today,” a Program in Latin American Studies discussion with Franklin Knight, KSAS. Suite 100, Office of

Wed., March 24, noon.

DA N C E

The Peabody Spring Dance Showcase. $14 Sat., March 27, 7 p.m.

Multicultural Affairs, 3003 N. Charles St. HW

March

23,

6:30

LE C TURE S The Martin Lectures by Fabrice Planchon, Université Paris 13. Sponsored by Mathematics. HW

•

Mon., March 22, 4 p.m.

•

Wed., March 24, 4:30 p.m. “Nonlinear Waves on

“Nonlinear Waves on Domains: Part I.” 302 Krieger.

Domains: Part II.” 304 Krieger. The 2009–2010 Templeton Research Lectures by Mar-

tin Nowak, Harvard University (except where noted). Sponsored by the Evolution, Cognition and Culture Project. HW •

Wed., March 24, 12:30 p.m.

Mon., March 22, 4 p.m.

“The Evolution of Cooperation.” Mason Hall Auditorium.

“Addressing Corruption in Africa,” a SAIS African Studies Program discussion with Nuhu Ribadu, Center for Global Development. 500 BernsteinOffit Building. SAIS

•

Tues., March 23, 4 p.m.

Thurs., March 25, 4:30 p.m.

•

Wed., March 24, 4:30 p.m.

The Africana Studies Critical Thought Collective on the text Pedagogies of Crossing, Meditations on Feminism, Sexual Politics and the Sacred by Jacqui Alexander (the text is available at lorgiag@yahoo.com). Sponsored by the Center for Africana Studies. 113 Greenhouse. HW Thurs., March 25, 5:30 p.m.

“The Importance of Being Virtual,” a Friends of the Libraries’ panel discussion on social media. Mason Hall Auditorium. HW Fri., March 26, 12:30 p.m.

“Promoting Cooperation Between Local Governments and Civil Society Organizations,” a SAIS International Development Program discussion with Mirza Jahani, CEO, Aga Khan Foundation USA. Room 500, Bernstein-Offit Building. SAIS

•

“Evolutionary Dynamics.” Co-sponsored by Biomedical Engineering. 110 Clark. “Pre-Life.” Co-sponsored by Biology. 26 Mudd. Thurs., March 25, 4 p.m.

“Evolution and Structure,” by Corina Tarnita, Harvard University. Co-sponsored by Applied Mathematics and Statistics. 304 Whitehead. • Fri., March 26, 3 p.m. “God and Evolution.” Co-sponsored by Campus Ministries. Bunting-Meyerhoff Interfaith Center. Mon.,

March

22,

5:15

Looking Glass: An Alternative Vision of the Yale-Peru Dispute Over the Bingham Machu Picchu Collections.” 104 Maryland. HW •

Thurs., March 25, 7 p.m.

•

Sat., March 27, 1 p.m.

p.m.

Information session for the Master of Liberal Arts Program, a chance to learn about the program, submit an application and talk to associate program chair Melissa Hilbish. A reception follows. Sponsored by Advanced Academic Programs. RSVP online to http://mla.jhu.edu/rsvp/index .html?ContentID=2061. Mason Hall Auditorium. HW

p.m.

“Affect,” a German and Romance Languages and Literatures lecture by Carsten Strathausen, University of Missouri. 101A Dell House. HW Mon., March 22, 6 p.m. “From Province to Capital: Arch Monuments in the Roman Empire,” a

Thurs., March 25, 10:30 a.m. “The Other Side of the

“Monumental Architecture and Sociocultural Organization in the Coastal Civilization of Peru: The Case of the Manchay Culture.” Parlor, Walters Art Museum. “Discovering the Manchay Culture: Adventures in the Study of Early Peruvian Civilization.” Graham Auditorium, Walters Art Museum.

Thurs., March 25, 4:15 p.m.

The Tudor and Stuart Lecture— “The Zany Science” by Sianne Ngai, UCLA. Sponsored by English. 201C Dell House. HW Thurs., March 25, 5:15 p.m.

“Force of Law: Police Performance and Visual Arts in Latin America,” a German and Romance Languages and Literatures lecture by Fernando Rosenberg, Brandeis University. 101A Dell House. HW The Jan M. Minkowski Memorial Lecture in Quantum Electronics—“Nonlinear Optics on the Nanoscale: Toward Terabit Optical Processors” by Benjamin Eggleton, ARC Centre of Excellence for Ultrahigh-Bandwidth Devices for Optical Systems. Sponsored by Electrical and Computer Engineering. Mason Hall Auditorium.

Fri., March 26, 3 p.m.

Dean’s Lecture III—“Patient-Physician Relationships and Solving the Health Disparities Conundrum” by Lisa Cooper, SoM. Hurd Hall.

Mon., March 29, 4 p.m.

EB Mon., March 29, 5:15 p.m.

“Magic and Tragedy: Balzac Seen Continued on page 13

Calendar

Key

APL BRB CRB CSEB

(Events are free and open to the public except where indicated.)

Applied Physics Laboratory Broadway Research Building Cancer Research Building Computational Science and Engineering Building EB East Baltimore HW Homewood KSAS Krieger School of Arts and Sciences PCTB Preclinical Teaching Building SAIS School of Advanced International Studies SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering