The Gazette by The Johns Hopkins University

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Covering Homewood, East Baltimore, Peabody,

How did they do it? And how

Jack Griffin of BSI, left, and

SAIS, APL and other campuses throughout the

can you? Visit with 39 alumni

high-energy physicist Thomas

Baltimore-Washington area and abroad, since 1971.

authors to find out, page 10

Fulton have died, page 3

April 25, 2011

The newspaper of The Johns Hopkins University

A P P O I N T M E N T

Volume 40 No. 32

E V E N T

At journey’s end

Bates president named new head of CTY By Tracey A. Reeves

Homewood

Continued on page 4

COURTESY OF KAREN HONG

laine Tuttle Hansen, president of Bates College and an accomplished scholar, educator and leader, has been named executive director of The Johns Hopkins University’s Center for Talented Youth. Hansen will step Elaine Tuttle down from the presidency of the Maine college in July after Hansen will nine years and start her new position assume her Aug. 1. She will succeed Lea Ybarra, post at JHU who has led CTY for nearly 14 years, on Aug. 1 a tenure marked by incredible growth and the enhancement of the center as one of the most successful educational programs in the world for academically gifted primary- and secondary-school children. “I consider it a real privilege to be joining the outstanding Center for Talented Youth and the amazing research institution with which it is affiliated,” Hansen said. “The center itself is a place of such excellence with a mission consistent with what I have spent my whole life doing, and that’s how I knew that this next step was the right fit for me.” CTY is an arm of Johns Hopkins that finds exceptionally able primary- and secondary-school students and supports them with challenging advanced courses and other programs, both in person and online. In 2010, it enrolled more than 26,000 students in summer residential classes and year-round online courses, bringing to more than 444,000 the number of talented second- through 12thgraders it has served since 1979. Hansen’s appointment caps a national search by a universitywide committee for a highly accomplished leader who values academic excellence and embodies the ideals of the university and CTY, said Lloyd B. Minor, the university’s provost and senior vice president for academic affairs. In Hansen, the university has found a scholarly administrator who has

Karen Hong in Beijing’s famous Panjiayuan antique market with her host mother, Zhang Yan.

Woodrow Wilson fellows will share their findings at Friday event By Greg Rienzi

The Gazette

efore Karen Hong left for college, she and her parents didn’t discuss sex—at all. Hong, in fact, recalls the many awkward moments in the presence of her parents when television or movie characters just kissed on screen. Bedroom scenes? Off-limits. However, Hong’s interest in sexual health issues as a public health studies major at

Johns Hopkins would eventually lead her to broach the taboo subject with her mom, a native of the Fujian Province in China, who came to the United States in 1984. “I remember one time I asked my mom, How do you say sex in Chinese?” Continued on page 9

R E C O G N I T I O N

JHU deans and faculty named AAAS fellows By Lisa De Nike

Homewood

Johns Hopkins University dean, a vice dean and a professor are among the 212 fellows named to the 231st class of the American Academy of Arts and Sciences. Elected last week as new members were Katherine S. Newman, the James B. Knapp Dean of the Krieger School of Arts and Sciences and a professor of sociology; Chi

In Brief

Office of Johns Hopkins Physicians; Peabody orchestra concerts; Staff Recognition events

Van Dang, vice dean for research, the Johns Hopkins Family Professor in Oncology and a research professor of medicine, cell biology, oncology and pathology at the School of Medicine; and Gabrielle M. Spiegel, the Krieger-Eisenhower Professor of History in the Krieger School of Arts and Sciences. Some of the world’s most accomplished leaders from academia, business, public affairs, the humanities and the arts have been elected to the American Academy of Arts and Sciences, which was founded during the American Revolution by John

C a l e nd a r

BFSA Women’s Luncheon; JHU Nobel laureates; author Madison Smartt-Bell

Adams, James Bowdoin, John Hancock and others. Its dual role is to honor excellence in the arts and sciences and to provide independent, nonpartisan study of important societal issues. Newman, a widely published expert on poverty and the working poor, came to Johns Hopkins in September 2010 from Princeton University, where she had taught since 2004 and where she was the Malcolm Stevenson Forbes ’41 Professor in Continued on page 10

14 Job Opportunities 14 Notices 15 Classifieds

2 THE GAZETTE • April 25, 2011 I N B R I E F

MCC, Writer’s Center team up in programs for high schoolers

he Johns Hopkins Montgomery County Campus has forged a partnership with the Writer’s Center to offer five summer writing programs for high school students. The programs—which range in topics from fiction writing and playwriting to documentary filmmaking and writing a college essay—will be offered on the university’s Rockville campus, and the Writer’s Center in Bethesda will provide the instructors and curriculum. Classes range from one-day intensive seminars to twoweek workshops. For more information, go to web.jhu.edu/MCC/writing.html.

Dates announced for 2011 Staff Recognition milestone events

he Office of Work, Life and Engagement has announced the dates of the 2011 Staff Recognition events for those celebrating five, 10, 15, 20 and greater milestones in increments of five years of service with the university, and whose anniversaries fall between July 11, 2010, and July 10, 2011. The series of events starts with the Staff Recognition and Retirement Dinner at 6 p.m. on June 7 in Homewood’s Ralph S. O’Connor Recreation Center for staff celebrating anniversaries of 20 or more years in five-year increments, and for those retiring after more than 10 years on the job. Individual school receptions for staff marking five, 10 and 15 years of service are as follows: • SAIS, June 9, 3:30 p.m., 500 BernsteinOffit Building. • School of Nursing, June 14, noon to 2 p.m., Carpenter Room. • Homewood Recognition Reception (Academic and Cultural Centers, Carey Business School, Homewood Student Affairs, Jhpiego, Krieger School of Arts and Sciences, Peabody Institute, Professional Schools Administration, School of Education, Sheridan Libraries/JHU Museums, Johns Hopkins Club, JHU Press, University Administration and Whiting School of Engineering), June 15, 3 to 4:30 p.m., Glass Pavilion, Levering Hall. • Bloomberg School of Public Health, June 21, 3:30 to 5 p.m., Feinstone Hall. • School of Medicine, June 27, 3 to 4:30 p.m., Turner Concourse. For more information about the program and events, contact Amanda Sciukas at asciuka1@jhu.edu or 443-997-0345.

JHM establishes new Office of Johns Hopkins Physicians

o align the needs and direction of physicians in the Johns Hopkins Health System with those of faculty clinicians in the Johns Hopkins School of Medicine, Edward D. Miller, dean of the

Editor Lois Perschetz Writer Greg Rienzi Production Lynna Bright Copy Editor Ann Stiller Photography Homewood Photography A d v e rt i s i n g The Gazelle Group Business Dianne MacLeod C i r c u l at i o n Lynette Floyd Webmaster Lauren Custer

medical faculty and CEO of Johns Hopkins Medicine, announced last week the creation of the Office of Johns Hopkins Physicians, to be headed by a senior vice president and a deputy. William Baumgartner, he said, will serve as JHM senior vice president and Steven Kravet as deputy. Baumgartner is vice dean for clinical affairs and president of the School of Medicine Clinical Practice Association. Kravet is president of Johns Hopkins Community Physicians. Both will continue in those roles. Baumgartner and Kravet will coordinate the activities of the Clinical Practice Association, Johns Hopkins Community Physicians and all other physicians now part of or joining JHM, regardless of entity or location.

SAIS hosts D.C. launch of Francis Fukuyama’s new book

t 12:30 p.m. today, SAIS and The American Interest will host the Washington, D.C., book launch of The Origins of Political Order: From Prehuman Times to the French Revolution by Francis Fukuyama, a senior fellow at the SAIS Foreign Policy Institute and the Olivier Nomellini Senior Fellow at Stanford University. Following Fukuyama’s remarks, Adam Garfinkle, the editor of The American Interest, and Michael Woolcock, lead social development specialist for the World Bank’s Development Research Group, will provide commentary. Author of the bestselling The End of History and the Last Man, Fukuyama provides in his new book a sweeping account of how today’s basic political institutions developed. A webcast of the event will be available at www.sais-jhu.edu.

Last Peabody orchestra concerts of season set for this week

he two student orchestras of the Peabody Conservatory will give their last performances of the season at 8 p.m. on April 27 and 30 in Miriam A. Friedberg Concert Hall. Faculty members Edward Polochick and Leon Fleisher will conduct. On Wednesday, Polochick will conduct the Peabody Concert Orchestra in a performance of Robert Schumann’s Symphony No. 1 in B-flat major, Op. 38, Spring, and Mozart’s Requiem Mass in D minor, K. 626. Performing the Requiem with the orchestra will be the Peabody Singers and the Peabody-Hopkins Chorus. On Saturday, Fleisher will guest-conduct the Peabody Symphony Orchestra in a performance of William Walton’s Partita for Orchestra and Beethoven’s Symphony No. 3 in E-flat major, Op. 55, Eroica. Tickets are $15, $10 for seniors, $5 for students with ID. To purchase tickets, call the Peabody Box Office at 410-234-4800.

Contributing Writers Applied Physics Laboratory Michael Buckley, Paulette Campbell Bloomberg School of Public Health Tim Parsons, Natalie Wood-Wright Carey Business School Andrew Blumberg, Patrick Ercolano Homewood Lisa De Nike, Amy Lunday, Dennis O’Shea, Tracey A. Reeves, Phil Sneiderman Johns Hopkins Medicine Christen Brownlee, Stephanie Desmon, Neil A. Grauer, Audrey Huang, John Lazarou, David March, Vanessa McMains, Ekaterina Pesheva, Vanessa Wasta, Maryalice Yakutchik Peabody Institute Richard Selden SAIS Felisa Neuringer Klubes School of Education James Campbell, Theresa Norton School of Nursing Kelly Brooks-Staub University Libraries and Museums Brian Shields, Heather Egan Stalfort

The Gazette is published weekly September through May and biweekly June through August for the Johns Hopkins University community by the Office of Government, Community and Public Affairs, Suite 540, 901 S. Bond St., Baltimore, MD 21231, in cooperation with all university divisions. Subscriptions are $26 per year. Deadline for calendar items, notices and classifieds (free to JHU faculty, staff and students) is noon Monday, one week prior to publication date. Phone: 443-287-9900 Fax: 443-287-9920 General e-mail: gazette@jhu.edu Classifieds e-mail: gazads@jhu.edu On the Web: gazette.jhu.edu Paid advertising, which does not represent any endorsement by the university, is handled by the Gazelle Group at 410343-3362 or gazellegrp@comcast.net.

April 25, 2011 • THE GAZETTE

O B I T U A R Y

John W. Griffin, nerve disorder expert and researcher, dies B y C h r i s t e n B r o wn

lee

Johns Hopkins Medicine

ohn W. “Jack” Griffin, an internationally acclaimed and admired expert on diseases of the peripheral nervous system, founding director of the Johns Hopkins Brain Science Institute and former director of the Johns Hopkins School of Medicine’s Department of Neurology, died April 16 after a long battle with bladder cancer. He was 69. Griffin was one of the world’s top experts, both as a clinician and researcher, on peripheral nerve disorders. He became a leading figure in studies of Guillain-Barre syndrome, a disease in which the immune system attacks nerves, leading to rapidly evolving paralysis of the legs, arms, face and muscles used in breathing. He went on to play a central role in studying the mechanisms of nerve degeneration and regeneration, and his work led to numerous treatments for neuromuscular disorders. So highly regarded was Griffin and so extensive was his influence in the study of axons, the nerve fibers that conduct electrical impulses, and the Schwann cell, which covers and protects axons, that a two-day symposium titled The Friends of the Axon, the Schwann Cell and Jack Griffin was held at Johns Hopkins in January. It featured an international gallery of top scientists in these fields, who heard more than a dozen scientific talks and shared snippets

Jack Griffin

of a life that undeniably altered the practice of neurology. Among those who spoke glowingly of Griffin while describing their own latest research were faculty from the universities of Dusseldorf, Heidelberg and Glasgow, as well as from Harvard, Emory and New York universities; the universities of Pennsylvania, Massachusetts, Michigan and California, San Diego; Hunter College; the Cleveland Clinic; and Johns Hopkins. “Jack had a hand in developing about 15

O B I T U A R Y

Thomas Fulton, 83, father of high-energy physics at JHU By Lisa De Nike

Homewood

homas Fulton, considered the father of high-energy physics at The Johns Hopkins University, died on April 8 of heart failure at the age of 83. Born Tomas Feuerzeug in Budapest, Hungary, in 1937, Fulton immigrated with his family to the United States when he was 14 years old in order to escape the Nazi regime. The family first fled to Spain and then on to Cuba before taking a boat to their final destination: New York City. There, young Fulton enrolled at Stuyvesant High School, from which he graduated in 1946 with honors in physics and English. He earned his bachelor’s, master’s and doctoral degrees at Harvard, where he studied with Nobel Prize winner Julian Schwinger, known as one of the greatest physicists of the 20th century. An expert in quantum electrodynamics, Schwinger was Fulton’s thesis adviser. Fulton then did two years of postdoctoral work at the Institute for Advanced Study in Princeton, N.J., where he worked under J. Robert Oppenheimer, scientific director of the Manhattan Project. It was in Princeton that Fulton had a onehour private meeting with Albert Einstein, who died only four months later. Fulton had requested the get-together and was pleasantly surprised—and thrilled—when the physics legend agreed. In Fulton’s unpub-

lished memoir, he describes Einstein’s lavish halo of white hair and his office blackboard, which was covered with equations seeking to construct a unified theory of gravitation and electromagnetism. Fulton joined the faculty at Johns Hopkins as an assistant professor of physics in 1956 and remained here until his retirement in 2000. He brought with him expertise in the areas of high-energy physics—the study of which had not yet emerged at Johns Hopkins—quantum electrodynamics and atomic theory. He was named an associate professor in 1959 and attained full professorship in 1964. During his time on the Homewood campus, Fulton not only helped found the particle theory physics group that first tackled high-energy physics research, but he also mentored numerous graduate students who are now on the faculty of leading universities. He was a fellow of the American Physical Society and was awarded a John Simon Guggenheim Fellowship and a Fulbright Research Scholarship. In addition to his love of physics and science, Fulton was passionate about opera, classical music, art, traveling, rock climbing, photography, biking and skiing. Friends and family members describe him as a true Renaissance man. His wife, Babbette, a retired teacher, died in 2006. He is survived by his two daughters, Judy Fulton and Ruth Kiselewich; two sonsin-law; and four grandchildren.

different treatments and diagnostic tests— most men would be happy with any one of these achievements,” said Justin McArthur, professor of neurology, pathology and epidemiology in the Johns Hopkins School of Medicine and neurologist in chief of The Johns Hopkins Hospital. “He was a superb neurological detective. The name of Jack Griffin’s farm baseball team was the Optimists. It echoes Jack’s essential nature, that of an empathic clinician as well as a superb neurologist. With his patients, it was always, ‘You will recover.’ With his research, it was, ‘This is going to work.’ There was a tremendous positive spirit felt throughout his career.” “Jack was the model clinician scientist,” said Jeffrey Rothstein, who is now the John W. Griffin Director of the Johns Hopkins Brain Science Institute, as well as a professor of neurology and neuroscience at the Johns Hopkins University School of Medicine and director of the Robert Packard Center for ALS Research at Johns Hopkins. “His commitment to translating clinical observations to the lab to understand how nerve diseases occur was unsurpassed, and based on the essence of his personality and attributes here at Hopkins, an open, friendly, engaging collaboration.” Beginning as a Neurology resident in 1970, Griffin spent his entire four-decade career in the Johns Hopkins School of Medicine, except for a 1973–1975 stint as a clinical associate at the National Institute of Neurological and Communicative Disorders and Stroke in Bethesda, Md. He ultimately earned professorships in Neurology, Neuroscience and Pathology. Griffin was named head of the School of Medicine’s Department of Neurology and neurologist in chief of The Johns Hopkins Hospital in 1999. As head of Neurology, he oversaw the expansion of what already was the country’s largest neurology critical care unit, to a 22-bed facility for the treatment of patients with severe strokes or traumatic brain injuries, intractable seizures and gunshot wounds, or those requiring recuperation from significant brain or back surgeries. By 2002, he could tell a writer for Johns Hopkins Medicine’s publication Dome that the hospital now had no peer in neurocritical care. “There is no other comparable department” for neurological treatment in the country, he said. “The science of neurocritical care has grown up, and it makes an enormous difference in outcomes. Lives are saved, and hospital stays are shortened. This new unit provides a setting where the most advanced treatments can be brought to bear.” Griffin also was a much-admired teacher, earning the School of Medicine’s Professors Award for Excellence in Teaching. He also served as president of the Peripheral Nerve Society, the Society for Experimental Neu-

ropathology and the American Neurological Association. In 2004, he and his wife, Diane Griffin, an eminent virologist and professor of both medicine and neurology and the Alfred and Jill Sommer Professor and Chair of the W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health, became the first husband-and-wife team in the history of Johns Hopkins Medicine to be elected to the prestigious Institute of Medicine in the same year. Griffin remained head of Neurology until 2006, when ill health compelled him to step down from the post. He recovered, however, and in 2007 became the founding director of the Brain Science Institute. That same year he received the Johns Hopkins Heritage Award for outstanding service to the university. “Hopkins, and the greater scientific world, has lost a great leader,” said Edward Miller, the Frances Watt Baker, M.D., and Lenox D. Baker Jr., M.D., Dean of the Medical Faculty and the chief executive officer of Johns Hopkins Medicine. “His professional and personal commitment to his patients and research were unparalleled. Our condolences go out to his family, both at home and at Hopkins; his former patients; and the research community. He’ll be greatly missed.” A native of Nebraska, Griffin was a 1963 Phi Beta Kappa graduate of Grinnell College in Iowa. He obtained his medical degree in 1968 from Stanford, where he spent two years as an intern and resident before coming to Johns Hopkins. A prolific researcher, he focused on understanding the mechanisms of degeneration and regeneration in peripheral nerves, including the roles of growth factors and molecules within the Schwann cell. He published more than 300 studies in scientific journals, edited major textbooks on peripheral neuropathies and was editor of the journal Nature Neurology. As a mentor, he trained more than two dozen postdoctoral fellows, all of whom have gone on to distinguished careers at universities and institutes reaching from Australia, China and Taiwan to Europe and the Middle East and throughout the United States. Griffin stepped down from his position as director of the Brain Science Institute just this month. The directorship will continue in his name. Rothstein was named as the first John W. Griffin Director of the Brain Science Institute. In addition to his wife, Griffin is survived by sons Todd and Erik, daughtersin-law Esther and Tara, and granddaughter Sophie. A memorial service was held April 20 at St. Mark’s Lutheran Church in Baltimore.

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spent much of her career developing and nurturing academic talent in young people, he said. “Elaine Hansen is a proven academic leader with a long-standing commitment to undergraduate education,” Minor said. “She brings a wealth of experience and an invaluable perspective to CTY and to the university. I have been deeply impressed by Elaine and her vision for CTY, and I am thrilled that she will be joining Johns Hopkins.” President Ronald J. Daniels said that Hansen’s experience as a college president, provost, professor, fundraiser and fiscal, facilities and student life manager positions her to take on the opportunities and challenges that face CTY. “Dr. Hansen is a seasoned, mature, experienced leader of a complex organization with myriad stakeholders,” Daniels said. “We see her bringing all of that and her academic credentials to CTY and engaging the community in the kind of strategic planning that has made her so successful at Bates and throughout her career.” Hansen, an authority on Middle English literature, contemporary women’s writing and feminist theory, is credited at Bates with increasing student diversity, expanding and improving campus facilities and grounds, and leading the college’s largest-ever fundraising campaign. In a message announcing Hansen’s departure to the Bates community, Michael Bonney, chair of the college’s board of trustees, described Hansen as an inspirational leader whose contributions to the college will be felt by generations of future Bates students, faculty, staff and alumni. “Elaine has managed the college with skill and determination through the most turbulent economic times in recent memory,” Bonney said. “My fellow trustees and I are deeply grateful for her adroit leadership, which ensures that the college has the

Elaine Tuttle Hansen

financial resources to support its strong and exciting future.” In her new role, Minor said, Hansen will be charged with leading CTY to new levels of local, national and global impact as the program seeks to expand learning opportunities for academically talented students in primary and secondary grades throughout the country and internationally. She will report to the provost, directing a staff of 180 fulltime employees, 220 part-time employees and 1,600 summer programs employees, and managing a budget of more than $50 million. Minor said that Hansen also will work closely with David Andrews, dean of the School of Education, to build a collaborative research program focused on talented youth. “I have been inspired by my conversations with Dr. Hansen,” Andrews said. “Her vision for collaboration in strengthening research and building strong programs for talented and gifted students aligns perfectly with our aspirations in the School of Education, and I am excited about the important work we will do together.” Vice Provost Pamela Cranston, who led the search committee, said that Hansen will inherit a program that is fundamentally strong and uniquely poised to be a leader in today’s debate on gifted education.

“Given the changes in leadership and technologies, we believe that Dr. Hansen is in the best position to elevate CTY’s role in the discussion of gifted and STEM education,” said Cranston, referring to the disciplines of science, technology, engineering and mathematics. Ybarra announced in October that she would leave CTY after her successor was appointed and took office. Among her major accomplishments have been strengthening CTY’s budget, diversifying its student body and staff, and raising the program’s national and international footprint. “Under Lea’s leadership, CTY has played an important role in identifying and developing the academic talent of young students across the country and around the world,” Minor said. “What CTY does is inspiring, and what Lea has achieved is remarkable. We are deeply grateful for her vision, passion and service to Johns Hopkins.” Hansen is the seventh president of Bates since its founding in 1855. She earned her bachelor’s degree at Mount Holyoke College, her master’s degree at the University of Minnesota and her doctorate at the University of Washington. Before going to Bates, Hansen served as provost and professor of English at Haverford College. She also has been associate editor of the Middle English Dictionary at the University of Michigan and taught at Hamilton College. Hansen has received research grants from the National Endowment for the Humanities and the American Council of Learned Societies, and earned support from the Whitehead and Mellon faculty development funds. She has published numerous literary critical articles and reviews, and three books: Reading Wisdom in Old English Poetry (University of Toronto Press, 1988), Chaucer and the Fictions of Gender (University of California Press, 1992) and Mother Without Child: Contemporary Fiction and the Crisis of Motherhood (University of California Press, 1997). Hansen, the mother of two adult daughters, said that she and her husband look forward to moving back to the mid-Atlantic region, where they previously lived for 22 years. G

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April 25, 2011 • THE GAZETTE

By Maryalice Yakutchik

Johns Hopkins Medicine

esearchers at Johns Hopkins have discovered in mice a molecular wrecking ball that powers the demolition phase of a cycle that occurs at synapses—those specialized connections between nerve cells in the brain—and whose activity appears critical for both limiting and enhancing learning and memory. The newly revealed protein, which the researchers named thorase after Thor, the Norse god of thunder, belongs to a large family of enzymes that energize not only neurological construction jobs but also deconstruction projects. The discovery is described in the April 15 issue of Cell. “Thorase is vital for keeping in balance the molecular construction-deconstruction cycle we believe is required for memory formation,” said Valina Dawson, professor of neurology and neuroscience in the Johns Hopkins Institute for Cell Engineering. “It’s a highly druggable target, which, depending on whether you enhance or inactivate it, may potentially result in new treatments for autism, PTSD [post-traumatic stress disorder] and memory dysfunction.” The enzyme is one of many AAA+ ATPases that drive the assembly of proteins needed to form specialized receptors at the surfaces of synapses. These receptors are stimulated by neighboring neurons, setting up the signaling and answering connections vital to brain function. The Johns Hopkins team showed how thorase regulates the all-important complementary process of receptor disassembly at synapses, which ultimately tamps down signaling. Prolonged excitation or inhibition of these receptors—due to injury, disease, genetic malfunction or drugs—has been implicated in a wide array of learning and memory disorders. “Change in the strength of the connections between two nerve cells forms the basis of our ability to learn and remember,” Dawson said. This phenomenon, called synaptic plasticity, depends upon a balanced alternation of excitation and inhibition of receptors, she added. Using a powerful microscope to look at labeled neurons from the brains of mice, the scientists saw that thorase was concentrated in the synaptic regions of cells, leading them to focus studies on the protein interactions that happen there. First, they cut a protein aptly called GRIP1—it acts as scaffolding to hold GluR2 receptors to the surface—into various chunks and combined it with thorase. Encouraged by the fact that thorase and the GRIP1 scaffold did indeed bind tightly, they teased out the physiology of that interaction in the presence of lots of thorase and then no thorase. They discovered that the more thorase,

the quicker the scaffolding deconstructed and the faster the surface receptors decreased. Thorase causes GluR2 receptors and GRIP1 to release their hold on each other—and therefore the receptor’s grip at the surface of the synapse—they concluded. To see if the deconstruction of the protein complex had any effect on nervesignaling processes, they again used cells to record receptor activity by measuring electric currents as they fluxed through cells with and without thorase. In the presence of extra thorase, surface receptor expression was decreased, resulting in reduced signaling. Next, the team measured the rates of receptor recycling by tagging the protein complex with a fluorescent marker. It could then be tracked as it was subsequently reinserted back into the surface membrane of a cell. In cells in which thorase was knocked out, there was very little deconstruction/ turnover compared to normal cells. The scientists reversed the process by adding back thorase. Finally, the team conducted a series of memory tasks in order to compare the behaviors of normal mice with those genetically modified to lack thorase. When the animals lacking thorase were put into a simple maze, their behaviors revealed they had severe deficits in learning and memory. “Mice lacking thorase appear to stay in a constant state of stimulation, which prevents memory formation,” Dawson said. “Their receptors get up to the membrane where they are stimulated, but they aren’t being recycled if thorase isn’t present. If thorase doesn’t stop the excitation by recycling the receptor, it continues on and has deleterious effects.” Support for this research came from the National Institute on Aging and its Intramural Research Program, McKnight Endowment for Neuroscience, American Heart Association and Simon’s Foundation Autism Research Initiative. Authors of the paper, in addition to Valina Dawson, are Jianmin Zhang, Yue Wang, Zhikai Chi, Matthew J. Keuss, YingMin Emily Pai, Ho Chul Kang, Jooho Shin, Artem Bugayenko, Hong Wang, Yulan Xiong, Mikhail V. Pletnikov, Mark P. Mattson and Ted M. Dawson, all of Johns Hopkins.

Related websites Valina Dawson lab:

neuroscience.jhu.edu/ ValinaDawson.php

‘Cell’:

www.cell.com/current

J. PAUL GETTY TRUST

Discovered: ‘Thunder’ protein that regulates memory formation

Since 2008, Greg Britton has led the publishing program of the J. Paul Getty Trust, the largest museum publishing program in North America.

Gregory M. Britton appointed editorial director at JHU Press By Jack Holmes

Johns Hopkins University Press

regory M. Britton, who has led the publishing program at the Getty Museum and related institutions since 2008, has been appointed editorial director at the Johns Hopkins University Press. When he joins the staff on May 16, Britton becomes a senior member of the Press’ executive committee and assumes leadership of the Books Division’s editorial department of 10 full-time editors and assistants responsible for acquiring and publishing approximately 200 new titles annually. He replaces Trevor Lipscombe, who had served as the Press’ editor in chief and was appointed director of the Catholic University of America Press in fall 2010. “Greg Britton has a terrific track record as an editor and publisher, and he will bring vision and energy to his new role as our editorial director,” said JHU Press Director Kathleen Keane. “Greg has demonstrated a strong commitment to the publishing community through admirable service and leadership in the AAUP [Association of American University Presses] and the AAP [Association of American Publishers]. He shares our staff’s enthusiasm for the traditional values and aesthetics of print publishing, and his expertise will help us navigate the exciting digital future of books. We are very pleased to welcome Greg and his family to the JHU Press and to Baltimore.” Prior to his appointment at Johns Hopkins, Britton directed the Getty Publications

program of the J. Paul Getty Trust, the largest museum publishing program in North America, which includes the publications of the J. Paul Getty Museum, the Getty Research Institute and the Getty Conservation Institute. During his tenure, he expanded Getty’s publishing partnerships with European museums, launched the Getty Research Journal and created an ambitious digital initiatives plan. Before that, he was director of the Minnesota Historical SociBooks Division ety Press, where he oversaw a significant acquires and expansion of the publishing program and a publishes resulting increase in sales and visibility. about 200 Britton is a graduate of Wabash College in titles a year Crawfordsville, Ind., and was working on a doctorate in American history at the University of Wisconsin, Madison, when he began his career in publishing. “This is a challenging time in publishing, and I admire the tremendous innovation I see at JHU Press,” Britton said. “I am eager to join the Hopkins staff and look forward to helping shape their role in the future of scholarly communications.” Established in 1878, the Johns Hopkins University Press is America’s oldest university press and one of the world’s largest, publishing 70 scholarly journals and nearly 200 new books each year. The Press also manages Project MUSE, the acclaimed online collection of scholarly journals that recently announced plans to add scholarly book content in 2012.

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6 THE GAZETTE â&#x20AC;˘ April 25, 2011

Research sheds light on aneurysm growth, treatment in Marfan

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he Johns Hopkins researchers who first showed that the commonly used blood pressure drug losartan may help prevent lifethreatening aneurysms of the aorta in patients with Marfan syndrome have now discovered new clues about the precise mechanism behind the drugâ&#x20AC;&#x2122;s protective effects. The teamâ&#x20AC;&#x2122;s findings not only answer many lingering questionsâ&#x20AC;&#x201D;including how exactly the drug works and whether other classes of blood-pressure medication may work as well as or better than losartanâ&#x20AC;&#x201D;but also identify new targets for treating Marfan and other connective-tissue disorders. In two separate papers published in the April 15 issue of Science, the researchers show that losartan neutralizes a rogue protein and in doing so halts the dangerous ballooning of the heartâ&#x20AC;&#x2122;s main blood vessel, the aorta. â&#x20AC;&#x153;Our research has decoded the exact cascade of events triggered by the genetic glitch in Marfan that culminates in weakening of the aorta, its gradual enlargement and tearing,â&#x20AC;? said senior investigator Harry â&#x20AC;&#x153;Halâ&#x20AC;? Dietz, a cardiologist at the Johns Hopkins Childrenâ&#x20AC;&#x2122;s Center and a professor in the McKusick-Nathans Institute of Genetic Medicine and director of the William S. Smilow Center for Marfan Research, both in the Johns Hopkins School of Medicine. â&#x20AC;&#x153;Understanding the cellular cascade leading up to Marfanâ&#x20AC;&#x2122;s most serious complication will allow us to design therapies that

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precision-target each step in this harmful sequence of events,â&#x20AC;? Dietz said. Dietzâ&#x20AC;&#x2122;s research has previously shown that the dangerous stretching of the aorta in those born with the genetic disorder stems from the excessive activity of a protein called TGF-beta, believed to cause damage by setting off aberrant signals inside cells that make up blood vessels. The new research, conducted in mice that were genetically engineered to develop Marfan, identifies one of these signals as a critical communication channel that sets off a dangerous cross talk between TGF-beta and a protein called ERK. TGF-beta activates ERK, which causes the aorta to stretch and grow aneurysms, the researchers found. The research further shows that two other proteins, AT1 and AT2, play opposing roles in the cross talk between TGFbeta and ERK, and that turning one off while keeping the other intact is critical in preventing aneurysms. Researchers have long suspected that AT1 can cause damage to the aorta by activating TGF-beta, but AT2â&#x20AC;&#x2122;s role has remained unclearâ&#x20AC;&#x201D;until now. To explain the role of AT2 in aneurysm formation, the researchers treated mice with Marfan with either losartan, a known inhibitor of AT1, or enalapril, a drug that shuts off both AT1 and AT2. The aortas of mice treated with losartan stopped growing in the area where aneurysms tend to form. Mice treated with enalapril, however, showed barely any improvement. The discovery led researchers to conclude that blocking the AT1 alone can slow growth and avert aneurysm formation, but blocking both AT1 and AT2 would not. In other words, keeping AT2 intact halted the dangerous interplay between TGF-beta and ERK. Losartan blocked AT1 but spared AT2, thus turning off ERK. Enalapril shut off both and had no effect on ERK. Because TGF-beta is already a suspect in other connective-tissue diseases, these new revelations about its modus operandi may pave the way to new therapies for such disorders, the investigators said. â&#x20AC;&#x153;Precision-targeting AT1 to shut it off while leaving AT2 intact is the way to go,â&#x20AC;? said lead author Jennifer Pardo Habashi, a cardiologist at Hopkins Childrenâ&#x20AC;&#x2122;s. â&#x20AC;&#x153;Now that we know what makes losartan so effective, we can start looking for other medications that may be even better at preventing aortic damage.â&#x20AC;? The investigative team also tested a candidate compound that selectively blocks ERK and showed that it completely halted aneurysm growth in mice with Marfan. Yet another compound that blocks another one of TGF-betaâ&#x20AC;&#x2122;s communication channels, called JNK, was nearly as effective in curbing aneurysm growth. Dietz identified the Marfan gene in the 1990s and led the scientific team that in 2006 first described losartanâ&#x20AC;&#x2122;s effect on the aorta. A small Johns Hopkins study in children has already shown that losartan can slow enlargement of the aorta over time. Based on these findings, larger clinical trials are already under way at Hopkins Childrenâ&#x20AC;&#x2122;s and other institutions. Other Johns Hopkins researchers involved in the two studies are Tammy Holm, Jefferson Doyle, Djahida Bedja, Yi Chun Chen, Christel van Erp, Hamza Aziz, Mark Lindsay, David Kim, Daniel Judge, Alexandra Modiri, Florian Schoenhoff and Ronald Cohn. Co-investigators from other institutions are Bart Loeys, of Ghent University in Belgium; and Craig Thomas, Samarjit Patnaik and Juan Marugan, all of the National Institutes of Health. The research was funded by the National Institutes of Health, Howard Hughes Medical Institute, Smilow Center for Marfan Research at Johns Hopkins and The National Marfan Foundation.

April 25, 2011 • THE GAZETTE

SAIS and INSEAD launch dual-degree program

he Johns Hopkins University Paul H. Nitze School of Advanced International Studies, a top international relations graduate school, and INSEAD, the leading international business school, last week announced an agreement to establish a dual-degree program. The new offering will allow students from both schools to work toward completing the SAIS Master of Arts and INSEAD Master of Business Administration simultaneously. The INSEAD-SAIS Dual-Degree Program will prepare students for careers that combine international relations and business administration. Students admitted to both programs will be able to complete the two degrees in two and a half years—instead of the three years required to complete the degrees separately—by

spending one and a half years at SAIS and one year at INSEAD. Dipak C. Jain, dean of INSEAD, said, “We share a similar vision with SAIS to develop globally minded leaders in business and beyond. The INSEAD-SAIS Dual-Degree Program will be especially valuable for those who seek management responsibilities in international corporations, financial institutions, economic and development institutions, and government agencies.” For students accepted in the program, SAIS will reduce the number of required courses from 16 to 12 in recognition of course work taken at INSEAD; all graduation requirements must be completed within these 12 courses. Those completing the INSEAD MBA must take five periods of course work for a total of 23.5 courses, including 13 core courses and 10.5 elective courses. “SAIS is pleased to be part of this new

relationship,” said SAIS Dean Jessica P. Einhorn. “It will be beneficial not only to participating dual-degree students but to the SAIS community as a whole, as we add to the diversity of students and interests. We are confident that, with INSEAD as our partner, the students who pursue dual degrees will find that the whole is greater than the sum of such excellent parts, and doors will open for superb careers of international engagement.” Participants may begin the program at either SAIS or INSEAD. At SAIS, students can start in either Washington, D.C., or Bologna, Italy, with the final (third) semester being in Washington. At INSEAD, students can start in either Fontainebleau, France, or Singapore, and can thereafter exchange between the two campuses, as well as participate in exchanges with the University of Pennsylvania’s Wharton School and Northwestern University’s Kellogg School of Management.

Fungus reveals clue to immune system protection

discovery by Johns Hopkins scientists about how a single-celled fungus survives in low-oxygen settings may someday help humans whose immune systems are compromised by organ transplants or AIDS. A report on the discovery in a yeast called Schizosaccharomyces pombe appears April 22 in Molecular Cell. Previous work by the Johns Hopkins team showed that Schizosaccharomyces pombe, a model organism that’s often used to study individual genes, contains a protein named Sre1 that allows the organism to adapt to conditions in which oxygen is very low or missing altogether. To find out what regulates Sre1, the

researchers turned to their collection of 2,626 individual strains of fission yeast, each of which is modified to lack a different gene from the organism’s genome. First, they subjected each of the mutant strains to low-oxygen conditions and identified 28 genes whose absence stopped the yeast from growing. Four of the mutants regained their ability to grow in low oxygen when the scientists added back Sre1. “Unless something removes it, Sre1 stays attached to the cell membrane and therefore is unable to travel to the nucleus to do its job,” said Peter J. Espenshade, an associate professor of physiology and a member of the Center for Metabolism and Obesity Research at the Johns Hopkins University

School of Medicine. “Only when cut and released from the membrane can Sre1 go to work.” To find that cutting mechanism, the researchers examined the four mutant yeast strains, looking for evidence of the molecular machinery that allows the short, active “business part” of Sre1 to make its way to the nucleus of the cell to turn on genes. Cells that can’t cut Sre1 to activate it look and fare just like those that are completely missing it, Espenshade said. The team identified four genes called defective for Sre cleavage, or dsc 1-4, and showed that they are responsible for making the protein components of the cutting mechanism, a so-called Dsc E3 ligase com-

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“There is a clear need for students to have a sophisticated understanding of both international affairs and management issues in an increasingly complex and interdependent world,” said Jake Cohen, dean of INSEAD’s MBA program. “The INSEAD-SAIS dual degree provides a unique international framework for students who envision global careers in a fast-changing world.” Only students in the SAIS MA program studying at the SAIS Washington or Bologna campuses and students in the INSEAD MBA program enrolled at the school’s Fontainebleau or Singapore campuses will be eligible to participate in the dual-degree program. Career and student services will be available from the time the student matriculates at either institution until completion of the program.

plex that resides in a compartment of the cell called the Golgi. Sre1 is required for virulence in diseasecausing fungi such as Aspergillus fumigatus, which ravage people whose immune systems have been weakened by cancer or infections. The dsc 1-4 genes, according to Espenshade, are conserved in Aspergillus as well as a number of other fungi that cause a range of diseases. “Our studies suggest that dsc proteins are an attractive target for the development of new drugs to combat fungal infections in immune-compromised people,” Espenshade said. The research was supported by the National Institutes of Health and Burroughs Wellcome Fund. Authors on the paper from Johns Hopkins, in addition to Espenshade, are Emerson V. Stewart, Christine C. Nwosu and Zongtian Tong. —Maryalice Yakutchik

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8 THE GAZETTE • April 25, 2011

COURTESY OF LENA DENIS

April 25, 2011 • THE GAZETTE

Lena Denis in Dougga, an ancient Roman city in northern Tunisia that is now a UNESCO World Heritage Site. Behind her is the town’s amphitheater. The remote city, one of the best-preserved Roman cities in existence, was hidden behind a rock outcropping so that invaders couldn’t find it easily. Denis took a three-hour ride, in two taxis, from the nearest city to get there.

Journey Continued from page 1 Hong said. “She was like, I don’t know. We usually just say ‘it’ or ‘that thing.’” They ultimately had to consult a Chinese/English dictionary. Hong, from Santa Rosa, Calif., wondered if modern-day Chinese youth still clung to this unwritten gag order on sexual topics and, if so, what impact the cultural attitude had on sexual health. She would find the answer and more thanks to a Woodrow Wilson fellowship award she received her sophomore year. Since 1999, Woodrow Wilson fellowships have allowed undergraduates in the Krieger School of Arts and Sciences the opportunity to pursue an independent research project over the course of their college career. Hong is one of 19 seniors who on Friday, April 29, will discuss the results of their research at a poster session to be held from 3 to 6 p.m. in Homewood’s Glass Pavilion. Subjects of other Woodrow Wilson projects on display at the Friday poster session include an assessment of a high-speed rail system across the United States; the potential for tobacco cessation clinics in a poor community in Cape Town, South Africa; bureaucratic barriers to health care in Baltimore; and a fantasy-tinged play written, produced and directed by a fellow and staged in Chicago. Hong, during her junior year, studied abroad at Peking University, where she conducted a survey of 176 students on their sexual health knowledge and the associated cultural stigmas and access to care. The survey found that a large majority of students knew only one of the four modes of HIV transmission. When students were asked how they would feel if they found out a friend was HIV positive, nearly 70 percent of respondents said that it would have a severe or somewhat negative effect on their friendship. Only three students reported ever using sexual health services at a clinic or hospital. In addition to conducting the universitybased survey, Hong found time to venture into China’s countryside to research reproductive health and the impact of the nation’s one-child policy, and soak up as much of the culture as she could. As in years past, the Woodrow Wilson awards let students not just explore topics but explore the world. Hong said she was somewhat surprised to uncover just how uninformed Chinese college-age students were about HIV and other sexually transmitted diseases. “Not only could they not pick out the actual ways to transmit HIV from one person to another, they picked out modes that were incorrect, like hugging or sharing food,” Hong said. “There is a lot of mis-

conception out there and a lot of negative attitude toward HIV-infected individuals.” She witnessed the stigma firsthand when she visited a health clinic in Beijing. Doctors she spoke with said they could easily pick out who was there for HIV testing— they would be the individuals who waited until everyone was gone from the waiting room to ask to be seen. “In China, not everyone comes in with an appointment,” she said. “And when you’re standing in line, you have to tell the person what you’re there for. When they do the testing, everyone else can see.” Many primary and secondary schools in China strongly discourage students from having sexual or even romantic relationships, Hong said. Sexual education is taught in middle schools, but Hong learned that most of the teachers are embarrassed to discuss the subject in class and assign the related chapter at home. Hong said that while many students knew the word for sex, the topic was not discussed openly outside of sexual education courses taught in college. Hong said that the ramifications of this lack of knowledge and discourse could mean a steady increase in HIV and STD transmission. “I think there needs to be more dialogue, and students need more information on how to access resources,” she said. “Out of the people I surveyed, only 2 percent actually use sexual or reproductive health services if they do need them, which I found shocking. Even if people weren’t admitting to me that they were going, it’s still likely a very low number.” Speaking of what she learned, Hong said that the experience has given her a newfound confidence. “I feel that now I’m much more open to ask questions and reach out to people,” she said. “I’m not afraid to go after what I want. I also realize you don’t need a PhD to explore what you’re interested in. You can start right now.” The annual Woodrow Wilson Undergraduate Research Fellowship Program allows students to delve into unconstrained research during their undergraduate experience, mentored by a faculty member. Each Wilson fellow receives a grant of $10,000 to be distributed over four years to support research expenses, including costs associated with travel, equipment and use of archives. The fellowships are given to incoming freshmen of outstanding merit and promise and also to rising sophomores, who receive $7,500 for three years. For high school seniors, a Woodrow Wilson brochure is included in the application packets mailed out by the Office of Undergraduate Admissions. Current freshmen, however, must submit a two-to-three-page proposal, a resume, a second-semester transcript and a letter of recommendation from a JHU faculty member who would become the student’s mentor.

The award is named after the former U.S. president, who received his doctorate from Johns Hopkins. The program was developed for the School of Arts and Sciences by Herbert Kessler, then dean of the school and now a professor of art history; Steven David, vice dean for undergraduate education; and university trustee J. Barclay Knapp, who funded the fellowships through the school’s James B. Knapp Deanship, named for his late father. Recipients have gone on to win Rhodes, Marshall, Fulbright and Truman scholarships. The individual research projects are designed by the fellows, and each student has the choice of focusing on a single longterm project, exploring several aspects of a particular discipline or working on various short-term undertakings in an array of fields. Students can opt to pursue research in their own major or, if they wish, branch off into a totally unrelated discipline. Lena Denis stuck to her major for her research on a terra cotta tile from the university’s Archaeological Museum. Denis, who is majoring in anthropology and history of art, wanted to trace the tile’s iconography and material to figure out where and why it was created. Her research required her to travel through Europe and North Africa, in addition to many hours of source reading. The roughly 10-by-12-inch tile depicts a stag drinking water from perhaps a stream or river. She came across the piece during her work at the Archaeological Museum, where she helped inventory many objects. Eunice Maguire, then curator of the Johns Hopkins Archaeological Collection, told Denis that not much was known about the tile and that she would love to learn more. Denis leapt at the chance for some detective work. She went in knowing that the object was acquired by Harry Langford Wilson, a professor of Roman archaeology and epigraphy who obtained more than 1,000 Etruscan and Roman artifacts for the university’s collection between 1906 and 1909.

During the summer after her junior year, Denis traveled to London to visit the British Museum, which holds a wealth of mosaics and terra cotta pieces. There she spoke with curators to discuss the tile’s stag image and material. She conducted similar research at the Louvre Museum in Paris. She would later travel to Tunisia, an area renowned for its terra cotta manufacture. She visited the ruins of Carthage, where she made a major breakthrough in her work. “I was standing in this chapel, and so many of the tiles set into the walls had deer images on them,” Denis said. “I was delighted.” She now believes the tile’s image demonstrates an important iconographic and stylistic shift in Early Christian art, one that ultimately influenced the early church’s theological understanding of salvation. As for where and when the tile was manufactured, Denis said it was likely made sometime in the fifth or sixth century in Italy. Denis said that her Woodrow Wilson experience confirmed what she wants to do the rest of her life: more of this same type of work. “I loved this opportunity to delve into world history and help understand religious works of art,” she said. “And it was such a great experience to do this travel.” Steven David, who is director of the Woodrow Wilson fellowship awards program, said that many fellows describe the research experience as their “defining moment” at Johns Hopkins. “They fully appreciate the opportunity to do these projects and get to know faculty that much better,” he said. “The experience also helps them in their future endeavors. For one, they stand out among graduate school applicants since they’ve had this opportunity to conduct a well-defined research project as an undergraduate. It just opens doors.” For current freshmen, the deadline for fellowship applications is May 13. For more information, go to www.jhu.edu/ woodrowwilson. G

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10 THE GAZETTE • April 25, 2011

By Greg Rienzi

The Gazette

n Jessica Anya Blau’s well-received debut novel, a 14-year-old girl named Jamie must navigate the choppy waters of adolescence amid a backdrop of sex, cigarettes, surfers, tanning and free-spirited parents who unabashedly sit poolside au naturel. In the book, set in Santa Barbara during the summer of 1976, Jamie rebels against her parents’ inflated open-mindedness and her friends’ search for boys and the perfect tan. The Summer of Naked Swim Parties supposedly contains elements from Blau’s own childhood growing up in Southern California. How closely does Jamie’s life parallel that of the author, a 1995 graduate of The Johns Hopkins University’s Writing Seminars? Why not ask her yourself. Blau will be among the 39 featured guests at the inaugural Alumni Authors Book Fair to be held from 9 to 11 a.m. on Saturday,

AAAS Continued from page 1 the Woodrow Wilson School of Public and International Affairs and the Department of Sociology. Previously, during eight years at Harvard University, she was the first dean of social science at the Radcliffe Institute for Advanced Study. In addition, Newman has served on the faculties of Columbia University and the University of California, Berkeley. Newman has focused much of her scholarship on the lives of the working poor and on mobility up and down the economic ladder. She has investigated the impact of tax policy on the poor, school violence, the history of public opinion’s impact on poverty policy and the impact of globalization on young people in Italy, Spain, Japan and

April 30, in the Great Hall of Levering Hall on the Homewood campus. The authors represent a variety of genres in the worlds of fiction and nonfiction. Many of those scheduled to attend came through the university’s Writing Seminars or had works published by the Johns Hopkins University Press. The event, which is free and open to the public, will give participants an opportunity to discuss the world of print and publication with authors who know the highs of acceptance and lows of rejection. Event organizer Judy Fusting, an associate in the Office of Alumni Relations, says that the fair should appeal to bibliophiles and budding authors alike. “This is certainly a great opportunity for current students with an interest in writing to speak with a published author,” she said. “We also think it’s a great service for alumni and a chance to give our growing number of authors greater exposure.” The list of alumni scheduled to attend includes Sujata Massey, author of the mystery series featuring amateur sleuth Rei

South Africa, among other topics. She has written or co-authored 10 books and has several more in progress. Her newest book, Taxing the Poor: Doing Damage to the Truly Disadvantaged, was recently published by the University of California Press. Dang’s research has unraveled key functions of the MYC oncogene, establishing the first link between a cancer gene and altered cancer cell metabolism. His laboratory contributes and stimulates research on the age-old observation of altered sugar metabolism in cancers, which is now beginning to be exploited for cancer therapy. He has authored more than 200 papers, book chapters and monographs. A 1982 graduate of the School of Medicine, Dang joined the faculty in 1987 after completing a fellowship at the University of California, San Francisco and a residency at The Johns Hopkins Hospital. An expert in medieval history with a special interest in historiography and linguistic

WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Getting the word out

The inaugural Alumni Authors Book Fair welcomes 39 writers to the Homewood campus on Saturday and will also showcase JHU Press books by university alumni.

Shimura; Todd Cohen, whose A Patient’s Guide to Heart Rhythm Problems was named Library Journal’s Best Health Book for 2010; David Edelman, a science fiction author whose book Infoquake was Barnes & Noble’s Best Science Fiction Book of the Year in

2006; and Charles Euchner, who wrote Nobody Turn Me Around: A People’s History of the 1963 March on Washington. The Book Fair is sponsored by the Class of 1986. Books will be available for review and purchase.

analysis, Spiegel was elected president of the American Historical Association in 2007. She is the author or editor of four books and more than 40 academic articles. Her article “History, Historicism and the Social Logic of the Text in the Middle Ages,” which appeared in Speculum in 1990, has been hailed as one of the most important analyses of medieval historiography ever written, and as a critical intervention in debates over historians’ use of postmodern theory. The article has been widely reprinted, translated and commented upon, and won the article prize of the Berkshire Conference of Women Historians. She has held fellowships from the John Simon Guggenheim Memorial Foundation and the Center for Advanced Study in the Behavioral Sciences, among many other honors. This year’s 212 new AAAS fellows and foreign honorary members were nominated and elected to the academy by current members. A broad-based membership of scholars

and practitioners from mathematics, physics, biological sciences, social sciences, humanities and the arts, public affairs and business allows the academy to conduct a wide range of interdisciplinary studies and public policy research. Newman, Dang and Spiegel will be inducted on Oct. 1 in Cambridge, Mass., alongside other distinguished fellows, including singer-songwriters Leonard Cohen and Paul Simon, actors Helen Mirren and Sam Waterston, documentary filmmaker Ken Burns, French poet Yves Bonnefoy, University of Cambridge classicist Mary Beard, Tel Aviv University President Joseph Klafter and financier David de Rothschild. Newman, Dang and Spiegel join 44 other Johns Hopkins faculty members as fellows of the AAAS. A list is available online at webapps.jhu.edu/jhuniverse/information_ about_hopkins/facts_and_statistics/faculty_ honors/a_a_a_s_fellows. G

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April 25, 2011 • THE GAZETTE

Icy moon zaps Saturn with electron beams APL camera captures auroral activity between Enceladus and Saturn By Michael Buckley

Applied Physics Laboratory

cientists working with data from NASA’s Cassini mission—now in its sixth year of operations at Saturn— have discovered an electrical current running between Saturn and its moon Enceladus that creates an observable emission on the ringed planet. Don Mitchell, Cassini science team coinvestigator from the Johns Hopkins University Applied Physics Laboratory, first observed the current connection as a strong “bull’s-eye” emission in the middle of images snapped by the APL-built ion and neutral camera, known as INCA, on Cassini. “The ion beam seen by the camera appears at exceptionally high energy, between about 30,000 and 80,000 electron volts—surprising for an interaction with such a small moon,” said Mitchell, co-author of a paper on the research appearing in the April 21 issue of the journal Nature. This planet-moon connection also happens at Jupiter; Io, Europa and Ganymede all produce visible auroral footprints. “Accurately identifying the magnetospheric location of a source of auroral emission is very exciting,” said Chris Paranicas of APL, a Cassini scientist not directly involved with the study. “At Jupiter, the identification of the satellite footprints in the auroral region allowed scientists to connect the polar region with the equatorial one magnetically. This paper will give us a great reference point for future studies of Saturn’s aurora.” The ion beam set the stage for APL’s Abigail Rymer, a lead author of the study and a Cassini team scientist, to find evidence of a very strong co-aligned electron beam in Cassini plasma spectrometer data. “I immediately pulled up the electron data and, sure enough, there was a very strong electron beam propagating away from Saturn toward Enceladus,” Rymer said. “It was actually a fairly rare opportunity to capture

that, since when Cassini flies close to a moon, we are generally looking at the moon, not away from it.” The electrons Rymer discovered were of sufficient energy that they could stimulate an observable auroral output on the planet, a glowing spot formed the same way as the Earth’s northern lights—with electrons precipitating into the ionosphere. At Earth, however, the electrons come from interplanetary space; at Saturn, they represent an enormous current system looping through Enceladus all the way back to Saturn, more than 150,000 miles away. Two weeks after the initial observations, with Cassini flying at higher latitudes, the ultraviolet imaging spectrograph captured three images of Saturn’s ionosphere that included a visible glowing spot at exactly the expected location. “We searched for an auroral footprint on Saturn by using Cassini’s ultraviolet spectrograph to make images,” said Wayne Pryor, the other study lead, of Central Arizona College. “It turns out that ultraviolet light from the Enceladus footprint is not always visible; in fact, of 282 images that could include the signal, only seven provide convincing evidence for a bright spot.” That the footprint appears to “flicker” suggests variable outgassing from Enceladus, Rymer said, but the Cassini team is not yet convinced the plume activity on Enceladus is variable. “Scientists have been wondering whether the venting rate is variable, and these new data suggest that it is,” Rymer said. The Cassini-Huygens mission is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. NASA’s Jet Propulsion Laboratory, a division of the California Institute of Technology in Pasadena, Calif., manages the mission for NASA’s Science Mission Directorate, in Washington, D.C. The ultraviolet imaging spectrograph team is based at the University of Colorado, Boulder. The magnetospheric imaging team is based at the Johns Hopkins University Applied Physics Lab, in Laurel, Md. The Cassini plasma spectrometer team is based at the Southwest Research Institute, San Antonio. For more information about the CassiniHuygens mission, go to saturn.jpl.nasa.gov and www.nasa.gov/cassini.

Jeffrey Gray named Faculty Scholar in Whiting School of Engineering

effrey Gray, associate professor in the Department of Chemical and Biomolecular Engineering, has been named the Whiting School of Engineering’s inaugural F. Stuart Hodgson Faculty Scholar. The award was established through a gift from alumnus F. Stuart Hodgson. After graduating from Johns Hopkins in 1967 with a degree in chemical engineering, Hodgson went on to a successful career in industry, eventually co-founding Defense Technology Inc., an industry leader in business consulting and technology management. Over the years, he has remained connected to the university and the Whiting School in several capacities, including service on ChemBE’s Visiting Committee and as an active member of the Johns Hopkins alumni community in Florida. A senior assistant professor or associate professor who exhibits exceptional achievement in their area of expertise is named a Faculty Scholar. For Gray, this award recognizes his research in areas that include biomolecular structure prediction and design, protein-protein docking, therapeutic antibodies and protein-solid surface interaction, as well as his role as a teacher and mentor. Faculty Scholar status is awarded for a

three-year term to provide selected faculty with flexible financial support to promote their innovative research, teaching activities and entrepreneurial thinking.

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12 THE GAZETTE • April 25, 2011

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April 25, 2011 • THE GAZETTE A P R I L

2 5

–

M A Y

vestigator of the rotavirus vaccine. E2014 SPH. EB

Calendar Continued from page 16 performs Beethoven’s Eroica symphony and Walton’s Partita, with guest conductor Leon Fleisher. (See In Brief, p. 2.) $15 general admission, $10 for senior citizens and $5 for students with ID. Friedberg Hall. Peabody Shriver Hall Concert Series presents the Tokyo String Quartet with Leon Fleisher, piano. (See photo, p. 16.) $38 general admission, $19 for non-JHU students; free for JHU students. Shriver Hall. HW Sun., May 1, 5:30 p.m.

Peabody Preparatory recital, featuring the winners of the Preparatory PartRecital Competition. Cohen-Davison Family Theatre. Peabody

Sun., May 1, 7:30 p.m.

The Peabody Opera Workshop presents “Handel’s Heritage,” a program of scenes from Handel and his operatic predecessors. Friedberg Hall. Peabody Mon., May 2, 7:30 p.m.

REA D I N G S / B OO K TAL K S

The Writing Seminars presents Rosanna Warren, reading from Ghost in a Red Hat, her fifth collection of poems. Mudd Auditorium. HW

Tues., April 26, 6:30 p.m.

Baltimore-based author Madison Smartt-Bell will discuss and sign copies of his latest novel, The Color of the Night. Barnes & Noble Johns Hopkins. HW

Wed., April 27, 7 p.m.

Loyola professor and Baltimore author Mark Osteen will discuss and sign copies of his book, One of Us: A Family’s Life With Autism. Barnes & Noble Johns Hopkins. HW Mon., May 2, 7 p.m.

S E M I N AR S

Mon., April 25, noon. “Roles of Androgen-Responsive Genes in Prostate Cancer,” a Biochemistry and Molecular Biology seminar with Zhou Wang, University of Pittsburgh Cancer Institute. W1020 SPH. EB Mon., April 25, 12:10 p.m.

“Road Safety in Latin America,” a Graduate Seminar in Injury Research and Policy with Eugenia Rodriguez, Pan American Health Organization. Sponsored by Health Policy and Management and the Center for Injury Research and Policy. W4013 SPH. EB Mon., April 25, 12:15 p.m.

“Making the Mouse Blastocyst— Cell Lineages to Stem Cells,” a Carnegie Institution Embryology seminar with Janet Rossant, University of Toronto. Rose Auditorium, 3520 San Martin Drive. HW Mon., April 25, 12:15 p.m.

“Community Engagement in Research,” a Berman Institute of Bioethics seminar with Jim Lavery, University of Toronto. 150

Armstrong Medical Education Bldg. EB Mon., April 25, 4 p.m. “Pharma-

ceutical Politics and Regulatory Reform in Post-War America,” a History seminar with Dominique Tobbell, University of Minnesota. 308 Gilman. HW

“Expected Euler Characteristic of Excursion Sets of Holomorphic Sections,” an Analysis/PDE seminar with Jingzhou Sun, KSAS. Sponsored by Mathematics. 302 Krieger. HW Mon., April 25, 4 p.m.

Tues., April 26, 10:45 a.m.

“The Voronoi Diagram of Points on a Surface: Surface, Medial Axis and Complexity,” a Computer Science seminar with Nina Amenta, University of California, Davis. B17 Hackerman. HW “The Influence of Sex Education on the Sexual Behavior of Jamaican Youth,” a Population, Family and Reproductive Health thesis defense seminar with Terri-Ann Thompson. E6519 SPH. EB

Tues., April 26, 2 p.m.

“How to Have Fun in Electricity and Environmental Policy Modeling,” a Geography and Environmental Engineering seminar with Ben Hobbs, WSE. 234 Ames. HW

Tues., April 26, 3 p.m.

Tues.,

April

26,

3:30

p.m.

“Mammalian Functional Genomics 2011—Like Kids in a Candy Shop?” a High Throughput Biology Center seminar with David Root, MIT and Harvard University. Mountcastle Auditorium, PCTB. EB Tues., April 26, 4 p.m. “ ‘Where Am I Supposed to Be?’: Incarceration, Theology and Pharmaceutical Landscapes,” an Anthropology seminar with Aaron Goodfellow, KSAS. 400 Macaulay. HW

“NIH Molecular Libraries Program and Beyond: Integrative Technologies Enabling Biology and Chemistry as a Collaborative Resource for Probe and Drug Discovery,” a Pharmacology and Molecular Sciences seminar with James Inglese, National Human Genome Research Institute. West Lecture Hall (ground floor), WBSB. EB Tues., April 26, 4 p.m.

Tues.,

April

26,

4:30

p.m.

“Building Watson: An Overview of DeepQA for the Jeopardy! Challenge,” a Center for Language and Speech Processing seminar with David Ferruci, IBM Research. B17 Hackerman. HW Wed., April 27, noon. “Local Signaling in Directed Cell Migration,” a Cell Biology seminar with Tobias Meyer, Stanford University. Suite 2-200, 1830 Bldg. EB

“Increasing Vaccine Delivery on a Global Level,” an International Health seminar with keynote speaker Mathuram Santosham, SPH, and guest speaker Paul Offit, co-inWed., April 27, noon.

Wed., April 27, 12:15 p.m.

Wednesday Noon Seminar— “Risk Factor for Schizophrenia Subtypes: Associations With Symptom Patterns and Course of Disorder in the Danish Registry” with Katie Nugent, SPH. Sponsored by Mental Health. B14B Hampton House. EB Wed., April 27, 1 p.m. “Project Achilles: Functional Genomics and Cancer,” a Johns Hopkins Technology Center for Networks and Pathways seminar with William Hanh, Dana Farber Cancer Institute and Harvard Medical School. Mountcastle Auditorium, PCTB. EB

“Conformational Exchange in Antiparallel EmrE: Insights Into the Mechanism of Multidrug Resistant Transport,” a Biophysics and Biophysical Chemistry seminar with Katherine Henzler-Wildman, Washington University School of Medicine. 701 WBSB. EB

Wed., April 27, 1:30 p.m.

Wed., April 27, 4 p.m. “rRNA Methylation by Radical SAM Methyltransferases,” a Pharmacology and Molecular Sciences seminar with Danica Fujimori, University of California, San Francisco. West Lecture Hall (ground floor), WBSB. EB Wed., April 27, 4 p.m. “Bayesian Borrowing of Information Across High-Dimensional Exposures and Outcomes,” a Biostatistics seminar with Amy Herring, University of North Carolina. W2030 SPH. EB Thurs., April 28, 10:45 a.m.

“De Novo Design of Self-Assembled Peptide Hydrogels for Delivery: Manipulating Peptide Structure to Modulate Material Properties,” a Chemical and Biomolecular Engineering seminar with Joel Schneider, NCI/NIH. 301 Shaffer. HW The Bromery Seminar—“What Banded Iron Formations Tell Us About the Precambrian Earth” with Kurt Konhauser, University of Alberta. Sponsored by Earth and Planetary Sciences. Olin Auditorium. HW

Thurs., April 28, noon.

“China, pH, a Fungal Pathogen and a Better Way to Kill Mosquitoes and Fire Ants,” a Biology seminar with Nemat Keyhani, University of Florida. 100 Mudd. HW

Thurs., April 28, 4 p.m.

Fri., April 29, 9 a.m. “Antimicrobial Resistant Bacteria and Use of Antimicrobials in Pig Farming in Peru,” an International Health thesis defense seminar with Carmen Arriola. W2030 SPH. EB

“High Performance Computing With CUDA,” a CEAFM seminar with Massimiliano Fatica, NVIDIA. 50 Gilman. HW

Fri., April 29, 11 a.m.

“Got Oxygen? SREBP Pathway: More Than Just Sterol Sensing in Fission Yeast,” a Carnegie Institution Embryology seminar with ChihYung Sean Lee, SoM. Rose Auditorium, 3520 San Martin Drive.

Fri., April 29, 12:15 p.m.

“Seeding Mobilization, Harvesting Support: Polarization and the Structuring of Collective Action in Chavez’s Venezuela,” a Program in Latin American Studies seminar with Michael McCarthy, KSAS. 113 Greenhouse. HW

Fri., April 29, 12:30 p.m.

Fri., April 29, 1 p.m. “Visualizing Immune Response to SIV Infection” with Adam Pellerite; “Hemoglobin Disorders Teaching Module” with Suzanne Slattery; and “Pancreatic Cancer Diagnostic Training Using the iPad” with Bona Kim, a Molecular and Comparative Pathobiology seminar with Art as Applied to Medicine graduate students. West Room (ground floor), BRB. EB

“RNA Structural Bioinformatics and Ontology,” a Biophysics seminar with Neocles Leontis, National Science Foundation. 111 Mergenthaler. HW

Mon., May 2, noon.

“U.S. Assistance in Injury Prevention,” a Graduate Seminar in Injury Research and Policy with Nancy Carter-Foster, U.S. State Department. Sponsored by Health Policy and Management and the Center for Injury Research and Policy. W4013 SPH. EB

Mon., May 2, 12:10 p.m.

Thurs., April 28, noon. “ ‘Un paralleled in the Realm’: Tea Utensils in 16th-Century Japan,” an East Asian Studies seminar with Andrew Watsky, Princeton University. 308 Krieger. HW

“Occupational Injuries That Fall Through the Cracks,” a Johns Hopkins Education and Research Center for Occupational Safety and Health seminar with Susan Baker, SPH. First in a series. W3008 SPH. EB

“Development of Anti-Pathogen Effector Genes for Control of Vector-Borne Diseases,” a Molecular Microbiology and Immunology/Infectious Diseases seminar with Anthony James, University of California, Irvine. W1020 SPH. EB

Mon., May 2, 12:15 p.m. “Maping Neural Circuits for Motor Sequences in Drosophila,” a Carnegie Institution Embryology seminar with Julie Simpson, Howard Hughes Medical Institute and Janelia Farms. Rose Auditorium, 3520 San Martin Drive. HW

“Dual Role of Sonic Hedgehog Signaling in Neurogenesis,” a Neuroscience research seminar with Sohyun Ahn, NICHD/NIH. West Lecture Hall (ground floor), WBSB. EB

Mon.,

Thurs., April 28, noon.

Thurs., April 28, 1 p.m.

Thurs., April 28, 3:30 p.m.

“Structural Basis of Decoding by the Ribosome,” a Molecular Biology and Genetics seminar with Venki Ramakrishnan, MRC Laboratory of Molecular Biology, Cambridge, UK. Mountcastle Auditorium, PCTB. EB

Mon., May 2, 12:10 p.m.

May

1:30

p.m.

“Mechanical Regulation of Epithelial Branching,” a Biomedical Engineering seminar with Celeste Nelson, Princeton University. 709 Traylor. EB (Videoconferenced to 110 Clark. HW ) The David Bodian Seminar—“The Side Matters: Why Line Drawings Only Confuse Us in Understanding Figure-Ground Perception” with Naoki Kogo, University of Leuven, Belgium. Sponsored by the Krieger

Mon., May 2, 4 p.m.

Mind/Brain Institute. 338 Krieger. HW Mon., May 2, 4:30 p.m. “Multilingual Subjectivity Analysis,” a Center for Language and Speech Processing seminar with Rada Mihalcea, University of North Texas. B17 Hackerman. HW

“Descartes’ Modal Epistemology,” a Philosophy seminar with Elliot Paul, NYU and Barnard College. 288 Gilman. HW

Mon., May 2, 5 p.m.

S P E C I AL E V E N T S

Fri., April 29, noon. “Sister to Sister: Pursuing Success,” the Black Faculty and Staff Association’s annual Women’s Luncheon/ Forum with guests—and sisters— Caroline Laguerre-Brown, vice provost for institutional equity at Johns Hopkins, and Roberta Laguerre-Frederique, St. Christopher’s Hospital for Children. Registration required by April 25; go to bfsa.jhu.edu, select “Events,” then “Women’s Forum.” Tickets are $10, no charge to current BFSA members and JHU students. Salon C, Charles Commons. HW Fri., April 29, 5 p.m. The 2011 Foreign Affairs Symposium— Global Citizenship: Re-examining the Role of the Individual in an Evolving World—in conjunction with the Johns Hopkins Alumni Association and the Office of the President, presents a Nobel Prize panel featuring two Hopkins Nobel laureates, Peter Agre and Carol Greider. Shriver Hall. HW

W OR K S HO P S

Tues., April 26, through Thurs., April 28, 8:30 a.m. to 3 p.m. “Deconvolution of

Pooled shRNA Library Screens Using Microarray Technology,” a Sigma-Aldrich workshop with various speakers. Cost is $590. For more information and to register, go to www.sigma.com/workshop. Mountcastle Auditorium, PCTB. EB The Center for Educational Resources sponsors a series of

workshops on the Blackboard 9.1 interface. The training is open to all faculty, staff and students in full-time KSAS or WSE programs who have administrative responsibilities in a Blackboard course. To register, go to www.bb.cer.jhu.edu. Garrett Room, MSE Library. HW •

Tues., April 26, 1 to 3 p.m. “Getting Started With

Blackboard.”

•

Wed., April 27, 10 a.m. to noon. “Communication

and Collaboration in Blackboard.” •

Fri., April 29, 10 a.m. to noon. “Assessing Student

Knowledge and Managing Grades in Blackboard.”

Thurs., April 28, 1 p.m. “Introduction to Sharepoint,” a Bits & Bytes workshop. To register, go to www.cer.jhu.edu/events.html. The training is open to Homewood faculty, lecturers and TAs; staff are also welcome to attend. Sponsored by the Center for Educational Resources. Garrett Room, MSE Library. HW

14 THE GAZETTE • April 25, 2011 P O S T I N G S

B U L L E T I N

Job Opportunities The Johns Hopkins University does not discriminate on the basis of gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or other legally protected characteristic in any student program or activity administered by the university or with regard to admission or employment.

Homewood

Office of Human Resources: Suite W600, Wyman Bldg., 410-516-8048 JOB#

POSITION

47621

Sr. Programmer Analyst (Development) Sr. Associate Director, Affinity Engagement Programmer Analyst Software Engineer Graduate Recruiter Director, Scholarships and Fellowships

47628 47700 47753 47755 47758

Schools of Public H e a l t h a n d N u r s i n g Office of Human Resources: 2021 East Monument St., 410-955-3006 JOB#

POSITION

44976 44290 44672 41388 44067 44737 44939 44555 44848

Food Service Worker LAN Administrator III Administrative Secretary Program Officer Research Program Assistant II Sr. Administrative Coordinator Student Affairs Officer Instructional Technologist Sr. Financial Analyst

School of Medicine

Office of Human Resources: 98 N. Broadway, 3rd floor, 410-955-2990 JOB#

POSITION

39157 42411 44926 44928 45074 45241 45275 45401 45465 45546 45658 45691 45692

Compliance Specialist Trainer Financial Analyst Basic Science Informationist II Basic Sciences Informationist III Sr. Research Service Analyst Sr. Research Program Coordinator II Laboratory Technician Compliance Specialist Trainer Compliance Specialist Trainer Research Service Analyst Sr. Research Program Coordinator II Immunohistotechnologist Research Program Assistant

47529 47534 47568 47638 47644 47676 47762 47837 47558 47636 47712 47845 47855

Research Technologist Laboratory Coordinator HR Specialist Collections Assistant Registration Manager Academic Program Coordinator Benefits Assistant Financial Manager Web Developer Budget Analyst Administrative Manager Sr. Systems Administrator Customer Service Coordinator

44648 44488 43425 43361 44554 44684 42973 43847 45106 45024 42939 42669 44802 44242 44661 45002

Assay Technician Research Technologist Research Nurse Research Scientist Administrative Specialist Biostatistician Clinical Outcomes Coordinator Sr. Programmer Analyst Employment Assistant/Receptionist Payroll and HR Services Coordinator Research Data Coordinator Data Assistant Budget Specialist Academic Program Administrator Sr. Research Program Coordinator Research Observer

45791 45901 46051 46256 46412 46536 46852 46942 46701 47032 47304 47383

Flow Cytometry Lab Manager IT Project Manager Sr. Research Data Analyst Quality and Innovation Coach Research Service Analyst Laboratory Manager Sr. Research Service Analyst Veterinary Technician Custodian Sr. Research Program Manager Administrative Coordinator Medical Simulation Training Technician Sr. Research Nurse Nurse Practitioner or Physician Assistant Data Assistant Financial Analyst Research Specialist

47413 47442 47465 47714 47788

This is a partial listing of jobs currently available. A complete list with descriptions can be found on the Web at jobs.jhu.edu.

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Notices

B O A R D

No notices were submitted for publication this week.

Unreliable measures hamper efforts to assure safer care Expert says that current ‘metrics’ don’t paint clear picture of quality By Stephanie Desmon

Johns Hopkins Medicine

ith a push to make hospitals and doctors more accountable for health care quality, more attention must be paid to the accuracy and reliability of measures used to evaluate caregivers, says a prominent Johns Hopkins patient safety expert. Writing in the April issue of the journal Health Affairs, Peter J. Pronovost, a professor of anesthesiology and critical care medicine in the School of Medicine, argues that as the desire to evaluate and improve health care intensifies, there remains little consensus as to which measures are scientifically valid and accurate assessments of quality. This risks misinforming patients who may make decisions based on metrics that poorly reflect the state of health care provided by hospitals, and may ultimately lead to a failure to make improvements in hospitals where quality is judged to be better than it is, he says. “There is bipartisan support behind efforts to start paying for value rather than volume,” Pronovost said. “This is great, but we act as if there’s a whole library of reliable outcome measures for us to use, and the fact is that serious work needs to be done to create them. We can’t shrink from doing this science. We need to be guided by it.” Acknowledging that substantial shortcomings in the quality of care persist— causing needless patient harm and increasing health care costs—Pronovost says that fixes can’t be put in place until rigorous scientific data show exactly where systems are broken, and until hard comparative evidence points to what types of repairs work best. In the absence of such safety and efficacy science, he says, there will remain little consensus among hospitals and physicians about the best methods to judge quality or improvement. For example, he notes that overall hospital death rates are an imperfect reflection of quality of care, but in some cases they are the only measures used. Pronovost, writing with Richard Lilford, an epidemiologist at University of Birmingham in England, points also to research that compared four different measurement services used to assess the same data from the same hospitals to determine in-hospital mortality. Forty-three percent of hospitals that showed higher-thanexpected mortality by one commercially available metric showed lower-than-expected mortality by another. Pronovost and Lilford call for the creation of an independent agency, the equivalent of a Securities and Exchange Commission for health care, to create rational and standardized outcome measures similar to the accounting rules the

SEC creates for businesses. “The goal is to make the process of determining quality standard and transparent, and make data meaningful for consumers and usable by clinicians, ultimately improving patient outcomes,” Pronovost said. Doctors support the use of outcome measures if they are valid and reliable enough to enable conclusions to be drawn about the quality of care, but too often they aren’t, Pronovost says. Hospitals, he notes, once were being fined for hospital bloodstream infections after government regulators, to calculate infection rates, screened billing claims for codes signifying infections. “That measurement gets it right only one in four times—25 percent of the time,” he said. “Clinicians have never used that data because they thought that it was useless, because it was useless.” Now, government regulators make judgments based on Centers for Disease Control and Prevention data, which include lab tests, temperature readings and other signs and symptoms of infection—far more accurate measures, he says. Meanwhile, Pronovost says that some states penalize institutions for what they deem are preventable complications contracted by patients during their hospital stays. But, he says, hospitals don’t know exactly what they are being judged on because those states use a proprietary algorithm created by a private company to determine which hospitals are “successful” and which ones should be sanctioned. Clinicians and the public know neither how accurate the measures are nor how they were calculated. “The process should be transparent and reproducible; instead, it’s a black box,” he said. “We don’t know if it gets it 5 percent right or 95 percent. We ought to know how imperfect it is.” In a second article published in Health Affairs, Pronovost and Johns Hopkins colleagues Jill A. Marsteller, of the Bloomberg School of Public Health, and Christine A. Goeschel, of Anesthesiology and Critical Care Medicine, present a case study of a success story in measuring outcomes: central line–associated bloodstream infections. The group outlines the Johns Hopkins–led effort to virtually eliminate bloodstream infections in intensive care units throughout Michigan, and which is now in nearly every state and has reduced the number of deaths. Infection rates have fallen dramatically in ICUs where Pronovost’s cockpitlike checklist and culture-of-safety program were implemented. This is one of the few, perhaps only, national success stories documenting measurable improvements in patient outcomes. The Johns Hopkins program is now being implemented across the United States. Data from the first 22 states that have participated in the program for longer than a year suggest infections have been reduced by approximately 40 percent. “There are precious few outcome measures deemed valid by clinicians,” Pronovost said. “This is one of them.”

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Read The Gazette online gazette.jhu.edu

April 25, 2011 • THE GAZETTE

Classifieds APARTMENTS/HOUSES FOR RENT Bolton Hill, 3BR Victorian brownstone, 3 full BAs, 1 half-BA, 2 kitchens, upgraded appls, W/D, top flr deck off master BR, hdwd flrs, backyd, prkng in rear, on quiet, cobbled street, email to request pics and arrange viewing. $1,910/mo. tymbuk2@gmail.com. Butchers Hill, great 2BR, 2.5BA RH, close to JHH, lots of storage, CAC, W/D, dw. Marc, 443-452-8088. Charles Village, luxury 2BR, 1BA apt, hdwd flrs, modern updated kitchen, CAC, off-street prkng, deck, avail June 1. $1,200/mo + utils. Christopher, 410-292-6656. Deep Creek Lake/Wisp, cozy 2BR cabin w/full kitchen, call for wkly/wknd rentals, pics avail at jzpics@yahoo.com. 410-638-9417. Ednor Gardens, clean, peaceful 3BR, 2BA house, W/D, dw, pets OK, close to JHU/JHMI, avail August 1. $1,400/mo. mLj260@nyu.edu. Federal Hill brownstone, 1BR, 1BA, dw, W/D, CAC/heat, hdwd flrs, pets OK, 1-car garage. $1,550/mo. cb_nd03@yahoo.com. Hampden, 3BR, 2BA TH, dw, W/D, nr lt rail. $1,100/mo + utils. 410-378-2393. Hampden, beautifully renov’d 3BR, 2BA duplex, eat-in kitchen, dw, master suite has own kitchen, W/D, clawfoot tub, covered storage bsmt, front/back porches, fenced backyd, ample street prkng, nr light rail, 1-yr lease. $1,500/mo + sec dep. Mina, 410-592-2670. Homeland, 2BR, 2BA condo in gated community, 15 mins to JHMI, renov’d kitchen and BAs, balcony, CAC, W/D, storage in bsmt, pool, exercise rm, prkng, avail May 15 (flexible). $1,300/mo incl heat. joanfreedman@ gmail.com. Homeland, 2BR, 2BA condo, CAC, W/D in unit, new kitchen appls, storage rm, community pool, fitness rm, security guard, 5 mins to JHU, 6-mo lease avail. $1,250/mo incl most utils. drew@mcproperty.com. Lake Lure, NC, 2BR mountain cabin, avail June 24-July 1, pools, golf, spa, tennis, more amenities. $800. 301-865-0610 or http:// rumblingbald.com. Locust Point (1325 Cooksie St), 2BR, 2BA house, W/D. $1,350/mo + utils. 410-4095136, 410-409-5137 or tmsroka@verizon.net. Mt Washington, stunning, short-term rental w/parquet flrs, patios, baby grand piano, 15 mins to JHU. $2,400/mo. 915-718-3180 or barbarakarni@gmail.com. Ocean City, 2BR, 2BA condo on 120th St, sleeps 6, immaculate, new appls, new flrs, living rm furniture, enclos’d courtyd, 2 short blks to beach, indoor/outdoor pools, tennis, racketball. 410-336-5369. Ocean City, Md, 3BR, 2BA condo on 137th St, ocean block, steps from beach, off-street prkng (2 spaces), lg pool, walk to restaurants/ entertainment. 410-544-2814. Patterson Park, 2BR, 2.5BA house on pleasant blk nr the park and JHMI, CAC, fin’d bsmt, fenced patio, pets negotiable. $1,200/ mo. Ursula, 410-381-5541. Rodgers Forge, 3BR TH w/new kitchen, AC, W/D, deck, no pets/no smoking, avail July 1. $1,650/mo. mtrblsd@gmail.com. Roland Park/Hampden, fully furn’d 4BR, 5BA house, W/D, patio, fenced yd, driveway, 1 blk Come one, come all -Free Parking! Sat., APRIL 30, 2011- eat in or carry out! 5 - 8 pm, $10/Dinner Children $6

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Greek Orthodox Cathedral of the Annunciation Corner of Maryland & Preston Streets

M A R K E T P L A C E

to Homewood campus and Rotunda, avail for 1 yr, July 2011 to mid-August 2012 (negotiable). $2,800/mo + utils. 410-366-4388. Stoneleigh, 3BR, 2.5BA house, 12-month lease starting July or August, rent deal contingent on caring for 4 cats (possibly 1 dog), only lg furniture will remain, nr great public school system, nr Homewood. $1,000/mo. Nicole Warren, 443-509-0552 or malimidwives@ gmail.com. Towson/Rodgers Forge, 3BR, 1.5BA TH, renov’d kitchen, W/D, CAC, deck, prkng pad, no smoking/no pets, avail May 15. $1,600/mo. wwang1268@yahoo.com. Towson-Stoneleigh school district, 3BR singlefamily house, avail May. shashaye@hotmail .com. University One, 1BR, 1BA condo w/balcony, 14th flr, renov’d kitchen and BA, avail July 2011. $1,500/mo incl utils. 410-274-0325. 108 W University Pkwy, fully furn’d 1BR summer sublet (June-August), at Homewood campus across from lacrosse field, walk to restaurants/ grocery stores, email for photos or to arrange a time to visit. $850/mo. 202-725-0233. 937 N Angel Valley Rd (Harford Co), 2BR, 1.5BA TH in quiet neighborhood. $1,100/mo. 561-543-2051 or symonia5@aol.com. Beautiful 3BR, 2BA condo w/garage, spacious, great location, walk to Homewood campus. $1,800/mo. 443-848-6392 or sue.rzep2@ verizon.net.

HOUSES FOR SALE Canton, beautifully renov’d 2BR, 2.5BA RH, huge master suite, open floor plan, rooftop deck, nr JHH/Bayview. 443-527-1643. Edgemere, 5BR waterfront house on .8 acre. $750,000. 410-830-1785. Gardenville, 3BR, 1.5BA RH in quiet neighborhood, new kitchen and BA, CAC, hdwd flrs, club bsmt w/cedar closet, maintenancefree yd, carport, 15 mins to JHH. $139,500. 443-610-0236 or tziporachai@juno.com. Mt Washington, 3BR, 2.5BA condo TH in scenic neighborhood, wood-burning fp, prkng, pool, patio, move-in cond, conv access to Hopkins. $179,000. missykhan@gmail.com. Silo Point, 1BR, 1.5BA condo, 1,324 sq ft, stainless steel appls, hdwd flrs, enjoy Sky Lounge, spa/fitness, nr I-95. $267,500 (+ $5,000 toward closing costs). 410-377-7489 or silopointcondo420@gmail.com. Springdale, 4BR, 2.5BA house, nr Dulaney High, walk to Loch Raven Reservoir. $370,000. 410-560-3556. Waverly, 4BR, 2BA TH, EOG unit, fin’d bsmt, wooden deck, fenced yd, great neighbors. $125,000. Randy, 410-456-3775 or randy@ homeownershipworks.com. Luxury 1BR condo in high-rise, secure bldg w/ doorman, W/D, CAC/heat, swimming pool, exercise rm, nr Guilford/JHU. $179,000. 757773-7830 or norva04@gmail.com. 3402 Mt Pleasant Ave, stunning, completed rehabbed house, nr everything in the city. $165,900. Pitina, 410-900-7436. 3612 Greenmount Ave, charming, renov’d 4BR house, over 1,900 sq ft, CAC, hdwd flrs, perfect home for entertaining, garage. $180,000. 410-812-9070.

Conn alto sax, best offer; exercise rowing machine, $50; excel cond. 410-488-1886.

ROOMMATES WANTED F nonsmoker wanted for master BR in 2-story, 2BR, 1.5BA condo in gated Mt Vernon community, prkng, avail July. $900/mo + 1/2 utils. tLsuber@gmail.com.

2005 Honda 450 dirt bike, in great cond. $2,500. 240-755-4954 or 443-423-3410.

Rms in furn’d Halethorpe house, W/D, backyd, park, nr MARC train/695/I-95, high-speed Internet, cable TV, short-term leases OK. $550/mo + utils. lizo99@hotmail.com.

SERVICES/ITEMS OFFERED OR WANTED

F nonsmoker wanted for 1BR w/priv BA nr medical campus. myhome.2011@yahoo.com. Furn’d 1BR in 3BR, 2BA apt in Fells Point, W/D, free Internet access, quiet street, best neighborhood, close to everything, free shuttle to SoM. $350/mo to $400/mo + utils. xzhan45@gmail.com.

Studios - $595 - $630 1 BD Apts. - $710-740 2 BD from $795

Hickory Avenue in Hampden!

2 BD units from $750 w/Balcony - $785!

Shown by appointment - 410-764-7776 www.BrooksManagementCompany.com

Couple looking to house-sit, happy pet- or plant-sit, responsible, experienced, w/references, avail June-August; compensation not necessary. 443-540-3964. Jerry and Lind Taylor Custom Tees, we design custom pillowcases, towels, sheet sets, teddy bears, T-shirts, logos, package deal for Class of 2011, at Northpoint flea market in Dundalk on Sat and Sun. Linda, 443-467-2833.

Big furn’d BR in new TH, walking distance to JHMI, nice neighborhood, pref nonsmoker/no pets. 301-717-4217 or jiez@jayzhang.com.

JHU International folk dance, Saturday nights, teaching 7:30-8:30pm, requests 8:30-10:30pm, 1st time free, $2 after that, Friends Meeting House, 3107 N Charles St.

Single F wants to share 2BR house w/same. 410-913-5801.

Mobile detailing and power wash service. Jason, 443-421-3659.

Unfurn’d BR and priv BA avail in 2BR, 2.5BA home, 2nd flr, share w/F prof’l and friendly dog, hdwd flrs, expos’d brick, fin’d bsmt, lots of extra storage space, sm patio in back, sec sys, street prkng. $600/mo + share of utils + sec dep. leannewolff@gmail.com.

Free vintage Steinway upright piano, built 1890, mahogany veneer, original ivories, beautiful exterior, playable but needs work; piano is heavy, must be moved by professionals. 202251-3972, rsbclark@comcast.net or http:// bit.ly/i2Gs6D (for pics).

Summer sublet: Rms in DeSoto Apts (across the street from Homewood campus on Greenway), 2 other roommates will be gone, you or group can have 3 available rms, cheap, spacious, good area. 321-501-0178.

College student available to house-sit for summer, long- or short-term, in Roland Park or Charles Village area. 443-848-3983. Graduate student offering house- or pet-sitting services for the summer. holly.michelle.wood@ gmail.com. Affordable, professional mobile auto detailing, we come to you. Erik, 443-934-3750.

CARS FOR SALE ’08 Honda Civic LX, silver, manual 5-spd, excel cond, original owner, 28K mi. $14,500. cfang77@gmail.com. ’99 Nissan Sentra, manual, in good cond, 97K mi. $2,500. 443-653-1876 or reaeg@yahoo .com.

ITEMS FOR SALE Antique bedroom dresser, beautiful oak, some inlay, 3-drawer, in great cond, nr JHU Homewood. $75. Judy, 410-889-1213 or judybyen@ hotmail.com. 2004 Harley Davidson Sportster XL883cc, silver, like new, garage-kept, less than 7K original miles, rarely driven, a “cream puff.” $3,500. 410-426-3150. Bassinet, Carter’s Soothe ’n’ Sleep, like new, w/2 sheets, only used a few times. $80. dmhart752003@yahoo.com. Sealy Posturepedic full-size mattress, boxspring and frame, $300; dresser w/tall mirror, $150; brown sleep sofa, $200; bookshelf w/movable panels, $60; wood desk, $100; office chair, $60; glass coffee table w/ black legs, $80; nightstand w/lamp, $50; TV stand, $30; storage cubes, $30. http:// tinyurl.com/3gg34au or sp4435@gmail.com. Guitar, Yamaha 12-string in excel cond. $200. wreisig4@comcast.net. Taylor commercial soft ice cream twist machine. $2,500/best offer. bawlmerhon@ yahoo.com. Dinette set, octagonal table w/4 chairs, blond/ black, you haul. $120. 443-983-2362.

Masterpiece Landscaping: knowledgeable, experienced individual, on-site consultation, transplanting, bed preparation, installation, sm tree and shrub shaping; licensed. Terry, 410-652-3446. Peabody grad student offering private French horn/trumpet lessons for affordable rates. shonagleopold@gmail.com. Friday Night Swing Dance Club, open to public, great bands, no partners needed. 410-6630010 or www.fridaynightswing.com. Affordable and professional landscaper/certified horticulturist available to maintain existing gardens, also designing, planting or masonry; free consultations. David, 410-683-7373 or grogan.family@hotmail.com. Need help with your JHU retirement plan investments portfolio? Free consultation. 410435-5939 or treilly1@aol.com. Tutor for all subjects/levels; remedial and gifted; also help w/college counseling, speech and essay writing, editing, proofreading, database design and programming. 410-337-9877 (after 8pm) or i1__@hotmail.com. Volunteer needed for ambitious ecology project. Mark, 410-464-9274. Great photos! Headshots for interviews/auditions, family pics, production shots, weddings or other events. Edward S Davis photography and videography. 443-695-9988 or esdavisimaging@gmail.com. Licensed landscaper avail for spring/summer lawn maintenance, yd cleanup, other services incl’d fall/winter leaf and snow removal, trash hauling. Taylor Landscaping LLC. 410-8126090 or romilacapers@comcast.net.

PLACING ADS Classified listings are a free service for current, full-time Hopkins faculty, staff and students only. Ads should adhere to these general guidelines:

HICKORY HEIGHTS WYMAN COURT • One ad per person per week. A Just Renovated! A lovely hilltop setting on

Beech Ave. adj. to JHU!

new request must be submitted for each issue. • Ads are limited to 20 words, including phone, fax and e-mail.

• We cannot use Johns Hopkins business phone numbers or e-mail addresses. • Submissions will be condensed at the editor’s discretion. • Deadline is at noon Monday, one week prior to the edition in which the ad is to be run. • Real estate listings may be offered only by a Hopkins-affiliated seller not by Realtors or Agents.

(Boxed ads in this section are paid advertisements.) Classified ads may be faxed to 443-287-9920; e-mailed in the body of a message (no attachments) to gazads@jhu.edu; or mailed to Gazette Classifieds, Suite 540, 901 S. Bond St., Baltimore, MD 21231. To purchase a boxed display ad, contact the Gazelle Group at 410-343-3362.

16 THE GAZETTE • April 25, 2011 A P R I L

2 5

–

M A Y

Calendar

an International Reporting Project at SAIS panel discussion with IRP fellows Jenny Asarnow, Jill Braden Balderas, Ann Kim, Annie Murphy and David Taylor. Co-sponsored by the Woodrow Wilson Center for International Scholars’ Environmental Change and Security Program and Africa Program. For information or to RSVP, email ecsp@wilsoncenter .org. Woodrow Wilson Center, 1300 Pennsylvania Ave., NW, Washington DC.

B LOO D D R I V E S

Mon., April 25, through Wed., April 27, 7:30 a.m. to 5 p.m.

JHU/American Red Cross blood drive. For eligibility requirements, go to www.hopkinsworklife.org/ community/blood_drive_locations .html. To schedule a donation, call 410-550-0289. Francis X. Knott Conference Center. Bayview

“Is the State Dead? A New History of the State,” a SAIS Global Theory and History Program discussion with Charles Maier, Harvard University. For information or to RSVP, email sLee255@jhu.edu or call 202-6635714. 812 Rome Bldg. SAIS

Thurs., April 28, 5 p.m.

C OLLO Q U I A

Tues.,

April

26,

4:15

Fri., April 29, 1 p.m. “Anticipatory Governance: Uniting Foresight and Policy,” a SAIS Energy, Resources and Environment Program discussion with Leon Fuerth, George Washington University. For more information or to RSVP, email eregloballeadersforum@jhu.edu. Rome Auditorium. SAIS

p.m.

“Ligands Which Provide Hydrogen Bonds Near and Far From the Metal Center,” a Chemistry colloquium with Elizabeth Papish, Drexel University. 233 Remsen. HW Wed., April 27, 3:30 p.m. “A Lensing Map … A Redshift Survey,” an STSci colloquium with Margaret Gellar, Center for Astrophysics. Bahcall Auditorium, Muller Bldg. HW

J. HENRY FAIR

LE C TURE S

Thurs., April 28, 3:45 p.m.

“Locating Agreement in Grammar,” a Cognitive Science colloquium with Rajesh Bhatt, University of Massachusetts, Amherst. 134A Krieger. HW

C O N FERE N C E S

“Stress and the Brain: Implications for Health, Development and Learning,” an Urban

Health Institute conference, cosponsored by the School of Education, the Brain Science Institute, the Ludwig Family Fund and the JHU Council for PK-12 Education. Registration fee is $150; to register, go to http://tinyurl.com/ 4hLp984. For information, email ccombs@jhu.edu. •

Thurs., April 28, 4:30 to 6 p.m. “Overcoming Adver-

sity: Resilience in Children,” keynote address by Sir Michael Rutter, King’s College London and Maudsley Hospital. Free to public; registration required. Reception follows. 110 Hodson. HW

•

Fri., April 29, 8 a.m. to 4:30 p.m. Areas of discus-

sion include prenatal and infancy, early childhood and middle childhood/adolescence, with various speakers. Turner Auditorium. EB

DISCUSSIONS/ TAL K S

Mon., April 25, 9 a.m. to 3 p.m.

“Plausibility of Malaria Eradication Given Our Current Tools and the Possible Development of Eradication Tools,” a Johns Hopkins Malaria Research Institute panel discussion and poster session in recognition of World Malaria Day. Registration required; go to http:// malaria.jhsph.edu/events/2010/ world%20malaria%20day%20 2011/worldmalariadayspeaker .index. E2030 SPH. EB

Renewal in Ancient West Mexico,” a student forum. 211 Hodson. HW

Shriver Hall Concert Series concludes its 45th anniversary season with encore performances by the Tokyo String Quartet, above, and pianist Leon Fleisher. See Music.

Mon.,

April

25,

4:30

p.m.

The Provost’s Lecture Series— “The Epigenetic Basis of Common Human Disease” by Andrew Feinberg, SoM. Q&A session and reception to follow. RSVP to provostrsvp@jhu.edu. 50 Gilman. HW

Mon., April 25, 12:30 p.m. A discussion of The Origins of Political Order: From Prehuman Times to the French Revolution, a new book by Francis Fukuyama of SAIS, with Fukuyama; Adam Garfinkle, editor, The American Interest; Michael Woolcock, World Bank; and Cinnamon Dornsife (moderator), SAIS. (See In Brief, p. 2.) A live webcast will be accessible at www .sais-jhu.edu. For more information or to RSVP, email saispubaffairs@ jhu.edu or call 202-663-5648. Kenney Auditorium, Nitze Bldg. SAIS Mon., April 25, 6:30 p.m. “The Future of Teaching: New Common Core Standards, New Assessments and New Evaluations—What Does It All Mean for Students and Teachers?” a School of Education panel discussion with Randi Weingarten, president, American Federation of Teachers; Michael Cohen, president, Achieve Inc.; Richard Lemons, Education Trust; and Sonja Brookins Santelises, Baltimore City Public Schools. Q&A session will follow. Part of the Shaping the Future series. To RSVP, go to www .education.jhu.edu/shaping_ future/index.html. Shriver Hall Auditorium. HW Tues.,

Peace Corps at 50: How Far Will You Go?” a SAIS International Development Program panel discussion with Kevin Quigley, president, National Peace Corps Association; Jill Miller, IREX; and Matthew Breman, Chemonics. For information or to RSVP, email sais.rpcv@gmail.com. Kenney Auditorium, Nitze Bldg. SAIS

“The Globalization Paradox, Democracy and the Future of the World Economy,” a Bernard L. Schwartz Forum on Constructive Capitalism with Dani Rodrik, Harvard University. Co-sponsored by the SAIS International Development Program. For information or to RSVP, email rbwashington@jhu.edu or call 202-663-5650. Rome Auditorium. SAIS

12:30

p.m.

“Sovereignty in the Arctic: Avoiding a New Geopolitical Conflict,” a SAIS Foreign Policy Institute debate with Ruth Wedgwood,

Tues., April 26, 4 p.m. The 2011 Annual Cecile Pickart Lecture— “Structural Insights Into Ubiquitin Signaling” by Cynthia Wolberger, SoM and Howard Hughes Medical Institute. Sponsored by Biochemistry and Molecular Biology. W1214 SPH. EB Tues., April 26, to Thurs., April 28. Fatalism in American Film Noir:

Some Cinematic Philosophy II, a Humanities Center lecture and discussion series by Robert Pippin, University of Chicago. 208 Gilman. HW •

Thurs.,

April

28,

p.m.

“Reporting on Global Health,”

Tues.,

April

26,

p.m.

“Sexual Agency in Fritz Lang’s Scarlet Street.”

•

Wed., April 27, 4 p.m. Discussion of Robert Aldrich’s Kiss Me Deadly.

•

Thurs., April 28, 4 p.m.

Wed., April 27, 6:30 p.m. “The

Thurs., April 28, 12:30 p.m.

26,

12:30

“Political Economy of the Financial Crisis in Central and Eastern Europe,” a SAIS European Studies Program/Center for Transatlantic Relations discussion with Mitchell Orenstein, SAIS. A reception follows. For information, email atobin1@jhu .edu or call 202-663-5796. 806 Rome Bldg. SAIS

Tues., April 26, 5 p.m.

p.m.

April

26,

SAIS

“Rainfall, Human Capital and Democracy,” a Bernard L. Schwartz Forum on Constructive Capitalism with Stephen Haber, Stanford University, and Helen Bing, Hoover Institution. For information email rbwashington@jhu.edu or call 202-663-5650. 806 Rome Bldg. SAIS Tues.,

April

Charles Doran, Kurt Volker and Charles Gati and Zbigniew Brzezinski (moderator), all of SAIS. (Event is open to the SAIS community only.) For information or to RSVP, email ckunkel@jhu .edu or call 202-663-5772. Kenney Auditorium, Nitze Bldg.

“Philosophy by Other Means I—After the Beautiful: Hegel and the Philosophy of Visual Modernism.”

Thurs., April 28, 12:15 p.m.

“The Rhodes Blood Libel (1840): The End of the Myth of Sephardi Superiority,” a Jewish Studies lecture by visiting professor Olga Borovaya, Russian State University for the Humanities. Smokler Center for Jewish Life (Hillel). HW Distinguished Lecture in Art of the Ancient Americas— Topics

in the Art of Ancient West Mexico with featured speaker Richard Townsend, The Art Institute of Chicago. Sponsored by History of Art and The Walters Art Museum. •

Thurs., April 28—

p.m. “Ancestors, Tomb Sculptures and Seasonal

7 p.m. Distinguished Lecture—“Approaching the Imagery of Ancient West Mexico.” Walters Art Museum Parlor, 5 West Mount Vernon Place.

•

Sat.,

April

30,

p.m.

“The Art and Archaeology of Ancient West Mexico,” a public lecture. Graham Auditorium, Walters Art Museum (enter on Centre Street)

Thurs., April 28, 4:30 p.m.

The Annual James W. Poultney Memorial Lecture—“Pindar and the Monuments” by Richard Neer, University of Chicago. Sponsored by Classics. 50 Gilman. HW Thurs., April 28, 5:15 p.m.

“Exhortation to Women: Lucrezia Marinella (1571?–1653),” a German and Romance Languages and Literatures lecture by Laura Benedetti, Georgetown University. 479 Gilman. HW The Elizabeth Ratner Memorial Lecture—“Suicide Risk Assessment in the ED: A Practical Guide for Emergency Physicians” by Robert Orman, Providence St. Vincent Medical Center. Co-sponsored by Emergency Medicine and Psychiatry and Behavioral Sciences. Owens Auditorium, CRB. EB

Fri., April 29, 11:30 a.m.

Mon., May 2, 8:30 a.m. The William M. Shelley Memorial Lecture—“Non-Alcoholic Fatty Liver Disease” by Linda Ferrell, University of California, San Francisco. Hurd Hall. EB

MUSIC

Wed., April 27, 8 p.m. The Peabody Concert Orchestra and Peabody Singers perform music by Schumann and Mozart. (See In Brief, p. 2.) $15 general admission, $10 for senior citizens and $5 for students with ID. Friedberg Hall. Peabody Thurs., April 28, and Fri., April 29, 7:30 p.m. “Ancient

Airs and Dances,” performance of early music by the Peabody Renaissance Ensemble. $15 general admission, $10 for senior citizens and $5 for students with ID. Griswold Hall. Peabody The Peabody Symphony Orchestra

Sat., April 30, 8 p.m.

Continued on page 13

Calendar Key APL BRB CRB EB HW JHOC

(Events are free and open to the public except where indicated.)

Applied Physics Laboratory Broadway Research Building Cancer Research Building East Baltimore Homewood Johns Hopkins Outpatient Center KSAS Krieger School of Arts and Sciences NEB New Engineering Building PCTB Preclinical Teaching Building SAIS School of Advanced International Studies SoM School of Medicine SoN School of Nursing SPH School of Public Health WBSB Wood Basic Science Building WSE Whiting School of Engineering