NEUROBIOLOGY WITH BIOMODULE
BIOLOGY THE SYSTEM FOR DEMONSTRATION OF THE NERVOUS SYSTEM IN BIOLOGY CLASSES
BIOMODULE System Components for Simulation Experiments
BIOMODULE - THE SYSTEM Use the BIOMODULE for representing processes on nerve cells and the the nervous system with simulation experiments.
to a supporting or inhibiting output on a downstream component depending on the result.
The BIOMODULE is modular designed i.e. every »module« of the nervous system relates to a module in the BIOMODULE System. Therefore teachers can select their experiment according to didactic perspectives and develop the experiments from the required system components.
The design for the separate experiment(s) is executed by simply connecting the required BIOMODULE components on the plug-in board; the functions of the nerve conductors (axons) is assumed via cables.
The BIOMODULE has been developed on the basis of the day-today requirements for teaching practices in close collaboration with teachers. All the sensory components, the synapse component and the stimulus component have a separate output for supporting and inhibiting stimuli with which the other components can be controlled. The information will be transmitted via stimuli to the downstream components. The nerve cell components integrate the incoming signals and form an output signal which, is transmited on
The power supply for the component is executed directly via a touch-safe, extra-low voltage of ±8 V from the plug-in board which is supplied from a power pack. All parts of the BIOMODULE system are protected against short-circuits and resistant to faulty switching. The simplified operating and the electrical safety from the BIOMODULE in combination with the multiple variable application possibilities enable the teacher to concentrate fully on the contentrelated aspects of their experiment.
BENEFITS MODULAR SYSTEM UNCOMPLICATED AND FLEXIBLE EXPERIMENTAL DESIGN FROM SIMPLE EXPERIMENTS UP TO COMPLEX SYSTEMS TRANSPARENT AND CLEARLY STRUCTURED
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GRAPHICAL REPRESENTATION OF THE SYSTEM MODULES OPTICAL AND ACOUSTIC REPRESENTATION OF THE SIGNALS TOUCH-SAFE, SIMPLIFIED OPERATING POWER SUPPLY
PRODUCT OVERVIEW BASIC EQUIPMENT
Plug-in board 90 x 60 cm
Power supply
STIMULUS MODULES
Light source module
SENSORY CELL MODULES
Stimulus source module
Synapse module
Light sensory cell module
Auditory cell module
Adaptive temperature sensory cell module
Tactile sensory cell module
NERVE CELL MODULES
Unineuron module
Demonstration neuron module
EFFECTOR ORGAN MODULES
Pupil module
Eyelid module
Drug function module
MEASURING MODULES
Muscle module
Gland module
Bioscale, green
Bioscale, red
Biocounter
Loudspeaker
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EXPERIMENTS BIOMODULE BASIC KIT 662 2201 Processes on nerve cells and in the nervous system will be represented with simulation experiments. The basic model enables 6 experiments to be executed on the basis of the Literature 668 78EN. Scope of delievery: 662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 203
2 x Connection cable (5 cm)
662 210
Light source module
662 212
Light sensory cell module
662 216
Demonstration neuron module
662 230
Loudspeaker
Cat. No.
Description
662 2201
BIOMODULE Basic Kit
DETECTION OF NERVE ACTIVITY
Additionally recommended 668 78EN
LIT: Experiments with BIOMODULE
STIMULUS REACTION DIAGRAM BD4.1.1.07 The correlation between the signal strength, stimulus transmission and reaction will be graphically clarified by utilising the effector organ module. The dependency of the pupil opening on the light signal will be comprehensively displayed here. Required devices and equipment:
THE PUPIL AND EYE LID OPENINGS ARE DEPENDENT ON THE AMBIENT BRIGHTNESS
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Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 210
Light source module
662 204
3 x Connection cable (12 cm)
662 212
Light sensory cell module
662 216
Demonstration neuron module
662 226
Pupil module
662 228
Eyelid module
668 78EN
LIT: Experiments with BIOMODULE
EXPERIMENTS PROCESSING STIMULI BD4.1.1.09 An explanation for the sensory and nerve cells as well as for transmitting the signals received will be explained on the BIOMODULE System. Along with the light sensitive cells as a basic element of every eye will be represented along with e.g. the mechanical deflection of tactile hairs as triggering signals. Required devices and equipment: Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 230
Loudspeaker
662 233
Biocounter
662 204
1 x Connection cable (12 cm)
662 205
1 x Connection cable (25 cm)
662 223
Tactile sensory cell module
668 78EN
LIT: Experiments with BIOMODULE
THE TACTILE HAIRS ARE STIMULATED VIA MECHANICAL DEFLECTION
CODING STIMULI BD4.1.1.13 The strength of the received stimulus must be coded for the signal transmission. This occurs via the frequency modulation from the action potential. The dependency of the frequency of the action potential on the stimulus strength can be displayed very legibly by utilising the stimulus input module and the downstream loudspeaker. Required devices and equipment:
DEPENDENCY OF THE ACTION POTENTIAL FREQUENCY ON THE STIMULUS STRENGTH
Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
Stimulus source module
662 231
Bioscale, green
662 230
Loudspeaker
662 233
Biocounter
662 204
2 x Connection cable (12 cm)
662 205
3 x Connection cable (25 cm)
662 216
Demonstration neuron module
662 212
Light sensory cell module
668 78EN
LIT: Experiments with BIOMODULE
5
EXPERIMENTS REPRESENTING ACTION POTENTIALS BD4.1.2.06 If the stimulus threshold is exceeded, then action potentials will occur which are essential for the nerve conduction. The Experiments with BIOMODULE will clarify the correlation between the stimulus strength, stimulus threshold and action potential. Required devices and equipment: Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
Stimulus source module
662 216
Demonstration neuron module
662 233
Biocounter
662 231
Bioscale, green
662 214
Gland module
662 205
1 x Connection cable (25 cm)
662 204
2 x Connection cable (12 cm)
662 203
1 x Connection cable (5 cm)
662 207
2 x Measuring electrode symbol
668 78EN
LIT: Experiments with BIOMODULE
DEMONSTRATION FOR THE ELECTRONIC PROPAGATION FROM VOLTAGE VARIATIONS ON THE MEMBRANE
TRANSMITTING STIMULI BD4.1.2.08 The basic principles for the stimulus transmission will be made comprehensible in additional experimental designs for nerve and sensory cells. Along with the saltatory stimulus conduction, the continuous stimulus conduction will also be identified and intuitively imparted via local verification of the nerve activity. Required devices and equipment:
PROPAGATION OF THE IMPULSE WITH NEURON MODULE
6
Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
Stimulus source module
662 231
Bioscale, green
662 233
Biocounter
662 204
2 x Connection cable (12 cm)
662 216
Demonstration neuron module
668 78EN
LIT: Experiments with BIOMODULE
EXPERIMENTS SUPPORTING AND INHIBITING STIMULI BD4.1.3.02 Not every impulse has a resulting effect on the signal transmission. The BIOMODULE enables various experimental designs for comprehensible representations for the different effects of supporting and inhibiting impulses. Required devices and equipment: Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
Stimulus source module
662 232
Bioscale, red
662 233
Biocounter
662 204
2 x Connection cable (12 cm)
662 205
2 x Connection cable (25 cm)
662 230
Loudspeaker
662 216
Demonstration neuron module
668 78EN
LIT: Experiments with BIOMODULE
THE INHIBITING POSTSYNAPTIC POTENTIAL (SP)
SUMMATING STIMULI BD4.1.3.03 Summation stimuli on various nerve sensory cells can convene on a synapse and influence them in various ways. To decide whether the threshold value for the action potential has been exceeded, there will be an of the excifactory and stimuli in the synapse. The principle can be competently clarified by utilising the sensory cell, synapse and neuron modules. Required devices and equipment:
STIMULUS SUMMATION IN SYNAPSE AND EXCEEDING THE THRESHOLD
Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
2 x Stimulus source module
662 230
Loudspeaker
662 233
Biocounter
662 204
3 x Connection cable (12 cm)
662 205
2 x Connection cable (25 cm)
662 231
Bioscale, green
662 216
Demonstration neuron module
668 78EN
LIT: Experiments with BIOMODULE
7
EXPERIMENTS STIMULUS THRESHOLD BD4.1.3.06C On the basis of the universal neuron, the principle for the stimulus threshold will be demonstrated on the BIOMODULE. Stimuli below thereshold do not result in stimulus transmission and/or conductivity. The lowest degree of stimulation, which is necessary for stimulus transmission, will be discernible. Thereby the principles for the stimulus summation and the changes in sensitivity for the neurons will also be comprehensible. Required devices and equipment: Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
3 x Stimulus source module
662 233
Biocounter
662 203
2 x Connection cable (5 cm)
662 204
2 x Connection cable (12 cm)
662 213
Unineuron module
662 217
Synapse module
668 78EN
LIT: Experiments with BIOMODULE
STIMULUS SUMMATION AND SENSITIVITY OF THE SYNAPSE
EFFECTS FROM NARCOTICS BD4.1.3.12 Toxicants and narcotics such as e.g. opium and clonidine have longterm effects on the stimulus transmission in the nervous system. Utilising the narcotics module enables an effective conveyance for the effects of these substances on the signal transmission. Required devices and equipment:
EFFECTS OF TOXICANTS ON THE SYNAPTIC SIGNAL TRANSMISSION
8
Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 211
Stimulus source module
662 230
Loudspeaker
662 203
1 x Connection cable (5 cm)
662 204
2 x Connection cable (12 cm)
662 205
1 x Connection cable (25 cm)
662 213
2 x Unineuron module
662 215
Drug function module
662 229
Muscle module
668 78EN
LIT: Experiments with BIOMODULE
EXPERIMENTS POSITIVE AND NEGATIVE FEEDBACK BD4.1.3.15 Positive feedback loops can enable a weak signal to be strengthened or to be extended. Negative feedbacks however create a weakening of a strong signal or will shorten it. Utilising the universal neuron module, incoming signals and the effector organ modules this principle is shown in a very descriptive and comprehensible representation. Required devices and equipment: Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 233
Biocounter
662 204
5 x Connection cable (12 cm)
662 217
Synapse module
662 213
2 x Unineuron module
662 229
Muscle module
668 78EN
LIT: Experiments with BIOMODULE
FEEDBACK SWITCHING WITH THE UNIVERSAL NEURON MODULE
LATERAL INHIBITION BD4.1.3.18 Utilising multiple universal neuron modules, which will be contacted by various stimuli or synapse, the BIOMODULE creates a clearly discernible simulation for the lateral inhibition. Required devices and equipment:
SIMULATION OF THE LATERAL INHIBITION
Cat. No.
Description
662 200
Plug-in board for BIOMODULE
662 201
Power supply for BIOMODULE
662 233
Biocounter
662 204
7 x Connection cable (12 cm)
662 205
1 x Connection cable (25 cm)
662 217
3 x Synapse module
662 213
3 x Unineuron module
668 78EN
LIT: Experiments with BIOMODULE
9
TEACHING CONTENT PROCESSING STIMULI STIMULUS REACTION DIAGRAM STIMULUS THRESHOLD TRANSMITTING STIMULI CODING STIMULI REPRESENTING ACTION POTENTIALS SUPPORTING AND INHIBITING STIMULI SUMMATING STIMULI LATERAL INHIBITION EFFECTS FROM NARCOTICS POSITIVE AND NEGATIVE FEEDBACK BIOLOGICAL REGULATING CIRCUIT
GERMANY: LD DIDACTIC GmbH Leyboldstr. 1 50354 Huerth, Germany Tel.: +49 2233 604 0 Fax: +49 2233 604 222 E‐Mail: info@ld‐didactic.de www.ld‐didactic.com
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Technical details subject to change without notice
110 0604EN 02.2016 LD
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