Global Medical Tourism Magazine - December 2023 by London Press House

International edition

Global Medical

Tourism Winter 2023

“One of the primary motivations for medical tourism is the potential cost savings”

How Might Healthcare Transform in the Next 50 Years?

AI prompts wave of medical tourism Dr. Raza Siddiqui Executive Director, RAK Hospital CEO, Arabian Healthcare Group

ETHICAL CONSIDERATIONS IN MEDICAL TOURISM 1

LOOK TOWARDS THE NEXT BIG OPPORTUNITY 2

Contents Impact of Preoperative Endovascular Embolization on Immediate Meningioma Resection Outcomes 06

Transforming Medical Tourism: The Intersection of Technology and Healthcare 18

Tau and Other Proteins Found in Alzheimer’s Disease Spinal Fluid are Linked to Retromer-Mediated Endosomal Traffic in Mice and Humans 08

Type 2 Diabetes 20

Understanding the Benefits and Risks of Medical Tourism 12

Impact of Preoperative Endovascular Embolization on Immediate Meningioma Resection Outcomes 26

Top Destinations for Medical Tourism and Their Specializations 14 Ethical Considerations in Medical Tourism 16

Afamelanotide: Promising Treatment for Erythropoietic Protoporphyria (EPP) 24

Nicotinamide Mononucleotide NMNas an Anti-Aging Health Product – Promises and Safety Concerns 28

Major Beauty Benefits of Apricot Oil 32 The Impact of Alzheimer’s Drug Donanemab: Promising Results 34 How Might Healthcare Transform in the Next 50 Years? 36 AI prompts wave of medical tourism 40 An Interview with Dr Ben Chan 44 Dr. Raza Siddiqui Executive Director, RAK Hospital CEO, Arabian Healthcare Group 46

Fertility tech in 2023: At-home, Personalisation and Accessibility 30 Contact us to find out more about exhibiting in the UAE

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Editor-in-Chief

Letter

Dr Azul Estefanía Torres Rivera azul.rivera@globalhealthv.com

Vice Assistant Editor Mr Stephen Mackins, Ph.D stephen.mackins@globalhealthv.com

From the Editor

Associate Editors Mrs Freya Jones Mr R.Singh BSc

Dear Readers, As you read these lines of the new edition

of humanity: fear, warmness, questions,

Co Editors

of Global Medical Tourism Magazine, we are

science, but above all “hope”; just makes you

Kavita Sharma

embarking on the last month of the year

feel a connection. Traveling to a different

2023, putting up Christmas lights and trees

country can be scary and challenging, this

MPharm, PG Cert Independent Prescriber, PG Cert in Diabetes Care, Advanced Diploma in Diet & Nutrition

to prepare for those warm moments by the

is why all of us at the enterprise of medical

Dr Simran Dhaliwal

end of the year.

tourism share an important task: making

M.D. BSc (Hons)

a patient feel at home while being on the And every new year has lots of promises

other side of the world.

Team Members

and best wishes, this will not be the

While reading the following pages, I invite

Dr Ben Chan MBBS (melb)

exception, while we are still recovering

you to explore, to imagine, to wonder; allow

Fellow of Australasian College of Aesthetic

from the pandemic that made us stop

yourselves to dream!

and reset and of many other impacting this new year feels renewed and filled

Dr Azul Estefanía Torres Rivera

with hope. I honestly just love when a leap

Editor-in-Chief

situations happening around the world,

Medicine and Cosmetic Physicians College of Australia Medical Director of Aesthetics and Skin Institute (USA/UK/Aust)

Dr Raza Siddiqui Group CEO Arabian Healthcare Group and Executive Director RAK Hospital

year comes, it feels special and as if luck has

First Indian Board Member – RAK Chamber of

come to our lives.

Commerce and Industry Board Member – RAK Hospital Board Member – Arabian Healthcare Group

After 12 years of dedication on medical

Board Member – RAK Medical and Health

tourism, I have been able to be part of a

Sciences University

quick evolving branch of medicine, every

Advisory Board Member – CEO Club International, Dubai

year our patients are changing and tourism

Advisory Board Member – Arab Health 2020 Advisory Board Member - Middle East Cities

medicine evolves with them, trying to

Center at the American University, Dubai.

keep the pace is stimulating and while

Board Member UNDRR

sometimes we may feel discouraged,

Redzheb Bayryamali

the reality is that there’s nothing more

BSc (Hons)

satisfactory than being able to help a new

John Emmerson

patient or couple. Being dedicated myself to

BA (Hons)

the Fertility industry, I can honestly say that there is no greater satisfaction than to see

parents hold their newborn baby.

info@globalhealthv.com +(44) 207 175 5240

Medical Tourism is a door of opportunities

167-169 Great Portland Street, 5th Floor,

for patients that have lost hope or that have

London, W1W 5PF, United Kingdom

run out of possibilities for their own health

For advertising and sales enquiries, email

journey; but as it evolves it has also become

sales@globalhealthv.com

a different way of traveling and exploring To feature in the next edition, email

new cities and cultures. Being able to tear

editor@globalhealthv.com

up the miles and discover that so many other places in the world have such different cultures, architecture, and histories; while still sharing emotions and characteristics

Design & Digital Partner:

Dr Azul Estefanía Torres Rivera

Gloss, hello@gloss.agency Publishing Partner:

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Impact of Preoperative Endovascular Embolization on Immediate Meningioma Resection Outcomes OBJECTIVE

RESULTS

Preoperative embolization of meningiomas

Overall, 27,008 admissions met the inclusion

can facilitate their resection when they

criteria, and 633 patients (2.34%) had

are difficult to remove. The optimal use

undergone preoperative embolization and

and timing of such a procedure remains

26,375 (97.66%) had not. The embolization

controversial given the risk of embolization-

group was younger (55.17 vs 57.69 years, p

linked morbidity in select clinical settings. In

< 0.001) with a lower proportion of females

this work, the authors used a large national

(63.5% vs 69.1%, p = 0.003), higher Charlson

database to study the impact of immediate

Comorbidity Index (p = 0.002), and higher

preoperative embolization on the immediate

disease severity (p < 0.001). Propensity

outcomes of meningioma resection.

score matching retained 413 embolization and 413 nonembolization patients. In the

METHODS

matched cohort, preoperative embolization

Meningioma patients who had undergone

was associated with increased rates of

elective resection were identified in the

cerebral edema (25.2% vs 17.7%, p = 0.009),

National (Nationwide) Inpatient Sample (NIS)

posthemorrhagic anemia or transfusion

for the period 2002–2014. Patients who had

(21.8% vs 13.8%, p = 0.003), and nonroutine

undergone preoperative embolization were

discharge (42.8% vs 35.7%, p = 0.039).

propensity score matched to those who had not, adjusting for patient and hospital characteristics. Associations between preoperative embolization and morbidity, mortality, and nonroutine discharge were investigated.

There was no difference in mortality (≤ 2.4% vs ≤ 2.4%, p = 0.82). Among the embolization patients, the mean interval from embolization to resection was 1.49 days. On multivariate analysis, a longer interval was significantly associated with

Reference Brandel MG;Rennert RC;Wali AR;Santiago-Dieppa DR;Steinberg JA;Lopez Ramos C;Abraham P;Pannell JS;Khalessi AA; (no date) Impact of preoperative endovascular embolization on immediate meningioma resection outcomes, Neurosurgical focus. Available at: https://pubmed.ncbi.nlm.nih. gov/29606044/ (Accessed: 20 December 2023).

nonroutine discharge (OR 1.33, p = 0.004) but not with complications or mortality.

CONCLUSIONS Relative to meningioma patients who do not undergo preoperative embolization in the same admission, those who do have higher rates of cerebral edema and nonroutine discharge but not higher rates of stroke or death. Thus, meningiomas requiring preoperative embolization represent a distinct clinical entity that requires prolonged, more complex care. Further, among embolization patients, the timing of resection did not affect the risk of inhospital complications, suggesting that the timing of surgery can be determined according to surgeon discretion.

Tau and other proteins found in Alzheimer’s disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans UNDERSTANDING TRAFFIC JAMS IN ALZHEIMER’S

amino terminus of the transmembrane

unknown. Recent genomic studies have

proteins APLP1 and CHL1, and the mid-

identified endosomal trafficking as a

Alzheimer’s disease (AD) is characterized

domain of tau, which is known to be

biological pathway pathogenic in AD,

by exaggerated protein accumulation

unconventionally secreted and elevated

and subsequent data have established

in the extracellular milieu in the brain.

in AD. In patients with AD dementia, the

that the defective pathway manifests as

The endosomal pathway is responsible

concentration of amino-terminal APLP1

endosomal traffic jams (6).

for the secretion of proteins after

and CHL1 in the CSF correlated with tau

cleavage, and defective endosomal

and phosphorylated tau. Similar results

pathway contributes to AD pathogenesis.

were observed in healthy controls, where

However, which proteins are affected

both proteins correlated with tau and

by defective endosomal pathway is still

phosphorylated tau and were elevated in

unclear. Now, Simoes et al. performed

about 70% of patients in the prodromal

proteomic analysis in CSF from mice

stages of AD. Collectively, the mouse-to-

with defective endosomal trafficking and

human studies suggest that retromer-

validated their findings in patients with

dependent endosomal trafficking can

AD and showed that APLP1 and CHL1

regulate tau, APLP1, and CHL1 CSF

expression were increased and correlated

concentration, informing on how AD’s

with tau expression. The results provide

trafficking pathway might contribute to

precious insight regarding the effect of

disease spread and how to identify its

endosomal trafficking alterations in AD.

trafficking impairments in vivo.

ABSTRACT

INTRODUCTION

Endosomal trafficking has emerged

The abnormal accumulation of

as a defective biological pathway in

extracellular proteins is a hallmark

Alzheimer’s disease (AD), and the

feature of Alzheimer’s disease (AD), as

pathway is a source of cerebrospinal

typified by the cleaved fragments of the

fluid (CSF) protein accumulation.

amyloid precursor protein (APP) and the

Nevertheless, the identity of the CSF

microtubule binding protein tau. APP

proteins that accumulate in the setting

is cleaved in the endosome (1, 2), and

of defects in AD’s endosomal trafficking

its fragments are secreted through the

pathway remains unknown. Here, we

endosomal pathway, representing an

performed a CSF proteomic screen in

example of so-called unconventional

mice with a neuronal-selective knockout

secretion. Although it is now understood

of the core of the retromer complex

that tau is unconventionally secreted

VPS35, a master conductor of endosomal

from neurons via direct translocation

traffic that has been implicated in

across the plasma membrane (3, 4), the

AD. We then validated three of the

mechanisms underlying active secretion

most relevant proteomic findings: the

of tau fragments (5) remain largely

Some of the best evidence in support of this conclusion is

Retromer-dependent endosomal trafficking has been linked to

provided by molecules related to retromer, a multimodular

many of AD’s core features (14)—including amyloid pathology

protein assembly that is considered the “master conductor”

(11, 14–17), tau pathology (18), glial pathology (19, 20), and the

of sorting and trafficking cargo out of the endosome (7).

enlargement of neuronal endosomes (15, 21–23).

For example, mutations in SORL1, encoding a key retromer receptor in the brain (1, 8), are causally pathogenic in AD (9, Reference Simoes S;Neufeld JL;Triana-Baltzer G;Moughadam S;Chen EI;Kothiya M;Qureshi YH;Patel V;Honig LS;Kolb H;Small SA; (no date) Tau and other proteins found in alzheimer’s disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans, Science translational medicine. Available at: https://pubmed. ncbi.nlm.nih.gov/33239387/ (Accessed: 20 December 2023).

10). In addition, the core retromer protein VPS35 is deficient in regionally vulnerable AD brains (11), and a rare de novo mutation in VPS35 has been identified in AD (12), as have variants in a range of other retromer-related genes (13).

Understanding the Benefits and Risks of Medical Tourism 12

INTRODUCTION:

without extensive delays, improving their

Medical tourism, the practice of travelling

quality of life and reducing potential

LEGAL AND ETHICAL DIFFERENCES:

abroad to receive medical treatment, has

health risks.

Different countries may have varying legal and ethical frameworks regarding

gained popularity in recent years. This article explores the benefits and risks

RISKS AND CONSIDERATIONS:

associated with medical tourism, helping

QUALITY AND SAFETY:

potential medical tourists make informed

Ensuring the quality and safety of

decisions.

medical facilities and healthcare providers in the destination country is

BENEFITS OF MEDICAL TOURISM:

crucial. Researching the accreditation,

COST SAVINGS:

certifications, and reputation of hospitals

One of the primary motivations for

and doctors is essential to minimize

medical tourism is the potential cost

potential risks.

medical treatments and patient rights. Understanding these differences and potential implications is crucial to protect the patient’s interests.

CONCLUSION: Medical tourism offers several benefits, including cost savings, access to specialized procedures, and reduced wait times. However, it is essential

savings. Many countries offer medical

COMMUNICATION AND LANGUAGE BARRIERS:

for individuals considering medical

Language differences and

weigh the associated risks. By making

accommodation expenses.

communication challenges can pose

informed decisions and taking necessary

obstacles in obtaining proper medical

precautions, patients can maximize

ACCESS TO SPECIALIZED PROCEDURES:

care and understanding treatment

the benefits of medical tourism while

options. It is important to consider

minimizing potential pitfalls.

Access to Specialized Procedures:

language support services or seek

Medical tourists often seek treatment

assistance from medical facilitators or

abroad to access specialized procedures

translators.

procedures at significantly lower costs compared to the patient’s home country, even when factoring in travel and

or technologies that may not be available in their home country. This includes

POST-TREATMENT CARE:

treatments such as stem cell therapy,

After undergoing a medical procedure

experimental procedures, or

abroad, patients may need ongoing care

cutting-edge surgeries.

or follow-up consultations. Planning for post-treatment care in the home

REDUCED WAIT TIMES:

country should be a part of the

In countries with long waiting lists for

overall decision-making process.

certain procedures, medical tourism can provide faster access to treatments. Patients can schedule their procedures

tourism to thoroughly research and

Reference Centers for Disease Control and Prevention. Blood clots and travel: what you need to know. Reviewed February 2021. Hurley R. China harvested organs from political prisoners on substantial scale, says tribunal. BMJ. 2018 Dec;363(1):5250. doi:10.1136/bmj.k5250 Ambagtsheer F, Van Balen L. I’m not Sherlock Holmes: suspicions, secrecy, and silence of transplant professionals in the human organ trade. Euro J Criminol. 2019 Jan;17(6):764-783. doi:10.1177/1477370818825331

Top Destinations for Medical Tourism and Their Specializations INTRODUCTION:

MALAYSIA:

Medical tourism involves traveling to specific

Malaysia has developed a robust healthcare

destinations to access healthcare services. This

system and attracts medical tourists with its

article highlights some of the top medical tourism

modern infrastructure, English-speaking medical

destinations and their specializations, helping

professionals, and competitive pricing. It is

potential medical tourists identify suitable locations

particularly known for medical specialties such

for their treatment needs.

as cardiology, orthopedics, oncology, and IVF treatments. The country’s capital, Kuala Lumpur, is a popular medical tourism hub.

THAILAND: Thailand has emerged as a leading destination for medical tourism. Renowned for its world-class

BRAZIL:

hospitals, affordable healthcare, and well-trained

Brazil is renowned for its expertise in cosmetic

medical professionals, it offers a wide range of

surgery, attracting patients from around the world.

procedures, including cosmetic surgery, dental

With a large number of board-certified plastic

treatments, fertility treatments, and elective

surgeons and state-of-the-art clinics, Brazil offers

surgeries.

a wide range of procedures, including breast augmentation, liposuction, and facelifts.

INDIA: India is a popular choice for medical tourists

CONCLUSION:

seeking a diverse range of treatments. The country

These destinations represent a fraction of the

is known for its highly skilled doctors, advanced

countries that cater to medical tourists. However,

medical infrastructure, and cost-effective healthcare

each destination has its own set of specialties, costs,

services. India excels in specialties such as cardiac

and healthcare standards. It is crucial for potential

surgeries, joint replacements, organ transplants, and

medical tourists to thoroughly research and choose

alternative medicine like Ayurveda.

a destination that aligns with their specific medical needs, budget, and desired quality of care.

MEXICO: Mexico attracts medical tourists primarily from the United States and Canada due to its proximity and affordable healthcare. The country offers various procedures, including cosmetic and dental surgeries, bariatric surgeries, and fertility treatments. Mexican cities like Tijuana and Cancun are known for their well-established medical facilities.

THAILAND

INDIA

MEXICO

MALAYSIA

BRAZIL

Ethical Considerations in Medical Tourism INTRODUCTION: Medical tourism raises various ethical concerns that need careful consideration. This article discusses some of the key ethical considerations associated with medical tourism, aiming to foster a deeper understanding of the complex ethical landscape surrounding this practice.

EQUITY IN ACCESS TO CARE: Medical tourism can exacerbate global

ETHICAL CONSIDERATIONS FOR LOCAL HEALTHCARE WORKERS:

health disparities by enabling individuals

Medical tourism can lead to brain drain

from high-income countries to access

in developing countries, as skilled

healthcare services that may be out of

healthcare workers may choose to work

reach for local populations in low-income

in the private medical tourism sector

countries. This raises questions about

rather than serving the local population.

the fair distribution of resources and the

This raises ethical questions about the

potential negative impact on the local

obligations of healthcare professionals

healthcare infrastructure.

towards their own communities and the potential negative impact on the local healthcare system.

INFORMED CONSENT: Obtaining informed consent can

CONCLUSION:

be challenging in medical tourism

Medical tourism presents complex

scenarios due to language barriers,

ethical considerations that require

cultural differences, and limited time

careful thought and analysis. Balancing

for consultation. It is crucial to ensure

the benefits to patients with the

that patients fully understand the

potential impact on local communities

risks, benefits, and alternatives of the

and healthcare systems is crucial. By

proposed treatments, as well as the

addressing these ethical concerns,

potential legal recourse in case of

stakeholders can work towards a more

adverse outcomes.

ethical and sustainable medical tourism industry that prioritizes patient well-

EXPLOITATION AND HUMAN TRAFFICKING:

being, equitable access to care, and

There have been instances where

respectful engagement with local

medical tourists have unknowingly

communities.

become victims of exploitation or human Reference Mogaka JJO, Mupara L, Tsoka-Gwegweni JM. Ethical issues associated with medical tourism in Africa. J Mark Access Health Policy. 2017 May 5;5(1):1309770. doi: 10.1080/20016689.2017.1309770. PMID: 28740618; PMCID: PMC5508395.

trafficking. It is important for patients to research and choose reputable medical facilitators and clinics to minimize the risks of falling prey to such unethical practices.

POST-TREATMENT FOLLOW-UP AND CONTINUITY OF CARE: After returning to their home country, medical tourists may face challenges in obtaining follow-up care or addressing complications that arise from their treatments abroad. Establishing protocols for post-treatment support and ensuring effective communication between healthcare providers in different countries are essential for maintaining continuity of care.

Transforming Medical Tourism: The Intersection of Technology and Healthcare INTRODUCTION:

information between healthcare

Medical tourism has witnessed a

providers, regardless of geographical

VIRTUAL REALITY (VR) AND AUGMENTED REALITY (AR):

remarkable transformation in recent

locations. In the context of medical

VR and AR technologies have found

years, thanks to advancements in

tourism, this allows for seamless

applications in medical tourism,

technology. This article explores the ways

continuity of care as patients can easily

revolutionizing patient education,

in which technology is revolutionizing

share their comprehensive medical

pre-operative planning, and

the field of medical tourism, improving

history with overseas healthcare

rehabilitation. Patients can virtually

patient experiences, expanding

facilities. Interoperable EHR systems

explore medical facilities, visualize

treatment options, and enhancing overall

enable physicians to access vital patient

treatment outcomes, and understand

healthcare outcomes.

information, including allergies, past

complex procedures in a more immersive

treatments, and diagnostic reports,

way. VR can also aid in post-operative

ensuring accurate diagnoses and

rehabilitation by providing interactive

personalized care.

exercises and simulations that enhance

TELEMEDICINE AND VIRTUAL CONSULTATIONS:

recovery and reduce complications.

Telemedicine has emerged as a game-changer in medical tourism.

ARTIFICIAL INTELLIGENCE (AI)

online platforms, patients can consult

HEALTH INFORMATION PORTALS AND MEDICAL TOURISM PLATFORMS:

with healthcare providers remotely,

Online platforms and health information portals cater specifically to medical

AI and ML algorithms are transforming

eliminating the need for physical travel. This enables individuals to access expert

tourists, providing a wealth of information

opinions, discuss treatment options,

about destinations, healthcare facilities,

and obtain second opinions from

doctors, and treatment options. These

renowned specialists around the world.

platforms enable patients to compare

Telemedicine also facilitates pre-travel

costs, read reviews, and make informed

consultations, ensuring patients are

decisions. They also offer features such

well-informed and prepared for their

as appointment scheduling, travel

medical journey.

arrangements, and post-treatment

Through video conferencing and

support, streamlining the entire medical

ELECTRONIC HEALTH RECORDS (EHRS) AND INTEROPERABILITY:

tourism process and enhancing patient convenience.

AND MACHINE LEARNING (ML): medical tourism by revolutionizing diagnostics, treatment planning, and patient care. AI-powered tools can analyze medical images, such as X-rays and MRIs, to detect abnormalities, assist in diagnosis, and predict treatment outcomes. ML algorithms can help personalize treatment plans based on patient data, optimizing efficacy and minimizing risks. Furthermore, AI chatbots can provide 24/7 support, answering patient queries and guiding

The digitization of health records has

them through the medical tourism

simplified the exchange of medical

process.

ROBOTIC SURGERY AND MINIMALLY INVASIVE TECHNIQUES: Robotic surgery has gained traction in medical tourism destinations, offering precise, minimally invasive procedures with reduced risks and faster recovery times. Robotic systems enable surgeons to perform complex surgeries with enhanced precision, dexterity, and visualization. Medical tourists can benefit from these advanced techniques, which often result in shorter hospital stays, fewer complications, and improved surgical outcomes.

DATA ANALYTICS AND PREDICTIVE MODELING: Big data analytics and predictive modeling are revolutionizing healthcare

CONCLUSION: Technology has become an integral part of the medical tourism landscape, shaping the way patients access healthcare services, receive treatments, and interact with healthcare providers. From telemedicine and EHRs to VR and AI, these advancements have improved patient experiences, expanded treatment options, and enhanced healthcare outcomes.

Reference Mohd Javaid, Abid Haleem, Virtual reality applications toward medical field, Clinical Epidemiology and Global Health, Volume 8, Issue 2,2020, Pages 600-605, ISSN 2213-3984 S. Bouchard, S. Dumoulin, G. Robillard, et al. Virtual reality compared with exposure in the treatment of social anxiety disorder: a three-arm randomised controlled trial Br J Psychiatry, 210 (4) (2017), pp. 276-283

by leveraging vast amounts of patient data to identify trends, predict disease patterns, and optimize treatment protocols. In the context of medical tourism, these technologies can assist in assessing patient suitability for specific treatments, analyzing risks, and providing personalized recommendations. Predictive modeling can also aid in forecasting medical tourism trends, helping healthcare providers and policymakers make informed decisions.

Type 2 Diabetes By Kavita Sharma MPharm, PG Cert Independent Prescriber, PG Cert in Diabetes Care, Advanced Diploma in Diet & Nutrition

Type 2 Diabetes–a condition often linked to poor diet and lifestyle choices. There has been a staggering rise in Diabetes from 108 million people in 1980 to a huge 422 million people in 2014 (WHO), the current figure of patients with Diabetes today is estimated to be even higher than previous figures. What was once usually diagnosed in patients that were middle-aged, we are now beginning to see more in younger patients in their 20s and even children. Having Type 2 Diabetes comes with its risk of complications especially if glucose levels remain uncontrolled. The complications usually develop 10-20 years after an initial diagnosis. So how does the future look for a child that is diagnosed with Type 2 Diabetes? Complications of Diabetic retinopathy in their 20s? Kidney disease followed by a high risk of a heart attack in their 30s? Is this the future we want for the next generation?

The NHS is spending a staggering 10%

they understand. When it comes to an

In addition to this South Asian women

of its budget treating Diabetes (90% of

initial diagnosis of Type 2 Diabetes I am

are less likely to exercise often due to not

these patients are Type 2 Diabetics. That’s

a firm believer in what caused it could

knowing how to or simply not feeling

a huge £9 billion spent on a condition

cure it – if poor diet and lifestyle choices

comfortable in front of others. A report

that is often preventable. This spending

caused it then a better diet and an active

carried out by Sporting Equals found 74%

is predicted to rise to £16.9 billion in

lifestyle could cure it. This is the basis

of South Asian women are undertaking

2035. If with all the modern advances

of the education that I am providing

less than 30 minutes of physical activity

in healthcare and medical technology,

in my diet and exercise classes. South

a week, this is what led me to create a

we still can’t reduce the prevalence and

Asians are 6 times more likely to develop

women’s only class so that these women

cost of Type 2 Diabetes treatment then

Diabetes than other populations and

can feel more comfortable in their

surely we need to rethink our approach to

there just isn’t enough accessible dietary

environment whilst attending these

treatment and prevention.

information available to them.

classes.

I have worked in a GP surgery for over 5

Going back to basics and educating

I am currently providing diet and exercise

years as a Clinical Pharmacist specialising

patients on the different food groups

classes hosted in Punjabi for South Asian

in Type 2 Diabetes and during this time

and the effect they have on our body,

patients in the West Midlands as well as

I have developed an interest in diet and

discussing healthy swaps, and how to

a 12-week weight management service

nutrition and exercise. Whilst training

continue eating South Asian foods in

with individualised diet plans. In addition,

and shadowing healthcare professionals

a healthier manner is where our focus

I am providing in-house diet, lifestyle and

during their Diabetes consultations I

needs to be. We shouldn’t be asking

Diabetes advice within GP surgeries for

soon realised a 10-minute consultation

these patients to stop eating the

their patients.

simply wasn’t enough for patients to fully

foods they only know how to cook but

understand Diabetes.

educating them on how to make these

For more information please visit

meals with ingredients and methods

desidiabetes.co.uk or Instagram page:

The education was even worse for South

healthier for them. There are many diets

@desidiabetes

Asian patients due to language barriers

plans out there from low-calorie meal

and there not being enough educational

replacements to no carbohydrate diets,

material in their languages. They are

but what happens once these diets come

often referred on to Diabetes educational

to their 3-month end?

courses which are often only in English and focussed on western diets. These

What has the person learned about the

patients glucose levels continued to

dietary choices they are going to make

deteriorate resulting in medication being

going forward? This is why the approach

increased almost after each blood test,

to preventing Type 2 Diabetes and its

but eventually, the medication will stop

complications needs to be focused on

being effective at which point Insulin is

diet education that is tailored to each

initiated. This is what made me realize

culture’s specific needs, we need a shift

that we cannot expect someone to

in how healthcare is presented to these

control their Diabetes if they do not

patients so that we can empower them

understand their condition.

to make educated decisions on their lifestyle and dietary habits, not just for

These patients were failing to link their

their future but also for the future of their

poor diet and lifestyle choices to their

families. This is the basis of the classes

increasing glucose levels. This is what

I host as well as the one-to-one weight

led me to create Desi Diabetes – to help

management plans I provide.

educate South Asians about Diabetes in a language and terminology that

INTRODUCTION: Erythropoietic Protoporphyria (EPP) Erythropoietic Protoporphyria (EPP) is a genetic condition characterised by a disturbance in heme biosynthesis, leading to an accumulation

Afamelanotide: Promising Treatment for Erythropoietic Protoporphyria (EPP)

of protoporphyrins in red blood cells (RBC). Individuals with

By Dr Simran Dhaliwal

hormone analogue, in EPP patients.

EPP experience acute pain upon exposure to light, and chronic exposure to the sun can result in skin thickening and wax-like scarring on the face. The activation of protoporphyrins upon light exposure leads to oxidative damage and inflammation on the skin. This article discusses a study evaluating the potential benefits of Afamelanotide, an alpha melanocyte stimulating

AFAMELANOTIDE AND ITS PROPERTIES

have more sun exposure. However, the

Additionally, exploring the mechanism

duration varied across different months.

of action of Afamelanotide, potential

Afamelanotide is a potent analogue of

Significantly, the QoL of EPP patients

combination therapies, its effectiveness

alpha melanocyte stimulating hormone.

increased by 14.01% after receiving

in other genetic conditions, and

It increases the production of eumelanin,

Afamelanotide treatment, indicating

application in various therapeutic areas

a type of pigment that provides

a positive impact on their overall

are worthy of investigation.

protection against the harmful effects

well-being. The size of the treatment

of ultraviolet (UV) radiation. In addition,

effect was found to increase with age.

CONCLUSION

Afamelanotide possesses antioxidant

Furthermore, QoL scores were lower on

The study highlights the efficacy of

and anti-inflammatory properties, which

high-intensity light days, while women

Afamelanotide in reducing pain and

may further contribute to its potential

generally reported higher pain scores,

phototoxicity symptoms, improving

therapeutic effects.

potentially due to biological, societal,

QoL, and increasing sunlight exposure

and cultural factors. Increasing age

tolerance in EPP patients. However,

was associated with lower pain scores.

further research with larger sample sizes

Adverse events were reported in 104

and longer follow-up periods is necessary

patients, with the most common being

to validate these findings and elucidate

nausea and flushing. Ineffectiveness of

the long-term safety and effectiveness

the implant was reported 38 times, but

of Afamelanotide. The study opens up

the association between the implant and

promising avenues for future research

outcomes lasted less than 60 days. The

and advancements in the treatment of

overall safety profile of Afamelanotide

EPP and other related conditions.

PURPOSE AND METHODOLOGY OF THE STUDY The primary objective of the study was to assess the association between Afamelanotide treatment and improved outcomes in EPP patients, particularly focusing on real-world experiences such as Quality of Life (QoL). The study employed a prospective postauthorisation safety and efficacy cohort design. The inclusion criteria consisted

was considered acceptable in routine clinical practice.

of adults with a confirmed diagnosis of

DISCUSSION AND FUTURE RESEARCH

EPP attending an outpatient clinic in the

The study’s findings demonstrate a

Netherlands. The sample size included 117

significant increase in QoL and time

participants who received Afamelanotide

spent outside for EPP patients receiving

through subcutaneous implants at a

Afamelanotide treatment. Although

dosage of 16mg, with a 60-day interval

the number of phototoxic reactions

and a total of four implants per year.

increased during treatment, a negative association was observed between the

Data collection occurred between June

duration of treatment and the number

2016 and September 2018, and included

of reactions. This suggests that longer

demographic features, dermatological

treatment duration led to fewer

screenings, routine laboratory tests,

phototoxic reactions, indicating the

adverse event assessments, diaries,

potential of Afamelanotide to mitigate

and questionnaires regarding QoL and

symptoms associated with light

light exposure. Outcome measures

exposure. The study also identified

encompassed the time spent outside,

a positive association between light

QoL scores, duration of phototoxic

intensity and the number of phototoxic

reactions, and protective clothing scores.

reactions, suggesting that higher light intensity outside resulted in a smaller

KEY FINDINGS

increase in reactions. Minor and self-

The study revealed promising results

limiting adverse events were reported

regarding the efficacy and safety

during the study, further supporting the

of Afamelanotide treatment in EPP

overall safety of Afamelanotide.

patients. Of the 117 patients who initiated

Future research avenues may include

the treatment, 115 (98%) continued it,

investigating the potential benefits of

indicating a high level of treatment

Afamelanotide in other dermatological

adherence. The duration of time spent

conditions such as vitiligo, actinic

outside increased per week, indicating

keratosis, solar urticaria, and post-

that the treatment enabled patients to

inflammatory hypopigmentation

References: Wensink, D. et al. (2020) “Association of afamelanotide with improved outcomes in patients with erythropoietic protoporphyria in clinical practice,” JAMA dermatology (Chicago, Ill.), 156(5), pp. 570–575. doi: 10.1001/jamadermatol.2020.0352

Impact of preoperative endovascular embolization on immediate meningioma resection outcomes 26

INTRODUCTION

investigated the associations between

does not impact the risk of in-hospital

Meningiomas, benign tumours that

preoperative embolization and various

complications. These insights contribute

develop in the meninges of the brain

outcomes, including morbidity, mortality,

to the ongoing discussion on the

and spinal cord, can pose challenges

and nonroutine discharge.

utilisation and timing of preoperative embolization in meningioma resection.

during surgical removal. Preoperative embolization has emerged as a potential

RESULTS

technique to facilitate the resection of

Among 27,008 admissions that met the

difficult-to-remove meningiomas.

inclusion criteria, 633 patients (2.34%) underwent preoperative embolization,

However, the optimal use and timing

while 26,375 (97.66%) did not. The

of this procedure remain subjects of

embolization group was characterised by

debate due to concerns about associated

younger age, lower proportion of females,

morbidity. In this study, the authors utilise

higher Charlson Comorbidity Index, and

a large national database to examine

higher disease severity.

the effects of immediate preoperative embolization on the immediate

After propensity score matching, a

outcomes of meningioma resection.

cohort of 413 embolization patients and 413 non embolization patients was

By investigating the impact of

analysed. The matched cohort revealed

embolization on morbidity, mortality,

that preoperative embolization was

and nonroutine discharge, the study

associated with higher rates of cerebral

aims to provide valuable insights into

edema, posthemorrhagic anaemia or

the role and risks associated with this

transfusion, and nonroutine discharge.

intervention.

However, there was no significant difference in mortality between the two

OBJECTIVES

groups. Among embolization patients,

Preoperative embolization of

the timing of resection did not impact

meningiomas can facilitate their

the risk of in-hospital complications,

resection when they are difficult to

suggesting that surgical timing can be

remove. The optimal use and timing of

determined based on surgeon discretion.

such a procedure remains controversial given the risk of embolization-linked

CONCLUSIONS

morbidity in select clinical settings.

The study findings indicate that

In this work, the authors used a large

meningioma patients who undergo

national database to study the impact of

preoperative embolization exhibit higher

immediate preoperative embolization on

rates of cerebral edema and nonroutine

the immediate outcomes of meningioma

discharge compared to those who do not

resection.

undergo embolization during the same admission.

METHODS The researchers identified meningioma

However, the rates of stroke and death

patients who underwent elective

did not differ significantly. These results

resection by analysing the National

suggest that meningiomas requiring

(Nationwide) Inpatient Sample (NIS)

preoperative embolization represent a

spanning from 2002 to 2014. Patients who

distinct clinical entity that necessitates

underwent preoperative embolization

prolonged and more complex care.

were then matched using propensity

Furthermore, the study suggests that

scores to those who did not undergo the

the timing of surgery in embolization

procedure, taking into account patient

patients can be determined according

and hospital characteristics. The study

to the surgeon’s judgement, as it

References: Brandel, M.G., Rennert, R.C., Wali, A.R., SantiagoDieppa, D.R., Steinberg, J.A., Ramos, C.L., Abraham, P., Pannell, J.S. and Khalessi, A.A., 2018. Impact of preoperative endovascular embolization on immediate meningioma resection outcomes. Neurosurgical Focus, 44(4), p.E6.

Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns HIGHLIGHTS

nicotinamide adenine dinucleotide

(NMN), which has shown promise as

•

Provides an overview of

(NAD+) in the body decline. This decline

an anti-aging agent. NMN increases

promises and safety concerns of

is associated with reduced energy

nicotinamide adenine dinucleotide

NMN as an anti-aging product.

production in mitochondria, increased

(NAD+) levels in the body, reversing

oxidative stress, DNA damage, cognitive

mitochondrial decay associated with

decline, and inflammatory conditions.

aging. It can be obtained through dietary

However, the precursor of NAD+, called

supplements and naturally occurs in

NMN, shows promise in slowing down

various plant and animal food sources.

this process by increasing NAD+ levels

Additionally, studies have explored

in the body. Several in vivo studies have

biotechnological production and

demonstrated positive therapeutic

purification of NMN from bacteria and

effects of NMN supplementation on

yeast.

•

Shows that NMN’s beneficial effects supported by in vivo studies.

•

Reveals that there is a lack of NMN’s clinical safety and efficacy studies

•

Suggests that proper clinical investigations are urgently

age-related complications. To address

needed on the effectiveness and

safety concerns, one preclinical study and

Apart from its anti-aging potential,

safety of NMN supplementation

one clinical study have investigated the

NMN has demonstrated a range

administration of NMN, and additional

of pharmacological activities in

INTRODUCTION

human clinical trials are currently

in vivo studies. Its connection to

The global elderly population has

underway. Given the abundance of

Alzheimer’s disease, obesity and related

been steadily increasing, leading to a

NMN-based anti-aging products in the

complications, cerebral and cardiac

growing demand for health products

market, it is crucial to conduct thorough

ischemia, and age- and diet-induced

aimed at promoting longevity and

clinical investigations to determine

type 2 diabetes has been extensively

mitigating age-related issues. Within

the effectiveness and safety of NMN

investigated. Increasing NAD+ levels

the realm of anti-aging health products,

supplementation.

in the body, particularly for anti-aging purposes, has garnered significant

nicotinamide mononucleotide (NMN) has garnered significant attention from both

Age management practices have led to a

attention, leading to studies involving

consumers and the scientific community.

surge in the global market for anti-aging

cell cultures, animal models, and human

This article intends to provide an

health products. However, many of these

clinical trials. This review aims to provide

overview on the current knowledge on

products are released without sufficient

up-to-date information on the promises

promises and safety concerns of NMN as

safety testing, driven by consumer

and safety concerns of NMN as an anti-

an anti-aging health product.

demand and high profit margins. It is

aging health product, as well as its other

crucial to conduct comprehensive

therapeutic uses and mechanisms of

scientific investigations, both preclinical

action, in order to stimulate further

and clinical, to ensure the safety and

research and explore its potential in

effectiveness of these products.

treating aging and age-related diseases.

SCIENTIFIC CONCEPTS UNDER REVIEW:

One such product gaining attention

Aging is characterized by reduced energy

As individuals age, the levels of

is nicotinamide mononucleotide

production in various organs, such as

the brain, adipose tissue, skin, liver,

human studies, NMN anti-aging products

skeletal muscle, and pancreas, due to the

are already available in the market,

depletion of NAD+. The decline in NAD+

with manufacturers promoting them

levels is caused by increased activity of

based on in vitro and animal research.

NAD+-consuming enzymes with age.

It is crucial to prioritize establishing the

These enzymes include NADase (CD38/

toxicology, pharmacology, and safety

CD157), poly (ADP-ribose) polymerase

profiles of NMN in humans, both in

(PARP), NAD+-dependent acetylase

healthy individuals and those with

(sirtuins), BST, and tankyrase (TNKS).

medical conditions. To determine NMN’s

Sirtuins utilize NAD+ for various functions

anti-aging efficacy, long-term follow-up

related to longevity, aging, and age-

studies on regular NMN consumers could

related physiological changes. CD38

provide valuable data. Manufacturers of

utilizes NAD+ to produce cyclic ADP-

NMN products should take responsibility

ribose and nicotinamide, while PARP

for conducting efficacy studies to

uses NAD+ for DNA repair by forming

support their claims.

branched ADP-ribose polymers. Administration of NMN can compensate for the depleted NAD+ levels caused by these NAD+-consuming enzymes, as NMN serves as an intermediate compound in NAD+ biosynthesis.

References: Yu, J., Laybutt, D.R., Kim, L.J., Quek, L.E., Wu, L.E., Morris, M.J. and Youngson, N.A., 2021. Exerciseinduced benefits on glucose handling in a model of diet-induced obesity are reduced by concurrent nicotinamide mononucleotide. American Journal of Physiology-Endocrinology and Metabolism, 321(1), pp.E176-E189.

CONCLUSIONS NMN, as a precursor and intermediate of NAD+ biosynthesis, shows potential in reversing age-related complications and slowing down the aging process by increasing NAD+ levels. While numerous studies have explored NMN’s anti-aging effects in cells and animal models, there is limited research on its long-term safety and clinical efficacy in humans. Only a few preclinical and clinical studies have investigated the safety of long-term NMN administration, and ongoing human clinical trials are yet to yield results. Despite the lack of comprehensive

Fertility tech in 2023: At-home, personalisation and accessibility By Natasha Spencer-Jolliffe

INTRODUCTION

revolutionise the field of fertility by

fertility treatment. He highlights that

Since the birth of the first baby

addressing these needs.

frequent clinic visits, invasive tests, and communication issues with clinic staff

conceived through in vitro fertilisation (IVF) in 1978, over 8 million individuals worldwide have been born using this technology. Although the success rates of IVF have improved since its inception, it is important to note that currently, only approximately one-third of patients undergoing IVF achieve a successful live birth. Paxton MaederYork, CEO and Founder of Alife Health, highlights the challenges associated with assisted reproduction from the patient’s perspective. These challenges include the high cost, the need for multiple attempts, the physical and emotional toll, and the lack of insurance coverage for these procedures. Equitable access and affordability are significant barriers to receiving fertility treatments such as IVF. In the United States, it has been reported that only one in twenty-five couples has access to the necessary fertility care. The high cost of an average IVF cycle, ranging from $15,000 to $30,000, further restricts the number of individuals who can afford quality care. These financial constraints contribute to limited access and disproportionately affect individuals seeking fertility treatments. Meir Olcha, a fertility specialist, Mira medical advisor, and medical director at Sama Fertility, emphasises the desire for fertility treatments to be accessible, affordable, effective, and less stressful for individuals seeking them. He believes that technology has the potential to

TRANSFORMING FERTILITY CARE: HARNESSING TECHNOLOGY FOR ACCESSIBLE, AFFORDABLE, AND EFFECTIVE SOLUTIONS In the clinical environment, research and development (R&D) in women’s health and infertility have historically been underfunded. Private-sector fertility clinics have largely driven recent advances. However, the field is now attracting more attention from investors and technology innovators, many of

during treatment are major stressors for patients. Recognizing and alleviating these stressors can significantly contribute to patient persistence until a successful outcome is achieved. Ensuring a positive patient experience throughout the treatment journey is essential for patient retention and ultimately reaching a successful outcome.

whom have personal motivations. Gary Nakhuda, co-founder of Olive Fertility Center in Canada, acknowledges that despite remarkable progress in assisted reproduction, outcomes remain disappointingly suboptimal. As a result, there is a persistent demand for the latest innovations that can offer even marginal improvements in success rates.Beyond the desired outcome of improved success rates, a key focus in fertility treatment is enhancing the overall patient experience. Fertility clinics encounter significant challenges in delivering the best possible care in this regard. The attainment of successful pregnancies through in vitro fertilisation (IVF) depends on a multitude of complex clinical decisions made by physicians. These decisions aim to provide optimal care tailored to the specific needs and circumstances of each patient. According to Gary Nakhuda, addressing the operational aspects of delivering care is crucial in reducing patient dropout and maintaining engagement with

ADVANCEMENTS IN FERTILITY TOOLS: TRANSFORMING REPRODUCTIVE MEDICINE Maeder-York asserts that the advancement of new technologies holds immense potential in advancing clinical care and enhancing the efficiency of clinic operations, ultimately benefiting a greater number of patients in achieving favourable outcomes. According to Maeder-York, the current landscape lacks a cohesive technology platform dedicated to empowering healthcare professionals in optimising their decisionmaking processes and enhancing the overall patient experience. The latest advancements in fertility health technology focus on digitising clinical data and workflows. Electronic

witnessing systems, robotic

experience. Real-time data collection

cryopreservation systems, and AI-led

and AI analysis help clinics derive

tools are improving reproductive health

actionable insights. Machine learning

outcomes. These technologies ensure

models optimise hormone selection,

accurate tracking of reproductive

while embryo image capture systems

materials, enhance cryopreservation

streamline grading processes and

processes, and utilise AI to analyse

integrate with EMR systems.

patient data for personalised treatments.

ADVANCING FERTILITY HEALTH: PIONEERING NEW FRONTIERS

Maeder-York emphasises that the

Digital-first care delivery is reshaping

current wave of sophisticated tools

fertility care, combining brick-and-mortar

builds upon the progress made in the

facilities with innovative platforms for

past decade across three significant

remote testing and monitoring. Alife

areas: embryology laboratory, at-home

Health’s AI-led tools optimise the IVF

testing and monitoring, and AI. The

process, reduce costs, and enhance

post-pandemic era has expanded

access. Mira’s at-home device enables

opportunities as telehealth and

hormone monitoring in urine, replacing

virtual care gain traction, alongside

invasive blood tests. Collaborations

an accelerated trend towards

between fertility tech and clinics

at-home testing.

improve outcomes and accessibility. The convergence of digital technology and

According to Maeder-York, these

remote monitoring is revolutionising

advancements share a common goal

fertility health.

of enhancing the quality of care and improving clinic efficiencies through the utilisation of data and software

SHAPING THE FUTURE OF FERTILITY TREATMENT

technology.

AI technology holds diverse applications

ADVANCEMENTS IN IVF TECHNOLOGY: AI, PERSONALISATION, AND STREAMLINED PROCESSES

predicting embryo quality. Automation

AI-driven analytics hold promise for

patient access. Personalised fertility

improving IVF outcomes, reducing costs, and enhancing transparency, according to Maeder-York. Despite challenges posed by age and biology, early testing like AMH can inform reproductive decisions. Sophisticated technologies offer a patient-centric approach and

in fertility, from treatment selection to in the laboratory and at-home testing innovations are on the horizon, optimising outcomes and improving care based on genomics is a significant breakthrough, while fertility preservation strategies gain attention. Ensuring the accuracy and validation of new technologies remains a priority in advancing fertility treatment.

collaboration, improving the IVF

Major Beauty Benefits of Apricot Oil UNVEILING THE SKIN-BENEFICIAL QUALITIES OF APRICOT OIL.

them down and release the enclosed fatty kernels. These kernels are then cold-

emollient properties, apricot oil

Apricot oil, also known as apricot kernel

pressed, and in some cases, pulverised

closely resembles the skin’s natural

oil, is derived from the fatty kernels

into a spongy paste. The crude oil is

sebum, making it an effective

found within apricot fruits. This versatile

further refined to remove any volatile or

moisturiser. It helps keep the skin

carrier oil possesses a delightful aroma

toxic components, ensuring a safe and

lubricated, provides a protective

and finds extensive use in skincare and

pure end product. Apricot oil ranks low

barrier, and can be used as a spot

body care formulations. Discovering

on the comedogenic scale, with a rating

treatment for dry patches.

the benefits of apricot oil can enhance

of “2”. While it may cause reactions in

your understanding of valuable skincare

individuals with extremely sensitive skin,

ingredients.

it generally does not clog pores. It serves

oil extends its benefits to the

Moisturising Benefits: With its

Hair and Scalp Health: Apricot

as an excellent alternative for those with

hair and scalp. When applied to

Apricots have been treasured for their

nut allergies who seek other carrier

the scalp, it can stimulate hair

gentle sweetness, velvety texture, and

oils, such as sweet almond oil. Rich in

follicles, promoting hair growth

their versatility in culinary applications.

essential fatty acids like oleic acid, linoleic

and strengthening weak or brittle

While the exact origins of apricot trees

acid, alpha-linolenic acid, palmitic acid,

strands.

remain uncertain, they are widely

and stearic acid, apricot oil nourishes

believed to have originated in China.

the skin. It is also abundant in vitamins

Incorporating apricot oil into your

In fact, it is said that the renowned

A and E, which further contribute to

skincare routine can help combat signs of

Chinese scholar Confucius conducted

its beneficial properties. With a better

ageing, soothe inflammation, moisturise

his teachings under the shade of a grand

understanding of its production and

the skin, and promote healthier hair and

apricot tree during the 6th century BCE.

composition, let’s explore how apricot oil

scalp.

can enhance your skin care routine. Apricot fruit and its oil have held a significant presence in various civilizations, often symbolising fertility and rejuvenation. This association may stem from the abundance of vitamins

UNLOCKING THE SKINNOURISHING POWERS OF APRICOT OIL

remarkable benefits for the skin.

APRICOT OIL OFFERS SEVERAL NOTEWORTHY BENEFITS FOR SKIN, INCLUDING:

Before delving into the specific

and nutrients present in apricots, offering

Anti-Aging Effects: High levels of

properties, let’s explore how apricot oil

vitamin A in apricot oil, known as

is sourced and what distinguishes this

retinol, aid in rebuilding collagen,

nourishing elixir as an excellent choice for

tightening the skin, and combating

skincare.

free radicals. Continuous use of retinol can help reduce fine lines and wrinkles.

THE SOURCING OF APRICOT OIL: NATURE’S NURTURING ELIXIR Apricot trees thrive in climates

Anti-Inflammatory Properties:

characterised by warm, dry summers

The omega-3 fatty acids, specifically

and mild winters. Consequently, major

alpha-linolenic acid, present in

apricot-growing regions include the

apricot oil contribute to its

Mediterranean, Australia, South Africa,

anti-inflammatory properties.

and parts of the North American west

This makes it beneficial for

coast. To extract apricot oil, the fatty pits

addressing skin conditions such as

of the fruit undergo a process that begins

eczema, psoriasis, and acne.

with soaking them in water to break

HARNESSING THE BENEFITS: INCORPORATING APRICOT OIL INTO YOUR SKIN CARE ROUTINE

Apricot Oil Face Mask:

Incorporating apricot oil into your skincare routine is a simple

•

and effective way to reap its benefits. Here are two ways to use

Combine 2 tablespoons of apricot oil, 1 teaspoon of matcha powder, and 1 tablespoon of agave nectar in a small bowl.

apricot oil in your skincare regimen: • Apricot Oil Dandruff Mask: •

Apply the mask to lightly dampened skin, gently massaging it in.

Mix 2 tablespoons of apricot oil, 1 tablespoon of lemon juice,

•

Leave the mask on for 10-15 minutes.

•

Rinse off with lukewarm water and follow up with toner

and 10 drops of tea tree oil in a medium bowl.

and the rest of your skincare routine. •

Apply the mask to damp or wet hair, focusing on the scalp.

These DIY masks allow you to enjoy the nourishing properties of apricot oil while addressing specific concerns like dandruff

•

Wrap your hair in a towel and leave the mask on

or giving your skin a revitalising boost. Remember to perform a

for at least 25 minutes.

patch test before applying any new ingredients to your skin to ensure compatibility and discontinue use if any irritation occurs.

•

Rinse thoroughly, and if needed, wash again and follow up with conditioner.

References: Apricot kernel oil - a light & quick-absorbing oil - skin & hair care (no date) Apricot Kernel Oil - A Light & Quick-Absorbing Oil - Skin & Hair Care. Available at: https://www.newdirectionsaromatics.com/blog/products/all-about-apricot-kernel-carrier-oils.html#:~:text=Used%20topically%2C%20Apricot%20Kernel%20Oil,%2C%20 fine%20lines%2C%20and%20puffiness. (Accessed: 22 September 2023).

The Impact of Alzheimer’s Drug Donanemab: Promising Results 34

SLOWING DISEASE PROGRESSION IS A SIGNIFICANT TRIUMPH

approximately 90% of amyloid plaque

believe that a combination of drugs

from the brain. By removing this toxic

targeting different aspects of the

The Alzheimer’s drug donanemab has

protein early in the disease process, the

disease process will be necessary to halt

shown promising results in a major

drug has been shown to reduce brain

cognitive decline effectively.

clinical trial, raising hopes that it can slow

damage and slow the rate of cognitive

the progression of the most common

decline in patients. While it does not

RISKS AND SIDE EFFECTS

form of dementia. Developed by Eli Lilly,

result in improvements, it has been

It’s important to acknowledge the risks

donanemab is an antibody therapy that

found to delay deterioration compared to

associated with donanemab. Significant

targets abnormal clumps of the protein

a control group that received a placebo.

side effects, including brain swelling

beta-amyloid, which are associated with Alzheimer’s disease. The drug works by

and bleeding, have been observed in

POTENTIAL BENEFITS FOR EARLY-STAGE PATIENTS

patients, although serious problems are

binding to these plaques and removing them from the brain.

The effectiveness of donanemab was

participants, both in the donanemab

observed to be more significant in

group and the control group, experienced

UNDERSTANDING THE NEW DRUG - DONANEMAB

patients in the early stages of the disease

fatal outcomes.

Although donanemab is not a cure, it

protein called tau in their brains. The

has demonstrated the ability to clear

results indicate that removing amyloid

approximately 90% of amyloid plaque

before tau spreads is crucial. Donanemab

from the brain. By removing this toxic

is administered through intravenous

protein early in the disease process, the

infusion every four weeks, and patients

drug has been shown to reduce brain

require regular brain scans to monitor

damage and slow the rate of cognitive

for potential side effects, including brain

decline in patients. While it does not

swelling and bleeding.

who had low levels of another harmful

result in improvements, it has been found to delay deterioration compared to

SIMILAR DRUGS IN THE MARKET

a control group that received a placebo.

It is worth noting that donanemab is not the only drug of its kind. Lecanemab,

RAPID ACTION AND BRAIN PLAQUE REDUCTION The effectiveness of donanemab was observed to be more significant in patients in the early stages of the disease who had low levels of another harmful protein called tau in their brains. The results indicate that removing amyloid before tau spreads is crucial. Donanemab is administered through intravenous infusion every four weeks, and patients require regular brain scans to monitor

rare. During the trial, a small number of

developed by Eisai, is another amyloidtargeting antibody therapy that works similarly to donanemab. The US Food and Drug Administration (FDA) granted accelerated approval to lecanemab earlier this year, while European and UK regulators are still reviewing the drug. Another approved drug, aducanumab, has faced concerns regarding cost and effectiveness, limiting its widespread use.

for potential side effects, including brain

A COCKTAIL APPROACH FOR DEMENTIA TREATMENT

swelling and bleeding.

While these drugs represent a breakthrough in directly affecting the

EFFECTIVE, BUT NOT A CURE

progression of Alzheimer’s disease, they

Although donanemab is not a cure, it

have modest effects. Many scientists

has demonstrated the ability to clear

Reference: NIA statement on donanemab results: More alzheimer’s research progress (no date) National Institute on Aging. Available at: https://www.nia. nih.gov/news/nia-statement-donanemab-resultsmore-alzheimers-research-progress (Accessed: 22 September 2023). Smyth, J. (2023) Two alzheimer’s drugs offer hope to patients after decades of waiting, Financial Times. Available at: https://www.ft.com/content/ b18aefc1-ccbc-442e-a23c-117f27826d71 (Accessed: 22 September 2023).

How might healthcare transform in the next 50 years?

THE TRANSFORMATION OF THE HEALTHCARE INDUSTRY:

The outbreak of the COVID-19 pandemic

Respondents provided answers to a

has dramatically altered the dynamics

series of follow-up questions. The initial

Over the past ten years, the healthcare

of healthcare. A resilient healthcare

round aimed to gather insights into

sector has undergone a profound

infrastructure is essential, capable of

opinions concerning current trends in the

metamorphosis, driven by factors such

managing large-scale health crises. For

healthcare industry and the key factors

as population growth and technological

example, appropriately programmed

projected to shape its future. Subsequent

advancements. This transformation has

robots have emerged as valuable assets

rounds, namely rounds 2 and 3, delved

significantly altered how the general

for tasks like diagnosis, risk assessment,

deeper into examining the signals and

public interacts with the healthcare field.

treatment monitoring, telehealthcare,

drivers influencing the healthcare sector.

There is an increasing demand for less

disinfection, and forecasting the spread

invasive medical treatments, ultimately

of infectious diseases. These innovations

improving the quality of life for patients.

have the potential to mitigate the rapid

People are seeking healthcare solutions

transmission of diseases. Both the

that are tailored to their specific needs

healthcare industry and society at large

and are financially accessible.

should be equipped to identify and comprehend recent healthcare trends.

Numerous scientific studies have

Recognizing these trends is crucial for

demonstrated a correlation between

anticipating the necessary capabilities

lifestyle choices and the development

and resources required to implement

of future illnesses. This has prompted a

novel healthcare delivery methods

shift towards emphasizing preventive

during emergencies.

medicine and overall well-being, rather than solely focusing on disease

THE STUDY:

treatment. The concept of personal well-

The primary objectives of this study were

being is becoming increasingly coveted,

threefold: (a) validate and revise major

particularly in developed nations.

developments in the field of medicine;

Contemporary trends are encouraging

(b) identify the key factors driving future

individuals to take more responsibility

medical innovations; and (c) anticipate

for their own health. In the modern era,

short-term, medium-term, and long-term

patients are no longer mere recipients of

progress in the medical domain.

care but active participants in achieving

The study employed the Delphi

better treatment outcomes.

method, consisting of three rounds

Wearable sensors have become

with expert feedback at the conclusion

commonplace, thanks to ongoing

of each round. A total of 22 medical

medical research and technological

experts were selected from seven

advancements. Additionally, startups

European countries, including doctors,

and major technology companies are

representatives from European medical

now venturing into the healthcare

associations specializing in various fields

sector, driven by the introduction of

(nine experts), members of academic

numerous health-related apps. This

institutions (seven experts), and other

consumerization trend has paved the

industry figures such as policymakers

way for new entrants into the healthcare

and business leaders (six experts).

industry.

NOTABLE EMERGING TRENDS:

Signal 1: Value-based healthcare, which

•

Stress: Recently, new sources of

focuses on improving patient outcomes

and extreme weather events are

stress have emerged, including

and optimizing resource utilization.

exerting a substantial impact on

sudden lifestyle changes, self-

This model emphasizes individualized

public health. The effects of global

isolation, and concerns about

approaches, close collaboration with

warming are expected to intensify in

the health and future of loved

caregivers, and streamlined decision-

the years ahead, with environmental

ones. Stress and uncertainty have

making through the integration of digital

pollution and climate change already

increased among 80% of workers,

technology.

driving transformative changes in

interactions, and interpersonal

Signal 2: Smart delivery of biologically

relationships.

active substances, highlighting the

Signal 1: Climate migrants, individuals

need for innovative and customized

compelled to leave their homes due to

Biohacking: Biohacking involves

therapies tailored to individual patient

the long-term impacts of climate change,

the implantation of small electronic

characteristics and needs. This approach

including factors like drought, rising sea

devices under the skin to monitor

is expected to find extensive use in

levels, and shifting seasonal patterns.

bodily functions more accurately.

clinical care, including cancer treatment. Signal 2: Low-carbon healthcare,

Biohackers contend that specialized

•

Climate Change: Climate change

healthcare.

affecting sleep quality, family

•

diets, drugs, and supplements can

Signal 3: Telemedicine has witnessed

which presents both a challenge and

enhance cognitive abilities, sex drive,

significant progress, particularly in

an opportunity. It involves innovating

physical fitness, and even slow down

response to the COVID-19 pandemic.

operational advancements in healthcare

the aging process.

Telemedicine and remote treatment

infrastructure to align with global climate

options are increasingly favored by

goals.

Medical Tourism: The global medical

patients, healthcare providers, and clinics

tourism market is expected to

for addressing medical challenges cost-

IN CONCLUSION:

experience significant growth

effectively. This trend is anticipated to

The researchers have meticulously

in the coming years. Individuals

shift the delivery of healthcare from

outlined and analyzed the key factors

often travel abroad to seek second

hospitals to patients’ homes in the post-

that will steer the evolution of the

opinions and access advanced

industrial era.

healthcare industry over the next halfcentury. Experts have provided their

healthcare infrastructure that may Data-Driven Personalization:

stamp of approval on the assumptions

Some also travel for participation

Data-informed personalization

regarding short-term, medium-term,

in medical experiments. Notably,

involves delivering the right

and long-term changes that are likely to

in December 2020, Indian tourism

interventions at the right time and

influence not only prominent industrial

operators reportedly arranged for

location based on individual patient

players but also society as a whole.

people to travel abroad to receive

data to diagnose, prevent, or treat

These findings emphasize the

COVID-19 vaccinations, marking the

diseases.

importance of stakeholders being

be lacking in their home countries.

•

prepared to offer adaptable responses

emergence of vaccine tourism. Signal 1: Smart hospitals, which

to events during this transitional

CRUCIAL INFLUENCING FACTORS IN THE HEALTHCARE INDUSTRY:

encompass efforts to improve the

phase in the healthcare industry. It is

quality of medical services, outsource

acknowledged that certain trends may

Researchers have identified three

vaccinations and laboratory services,

lose prominence, while others may

major factors that are poised to exert a

enhance patient engagement, provide

emerge as transformative forces.

considerable impact on the healthcare

more patient-centric care, and offer cost-

sector in the near future. These factors

effective treatments.

are wellness technologies, data-driven personalization, and climate change.

Signal 2: Wearable devices have emerged as noninvasive tools for collecting and

•

Wellness Technologies: Enhanced

interpreting vital patient data. These

well-being promotes creativity,

devices have shown significant potential

efficiency, peer relationships,

for improving patient health in fields such

longevity, and health. The survey

as cardiology, diabetology, and neurology.

participants ranked mental health as the most crucial indicator of overall health and well-being.

Reference: Saha, N. (2023) How might healthcare transform in the next 50 years?, News. Available at: https://www.newsmedical.net/news/20230112/How-might-healthcaretransform-in-the-next-50-years.aspx#:~:text=A%20 new%20study%20published%20in,driven%20 personalization%2C%20and%20climate%20change. (Accessed: 22 September 2023). Soffe, E. (2023) Interweave healthcare, Interweave Textiles Ltd. Available at: https://www. interweavetextiles.com/prediction-futuristic-hospitals/ (Accessed: 22 September 2023). (No date) Health care 2030: The coming transformation | nejm catalyst. Available at: https:// catalyst.nejm.org/doi/full/10.1056/CAT.20.0569 (Accessed: 22 September 2023).

AI prompts wave of medical tourism By Spencer-Jolliffe, N.

Every year, approximately 14 million

coming years, according to a Global Data

internet browsers and social media

people around the globe travel overseas

report. AI uptake and its future potential

platforms, increasing the number of

for medical treatment, accorting to the

is a leading trend in medical tourism and

medical tourists and the possibility of

Medical Tourism Association.

is expected to contribute to its growth.

reaching more.

often seen as a sub-segment of the larger

The proliferation of AI in medical tourism

A 2022 research study states that

health and wellness tourism industry,

has wider benefits for the healthcare

sectors throughout the travel and

where the purpose of travel is to maintain

industry too. Increasing access to lower-

tourism industry leverage AI to perform

an individual’s health and wellbeing

cost medical procedures advances the

various administrative and customer-

says Josep Bori, Research Director at

development of the medical device

related tasks. In medical tourism,

Thematics Intelligence. “However, it

industry across many markets, the

AI advancement “plays a key role in

is growing,” Bori tells Medical Device

GlobalData report asserts.

supporting the medical agencies in

Medical tourism is still a niche market,

Network. By 2024, the medical tourism

connecting physicians and prospective

sector is expected to be worth $27.6

ENGAGING AND INVESTING IN AI

million, up from $16.8 million in 2018.

Medical tourism involves significant

medical tourists”.

amounts of user information uploaded

Turkey has emerged as a leading

The biggest driver of medical tourism

to cloud management systems online.

destination for medical tourism. The JCI

is cost, as consumers are conscious of

AI technology is also used by medical

has accredited more than 45 Turkish

saving money, a spokesperson for Joint

tourists to arrange trips, removing the

hospitals and ranks second worldwide

Commission International (JCI), which

need to visit travel agencies to book

for the number of hospitals receiving JCI

provides internationally recognised

flights or search for accommodation.

accreditation.

standards, told Medical Device Network.

“AI assistants and intelligent chatbots

Healthcare costs have been rising

have now replaced health consultants

The United Arab Emirates (UAE) is

steadily in recent years and are expected

allowing travellers to book flights and

considered a leader in AI in medical

to grow at a 2.7% compound annual

accommodations and health packages,”

tourism, regulating its healthcare

growth rate (CAGR).

says Balta.

industry’s development by introducing the first AI policy. In addition, it has

Privacy, shorter waiting times, receiving

“AI underpins both advancements

created its UAE Artificial Intelligence

recommendations from friends or family,

in technology and quicker access to

Strategy and announced the world’s first

the opportunity to combine medical care

services.” Various AI capabilities extend

Minister of State for AI.

with a favoured vacation destination,

from foundational ones like machine

and a preference to receive care from

learning to advanced areas such as

Researchers anticipate that AI, a

a culturally similar provider are other

computer vision, decision making

technology of the Industrial Revolution

compelling reasons patients opt to

and motion. These AI capabilities

4.0 era, will progress global healthcare,

travel overseas for medical care, Şebnem

support many healthcare businesses’

enabling patients to receive more

Akman Balta, Owner of Medulux Health

processes and functions, such as patient

affordable and accessible medical

in Turkey tells Medical Device Network.

management and scheduling, medical

treatments overseas and reaching readily

diagnosis, surgery, and other operating

available health records in a real-time

theatre processes.

and secure way. However, “the growth

THE TIME FOR AI?

of health tourism raises the eyebrows

In recent years, seismic events have transformed medical tourism. The

Developing and integrating AI into cloud

of society from the security, social and

industry has suffered a loss of 850

systems enables social media platforms

economic perspectives,” according to

million to 1.1 billion international tourist

to track patterns and understand user

experts.

arrivals and $910 billion to $1.2 trillion

behaviours better, enabling them to

from export revenues from tourism

tailor content that appears on each

during the Covid-19 pandemic, a 2020

user’s interface rather than demanding

United Nations Conference on Trade and

proactive user-led engagement.

“AI seems to be the future of the

By analysing user engagement,

the technology’s focus on placing

Development report on Covid-19 and tourism states.

practitioners, hospitals, and agencies While socioeconomic factors such as

can use AI to reach prospective patients

the Covid-19 pandemic and the Russia-

around the globe by customising content

Ukraine war remain global threats to the

relating to medical tourism and medical

growth of medical tourism, the sector

procedures to reflect their needs. AI

is expected to continue to scale in the

enables targeted advertisements on

FUTURE OF AI IN MEDICAL TOURISM industry”, researchers have said, detailing consumers at the centre of health and wellbeing and ensuring healthcare professionals see patients’ daily patterns and needs to provide improved guidance, support and feedback.

“As far as AI and technology, particularly telehealth, JCI continues to watch/monitor it closely for impacts on quality and safety,” the spokesperson adds. However, the spokesperson stated that the JCI does not have specific insight or visibility on how AI is used in medical tourism, perhaps highlighting the technology’s nascent and niche role in the current sector. Exploring the role of data in the medical tourism sector, a 2023 research study found that data related to patients who travel overseas for planned medical care remain limited. AI may provide opportunities for medical tourism healthcare providers if they embrace the return of data to a central registry. Medical tourism is on the rise. “Thanks to AI technology, it will grow faster in the future,” Balta says. With the help of AI, hospitals and clinics can reach more patients online. Using AI can increase medical tourism providers’ promotion and reachability, leading to faster sector growth. References: Spencer-Jolliffe, N. (2023) Ai prompts wave of medical tourism, Medical Device Network. Available at: https://www.medicaldevice-network.com/ features/ai-prompts-wave-of-medical-tourism/ (Accessed: 20 December 2023).

An Interview with Dr Ben Chan “Whether you are stepping out into cosmetic medicine, or as a skin therapist you are seeking to expand your scope of practice, accessing credible education is the key. In today’s ever-changing world on-going professional development is essential for survival, as well as to hold your professional position in the highly competitive world of aesthetic therapies and cosmetic medicine.”

The Aesthetics and Skin institute (AS) is

We were delighted to interview Dr

a global training organisation based in

Ben Chan who shared with us how the

Australia, it offers both e-learning and

Aesthetics and Skin Institute is helping

hands-on courses to help you succeed

improve education and best practice.

as a confident, all- rounded aesthetics

DO YOU COVER AND WHAT KNOWLEDGE AND SKILLSOUTCOME CAN A GRADUATE EXPECT TO GAIN FROM YOUR TRAINING? Our educational and training program covers two streams -cosmetic medicine

threads, lasers, microneedling and

Q1: DR CHAN, CAN YOU PLEASE LET US KNOW WHAT KIND OF TRAINING YOU OFFER IS IT FACE-TO-FACE OR ONLINE STUDIES, OR BOTH?

working with various technologies.

Originally all of our training was face-to-

injectables theory and techniques and

Dr Ben Chan is the Clinical Director

face, as we focus on ensuring it is tailored

with 20% on skin therapies. On the other

who heads the AS. With over 30 years

to the individual needs. This is because

hand, a non-medical practitioner-beauty

of experience, he brings a wealth of

we train individuals across a diverse

therapists or dermal therapists would

knowledge in clinical practice. Together

range of professional backgrounds.

undertake the 100% skin therapies

with his competent team training is

However, we also include online

program. As there are several levels of

delivered through sound science-based

training and in recent times, we have

training available, all candidates also

education to empower practitioners

added training through Zoom sessions.

receive on-going mentoring support. This

to achieve exceptional results and

This allows the candidate to access

allows us to ensure their competence sp

best practice. Varying levels of training

personalised education regardless of

that it does not stagnate, but continues

cover a wide scope of practice available

their demographics.

to grow. Once someone takes the

practioner wherever you are. It offers a wide range of aesthetics and skin modules, which includes injectables,

to doctors, nurses, dentists and skin therapists

and skin therapies. For example, with doctors and nurses the focus is usually 80% on cosmetic medicine eg.

training into their clinical environment,

Q2: WHAT AREAS OF TRAINING

questions will arise, so we believe it is

important that we are avaiable to guide

AREA?

All our training programs are based on

the student during any challenges that

When training doctors and nurses in the

evidence-based science and they are

they may encounter. Additionally, as they

area of injectables the issue of ethnicity

also accredited by various bodies such

gain confidence, they may be ready to

is critical, as each ethnic group has

as ACRRM and also the APAN ARAP CPD

step their knowledge up to higher levels,

different needs. For example, Asians have

program.

rather than become stuck at a certain

wide cheek bones, however, they may

level. We therefore encourage them to

need a procedure that lifts their eyes A

open up to further learning once they

Caucasian may wish to lift the cheeks

master their current level of knowledge.

and create more volume for their mouth,

Q3: DR CHAN, PLEASE SHARE WITH US A LITTLE ABOUT THE SCOPE OF TRAINING THAT YOU OFFER AND THE VARIOUS PROFESSIONAL LEVELS?

whereas a South Asian-Indian or Sri Lankan may have full lips and not need enhancement in that area. It is important that an injector has

Our scope is very wide and covers

an understanding and examines the

fundamentals, as well as advanced

different structural needs as they

modalities. We cover skin science

will require different approaches and

in depth, as well as anatomy and

different outcomes depending on the

physiology, as these are very important.

ethnicity of each patient.

We then offer units in treatment options such as peels, skin needling,

Similarly, for treating the skin, each

SPL, Laser and several other equipment

ethnic category has different needs.

such as Radio-Frequency, as well as

For example, Middle Eastern skins often

different techniques. We also cover

suffer from melasma, while Indian ethnic

specific protocols in addressing various

groups often have concerns with dark

skin conditions and disorders such as

circles under their eyes and pigmentation

melasma. Additionally, we cover the

around the mouth. Darker skins also

correct clinical approach and sequence

have a tendency to scar more easily.

in intergrading various modalities. All our

Asian skins on the other hand, have less

techniques are based on sold science

concerns with wrinkles, but they dislike

and medical journal consensus of proven

the appearance of pores and they value

methodologies that work.

a very clear complexion with even colour

Q4: DO YOU ALSO OFFER POSTGRADUATE TRAINING FOR PROFESSIONALS WHO ARE AREADY WORKING ON THE SKIN

and no blemishes With Asian skins, while they have less wrinkles, they do have high levels of complications and reactions that a practitioner needs to be aware of.

Our training is not just for beginners or those who wish to enter the industry. We

All this information needs to be correctly

have advanced modules that move into

assessed to identify the different causes

more clinical practice and in dealing with

of the various concerns. The practitioner

more challenging skin conditions.

needs to apply the appropriate approach

Q5: WHEN IT COMES TO ETHNIC SKIN TYPES HOW IS YOUR TRAINING SPECIALISED IN THIS

for that skin, utilising different modalities and sequence of treatments to ensure successful clinical outcomes.

Reference: AESTHETICS AND SKIN INSTITUTE (2023) Skintech Medical - An Interview with Dr Ben Chan , Skintech Medical Cosmetic Clinic. Available at: https://skintech. com.au/about/ (Accessed: 26 September 2023).

TELL US ABOUT YOUR ORGANISATION AND ITS JOURNEY TO DATE? “RAK Hospital’s journey of the last 15 years has been immensely gratifying and inspiring, to say the least. Set up with a view to cater to the primary care needs of residents in the Northern Emirates, RAK Hospital soon spread its wings across the UAE and to international patients through its very supportive network and reliable references. Not just that, we have also been able to establish ourselves as the foremost centre of advanced tertiary care in the Middle East region.” With just 18 months from the groundbreaking ceremony to its inauguration, RAK Hospital has stood tall, since the beginning, for its innovative approaches to wellness and healthcare. Drawing inspiration from Sonnenhof Swiss Health (SSH) of Switzerland, which is renowned for excellence in healthcare combined with the highest levels of hospitality, we have created a unique model of healthcare rarely seen before in the region. The same is also reflected in our vision of establishing Ras Al Khaimah as the premium quality healthcare destination of the world. The success can be gauged by the fact that in the very first year, RAK Hospital won the Joint Commission International (JCI) of the US, and Swiss Leading Health (SLH) of Switzerland, the two most credible accreditors of healthcare facilities in the world. The list of these accolades has grown consistently year after year since then. The journey is dotted with several milestones. We have introduced various technological innovations to the UAE’s healthcare

sector bringing world-class treatments and surgical procedures of international standard right into the heart of the MENA region. Each year has witnessed the addition of something new to the hospital from its cutting-edge surgical

Dr. Raza Siddiqui Executive Director, RAK Hospital CEO, Arabian Healthcare Group 46

treatments to the strength and experience of the renowned medical team. As a result, RAK Hospital has become a popular medical tourism centre for complete and long-term medical solutions.

can reduce the burden of pandemics and

patients to travel abroad for advanced

HOW HAS THE ORGANISATION EVOLVED TO ADDRESS THE CHALLENGES OF AN EVERCHANGING HEALTHCARE SECTOR? PLEASE LIST SOME ACCOMPLISHMENTS

epidemics. Our RAK Hospital on Wheels

treatments. RAK Hospital is the only

is another pioneering initiative towards

healthcare institution in the entire MENA

bringing best-in-class treatment closer

region to be aligned with Dignity Health

to the low-income group population

International (DHI), CommonSpirit’s

of Northern Emirates. Our team of

international health representative,

Not so long ago, many patients from

expert medical professionals travel to

cementing the hospital’s position as a

Middle East would travel abroad due

various high-density residential areas

preferred medical destination for both

to the absence of advanced tertiary

in a custom-designed ‘Mobile Clinic’,

international and local patients. The

medical care facilities in the region,

equipped with world-class equipment

unique collaboration also heralds an

especially in the domains of cardiology,

and facilities, for offering superior

expansion of RAK Hospital, which would

neurology, orthopaedics and oncology,

medical services at a very affordable cost.

triple its capacity by 2024.

of its capable staff and reliable network

Through another groundbreaking

The key areas of collaboration with

of partners, has ushered in a new era

initiative, RAK Hospital has committed

CommonSpirit, which operates 140

of expert and best-in-class treatments

to training hundreds of security guards

hospitals and more than 1,500 care sites

available locally and entailing a gamut of

as first responders for emergency

across 21 US states, will include digital

healthcare services across 30 specialities.

situations. This first-of-a-kind initiative by

innovation, training and education,

Further to our strategic partnership

the institution aims to save thousands of

clinical alignment, care coordination,

with Dignity Health International (DHI),

lives by making First Aid readily available

network expansion and improving the

the international arm of CommonSpirit

to society. As part of this program, high-

overall patient experience. The capacity

Health, one of the largest hospital

quality BLS-certified Life Support training

enhancement would enable us to cater

systems in the US, our patients now

is provided free of cost to hundreds of

to the increasing influx of medical

have access to not just the world-class

security guards across Ras Al Khaimah.

tourists, as well as to meet the increased

protocols and practices right here in the

Give us an insight into your portfolio

demand for quality healthcare which

region but also to the best of experience

and solutions targeted at the Middle

will be created by the implementation

and expertise offered by physicians

East region. RAK hospital boasts a wide

of mandatory health insurance in the

across a strong network of 140 hospitals

multidisciplinary portfolio encompassing

Northern Emirates. The expansion will

in the US.

30 specialities, with a primary focus

equip us to serve local and international

but not anymore. RAK Hospital, by virtue

on cardiac services, neurosciences,

patients with high-quality care. Digital

We are also very proud of our

orthopaedics, musculoskeletal

and smart health practices that are

engagement with the community and

conditions, rehabilitation and select

successful in DHI network hospitals will

people, arising as an outcome of various

additional services.

also be implemented at RAK Hospital,

CSR initiatives undertaken by RAK

while the potential of artificial intelligence

Hospital. Courtesy of such programs, we

We are also developing an integrated

will be harnessed to create improved

continually develop a rich and in-depth

Patient Navigation Center on a hub and

patient experiences. In addition, a further

understanding of numerous healthcare

spoke basis, with the RAK centre as a

scale-up of telehealth services will be

challenges faced by society. This

hub and initial spoke centres spread

implemented to support the expansion

understanding, in synergistic conjunction

across Ghana, Kenya, Nigeria, Pakistan,

requirements.

with the clinical experience of our staff,

and Bahrain. Additionally, we would

enables us to design and introduce

set up Virtual Tumour Boards enabling

many community-care programs aimed

consultation and diagnosis of complex

at spreading awareness and education

cancer cases while allowing our patients

about preventive lifestyle and proactive

to stay close to home.

healthcare. Our COVID-19 awareness drives, rehabilitation programs as well as RAK Biggest Weight Loss Challenge and RAK Diabetes Challenge are some examples of such initiatives which have made a huge difference to the way people deal with various lifestyle-related ailments. We have proved that having a holistic perspective and management protocol

WHAT WILL YOU BE SHOWCASING AT ARAB HEALTH 2023? Our main endeavour at Arab Health 2023 will be to highlight the advancements in tertiary medical care available now

TELL US ABOUT YOUR RECENT AND UPCOMING INVESTMENTS AND PARTNERSHIPS IN THIS FIELD

to patients in the Middle East region

Besides our ongoing partnership

our strengths and medical tourism

with The Swiss Leading Hospitals, we

capabilities through our network

are also very excited about the new

of strategic partnerships. The key

strategic partnership with Dignity

highlight would be the display of Patient

Health International. These associations

Navigation Centres being developed in

enable us to provide best-in-class

association with DHI, which will provide

tertiary medical care to the society in the

patients and their clinicians access to

region, thus minimising the burden on

through our hospital, medical centres and labs. We would also be showcasing

exceptional clinical expertise across

industry and we are totally geared up for

CommonSpirit’s affiliated network,

that. Furthermore, we will continue to

and further, support patients seeking

augment our community outreach by

healthcare services in one of the

providing constant motivation, guidance

CommonSpirit’s centres of excellence

and education to society, so they are

in the United States. Through this

fully equipped to take a proactive charge

integrated Patient Navigation Center,

of their health. We also look forward to

we will help patients identify the most

introducing some novel techniques in

appropriate CommonSpirit facility for

the domain of cardiac care and neurology

treatment and also manage and provide

departments as well as enrichment of our

continuity for pre and post-care. Clinical

overall service offerings.

teams from both health systems will be able to coordinate care virtually thus reducing the burden of medical travel for regional patients.

IN ADDITION TO THE ABOVE, WHAT OPPORTUNITIES ARE YOU LOOKING FORWARD TO AT THE UPCOMING EVENT? Arab Health is one of the most popular health events globally. With a footfall of 30,000+, it provides us with the opportunity of highlighting several of the milestones achieved by RAK Hospital during the last 15 years. We are sure that our participation in an event of such a magnitude would constitute another giant stride towards fulfilling our vision of establishing Ras Al Khaimah as the preferred destination for premium medical care in the world. We are definitely looking forward to meeting industry peers from across the world, exchanging knowledge, showcasing our capabilities and forging new ties to grow further.

ANYTHING ELSE YOU WOULD LIKE TO ADD? With a burgeoning healthcare industry, the UAE has been exemplary in offering treatments at par with high international levels. RAK Hospital too has been at the forefront of this endeavour and has been instrumental in bringing the latest innovations in the medical field to the UAE. The hospital which was envisioned, designed and built with the aim to bring to the region top-class medical expertise, will continue to add more value to the UAE medical scene, adding to its growth and stability. I wish all the participants of Arab Health 2023 and the society at large a very healthy and successful 2023. Reference: Interview with Dr. Raza Siddiqui, Executive Director, RAK Hospital and CEO, Arabian Healthcare Group (no date) Interview with dr. Raza Siddiqui, executive director, RAK Hospital and CEO, Arabian Healthcare Group. Available at: https://www.arabhealthonline. com/en/visit/leaders-in-the-spotlight/dr-raza-siddiquirak-hospital.html (Accessed: 26 September 2023).

PLEASE TELL US ABOUT YOUR PLANS FOR THE YEAR 2023 Having successfully been in operations for the last 1.5 decades, which has seen RAK Hospital evolving from a family care institution to one of the best tertiary care providers in the region, we are well poised to custom expand our capacity in the most befitting manner to the needs of Middle Eastern society. In 2023, we aim to build further on the partnership with DHI and expand further the portfolio of medical care services in the region. The roll-out of mandatory health insurance in the Northern Emirates will also herald a new era for the healthcare sector bringing positive changes to the

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