The Lundbeck Foundation 2011 Report

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2011 ANNUAL REPORT


Grete Lundbeck

THE LUNDBECK FOUNDATION – AN ACTIVE INDUSTRIAL FOUNDATION Hans Lundbeck founded the company H. Lundbeck in 1915. In 1954, his widow, Grete Lundbeck, established the Lundbeck Foundation and transferred her shares in H. Lundbeck to the Foundation as the couple had no heirs. Today, H. Lundbeck is a world leader in the development and sale of drugs to treat brain disorders. H. Lundbeck was listed on the Copenhagen Stock Exchange in 1999, and the Foundation owns 70% of the company. In 1989, the Lundbeck Foundation acquired its second subsidiary, and today owns 40% of the capital (67% of the votes) in ALK, the world leader in allergy vaccines. Finally, in 2011, the Foundation bought 57% of the leading international rescue and assistance company, Falck. In addition to the three subsidiaries, the Foundation owns and manages a portfolio of securities worth approx. DKK 10 billion (€ 1.4 billion) via Lundbeckfond Invest, as well as a portfolio of biotech investments managed by Lundbeckfond Ventures. Throughout its history, the Lundbeck Foundation has made grants to independent research in biomedicine and natural sciences with ties to Denmark. The amounts involved have increased significantly in recent years, and in 2011 reached DKK 504 million (€ 68 million) of which € 1 million went to “The Brain Prize” awarded by Grete Lundbeck’s European Brain Research Foundation.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

CONTENT

An eventful year with many initiatives

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Grants - The year in brief - Strategy and governance - Prize and fellowship recipients - Theme: Genetic research alleviates pain and guilt - Theme: Neuroscience Centres

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Commercial activities - The year in brief - Corporate governance - H. Lundbeck - ALK - Falck - Lundbeckfond Invest - Lundbeckfond Ventures - Social responsibility, risk management and future expectations

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Consolidated financial statements Parent foundation financial statements the Lundbeck Foundation The Lundbeck Foundation Centres The Lundbeck Foundation Fellows

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Chief Executive Officer Christian Dyvig and Chairman of the Board Mikael Rørth

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

2011 – AN EVENTFUL YEAR WITH MANY INITIATIVES 2011 was a landmark year for the Lundbeck Foundation on many fronts, e.g. with the acquisition of the international rescue and assistance company Falck, changes to its grant strategy and management. The acquisition of a third subsidiary has long been on the Foundation’s agenda, and the acquisition of Falck has both strengthened and diversified the Group’s financial foundation. 2011 was also the year when, for the first time, the Foundation made grants of more than DKK 500 million (€ 68 million) to research. Commercial activities The Lundbeck Foundation Group’s total revenue grew by 39%, from DKK 16.9 billion (€ 2.3 billion) in 2010 to DKK 23.6 billion (€ 3.2 billion) in 2011, primarily due to the acquisition of Falck. Positive progress was also seen in group operating profit before tax and special items (EBIT). In 2011, EBIT was DKK 4,165 million (€ 560 million) compared to DKK 3,513 million (€ 473 million) in 2010 – an increase of 19%, again primarily driven by the acquisition of Falck. The Foundation’s share of the profit for the year before special items of DKK 1,815 million (€ 244 million) represented a decline from the previous year (DKK 2,880 million (€ 387 million) in 2010). This was due to negative results totalling DKK 142 million (€ 19 million) in Lundbeckfond Invest and Lundbeckfond Ventures, compared to a profit in 2010 of DKK 1,124 million (€ 151 million), while the subsidiaries improved their financial performance. The result for the Foundation is acceptable given that the decline in portfolio investments was caused by external factors, particularly the development in the global stock markets. H. Lundbeck After a record turnover in 2010 of DKK 14,765 million (€ 1,986 million), H. Lundbeck again managed to increase sales in 2011 to DKK 16,007 million (€ 2,153 million), corresponding to 8% growth despite the commencement of patent expiring for the antidepressant Cipralex/Lexapro and the resulting generic competition in a number of markets. In 2011, H. Lundbeck increased the sales of other products by 12% to DKK 7,315 million (€ 984 million). Late in the year, the company launched three new products and filed additionally two applications for the registration of new products. Overall, these initiatives will increase sales of other products significantly in the coming years. The most important new initiative in 2011 was, however, the establishment of a joint venture within psychiatry with the Japanese company Otsuka. The agreement confirms H. Lund-

beck’s position as a leading global player in pharmaceuticals for treatment of brain disorders. Operating profit (EBIT) showed a slight improvement at DKK 3,393 million (€ 456 million) in 2011 compared to DKK 3,357 million (€ 452 million), driven by increased sales and improved efficiency in production. The full impact of the company’s initiatives is not reflected in the results due to non-recurring costs for the reorganisation of research and development activities, as well as costs associated with the Otsuka agreement. Profit for the year at DKK 2,282 million (€ 307 million) compared to DKK 2,466 million (€ 332 million) in 2010 was down as a result of increased tax payments. ALK During 2011, the Foundation increased its stake in ALK. At year-end, it held 67% of the votes in the company and 40% of the capital. ALK’s turnover increased by 9% to DKK 2,348 million (€ 316 million) compared to DKK 2,159 million (€ 290 million) in 2010, partly due to milestone payments from its partners. In early 2011, ALK received a large upfront payment from Torii upon conclusion of an agreement regarding sales in the Japanese market. The collaboration with Merck (USA) regarding the North American market also developed positively in 2011. Merck thus made milestone payments to ALK and has presented impressive results from their studies of ALK’s products against grass and ragweed allergies. Operating profit (EBIT) rose to DKK 299 million (€ 40 million) compared to DKK 192 million (€ 26 million) in 2010. Profit for the year increased to DKK 200 million (€ 27 million) compared to DKK 128 million (€ 17 million) in 2010. Falck In 2011, the Foundation acquired 57% of the highly respected international rescue and assistance company, Falck. After the acquisition, Falck has continued its positive development and follows the plans upon which the Foundation based its invest-

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

ment – apart from the Brazilian ambulance activities, which Falck has closed down. Lundbeckfond Invest In connection with a change of strategy in 2011, the management of the Foundation’s portfolio investments was renamed Lundbeckfond Invest. The strategy for Lundbeckfond Invest involves increased active internal management of the portfolio, combined with some specialised external managers for selected assets and index investments of the rest of the portfolio at low cost. The new strategy of active internal management has been progressively implemented in 2011 and will continue in the coming years. Lundbeckfond Invest manages approx. DKK 10 billion (€ 1.4 billion). Its financial performance in 2011 was strongly affected by the global financial turmoil. The result for Lundbeckfond Invest in 2011 was a loss of DKK 72 million (€ 10 million) compared to a profit of DKK 1,179 million (€ 159 million) in 2010. Lundbeckfond Ventures Since its inception in early 2010, Lundbeckfond Ventures has established itself as a life science investor both in Europe and America, and has extended a wide network of contacts within the pharmaceutical and biotech industries. Based on the positive initial experience with Lundbeckfond Ventures and in light of the global lack of venture capital for biotech companies, the Board of the Foundation decided in 2011 to expand the capital committed to Lundbeckfond Ventures. The Foundation considers this an attractive and important area for future investment. The Foundation’s intention over the coming years is to continue to expand Lundbeckfond Ventures’ organisation and create a strong international investor and partner for the biotech industry. In 2011, Lundbeckfond Ventures invested in three new companies that are working to respectively develop transcranial magnetic stimulation for the localisation and stimulation of various brain functions, pharmaceuticals to treat the side effects of cancer treatment, and a new, natural bone substitute. In line with incentive programmes for the venture industry, an incentive programme was introduced at Lundbeckfond Ventures in order to continue to attract and retain skilled and qualified personnel in this specialist area. Equity and net wealth The overall impact of developments in the Group’s activities is that the Foundation’s share of consolidated equity grew from DKK 21.4 billion (€ 2.9 billion) to DKK 22.6 billion (€ 3.0 billion), while the Foundation’s net wealth at market prices rose from DKK 28.5 billion (€ 3.8 billion) to DKK 28.7 billion (€ 3.9 billion). The Foundation receives annual dividends from its subsidiaries, which are used for consolidating the Foundation and the financing of grants.

Grants Grants in 2011 increased by 31% to DKK 504 million (€ 68 million) from DKK 384 million (€ 52 million) in 2010, which is the highest amount the Foundation has ever awarded in a single

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year. The Foundation has continued to award application based regular grants to research within biomedical and natural sciences of approx. DKK 300 million (€ 40 million). In the context of the regular grants, the Foundation has increased its focus on young research talent by raising the number of Lundbeck Foundation Fellowships (worth DKK 10 million/€ 1.3 million each) from five to seven per annum. Strategic grants have increased to DKK 205 million (€ 28 million) from DKK 104 million (€ 14 million) in 2010. The main area of focus is centred around the theme “Brain Disorders are Biology”, given the unique research opportunities in Denmark for combining clinical research with gene-sequencing data and information from health and social registers. The Foundation has awarded the largest-ever single grant for psychiatric research in Denmark to the major national interdisciplinary project, iPSYCH. Furthermore, the Foundation has extended the collaboration with the neuroscience centres that were established in 2005. In this report we follow-up on the research findings from these three centres, as well as the neuroscience centre established in 2008. All four have made extremely gratifying progress. Finally, the Foundation has expanded its funding preferences to include allergy and immune modulation, as per its objective of supporting the research that forms the basis for the activities of the subsidiary ALK. Lundbeckfond Emerge In early 2012, the Foundation launched a new initiative, Lundbeckfond Emerge. The ambition is to create a bridge between university-based research and the commercial world. This will be done both by providing grants to start ups and by supporting researchers in academic communities with operational and industrial competences as well as with making the decisions necessary to develop research results and product ideas, with a view towards building a company or creating other kinds of commercialisation.

The Foundation’s operations The Lundbeck Foundation’s day-to-day operations are based on a rigorous governance structure that is embedded in the organisation. The aim is to ensure that the Foundation meets its objective of, on the one hand, being an active, valueadding owner and investor and, on the other hand providing grants to research within biomedical and natural sciences with ties to Denmark. In order to ensure the quality of the research funded by grants, the research areas and the funding methods are clearly defined and announced. The Foundation mainly uses external experts, in the form of internationally renowned researchers who, through their peer review and assessment of project applications, ensure that the projects supported by the Foundation are of a high international standard. The most important criterion for awarding grants is thus the quality of the research and the difference that it can make to people’s health and well-being. In relation to the subsidiaries, good governance requires a thorough understanding of the companies’ markets, products and services as well as keeping up to date with their opera-


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

tions. By doing so, the Foundation aims to be a good sparring partner for the companies’ management. In 2011, the Foundation’s governance structure has again proven its worth via this year’s sizeable grants, which include support for the iPSYCH project, and via the subsidiaries’ continued impressive development. The Foundation continuously seeks to minimise its operating costs, which in 2011 in total amounted to DKK 42 million (€ 6 million). This includes the total cost of operations of Lundbeckfond Invest, Lundbeckfond Ventures, grant-making activities and administration, including the monitoring of subsidiaries. The cost of Lundbeckfond Invest was DKK 6 million (€ 1 million), equivalent to 0.06% of assets under management. The cost of Lundbeckfond Ventures was DKK 7 million (€ 1 million), equivalent to 2.0% of invested capital. Costs associated with grants were DKK 7 million (€ 1 million), equivalent to 1.5% of the awarded amount, while the administrative and monitoring costs in 2011 amounted to DKK 22 million (€ 3 million). Directors’ fees for the Foundation and its wholly owned subsidiary amounted to DKK 4 million (€ 0.5 million), and executive remuneration was DKK 3 million (€ 0.4 million). Both members of the Board and the Chief Executive Officer of the Foundation are active on the boards of the Group’s partly owned subsidiaries. Total fees to Board members and Chief Executive Officer amounted to DKK 7 million (€ 1 million) and DKK 4 million (€ 0.5 million), respectively.

financial reporting are also noteworthy, as is the success in securing for the Foundation its third subsidiary, in the form of Falck. Steen Hemmingsen will maintain his relations to the Foundation through board representation in Falck and ObelLFI Ejendomme, and in connection with a project including the history of the Foundation. We wish to express our gratitude to the retired Directors and the Chief Executive Officer for their long-standing and significant contributions to the development of the Foundation. -oChief Physician, Professor Mikael Rørth MD was elected new chair (formerly deputy), and Group CEO, Civil Engineer Jørgen Huno Rasmussen replaced him as deputy. Christian Dyvig LLM MBA was employed as Chief Executive Officer of the Foundation. Finally, on behalf of the Board of Directors and the Management, we would like to welcome two new Board members: Professor Povl Krogsgaard-Larsen, Pharm.D. and Professor Gunhild Waldemar, Chief Physician, M.D. We have already benefited greatly from their considerable insight and experience. On behalf of the Foundation, we thank all participants on assessment committees and our partners at universities and in the ministries for their invaluable co-operation in 2011. We look forward to an equally good and eventful 2012.

The Foundation is jointly taxed with its subsidiaries through the wholly owned subsidiary Lundbeckfond Invest A/S. The Group’s total tax expense for 2011 was DKK 1,100 million (€ 148 million), and DKK 468 million (€ 63 million) was paid in Denmark. Words of thanks to the retired leadership At the annual meeting in 2011, the chair, Mogens BundgaardNielsen, announced his resignation from the Board. Under his chairmanship, the Foundation’s work has increased significantly, particularly in relation to the acquisition of Falck and the establishment of Lundbeckfond Ventures. Furthermore, the grants to research within biomedical and natural science has increased. Mogens Bundgaard-Nielsen has retained links to the Foundation as a board member of the Grete Lundbeck European Brain Research Foundation, which awards “The Brain Prize” (€ 1 million).

Mikael Rørth Chairman of the Board of Trustees

Christian Dyvig Chief Executive Officer

Chief physician Nils Axelsen MD also retired from the Board. Through his very broad research insights, Nils Axelsen has contributed significantly to the Foundation, not least in connection with the expansion of the grant activities. He has been the driving force behind establishing the Grete Lundbeck European Brain Research Foundation, which he currently chairs. The Chief Executive Officer of the Foundation, Steen Hemmingsen, also elected to retire after 11 years in office. In that period, the Foundation has undergone a huge development in both its commercial and grant-making activities, with investment funds multiplying eight-fold and grants 17-fold. Furthermore, the strengthening of the Foundation’s governance principles regarding the Board, grants and developments in

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Anne-Marie Engel, Director of Research

GRANTS – THE YEAR IN BRIEF In 2011, the Lundbeck Foundation allocated grants worth DKK 504 million to 350 projects. The Foundation received 1,426 applications for a total of DKK 2.74 billion.

Key data Funding is divided into two main categories. Regular grants are allocated to projects, Lundbeck Foundation Fellowships, research prizes, travel grants, visiting professorships and projects that focus on research into science teaching. DKK 299 million was awarded in this category. The Foundation also focuses on strategic initiatives. Within the parameters of the Foundation's overriding grantmakingstrategy, the Board identifies particular fields of research with the aim of funding major projects in which the expertise of multiple Danish and international research teams converges to define projects with strong potential for ground-breaking scientific discoveries. DKK 205 million was granted in this category.

DKK million. Regular grants 299 Biomedical projects 182 Natural sciences projects 26 Fellowships 70 Visiting Professorships 3 Teaching projects 12 Travel grants 2 Research prizes 1 Other projects 3 Strategic initiatives 205 iPSYCH 121 Continuation of 2005 Neuroscience Centres 84

In 2011, the focus was on psychiatry and a major grant of DKK 121 million was awarded to a partnership, iPSYCH, involving researchers at Aarhus University and the Mental Health Services, Capital Region of Denmark. Funds were also granted for the continuation of the three neuroscience Centres of Excellence established in 2005.

Total 504

Following the grant-making strategy, which can be read on page 8, the Foundation seeks to reward excellence in research with a connection to Denmark. In 2011, the Board revised the grant-making strategy, and there are now two focus areas within biomedicine: neuroscience/psychiatry and allergology/ immune modulation. Following on this decision, the Foundation will focus on major projects within both neuroscience/ psychiatry and allergology/immune modulation when determining the future strategic priorities.

Internationalisation of Danish research If Danish research is to maintain its current level or improve its position in international rankings, local research environments must build up and maintain strong international partnerships. The Foundation contributes to such network activities within biomedicine by funding Visiting Professorships for up to six months at Danish biomedical research institutions. Seven such grants were provided for basic and clinical research in 2011. Funding is also provided to facilitate international collaborations of individual Danish researchers. The Foundation is parti-

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

cularly keen to fund prolonged research visits abroad by highly qualified Danish researchers and research visits to Denmark by scientists from abroad. This year, the Foundation granted DKK 11 million to 12 such researchers who travelled abroad and to three who visited Denmark. DKK 220 million to Lundbeck Foundation Fellows Since 2007, the Foundation has awarded five-year fellowships worth DKK 10 million each to a total of 22 researchers from Denmark and abroad who have reached a point in their career where they are ready to establish their own research teams and focus on projects that they themselves have defined. In 2011, seven new fellows joined this group of young research leaders, who will undoubtedly help define Danish front-line research in the years ahead. What Lundbeck Foundation Fellows have in common is that they have to make the change from being part of a team to leading their own team at very short notice. In 2011, Associate Professor Maja Horst ph.d., Head of the Department of Media, Cognition and Communication at the University of Copenhagen, therefore on behalf of the Lundbeck Foundation ran two workshops for fellowship recipients to talk about how to combine work on their research with the challenges of leading a team of researchers.

In 2011, the establishment of a Danish satellite to the EMBL (European Molecular Biology Laboratories) was facilitated by a DKK 120 million grant from the Lundbeck Foundation. In 2012, following a call for applications, the Danish Council for Independent Research will be in charge of an international peer review, define evaluation criteria and identify international evaluators. Based on this, the Foundation will decide which university will host the Danish satellite of this prestigious European basic-research partnership. Denmark will then join Sweden, Norway and Finland in the Scandinavian collaboration with EMBL. Theme articles Biology and thereby genetics as a base for mental illness is the theme for the discussion between Royal Actor Henning Jensen and Professor of Psychiatry Thomas Werge in the following article. Furthermore, the heads of the Foundation's four neuroscience Centres of Excellence discuss what will be considered their most significant contributions to research in years to come.

Strategic initiatives A grant of DKK 121 million was made to the first three years of iPSYCH, a major interdisciplinary project focusing on psychiatric research. It is the largest ever grant to psychiatric research in Denmark. The project is headed by five leading Danish researchers in psychiatry, genetics and data research, who will establish collaborations with Statens Serum Institute, Beijing Genomics Institute, deCode Genetics from Iceland and the Faroese biobank. The research seeks to map the biological mechanisms that lead to the development of mental health problems, and to use this knowledge as a basis for the development of improved treatment of serious mental illness, and for preventive measures. Science teaching In 2011, the Foundation granted DKK 8 million to two research projects focused on education and training of science teachers in primary and lower-secondary schools. The projects are designed to generate new concepts for the training and in-service training of science teachers. The main feature of the projects is collaboration between the university colleges and the universities on the development of teachertraining programmes. New activities in 2012 In 2012, the Foundation's strategic projects will continue to focus on psychiatric research, but strategic projects within the area of allergology/immune modulation will also be identified. The News Department at the Experimentarium will receive funding to enhance media coverage of Danish biomedical and natural sciences research. Also, a new function has been added to the Foundation's funding activities: Lundbeckfond Emerge. An innovation scout with expertise in biotechnology will visit Danish universities and provide both funding and advice for the further development of research projects with high commercialisation potential.

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Make a significant difference

Support quality research at the highest level

Increased internationalization and interest in science

Focus on young researchers

Preference for neuroscience, psychiatry & allergology/immune modulation

Ties to Denmark

GRANTS – STRATEGY AND GOVERNANCE The Lundbeck Foundation is an industrial foundation that strives to make a significant impact on people’s health and well-being by funding research of the highest international quality, conducted both in Denmark and involving Danish scientists abroad, and primarily within biomedicine and natural sciences

Funding scheme The Foundation supports independent research in biomedicine and natural sciences. Young researchers are given precedence, and - all other things equal – biomedical priorities are neuroscience, psychiatry and allergology/immune modulation. The Foundation promotes the internationalisation of Danish research by funding partnerships and exchange programmes involving leading research teams from Denmark and abroad. The Foundation endeavours to motivate, inspire and recognise research talent, e.g. by presenting honorary awards and fellowships. Smaller-scale funding of school projects that encourage an interest in science is another integral part of the Foundation's activities. Funding categories Regular: Grants for research into biomedicine and natural sciences are awarded in open competition (“bottom up”). Strategic: Innovative research in strategic areas determined by the Board for periods covering several years and implemented by the Foundation through specific programmes. Research funding The overriding criterion for the Foundation’s research funding is that the scientific content of the application, the applicant's qualifications and the academic environment at the host institution are all of top quality. The Foundation systematically evaluates both applications and the results generated by the

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research projects that it funds. Applications are processed by peer-review panels with a majority of external experts. As a general aim, grants must make a tangible difference. Therefore, large grants are generally allocated to a small number of projects, rather than smaller amounts to a large number of projects.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

PRIZE AND FELLOWSHIP RECIPIENTS 2011 THE LUNDBECK FOUNDATION FELLOWS

Associate Professor, ph.d. Jan Arlt

Assistant Professor, ph.d. Mariola Monika Golas

Guest Professor, ph.d. Rune Linding

Assistant Professor, ph.d. Niels Emil Jannik Bjerrum-Bohr

Post doc., ph.d. Himanshu Khandelia

Associate Professor, ph.d. Albin Sandelin

TALENT PRIZES

M.Sc., ph.d. Magnus Kjærgaard

Research fellow, ph.d. Martin Snoager Sloth

RESEARCH PRIZE FOR YOUNG SCIENTISTS

Post doc., ph.d. Thomas Just Sørensen

Assistant Professor, ph.d. Søren Egedal Degn

Professor, ph.d. Tamás Freund

Professor, ph.d. György Buzsáki

Professor, D.Sc. Eske Willerslev

THE BRAIN PRIZE

Professor, ph.d. Péter Somogyi

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GENETIC RESEARCH ALLEVIATES PAIN AND GUILT Mental illness has a biological foundation, about which we have learned a great deal in recent years. What role does it play for someone with a mental illness – and what does it mean for the researchers – that there are so many other approaches to mental disorders?

Danish researchers have been working closely with colleagues from private and public institutions throughout the world in recent years to find and identify more of the mutations in the human genome that increase the risk of developing severe mental illness. Their discoveries have paved the way for a new understanding of the interaction between genetics and environment, and expectations are high that this research will have a crucial impact on future understanding and treatment of people with mental disorders. “The first really credible breakthrough came in 2008, when we first managed to dig into the genome physically and ascertained that specific changes make individuals predisposed to disorders such as schizophrenia and autism. Bipolar disorder was added to the list later on. This may still be virgin territory but since 2008, the idea that mental illness has a heredity element has no longer been a mere theory. Mental illness is just as biological as blood pressure and diabetes,” says Thomas Werge, Professor and Head of Research at the Research Institute of Biological Psychiatry, Mental Health Centre Sct. Hans. In a Copenhagen café, Werge meets Royal Actor Henning Jensen, who has suffered from severe depression and has talked openly about it for the last decade. Their conversation ranges over research, guilt and pain. It's all about guilt Everybody hopes that research will lead to new forms of treatment but for Thomas Werge that isn't the crux of the matter – guilt is. “When parents watch their children become mentally ill, the sense of guilt is overwhelming. Admitting to high blood pressure is one thing but nobody feels at ease saying 'my husband suffers from schizophrenia' or 'my child has ADHD'. Everybody knows something's badly wrong, but the subject is totally taboo.” Werge acknowledges that the home environment does have an impact on your psychological and mental development, but it isn't the main driving force.

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“For me it's about removing the concept of guilt. Guilt has absolutely no place in the equation. But it weighs so heavily it's impossible to fathom.” For Werge, some of the most satisfactory experiences in his professional life have been lecturing in relatives' and patients' associations and witnessing the strong reactions from parents of children with severe mental illnesses. Specifically, he remembers a lecture in the spring of 2009, when a group of parents told him that they felt as if they had been 'liberated' from guilt. “A mother with two daughters, the oldest of whom suffered from schizophrenia, had always thought she was to blame for the girl's illness. Her youngest daughter had been physically ill for a prolonged period, and this mother thought that because she had been caring for her, the older sister had been neglected, and that was why she contracted schizophrenia. Imagine spending your whole life feeling guilty about your children. That's awful. If genetics can help overcome that sort of pain, it will have made a colossal impact.” Understanding is liberating Henning Jensen, who has suffered from severe depression, is full of praise for the new research breakthroughs. He agrees with Thomas Werge that they mean so incredibly much to the families and to those who suffer from mental illness. "When I finally realised, after many years, that it’s partly chemistry that triggers depression, I felt liberated. When I'm out talking to people about it they seem so relieved when I bring it up." But this sense of liberation only followed after many long and difficult years, during which Jensen battled with his condition, and, not least, with an enormous sense of guilt. "As a depression builds, you feel as if you've no right to live, that you're not a person like everybody else, and that you’re unworthy of being in the presence of others." Jensen reached a point where he regretted everything. He distanced himself from his every past action and attitude.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Eventually, it reached a stage where he had almost wiped out his entire life in a kind of suicide attack on his own past and being. “And just think, when I was discharged from hospital and was back out among other people, it took three years before I spoke to anybody about it. Three years! It was as if there was this silent agreement –as if mutual silence meant it had never actually happened. After three years, a stage director asked me what had happened back then.” In 2001, Henning Jensen decided to go public with his story, as part of a national information campaign about depression. Since then, he has held some 150 lectures all over Denmark. “For me, it means the world to accept myself for who I am, without feeling guilt, without having to hide half of myself from the world. I've applied this knowledge in real-life during a new bout of depression a couple of years back when I found myself pacing up and down the beach in Raageleje and telling myself: You have every right to be here, you're a human being,

you've got just as much right to be here as anybody else. And suddenly the fear melted away. I have to say that you researchers and your public pronouncements make it much easier to be a patient and carry that latent depression, that’s always there and always will be. It's been a relief that you were able to pin some scientific facts onto mental disease,” Jensen says.

”For me it's about removing the concept of guilt. Guilt has absolutely no place in the equation. ” Thomas Werge, Professor of Psychiatry

Henning Jensen and Thomas Werge

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THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Depressed mice But what exactly are these facts? "Well, we haven't yet reached an understanding of what exactly it is in the brain that triggers mental illness. Genetics opens up interesting new horizons because we've never actually had a lot of ways of getting inside the brain. For a century, we've discussed what schizophrenia is, how it differs from autism, for example. Actually, as it is now, your diagnosis can change if you hop on a plane to America, because they have a slightly different classification system than in Europe," Thomas Werge explains. "But since we've now managed to put our finger on a few of the genetic changes that may make individuals predisposed to severe mental illness, we can induce those same changes in mice and study how the mutations alter their brains. We think we are onto something fundamental about mental illness. If we are, new medication may be developed based on whole new understandings. And then medical treatment of mental illness will be all about prevention or cure. This is totally different from the methods previously used to develop drugs for mental illness. "There are multiple models, but one of the most widely used depression models is to give a mouse electro-shock,” Werge explains. “You give it electro-shock at one corner of the cage, so it moves to the other corner. You repeat the procedure until the mouse is completely apathetic and just stands there staring out into space. Based on its behaviour, you now diagnose this as a depressed mouse. You treat it and if something works, then you claim to have found something that works on depression. The new knowledge we've gained in recent years makes it less important how the animal behaves, because now we're able to measure directly the effect of disease mutations in its brain and try to correct the biological mutations that we find.” Negotiating in a minefield Thomas Werge has encountered a wide range of reactions to animal testing and is curious to know if it raises Henning Jensen's hackles that biological changes are recreated in animals producing, for example, depressed mice. “No. Not in the slightest. Quite the contrary. If we weren't able to do that we'd still be living in the trees. I'm happy that you don't have to experiment on me to learn about the genetic causes of depression,” replies Jensen, who is actually more interested in knowing what the time horizon is for new forms of treatment. “We are looking at a time horizon of five years just to work out the potential in the new animals that we're working on. So we're talking about the next generation of people with mental illness benefiting from new drugs,“ Werge explains. “Will this mean bona fide genetic engineering?” Jensen wants to know. "I envisage drugs that attack the genetic causes of disorders and either compensate for them or correct them without actually tampering with the patient's genes. The furthest I envisage us going with actually touching genes would be

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”When I finally realised, after many years, that it’s partly chemistry that triggers depression, I felt liberated.” Henning Jensen, Royal Actor

prenatal diagnosis, which is already used to check for other genetic conditions," Werge replies. The potential for prenatal diagnosis means the new research has to negotiate in a minefield of ethical discussions and attitudes, and Thomas Werge has encountered some strong reactions. "When the research was first made public in 2008, some people talked about eugenics and genetic engineering. I even received letters addressed to me as SS Obersturmführer. It's not up to me to decide whether we should introduce prenatal diagnosis. That's a deeply ethical decision that basically is up to the individual. But an opportunity is emerging to advise mentally ill patients who'd like to have children and healthy parents who have mentally ill kids. We have examples of parents whose first child became severely ill at a very young age, and now they're not sure whether they dare have any more. In situations like that we would actually be able to provide meaningful genetic counselling,” Werge says. Henning Jensen does not belong to the group that is worried by the idea of prenatal diagnosis. Quite the contrary in fact. “The more the better, I say. Of course, nobody wants a society of robots, where everybody looks the same and we are all completely regimented. But I do know from my own experience that as far as mental illness is concerned, some kind of diagnostics is preferable to just abandoning people to a living hell.” Conflicting genes All this talk of genes leaves Henning Jensen mulling over his own genetic make-up. “We've talked a lot about genes. Actually, I've often thought my own genes were in conflict with each other, if I can put it like that. My parents were about as different as you can get, and since I'm the product of both, it has sometimes been difficult to reconcile the two. But one thing both sets of genes did agree about was me becoming an actor. So any defects there may be in my genes are also the raw material for my life as an actor. When I'm up there on the stage, I'm in balance. I really am. Totally. And it's always been like that,” he explains. “It's funny that you should say 'defects' in your genes,” Werge interjects.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

“There are a lot of common genetic differences between humans. And, in fact, a part of this normal genetic make-up may predispose to mental illness. This helps to provide us with an understanding of the fact that mental illness may well just be the extreme ends of normal behaviour. It's normal to be afraid – we have to be afraid sometimes and run for it. It's probably not a bad idea to have periods where you take things a bit slower, and other periods where you do things a bit faster.”

“Wouldn't it be great to have Niels Bohr's penchant for abstraction, you might ask. Well yes, if you're also just as down-to-earth as he was. Because if you had Bohr's ability to abstract but weren't as down to earth as he was, you'd soar and fly like a helium balloon. All of the abilities that we are equipped with, must fit together. If they're not in balance, it all goes wrong.

As far as schizophrenia is concerned, Werge points out that 70-90% of us have the genetic variants that cause the condition but only a very small minority actually develop mental problems. Since these genetic variants are so widespread, research has concluded that they must also do something positive.

"In the depths of a depression once, I thought a lot about the fact that so many billions of people seem to get by just fine in a mentally balanced state, despite the fact that the slightest imbalance can throw you over the edge. The human brain really is the most outstanding piece of precision engineering.”

Too much of a good thing “So one way to think about mental vulnerability is that maybe you've got too much of a good thing. I use this argument with parents who blame themselves for their kids' conditions. It helps take the stigma out of the situation if they know that they've given their offspring too much of certain genetic variants, which are basically good for humanity, but just don't work so well for a tiny minority of us,” Werge explains. He uses the famous Danish physicist Niels Bohr as an example.

The idea of balance is not new to Henning Jensen.

Henning Jensen is often asked if learning so much about himself as he must have done during his depressions hasn’t been rewarding. But as he puts it – “The answer is no. I'd rather have lived a totally superficial and happy life without the knowledge I possess now. The pain was unfathomable. I haven't learned anything from my illness. But I've learned to live with it.”

13


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

MIND, Aarhus University The Lundbeck Foundation Centre for Membrane-Receptors in Neuronal Disease Management: Professor Claus Munck Petersen and Professor Anders Nykjær Granted 2005, DKK 50 million

A CHANCE DISCOVERY The world is crying out for a breakthrough in the way neurological conditions like bipolar disorder and ADHD are treated. The chance discovery that served as the catalyst for the establishment of the Lundbeck Foundation Research Centre for Membrane-receptors in Neuronal Disease (MIND) may turn out to hold the key to just such an effective new form of treatment. Professor Claus Munck Petersen's research career took a new turn about 18 years ago, when the results of a laboratory experiment he was conducting revealed the presence of a protein that nobody had ever encountered before. His curiosity piqued, Munck Petersen set about identifying this mysterious protein. Barely a year later, human brain samples confirmed that he had indeed discovered a brand new protein, a receptor produced in mammals' brains, which turns out to play an important role in the well-being of the human brain. He named this protein sortilin. Claus Munck Petersen soon established a partnership with Professor Anders Nykjær, and the duo have dedicated their lives to finding out what sortilin and its related molecules (sortilins) actually do. In 2005, they received a financial boost from the Lundbeck Foundation and were able to set up MIND. “MIND made it possible for us to progress systematically as part of an interdisciplinary team that brings together five smaller groups at Aarhus University. We now know the precise structure of a very central part of this receptor family and we also know how a lack of sortilins in the brain affects behaviour in mice,” Munck Petersen explains. Their experiments revealed that a lack of sortilins lowers the pain threshold in mice, alters their level of activity and impairs their memory. In other words, sortilin plays a role in key brain functions. The team now suspects that the receptors also play an important role in staving off neurological and psychiatric disorders such as Alzheimer's, ADHD and bipolar disease. 14

“The evidence suggests that defects in this particular receptor system can trigger the development of a number of neurological disorders. It cannot be ruled out that our findings could ultimately lead to new medicines to treat those conditions," he explains. Professor Munck Petersen still has to pinch himself whenever he thinks about all the things that his chance discovery and early partnership with Anders Nykjær have led to. “What started out with a single ph.d. student and a laboratory technician has paved the way for a whole new field of research. 100 scientists from 20 countries attended the conference that we hosted in summer 2010. The Centre sets the agenda in its field, and we intend to do everything in our power to maintain that leading position,” he concludes.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

LUCENS, Glostrup Hospital, University of Copenhagen The Lundbeck Foundation Centre for Neurovascular Signaling Management: Professor Jes Olesen Granted 2005, DKK 30 million

FROM RESEARCH CENTRE TO NEUROLOGICAL HOSPITAL The fact that the Lundbeck Foundation Centre for Neurovascular Signaling (LUCENS) was established there in 2005 is one of the main reasons why Glostrup Hospital has developed into a specialist neurological hospital, according to the Head of the Center, Professor Jes Olesen.

When LUCENS opened under Professor Olesen, Glostrup Hospital already had plans to reorganise and focus more closely on neurological conditions. The professor is in no doubt that LUCENS helped facilitate the transformation, which has made Glostrup home of the largest neurological department in Denmark and one of the biggest in Europe. “The grant from the Lundbeck Foundation was the fuel that powered the process and made it possible to turn the big plans into reality. It is one of the reasons why we now have special clinics focusing on neurological conditions like epilepsy, Parkinson's disease, dementia, apoplexy, headaches and eye disorders,” Jes Olesen explains. He also points out that LUCENS has assumed huge importance for the scientific infrastructure in the hospital and made it possible to conduct world-class translational research. “LUCENS helped us set up a research park with state-of-the art laboratories. It means that when we just can't tease any more information out of brain scans on patients in the hospital, we can go straight to the research park and dig deeper with the help of animal models,” he continues.

why migraines occur and of potential ways of treating them more effectively. “We have found that two neurotransmitters, CGRP and PACAP, which are produced in the brain and elsewhere in the body, affect migraines. If you give these substances to migraine patients, it provokes attacks because one of their actions is to cause a slight distension of the blood vessels in the brain,” the professor explains. The researchers at LUCENS now know which specific receptors the neurotransmitters affect. “The challenge now is to use this knowledge to develop medicine that will alleviate pain during migraine attacks,” he says. Jes Olesen is convinced that Glostrup Hospital will be remembered 25 years from now for hosting the world's leading headache centre. “Because that is what it will still be then!” he promises with a smile.

“We don't have to wait for other researchers to take the initiative when we make new discoveries in our patients. We can do it ourselves.” Olesen's own research speciality is headaches, and LUCENS has helped him and his colleagues gain a clearer picture of 15


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

CIMBI, Copenhagen University Hospital The Lundbeck Foundation Centre for Integrated Molecular Brain Imaging Management: Professor Gitte Moos Knudsen Granted 2005, DKK 40 million

CLOSING IN ON WINTER DEPRESSION The Lundbeck Foundation Centre for Integrated Molecular Brain Imaging (CIMBI) is narrowing down the mechanism in the brain that triggers depression during the dark winter months in the cold North. The research revolves around light and the serotonin system.

Most people in the Nordic Region are well aware that winter is a season of mood swings. The dark months can provoke anything from a mild dose of the winter “blues” to a full-blown winter depression. In this altered state of mind people need more sleep, they crave carbohydrates and they find it more difficult to get things done at work and at home. The researchers at CIMBI have made important progress towards understanding this seasonal state of mind. Brain scans of healthy individuals have been used to study the impact on the serotonin system of the changing seasons and the amount of light. The serotonin system is known to play a key role in a wide range of psycho-physiological functions, including mood, aggression and pain. The interesting point about the research is the revelation that the serotonin system is affected by the seasons, i.e. it works differently in summer than in winter. “Serotonin and its related receptor system are part of the key to our state of mind, which may well explain why we undergo major mood swings – or even suffer full-blown winter depression – during the dark months,” explains the Head of CIMBI, Professor Gitte Moos Knudsen, who is well known in international scientific circles for her work on the serotonin system. CIMBI has gone a step further, revealing that seasonal mood swings also depend on our genes. “We are now looking at whether the gene variant that triggers particularly pronounced seasonal fluctuations in healthy individuals has a similar effect on people who suffer from winter 16

depression and are unable to regulate their serotonin system as the seasons change,” the professors adds. The center is closing in on what triggers winter depression, and light and brain chemistry are the main suspects. “We hope that we will be remembered 25 years from now as the people who got to the bottom of what exactly happens in the chemistry of the brain when someone is hit by winter depression. If we succeed, we will have solved a major social problem. At present, about one in twenty persons in the Nordic Region develops full-blown winter depression, and a much larger number experience pronounced mood changes during the dark months. It is detrimental to their quality of life and reduces their ability to do their best,” she concludes. CIMBI is also developing brand new radioactive tracers capable of measuring serotonin activity in the human brain. The tracers are used in PET and MRI brain scans to analyse what happens in the brain when, for example, we feel sad, impulsive or ready to take a risk.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

CINS, Glostrup Hospital, University of Copenhagen The Lundbeck Foundation Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research Management: Professor Birte Glenthøj Granted 2008, DKK 30 million

INDIVIDUALISED SCHIZOPHRENIA TREATMENT Changes to the brain's reward system are not the only mechanism that triggers hallucinations and delusions in patients suffering from schizophrenia. Other structures and signalling systems also play a role, according to new research by the Lundbeck Foundation Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS). The goal is that one day the research will lead to individualised treatment.

Schizophrenia has long been thought of as an umbrella term covering multiple disorders that affect different structures and signalling systems in the brain rather than being a single condition. However, despite indications that this is the case, the research world has lacked solid scientific evidence to go on. CINS has changed all that. It conducted the first ever study of a large group of patients before treatment with anti-psychotic medicine, and followed up with new brain scans once treatment had commenced. The results of the scans and of other advanced methods of examining how the brain processes input yielded important new information about the condition, e.g. that medicine, and perhaps substance abuse, are not the only factors that can induce changes in the schizophrenic brain. Actually, the condition itself leads to changes in the part of the brain's reward system that is associated with psychotic symptoms. “These findings are of huge significance to our understanding of the way in which psychotic symptoms such as hallucinations and delusions develop in schizophrenic patients,” explains Professor Birte Glenthøj, Leader of CINS.

symptoms such as delusions. In some patients, changes in the brain's serotonin system induce similar symptoms. “This is important. It tells us that different sub-types of schizophrenia exist that respond differently to different treatments. For example, it means that some patients would benefit from having their serotonin 2A receptors blocked and others from having their dopamine D2 receptors blocked. It opens the prospect of individualised treatment at some point in the future,” Professor Glenthøj adds. The research has already led to a revision of treatment guidelines in hospitals, e.g. accentuating how the individual patient should be treated in order to alleviate symptoms such as delusions and hallucinations. The professor hopes and expects that CINS will be remembered 25 years from now for the part it played in making schizophrenia a less “mysterious” disorder and how this encouraged greater overall understanding of the condition.

The reward system is pivotal to the onset of schizophrenia, and the neurotransmitter dopamine plays a key role in this. Dopamine is the body's own happiness drug. It is released into the brain when we are expecting to experience something good like money, sex or delicious food. CINS is also challenging the previously accepted idea that changes to the dopamine system are the only way to provoke 17


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

COMMERCIAL ACTIVITIES – THE YEAR IN BRIEF The commercial activities of the Lundbeck Foundation Group focus on the three subsidiaries (the strategic investments), which are complemented by portfolio and venture investments managed by the Foundation through Lundbeckfond Invest and Lundbeckfond Ventures.

development and the launch of new products. ALK recorded higher revenue and profit in spite of major investments in developing new tablet products. Both H. Lundbeck and ALK made significant investments in 2011 in research and development and the launch of new products both in the near and the long term. As a result, the Group's combined research and development costs rose by DKK 364 million in 2011 to DKK 3,775 million. The subsidiaries' increased focus on launching new products also had an adverse impact on the Group's operating profit (EBIT) owing to higher marketing expenses. There was an increase of DKK 652 million in the Group's EBIT because both H. Lundbeck and ALK, despite higher costs, managed to increase their EBIT, and also because of the consolidation of Falck.

Activities and results for the year In terms of earnings, 2011 was not on the same level as 2010 for the Lundbeck Foundation Group because of a loss in Lundbeckfond Invest. In 2011, the Group acquired the shareholding majority of Falck, and Falck was consolidated as a subsidiary of the Group at 1 July. The combination of the consolidation of Falck and higher revenue in the subsidiaries H. Lundbeck and ALK materially pushed up the Group's total revenue, which rose from DKK 16.9 billion in 2010 to DKK 23.6 billion in 2011, an increase of 39%. H. Lundbeck recorded an increase in revenue in 2011 but a flat development in profit due to investments in research and

GRANT ACTIVITIES

70%

Specialized pharmaceutical company developing innovative treatments for brain disorders

40%* (67%)

Global leader in allergy vaccines

* The Lundbeckfoundation holds 40% of the capital and 67% of the votes in ALK.

18

57%

International leader in assistance and emergency services

Portfolio investments of approximately DKK 10bn

Investments in biotech companies


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP KEY FIGURES

Financial highlights (DKK million)

2011

Revenue Operating profit (EBIT) Net financial items Lundbeck Foundation's share of profit for the year before special items Lundbeck Foundation's share of profit for the year

2010

2009

2008

23,602 16,927 15,594 4,165 3,513 2,877 -374 1,083 1,301 1,815 2,880 2,756 1,614 2,880 2,756

2007

13,381 12,823 2,448 2,920 -1,783 562 -608 1,888 -608 1,888

Grants awarded during the year 504 384 340 328 281 Equity 26,332 25,967 22,399 19,774 21,056 Lundbeck Foundation's share of equity 22,551 21,396 18,574 16,371 17,531 Total assets 47,459 34,732 32,109 23,588 25,000 Investments in acquisitions 4,537 178 5,133 129 Investments in property, plant and equipment and intangible assets 1,563 989 1,471 1,427 918 Net wealth (DKK billion) 28.7 28.5 26.1 27.6 33.3 Key figures Revenue growth EBIT margin Return on equity before special items Average number of employees

2,497

2,880

-383

-25 Administration

3

1,179

-55

Total

Grants

Before grants

Tax

Total

Grants

Before grants

Tax

Administration

Ventures

Invest

0 Invest

-498

1,000

0 Special items

Ventures

1,116

-29

-70

-72

-201

1,500

500

Falck

THE LUNDBECK FOUNDATION'S SHARE OF PROFIT 2010

0

1,614

78

76

2,000

500

ALK

13.0% 22.8% 11.8% 6,535

Special items

2,500 238

2,500

1,594

3,000

H. Lundbeck

4.4% 18.3% -3.6% 6,671

0

DKK MILLION

3,000

1,000

16.5% 18.4% 15.8% 7,048

In 2011, the Foundation made grants in the all-time high amount of DKK 504 million, against DKK 384 million in 2010, underlining the Foundation's ambition to make substantial contributions to research.

3,500

1,500

8.5% 20.8% 14.4% 7,314

The Lundbeck Foundation Group had tax expenses of DKK 1,100 million in 2011, against DKK 899 million in 2010.

3,500

2,000

39.4% 17.6% 8.3% 15,875

Falck

THE LUNDBECK FOUNDATION'S SHARE OF PROFIT 2011

2007

Operating expenses in the Foundation rose to DKK 42 million in 2011 from DKK 37 million in 2010 because of an overall increase in the number of employees, higher pension provisions and higher costs for administration and monitoring of subsidiaries.

H. Lundbeck

DKK MILLION

2008

50

The loss recorded by Lundbeckfond Ventures in 2011 rose by DKK 15 million to DKK 70 million, and was primarily due to

2009

ALK

Lundbeckfond Invest recorded a total loss of DKK 72 million, against a profit of DKK 1,179 million in 2010. The large fluctuation from 2010 to 2011 is ascribable to Lundbeckfond Invest's exposure to the equity markets, which plunged in 2011. Lundbeckfond Invest recorded a negative return of 1% in 2011, against a positive return of 9% in 2010.

2010

the adverse price performance of listed shares in which Lundbeckfond Ventures has invested.

1,728

The Lundbeck Foundation's share of profit for the year before special items amounted to DKK 1,815 million in 2011 and DKK 2,880 million in 2010. Special items amounted to DKK 362 million in 2011 and related to Falck's amortisation of intangible assets and costs associated with acquisitions.

2011

19


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

The Lundbeck Foundation's share of net profit is composed of income totalling DKK 1,594 million from H. Lundbeck, DKK 76 million from ALK and DKK 238 million from Falck, a loss in Lundbeckfond Invest of DKK 72 million, a loss in Lundbeckfond Ventures of DKK 70 million and administrative, monitoring and grant expenses of DKK 29 million. In addition, the Foundation's grants of DKK 504 million are deducted, less withdrawn grants of DKK 6 million. Net wealth Based on shareholdings in the listed subsidiaries and associates recognised at market value and other assets and unlisted shares recognised at carrying amount less payable grants etc.,

net wealth as of 31 December 2011 amounted to DKK 28.7 billion, against DKK 28.5 billion at the end of 2010. Movements in net wealth primarily consist of the performance of H. Lundbeck's share price, dividends from H. Lundbeck and grants. The share prices of both H. Lundbeck and ALK recorded a fairly flat trend in 2011 (H. Lundbeck 1.8% and ALK -0.2%) on average, but with major fluctuations over the course of the year. The flat price performance was notably better than the Danish NASDAQ OMX C20 index and the global MSCI All World Index, but compared with the international MSCI World Pharma Index, the performance was weak, although this was primarily due to the appreciation of the US dollar towards the end of the year.

NET WEALTH

Value

Asset

(DKK million)

allocation

14,834

50%

H. Lundbeck ALK

1,290

4%

Falck

3,277

11%

Invest

9,943

34%

267

1%

Ventures Payable grants etc.

(883)

Net wealth

n.a.

28,728

SHARE PRICE DEVELOPMENT 2011

RETURN 2011

DKK 150 140

130

H. Lundbeck

1.9%

ALK

-0.2%

120

MSCI World Pharma (DKK)

-0.2%

110

MSCI All World (DKK)

-13.6%

100

NASDAQOMX C20

-14.8%

90 80 70 Dec/10

20

Feb/11

Apr/11

Jun/11

Aug/11

Oct/11

Dec/11


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

MANAGEMENT AND CORPORATE GOVERNANCE The Lundbeck Foundation is managed by a board consisting of six elected members and three staff representatives from the two companies H. Lundbeck and ALK. The Board appoints the Chief Executive Officer of the Foundation.

The Foundation has joined the UN Global Compact. The Foundation has drawn up guidelines for its grants, including the recipient’s obligations to comply with the Foundation’s rules for scientific social responsibility.

The Board is self-supplementing. Ordinary elections are held at the AGM. Staff representatives are elected by the employees as per the procedures stipulated in Danish legislation.

The Board is subject to self-evaluation, in the form of dialogue between the chair and individual members, followed by discussions involving the entire Board. The executive management is evaluated at separate meetings.

The six elected members serve for a year at a time and are eligible for re-election for up to a maximum of 12 years and up to a maximum age of 75. If necessary, exceptions may be made to this rule to guarantee the desired overall competence profile of the board. The Board elects a chair and deputy chair immediately after the AGM. The Foundation yearly holds a minimum of four meetings plus a two-day seminar at which the Foundation’s strategy is discussed and decided upon. The Board has set up a research committee and an investment committee, which meet when necessary, at which time more detailed analyses and discussions are conducted on grant and investment issues. However, all decisions regarding grants and major investments are taken by the full Board. In the Foundation’s subsidiaries, a minimum of half of the members elected at the AGM, usually including the chair, must be independent of the Foundation. The Foundation closely follows the progress of the subsidiaries and seeks to be a good owner and sparring partner for their management, while exerting influence exclusively through representation on their boards and at general meetings. The Foundation considers it important that the companies have qualified and dynamic management teams that are capable of developing the companies and generating value for all shareholders. The CEO of the Foundation usually sits on the subsidiaries’ boards of directors, typically as deputy chair, while the chair of the Foundation is not a member of the subsidiaries’ boards. Rules of conduct have been implemented regarding potential conflicts of interest in relation to grants and investments as well as for board members and coworkers in relation to the Foundation’s grants.

21


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Lundbeck is an international pharmaceutical company engaged in the research, development, production, marketing and sale of pharmaceuticals targeted at disorders in the central nervous system (brain disorders), including depression and anxiety, psychotic disorders, epilepsy and Huntington’s, Alzheimer’s and Parkinson’s diseases, mainly based on own research. According to the World Health Organization, WHO, more than 700 million cases of brain disorders are reported every year. These are serious and life-threatening diseases that affect the quality of life of the patients as well as of their relatives. Further, these diseases also involve major socio-economic costs.

2011 business development 2011 was in many ways defined by the development of the partnering and collaboration strategy. Further, 2011 was another year of positive progress in the development portfolio, including the approval of two new products. Partnerships and collaboration agreements 2011 was a defining year for H. Lundbeck’s partnerships and collaboration agreements with entering new ones as well as realising the market potential of existing partner agreements. Successful partnering strategy In 2011, Lexapro® was launched in Japan by Mochida Pharmaceutical in collaboration with Mitsubishi Tanabe Pharma. The launch was the direct result of the partnership agreement Lundbeck signed with Mochida in 2002 concerning the development of escitalopram for the Japanese market. Over the course of the years, Lundbeck has received milestone payments and will now receive a prearranged royalty payment, which is a substantial percentage of the combined revenue in Japan. The launch is a milestone in the history of H. Lundbeck, given that it is the first H. Lundbeck product to be marketed in Japan. In 2010, Lundbeck acquired the rights to Saphris®/Sycrest® (asenapine) in all markets outside the US, China and Japan from US-based Merck & Co., Ltd. The launch of Sycrest® for the treatment of manic episodes associated with bipolar disorder was initiated in the European markets in 2011 and will continue in 2012. Outside Europe, Saphris® is indicated for the treat-

22

ment of both manic episodes associated with bipolar disorder and schizophrenia. The launch has been initiated in several markets in Asia, Australia and Canada, and more countries will follow in 2012. New collaboration agreements At the beginning of 2011, Lundbeck signed an agreement with US-based Cephalon, (now Teva Pharmaceutical), regarding the commercial rights in Canada and Latin America to six products with indications in brain disorders and cancer, including Treanda® (bendamustine HCI) for the treatment of chronic lymphocytic leukemia (CLL) and indolent nonhodgkin lymphoma (NHL). The registration procedures for several of the products have commenced. In November 2011, Lundbeck signed a strategic partnership agreement with Otsuka Pharmaceutical. The agreement covers the development and commercialization of pharmaceuticals for the treatment of psychiatric disorders. Under the terms of the agreement, Lundbeck is granted co-commercialization rights in all areas outside Asia, Turkey and Egypt for two of Otsuka’s high-potential compounds; aripiprazole depot and OPC-34712. Aripiprazole depot is developed for the treatment of schizophrenia. An NDA has been accepted by the U.S. Food and Drug Administration (FDA). In Europe, the compound is in clinical phase III, and the expectation is to submit an Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) in the first half of 2013. OPC34712 recently entered clinical phase III studies in schizophrenia and depression. The agreement with Otsuka also involves an option to enter into co-development and co-commercial-


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

DKK million Revenue Research and development costs EBIT Profit for the year The Lundbeck Foundation’s share of profit for the year Average number of employees

2011 2010 16,007 14,765 3,320 3,045 3,393 3,357 2,282 2,466 1,594 5,690

1,728 5,689

ization of up to three of Lundbeck’s early stage compounds in certain geographical regions. The economic consequence of the agreement is among other, that H. Lundbeck will pay up to DKK 9.7 billion to Otsuka in sales, development and regulatory dependent milestone payments over the coming years. Pipeline progress In October 2011, Onfi™ (clobazam) for the treatment of Lennox-Gastaut syndrome (epilepsy) was approved by the FDA. In January 2012, H. Lundbeck launched Onfi™ in the US. The clinical phase III programme for nalmefene for the treatment of alcohol dependence was completed in 2011, and an MAA to the EMA was submitted in December 2011. Reply from the authorities is expected at the end of 2012. Subject to approval, nalmefene will be marketed under the brand name Selincro™ and will become the first pharmaceutical in the market for the treatment of alcohol dependence that helps to reduce alcohol intake. 2011 result Revenue for the year rose by 8% to DKK 16,007 million. The improvement was driven by increasing sales of Ebixa® for the treatment of Alzheimer’s disease and Azilect® for the treatment of Parkinson’s disease (+14% and +15%) and Xenazine® for the treatment of Huntington’s disease and Sabril® for the treatment of infantile spasms (+40% and +73%). Sales of Cipralex® against depression continued to impress in 2011, growing 3% in spite of increased generic competition in several countries and the withdrawal of the product from the public market in Germany. Sales of Lexapro® increased 4%.

Research and development costs for the year amounted to DKK 3,320 million, or 21% of revenue, which was an increase of 9% compared to 2010. Sales and distribution costs for the year amounted to DKK 4,017 million equal to 25% of revenue and an increase of 15% compared to 2010. Administrative expenses amounted to DKK 2,111 million equal to 13% of revenue and an increase of 11% compared to 2010. Operating profit (EBIT) was DKK 3,393 million, corresponding to an increase of 1% relative to 2010. The EBIT margin was 21.2% compared to 22.7% in 2010. The profit includes a milestone payment of approximately DKK 200 million from Mochida relating to the launch of Lexapro® in Japan and income of DKK 95 million from the sale of the production facilities in Seal Sands in the UK. The profit also includes a DKK 364 million write-down relating to the restructuring of the research and development organization. The effective tax rate for 2011 was 30.8%, consistent with the expected tax rate of 30-32%. The effective tax rate rose from 25.0% in 2010 primarily due to valuation of tax assets. Profit for the year decreased 7% to DKK 2,282 million. The Lundbeck Foundation’s share of profit for the year amounted in 2011 to DKK 1,594 million compared to DKK 1,728 million in 2010 and the Foundation received DKK 479 million in dividends.

23


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

ALK is a research-driven global pharmaceutical company focusing on allergy treatment, prevention and diagnosis. The treatment is based on immunotherapy. Patients are exposed to the allergen in the form of an allergy vaccine. This restores the normal tolerance in their immune system and provides a sustained reduction in the symptoms and potentially halts the development of allergies and asthma. ALK is an international leader in the development of tablet based allergy vaccines. The first tablet product, Grazax®, is approved in Europe, while tablets for other allergies are currently in the clinical development phase.

2011 business development For ALK 2011 was defined by strategic partnerships and initiation of groundbreaking studies.

son, the number of patients was approximately 4,300 in the 17 completed clinical studies with GRAZAX® conducted in the period 2001-2011.

Partnerships In 2011, ALK entered into a partnership agreement with Torii Pharmaceutical to develop, register and commercialise MITIZAX®, among other products, in Japan. The agreement also covers ALK’s existing injection based vaccine and diagnostic products against house dust mite allergy. Moreover, the agreement includes a research and development collaboration targeting an allergy immunotherapy tablet (AIT) against Japanese cedar pollen allergy. In Japan, allergy to house dust mites and cedar pollen are the most frequently occuring allergies. It is estimated that 25-35 million people suffer from allergy or asthma caused by house dust mites or cedars. On entering into the agreement with Torii, ALK received a payment of DKK 224 million in 2011. The North American partnership with Merck continued in 2011 with among other Merck announcing positive results of the American studies of tablet based treatment of grass and ragweed allergies.

In Europe, ALK is conducting the clinical study called the GRAZAX® Asthma Prevention or GAP study. This study, which is the largest ever of its kind, is designed to investigate the potential of the product to prevent the development of asthma in children and adolescents. Studies of allergic children have shown that they are up to seven times more at risk of developing asthma. The GAP study will run for five years in 11 European countries and will include approximately 800 children aged 5-12 years. The study is progressing as planned and is expected to be completed in 2015.

Pipeline progress In 2012, the development of ALK’s products will reach a historically high level. It is expected that more than 8,000 patients will be participating in the clinical studies in 2012. In compari-

24

In 2011, ALK’s partner in North America, Merck, initiated a North American phase III clinical study to evaluate the efficacy of grass AIT (GRAZAX®) versus placebo in the treatment of grass pollen-induced allergic rhinocojunctivitis. The study includes 1,500 patients and is the largest ever conducted for grass AIT. The study is expected to be completed in 2012. In 2011, ALK decided to accelerate the development of tablet based treatment of house dust mite allergy – MITIZAX® in Europe and initiate an additional phase III clinical study (the MERIT study) to broaden the therapeutic use of the product. The MERIT study is a phase III study, and it is intended to enrol


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

DKK million Revenue Research and development costs EBIT Profit for the year Lundbeck Foundation’s share of profit for the year Number of employees

2011 2010 2,348 2,159 455 366 299 192 200 128 76 50 1,724 1,612

approximately 900 adults across 86 centres in 12 European countries. The study will evaluate the efficacy and safety of the treatment of house dust mite induced allergic rhinitis. ALK is also conducting the MITRA study, which is a phase III study enrolling up to 800 patients across 105 centres in 12 European countries to evaluate the efficacy and safety of the tablet in the treatment of house dust mite induced allergic asthma. This study is expected to be completed in 2013. 2011 result Revenue in 2011 increased by 10% to DKK 2,348 million (2010 DKK 2,159 million). The growth in vaccine sales was 5%, driven by the performance in France, the Netherlands, Spain, the Nordic countries and the USA. Vaccine sales accounted for 81% of total revenue, with the remainder being contributed by sales of adrenaline and diagnostic products, as well as revenues from partnerships. Operating profit (EBIT) increased by 56% to DKK 299 million versus DKK 192 million in 2010, which is the highest level in ALK’s history. The profit was extraordinarily high and was positively affected in particular by milestone payments from the partners Torii and Merck, which in 2011 contributed DKK 248 million against DKK 19 million in 2010.

was related particularly to a high level of clinical and pharmaceutical activities, including the GAP study and initiations of European clinical studies with MITIZAX® and AVANZ®. Added to this was support for the strategic partnerships in North America and Japan and new regulatory requirements in Europe imposing stricter requirements for the documentation of the company’s non-registered product portfolio, especially in Germany. Sales and marketing expenses amounted to DKK 781 million equal to 33% of revenue. Administration expenses were DKK 204 million equal to 9% of revenue and down by 2% compared to 2010. Income tax for the year amounted to DKK 121 million, corresponding to an effective tax rate of 38%. The profit for the year was thus DKK 200 million. The Lundbeck Foundation’s share of net profit for the year was amounted in 2011 to DKK 76 million compared to DKK 50 million in 2010 and the Foundation received DKK 20 million in dividends in 2012. The Lundbeck Foundation increased its ownership in ALK during 2011 to 40% of the capital and 67% of the votes.

Research and development costs increased by 24% to DKK 455 million against DKK 366 million in 2010. The increase

25


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Falck is a leading international supplier of pre-hospital services, healthcare, firefighting, roadside assistance and other contingency services, with operations on five continents and in 33 countries. Falck has four divisions: Assistance (roadside, personal and home assistance), Emergency (ambulance and fire service), Healthcare (medical clinics, healthcare employee assistance programmes for companies and pension funds and healthcare staff supply service) and Training (offshore safety and emergency training). All of Falck’s activities are aimed at preventing accidents and illness, providing assistance in case of accidents and emergencies, and helping people to get on with their lives after illnesses or accidents.

New ownership In July 2011, Nordic Capital’s seven-year ownership of Falck ended after the Lundbeck Foundation, Kirkbi and other investors acquired the company. The Lundbeck Foundation bought 57% of the shares in Falck in two stages. Business development in 2011 In 2011, Falck came substantially closer to achieving its goal of becoming a worldwide organisation that works to prevent accidents, illness and emergency situations; that rescues and assists people in an emergency quickly and competently; and that rehabilitates people after illness and injury. Falck has expanded geographically in all of its four business areas, especially Emergency. Emergency Falck’s emergency activities in 2011 were characterised by a significant international expansion and growth through a number of new contracts. In March, Falck acquired the American ambulance company Lifestar, which operates approximately 440 ambulances and other emergency vehicles in seven states on the US east coast. This significantly strengthened Falck’s position in the US ambulance market: the combination of Lifestar and Falck’s existing ownership of Care Ambulance made Falck the third-largest ambulance operator in the US.

26

In March, Falck acquired 63% of the leading South American ambulance and medical company Grupo EMI, which is headquartered in Columbia and has approximately 270 ambulances in Columbia, Uruguay, Venezuela, Ecuador, Panama and El Salvador. Grupo EMI’s activities are based on private subscriptions, and the company serves approximately 750,000 customers with ambulance and medical assistance. Falck also expanded its existing emergency services in Poland, Slovakia, Spain and Sweden. In Poland, Falck won the tender for ambulance-service provision in six regions, where the company now operates 84 ambulances. In Slovakia and Spain operations were expanded by way of new fire-service contracts, and in Sweden Falck gained more new ambulance contracts, e.g. in Stockholm. Assistance Falck’s assistance activities are concentrated in the Nordic countries and were affected by the large amounts of snow and hard frost that hit this region in the first months of the year. In Denmark, cloudbursts and heavy rainfalls in the summer months led to increased assistance activities as customers made use of their subscriptions. In Norway, Finland and partly in Sweden, the severe winter weather resulted in increased revenue, since Falck services in these countries are largely based on pay-per-use. Furthermore, the number of roadside assistances rose in Norway as the result of an


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

REVENUE SPLIT

Training DKK 1,019m: 9% Healthcare DKK 1,112m: 10%

EBITA SPLIT

Training DKK 128m: 13%

Emergency DKK 6,385m: 57%

Healthcare DKK 82m: 8%

Assistance DKK 2,693m: 24%

DKK million Revenue* EBITA* Profit for the year* The Lundbeck Foundation’s share of profit for the year Average number of employees*

Emergency DKK 435m: 45%

Assistance DKK 335m: 34%

2011 2010 10,193 8,367 980 839 516 458 238 25,262

n.a. 19,174

* Falck A/S' figures disclosed for 2010 and 2011. Falck Holding A/S' figures only comprise 6 months activities in 2011.

agreement to supply roadside assistance to the customers of Norway’s largest insurance company. Healthcare In May, Falck’s healthcare division strengthened its position on the Danish market by acquiring the second-largest private supplier of healthcare solutions in Denmark, Healthcare Danmark, which provides interdisciplinary healthcare schemes for 130,000 employees in public and private companies. In addition, the international expansion continued with the acquisition of 75% of the company Starowka, which owns four medical clinics in and around the Polish capital Warsaw. Training Falck’s global training activities, which are focused on safety training of employees in the offshore sector, continued to grow and expand in 2011, with no fewer than 240,000 students being trained. Training in wind-turbine operation was enhanced through the construction of a new training centre in Bremerhaven in Germany. Moreover, a 24-meter-high tower for wind-turbine training was built at Falck’s training centre in Teeside, UK. Falck also strengthened its global market position by acquiring 65% of the company Caspian Safe in Azerbaijan. 2011 results* Falck’s revenue in 2011 was DKK 10,193 million, which corresponds to a total growth rate of 22%. The increase is primarily

attributable to the purchase of rescue-service operations in the US and South America, but the organic growth was also positive, totalling 4%. The operating profit before depreciation and amortisation in relation to acquisitions and special items (EBITA) was DKK 980 million, representing an increase of 17%. The special items amounted to an income of DKK 82 million, which is attributable to a gain on the sale of securities of DKK 242 million (sale of Rural Metro shareholding), the write down of an investment in a subsidiary in Brazil of DKK 142 million, and expenses in relation to the sale of Falck A/S. Income taxes amounted to DKK 184 million against DKK 183 million in 2010, corresponding to an effective tax rate of 26.2%. The fall in the tax rate is primarily attributable to nontaxable extraordinary items as well as higher non-deductible costs of acquisitions. Profit for the year in 2011 amounted to DKK 516 million against DKK 458 million in 2010, representing an increase of 13%. The Lundbeck Foundation’s share of profit for the year before special items amounted to DKK 238 million, of which DKK 101 million relates to the period of 36% ownership and therefore income from associated activities, and DKK 137 million relates to the period of 57% ownership and is included in net profit after minority interests. 27


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Bertil From, CFO

Lundbeckfond Invest manages the Foundation’s portfolio investments and liquidity. Lundbeckfond Invest’s primary purpose is to generate an annual profit from the Foundation’s assets and secure the capital base and sufficient financial reserves, in order to support the development of the subsidiaries and the Foundation’s grant-making activities. As a result, the Foundation’s strategy for Lundbeckfond Invest is that its investments must, at all times, be diversified in terms of both sectors and asset classes. The objective for the weighting of the various asset classes is determined by the Foundation’s Board.

2011 investment strategy The asset allocation in Lundbeckfond Invest changed significantly in 2011. There was a reduction in the proportion of bonds and cash, while the proportion of corporate bonds and equities increased. The reallocation was partly due to the acquisition of Falck, which was funded by liquid funds, and partly due to an active investment decision to increase the share of corporate bonds and equities during the autumn. At the time, equities and corporate bonds had fallen in price, and

were considered to be attractively valued, despite the macroeconomic uncertainty. In 2011, the Lundbeck Foundation reviewed the investment strategy for Lundbeckfond Invest. One result was a decision to outsource less of the asset management of equities and corporate bonds. This follows several years of successful in-house management of corporate bonds and short-term mortgage bonds. The aim is to generate greater value by

ASSET ALLOCATION 2011

2010

Real assets 4% Unlisted equity 9%

Real assets 3% Bonds and cash 38%

Listed equity 36%

Listed equity 30%

Credit including distressed debt and mezzanine 7%

28

Unlisted equity 6%

Credit including distressed debt and mezzanine 7%

Bonds and cash 54%


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

DANISH INTERST RATES

STOCK MARKET INDEX IN DKK

4%

110

3%

100

2%

90

1%

80

0% Jan

Feb

Mar

10 years

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

3 months

70 Jan

Feb US

bringing the investment management more closely into line with the Lundbeck Foundation’s long-term investment horizon, by acting swiftly and by taking full advantage of Lundbeckfond Invest’s special skills. It is also expected to result in cost savings. 2011 market trends 2011 was characterised by economic and financial uncertainty, with sovereign debt crises in Southern Europe and Ireland adding to the turbulence. Growth fell in Europe in particular, but also in the USA. This, along with a growing fear of recession, led to the stock markets falling in value. The greatest falls were in Europe and emerging markets, while the US stock market fared better, with more or less unchanged prices. The credit markets reflected the stock markets, with falls in corporate bonds in Europe and, to a lesser extent, in the United States. These falls were particularly pronounced for low-rated loans and bonds issued by banks. However, interest rates in the countries with the best credit ratings fared really well. The 10-year Danish government bond yield fell below 2%, from 3% at the beginning of the year.

Mar

Apr

Europe

May

Jun

Jul

Aug

Emerging markets

Sep

Oct

Nov

Dec

The world

Bonds and cash contributed positively, as falling interest rates led to capital gains, but the yield was affected by the Foundation already having a short average duration for its bond portfolio at the start of the year. This was because it had been thought that there was a risk of interest rates rising, as longterm rates were already low. Corporate bonds also benefited from the declining government bond rates, but the wider credit spread led to an overall loss. The loss was limited by the fact that further investments were made in the asset class during the autumn, when the debt crisis was at its highest and corporate bond prices were at their lowest. Listed equity generated a loss in line with the markets. Unlisted equity, however, generated a good return. The profit includes substantial returns on buy-out funds, which were helped by some profitable exits, while the portfolio of biotech funds made a negative contribution. Biotech funds were transferred from Lundbeckfond Ventures to Lundbeckfond Invest during the year. Real assets, including the property company Obel-LFI Ejendomme A/S, reported negative returns. The negative returns were mainly due to falling share prices on the portfolio of listed property companies.

Lundbeckfond Invest achieved a return of -1%, corresponding to DKK -66 million, which is acceptable given the economic uncertainty and market conditions.

SUMMARY OF ASSETS AND RETURN

Bonds and cash Credit incl. distressed debt and mezzanine Listed equity Unlisted equity Real assets Lundbeckfond Invest total

Market value 12.31 2011 12.31 2010 DKK m DKK m 3,784 1,330 3,621 835 373 9,943

7,168 925 3,892 784 410 13,179

Return 2011 2010 DKK m DKK m 201 -3 -276 44 -32 -66

293 154 618 88 32 1,185

Weighted return* 2011 2010 % % 4.7 -0.3 -7.6 5.3 -7.9 -0.7

4.3 16.7 18.4 13.9 8.8 9.4

*Return on average holding over the period.

29


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

Mette Kirstine Agger, Managing Partner

Lundbeckfond Ventures is an internationally active “evergreen” life-science venture fund. The evergreen structure allows a flexible investment strategy with a long-term investment perspective. Ventures’ invests broadly in life science, primarily in the development of new medicines and medical technology. It is essential that the projects address clear medical needs and are of high scientific and technical quality. The primary focus is on investment in biotech/pharma companies with early clinical results, and in medtech companies that have achieved regulatory approval or where such approval is underway.

Development 2011 With an investment framework of DKK 1.4 billion until the end of 2014, Lundbeckfond Ventures is one of the major international venture funds and one of the largest in European life sciences. During its first couple of years, Ventures has established a broad network of contacts with other life-science investors and operators in Europe and the USA. As a consequence, 2011 was a highly active year, which saw a significant increase in the number of new investment opportunities. In the course of 2011, Lundbeckfond Ventures invested in three companies, in each case as the lead or co-lead investor. These new companies span a broad range of life sciences. New investments In January 2011, investment was made in Nexstim, Finland. Nexstim develops, manufactures and markets Navigated Brain Stimulation devices for pre-surgical mapping of brain functions e.g. prior to removal of brain tumors and for therapy of diseases of the Central Nervous System. The system is based on transcranial magnetic stimulation. The equipment is now well established in leading international neurosurgical centres. Stimulation of specific areas of the brain has in addition a number of potential therapeutic applications, including treatment of severe depression. Acacia Pharma in the UK was founded by an experienced management team and focuses specifically on developing

30

medicines to treat the side effects of cancer treatment and the complications to which cancer gives rise. For example, at present the company has a new formulation of a known drug in Phase II clinical trials for the new use of treating nausea and vomiting, a side effect that is often associated with both chemical and radiation therapy. The investment in Acacia was made in March 2011. In July 2011, an investment was made in Bonesupport in Sweden. Bonesupport has developed and markets Cerament™, a new bonecement material that stimulates and supports the regeneration of bone and itself remodels into bone. The material can be injected, it is non-toxic to patients and surgical staff, and has a range of future applications, including mixing the material with antibiotics and using it as an alternative to minor bone transplants. Portfolio 2011 As an active investor, Ventures allocates significant resources to its existing portfolio. A number of portfolio companies achieved positive results in 2011, both in development projects and in terms of business goals. Acacia reported positive data from Phase IIa clinical trials of APD209 for the treatment of cancer cachexia, and began Phase II clinical trials of APD515 for the treatment of dry mouth in patients receiving chemotherapy treatment for advanced cancer.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

PORTFOLIO 2011

UK

New drug candidates all in clinical Phase II for treatment of side effects arising from

www.acacia.com

chemotherapy and other forms of cancer treatment.

USA

A disposable insulin pump, Pearl™, which is both user-friendly and competitively

www.asantesolutions.com

priced.

Sweden

Markets Cerament™, a bonecement material that stimulates and supports the re-

www.bonesupport.com

generation of bone tissue and remodels into bone. The material can be injected, is non-toxic and has a range of future potential uses, including the ability to mix it with antibiotics.

dbv

France

New epicutaneous patch primarily for the treatment of food allergies, with a focus on

www.dbv-technologies.com

peanut allergy in the most advanced project. The administration via the skin is par-

technologies

ticularly suitable for the treatment of allergies where other forms of treatment entail the risk of anaphylactic shock. Denmark

Development of potential new drugs for the treatment of cancer, based on inter-

www.epitherapeutics.dk

nationally leading research in epigenetics by Prof. Kristian Helin and his team at the University of Copenhagen.

Finland

New technology that, by means of precise and targeted transcranial magnetic stimu-

www.nexstim.com

lation – and without surgery – can map the brain’s speech and motor centres, e.g. before neurosurgery. The technology also has a number of other potential applications.

Targeted Secretion Inhibitors

UK

Development of new biological medicines based on botulinum toxin analogues for

www.syntaxin.com

the treatment of disease through the targeted inhibition of cellular secretion. The main programme for pain treatment is in Phase II under a license agreement with Allergan.

Denmark

Development of LCP-Tacro™ for immunosuppression in Phase III, specifically targeting

www.veloxis.com

kidney transplants. The first product based on its formulation technology platform MeltDose ® was approved by the FDA in 2008 (LCP, NASDAQOMX).

Targeted Secretion Inhibitors

Veloxis Pharmaceuticals published positive data from a Phase III trial with LCP-Tacro in stable patients who have previously undergone kidney transplants. The results showed, as desired, the same efficiency as for the current product, Prograf. A more detailed analysis revealed a trend toward fewer acute rejections of transplanted kidneys in the group treated with LCP-Tacro. These results form the basis of an application for regulatory approval in Europe. The company also began the final Phase III trial of LCP-Tacro in patients who have recently undergone kidney transplants, and concluded a commercial agreement regarding the already marketed product, Fenoglide.

Ipsen Pharmaceuticals, established a new research collaboration with Syntaxin in recognition of its strong technology platform and patent position. The FDA approved Asante’s insulin pump, Pearl™, and Nexstim published a series of results from the use of its equipment for planning surgical interventions in the brain. Financial performance Lundbeckfond Ventures made a loss of DKK 70 million in 2011, compared to a loss of DKK 50 million in 2010, mainly due to Veloxis’ share price.

The development of a new treatment for peanut allergy went a step further when DBV Technologies completed a Phase Ib trial with their innovative patch technology in US, which showed that the product is well tolerated and without serious side effects. The company was granted fast-track status by the FDA because of the obvious medical need. Syntaxin’s partner Allergan began Phase II clinical trials with AGN-214868 for pain and overactive bladder, respectively. Another major industry player in botulinum toxin-based drugs,

31


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

SOCIAL RESPONSIBILITY, RISK MANAGEMENT AND FUTURE EXPECTATIONS Social responsibility The Lundbeck Foundation through its annual grants to research and its subsidiaries has a significant position in Danish research, education and business. This manifests itself as follows: • The Lundbeck Foundation owns and supports the develop ment of H. Lundbeck, ALK and Falck, whose products and services contribute to human health, well-being and safety. The Foundation's ownership of these companies secures their ties with Denmark. • The Lundbeck Foundation grants large sums for scientific research of high international standard with ties to Denmark, such as research within the biomedical and natural sciences, for the benefit of the Danish society as a whole. • Making risk-bearing venture investments both nationally and internationally in the life sciences. Policies and codes of conduct for H. Lundbeck, ALK and Falck's social responsibility are determined by the respective companies' boards, on which the Lundbeck Foundation is represented. For further description, please refer to the subsidiaries' annual reports for 2011 and their respective websites. In addition, the Lundbeck Foundation has entered UN Global Compact. Business and financial risks The Lundbeck Foundation Group seeks to ensure a reasonable balance between risk exposure and value generation. The main risks are the business and financial risks associated with the operations of the subsidiaries H. Lundbeck, ALK and Falck, Lundbeckfond Invest and Lundbeckfond Ventures. The Foundation's risk management is focused on its portfolio investments. The market risk on portfolio investments is managed by limiting maximum exposure to individual asset classes and underlying assets. The limitations are set by the Foundation's investment policy, which is adopted by the Board. The investment policy also limits the investment levels that can be decided by the management, the Investment Committee and the Board. Weekly portfolio reports are submitted to the management. Regarding risk management in H. Lundbeck, ALK and Falck, please refer to their annual reports for 2011, since these companies individually set policies and procedures regarding risk management. In addition, the Lundbeck Foundation continuously monitors the development in the subsidiaries.

32

Events after the end of the financial year There have been no significant events since the end of the financial year. Future expectations The Lundbeck Foundation Group's results will depend on how the business activities of H. Lundbeck, ALK and Falck develops and on returns from the portfolio and venture investments. For a more detailed description of the expected development of the subsidiaries, please refer to www.lundbeck.com, www.alk-abello.com and www.falck.com. In 2012, the Lundbeck Foundation has a target of making regular grants worth DKK 300 million and up to DKK 200 million to strategic initiatives.


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

CONSOLIDATED FINANCIAL STATEMENTS

CONTENTS Income statement for the period 1 January – 31 December Statement of comprehensive income for the period 1 January – 31 December Balance sheet at 31 December Management statement and Independent auditor's report Cash flow statement for the period 1 January – 31 December Statement of changes in equity for the period 1 January – 31 December Notes 1. Accounting policies 2. Revenue 3. Staff costs 4. Depreciation, amortisation and impairment 5. Fees to auditors appointed at the general meeting 6. Special items 7. Net financial items 8. Tax on profit for the year 9. Grants for the year 10. Intangible assets 11. Property, plant and equipment 12. Investments in associates 13. Financial assets and financial risks 14. Deferred tax 15. Inventories 16. Trade receivables and other receivables 17. Income tax 18. Cash resources 19. Assets held for sale 20. Capital base 21. Other reserves 22. Minority interests 23. Pensions and similar obligations 24. Liabilities relating to acquisitions and minority interests 25. Other provisions 26. Mortgage, bank, leasing and repo debt 27. Adjustments 28. Working capital changes 29. Business combinations 30. Financial risks and financial instruments 31. Contractual obligations 32. Guarantees and contingent liabilities 33. Related parties 34. Events after the balance sheet date Group overview

CONSOLIDATED FINANCIAL STATEMENTS

34 35 36 38 40 41

41 52 52 56 57 57 57 58 59 60 61 62 63 65 67 67 68 68 69 69 70 70 70 73 74 74 76 76 76 79 85 86 88 88 89

33


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

INCOME STATEMENT FOR THE PERIOD 1 JANUARY – 31 DECEMBER

2011 2010 2009 Note DKKm DKKm DKKm Revenue 2 23,602 16,927 15,594 Cost of sales 3, 4 (7,568) (3,611) (3,242) Gross profit 16,034 13,316 12,352 Research and development costs 3, 4 (3,775) (3,411) (3,545) Distribution costs 3, 4 (5,074) (4,239) (3,846) Administrative expenses 3, 4, 5 (3,020) (2,153) (2,083) Profit from operations before special items (EBIT) 4,165 3,513 2,878 Special items 6 (362) - Profit from operations 3,803 3,513 2,878 Income from investments in associates 12 100 - Financial income 7 813 1,643 1,897 Financial expenses 7 (1,187) (560) (596) Profit before tax 3,529 4,596 4,179 Tax on profit for the year 8 (1,100) (899) (735) Profit for the year 2,429 3,697 3,444

Minority interests’ share of profit for the year (815) (817) (688) Lundbeck Foundation's share of profit for the year 1,614 2,880 2,756 Grants for the year, net 9 (498) (383) (340) Lundbeck Foundation's profit for the year after grants 1,116 2,497 2,416

34

Lundbeck Foundation's share of profit for the year Special items after tax Minority interests’ share of special items after tax Lundbeck Foundation's share of profit for the year before special items

CONSOLIDATED FINANCIAL STATEMENTS

1,614 302 (101) 1,815

2,880 - - 2,880

2,756 2,756


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

STATEMENT OF COMPREHENSIVE INCOME FOR THE PERIOD 1 JANUARY – 31 DECEMBER

2011 2010 2009 Note DKKm DKKm DKKm

Profit for the year 2,429 3,697 3,444 Currency translation, foreign subsidiaries 105 328 (36) Currency translation concerning additions to net investments in foreign subsidiaries 115 240 (444) Realised exchange gains/losses concerning additions to net investments in foreign subsidiaries 20 - Adjustment, deferred exchange gains/losses, hedging 64 (214) 8 Exchange gains/losses, hedging (transferred to the hedged items) (127) 163 (1) Exchange gains/losses, trading (transferred from hedging) - 1 22 Value adjustment of interest hedging instruments (56) - Repayment of interest hedging instruments 15 - Accumulated exchange loss on divestment of investments in associates - 2 Other equity entries concerning associates (18) (1) - Fair value adjustment of available-for-sale financial assets 21 (6) (4) 27 Tax on other comprehensive income 8 (19) (51) 93 Other comprehensive income 93 464 (331) Comprehensive income 2,522 4,161 3,113 Minority interests’ share of comprehensive income for the year 22 (843) (965) (586) Lundbeck Foundation's share of comprehensive income 1,679 3,196 2,527 Currency translation of foreign subsidiaries and currency translation concerning additions to net investments in foreign subsidiaries and tax related to these items, totalling DKK 197 million (2010: DKK 505 million), is recognised in the currency translation reserve in equity. Other items and tax related to such items are recognised in reserve for hedging transactions and reserve for fair value adjustments of available-for-sale financial assets, respectively, at a loss of DKK 77 million (2010: DKK 50 million) and DKK 6 million (2010: DKK 4 million) and recognised under retained earnings in equity in the amount of DKK 49 million (2010: DKK 135 million).

CONSOLIDATED FINANCIAL STATEMENTS

35


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

BALANCE SHEET AT 31 DECEMBER, ASSETS

2011 2010 2009 Note DKKm DKKm DKKm

Goodwill 10 9,733 4,298 3,987 Contractual customer relationships etc. 10 3,005 - Product rights 10 4,270 3,591 3,552 Patent and license rights 10 192 323 252 Other intangible assets 10 386 379 400 Projects in progress 10 64 127 81 Intangible assets 10 17,650 8,718 8,272 Land and buildings 11 3,180 2,785 2,709 Plant and machinery 11 581 543 613 Other fixtures and fittings, tools and equipment 11 1,094 303 351 Leasehold improvements 11 58 - Prepayments and other assets under construction 11 788 637 496 Property, plant and equipment 1 1 5,701 4,268 4,169 Investments in associates 12 15 - Financial assets at fair value through profit or loss 13 9,784 10,002 10,522 Available-for-sale financial assets 13 89 21 26 Other receivables 13 87 85 67 Deferred tax 14 483 178 181 Financial assets 10,458 10,286 10,796 Non-current assets 33,809 23,272 23,237

Inventories 15 1,985 1,801 1,781 Trade receivables 16 3,995 2,366 2,190 Other receivables 16 716 469 492 Receivables from associates 55 - Income tax 17 134 261 218 Prepayments 367 277 235 Receivables 5,267 3,373 3,135 Securities 18 2,315 496 1,109 Cash 18 3,985 5,790 2,847 Assets held for sale 19 98 - Current assets 13,650 11,460 8,872 Assets 47,459 34,732 32,109

36

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

BALANCE SHEET AT 31 DECEMBER, EQUITY AND LIABILITIES

2011 2010 2009 Note DKKm DKKm DKKm

Capital base 20 2,225 2,050 1,900 Other reserves 21 (180) (294) Retained earnings 20,506 19,640 16,674 Lundbeck Foundation's share of equity 22,551 21,396 18,574 Minority interests' share of equity 22 3,781 4,571 3,825 Total equity 26,332 25,967 22,399 Payable grants 389 308 326 Pensions and similar obligations 23 342 316 285 Deferred tax 14 1,871 601 785 Liabilities relating to acquisitions and minority interests 24 512 - Other provisions 25 191 280 277 Mortgage debt 26 2,262 1,885 1,884 Bank and leasing debt 26 6,143 10 763 Employee bonds and other debt 76 60 65 Non-current liabilities 11,786 3,460 4,385 Payable grants 530 416 297 Pensions and similar obligations 23 19 12 15 Liabilities relating to acquisitions and minority interests 24 43 - Employee bonds 13 - Other provisions 25 217 216 186 Mortgage debt 26 1 1 1 Bank and leasing debt 26 283 10 808 Repo debt 26 97 297 Trade payables 2,280 1,377 1,131 Income tax 17 244 137 156 Other payables 3,877 2,322 2,038 Prepayments 2, 32 1,639 517 693 Current liabilities 9,243 5,305 5,325 Liabilities relating to assets held for sale 19 98 - -

Liabilities 21,127 8,765 9,710 Equity and liabilities 47,459 34,732 32,109

CONSOLIDATED FINANCIAL STATEMENTS

37


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

MANAGEMENT STATEMENT

The Board of Directors and the Executive Management have today presented the annual report of the Lundbeck Foundation for the financial year ended 31 December 2011. The consolidated financial statements have been prepared in accordance with International Financial Reporting Standards as adopted by the EU and Danish disclosure requirements for annual reports, and the financial statements of the Foundation have been prepared in accordance with the Danish Financial Statements Act. We consider the accounting policies used to be appropriate. Accordingly, the consolidated financial statements and the financial statement of the parent foundation give a true and

fair view of the Group’s and the Foundation’s assets, liabilities and financial position at 31 December 2011, and of the Group’s and the Foundation’s activities and the Group’s cash flows for the financial year 1 January – 31 December 2011. We believe that the management’s review includes a fair review of developments in the Group’s and the Foundation’s activities and finances, results for the year and the Group’s and the Foundation’s financial position in general as well as a fair description of the principal risks and uncertainties to which the Group and the Foundation are exposed. We recommend that the annual report be approved at the annual meeting.

Copenhagen, 2 May 2012

Executive Management Christian Dyvig

Board of Directors

38

Mikael Rørth Chairman

Jørgen Huno Rasmussen Deputy Chairman

Thorleif Krarup

Povl Krogsgaard-Larsen

Gunhild Waldemar

Jes Østergaard

Kim Klitgaard Elected by the employees

Ken Liljegren Elected by the employees

Peter Adler Würtzen Elected by the employees


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

INDEPENDENT AUDITOR’S REPORT

To the Board of Directors of the Lundbeck Foundation Report on the consolidated financial statements and the Foundation's financial statements We have audited the consolidated financial statements and the Lundbeck Foundation's financial statements for the financial year 1 January – 31 December 2011, which comprise the income statement, balance sheet, statement of changes in equity and notes, including the accounting policies, for the Group as well as the Foundation, and the statement of comprehensive income and the cash flow statement for the Group. The consolidated financial statements are prepared in accordance with International Financial Reporting Standards as adopted by the EU and Danish disclosure requirements for annual reports, and the Foundation's financial statements are prepared in accordance with the Danish Financial Statements Act. Managements’ responsibility for the consolidated financial statements and the Foundation's financial statements Management is responsible for the preparation of consolidated financial statements that give a true and fair view in accordance with International Financial Reporting Standards as adopted by the EU and Danish disclosure requirements for annual reports as well as the preparation of financial statements of the Foundation that give a true and fair view in accordance with the Danish Financial Statements Act, and for such internal control as Management determines is necessary to enable the preparation of consolidated financial statements and financial statements of the Foundation that are free from material misstatement, whether due to fraud or error. Auditor's responsibility Our responsibility is to express an opinion on the consolidated financial statements and the Foundation's financial statements based on our audit. We conducted our audit in accordance with International Standards on Auditing and additional requirements under Danish audit regulation. This requires that we comply with ethical requirements and plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements and the Foundation's financial statements are free from material misstatement. An audit involves performing procedures to obtain audit evidence about the amounts and disclosures in the consolidated financial statements and the Foundation's financial statements. The procedures selected depend on the auditor’s judgement, including the assessment of the risks of material misstatement of the consolidated financial statements and the Foundation's financial statements, whether due to fraud or er-

ror. In making those risk assessments, the auditor considers internal control relevant to the preparation of consolidated financial statements and the Foundation's financial statements that give a true and fair view in order to design procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the entity's internal control. An audit also includes evaluating the appropriateness of accounting policies used and the reasonableness of accounting estimates made by Management, as well as the overall presentation of the consolidated financial statements and the Foundation's financial statements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our audit opinion. Our audit has not resulted in any qualification. Opinion In our opinion, the consolidated financial statements and the Foundation's financial statements give a true and fair view of the Group’s assets, liabilities and financial position at 31 December 2011 and of the results of the Group’s operations and cash flows for the financial year 1 January to 31 December 2011 in accordance with the International Financial Reporting Standards as adopted by the EU and Danish disclosure requirements for annual reports. Further, in our opinion, the Foundation's financial statements give a true and fair view of the Foundation’s assets, liabilities and financial position at 31 December 2011 and of the results of the Foundation’s operations for the financial year 1 January – 31 December 2011 in accordance with the Danish Financial Statements Act. Statement on the management review Pursuant to the Danish Financial Statements Act, we have read the management review. We have not performed any further procedures in addition to the audit of the consolidated financial statements and the Foundation's statements. On this basis, it is our opinion that the information provided in the management review is consistent with the consolidated financial statements and the Foundation's financial statements. Copenhagen, 2 May 2012 Deloitte Statsautoriseret Revisionspartnerselskab

Anders Dons State Authorised Public Accountant

Martin Faarborg State Authorised Public Accountant

39


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

CASH FLOW STATEMENT FOR THE PERIOD 1 JANUARY – 31 DECEMBER

2011 2010 2009 Note DKKm DKKm DKKm Profit from operations before special items (EBIT) 4,165 3,513 2,878 Special items (51) - Adjustments 27 1,489 1,193 929 Working capital changes 28 23 106 323 Cash generated from operations 5,626 4,812 4,130 Financial receipts Dividend received Financial payments Income tax paid for the year 17 Income tax paid/received regarding previous years 17 Authorised grants paid Cash flows from operating activities

258 113 (317) (989) 80 (304) 4,467

464 91 (313) (1,177) (51) (283) 3,543

455 96 (250) (767) 24 (281) 3,407

Acquisition of companies 29 Investments in intangible assets Investments in property, plant and equipment Disposal of property, plant and equipment Investments in other financial assets at fair value through profit or loss Sale of other financial assets at fair value through profit or loss Change in other financial assets Cash flows from investing activities

(4,537) (1,005) (558) 26

(178) (468) (521) 3

(5,133) (1,010) (461) 4

(8,020)

(6,042)

(6,293)

6,084 (11) (8,021)

8,067 (5) 856

5,916 (18) (6,995)

Loan proceeds Repayment of loans Change in financial liabilities Buyback of shares from minority interests Employee bonds Dividend paid to minority interests 22 Cash flows from financing activities

6,305 (4,222) - (76) (9) (252) 1,746

297 (1,560) 2 (24) - (211) (1,496)

2,507 (999) (10) (11) 8 (166) 1,329

Change in cash Cash at 1 January Unrealised exchange adjustments for the year Cash at 31 December

(1,808) 5,790 3 3,985

2,903 2,847 40 5,790

(2,259) 5,092 14 2,847

40

18

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

STATEMENT OF CHANGES IN EQUITY FOR THE PERIOD 1 JANUARY - 31 DECEMBER - NOTE 1

Lundbeck Minority

Foundation's interests'

Capital

Other

Retained

share of

share of

Total

base reserves earnings equity equity equity DKKm DKKm DKKm DKKm DKKm DKKm

Equity at 1 January 2011

2,050

Profit for the year

Other comprehensive income

Comprehensive income

-

(294)

19,640

21,396

4,571

25,967 2,429

1,614

1,614

815

114

(49)

65

28

93

114

1,565

1,679

843

2,522

Grants authorised during the year, net

(498)

(498)

(498)

Minority interests' share of dividends

-

(252)

(252)

Buyback of shares from minority interests

(29)

(29)

(52)

(81)

Minority interests in Falck acquisition

-

(1,329)

(1,329)

Increase in minority interests

1

1

2

3

for acquisition of minority interests

(19)

(19)

(14)

(33)

Incentive programmes

21

21

-

-

(524)

(524)

175

-

(175)

-

-

-

Adjustment of provision

Other transactions Increase of capital base

12 (1,633)

33 (2,157)

Equity at 31 December 2011

2,225

(180)

20,506

22,551

3,781

26,332

Equity at 1 January 2010

1,900

(745)

17,419

18,574

3,825

22,399 3,697

Profit for the year

Other comprehensive income

Comprehensive income

-

2,880

2,880

817

451

(135)

316

148

464

451

2,745

3,196

965

4,161

Grants authorised during the year, net

(383)

(383)

(383)

Minority interests' share of dividends

-

(211)

(211)

Buyback of shares from minority interests

(7)

(7)

(18)

(25)

Incentive programmes

16

16

10

26

-

-

(374)

(374)

(219)

(593)

150

-

(150)

-

-

-

19,640

21,396

4,571

25,967

Other transactions Increase of capital base Equity at 31 December 2010

2,050

(294)

1. ACCOUNTING POLICIES

The consolidated financial statements have been prepared in accordance

IFRS 1, First-time adoption of IFRS, has been applied for the presentation of

with International Financial Reporting Standards (IFRS) as adopted by

consolidated financial statements according to IFRS. In accordance with this

the EU and the Danish Statutory Order on Adoption of IFRS issued pur-

standard, an IFRS opening balance sheet has been prepared as at 1 January

suant to the Danish Financial Statements Act.

2010, and like the accounting figures for 2011 and the comparative figures

for 2010 this has been prepared in accordance with the standards (IFRS/

The consolidated financial statements for 2011 are the first consolidated

IAS) and interpretations (IFRIC/SIC) in force at the balance sheet date of the

financial statements prepared for the Lundbeck Foundation. The Lundbeck

transition year, i.e. at 31 December 2011. The Group has applied the exemp-

Foundation has not previously prepared consolidated financial statements,

tion clause, under which there is no requirement for a 5-year overview of

as these were prepared by the wholly owned holding and investment com-

changes in pension obligations. The information has therefore been provided

pany Lundbeckfond Invest A/S.

prospectively from 1 January 2010.

The consolidated financial statements are presented in Danish kroner (DKK), which also is the functional currency of the Lundbeck Foundation.

CONSOLIDATED FINANCIAL STATEMENTS

41


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

The annual report has been prepared under the historical cost convention,

• Sales of escitalopram are invoiced at the agreed price, but only a propor-

except that the following assets and liabilities are measured at fair value:

tion (the minimum price) of the invoiced price is recognised as income at

derivative financial instruments and financial instruments at fair value.

the time of delivery. • The difference between the invoiced price and the minimum price of

The consolidated financial statements are presented in accordance with the

Forest's inventories is recognised in the balance sheet as prepayments.

new and revised standards (IFRS/IAS) and interpretations (IFRIC) which

• After the end of each quarter, the final settlement price is calculated. The

apply for the financial year.

difference between the final calculated settlement price and the invoiced price is recognised as income and settled with Forest, and the difference between the invoiced price and the minimum price recognised in the ba-

Future IFRS changes

lance sheet as prepayment at the time of delivery is recognised as income.

At the date of the publication of these consolidated financial statements,

In connection with a potential launch of generic escitalopram in the USA,

a number of new and amended standards and interpretations have not yet

the agreement allows Forest to convert escitalopram inventories into generic

entered into force or have not yet been adopted by the EU. Therefore, they

escitalopram. In connection with a conversion of escitalopram inventories

are not included in the consolidated financial statements. None of these

into generic escitalopram, the minimum price will be adjusted by any repay-

changes are expected to have a material impact on future consolidated

ment to Forest of part of the recognised minimum payment. This adjustment

financial statements.

will be expensed in the financial statements.

The future amendments to IAS 19 Employee benefits entail that actuarial

License income and income from research collaborations

gains and losses must be recognised in the statement of comprehensive

License income and royalties from outlicensed products and non-refundable

income and that the corridor approach is no longer permitted. The Lund-

downpayments and milestone payments relating to research collaborations

beck Foundation currently recognises all costs associated with defined

totalled DKK 1,088 million in 2011 (DKK 657 million in 2010, which is recog-

benefit pension plans under staff costs in the income statement and does

nised in the income statement under revenue when the following criteria

not apply the corridor approach. Apart from the fact that actuarial gains and

have been met:

losses must henceforth be recognised in the statement of comprehensive

• The payment relates to research results already obtained.

income, the amendments are not expected to materially affect recognition

• The most significant risks and benefits associated with the asset sold are

or measurement in future consolidated financial statements.

transferred to the buyer. • The Group does not retain management control of the asset sold. • Revenue from the individual payments in an overall agreement can be

Accounting policies and estimates critical to financial reporting

clearly separated and calculated reliably at fair value. • It is probable that the Group will receive payment for the asset sold. • There are no further delivery obligations for the Group concerning the

In the preparation of the consolidated financial statements in accordance

asset sold.

with IFRS and generally accepted accounting principles, it is necessary for Management to make certain estimates and assumptions as not all accoun-

Research and development costs

ting items and accruals can be calculated with certainty.

Research and development costs totalled DKK 3,775 million in 2011 (DKK 3,411 million in 2010). Development costs are capitalised if the criteria for

Management’s estimates are based on historical data, recent information

such capitalisation are deemed to have been met and it is found to be pro-

available at the time of presentation of the financial statements and other

bable that future earnings will cover the development costs. Due to a very

assumptions considered reasonable under the given circumstances. The

long development period and significant uncertainty in relation to the deve-

actual outcome may differ from these estimates.

lopment of new products, in the opinion of the Group, development costs should not normally be capitalised in the balance sheet until the develop-

The estimates are made by the management of the Lundbeck Foundation,

ment of the product has been completed and all the necessary public reg-

the H. Lundbeck Group, the ALK Group and the Falck Group, respectively.

istration and marketing approvals have been obtained. Development costs relating to individual minor development projects running for short-term

It is believed that the following accounting policies and accounting estimates

periods and subject to limited risk are capitalised under other intangible

are critical to the Group's financial reporting for 2011.

assets. Otherwise, development costs will be recognised in the income statement as they are incurred.

Income from Forest Income from Forest from the sale of citalopram and escitalopram amounted

Intangible assets

to DKK 2,535 million in 2011 (DKK 2,443 million in 2010). The invoiced price is

Goodwill and product rights and contractual customer relationships etc.

agreed between Forest and H. Lundbeck at the beginning of each calendar

represent a significant part of the Group's total assets, amounting to DKK

year. The price is calculated on the basis of expectations for the coming

17,008 million in 2011 (DKK 7,889 million in 2010). The majority of the value of

year's development in the components included in the royalty calculation.

these items arose through the acquisition of companies. In connection with

These components are: Forest’s net selling prices, quantities used in sold

acquisitions, the individual assets and liabilities are re-assessed to ensure

products, quantities used in samples, quantities wasted during processing,

that both recognised and unrecognised values are measured at fair value.

and the various dosage levels of the finished goods. Income from sales of

Especially for intangible assets for which there is often no active market,

escitalopram to Forest is recognised as follows:

the calculation of fair value may involve uncertainty. Intangible assets with indefinite lives and intangible assets in progress are tested for impairment at

42

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

least once a year or if there is evidence of impairment. Contractual customer

Amortisation and depreciation periods and scrap values

relationships etc. identified at acquisitions were primarily acquired with a

In the determination of the carrying amount of intangible assets and

view to further developing the acquired business areas and markets and

property, plant and equipment, estimates are required of the estimated

establishing positions in new markets. As a result, a large part of the pur-

economic lives of the assets and of scrap values.

chase prices has been allocated to goodwill. The value in use of the product rights is calculated by discounting the estimate made by Management over the expected cash flows during a budget period of at least five years with

Recognition and measurement

due consideration to patent expiry. For the calculation of the value in use of the assets, the Group uses different discount factors depending on the

Assets are recognised in the balance sheet when it is probable that future

individual areas of activity and Management's expectations for growth and

economic benefits will flow to the Group and the value of the asset can be

terminal value. These factors are crucial for the assessment of any impair-

measured reliably. Liabilities are recognised in the balance sheet if they are

ment and thus for the final calculation of the fair value of intangible assets.

probable and can be measured reliably.

It is a precondition for the retention of the value of the Group's rights that

On initial recognition, assets and liabilities are measured at cost or fair value.

such rights are respected. It is the Group's policy to defend these rights

Subsequently, assets and liabilities are measured as described below for

wherever they may be violated.

each individual item.

Financial assets

Certain financial assets and financial liabilities are measured at amortised

Financial assets include investments in listed and unlisted equity instruments

cost, implying the recognition of a constant effective rate of interest to

and securities, including life science investments recognised at their fair

maturity. Amortised cost is stated as original cost less any principal pay-

value. Investments in unlisted equity instruments and securities at the end of

ments and plus/less the accumulated amortisation of any difference

2011 amounted to DKK 1,294 million (DKK 1,136 million in 2010).

between cost and the nominal amount. Recognition and measurement take into consideration gains, losses and risks that arise before the time of

The assessment of fair value of these investments is subject to considerable

presentation of the consolidated financial statements and that confirm or

risk. This applies especially to life science investments because the value of

invalidate matters existing at the balance sheet date.

these businesses is linked to the company's often long-term investment in Income is recognised in the income statement as earned and includes value

the development of new pharmaceuticals and technologies.

adjustments of financial assets and financial liabilities measured at fair value Management estimates the fair value of unlisted investments in accordance

or amortised cost. In addition, expenses incurred to generate the income for

with International Private Equity and Venture Capital Valuation Guidelines.

the year are recognised, including depreciation, amortisation, impairment

i.e. on the basis of relevant valuation methods based on comparable transac-

losses and provisions as well as reversals of amounts previously recognised

tions on market conditions, capital increases and the like. If the fair value

in the income statement as a result of changed accounting estimates.

cannot be determined with sufficient reliability, the investments in question are recognised at cost less any impairment. The Group assesses at each balance sheet date whether there is objective evidence that an investment

Consolidated financial statements

or a group of investments is impaired. An impairment loss is recorded if the Group assesses that lack of compliance with business plans affect the

The consolidated financial statements include the Lundbeck Foundation and

calculation of fair value or if subsequent capital injections are made at lower

subsidiaries controlled by the Foundation. Control is achieved where the

prices.

Foundation directly or indirectly holds more than 50% of the voting rights or is otherwise able to exercise or actually exercises control.

Purchase price allocation in business combinations In connection with allocation of purchase price in business combinations,

Companies in which the Group holds between 20% and 50% of the voting

calculations are made of fair value of acquired assets and liabilities. Since

rights and/or exercises significant influence but not control are regarded as

such calculations are based on expected future cash flows relating to the

associates. Unrealised gains on transactions with associates are eliminated in

acquired assets and liabilities, there is an inherent uncertainty in respect of

proportion to the Group’s share of the enterprise.

whether such cash flows will materialise as expected. In accordance with IFRS 3, the purchase price allocations in business combinations may be

Associates included in the Group's documented investment strategy are

adjusted for up to 12 months from the date of acquisition.

recognised as financial assets measured at fair value through profit or loss.

Provisions for acquisition of minorities

Basis of consolidation

Provisions for acquisition of minorities amounted to DKK 555 million at 31

The consolidated financial statements are prepared on the basis of the

December 2011. When calculating the fair value of issued put options which

financial statements of the Foundation and the subsidiaries, which are all

commit the Group to acquire minority interests in subsidiaries, the Manage-

prepared in accordance with the Group's accounting policies.

ment applies estimates of, e.g. the subsidiaries' future financial performance, the likelihood of option holders exercising their selling right and the time

The consolidated financial statements are prepared by adding together uni-

of exercise. These factors are of material importance to the fair value calcu-

form items and eliminating intra-group income and expenses, investments,

lation, which is therefore subject to uncertainty.

balances and dividends as well as realised and unrealised gains and losses on transactions between the consolidated companies. Account is taken of the tax effect of these eliminations.

CONSOLIDATED FINANCIAL STATEMENTS

43


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

Financial statement items of subsidiaries are fully consolidated. Profit for the

Minority interests

year and equity attributable to minority interests in subsidiaries that are not fully controlled are included in the consolidated profit and equity and stated

On initial recognition, minority interests are either recognised at fair value

as separate line items.

(including the fair value of goodwill related to minority interests in the acquired company) or at the minority interests' share of the acquired com-

Business combinations

pany's identifiable assets, liabilities and contingent liabilities measured at fair

Newly acquired companies are recognised in the consolidated financial

value (excluding the fair value of goodwill related to minority interests in the

statements from the date of acquisition. Companies sold or discontinued are

acquired company). The measurement basis for minority interests is selected

recognised in the consolidated income statement up to the time of sale or

for each individual transaction.

discontinuance. Expected costs related to divestment or discontinuance are included in the calculation of gains or losses.

Acquisition and divestment of minority interests Acquired businesses are accounted for using the purchase method of accounting, according to which the identifiable assets, liabilities and contin-

Increases and reductions of minority interests are treated for accounting

gent liabilities of the acquired companies are measured at fair value at the

purposes as transactions with owners, in their capacity as owners. As a

time of acquisition. Account is taken of the tax effect of the revaluations

result, any differences between adjustment to the carrying amount of mino-

made. The cost of a business is generally the fair value of the consideration

rity interests and the fair value of the consideration received or paid are

paid. If the final determination of the consideration is contingent on one or

recognised directly in equity.

more future events, the value thereof will be recognised at fair value at the date of acquisition. Changes to contingent considerations are recognised

When put options are issued as part of the consideration for business com-

in the income statement. Put options issued in connection with acquisitions

binations, the minority interests receiving put options are considered to have

and the value of which is contingent on future events will be recognised as

been redeemed on the acquisition date. The minority interests are eliminated

part of the consideration at the date of acquisition. The put options issued

and a debt obligation is recognised at fair value on initial recognition. Fair

are subsequently measured at fair value. Any changes to the fair value of

value is calculated as the present value of the exercise price of the option.

issued put options after initial recognition are recognised in equity. Costs

Subsequent measurements are made at amortised cost with amortisation

directly attributable to the business combination are recognised in the

and value changes to equity being recognised on an ongoing basis.

income statement as incurred. Adjustments of commitments in connection with conditional consideration or issued put options the value of which

Issued put options relating to business combinations with an acquisition

is contingent on future events concerning business combinations with an

date before 1 January 2010 will still be recognised in accordance with IFRS 3

acquisition date before 1 January 2010 will still be recognised in accordance

(2004). Accordingly, the subsequent measurement will be made at amor-

with IFRS 3 (2004). Accordingly, the adjustments are recognised in goodwill

tised cost with ongoing recognition of interest expenses in the income

until the conditions have been met or the issued put options exercised.

statement and value changes in goodwill. Any subsequent dividend payments to option holders are recognised as a financial expense in the income

Positive differences (goodwill) between the cost of the acquired business

statement in the cases where the option price is independent of dividend

and the fair value of the acquired identifiable assets, liabilities and contin-

payments. Dividend payments are included in the determination of the cost

gent liabilities are recognised under intangible assets. Negative differences

of the put options in cases where the option price is adjusted for dividend

(negative goodwill) between the cost of the acquired business and the fair

payments received.

value of the acquired identifiable assets, liabilities and contingent liabilities are recognised in the income statement at the time of acquisition. Goodwill arising from acquired businesses is adjusted within a maximum period of 12

Translation of foreign currency

months from the acquisition if additional information about the fair value at the time of acquisition of assets, liabilities and contingent liabilities acquired

A functional currency is determined for each of the reporting enterprises of

is obtained after the acquisition. However, goodwill will not be recognised by

the Group. The functional currency is the currency in the primary economic

an amount exceeding the expectations of future income from the acquiree.

environment in which the reporting entity operates. Transactions in currencies other than the functional currency are transactions in foreign currencies.

Goodwill and fair value adjustments in connection with the acquisition of independent foreign entities (subsidiaries or associates) are accounted for

On initial recognition, transactions denominated in foreign currencies are

as assets and liabilities in the acquiree and translated at the exchange rate at

translated at standard rates which approximate the actual exchange rates

the balance sheet date.

at the transaction date. Exchange differences arising between the exchange rate at the transaction date and the exchange rate at the date of payment

Gains or losses on disposal or discontinuance of subsidiaries and associates

are recognised in the income statement as net financials except in case of

Gains or losses on the disposal or discontinuance of subsidiaries and associ-

hedge accounting. In case of hedge accounting, such differences are recog-

ates are calculated as the difference between the selling price or the discon-

nised in the same item as the hedged item.

tinuance amount and the carrying amount of net assets at the time of sale as well as anticipated costs relating to sale or discontinuance. The resulting

Receivables, payables and other monetary items denominated in foreign

gain or loss is recognised in the income statement together with accumula-

currencies that have not been settled at the balance sheet date are trans-

ted currency translation adjustments previously recognised in other compre-

lated at the exchange rates at the balance sheet date. The difference

hensive income. A proportional capital reduction does not result in recycling

between the exchange rates at the balance sheet date and the rates at the

of accumulated exchange rate adjustments through profit or loss.

time the receivable or payable is created or recognised in the latest consoli-

44

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

dated financial statements is recognised in the income statement under net

financial assets for which the fair value is measured on the basis of valuation

financials in respect of unhedged items and under the same item for hedged

techniques which include inputs not based on observable market data.

items. On recognition of foreign subsidiaries having a functional currency different

Income statement

from that used by the Foundation, non-monetary as well as monetary items are translated at the exchange rates at the balance sheet date. Exchange

Revenue: Pharmaceuticals for the treatment of brain disorders and allergy

differences arising from the translation of both the balance sheets and the

Revenue comprises invoiced sales for the year less returned goods and

income statements of the foreign subsidiaries are recognised in the Group's

revenue-based taxes consisting mainly of value added taxes and foreign

statement of comprehensive income under other comprehensive income.

revenue-based drug taxes.

Foreign exchange adjustment of receivables from or debt to subsidiaries

Sales subject to a price adjustment clause are included in revenue at the

which are considered part of the Foundation's overall investment in the sub-

time of delivery at the minimum price. The balance of the invoiced price is

sidiary in question is recognised in the Group's statement of comprehensive

recognised in the balance sheet as a prepayment and is subsequently

income under other comprehensive income.

included in revenue when the price has been finally determined. The price is finally determined as the product is resold by the customer.

On recognition of foreign associates having a functional currency different from that used by the Foundation, assets and liabilities are translated at the

Moreover, revenue includes license income and royalties from outlicensed

exchange rates at the balance sheet date, while the income statement is

products as well as non-refundable downpayments and milestone payments

translated at average exchange rates for the year. Exchange differences aris-

relating to research and development collaborations.

ing from the translation of foreign associates are recognised in the Group's statement of comprehensive income under other comprehensive income.

In addition, income from the reduction of investments in research enterprises considered to represent the sale of research results is recognised as revenue.

Financial instruments

See Accounting policies and estimates critical to financial reporting for a description of the accounting treatment of income from Forest and of

Forward exchange contracts and other derivatives are initially recognised

license income and income from research collaborations.

in the balance sheet at fair value on the value date and are subsequently remeasured at fair value at the balance sheet date. Positive and negative fair

Revenue: Emergency, Assistance, Healthcare and Training sectors

values are included in other receivables and other payables respectively.

Revenue represents the value of services and goods delivered and invoiced subscriptions attributable to the financial period, and is recognised in the

Changes in the fair value of derivatives classified as hedging instruments

income statement if delivery and transfer of risk to the buyer have taken

and meeting the criteria for hedging future cash flows are recognised in the

place before year-end, and if the income can be reliably measured and is

Group's statement of comprehensive income under other comprehensive

expected to be received.

income. Income and expenses related to such hedging transactions are transferred from other comprehensive income on invoicing of the hedged

The value of services rendered is recognised on the basis of the delivered

item and included in the same item as the hedged item.

percentage of the total service.

Changes in the fair value of derivatives classified as hedging instruments

Revenue from subscriptions is allocated to the income statement on a

and meeting the criteria for hedging the fair value of a recognised asset or

straight-line basis.

liability are recognised in the income statement together with changes in the value of the hedged asset or liability.

Revenue from sales of goods is recognised when the significant risks and rewards of ownership have been transferred to the buyer.

For derivatives which do not qualify for hedge accounting, changes in fair value are recognised in the income statement under net financials as they

Revenue is measured at the fair value of the agreed consideration exclud-

arise.

ing VAT and other taxes collected on behalf of third parties. All discounts granted are recognised in revenue.

Changes in the fair value of derivatives used to hedge net investments in independent foreign subsidiaries or associates and which otherwise meet

Cost of sales

the relevant criteria are recognised in the Group's statement of comprehen-

Cost of sales comprises the cost of goods and services sold. Cost includes

sive income under other comprehensive income.

the cost of raw materials, transport costs, consumables and goods for resale, direct labour and indirect costs of production, including costs for operating

Securities, available-for-sale financial assets and derivatives measured at

and maintaining production facilities and equipment, amortisation/deprecia-

fair value are classified as belonging to levels 1-3 depending on the pricing

tion and impairment losses relating to such assets. Cost of sales moreover

method applied. Level 1 includes financial assets for which the fair value is

includes expenses in connection with quality assurance of products and any

measured on the basis of quoted prices (unadjusted) in active markets for

writedown to net realisable value of unsaleable and slow-moving items. Cost

identical assets. Level 2 includes financial assets and financial liabilities for

of sales also includes external assistance to generate the year's income.

which the fair value is measured on the basis of directly or indirectly observable inputs other than the quoted prices included in level 1. Level 3 includes

CONSOLIDATED FINANCIAL STATEMENTS

45


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

Research and development costs

The Lundbeck Foundation has opted to use section 3(4) of the Danish Cor-

Research and development costs comprise expenses incurred during the

poration Tax Act. Under these rules, the taxable income of Lundbeckfond

year in connection with the Group's research and development functions,

Invest A/S is considered to have been earned by the Lundbeck Foundation if

including wages and salaries, amortisation/depreciation and impairment and

the taxable income is distributed as dividends to the Lundbeck Foundation.

other indirect costs as well as costs relating to research and development

Since the Lundbeck Foundation's taxable income is regularly offset against

collaborations on in-licensed products.

grants for the year and provisions for future grants, no current or deferred tax is recognised.

Research costs are always recognised in the income statement as they are Tax for the year, which consists of the year's current tax and the change in

incurred.

deferred tax, is recognised in the income statement as regards the amount Development costs are capitalised if a number of specific criteria for capita-

that can be attributed to the net profit or loss for the year and directly in the

lising these costs are deemed to have been met. Otherwise, development

statement of comprehensive income under other comprehensive income as

costs will be recognised in the income statement as they are incurred.

regards the amount that can be attributed to items under other comprehensive income or directly in equity. Exchange rate adjustments of deferred

See Accounting policies and estimates critical to financial reporting for a

tax are recognised as part of the movements in deferred tax in the balance

description of conditions for capitalising development costs.

sheet.

Distribution costs

The current tax charge for the year is calculated based on the tax rates and

Distribution costs comprise expenses incurred in connection with the distri-

rules applicable at the balance sheet date.

bution of the Group's products sold during the year and in connection with sales campaigns, etc. launched during the year under review, including direct

Special items

distribution and marketing costs, salaries etc. for the sales and marketing

Special items comprise major one-off amounts not directly attributable to

functions, as well as amortisation/ depreciation and impairment and other

the Group's ordinary activities, and they concern matters such as amortisa-

indirect costs.

tion on contractual customer relationships identified at acquisitions and transaction costs associated with acquisitions.

Administrative expenses Administrative expenses comprise expenses incurred during the year for the management and administration of the Group, including expenses in con-

Balance sheet

nection with the administrative functions, management, office premises and office expenses, as well as amortisation/depreciation and impairment and

Intangible assets

other indirect costs.

Goodwill On initial recognition, goodwill is measured and recognised as the excess

Results of investments in associates

of the cost or fair value of the acquired business over the fair value of the

The proportionate share of the results of associates is recognised in the

acquired assets, liabilities and contingent liabilities. On recognition of good-

consolidated income statement after tax and elimination of the proportion-

will, the goodwill amount is allocated to those of the Group’s activities that

ate share of any intra-group gains and losses and after deduction of any

generate separate cash flows (cash-generating units).

writedowns of the equity investments. Goodwill is not amortised, but is tested for impairment at least once a year (impairment test), or if there is evidence of impairment.

Net financials Net financials include interest income and expenses, including the interest component of financial lease payments, which are recognised in the income

Development projects

statement at the amounts relating to the financial year. Net financials also

Clearly defined and identifiable development projects are recognised as

include value adjustments of financial assets and realised and unrealised

intangible assets where the technical rate of utilisation of the project, the

gains and losses on investments, unhedged items denominated in foreign

availability of adequate resources and a potential future market or develop-

currencies as well as forward contracts and other derivatives not used for

ment opportunity in the company can be demonstrated and where the

hedge accounting, realised exchange gains and losses concerning addi-

intention is to manufacture, market or use the project if the cost can be

tions to net investments in foreign subsidiaries that are recycled from other

measured reliably and it is probable that the future earnings can cover

comprehensive income. Dividends to capital holders who have received put

production and selling expenses, administrative expenses as well as the

options in connection with business combinations are recognised as a finan-

development costs. Other development costs are recognised in the income

cial expense in the cases where the option price is independent of dividend

statement as the costs are incurred.

payments and other financial expenses. After completion of the development work, development costs are amorTax

tised on a straight-line basis over the expected useful life. For development

The Group's controlled Danish companies are jointly taxed with Lundbeck-

projects protected by intellectual property rights, the maximum amortisation

fond Invest A/S as administration company. The current Danish income tax

period is the remaining term of the rights concerned. Ongoing development

liability is allocated among the companies of the tax pool in proportion to

projects are tested for impairment at least once a year, or if there is evidence

their taxable income (full allocation subject to reimbursement in respect of

of impairment.

tax losses).

46

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

Other intangible assets

Acquired intellectual property rights in the form of product rights, contrac-

Buildings

years

tual customer relationships, patents, licenses, brand names and software are

Installations 10

measured at cost less accumulated amortisation and impairment. The cost of

Plant and machinery

software comprises the cost of planning, including labour and costs directly

Vehicles by category

5-12

attributable to the project.

Other fixtures and fittings, tools and equipment

3-10

25-50 3-10

Leasehold improvements max.

10

Product rights are amortised on a straight-line basis over the economic lives of the underlying products. Contractual customer relationships are measured

The depreciation base is cost less the estimated residual value at the end

at cost less accumulated depreciation and impairment. Intangible assets

of the expected useful life. The cost of a total asset is divided into smaller

acquired on acquisition are amortised over the expected economic life,

components that are depreciated separately if such components have diffe-

estimated to be 3 to 10 years. Patents are amortised over a maximum of the

rent useful lives. Depreciation methods, useful lives and residual values are

remaining life of the patent. Licenses are amortised over the period of the

re-assessed annually.

agreement. Software is amortised over the expected economic life, estimated to be 3 to 5 years. The economic lives of large administrative systems are

Depreciation is recognised in the income statement under cost of sales,

estimated to be 8 years. Amortisation commences when the asset is ready

distribution costs, administrative expenses and research and development

to be brought into use, which means at the time of commercialisation.

costs, respectively.

Depreciation is recognised in the income statement under cost of sales,

The costs of maintaining property, plant and equipment are recognised in

distribution costs, administrative expenses and research and development

the income statement as they are incurred, either directly in the income

costs, respectively.

statement or as part of indirect costs of production.

Other intangible assets with indeterminable useful lives are not amortised

Costs incurred that increase the recoverable amount of the asset concerned

but tested for impairment at least once a year, or if there is evidence of

are added to the asset's cost as an improvement and are depreciated over

impairment.

the expected useful life of the improvement.

Borrowing costs to finance the manufacture of other intangible assets are

Gains or losses on the sale or retirement of items of property, plant and

recognised in the cost price if such borrowing costs relate to the production

equipment are calculated as the difference between the carrying amount

period. Other borrowing costs are expensed.

and the selling price reduced by costs relating to divestment or discontinuance. Gains and losses are recognised in the income statement under the

Gains and losses on the disposal of development projects, patents and

same item as the associated depreciation.

licenses are measured as the difference between the selling price less cost to sell and the carrying amount at the time of sale.

Impairment Goodwill is written down through the income statement in those cases

See Accounting policies and estimates critical to financial reporting for a

where the carrying amount exceeds the future net income expected from

description of the calculation of the fair value of intangible assets.

the cash-generating unit (CGU) to which the goodwill relates (recoverable amount). In the impairment test, the discounted expected future cash flows

Property, plant and equipment

(value in use) for each CGU are compared to the carrying amounts of good-

Property, plant and equipment are measured at cost less accumulated

will and other net assets.

depreciation and impairment. Land is not depreciated. The carrying amount of intangible assets and property, plant and equipment Cost includes the costs of purchase and expenses directly attributable to

is analysed in connection with the preparation of the consolidated financial

the purchase until the asset is ready for use. In the case of assets manufac-

statements if there are indications that the carrying amount of an asset

tured by the company, cost includes expenses directly attributable to the

may exceed the expectations of future income from the asset (recoverable

manufacture of the asset, including materials, components, subsupplies and

amount). If this analysis concludes that the future expected net income from

labour.

the asset will be lower than the carrying amount, the carrying amount will be reduced to the higher of fair value less cost to sell and value in use. Impair-

Assets held under finance leases are recognised under property, plant and

ment losses are recognised in the income statement under the same items

equipment and measured at the lower of the fair value and value in use of

as the associated depreciation or amortisation.

the future lease payments at the inception of the lease. Assets held under finance leases are depreciated over the useful lives of the assets or, if shorter,

Investments in associates

over the lease term.

Investments in associates are recognised and measured in the consolidated financial statements according to the equity method, which entails that the

Borrowing costs to finance the manufacture of property, plant and equip-

investments are measured in the balance sheet at the proportionate share

ment are recognised in the cost price if such borrowing costs relate to the

of the associate's net asset value calculated in accordance with the Group'

production period. Other borrowing costs are expensed.

accounting policies less or plus unrealised intra-group gains and losses and plus the carrying amount of goodwill.

Property, plant and equipment are depreciated on a straight-line basis over the expected useful lives of the assets, which are expected to be as follows:

CONSOLIDATED FINANCIAL STATEMENTS

47


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

The proportionate share of the result of the associate is recognised in the

Inventories

income statement after tax and elimination of the proportionate share of any

Raw materials, packaging and goods for resale are measured at the latest

intra-group gains and losses and after deduction of any writedowns of the

known cost at the balance sheet date, which equals cost computed accord-

investments. The proportionate share of all transactions and events recog-

ing to the FIFO method. Work in progress and finished goods manufac-

nised directly in the associate's other comprehensive income is recognised in

tured by the company are measured at cost, i.e. the cost of raw materials,

the Group's statement of comprehensive income under other comprehensive

consumables, direct labour and indirect costs of production. Indirect costs

income.

of production include materials and labour as well as maintenance of and depreciation on the machines, factory buildings and equipment used in the

Investments in associates with a negative carrying amount are recognised

manufacturing process as well as the cost of factory administration and

at DKK 0. Receivables and other long-term financial assets considered to

management. Indirect costs of production are allocated based on the normal

form part of the overall investment in the associate are written down by any

capacity of the production plant.

remaining negative net asset value. Trade receivables and other receivables are written down only to the extent they are deemed to be irrecoverable. A

Inventories are written down to net realisable value if it is lower than the

provision to cover the remaining negative net asset value will only be made

cost price. The net realisable value of inventories is determined as the selling

if the Group has a legal or constructive obligation to cover the liabilities of

price less costs of completion and costs necessary to make the sale and is

the relevant associate.

determined taking into account marketability, obsolescence and developments in the expected selling price.

Financial assets Securities that are included in the Group's documented investment strategy

Receivables

in accordance with the fair value option of IAS 39 Financial Instruments:

Current receivables comprise trade receivables and other receivables arising

Recognition and Measurement are recognised on the basis of the value date

in the Group's normal course of business. Other receivables recognised un-

at fair value and are subsequently measured at market price or estimated fair

der financial assets are financial assets with fixed or determinable payments

value at the balance sheet date. Bonds with a term to maturity of less than

that are not quoted in an active market and are not derivative financial

one year are recognised in current assets. Both realised and unrealised gains

instruments.

and losses are recognised in the income statement under net financials. On initial recognition, receivables are measured at fair value, which usually Financial assets are measured at fair value through profit or loss, including

corresponds to the nominal value less writedowns to counter the risk of loss

investments in associates if they are included in the Group's documented

calculated on the basis of an individual evaluation. A provision account is

investment strategy.

used for this purpose.

Bonds forming part of repo transactions, i.e. the selling of bonds to be

Prepayments

repurchased at a later date, remain in the balance sheet as financial assets,

Prepayments consist of expenses relating to subsequent financial years.

and the amount received on repo transactions is recognised as repo debt.

Prepayments are measured at cost.

Returns on such bonds are recognised in the normal manner under financials.

Securities The bond portfolio and other securities, which are included in the Group's

The fair value of listed investments is calculated using official currently

documented investment strategy for excess liquidity, or bonds with a term

quoted prices. The calculation of fair value of unlisted investments, including

to maturity of less than one year, are recognised under current assets, are

life science investments, is made in accordance with International Private

measured at the value date and measured at the market price a the balance

Equity and Venture Capital Valuation Guidelines. i.e. on the basis of relevant

sheet date. Both realised and unrealised gains and losses are recognised in

valuation methods based on comparable transactions on market conditions,

the income statement under net financials.

capital increases and the like. If the fair value cannot be determined with sufficient reliability, the investments in question are recognised at cost less any impairment. The Group assesses at each balance sheet date whether there is

Equity

objective evidence that an investment or a group of investments is impaired. Assessments of investments in unlisted equity instruments and securities,

Authorised grants

including life science investments, include an assessment of whether the

Grants are considered equity movements and are recognised as a liability at

companies live up to the defined business plans and the impact of any non-

the time when the grant has been authorised by the Board of Directors and

compliance on the calculation of fair value.

announced to the recipient. Authorised grants not yet disbursed are recognised in long-term or short-term liabilities, respectively.

On initial recognition, other investments classified as available-for-sale are measured at fair value with the addition of costs directly attributable to the

Hedging reserve

acquisition. Other investments are subsequently measured at fair value at

Hedge transactions that meet the criteria for hedging future cash flows and

the balance sheet date, and changes to the fair value are recognised in the

for which the hedged transaction has yet to be realised are recognised in

statement of comprehensive income under other comprehensive income

equity under the hedging reserve. Value adjustments concerning hedging

with the exception of impairment losses and dividends, which are taken to

transactions used to hedge the Group's net investment in such entities are

the income statement. When other investments available-for-sale are sold

recognised in equity under the hedging reserve.

or settled, the accumulated fair value adjustments recognised under other comprehensive income are recycled to net financials.

48

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

Currency translation reserve

The present value of the liability according to defined benefit plans is mea-

Foreign exchange adjustments arising on the translation of financial state-

sured less the fair value of the plan assets, and any net obligation is recog-

ments for entities which have a functional currency other than Danish kroner,

nised in the balance sheet under non-current liabilities. Any net asset is

foreign exchange adjustments relating to financial assets and liabilities

recognised in the balance sheet as a financial asset.

representing a part of the Group’s net investment in such entities are recognised in equity under the currency translation reserve. On full or partial

The year's changes in the provisions relating to defined benefit plans are

realisation of a net investment, foreign exchange adjustments are recognised

recognised in the income statement.

in the income statement. Income tax and deferred tax Reserve for fair value adjustment of available-for-sale financial assets

Current tax liabilities and receivables are recognised in the balance sheet,

Reserve for fair value adjustment comprises accumulated changes in the fair

computed as tax calculated on the taxable income for the year, adjusted for

values of available-for-sale financial assets. The reserve, which forms part of

provisional tax paid.

the Group’s free reserves, is dissolved and transferred to the income stateTax on items in other comprehensive income is recognised in the statement

ment as the investment is sold or written down.

of comprehensive income under other comprehensive income. Tax on equity entries is recognised in equity.

Treasury shares Cost and selling prices of treasury shares as well as dividends are recognised

Deferred tax is recognised on all temporary differences between the carry-

directly in equity under retained earnings.

ing amounts of assets and liabilities and their tax base, except for temporary Minority interests

differences arising either on initial recognition of goodwill or a transaction

The proportionate shares of the profits and equity of subsidiaries attribut-

that is not a business combination and with the temporary difference ascer-

able to minority interests are recognised as a separate item under equity. On

tained at the time of the initial recognition affecting neither the financial

initial recognition, minority interests are recognised as described under Busi-

result nor the taxable income. The tax value of the assets is calculated based

ness combinations. The issuance of put options as part of the consideration

on the planned use of each asset.

in business combinations is recognised as described under Acquisition and Deferred income tax is provided on temporary differences arising on invest-

divestment of minority interests.

ments in subsidiaries and associates, unless the Group has a possibility of Share-based payments

controlling when the deferred tax is to be realised and it is likely that the

Share-based incentive programmes in which employees may opt to buy

deferred tax will not materialise as current tax.

shares in H. Lundbeck A/S, ALK-Abelló A/S and Falck Holding A/S, and in which shares are allocated to employees (equity schemes) are measured at

Deferred tax is measured on the basis of the tax rates and tax rules in force

the equity instruments' fair value at the date of grant and recognised in the

in the respective countries on the balance sheet date. Changes in deferred

income statement under staff costs when or as the employee obtains the

tax as a result of changed tax rates or tax rules are recognised in the income

right to buy/receive the shares. The balancing item is recognised directly in

statement.

equity under other transactions. Deferred tax assets, including the tax value of tax loss carry-forwards, are Share price-based incentive programmes in which employees have the

recognised in the balance sheet at the value at which the asset is expected

difference between the agreed price and the actual share price settled in

to be realised, either through a set-off against deferred tax liabilities or as

cash (debt schemes) are measured at fair value at the date of grant and

net assets to be offset against future positive taxable income.

recognised in the income statement under staff costs when or as the employee obtains the right to such difference settlement. The incentive

Changes in deferred tax concerning the cost of share-based payments are

programmes are subsequently remeasured on each balance sheet date and

generally recognised in the income statement.

upon final settlement, and any changes in the fair value of the programmes are recognised in the income statement under staff costs. The balancing

Deferred tax in respect of recaptured losses previously deducted in foreign

item is recognised under provisions.

subsidiaries is recognised on the basis of a specific assessment of the intention with each individual subsidiary.

Pension obligations Periodical payments to defined contribution plans are recognised in the

Balances calculated according to the rules on interest deductibility limita-

income statement at the due date and any contributions payable are recog-

tions in the Danish Corporate Income Tax Act are allocated between the

nised in the balance sheet under current liabilities.

jointly-taxed companies according to a joint taxation agreement and are allocated between the companies that are subjected to deductibility limita-

The present value of the Group's liabilities relating to future pension pay-

tion in proportion to their share of the total limitation. Deferred tax liabilities

ments according to defined benefit plans is measured on an actuarial basis

in respect of these balances are recognised in the balance sheet, whereas

once a year on the basis of the pensionable period of employment up to the

deferred tax assets are recognised only if the criteria for recognition of

time of the actuarial valuation. The Projected Unit Credit Method is applied

deferred tax assets are met.

to determine the present value. The present value is calculated based on assumptions of the future developments of salary, interest, inflation, mortality

Other provisions

and disability rates and other factors. Actuarial gains and losses are recog-

Other provisions consist of different types of provisions, including provisions

nised in the income statement as they are calculated.

for pending lawsuits. Management makes assessments of provisions and

CONSOLIDATED FINANCIAL STATEMENTS

49


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

contingent liabilities, including the probable outcome of pending and pos-

for sale. A disposal group is a group of assets to be disposed of, by sale or

sible future lawsuits, which inherently depends on uncertain future events.

otherwise, together as a group in a single transaction. Liabilities regarding

When management determines the probable outcome of lawsuits and

assets held for sale are liabilities directly associated with those assets that

similar factors, it relies on assessments made by external advisers who are

will be transferred in the transaction. Assets are classified as held for sale if

familiar with the specific cases and the existing legal practice.

their carrying amount will be recovered principally through a sale transaction within 12 months in accordance with a formal plan rather than through

Provisions for restructuring are recognised when a detailed, formal plan for

continuing use.

the restructuring has been made before or on the balance sheet date and has been announced to the parties involved. In connection with acquisi-

Assets or disposal groups held for sale are measured at the lower of the car-

tions, provisions for restructuring costs are only included in the computation

rying amount at the date when the assets were classified as held for sale and

of goodwill if an obligation exists for the entity acquired as of the date of

fair value less costs to sell. Assets are not depreciated or amortised as from

acquisition.

the date they are classified as “held for sale�.

Provisions are made for onerous contracts when the anticipated benefits to

Impairment losses from the initial classification of the non-current assets

the Group from a contract are outweighed by the unavoidable costs under

as held for sale as well as gains and losses from following measurement of

the contract.

the lowest value of the carrying amount or the fair value less sales costs are recognised in the income statement in the items to which they relate. Gains

When the Group is under an obligation to dismantle an asset or re-establish

and losses are disclosed in the notes to the financial statements.

the site where the asset has been used, a provision is made corresponding to the present value of the expected future costs. The provision is determined

Assets and related liabilities are recognised separately in the balance sheet,

based on current orders and estimated future costs, discounted to their

and the main items are specified in the notes to the financial statements.

present value. The discount factor used reflects the general level of interest

Comparative figures in the balance sheet are not restated.

rates. The present value of the costs is recognised in the cost of the item of property, plant and equipment in question and depreciated with these as-

Leases

sets. The increase of the present value over time is recognised in the income

For accounting purposes, lease obligations are divided into finance and

statement under financial expenses.

operating leases. Leases are classified as finance leases when substantially all risks and rewards of ownership of the leased asset are transferred. Other

Other provisions are recognised when the Group has a legal or constructive

leases are classified as operating leases.

obligation that arises from past events and it is probable that an outflow of The accounting treatment of assets held under finance lease and the related

financial resources will be required to settle the obligation.

liability is described in the sections on property, plant and equipment and Other provisions are measured as the best estimate of the costs required to

financial liabilities, respectively.

settle the liabilities at the balance sheet date. Assets held under operating leases are not recognised in the balance sheet. Return obligations imposed on the industry are recognised in the balance

Lease liabilities under operating leases are disclosed as contingent liabilities.

sheet under other provisions.

Lease payments concerning operating leases are recognised in the income statement on a straight-line basis over the term of the lease.

Debt Mortgage debt and debt to credit institutions are recognised at the time of

Cash flow statement

the raising of the loan at proceeds received less transaction costs paid. In

The consolidated cash flow statement is presented according to the indirect

subsequent periods, the financial liabilities are measured at amortised cost,

method and shows the composition of cash flows, divided into operating,

equivalent to the capitalised value when the effective rate of interest is used,

investing and financing activities respectively, and the cash and cash equiva-

so that the difference between the proceeds and the nominal value is recog-

lents at the beginning and at the end of the year.

nised in the income statement over the loan period. Cash flows from acquisitions and divestments of companies are shown sepaResidual lease commitments from finance leases are recognised at amor-

rately under cash flows from investing activities. The cash flow statement

tised cost.

includes cash flows from acquired companies from the date of acquisition and cash flows from divested companies until the time of divestment.

Repo debt relates to bonds included in repo transactions. Debt is recognised at amortised cost, and accumulated repo interest has been accrued.

Cash flows from operating activities are calculated as the Group's profit from operations and special items, adjusted for non-cash operating items, working

Debt included in the short-term financial liquidity is also measured at amor-

capital changes, financial receipts and payments and income taxes paid.

tised cost in subsequent periods. Cash flows from investing activities include payments in connection with Other payables, which include trade payables and debt to public authorities

purchases and sales of intangible assets, property, plant and equipment and

etc. are measured at amortised cost.

financial assets, including equity investments in companies. Also included are securities classified as current assets. Entering into a finance lease is considered a non-cash transaction.

Assets held for sale Assets held for sale comprise non-current assets and disposal groups held

50

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1

Cash flows from financing activities include payments to and from shareholders and related expenses as well as the raising of and repayments on loans, mortgage debt and other long-term debt and cash flows from dividends and minorities. Cash comprises cash less current bank debt falling due on demand. Cash flows denominated in foreign currencies, including cash flows in foreign subsidiaries, are translated at the average exchange rates during the year because they approximate the actual exchange rates at the date of payment. Cash at year-end is translated at the exchange rates at the balance sheet date, and the effect of exchange rate adjustments on cash is shown as a separate item in the cash flow statement. Key figures Financial key figures are calculated according to Recommendations and Financial Ratios 2010 issued by the Danish Society of Financial Analysts. EBIT: defined as the Group's profit before special items, financial items and tax. EBIT margin:

EBIT operations x 100 / Revenue

Return on equity: Lundbeck Foundation's share of profit x 100

/ Lundbeck Foundation's share of average equity

CONSOLIDATED FINANCIAL STATEMENTS

51


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 2 - 3

2. REVENUE 2011 2010 DKKm DKKm Europe

14,468

9,992

USA

4,708

3,722

Rest of the world

4,426

3,213

23,602

16,927

CNS pharmaceuticals (H. Lundbeck Group)

16,007

14,765

Allergy pharmaceuticals (ALK Group)

2,348

2,162

Emergency, assistance, healthcare and training (Falck Group)

5,247

-

23,602

16,927

Revenue includes:

Downpayments and milestone payments

448

37

Royalty

640

620

Revenue in Denmark

2,878

143

Income from Forest in the USA Income from sales of citalopram and escitalopram to Forest amounted to DKK 2,535 million in 2011 (DKK 2,443 million in 2010) based on the minimum price for this year’s shipments and adjustments of prepayments concerning prior-year shipments. Prepayments, which is the difference between the invoiced price and the minimum price, were DKK 234 million at 31 December 2011 (DKK 517 million in 2010). See Note 1 Accounting policies for a more elaborate description hereof.

The agreement with Forest takes into consideration the expiry of the escitalopram patent protection in the USA in 2012. Prior to any launch of generic citalopram, Forest is expected to reduce its escitalopram inventories to a low level.

Developments in Forest’s inventories and net selling price are monitored closely, and the risk of the price adjustment clause and repayment of the prepayment being applied is regularly assessed. It is believed that there is presently no repayment risk.

Other accrued income There is deferred income concerning research and development partnerships amounted to DKK 74 million. Furthermore there is accrued subscription revenue in the amount of DKK 1,036 million and other accrued income of DKK 295 million regarding the Falck Group.

3. STAFF COSTS 2011 2010 DKKm DKKm Short-term staff benefits

6,607

Share-based payment

34

3,743 21

Pension benefits

414

283

Other social security costs

707

465

7,762

4,512

The year's staff costs are specified as follows: Cost of sales

3,072

684

Research and development costs

1,309

1,155

Distribution costs

1,755

1,492

Administrative expenses

1,626

1,181

Total 7,762 4,512 Total remuneration in the Group for the Executive Management of the Foundation amounts to

4

2

Total remuneration in the Group for the Board of Directors of the Foundation amounts to

7

6

Remuneration of the Executive Management and the Board of Directors is specified as follows: Executive Management:

Christian Dyvig, appointed on 1 June 2011

2.6

52

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 3 3. STAFF COSTS, CONTINUED

2011 DKKm

Board of Directors: Mikael Rørth, Chairman of the Foundation and Lundbeckfond Invest A/S, chairman of the research committee,

the biomedical sciences committee and the investment committee

0.8

Jørgen Huno Rasmussen, Deputy Chairman of the Foundation, member of the investment committee

0.4

Kim Klitgaard, employee representative

0.2

Ken Liljegren, employee representative

0.2

Thorleif Krarup, deputy chairman of Lundbeckfond Invest A/S, member of the investment committee,

deputy chairman of H. Lundbeck A/S, chairman of ALK-Abelló A/S and deputy chairman of Falck Holding A/S

2.6

Povl Krogsgaard-Larsen, member of the investment, research and the biomedical and natural sciences committees

0.2

Gunhild Waldemar, member of the research committee and the biomedical sciences committee

0.2

Peter Adler Würtzen, employee representative

0.2

Jes Østergaard, chairman of the natural sciences committee and member of the research and investment committees and board member of H. Lundbeck A/S and of ALK-Abelló A/S

1.7

Nils Axelsen, stepped down on 30 May 2011

0.2

Mogens Bundgaard-Nielsen, stepped down on 30 May 2011

0.4

7.1 2011 2010 Average number of full-time employees during the year

15,875

7,314

Number of employees at year-end (FTE)

24,676

7,352

Incentive programmes The Executive Management of the Foundation is not offered incentive programmes. An incentive programme has been launched for employees of Lundbeckfond Ventures which is similar to standard incentive programmes for the venture industry. The purpose of the incentive programme is for Lundbeckfond Ventures to be able to attract and retain skilled and qualified employees.

In order to attract, retain and motivate key employees and align their interests with those of the shareholders, the Group has established a number of incentive programmes in the H. Lundbeck, ALK and Falck groups. The Group has used equity-based as well as debt-based schemes, and the tables below show all the incentive programmes in place in 2010 and 2011.

Equity-based schemes Equity-based schemes are used both in H. Lundbeck A/S, ALK-Abelló A/S and Falck Holding A/S.

For the schemes in H. Lundbeck A/S, each warrant entitles the holder to buy one share of DKK 5 nominal value in the company. Furthermore the Executive Management has been granted share schemes. Exercise of the warrants and the share schemes is subject to the relevant employees continuing employment at the date of exercise. For warrants and share schemes to the Executive Management, exercise is also subject to H. Lundbeck A/S' shareholder return relative to a peer group. For the schemes in ALK-Abelló A/S, each warrant entitles the holder to buy one B share of DKK 10 nominal value in the company. The right to exercise the warrants is subject to the holder of the option not having resigned at the time of exercise. There are no other conditions for vesting. The options can be exercised only during a period of four weeks after the publication of annual or interim financial statements. Share options are considered adequately secured in own shares. For the scheme in Falck Holding A/S, each warrant entitles the holder to buy one share of DKK 1 nominal value in the company. The warrants issued were acquired at market value, and no conditions were attached. Consideration for the issued warrants has been paid in the form of a non-cash contribution of a corresponding number of warrants in Falck A/S, which have subsequently been cancelled.

Debt-based schemes H. Lundbeck A/S has granted Stock Appreciation Rights (SARs) and Restricted Cash Units (RCUs) to a few employees of US subsidiaries. SAR is a share price-based scheme with conditions and award criteria similar to those of the warrant schemes. RCU is a share price-based scheme with conditions and award criteria similar to those of the share schemes. Neither of the two schemes can be converted into shares, but the value of the scheme is distributed as a cash amount. The following tables show all the incentive programmes in place in 2010 and 2011.

CONSOLIDATED FINANCIAL STATEMENTS

53


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 3 3. STAFF COSTS, CONTINUED

Conditions for the various incentive programmes are set out below: Exercise Exercise Number of Outstanding at H. Lundbeck A/S - equity-based schemes

Vesting

period

date

begins

period

warrants/

Exercise

31 December

ends shares granted

price

2011

2007, warrants

Immediately

1/8 2008

31/3 2011

844,500

156.00

-

2008, warrants

6/5-2/6 2011

6/5-2/6 2011

5/5-1/6 2016

539,544

115.00

151,870 477,919

2009, warrants

16/3 2012

16/3 2012

15/3 2017

534,058

102.00

2010, warrants

16/3 2013

16/3 2013

15/3 2018

790,950

97.00

711,809

2011, warrants

31/3 2014

1/4 2014

31/3 2019

849,085

121.00

786,103

2008, share scheme

6/5-2/6 2011

74,609

434

2009, share scheme

16/3 2012

92,627

85,449

16/3 2013

102,689

96,785

31/3-30/6 2014

539,962

511,284

2010, share scheme 2011, share scheme

H. Lundbeck A/S

- debt-based schemes 2008, SARs

11/8 2011

11/8 2011

11/8 2016

2,258

2008, RCUs

11/8 2011

814

-

2009, SARs

1/7 2012

1/7 2012

30/6 2017

241,137

102.00

2,352

2009, RCUs 2010, SARs

119.76

2,258

1/7 2012

338,975

845

16/3 2013

16/3 2013

15/3 2018

36,060

97.00

4,639

2010, RCUs

16/3 2013

10,346

1,331

2011, SARs

31/3 2014

16/3 2014

15/3 2019

53,832

121.00

53,832

2011, RCUs

31/3-30/6 2014

66,233

66,233

ALK-Abell贸 A/S

- equity-based schemes 2005/06, share options

1/1 2009

1/1 2009

1/1 2012

68,000

742.00

2006, share options

1/11 2009

1/11 2009

1/11 2013

33,375

896.00

53,000 28,725

2007, share options

1/11 2010

1/11 2010

1/11 2014

29,000

727.00

26,050 41,950

2008, share options

1/11 2011

1/11 2011

1/11 2015

47,600

504.00

2009, share options

1/11 2012

1/11 2012

1/11 2016

58,300

465.00

51,525

2010, share options

1/11 2013

1/11 2013

1/11 2017

174,000

345.00

167,100

2011, share options

1/11 2014

1/11 2014

1/11 2018

220,000

319.00

220,000

The exercise price for ALK-Abell贸 A/S' schemes equals the average of the market price during the last five business days prior to the date of grant. The exercise price is increased by 2.5% p.a. and reduced by dividends paid. For the 2005/06 scheme, the exercise price equals the average of the market price during the last ten business days prior to the date of grant. The exercise price is increased by 6% p.a. and reduced by dividends paid.

Exercise Falck Holding A/S - equity-based schemes

Acquisition

period

date

begins

13/7 2011

30/12 2015

Exercise period

Number of Outstanding at warrants/

Exercise

31 December

ends shares granted

price

2011

125.00

4,443,120

2011, warrants

30/12 2015

4,443,120

54

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 3 3. STAFF COSTS, CONTINUED

Outstanding warrants

Outstanding

and share schemes 2011

at 1 January

Additions

Exercised/

Expired/ Outstanding at

settled

cancelled

31 December 2,127,701

H. Lundbeck A/S, warrants

2,693,412

849,085

(19,284)

(1,395,512)

H. Lundbeck A/S, share scheme

264,437

539,962

(69,505)

(40,942)

693,952

ALK-Abelló A/S, share options

382,150

220,000

(13,800)

588,350

Falck Holding A/S, warrants

-

4,443,120

-

4,443,120

Total 2011

3,339,999

6,052,167

- - (88,789)

(1,450,254)

7,853,123

Outstanding warrants and share schemes 2010 H. Lundbeck A/S, warrants

1,902,462

790,950

-

-

2,693,412

H. Lundbeck A/S, share scheme

161,748

102,689

-

-

264,437

ALK-Abelló A/S, share options

225,975

174,000

-

(17,825)

382,150

Total 2010

2,290,185

1,067,639

-

(17,825)

3,339,999

Outstanding debt-based schemes 2011 H. Lundbeck A/S, SARs

132,106

53,832

-

(122,857)

63,081

H. Lundbeck A/S, RCUs

251,917

66,233

(814)

(248,927)

68,409

Total 2011

384,023

120,065

(814)

(371,784)

131,490

132,106

2010 H. Lundbeck A/S, SARs

171,036

36,060

-

(74,990)

H. Lundbeck A/S, RCUs

297,552

10,346

-

(55,981)

251,917

Total 2010

468,588

46,406

-

(130,971)

384,023

Recognised expenses The warrants and shares granted are recognised in the income statement for 2011 at an expense corresponding to the fair value at the time of grant calculated according to the Black-Scholes method for the vesting period to date. For the warrants and shares in the 2008, 2009, 2010 and 2011 programmes that depend on the Lundbeck share’s ranking in the peer group of companies, the recognised expense was calculated with due consideration to fulfilment of the vesting conditions. The SARs granted are recognised in the income statement for 2011 at an expense corresponding to the value adjustment for the year based on the BlackScholes method, and the RCUs granted are recognised in the income statement for 2011 at an expense corresponding to the value adjustment for the year based on the performance of the Lundbeck share. 2011 2010 DKKm DKKm Recognised expenses concerning equity-based schemes

33

26

Recognised expenses concerning debt-based schemes

1

(5)

Total recognised expenses

34

21

CONSOLIDATED FINANCIAL STATEMENTS

55


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 3 - 4 3. STAFF COSTS, CONTINUED

The assumptions applied in determining the fair value of warrant, share option and debt-based schemes at the grant date are as follows:

Market price at

Expected divi- dend payout

Risk-free

Expected

Calculated

time of grant,

Expected

DKK

volatility, %

March 2009

98.75

44.05

1.50

3.20

79

40.37

H. Lundbeck A/S, debt-based scheme, June 2009

96.79

36.34

1.50

3.38

79

36.42

99.55

32.29

1.50

2.60

66

29.86

95.70

31.70

1.50

1.73

60

24.30

ratio, % interest rate, % maturity, mths.

fair value per option, DKK

H. Lundbeck A/S, warrant and share scheme,

H. Lundbeck A/S, warrant, share and debt-based scheme, March 2010 H. Lundbeck A/S, warrant and share scheme, October 2010 H. Lundbeck A/S, warrant, share and debt-based scheme, April 2011

121.20

31.03

2.50

2.99

66

30.10

ALK-Abell贸 A/S, 2009 scheme

465.00

45.00

0.97

3.58

60

173.00

ALK-Abell贸 A/S, 2010 scheme

345.00

25.00

1.31

2.21

60

63.00

ALK-Abell贸 A/S, 2011 scheme

319.00

24.00

1.42

1.68

60

52.00

Warrants for subscription of shares in Falck Holding A/S were acquired at fair value. 4. DEPRECIATION, AMORTISATION AND IMPAIRMENT

Intangible Property, plant

assets and equipment

DKKm

DKKm

Total DKKm

Depreciation, amortisation and impairment for 2011 are specified as follows Cost of sales

121

232

Research and development costs

216

399

353 615

Distribution costs

406

25

431

Administrative expenses

31

99

130

Special items

242

-

242

1,016

755

1,771

An impairment loss on other rights totalling DKK 47 million is included in cost of sales in the amount of DKK 31 million, in research and development costs in the amount of DKK 11 million and in administrative expenses in the amount of DKK 5 million.

An impairment loss on patent rights totalling DKK 95 million is included in research and development costs. An impairment loss on property, plant and equipment totalling DKK 283 million mainly consists of impairment of land and buildings in the USA. The impairment loss is included in cost of sales in the amount of DKK 21 million, in research and development costs in the amount of DKK 258 million and in administrative expenses in the amount of DKK 4 million.

Losses and gains on the sale of intangible assets and property, plant and equipment are recognised at a net gain of DKK 113 million. Of this amount, the gain from the sale of production facilities in the UK amounts to DKK 95 million.

Intangible Property, plant

assets and equipment

DKKm

DKKm

Total DKKm

Depreciation, amortisation and impairment for 2010 are specified as follows Cost of sales

101

192

Research and development costs

115

177

292

Distribution costs

427

13

440

Special items

27

80

670

462

The distribution costs for 2011 include a DKK 48 million impairment loss on product rights. Losses and gains on the sale of intangible assets and property, plant and equipment were recognised at a net loss of DKK 33 million.

56

CONSOLIDATED FINANCIAL STATEMENTS

293

107 1,132


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 5 - 6 - 7

5. FEES TO AUDITORS APPOINTED AT THE GENERAL MEETING

Deloitte

2011

2010

KPMG 2011

2010

DKKm DKKm DKKm DKKm Administrative expenses include fees to the company's auditors appointed by the general meeting in the amount of: Statutory audit

10

11

6

-

Assurance engagements other than audits

1

-

-

-

Tax advice

2

3

-

-

Other services

6

6

1

-

19

20

7

-

The Falck Group is audited by KPMG. A few small foreign subsidiaries are not audited by the Foundation's auditors, a foreign business partner of the auditors, or by an internationally recognised accountancy firm. 6. SPECIAL ITEMS

2011 2010 DKKm DKKm

242

-

Amortisation of contractual customer relationships, Falck Group associate

Amortisation of contractual customer relationships, Falck Group

69

-

311

51

-

Special items

Transaction costs in connection with acquisitions

362

-

7. NET FINANCIALS ITEMS

2011 2010 DKKm DKKm

Financial income Interest on financial assets measured at amortised cost

63

Gains on financial assets measured at fair value through profit or loss

21

-

Gains on available-for-sale financial assets, incl. dividends

14

5

521

1,171

Gains on financial instruments measured at fair value through profit or loss

Gains on loan to associate that has been written down

26

-

9

Gains on financial instruments included in the trading portfolio

66

127

Exchange gains

305

124

Exchange gains concerning additions to net investments in foreign subsidiaries (transferred from comprehensive income)

4

-

Total financial income

813

1,643

Financial expenses Interest on financial liabilities measured at amortised cost

253

Loan conversion expenses

15

115 -

Other financial expenses

27

19

Losses on available-for-sale financial assets

3

-

638

158

Losses on financial instruments included in the trading portfolio

131

191

Interest component, discounted liabilities

2

-

94

77

Losses on financial instruments measured at fair value through profit or loss

Exchange losses

Exchange losses concerning additions to net investments in foreign subsidiaries (transferred from comprehensive income)

24

-

Total financial expenses

1,187

560

Net financials

(374)

1,083

At 31 December 2011, the Group recorded a net gain on available-for-sale financial assets of DKK 11 million (net loss of DKK 5 million in 2010).

CONSOLIDATED FINANCIAL STATEMENTS

57


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 7 - 8 7. NET FINANCIALS ITEMS, CONTINUED

The net loss on financial instruments measured at fair value through profit or loss amounted to DKK 117 million at 31 December 2011 (net gain of DKK 1,013 million in 2010). The net loss on financial instruments included in the trading portfolio amounted to DKK 65 million (loss of DKK 64 million in 2010), and the net exchange gain, including realised net exchange loss transferred from other comprehensive income, amounted to DKK 10 million in 2011 (net gain of DKK 228 million in 2010).

8. TAX ON PROFIT FOR THE YEAR

2011 2010 DKKm DKKm Current tax

1,056

Prior-year adjustment, current tax

6

1,118 49

Prior-year adjustment, deferred tax

12

(24)

Change of deferred tax for the year

45

(193)

Total tax for the year

1,119

950

Tax for the year is composed of: Tax on profit for the year

1,100

Tax on other comprehensive income

19

899 51

Total tax for the year

1,119

950

Tax on other comprehensive income is specified as follows: Currency translation concerning additions to net investments in foreign subsidiaries

41

63

Realised exchange gains/losses, additions to net investments in foreign subsidiaries (transferred to profit and loss)

5

-

Adjustment, deferred exchange gains/losses, hedging

21

(53)

Exchange gains/losses, hedging (transferred to the hedged items)

(37)

41

Exchange gains/losses, hedging (transferred from hedging)

-

-

Value adjustment of interest hedging instruments

(11)

-

Tax on other comprehensive income

19

51

Explanation of the Group's effective tax rate relative to the Danish tax rate 2011

DKKm

%

Profit before tax

3,529

Calculated tax, 25%

882

25.0

Tax effect of: Differences in the tax rates of foreign subsidiaries from the Danish tax rate of 25%

(53)

Non-deductible expenses/non-taxable income and other permanent differences

123

3.5

Research and development activities (tax credits)

(77)

(2.2)

Prior-year tax adjustments etc., total effect on operations

24

0.7

8

0.2

Unrecognised timing differences on securities recognised at fair value through profit or loss

(2)

(0.1)

Change in valuation of net tax assets

228

Deduction for grants

Other taxes and other adjustments

15

0.4

Effective tax for the year

1,100

31.2

Non-deductible losses/non-taxable gains on shares and other equity investments

58

CONSOLIDATED FINANCIAL STATEMENTS

(48)

(1.5)

6.5 (1.4)


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 8 - 9 8. TAX ON PROFIT FOR THE YEAR, CONTINUED

Explanation of the Group's effective tax rate relative to the Danish tax rate 2010

DKKm

%

Profit before tax

4,596

Calculated tax, 25%

1,148

25.0

Tax effect of: Differences in the tax rates of foreign subsidiaries from the Danish tax rate of 25%

(25)

Non-deductible expenses/non-taxable income and other permanent differences

75

Research and development activities (tax credits)

(94)

(2.0)

Prior-year tax adjustments etc., total effect on operations

25

0.5

2

0.0

Unrecognised timing differences on securities recognised at fair value through profit or loss

(77)

(1.7)

Change in valuation of net tax assets

46

Deduction for grants

(198)

Other taxes and other adjustments

(3)

(0.1)

Effective tax for the year

899

19.6

Non-deductible losses/non-taxable gains on shares and other equity investments

(0.5) 1.6

1.0 (4.3)

9. GRANTS FOR THE YEAR

2011 2010 DKKm DKKm

Grants for the year can be specified as follows: Biomedical sciences projects

182

Natural sciences projects

26

192 28

Fellowships

70

50

Other

21

10

Regular grants

299

280 50

Grants of Excellence

-

Centres of Excellence

84

24

Grete Lundbeck European Brain Research Foundation

-

30

Psychiatric research (iPSYCH)

121

-

Strategic initiatives

205

104

Grants for the year, gross

504

384

Descendants Reversed grants/repayments

Grants for the year, net

-

-

(6)

(1)

498

383

CONSOLIDATED FINANCIAL STATEMENTS

59


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 10

10. INTANGIBLE ASSETS Contractual customer relationships Cost at 1 January 2011 Currency translation Reclassification Addition through acquisitions

Goodwill

Product

Patent

and license

Other Projects

intangible

in

etc. rights rights assets progress Total

DKKm DKKm DKKm DKKm DKKm DKKm DKKm 4,317

-

4,570

683

1,342

179

34

58

-

1

75

-

1

-

-

100

-

-

127

11,039

-

272

(75)

1

5,256

3,220

-

8,576

and contingent consideration

1

-

-

-

-

-

1

Additions

-

-

1,143

4

104

34

1,285

-

-

(264)

(3)

(22)

9,753

3,254

5,582

687

1,545

64

20,885

(19)

-

(979)

(360)

(963)

-

(2,321)

(1)

(7)

(31)

Adjustment of put options

Disposals Cost at 31 December 2011 Amortisation and impairment at 1 January 2011 Currency translation

-

-

-

-

(289)

(39)

Reclassification

-

-

-

-

(1)

-

(1)

Amortisation

-

(242)

(435)

(40)

(151)

-

(868)

Impairment

-

-

-

(95)

(47)

-

(142)

Amortisation and impairment on disposal

-

-

133

-

3

-

136

(20)

(249)

(1,312)

(495)

(1,159)

-

(3,235)

Carrying amount at 31 December 2011

9,733

3,005

4,270

192

386

64

17,650

Carrying amount at 31 December 2010

4,298

-

3,591

323

379

127

8,718

Amortisation and impairment at 31 December 2011

Goodwill impairment test The management of respectively H. Lundbeck A/S, ALK-Abelló A/S and Falck Holding A/S have tested intangible assets for impairment. Based on the impairment tests performed in 2011, it was concluded that there is no need for writing down the goodwill.

Methodology In the impairment test, the discounted expected future cash flows (value in use) pursuant to the most recent management-approved budgets for each CGU are compared to the carrying amounts of goodwill and other net assets. The future cash flows are based on specific business plans for the next 3-8 years with due consideration to patent expiry.

The key parameters in the calculation of the value in use are revenue, earnings, working capital, discount factor and the preconditions for the terminal period. Negative growth is projected in the H. Lundbeck Group in the terminal period due to patent expiry, and growth of 2-3% and 2% is projected for the Falck Group and the ALK Group, respectively.

The calculation of the value in use for the H. Lundbeck Group, excl. Lundbeck Inc., is based on a discount rate of 9.7% (9.5% in 2010). For Lundbeck Inc. a discount rate of 11.8% (11.6% in 2010) was used. For the Falck Group, a discount rate of 10.7% has been used for emergency, assistance and healthcare activities, while a discount rate of 12% was used for training services. For the ALK Group, a discount factor of 12% was used (11% in 2010). The discount rate is before tax, and the result of [WACC/(1 – tax rate)] and the applied cash flows are also pre-tax figures.

Impairment of other intangible assets In 2011, Lundbeck wrote down patent rights and other rights by a total of DKK 142 million. The impairment loss is recognised in the income statement under cost of sales in the amount of DKK 31 million, under administrative expenses in the amount of DKK 5 million and under research and development costs in the amount of DKK 106 million. The recoverable amount was calculated on the basis of management’s re-assessed estimate of the value in use of the assets. In 2010, impairment of product rights amounted to DKK 48 million, which was recognised in the income statement under distribution costs. The recoverable amount was calculated on the basis of management’s re-assessed estimate of the value in use of the assets.

Sale of product rights In 2011, Lundbeck sold the product rights to Nembutal®, Cogentin® and Diuril®. No gain from the sale of these product rights was recognised in 2011 because any gain is subject to developments in revenue from these products at the buyer, which Lundbeck does not control. The fair value of the deferred gain is based on management’s estimate. Recognition of any gain will commence at the time when revenue from the three products exceeds the carrying amount of the product rights at the time of disposal.

60

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 10 - 11 10. INTANGIBLE ASSETS, CONTINUED

Patent

Product

and license

Other Projects

intangible

in

Goodwill rights rights assets progress Total

DKKm DKKm DKKm DKKm DKKm DKKm

Cost at 1 January 2010

4,006

4,059

583

1,236

81

9,965

239

243

2

7

(1)

490

Reclassification

37

(37)

-

29

2

31

Addition through acquisitions

35

-

108

-

-

143

Additions

-

305

114

103

Disposals

-

-

(10)

(44)

(58)

4,317

4,570

683

1,342

127

11,039 (1,693)

Currency translation

Cost at 31 December 2010 Amortisation and impairment at 1 January 2010, adjusted

-

(19)

(507)

(331)

(836)

-

Currency translation

-

(10)

-

-

-

Reclassification

-

-

-

Amortisation

-

(414)

Impairment

-

(48)

Amortisation and impairment on disposals

-

-

Amortisation and impairment at 31 December 2010

(19)

(979)

522 (112)

(10)

(7)

-

(7)

(155)

-

(608)

-

-

-

(48)

10

35

-

45

-

(2,321)

(39)

(360)

(963)

Carrying amount at 31 December 2010

4,298

3,591

323

379

127

8,718

Carrying amount at 31 December 2009

3,987

3,552

252

400

81

8,272

11. PROPERTY, PLANT AND EQUIPMENT

Other fixtures Prepayments

Land and

buildings

Plant and machinery

and fittings, tools and

Leasehold

and other assets under

equipment improvements construction

Total

DKKm DKKm DKKm DKKm DKKm DKKm

Cost at 1 January 2011

4,472

2,024

1,211

-

637

8,344

Currency translation

17

14

2

1

4

38

Reclassification

16

13

3

-

(33)

712

-

891

60

Additions through acquisitions

-

(1) 1,663

Additions

167

152

185

8

409

Disposals

(165)

(45)

(216)

(7)

(229)

Cost at 31 December 2011

5,219

2,158

2,076

62

788

10,303

(1,687)

(1,481)

(908)

-

-

(4,076)

(18)

(13)

(5)

-

-

(36)

-

1

-

-

-

Depreciation

(198)

(118)

(240)

(7)

-

(563)

Impairment for the year

(271)

(5)

(15)

-

-

(291)

135

39

186

3

-

363

(2,039)

(1,577)

(982)

-

(4,602)

Depreciation and impairment at 1 January 2011 Currency translation Reclassification

Depreciation and impairment on disposals Depreciation and impairment at 31 December 2011

(4)

921 (662)

1

Carrying amount at 31 December 2011

3,180

581

1,094

58

788

5,701

Carrying amount at 31 December 2010

2,785

543

303

-

637

4,268

156

208

In the carrying amount at 31 December 2011, financial leasing is included in the amount of

40

12

Carrying amount of mortgage-backed land and buildings

669

11

CONSOLIDATED FINANCIAL STATEMENTS

680

61


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 11 - 12 11. PROPERTY, PLANT AND EQUIPMENT, CONTINUED

Other fixtures Prepayments

Land and

buildings

Plant and

and fittings, tools and

and other assets under

machinery equipment construction

Total

DKKm DKKm DKKm DKKm DKKm Cost at 1 January 2010

4,213

1,956

1,242

496

Currency translation

39

34

13

8

94

Reclassification

15

8

14

(68)

(31)

-

7,907

Additions through acquisitions

13

3

2

Additions

211

61

54

Disposals

(19)

(38)

(114)

(93)

(264)

Cost at 31 December 2010

4,472

2,024

1,211

637

8,344

294

18 620

Depreciation and impairment at 1 January 2010

(1,504)

(1,343)

(891)

-

Currency translation

(11)

(25)

(9)

-

Reclassification

1

6

Depreciation

(184)

(146)

Depreciation and impairment on disposals

11

105

-

143

Depreciation and impairment at 31 December 2010

(1,687)

(1,481)

(908)

-

(4,076)

Carrying amount at 31 December 2010

2,785

543

303

637

4,268

Carrying amount at 31 December 2009

2,709

613

351

496

4,169

financial leasing is included in the amount of

23

107

130

Carrying amount of mortgage-backed land and buildings

170

27

- (113)

(3,738) (45)

-

7

-

(443)

In the carrying amount at 31 December 2010,

170

12. INVESTMENTS IN ASSOCIATES 2011 DKKm Cost at 1 January

-

Additions

2,850

Additions through acquisitions

14

Reclassification

(2,850)

Adjustment regarding prior-year acquisitions

2

Cost at 31 December

16

Value adjustments and impairment at 1 January

-

Share of profit for the year after tax before special items

100

Share of special items

(69)

Share of other comprehensive income

(18)

Share of other changes in equity

(3)

Reversed impairment on disposals

(11)

Accumulated value adjustments and impairment at 31 December

(1)

Carrying amount at 31 December 2011

15

On 14 January 2011, the Group acquired 36% of the share capital of Falck A/S. In July 2011, the shares were contributed to Falck Holding A/S, and at the same time Falck Holding A/S acquired additional shares in Falck A/S, to the effect that Falck Holding A/S owns 98.8% of the share capital of Falck A/S. At the same occasion, the Group subscribed for additional shares and reached an ownership interest of 57.4% of the share capital of Falck Holding A/S. Falck Holding A/S was consolidated in the Group as a subsidiary from 1 July 2011.

62

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 12 - 13 12. INVESTMENTS IN ASSOCIATES, CONTINUED

In connection with the transition from an associate to a subsidiary, no gains or losses were realised. Note 29: Business combinations, provides more

information.

Please see the group overview for information about registered office and ownership interests in associates.

2011/31

December 2011

DKKm

Summarised financial data for associates Revenue

23

Profit for the year

-

Total assets 320 Total liabilities 320

13. FINANCIAL ASSETS AND FINANCIAL RISKS The Group's financial investments classified as financial assets at fair value through profit or loss primarily relate to Lundbeckfond Invest A/S' investments. These investments are made on the basis of an investment policy approved by the Board of Directors. The strategy aims for an appropriate diversification of investments on different asset classes and geographical markets in order to achieve an appropriate diversification of interest rate, exchange rate, credit and equity risks on the financial investments. The purpose is to reduce the risk of losses but also to retain the prospect of gaining a long-term return on the invest-

ments.

Credit risks Credit risks concerning the Group's financial investments primarily relate to investment in bonds and other unlisted investments funds investing in loans to businesses. In order to limit the credit risk, a large proportion of this asset class has been invested in Danish government and mortgage bonds with a high credit rating. To achieve a higher return, the Group also invests in corporate bonds.

Equity risks Equity risks concerns the Group's holding of listed and unlisted shares, including private equity funds as part of the Group's investment operations. Most of these investments are placed in listed shares.

To limit the risk of losses on these shares, they are diversified on different geographical regions and sectors in accordance with the applicable investment policy. Derivative financial instruments may be used to manage the equity risk.

Other things being equal, a 10% drop in equity prices would reduce profits by DKK 473 million (2010: DKK 507 million). For further information on risks concerning the Group's financial investments, see note 18: Cash resources and note 30: Financial risks and financial instru-

ments.

CONSOLIDATED FINANCIAL STATEMENTS

63


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 13 13. FINANCIAL ASSETS AND FINANCIAL RISKS, CONTINUED

Financial assets at fair value Available through for-sale

profit or

financial

Other

loss assets receivables DKKm DKKm DKKm Carrying amount at 1 January 2011

10,444

21

Reclassification to securities, current assets, 1 January 2011

(442)

-

85 -

Carrying amount at 1 January 2011, adjusted

10,002

21

85

Additions

5,939

81

Disposals

(6,098)

(11)

Value adjustments, year-end

(363)

(2)

1

Reclassification to securities, current assets

304

-

-

Carrying amount at 31 December 2011

9,784

89

87 67

15 (14)

Carrying amount at 1 January 2010

11,572

26

Reclassification to securities, current assets, 1 January 2010

(1,050)

-

-

Carrying amount at 1 January 2010, adjusted

10,522

26

67

Additions

6,042

Disposals

(7,945)

(4)

-

28

Value adjustments, year-end

775

(1)

1

Reclassification to securities, current assets

608

-

-

Carrying amount at 31 December 2010

10,002

21

85

(11)

Fair value hierarchy for financial assets and financial liabilities, measured at fair value Level 1 includes financial assets for which the fair value is measured on the basis of quoted prices (unadjusted) in active markets for identical assets. Level 2 includes financial assets and financial liabilities for which the fair value is measured on the basis of directly or indirectly observable inputs other than the quoted prices included in level 1. Level 3 includes financial assets for which the fair value is measured on the basis of valuation methods which include inputs not based on observable market data.

Financial assets and liabilities measured at fair value

Level 1

Level 2

Level 3

31 December 2011 DKKm DKKm DKKm

Financial assets Financial assets at fair value through profit or loss

Danish mortgage and government bonds

5,704

-

-

Credit bonds

1,029

38

-

Listed equity

3,579

-

-

Property companies

286

-

85

Lundbeckfond Ventures

117

-

150

Private equity funds

36

11

788

Other unlisted funds

39

141

95

Available-for-sale financial assets

65

6

18

Derivatives

-

16

-

Financial assets at fair value

10,855

212

1,136

Financial liabilities Derivatives

-

212

-

Financial liabilities at fair value

-

212

-

64

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 13 - 14 13. FINANCIAL ASSETS AND FINANCIAL RISKS, CONTINUED

Financial assets and liabilities measured at fair value

Level 1

Level 2

Level 3

31 December 2010 DKKm DKKm DKKm

Financial assets Financial assets at fair value through profit or loss

Danish mortgage and government bonds

4,247

-

-

-

Credit bonds

632

37

Listed equity

3,849

-

-

Property companies

317

-

92

Lundbeckfond Ventures

184

-

74

Private equity funds

65

4

733

Other unlisted funds

49

157

57

Available-for-sale financial assets

2

-

19

Derivatives

-

42

-

Financial assets at fair value

9,345

240

975

Financial liabilities Derivatives

-

77

-

Financial liabilities at fair value

-

77

-

2011

2010

DKKm DKKm Financial assets measured at fair value according to level 3 Carrying amount at 1 January

975

637

Additions

240

242

Disposals

(136)

Reclassification, from level 3

1

(1)

Fair value adjustment

56

106

Carrying amount at 31 December

1,136

975

(9)

14. DEFERRED TAX

Temporary differences between the carrying amount and the tax base

Addition

Adjustment of

through

Balance at

Currency

deferred tax,

acquisition

during

Balance at

1 January

translation

1 January

of activities

the year

31 december

Movements

DKKm DKKm DKKm DKKm DKKm DKKm

2011 Non-current assets

3,856

59

89

Current assets

(777)

13

31

32

(10)

(119)

(52)

2

(1)

Tax loss carry-forwards etc.

(821)

(8)

76

(148)

287

(614)

Total

2,238

56

76

3,592

78

6,040

Other Provisions in subsidiaries

3,700 - 40 -

(440)

7,264

14

(719)

182

125

35

(16)

Deferred (tax assets)/tax liabilities Research and development activities (tax credits) Deferred (tax assets)/tax liabilities

609

(11)

(186)

(4)

423

(15)

12 - 12

898 - 898

71

1,579

(1)

(191)

70

1,388

CONSOLIDATED FINANCIAL STATEMENTS

65


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 14 14. DEFERRED TAX, CONTINUED

Addition

Adjustment of

through

Balance at

Currency

deferred tax,

acquisition

during

Balance at

1 January

translation

1 January

of activities

the year

31 December

Movements

DKKm DKKm DKKm DKKm DKKm DKKm

2010 Non-current assets

3,794

141

(10)

100

(169)

3,856

Current assets

(911)

(16)

(7)

16

141

(777)

Other

(68)

(21)

(45)

(31)

3

Tax loss carry-forwards etc.

(444)

(22)

(37)

(318)

(821)

Total

2,340

85

(99)

116

(204)

2,238

712

32

(39)

29

(125)

609

(108)

(9)

(72)

(186)

(197)

423

Provisions in subsidiaries

Deferred (tax assets)/tax liabilities Research and development activities (tax credits) Deferred (tax assets)/tax liabilities

604

23

-

3 (36)

-

166

32

-

(24)

(52)

-

- 29

2011 2010

DKKm DKKm Deferred tax assets concern the following items: Non-current assets

189

34

Current assets

194

151

Provisions and payables

79

147

Other

195

165

Provisions in subsidiaries

15

15

Tax value of tax loss carry-forwards etc.

211

298

Research and development activities (tax credits)

191

186

Offset within legal tax entities and jurisdictions

(591)

(818)

483 178 Deferred tax liabilities concern the following items: Non-current assets

2,175

1,193

Current assets

60

63

Provisions and payables

31

-

Other

183

161

Provisions in subsidiaries

Offset within legal tax entities and jurisdictions

13 (591)

2 (818)

1,871 601

Of the recognised deferred tax assets, DKK 402 million (DKK 484 million in 2010) related to tax losses etc. and research and development activities (tax credits) to be carried forward. Utilisation of these is based on a future positive income that exceeds realisation of the deferred tax liabilities. The recognition of tax losses is based on estimates of the expected earnings and taxable income in the loss-making entities, supported by reports by external analysts, when available.

2011 2010 DKKm DKKm Unrecognised deferred tax assets: Unrecognised deferred tax assets at 1 January

94

92

Currency translation

1

4

Prior-year adjustments

1

7

Additions

261

47

Utilised

(34)

Unrecognised deferred tax assets at 31 December

323

(56) 94

66

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 15 - 16

15. INVENTORIES

2011 2010

DKKm DKKm

Raw materials and consumables

243

Work in progress

480

260 528

Manufactured goods and goods for resale

1,262

1,013

Total

1,985

1,801

Indirect costs of production

346

387

Impairment loss for the year

26

35

Inventories calculated at net realisable value

2

2,377

The total cost of goods sold is included in cost of sales in the amount of

4 2,180

16. TRADE RECEIVABLES AND OTHER RECEIVABLES

2011 2010 DKKm DKKm

Trade receivables Receivables

4,100

2,393

Writedowns

(105)

(27)

Total 3,995 2,366

Due dates of trade receivables Not due

2,976

1,916

Overdue by more than 1 month and up to 6 months

991

375

Overdue by more than 6 month and up to 12 months

63

50

Overdue by more than 12 months

70

52

Total 4,100 2,393

Development in writedowns of trade receivables Writedowns at 1 January

27

Realised writedowns

(42)

36

Reversed, unrealised writedowns

(1)

(1)

Change in writedowns

121

(5)

Writedowns at 31 December

105

27

(3)

Specification of other receivables by due date Not due

697

438

Overdue by up to 3 months

6

25

Overdue by more than 3 month and up to 6 months

4

5

Overdue by more than 6 month and up to 12 months

8

-

Overdue by more than 12 months

1

Total

716

1 469

As no losses are expected on other receivables, no writedowns have been made.

Credit risks The Group's products are sold primarily to distributors of pharmaceuticals and hospitals and services to public authorities, other large customers and small subscription receivables from individual customers. Historically, the losses sustained have been insignificant. This was also the case in 2011. However, the change in writedowns reflects a potentially higher loss in 2012.

The Group has no particular customer concentration and no significant reliance on specific customers. For the Falck Group, the large customers are to a great extent represented by public authorities.

The H. Lundbeck, ALK and Falck groups have all defined internal procedures to be followed in connection with the establishment of new customer relationships and changes to existing relationships. The purpose of these procedures is to ensure that the risk of losses is reduced to the extent possible.

CONSOLIDATED FINANCIAL STATEMENTS

67


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 16 - 17 - 18 16. TRADE RECEIVABLES AND OTHER RECEIVABLES, CONTINUED

At 31 December 2011, receivables from Forest Laboratories, Inc. accounted for more than 5% of total trade receivables. This was also the case at 31 December 2010. At 31 December 2011, receivables from Teva Pharmaceutical Industries Ltd. accounted for more than 5% of total other receivables. This was also the case at 31 December 2010, when receivables from Takeda Pharmaceutical Company Limited also exceeded that limit.

Market risk The pharmaceutical market is characterised by the aim of the authorities to reduce or cap healthcare costs. Market changes such as price reductions may have a considerable impact on the earnings potential of pharmaceuticals.

In 2011, the subsidiaries experienced significant price reductions in several countries in Europe, where higher debts and rising unemployment have compelled the governments to identify savings in the public budgets. These savings have resulted, among other things, in a number of healthcare reforms triggering comprehensive price reductions in a number of countries. The Group expects that the uncertainty about public debts and developments in unemployment and the resulting focus on public budgets will continue into 2012 and 2013. The Group is monitoring developments in the European economies and also developments in trade receivables in order to reduce the risk of losses to the best possible extent.

17. INCOME TAX

2011 2010 DKKm DKKm Income tax payable/(income tax receivable) at 1 January

(124)

Currency translation

8

(62)

Tax payable through acquisition

72

-

Prior-year tax adjustments

11

49

Tax payable on profit for the year

1,084

1,165

Tax on other comprehensive income

(32)

(51)

Tax paid for the year

(989)

(1,177)

Tax paid/received in respect of prior years

80

Income tax payable/(income tax receivable) at 31 December

110

3

(51) (124)

Income tax is specified as follows: Income tax receivable

(134)

Income tax payable

244

(261) 137

Income tax payable/(income tax receivable)

110

(124)

18. CASH RESOURCES

2011 2010 DKKm DKKm

Fixed-term deposits

1,680

Other cash resources

2,305

4,491 1,299

Cash at 31 December

3,985

5,790

Securities with a maturity of less than 3 months

744

133

Securities with a maturity of more than 3 months

1,571

363

Securities at 31 December

2,315

496

Cash and securities at 31 December

6,300

6,286

DKK 95 million of the Group's cash and securities is held by a Swedish subsidiary comprised by Swedish insurance rules and, by extension, governed by rules on solvency requirements.

The securities portfolio is classified as financial assets measured at fair value through profit or loss.

68

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 18 - 19 - 20 18. CASH RESOURCES, CONTINUED

Liquidity and credit risk and capital structure With the present capital structure, the Group is well-consolidated. The Group aims to retain adequate cash resources to support business development and flexibility in case of changes to the market situation, potential acquisition activities and product in-licensing opportunities. This is achieved through a combination of liquidity management, ultra-liquid assets and guaranteed and unguaranteed credit facilities. The capital structure is considered appropriate relative to the Group's strategic plans. The credit risk of cash and derivatives (forward exchange contracts, currency options and interest-rate options) is limited because Lundbeck deals only with banks with a high credit rating. To further limit the risk of losses, internal limits have been defined for the credit exposure accepted towards the banks with which the Group collaborates, and the Group aims to maintain counterparty diversification to avoid material concentration at individual counterparties. The Group also uses collateral agreements (e.g. ISDA and GRMA) and exchange of collateral with counterparties with which the Group has hedging business. Certain of the Falck Group’s loans, including the debt of Falck Holding A/S, are subject to certain loan covenants, and the Falck Group continuously monitors whether the covenants are observed. 19. ASSETS HELD FOR SALE Falck has resolved to divest the subsidiary that provides emergency services in Brazil because the company has resolved, going forward, to focus on the private and commercial market as a foundation for growth in Brazil. Consequently, the investment in the company has been written down to fair value less expected costs to sell. On 17 February 2012, an agreement was reached for a sale of the company. The sale will not affect the profit for the 2012 financial year. 2011 2010 DKKm DKKm Assets and liabilities concerning assets held for sale may be specified in the following main groups: Receivables

92

Other non-current assets

6

-

Total assets held for sale

98

-

Non-current liabilities

23

-

Current liabilities

75

-

Total liabilities relating to assets held for sale

98

-

-

20. CAPITAL BASE The Foundation's capital base is DKK 2,225,000. The present charter of the Foundation was approved by the Board of Directors on 30 May 2011. The Civil Affairs Agency acts as supervisory authority. Of the Foundation's profit before tax less non-distributed dividends in the subsidiaries and associates, at least 20% must first be allocated to the capital base.

2011 2010 DKKm DKKm Change in capital base during the period 1 July 2005 - 31 December 2011

The capital base at 1 January 2005 amounted to:

1,420

2005 Capital base increased by

80

80

2006 Capital base increased by

150

150 100

1,420

2007 Capital base increased by

100

2009 Capital base increased by

150

150

2010 Capital base increased by

150

150

2011 Capital base increased by

175

-

Capital base at 31 December

2,225

2,050

Grants, net

498

383

CONSOLIDATED FINANCIAL STATEMENTS

69


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 21 - 22 - 23

21. OTHER RESERVES

2011 2010 DKKm DKKm

Currency translation reserve Balance at 1 January

(291)

(796)

Currency translation for the year concerning foreign subsidiaries and additions to net investments in foreign subsidiaries

243

564

Tax in relation hereto

(46)

(59)

Balance at 31 December

(94)

(291)

Hedging reserve Balance at 1 January

(5)

Adjustment, deferred exchange gains/losses, hedging, recognised in other comprehensive income

64

Exchange gains/losses, hedging, transferred to revenue

45 (214)

(126)

151

Exchange gains/losses, trading, transferred to net financials (transferred from hedging)

-

1

Value adjustment of interest hedging instruments

(56)

-

Repayment of interest hedging instruments

15

-

Tax in relation hereto

26

12

Balance at 31 December

(82)

(5)

Reserve for fair value adjustment of available-for-sale financial assets Fair value adjustment at 1 January

2

6

Fair value adjustment

(2)

(1)

Realised gain on disposal

(7)

(3)

Prolonged impairment losses recognised in the income statement.

3

-

Fair value adjustment at 31 December

(4)

2

Total other reserves

(180)

(294)

22. MINORITY INTERESTS 2011 2010 DKKm DKK m Minority interests at 1 January

4,571

Share of profit/loss for the year

815

817

Share of other comprehensive income for the year

28

148

Share of other capital movements

12

10

Dividend

(252)

(211)

Addition on acquisition of Falck

(1,329)

-

Buyback of shares from minority interests

(52)

(18)

Increase in minority interests

2

-

Adjustment of provision for acquisition of minority interests

(14)

Minority interests at 31 December

3,781

3,825

4,571

23. PENSIONS AND SIMILAR OBLIGATIONS

The majority of the employees of the Group are covered by pension plans paid for by the companies of the Group. The types of plan vary according to regulatory requirements, tax rules and economic conditions in the countries in which the employees are employed. A summary of the most important plans is given below.

Defined contribution plans For defined contribution plans, the employer undertakes to pay a defined contribution (e.g. a fixed amount or a fixed percentage of the pay). Under a defined contribution plan, the employees will usually bear the risk related to future developments in interest and inflation rates, mortality and disability etc.

70

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 23 23. PENSIONS AND SIMILAR OBLIGATIONS, CONTINUED

The cost of defined contribution plans, representing contributions to the plans, totalled DKK 373 million in 2011 (DKK 234 million in 2010).

Defined benefit plans For defined benefit plans, the employer undertakes to pay a defined benefit (e.g. a retirement pension at a fixed amount or a fixed percentage of the employee’s final salary). Under a defined benefit plan, the company usually bears the risk relating to future developments in interest and inflation rates etc. For defined benefit plans, the present value of future benefits, which the company is liable to pay under the plan, is computed using actuarial principles. The computation of present value is based on assumptions about discount rates, changes in pay rates and pensions, investment yield, staff resignation rates, mortality, disability and other factors. Present value is computed exclusively for the benefits to which the employees have earned entitlement through their employment with the company. Actuarial gains and losses are recognised in the income statement as they are calculated.

2011 2010

DKKm DKKm

Pensions and similar obligations Present value of funded pension obligations

345

283

Fair value of plan assets

(279)

(233)

Funded pension obligations, net

66

50

190

186

Provisions for pensions, 31 December

256

236

Other pension-like obligations

105

92

Provisions for pensions and pension-like obligations, 31 December

361

328

Present value of unfunded pension obligations

Pension obligations and similar obligations break down as follows: Non-current obligations

342

Current obligations

19

316 12

Pension obligations and similar obligations, 31 December

361

328

The actuarial assumptions applied in calculating pension obligations concerning the defined benefit plans vary from one country to the next and are based on local economic and social conditions. The following assumptions were applied:

2011 2010

Discount rate

2.7%-8.0%

2.7%-8.5%

Pay rate increase

2.0%-5.5%

2.0%-5.5% 1.3%-3.3%

Pension increase

1.3%-2.9%

Age-weighted staff resignation rate

0%-8%

0%-8%

Expected return on plan assets

2.5%-8.0%

2.5%-8.5%

2011 2010 % distribution % distribution The fair value of the plan assets breaks down as follows: Shares

9

10

33

27

Bonds

Property

4

3

Insurance contracts

52

60

Other assets

2

1

Total

100

100

CONSOLIDATED FINANCIAL STATEMENTS

71


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 23 23. PENSIONS AND SIMILAR OBLIGATIONS, CONTINUED

2011 2010 DKKm DKKm

Change in present value of funded pension obligations Present value of funded pension obligations at 1 January

283

Addition through acquisitions

24

232 6

Currency translation

8

18

Pension expenses

12

8

Interest expenses relating to the obligations

15

12

Actuarial (gains)/losses

10

7

Disbursements

(6)

(6) -

Employee contributions

2

Settlement

(3)

-

New plan

-

6

Present value of funded pension obligations at 31 December

345

283

Change in fair value of plan assets Fair value of plan assets 1 January

233

Addition through acquisitions

26

6

6

15

12

9

Currency translation

Expected return on plan assets

191

Actuarial (gains)/losses

(3)

1

Payments

16

11

Disbursements

(10)

(6)

Employee contributions

2

2

Settlement

(3)

-

New plan

-

4

Fair value of plan assets 31 December

279

233

Realised return on plan assets

6

11

Change in present value of unfunded pension obligations Present value of unfunded pension obligations at 1 January

186

Pension expenses

7

7

Interest expenses relating to the obligations

7

9

Actuarial (gains)/losses

(7)

15

Disbursements

(3)

(4)

190

186

Present value of unfunded pension obligations at 31 December

159

Change in obligations concerning defined benefit plan Pension obligations at 1 January

236

200

Currency translation

2

3

Addition through acquisitions

(2)

-

Recognised as expense (change recognised in the income statement)

35

50

Payments

(16)

(11)

Disbursements

1

Employee contributions

-

Pension obligations at 31 December

256

(4) (2) 236

Specification of change recognised in the income statement Pension expenses

19

Interest expenses relating to the obligations

22

15 21

Expected return on plan assets

(12)

(9)

Actuarial (gains)/losses

21

6

New plan

-

2

Total expenses recognised

35

50

72

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 23 - 24 23. PENSIONS AND SIMILAR OBLIGATIONS, CONTINUED

Other pension-like obligations An obligation of DKK 105 million (2010: DKK 92 million) is recognised in the Group to cover other pension-like obligations, including primarily termination benefits in a number of subsidiaries. The benefit payments are conditional upon specified requirements being met. The amount of pension-like obligations increased by DKK 13 million in 2011 (declined by DKK 4 million in 2010).

24. LIABILITIES RELATING TO ACQUISITIONS AND MINORITY INTERESTS

2011 DKKm

Liabilities concerning acquisition of minorities

516

Payable considerations and contingent consideration

39

Liabilities 31 December 555 Non-current portion: Liabilities concerning acquisition of minorities

493

Payable considerations and contingent consideration

19

512

Current portion: Liabilities concerning acquisition of minorities

23

Payable considerations and contingent consideration

20

43

Liabilities concerning acquisition of minorities Liabilities 1 January

-

Currency translation

43

Additions through acquisitions

438

Addition on acquisition of minority interests

(1)

Interest component, discounted liabilities

2

Adjustment, recognised goodwill

1

Adjustment, recognised in equity

33

Liabilities concerning acquisition of minorities 31 December

516

Due dates in respect of acquisition of minorities are expected to be: Within 1 year of the balance sheet date

23

Between 1 and 5 years from the balance sheet date

374

More than 5 years after the balance sheet date

119

Liabilities concerning acquisition of minorities 31 December

516

Payable considerations and contingent consideration Liabilities 1 January

-

Additions through acquisitions 39 Payable considerations and contingent consideration 31 December

39

Due dates in respect of acquisition of minorities are expected to be: Within 1 year of the balance sheet date

20

Between 1 and 5 years from the balance sheet date

19

More than 5 years after the balance sheet date

-

Payable considerations and contingent consideration 31 December

39

CONSOLIDATED FINANCIAL STATEMENTS

73


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 25 - 26

25. OTHER PROVISIONS

2011 2010

DKKm DKKm

Other provisions at 1 January

496

463

Currency translation

4

18

Additions through acquisitions

33

-

Provisions charged

51

106

Provisions used

(152)

(79)

Unused provisions reversed

(24)

(12)

408

496

Other provisions at 31 December break down as follows: Non-current provisions

191

280

Current provisions

217

216

408 496

Other provisions primarily cover H. Lundbeck A/S' expenses for defending the company's intellectual property rights and returns and the guarantees and commitments towards buyers which ALK-Abell贸 A/S has undertaken in connection with the divestment of the ingredients business, Chr. Hansen in 2005.

26. MORTGAGE, BANK, LEASING AND REPO DEBT

2011 2010 DKKm DKKm

Mortgage debt Mortgage debt by maturity:

Within 1 year of the balance sheet date

1

Between 1 and 5 years from the balance sheet date

7

6

More than 5 years after the balance sheet date

2,255

1,879

Mortgage debt at 31 December

2,263

1,886

1

Specification of mortgage debt: Non-current liabilities

2,262

Current liabilities

1

1,885 1

Mortgage debt at 31 December

2,263

1,886

Weighted average Amortised

Currency/

Fixed/

effective

costs

Nominal value

Fair value

Expiry floating interest rate DKKm DKKm DKKm

Mortgage debt 2011 Bond loan, H. Lundbeck

DKK/2035

Floating

2.4%

1,411

1,540

1,581

Bond loan, H. Lundbeck

DKK/2037

Floating

1.9%

437

440

420

Bond loan, H. Lundbeck

DKK/2034

Floating

1.5%

10

10

10

Bond loan, H. Lundbeck

DKK/2034

Floating

1.5%

2

2

2

Bond loan, Falck

DKK/2025 Fixed until 2015

4.5%

377

409

415

Bond loan, ALK

DKK/2028

4.0%

26

26

26

Total

2,263

2,427

2,454

Fixed

74

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 26 26. MORTGAGE, BANK, LEASING AND REPO DEBT, CONTINUED

Weighted average Amortised

Currency/

Fixed/

effective

costs

Nominal value

Fair value

Expiry floating interest rate DKKm DKKm DKKm

Mortgage debt 2010 Bond loan, H. Lundbeck

DKK/2035

Floating

3.4%

1,410

1,567

1,528

Bond loan, H. Lundbeck

DKK/2037

Floating

2.0%

436

440

422

Bond loan, H. Lundbeck

DKK/2034

Floating

1.6%

10

10

10

Bond loan, H. Lundbeck

DKK/2034

Floating

1.6%

2

2

2

Bond loan, ALK

DKK/2025

Fixed

4.3%

28

28

28

Total

1,886

2,047

1,990

2011 2010 DKKm DKKm

Bank and leasing debt Bank and leasing debt by maturity:

Within 1 year of the balance sheet date

283

10

Between 1 and 5 years from the balance sheet date

1,772

9

More than 5 years after the balance sheet date

4,371

1

Bank debt at 31 December

6,426

20

Specification of bank and leasing debt: Long-term obligations, loan

6,088

-

Long-term obligations, leased assets

55

10

Total long-term

6,143

10

Short-term obligations, loan

257

7

Short-term obligations, leased assets

26

3

Total short-term

283

10

Bank debt at 31 December

6,426

20

Weighted average Nominal Fixed/ effective value 2011

Currency

Expiry

floating

interest rate

DKKm

Floating

4.2%

6,048

DKK, EUR, NOK, Bank debt, Falck Group

USD, SEK, BRL

2012-2018

Leasing debt, Falck Group

EUR, BLR,

COP, NOK, USD

2012-2016

Floating

7,.%

70

2014-2016

Floating

3.5%

11

2016

Fixed

3.1%

297

Leasing debt, ALK Group

EUR

EUR, USD,

Other bank and finance loans, ALK Group

DKK, NOK

6,426

2010 Leasing debt

EUR

2016

Floating

3.5%

13

0%-2.6%

7

EUR, USD,

Other bank and finance loans

DKK, NOK

2011-2014

Floating

20

Repo debt Repo debt in the Lundbeck Foundation of DKK 98 million falls due on 16 and 19 January 2012 The debt carries a fixed rate of interest from the date of conclusion at 0.67%.

CONSOLIDATED FINANCIAL STATEMENTS

75


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 27 - 28 - 29

27. ADJUSTMENTS

2011 2010 DKKm DKKm

Depreciation, amortisation and impairment

1,508

1,132

Incentive programmes

33

26

Change in pension obligation

25

Change in other provisions

Other adjustments

25

1,489

21

(102)

40 (26) 1,193

28. WORKING CAPITAL CHANGES

2011 2010 DKKm DKKm Change in inventories

(113)

79

Change in receivables

(344)

(171)

Change in receivables from associates

(22)

-

Change in current liabilities

502

198

23 106 29. BUSINESS COMBINATIONS

2011 In July 2011, the Lundbeck Foundation acquired controlling influence in Falck Holding A/S through the contribution of the Foundation's holding of Falck A/S shares and the subscription of new shares in Falck Holding A/S. At the same time, Falck Holding A/S acquired additional shares in Falck A/S and now owns 98.8% of Falck A/S and the Falck Group. The investment is consistent with the Foundation's intention to expand its healthcare activities.

In August 2011, the Falck Group acquired all the shares in Colombian ambulance service provider SER, which operates in three large cities in Colombia and has a large network of doctors. In addition, in September 2011 the Falck Group acquired all the shares in German company Kranken-Transport Herzig, which operates ambulance services in the German state of North Rhine Westphalia. These acquisitions should be seen as part of the Falck Group's aim to become a global and leading player within their business areas.

Name

Principal activity

Date of acquisition

Ownership interest acquired

Voting share acquired

Emergency, Assistance,

July 2011

57.36%

57.36%

Falck Holding A/S

Healthcare and

Training activities

Servicio Emergencias

Ambulance services

August 2011

100%

100%

Regional (SER)

Kranken-Transport Herzig

Ambulance services

September 2011

100%

100%

The transactions were accounted for using the purchase method of accounting.

76

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 29 29. BUSINESS COMBINATIONS, CONTINUED

Calculation of acquired net assets and cash consideration: Fair value on

Fair value on

acquisition

acquisition of other

of Falck

enterprises

Total 2011

DKKm DKKm DKKm 2011 Intangible assets

100

-

100

1,643

20

1,663

Property, plant and equipment

Cash and cash equivalents

969

11

980

Other current assets

1,887

19

1,906

Interest-bearing debt

(4,478)

(9)

(4,487)

Current liabilities, provisions etc.

(3,622)

(7)

(3,629)

Minority interests

1,329

(3)

1,326

31

(2,141) 5,245

Acquired net assets

(2,172)

Goodwill

5,173

72

Other intangible assets

3,206

25

Deferred tax on intangible assets

(812)

(6)

Acquisition cost

5,395

122

5,517

Acquired cash in hand and at bank

(969)

(11)

(980)

Cash consideration Expensed transaction costs

3,231 (818)

4,426

111

4,537

24

27

51

On the acquisition of the Falck Group, an assessment was made of the value of the acquired customer agreements, framework agreements and customer portfolios. The valuation thereof was based on the �Multi Period Excess Earnings Method (MEEM-method)� in which the value is calculated on the basis of an expected future cash flow. The principal assumptions are expected lives of the existing agreements and portfolios, earnings and contribution for using associated assets and employees.

The valuation of the brand is based on the Relief from royalty method in which the value is calculated on the basis of an expected future cash flow with the key assumptions being expected life, royalty rate and growth rates and a theoretically calculated tax effect. Since the brand is expected to be upheld indefinitely, the useful life has been set as non-definable.

2010 The ALK Group acquired the share capital of the Dutch companies Artu Biologicals (Artu Biologicals Europe B.V. and Artu Biologicals Onroerend Goed B.V.) from Fornix Biosciences with a view to currently strengthening the ALK Group's global presence and enhance its market consolidation. The acquisition was completed in the ALK Group's Dutch subsidiary effective 1 July 2010, and the two companies are being integrated in an ongoing process.

The ALK Group also acquired the allergy vaccine activities of US company Nelco Laboratories with a view to currently strengthening the ALK Group's global presence. The acquisition was completed in the ALK Group's US subsidiary effective 1 August 2010. Nelco Laboratories manufactures and sells injection-based allergy vaccines in the USA.

Name

Principal activity

Date of acquisition

Ownership interest acquired

Voting share acquired

Artu Biologicals

Production and sale

1 July 2010

100%

100%

of allergy vaccines

Nelco Laboratories

Sale of allergy vaccines

1 August 2010

100%

100%

The transactions were accounted for using the purchase method of accounting.

CONSOLIDATED FINANCIAL STATEMENTS

77


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 29 29. BUSINESS COMBINATIONS, CONTINUED

Calculation of acquired net assets and cash consideration:

2010

DKKm Fair value on acquisition Land and buildings Plant and machinery

13

3

Other plant and equipment

2

Other intangible assets

108

Inventories

33

Receivables

24

Current liabilities

(40)

Acquired net assets 143 Goodwill

35

Acquisition cost

178

Acquired cash in hand and at bank

-

Cash consideration 178 The cost price paid in connection with the company acquisitions exceeded the fair value of acquired identifiable assets, liabilities and contingent liabilities. According to a preliminary calculation, the positive difference amounts to DKK 7,658 million (2010: DKK 35 million). The difference with respect to the acquisition of the Falck Group represents the value of acquired contractual customer relationships, logo and brand in the amount of DKK 2,394 million after tax. In addition, individual small assets and liabilities with a net value of DKK 36 million have been identified and recognised. The remaining difference of DKK 5,173 million represents goodwill attributable to the four different business areas in the Falck Group, and it is mainly based on the realisation of the strategic goal of the Foundation of having a third leg with future growth opportunities and the value of the acquired staff. The difference with respect to the acquisition of other companies represents the value of acquired contractual customer relationships in the amount of DKK 19 million after tax. The remaining difference of DKK 72 million represents goodwill.

Acquired assets include trade receivables at a fair value of DKK 1,116 million. The contractual gross receivable amounts to DKK 1,234 million, of which DKK 118 million was assessed as being irrecoverable at the acquisition date.

The ownership of the Falck Group was acquired in two steps, the first of which was in January 2011, when the Foundation achieved an ownership interest of 36%, and the second in July 2011, after which time the ownership is 57%. No gain or loss has been recognised in connection with the step acquisition of the shareholding majority of Falck because no material changes to the valuation of the Falck Group were made between the two acquisition dates. Business combinations may be adjusted for up to 12 months after the date of acquisition.

The difference in respect of Artu Biologicals and Nelco Laboratories represents the value of assets whose fair value cannot be reliably measured, future growth opportunities and the value of the acquired staff.

Of the Group's comprehensive income in 2011 of DKK 2,522 million (2010: DKK 4,161 million), DKK 28 million (2010: DKK 2 million) is attributable to results generated by the acquired operations after the acquisition date.

Revenue and comprehensive income for the year for the Group in 2011 calculated pro forma as if the acquired enterprises had been acquired on 1 January 2011 amount to DKK 28,731 million (2010: DKK 16,940 million) and DKK 2,920 million (2010: DKK 4,197 million), respectively. The amounts stated are exclusive of the effect of the purchase price allocation, which is incorporated in the pre-acquisition balance sheet. 2012 At the beginning of 2012, the Falck Group acquired 75% of VL Transport Sanitari S.L.U. and Group VL Serveis Santaries S.L.U., which operate ambulance services in Catalonia, Spain, for a cash consideration of DKK 108 million. The Falck Group will use the acquisition as a platform for further expansion in ambulance services in the Spanish market.

Name

Principal activity

Date of acquisition

Ownership interest acquired

Voting share acquired

VL Transport Sanitari S.L.U

Ambulance services

February 2012

75%

75%

Group VL Serveis Sanitaris,

Ambulance services

February 2012

75%

75%

S.L.U. (VL)

Because of the acquisition date, it has not been possible to complete a purchase price allocation.

78

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30

30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS

The Group's business activities imply that the results and balance sheet may be affected by various financial risks. The management of these risks is decentralised and handled respectively in the H. Lundbeck, ALK and Falck groups and in Lundbeckfond Invest A/S based on policies and guidelines approved by the Board of Directors. See also note 13: Financial assets and financial risks, note 16: Trade receivables and other receivables, and note 18: Cash resources for a description of risks and the management thereof. 30.1 Exchange rate risks Exchange rate risks arise because the Group's expenses and income in different currencies do not match and because the Group's assets and liabilities denominated in foreign currency do not balance, among other things due to Lundbeckfond Invest A/S' investment assets. The management of these risks is focused on risk mitigation. The Group applies various derivative financial instruments to manage these risks. Some of these instruments are classified as hedging instruments and meet the accounting criteria for hedging future cash flows. Changes in the fair value of these contracts are recognised in the statement of comprehensive income under other comprehensive income as they arise and – on invoicing of the hedged cash flow – transferred from other comprehensive income for inclusion in the same item as the hedged cash flow. Hedging contracts that do not meet the hedge criteria are classified as trading contracts, and changes in the fair value are recognised as financial items as they arise. The need for hedging is assessed separately in the H. Lundbeck, ALK and Falck groups and in Lundbeckfond Invest A/S.

Other things being equal, an increase of 5% in the USD would increase the Group's profit by DKK 79 million.

2011 2010 Monetary assets and monetary liabilities for the principal currencies at 31 December

DKKm

DKKm

Monetary assets CAD

171

113

CHF

279

334

GBP

786

663

JPY

108

236

TRY

103

128

USD

3,061

2,110

Monetary liabilities CAD

182

CHF

19

15

GBP

136

90

JPY

100

-

TRY

21

26

1,517

1,535

USD

68

Due to the long-standing fixed exchange rate policy in Denmark, the foreign currency risk for EUR is considered immaterial, and EUR is therefore not included in the list above.

Estimated impact on profit and equity from a 5% increase in year-end exchange rates of the most important currencies

CAD CHF GBP JPY TRY USD DKKm DKKm DKKm DKKm DKKm DKKm

2011 Profit Equity

(2)

10

(5)

0

1

79

(28)

3

(6)

0

(2)

394

2010 Profit Equity The profit impact is included in the impact on equity.

1

15

23

12

(15)

9

23

12

CONSOLIDATED FINANCIAL STATEMENTS

2

70

(4)

313

79


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

Currency translation in associates measured using the equity method.

2011

2010

DKKm DKKm

-

(2)

Transferred to the income statement in connection with divestment of shareholding interest

Currency translation at 1 January

-

2

Currency translation at 31 December

-

-

30.2 Interest rate risk Interest rate risk relates to the Group's interest-bearing assets and liabilities and principally to the Group's bonds classified as financial assets measured at fair value through profit or loss. See note 13: Other financial assets and the Falck Group's overall loan financing, cf. note 26: Mortgage, bank, leasing and repo debt.

Interest receivable The duration of the investments when selecting financing and investment instruments is used to manage the interest rate risk. In addition, the Group uses derivative financial instruments to mitigate the interest rate exposure. The use of financial instruments to manage interest rate risk does not qualify for hedge accounting, and the changes in fair value are therefore recognised as financial income or expenses in an ongoing process.

The Group's portfolio of bonds has a duration of 1.0 year. Other things being equal, an increase of 1%-point in interest rates would increase the Group's profit by DKK 66 million.

At 31 December 2011, the Group had an interest rate swap for managing interest rate exposure on portfolio investments. Other than this, there were no derivatives at 31 December 2011 and 31 December 2010 to manage interest rate risks because the distribution of investments carrying floating and fixed interest at the given times was deemed to be satisfactory.

Interest expenses The Falck Group’s interest rate risk is mainly affected by the Falck Group’s overall financing. Based on the current market situation, the Falck Group's executive management and board of directors have resolved to convert 70% of the overall financing to a fixed three-year interest rate using interest rate swaps. The remainder of the overall financing is based on a short-term interest rate. For hedging interest rate risks, interest rate swaps ensure that the interest rate for part of the debt raised in DKK cannot exceed 1.4%, that interest rates on debt raised in EUR cannot exceed 1.17% and that interest rates on debt raised in USD cannot exceed 0.55%. The remaining part of the syndicated financing must be based on a short-term interest rate. The Falck Group is therefore sensitive to fluctuations in market interest rates, and a fluctuation by 1%-point would change the annual interest expense by DKK 20 million as a large part of the interest rate exposure is hedged using interest rate swaps. Without this hedge, a fluctuation by 1%-point would change the Group's interest expense by DKK 62 million. The sensitivity stated has been determined based on the recognised financial assets and liabilities at 31 December 2011. No adjustment has been made for servicing and raising of debt, or the like in 2011. Furthermore, it is assumed that all hedges of floating-rate loans are deemed to be effective. 30.3 Maturity dates for financial assets and financial liabilities 31 December 2011

Less than

Between

Financial assets

1 year

1 and 5 years

More than 5 years

Total

Effective interest

DKKm DKKm DKKm DKKm rates Derivatives included in the trading portfolio

4

-

-

4

Securities 1)

Danish mortgage and government bonds

2,295

1,096

2,351

5,742

0-6%

Credit bonds

1

323

704

1,028

3-35%

Listed equity

-

-

3,580

3,580

-

Shares in property companies

-

-

371

371

-

Lundbeckfond Ventures

-

-

267

267

-

Private equity funds

-

-

853

853

-

Other unlisted funds

-

-

257

257

-

8,383

12,102

-

Financial assets at fair value through profit or loss Derivatives to hedge future cash flows

2,300

1,419

-

12

-

-

12

-

Financial assets used as hedging instruments

12

-

-

12

-

80

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

31 December 2011

Less than

Between

Financial assets

1 year

1 and 5 years

More than 5 years

Total

Effective interest

DKKm DKKm DKKm DKKm rates Receivables 2)

4,883

Fixed-term deposits

1,680

Other cash resources

2,305

Loans and receivables

8,868

Available-for-sale financial assets Total financial assets

- 11,180

53 - - 53 89 1,561

35 - - 35 - 8,418

4,971

-

1,680

0-8%

2,305

0-8%

8,956

-

89

-

21,159

-

Financial liabilities

82

-

-

82

-

Financial liabilities at fair value through profit or loss

Derivatives included in the trading portfolio

82

-

-

82

-

Derivatives to hedge future cash flows and net investment in foreign subsidiaries

89

41

-

130

-

Financial liabilities used as hedging instruments

89

41

-

130

-

Mortgage, bank, leasing and repo debt

463

1,711

6,612

8,786

1-8%

Employee bonds/purchase obligations

56

469

119

644

3-6%

Other payables and non-disbursed grants 2)

6,714

394

7,108

-

Financial liabilities, measured at amortised cost

7,233

2,574

6,731

-

16,538

-

Total financial liabilities

7,404

2,615

6,731

16,750

-

31 December 2010

Less than

Between

Financial assets

1 year

1 and 5 years

More than 5 years

Total

Effective interest

DKKm DKKm DKKm DKKm rates Derivatives included in the trading portfolio

1

-

-

1

Securities 1)

Danish mortgage and government bonds

488

1,163

2,632

4,283

0-5%

Credit bonds

-

472

633

2-19%

Listed equity

-

-

3,849

3,849

-

Shares in property companies

-

-

409

409

-

Lundbeckfond Ventures

-

-

258

258

-

Private equity funds

-

-

802

802

-

Other unlisted funds

Financial assets at fair value through profit or loss

Derivatives to hedge future cash flows

- 489

161

- 1,324

263

263

-

8,685

10,498

-

42

-

-

42

-

Financial assets used as hedging instruments

42

-

-

42

-

Receivables 2)

3,052

Fixed-term deposits

4,491

Other cash resources

1,299

Loans and receivables

8,842

Available-for-sale financial assets Total financial assets

- 9,373

60 - - 60 21 1,405

26 - - 26 - 8,711

3,138

-

4,491

0-4%

1,299

0-6%

8,928

-

21

-

19,489

-

CONSOLIDATED FINANCIAL STATEMENTS

81


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

Less than

Between

1 year

1 and 5 years

More than 5 years

Total

Effective interest

DKKm DKKm DKKm DKKm rates

Financial liabilities

15

-

-

15

-

Financial liabilities at fair value through profit or loss

Derivatives included in the trading portfolio

15

-

-

15

-

62

-

-

62

-

Financial liabilities used as hedging instruments

62

-

-

62

-

Derivative financial instruments to hedge future cash flows

Mortgage, bank, leasing and repo debt

Employee bonds

Other payables and non-disbursed grants 2)

308

15

-

60

1,880 -

2,203

1-4%

60

3-6% -

4,170

310

3

4,483

Financial liabilities, measured at amortised cost

4,478

385

1,883

6,746

-

Total financial liabilities

4,555

385

1,883

6,823

-

1) The securities are classified as financial assets measured at fair value through profit or loss.

The amounts in the table above are exclusive of interest.

2) Including receivables and payments recognised in non-current assets and liabilities

3) Nominal value of mortgage debt falling due after more than 5 years totals DKK 2,427 million at 31 December 2011 (2010: DKK 2,047 million)

30.4 Net outstanding forward exchange transactions, currency options and interest rate swaps

Exchange Exchange Average

Contractual

gains/losses

gains/losses

hedge prices

value in

recognised

recognised

of existing

accordance

in other

in income

with hedge comprehensive

accounting

income

forward

statement/

exchange

balance sheet

transactions

Expiry

Forward contracts DKKm DKKm DKKm DKK period 2011 AUD

5

-

-

539.84

May 2012

CAD

552

(19)

5

536.25

Dec. 2012 Dec. 2012

CHF

183

1

(12)

610.84

CZK

22

1

-

30.38

Sep. 2012

GBP

577

(15)

(1)

859.70

Dec. 2012

HUF

4

-

-

2.48

Mar. 2012

JPY

121

(5)

(19)

7.08

Dec. 2012

MXN

108

2

3

41.39

Dec. 2012

NOK

339

(3)

-

94.76

Nov. 2012

PLN

118

(1)

-

165.25

Oct. 2012

RUB

49

-

-

17.41

Oct. 2012

SEK

338

(10)

(1)

80.77

Oct. 2012

SGD

4

-

(1)

426.56

Aug. 2012

TRY

148

(2)

20

290.70

Sep. 2012

USD

457

(15)

113

550.15

Dec. 2012

ZAR

48

-

1

69.35

Oct. 2012

Forward contracts 2011

3,073

(66)

108

82

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

Exchange Exchange Average

Contractual

gains/losses

gains/losses

hedge prices

value in

recognised

recognised

of existing

accordance

in other

in income

with hedge comprehensive

accounting

income

forward

statement/

exchange

balance sheet

transactions

Expiry

Forward contracts DKKm DKKm DKKm DKK period

2010 AUD

15

-

(13)

429.11

May 2011

CAD

367

(4)

(38)

548.19

Dec. 2011

CHF

131

(10)

(12)

545.31

Dec. 2011

CZK

21

-

(1)

29.74

Oct. 2011

EUR

411

-

5

746.46

Apr. 2011

GBP

103

-

-

861.61

Nov. 2011

HUF

8

-

-

2.66

Aug. 2011

ILS

3

-

(2)

145.87

Feb. 2011

JPY

20

-

6

6.72

Aug. 2011

MXN

115

(3)

2

44.10

Dec. 2011

NOK

-

-

(2)

PLN

22

-

(2)

182.95

RUB

40

-

1

18.24

Nov. 2011

SEK

36

(1)

1

79.51

Dec. 2011

SGD

21

-

6

418.53

May 2011

TRY

161

3

(28)

357.30

Sep. 2011

USD

1,587

14

(76)

566.72

Dec. 2011

ZAR

52

(4)

(9)

73.71

Nov. 2011

Forward contracts 2010

3,113

(5)

-

Aug. 2011

(162)

Exchange Exchange

Contractual

gains/losses

value in

recognised

gains/losses

accordance

in other

with hedge comprehensive

accounting

income

balance sheet

prices 1)

Currency options (zero cost options)

DKKm

DKKm

DKKm

DKK

recognised in income statement/

Average exercise Expiry period

2011 JPY/DKK (JPY put bought)

-

-

JPY/DKK (JPY call sold)

-

-

-

-

19

Currency options

19

2010 JPY/DKK (JPY put bought)

177

-

JPY/DKK (JPY call sold)

180

-

(1)

-

(1)

Currency options

-

6.45

Jan. 2011

6.53

Jan. 2011

1) The average exercise price for the sold call option has an average kick-in price of DKK 7.18.

At 31 December 2010, currency options concerning hedging of a milestone payment in JPY 2011. At 31 December 2011, the exchange difference between the contract value and the market value of the concluded forward exchange contracts and currency options represented a loss of DKK 77 million (a loss of DKK 21 million in 2010), of which DKK 11 million was recognised in the income statement (DKK 16 million in 2010).

CONSOLIDATED FINANCIAL STATEMENTS

83


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

Interest rate

gains/losses

recognised

in other

Contractual comprehensive

Fixed

value

income

interest rate

Expiry

Interest rate collar/interest rate swap

DKKm

DKKm

%

period

2011 DKK interest rate swap

2,300

USD interest rate swap

431

EUR interest rate swap

1,487

(38) - (3)

Interest rate collar/interest rate swap

1.40

Aug. 2014

0.55

Aug. 2014

1.17

Aug. 2014

(41)

Trading part

Average Exchange hedge prices gains/losses of existing recognised forward

Contractual

in the income

value

exchange

statement transactions

Expiry

Forward contracts DKKm DKKm DKK period

2011

-

8

Forward contracts

USD

-

8

-

-

2010 GBP

USD

600

-

(55)

(1)

-

Forward contracts

600

(55)

561.92

Jan. 2011

Exchange gains/losses recognised Average

Contractual

in the income

value statement

exercise prices

Expiry

Currency options DKKm DKKm DKK period

2011 EUR/DKK (EUR put bought)

597

3

746.25

EUR/DKK (EUR call sold)

1,194

(1)

746.66

Oct. 2011

JPY/DKK (JPY call bought)

100

1

7.00

May 2012

JPY/DKK (JPY put sold)

100

(3)

7.55

May 2012

Currency options

Oct. 2011

-

2010 EUR/DKK (EUR put bought)

448

1

746.25

Oct. 2011

EUR/DKK (EUR call sold)

896

(1)

746.66

Oct. 2011

Currency options

-

84

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 30 - 31 30. FINANCIAL RISKS AND FINANCIAL INSTRUMENTS, CONTINUED

Interest rate gains/losses recognised

Contractual

in the income

Fixed

value

statement

interest rate

Interest rate swap

DKKm

DKKm

%

Expiry period

2011 Fixed to floating

600

Interest rate swap

(74)

3.47

May 2020

(74)

2010 Fixed to floating

600

Interest rate swap

(9)

3.47

May 2020

(9)

Deferred recognition of hedging transactions recognised in other comprehensive income

2011

2010

DKKm DKKm Deferred gains/losses on hedging transactions at 1 January

(5)

34

Adjustment, deferred exchange gains/losses, hedging, recognised in other comprehensive income

49

(162)

Exchange gains/losses, hedging, transferred to revenue

(81)

97

Exchange gains/losses, hedging, transferred to prepayments from Forest (balance sheet)

(14)

25

Exchange gains/losses, trading, transferred to net financials (transferred from hedging)

Value adjustment of interest hedging instruments

Repayment of interest hedging instruments

11

-

Deferred gains/losses on hedging transactions at 31 December

(82)

(5)

- (42)

1 -

31. CONTRACTUAL OBLIGATIONS 2011 2010

DKKm DKKm The Group has signed operating lease obligations for a total amount of

2,491

587

Payment of the obligations breaks down as follows: Less than 1 year

474

183

Between 1 and 5 years

1,063

349

More than 5 years

954

55

2,491 587 Expensed lease payments amounted to

406

200

The operating lease commitments primarily concern the Falck Group's leases for vehicles and buildings. The lease term for vehicles typically runs for 4-9 years. The lease term for buildings typically runs for 20 years.

The Group has signed finance lease obligations for a total amount of

86

14

Payment of the finance lease obligations breaks down as follows: Less than 1 year

29

3

Between 1 and 5 years

48

10

More than 5 years

9

1

86

14

Present value of finance lease obligations

80

13

CONSOLIDATED FINANCIAL STATEMENTS

85


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 31 - 32 31. CONTRACTUAL OBLIGATIONS, CONTINUED

Financial lease arrangements comprise leases on buildings, vehicles and other lease arrangements.

Other than the above, the Group has made the following contractual obligations:

Lundbeck Foundation and Lundbeckfond Invest A/S The Lundbeck Foundation and Lundbeckfond Invest A/S have capital contribution obligations amounting to DKK 676 million (2010: DKK 662 million).

H. Lundbeck Group Other purchase obligations The H. Lundbeck Group has undertaken to purchase property, plant and equipment in the amount of DKK 318 million (2010: DKK 251 million). Research collaborations The H. Lundbeck Group is part of multi-year research and development collaborations comprising minimum research and contractual obligations in the order of DKK 126 million (2010: DKK 0 million).

The total amount of the obligations may increase substantially in line with the favourable development of the collaborations. Other contractual commitments The H. Lundbeck Group has entered into various service agreements amounting to DKK 80 million (2010: DKK 76 million).

ALK Group The ALK Group's financial obligations in respect of research and development projects amounted to DKK 3 million (2010: DKK 4 million).

Falck Group Falck Holding A/S has a purchase option on part of the buildings at a predetermined value. At the end of the year, Falck Holding A/S informed the owner that it intends to exercise the purchase option in 2012. The property has a value of DKK 68 million.

32. GUARANTEES AND CONTINGENT LIABILITIES The Group has the following warranty commitments and contingent liabilities:

Joint taxation H. Lundbeck A/S, ALK-Abelló A/S and Falck Holding A/S and their Danish subsidiaries are pooled for tax purposes with Lundbeckfond Invest A/S. The companies under this joint taxation scheme are separately liable for the payment of own taxes until these have been settled with the administration company (Lundbeckfond Invest A/S). After such time, Lundbeckfond Invest A/S is liable for the combined taxes under the joint taxation scheme.

H. Lundbeck Group Forest Prepayments from Forest have been translated at the exchange rate at the transaction date or at the forward rate and recognised in the balance sheet in the amount of DKK 234 million (2010: DKK 517 million). If the translation had been made at the exchange rate at the balance sheet date, the prepayments would have amounted to DKK 286 million (2010: DKK 493 million). Bank guarantees and letters of intent The H. Lundbeck Group’s bankers have issued bank guarantees to third parties in the amount of DKK 136 million (2010: DKK 117 million). In 2010, the group had issued a guarantee to a third party in the amount of DKK 9 million. The Group has assessed that the fair value of guarantees is DKK 0 (2010: DKK 0). Pending legal proceedings The H. Lundbeck Group is involved in legal proceedings in a number of countries against a number of businesses, including patent disputes. In the opinion of H. Lundbeck A/S, the outcome of these proceedings will not have a material impact on the Group’s financial position, results of operations or cash flows

86

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 32 32. GUARANTEES AND CONTINGENT LIABILITIES, CONTINUED

beyond the amount provided for in the financial statements. Due to uncertainty about the outcome of the legal proceedings, the amount of the provision is uncertain. The H. Lundbeck Group is also involved in a case filed by the United States Federal Trade Commission (FTC) in respect of the pricing of NeoProfen®, which is marketed by Lundbeck Inc. in the USA. In September 2010, the U.S. Federal District court ruled in favour of Lundbeck. FTC and the State of Minnesota appealed the ruling. In August 2011, Lundbeck also won the appeal. In January 2012, H. Lundbeck received a statement from the chairman of FTC that they do not intend to seek review by the US Supreme Court of the appeal case. However, legal possibilities exist for appeal until 20 February 2012. H. Lundbeck A/S had not announced a final decision at the date of publication of its financial statements. In 2010, the European Commission opened a formal investigation to examine whether H. Lundbeck by way of unilateral behaviour and/or agreements has violated EU competition law and thereby hindered a lawful entry of generic citalopram into markets in the European Economic Area (EEA). In 2011, H. Lundbeck complied with a number of ‘Requests for Information’ from the Commission. In December 2011, the Brazilian antitrust authorities (Secretariat of Economic Law –SDE) initiated administrative proceedings to investigate whether H. Lundbeck’s enforcement of data protection rights could be viewed as anticompetitive conduct. In January 2012, H. Lundbeck submitted a response to the authorities. Industry obligations The H. Lundbeck Group has return obligations normal for the industry. H. Lundbeck A/S' management expects no major loss on these obligations.

ALK Group

Guarantee and collaterals commitments Guarantee and collaterals commitments amounted to DKK 9 million (2010: DKK 10 million).

Collaterals The carrying amount of land and buildings provided as collateral for credit institutions amounted to DKK 162 million (2010: DKK 170 million).

Contingent liabilities and assets The management of ALK-Abelló A/S assesses that the outcome of pending claims and other disputes will not have a material impact on the group’s financial position. In connection with the divestment of the ingredients business, Chr. Hansen in 2004/05, ALK-Abelló A/S has undertaken the usual representations and warranties towards the buyer. The representations and warranties expire successively over the coming years. A provision of DKK 140 million (2010: DKK 140 million) has been recognised to cover specific risks. ALK-Abelló A/S and Chr. Hansen A/S are jointly and severally liable for the combined income tax payable for the period until 31 August 2005. At 31 August 2005, the jointly-taxed companies had no current tax liability.

Falck Group

Guarantee and collaterals commitments Guarantee and collaterals commitments amounted to DKK 9 million. The Falck Group has issued performance bonds to a certain extent in connection with a number of contracts, including performance bonds for a total of DKK 249 million provided in connection with ambulance contracts in Denmark.

As part of the group's activities, usual supplier agreements have been entered into and certain letters of intent signed. In connection with the divestment of companies and operations, usual representations and warranties are made. There are currently no outstanding claims which are not sufficiently recognised in the balance sheet.

Contingent liabilities and assets The Falck Group is a party to certain litigation and claims. Management believes that rulings in this respect will not have a material impact on the group’s financial position.

CONSOLIDATED FINANCIAL STATEMENTS

87


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 32 - 33 32. GUARANTEES AND CONTINGENT LIABILITIES, CONTINUED

Collaterals The shares in the subsidiary Falck A/S and Falck Danmark A/S have been provided as collateral for debt in the Falck Group.

The carrying amount of property, plant and equipment provided as collateral for debt to credit institutions amounted to DKK 518 million. Issued mortgage deeds amounted to DKK 380 million.

Lundbeck Foundation and Lundbeckfond Invest A/S Collaterals Bonds in repo transactions have been provided as collateral for repo debt, and other bonds have been provided as collateral for hedging transactions. The value of bonds provided as collateral at 31 December 2011 amounted to DKK 180 million (2010: DKK 341 million). 33. RELATED PARTIES The Lundbeck Foundation is an industrial foundation established by Grete Lundbeck in 1954.

Related parties exercising a significant influence on the Lundbeck Foundation: * The company’s Executive Management and Board of Directors

* Companies in which the company's Executive Management and Board of Directors exercise a significant influence

The following transactions were made between related parties and the Lundbeck Foundation, all on an arm's length basis: • The Board of Directors and the Executive Management received remuneration. See note 3.

• In connection with the acquisition of shares in Falck A/S and Falck Holdings A/S´ acquisition of shares in Falck A/S, a small amount of the shares were acquired from board members in the amount of DKK 8 million.

• Transactions with associates:

Related parties of the Falck Group also comprise associates in which the company exercises significant influence. Reference is made to note 12 and the group overview for an overview of associates.

2011 DKKm Transactions with associates: Disposal of property, plant and equipment

28

Acquisition of services

10

Sale of services

1

Rental costs 9 Receivables from associates appear from the balance sheet, and interest payable for the period amounted to DKK 0.

• Other than the above and except for transactions eliminated in the consolidated financial statements, there have only been few transactions of immaterial importance with related parties.

34. EVENTS AFTER THE BALANCE SHEET DATE

No material events have occurred subsequent to the balance sheet date.

88

CONSOLIDATED FINANCIAL STATEMENTS


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

COUNTRY

OWNERSHIP

Datterselskaber Lundbeckfond Invest A/S

Denmark

100%

H. Lundbeck A/S

Denmark

70%

Falck Holding A/S

Denmark

57%

ALK-Abelló A/S

Denmark

40% (67% of the votes)

Associates Obel-LFI Ejendomme A/S

Denmark

50%

Veloxis Pharmaceuticals A/S

Denmark

31%

17%

Direct investments

United Kingdom

Asante Solutions Inc.

Acacia Pharma

USA

Bonesupport Holding AB DBV Technologies

6%

Sweden

11%

France

18%

EpiTherapeutics ApS

Denmark

13%

Nexstim Oy

Finland

8%

Syntaxin Ltd

United Kingdom

10%

H. Lundbeck Group Lundbeck Argentina S.A.

Argentina

100%

Lundbeck Australia Pty Ltd.

Australia

100%

Australia

100%

Belgium

100%

Lundbeck Brasil Ltda.

Brazil

100%

Lundbeck Canada Inc.

Canada

100%

Chile

100%

Lundbeck Colombia S.A.S.

Colombia

100%

Lundbeck China Holding A/S

Denmark

67%

China

100%

China

100%

- CNS Pharma Pty Ltd.

Lundbeck S.A.

Lundbeck Chile Farmacéutica Ltda.

- Lundbeck Pharmaceuticals (Tianjin) Co., Ltd.

- Lundbeck Pharmaceuticals Consulting (Shanghai) Co., Ltd.

Lundbeck Cognitive Therapeutics A/S

Denmark

100%

Lundbeck Export A/S

Denmark

100%

Lundbeck Insurance A/S

Denmark

100%

Lundbeck Pharma A/S

Denmark

100%

United Kingdom

100%

Lundbeck Group Ltd. (Holding)

- Lundbeck Limited

United Kingdom

100%

- Lundbeck Pharmaceuticals Ltd.

United Kingdom

100%

- Lifehealth Limited

United Kingdom

100%

- Lundbeck UK LLP

United Kingdom

100%

Lundbeck Eesti A/S

Estonia

100%

OY H. Lundbeck AB

Finland

100%

Lundbeck SAS

France

100%

Sofipharm SA

France

100%

France

100%

- Laboratoire Elaiapharm SA

Lundbeck Hellas S.A.

Greece

100%

Lundbeck B.V.

The Netherlands

100%

India

100%

Lundbeck India Private Limited Lundbeck (Ireland) Ltd. Lundbeck Israel Ltd.

Ireland

100%

Israel

100%

Lundbeck Italia S.p.A.

Italy

100%

Lundbeck Pharmaceuticals, Italia S.p.A.

Italy

100%

- Archid S.a.

Luxembourg

100%

Lundbeck Japan K. K.

Japan

100%

Lundbeck (Beijing) Pharmaceuticals Consulting Co., Ltd.

China

100%

Lundbeck Korea Co., Ltd.

Korea

100%

Croatia

100%

Lundbeck Croatia d.o.o.

CONSOLIDATED FINANCIAL STATEMENTS

89


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

SIA Lundbeck Latvia

COUNTRY

OWNERSHIP

Latvia

100%

UAB Lundbeck Lietuva

Lithuania

100%

Mexico

100%

New Zealand

100%

Lundbeck México, SA de CV Lundbeck New Zealand Limited H. Lundbeck AS

Norway

100%

- CNS Pharma AS

Norway

100%

Lundbeck Pakistan (Private) Limited

Pakistan

100%

Lundbeck America Central S.A.

Panama

100%

Poland

100%

Portugal

100%

Lundbeck Poland Sp.z.o.o. Lundbeck Portugal - Produtos Farmacêuticos Unipessoal Lda. Lundbeck RUS OOO

Russia

Lundbeck (Schweiz) AG

Switzerland

100%

Lundbeck Pharmaceutical GmbH

Switzerland

100%

Lundbeck Singapore PTE. LTD.

Singapore

100%

100%

Lundbeck Slovensko s.r.o.

Slovakia

100%

Lundbeck Pharma d.o.o.

Slovenia

100%

Spain

100%

Lundbeck España S.A.

Spain

100%

Axofarma Lab, S.A. H. Lundbeck AB

Sweden

100%

- CNS Pharma AB

Sweden

100%

Lundbeck South Africa (Pty) Limited

South Africa

Lundbeck Czech Republic s.r.o.

Czech Republic

Lundbeck İlaç Ticaret Limited Şirketi

100% 100%

Turkey

100%

Germany

100%

Lundbeck Hungária KFT

Hungary

100%

Lundbeck USA Holding, Inc. 1)

USA

100%

- Lundbeck Inc. 2)

USA

100%

- Lundbeck Pharmaceuticals Ireland Limited

Ireland

100%

- Lundbeck Pharmaceuticals Services, LLC

USA

100%

- Lundbeck Research USA, Inc.

USA

100%

Lundbeck GmbH

Lundbeck de Venezuela, C.A.

Venezuela

100%

Austria

100%

1) At 1 January 2012, the subsidiary was renamed Lundbeck USA LLC

2) At 1 January 2012, the subsidiary was renamed Lundbeck LLC.

Lundbeck Austria GmbH

ALK Group ALK-Abelló Nordic A/S

Denmark

100%

ALK-Abelló Nordic A/S (filial)

Sweden

100%

ALK-Abelló Nordic A/S (filial)

Norway

100%

ALK-Abelló Nordic A/S (filial)

Finland

100%

United Kingdom

100%

France

100%

ALK-Abelló Ltd.

ALK-Abelló S.A.

ALK-Abelló Arzneimittel GmbH

Germany

100%

ThemoCARE GmbH

Germany

100%

ALK-Abelló Allergie-Service GmbH

Austria

100% 100%

ALK-Abelló AG

Switzerland

ALK AG

Switzerland

ALK-Abelló B.V.

The Netherlands

100% 100%

- Artu Biologicals Europe B.V.

The Netherlands

100%

- Artu Biologicals Onroerend Goed B.V.

The Netherlands

100%

ALK-Abelló S.A.

Spain

ALK-Abelló S.p.A.

Italy

100%

ALK-Abelló sp. z.o.o.

Poland

100%

ALK-Abelló, Inc.

USA

100%

USA

100%

- ALK-Abelló, Source Materials, Inc. ALK-Abelló Pharmaceuticals, Inc. ALK-Abelló A/S (filial)

90

CONSOLIDATED FINANCIAL STATEMENTS

100%

Canada

100%

China

100%


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

COUNTRY

OWNERSHIP

Falck Group Falck A/S

Denmark

99%

- Falck Danmark A/S

Denmark

100%

- Falck Health Care Holding A/S

Denmark

100%

- Falck Health Care A/S

Denmark

100%

Denmark

100%

- ActivCare A/S

Denmark

100%

Denmark

100%

- Ulfab Danmark A/S

Denmark

100%

- Vikteam A/S

Denmark

80%

- Falck Hjælpemidler A/S

Denmark

92%

- Falck JobService A/S

Denmark

85%

- Falck Hjemmepleje A/S

Denmark

100%

Denmark

100%

- North Securities A/S

- HealthCare Danmark ApS

- ActivCare Privat A/S

- Lone Hovmand Sundhedsafdeling A/S

Denmark

49%

- Falck Norge Holding AS

Norway

100%

- Falck Redning AS

Norway

100%

Norway

100%

- Falck Emergency AS

Norway

100%

Norway

100%

- Falck Norge Leasing AS

Norway

100%

- Falck Health Care Norge AS

Norway

100%

- Falck Sevices AS

Norway

100%

- Falck Nutec Holding A/S

Denmark

100%

- Falck Nutec Esbjerg A/S

Denmark

100%

- Falck Nutec Management A/S

Denmark

100%

- Falck Global Safety B.V.

The Netherlands

100%

- Falck Nutec AS

- Falck Nutec Ltd.

- Stor Oslo Service AS - Falck Ambulanse AS

Norway

100%

United Kingdom

100%

- Nutec Centre for Safety Ltd. 1)

United Kingdom

100%

- Falck Onsite Limited

United Kingdom

100%

- Onsite Training Services Limited 1)

United Kingdom

100%

- Falck Nutec Trinidad and Tobago Limited

- Nutec UK Ltd.

Trinidad & Tobago

80%

United Kingdom

100%

- Nutec Belgium Holding BVBA 1)

Belgium

100%

Belgium

100%

- Falck Nutec B.V.

The Netherlands

100%

The Netherlands

100%

- Nutec Belgium BVBA 1)

- MSTS Asia Sdn. Bhd.

- Marinesafety International Rotterdam B.V.

Malaysia

70%

- Risktec (M) Sdn. Bhd.

Malaysia

100%

- Falck Bestari Healthcare Sdn Bhd.

Malaysia

82%

- MSTS Asia (S'pore) Pte. Ltd.

Singapore

100%

The Netherlands

100%

- Falck Bedrijfshulpverlening B.V.

- Falck Prime Atlantic Limited

- Falck caspian Safe LLC

Nigeria

51%

Azerbaijan

65%

- Falck Nutec Brasil Participacoes Ltda

Brazil

100%

Brazil

100%

- Southfield Ltd

Thailand

50%

Thailand

65%

- Falck Nutec Nigeria Limited

- Falck Nutec Brasil Treinamentos em Segurança Marítima Ltda - Falck Nutec (Thailand) Ltd

Nigeria

51%

- Falck USA Holdings, Inc

USA

100%

- Falck Alford Holdings, Inc

USA

80%

- Alford Services, Inc

USA

100%

- Alford Safety Services, Inc

USA

100%

- Alford Safety & Compliance, L.L.C.

USA

100%

- Haztec Services - West Indies, L.L.C.

USA

100%

St. Lucia

100%

- Haztec Services St. Lucia Ltd

CONSOLIDATED FINANCIAL STATEMENTS

91


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

COUNTRY

- Falck Alford International B.V.

- Haztec Services Trinidad Limited

- Falck Nutec Vietnam Limited

- Falck Safety Services LLC, De Forenede Arabiske Emirater

- Falck Investment Norge AS

OWNERSHIP

Trinidad & Tobago

100%

The Netherlands

100%

- Falck Alford Holding S.A. de C.V.

Mexico

100%

Mexico

100%

Vietnam

80%

- Falck Alford Training S.A.I.P. de C.V.

United Arab Emirates

49%

Norway

100%

- Falck Followit Norge AS

Norway

100%

- VIFA AB

Sweden

100%

- Falck Sverige Holding AB

Sweden

100%

- Falck Investment Sverige AB

Sweden

100%

- Falck Räddningskär AB

Sweden

100%

- Falck Forsäkrings AB

Sweden

100%

- Falck TravelCare AB

Sweden

100%

- Falck Ambulans AB

Sweden

100%

- Falck Räddningstjänst AB

Sweden

100%

- Falck Services AB

Sweden

100%

- Svensk Sjöambulans AB 2)

Sweden

50%

- Ulfab Sairaankuljetus OY

Finland

100%

- S Reg Holding A/S

Denmark

100%

- S Reg AB

Sweden

100%

- S Reg Service AB

Sweden

100%

- S Reg A/S

Denmark

100%

- S Reg Oy

Finland

100%

- S Reg AS

Norway

100%

- Falck USA, Inc.

USA

100%

- FCA Corp.

USA

87%

USA

100%

- Care Ambulance Service, Inc.

- Falck EMS Corp.

USA

95%

- Lifestar Response Corporation, Inc.

USA

100%

- Lifestar Response of Alabama, Inc.

USA

100%

- Medibus, Inc.

USA

100%

- STAT Equipment Corp.

USA

100%

USA

51%

- Bi-County Ambulance & Ambulette Transport Services Corp.

USA

100%

- Lifestar Response of New Jersey, Inc.

USA

100%

- Lifestar Response of Maryland, Inc.

USA

100%

- Access Transport Services Holding, Inc.

USA

100%

USA

100%

- Home Care Equipment, Inc.

USA

100%

USA

100%

- Falck Southeast Corp.

USA

100%

- Falck Health Care Sverige Holding AB

Sweden

100%

- FalckAM Health Care AB

Sweden

100%

- Falck Health Care AM A/S

Denmark

100%

- Falck Aktiv Arbetsmedicin AB

Sweden

100%

Sweden

100%

- Falck Investments Finland Oy Ab

Finland

100%

- Falck Finland Oy

Finland

100%

- Falck Oy

Finland

100%

Estonia

100%

- Falck Benelux NV

Belgium

93%

- Ambuce Rescue Team BVBA

Belgium

100%

- Ambuce Limburg BVBA

Belgium

100%

- MDV International BVBA

Belgium

100%

- Falck Investments NV

Belgium

80%

92

- STAT EMS, LLC

- Access on Time Language Services LLC - Robinson's Ambulance & Oxygen Service, Inc.

- Falck Healthcare AB

- Falck Autoabi OÜ

- Falck Medical Services LLC

United Arab Emirates

CONSOLIDATED FINANCIAL STATEMENTS

49%


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

- Falck Eurasia B.V.

- Beijing Falck Rescue Consulting Services Co., Ltd

- Falck Kazakhstan LLP

- Falck Fire Services Rus LLC

- Falck Foundation VZW

COUNTRY

OWNERSHIP

The Netherlands

95%

China

100%

Kazakhstan

100%

Russia

100%

Belgium

100%

- Falck Medycyna Sp.z o.o.

Poland

100%

Poland

75%

- Falck SK a.s.

Slovakia

93%

- Falck Emergency AS

Slovakia

51%

- Falck Záchranná a.s.

Slovakia

100%

Slovakia

100%

- La Salus, a.s.

Slovakia

100%

Slovakia

100%

- Falck Fire Services a.s.

Slovakia

100%

- Falck CZ a.s.

Czech Republic

93%

- Lainsa Servicios Contra Incendios, S.A.

- Falck France SAS

- Starowka sp zo.o.

- Falck Academy s.r.o. - La Salus Phrama s.r.o.

Spain

51%

France

100%

- Falck AVD Holding B.V.

The Netherlands

100%

The Netherlands

100% 100%

- Falck AVD B.V.

- Advisebureau van Dijke B.V.

The Netherlands

The Netherlands

100%

- Safety Center Holding B.V.

The Netherlands

100%

- AVD-ICT B.V.

- Safety Center Holland B.V.

The Netherlands

100%

The Netherlands

100%

- Safety Center Zuid Holland B.V.

- Safety Center Colleage c.v.

The Netherlands

51%

- Safety Center Zuid Holland c.v.

The Netherlands

52%

- MIT B.V.

The Netherlands

100%

- Safe Building B.V.

The Netherlands

100%

- Safety Center Team B.V.

The Netherlands

100%

Belgium

100%

- AVD Consultancy N.V.

- Falck Brasil AVD Participações Ltda.

Brazil

100%

- Falck Brasil Plano de Saúde Ltda.

Brazil

100%

- Falck Brasil 747 Participações Ltda.

Brazil

100%

- Toesa Service S.A.

Brazil

60%

Brazil

100%

- Falck Brasil FF Participações Ltda.

Brazil

100%

- Falck Fire & Safety do Brasil S.A.

Brazil

100%

- Falck Panama Holding S.A.

Panama

- EMI Holdings Management S.A.

Panama

63%

- EMI Foreign Holdings 1 S.A.

Panama

100%

- EMI Foreign Holdings 2 S.A.

Panama

100%

- EMI Foreign Holdings 3 S.A.

Panama

100%

- EMI Foreign Holdings 4 S.A.

Panama

100%

- Empresa de Medicina Prepagada - Servicio de Ambulancia Prepagada – Grupo EMI S.A.

Colombia

100%

- EMI El Salvador S.A. de C.V.

El Salvador

100%

- Inversiones EMI Worldwide S.A.

Panama

100%

- EMI Panama S.A.

Panama

100%

- EMI Ecuador S.A.- Emergencia Medica Integral

Ecuador

100%

- Perses S.A.

Uruguay

100%

- Portovenus S.A.

Uruguay

16%

- EMI Venezuela Holding S.A.

Panama

100%

Venezuela

100%

- Centro Medico Integral CEMICA S.A.

Venezuela

100%

- Panamedical Health Systems S.A.

Panama

100%

- Solution Services International Inc.

Panama

100%

- Scandinavian Worldwide Capital Corp.

Panama

100%

- Rheades Business Inc.

Panama

100%

- Tefe Tefe Servicos de Saude Ltda

- Emergencia Medica Integral EMI Centro S.A.

CONSOLIDATED FINANCIAL STATEMENTS

100%

93


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

GROUP OVERVIEW – LUNDBECK FOUNDATION GROUP

At 31 December 2011

COMPANY NAME

- Right Connection Services Corp.

COUNTRY

OWNERSHIP

Panama

100%

Colombia

100%

- Falck Rettungsdienst GmbH

Germany

100%

- Kranken-Transport Herzig GmbH

Germany

100%

Germany

100%

- Falck Österreich GmbH

Austria

100%

- Falck Yardim Hizmetleri Limited Şirketi

Turkey

95%

- Falck UK Limited

United Kingdom

100%

- Servicio Emergencias Regional SER S.A.

- KS-Medi-Service GmbH

- Falck EMS UK Limited

United Kingdom

100%

- Resource Protection International Ltd.

United Kingdom

100%

- Falck India Limited

- Falck Services Limited

United Kingdom

93%

Mauritius

100%

- Falck India Pvt. Ltd.

India

100%

- Falck Services Pvt Ltd.

India

- Falck Fire Services S.R.L

Romania

100% 93%

- Falck Treasury A/S

Denmark

100%

- Investeringsselskabet af 17. december 2007 A/S

Denmark

100%

- Falck Asset Management 9 A/S

Denmark

100%

- Falck DRF Luftambulance A/S

Denmark

51%

- A C Trafik A/S

Denmark

100%

Denmark

100%

- KPC Ejendomme af 6. juni 2002 A/S 2)

- Falck Nederland Holding B.V.

- A C Trafik 2 ApS

1) Dormant company 2) Associate

94

CONSOLIDATED FINANCIAL STATEMENTS

Denmark

25%

The Netherlands

100%


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

PARENT FOUNDATION FINANCIAL STATEMENTS THE LUNDBECK FOUNDATION CONTENTS Income statement for the period 1 January – 31 December Balance sheet at 31 December Notes 1. Accounting policies 2. Financial income and expenses 3. Staff costs 4. Fees to auditors appointed at the general meeting 5. Tax on profit for the year 6. Grants for the year 7. Investments in Lundbeckfond Invest A/S 8. Other securities and investments 9. Statement of changes in equity and capital base 10. Pension obligation 11. Related parties

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION

96 97 98 98 99 100 100 100 1 01 1 01 102 102 102

95


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

INCOME STATEMENT FOR THE PERIOD 1 JANUARY – 31 DECEMBER

2011 2010 Note DKKm DKKm Dividend from Lundbeckfond Invest A/S Financial income Financial expenses Profit from investing activities before costs

7 2 2

682 239 (26) 895

400 136 (6) 530

Staff costs 3 (14) (9) Other external costs 4 (7) (8) Profit before tax 874 513 Tax on profit for the year 5 - Profit for the year 874 513 Proposed distribution of profit: Profit for the year 874 Amount available for distribution 874 The Board of Directors proposes that the profit be allocated as follows: Transferred to capital base

175

Total grants for 2011 504 Reversed grants/repayments (6) Net grants for the year 6 498 Retained earnings 201 Distributed 874

96

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

BALANCE SHEET AT 31 DECEMBER

Assets 2011 2010 Note DKKm DKKm Land and buildings Property, plant and equipment Investments in Lundbeckfond Invest A/S 7 Bond portfolios 8 Unlisted investment funds 8 Financial assets

26 26

27 27

4,046 3,150 18 7,214

4,046 2,633 18 6,697

Non-current assets

7,240

6,724

35 281

29 304

Other receivables Cash

Current assets 316 333 Assets 7,556 7,057

Equity and liabilities Capital base 2,225 Retained earnings 4,290 Equity 9 6,515

2,050 4,089 6,139

Pension obligations 10 Provisions

23 23

20 20

Payable grants, long-term Non-current liabilities

389 389

308 308

Payable grants, short-term Repo debt 8 Other payables Current liabilities

530 97 2 629

416 172 2 590

Liabilities

1,018

898

7,556

7,057

Equity and liabilities Related parties 11

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION

97


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 1 - 2

1. ACCOUNTING POLICIES The annual report of the parent company of the Lundbeck Foundation for 2011 has been prepared in accordance with the provisions of the Danish Financial Statements Act for medium-sized reporting class C enterprises. The annual report is presented in Danish kroner (DKK), which also is the functional currency of the parent company.

The accounting policies are changed from last year. The Investment in the subsidiary Lundbeckfond Invest A/S are now recognised in the balance sheet at cost, and dividends received are recognised in the income statement. The subsidiary was previously recognised in the balance sheet and the income statement according to the equity method. The change of accounting policies is based on a wish to follow international financial reporting pratice in the area. The comparative figures for 2010 have been restated to reflect the new accounting policies. The financial impact on the profit, total assets and equity of the change in accounting policies is described below. The effect of the change in accounting policies for 2010 is as follows: Previous

accounting policies

New accounting

Change

policies

DKKm DKKm DKKm Dividend/profit share Lundbeckfond Invest A/S

2,590

(2,190)

Profit for the year

2,703

(2,190)

400 513

Investment in Lundbeckfond Invest A/S

18,859

(14,813)

4,046

Equity

20,952

(14,813)

6,139

Total assets

21,870

(14,813)

7,057

Changes have also been made to the way in which the income statement and balance sheet are presented, although this has no impact on the profit, total assets and equity.

Consolidated financial statements Consolidated financial statements have been prepared for the Lundbeck Foundation for 2011. The Lundbeck Foundation has not previously prepared consolidated financial statements as the Foundation complies with the exemption conditions set out in section 111(2) of the Danish Financial Statements Act.

Differences relative to the Group’s accounting policies The parent company's accounting policies for recognition and measurement are in accordance with the Group's policies with the exceptions stated below:

Investments in Lundbeckfond Invest A/S Investments in Lundbeckfond Invest A/S are recognised in the Foundation's balance sheet at cost. Dividends are recognised in the income statement.

2. FINANCIAL INCOME AND EXPENSES

2011 2010 DKKm DKKm Financial income Interest income, etc.

107

Gain from securities and other equity investments

132

85 51

239

136

Financial expenses Interest expenses etc.

2

1

Loss on securities and other equity investments

24

5

26 6

98

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 3

3. STAFF COSTS 2011 2010 DKKm DKKm Wages and salaries, incl. holiday allowance

8.8

Pension contributions

0.1

6.7 0.1

4.9

2.6

Pension benefits, including adjustment of pension provision

Other social security costs

0.0

0.0

13.8

9.4

Pension benefits including adjustment of pension provision relates to pension obligations taken over from H. Lundbeck and pension obligations towards for-

mer board members. Remuneration of the Executive Management

2

1

Remuneration of the Board of Directors, including committee fees

2

2

Members of Executive Management and the Board of Directors who also serve as directors in subsidiaries also receive board remuneration directly from such subsidiaries. For a complete description hereof, please see the consolidated financial statements in the annual report of the Lundbeck Foundation for 2011,

Total remuneration of the Executive Management and Board of Directors, including remuneration

2011

2010

received from the wholly owned subsidiary Lundbeckfond Invest A/S is specified as follows:

DKKm

DKKm

Executive Management:

Christian Dyvig, appointed on 1 June 2011

2.2

Board of Directors: Mikael Rørth, Chairman of the Foundation and Lundbeckfond Invest A/S, chairman of the research committee, the biomedical sciences committee and the investment committee

Jørgen Huno Rasmussen, Deputy Chairman of the Foundation, member of the investment committee

0.4

0.8

Thorleif Krarup, deputy chairman of Lundbeckfond Invest A/S, member of the investment committee,

0.5

Kim Klitgaard, employee representative

0.2

Ken Liljegren, employee representative

0.2

Povl Krogsgaard-Larsen, member of the investment, research and the biomedical and natural sciences committees

0.2

Gunhild Waldemar, member of the research committee and the biomedical sciences committee

0.2

Peter Adler Würtzen, employee representative

0.2

Jes Østergaard, chairman of the natural sciences committee and member of the research and investment committees

0.6

Nils Axelsen, stepped down on 30 May 2011

0.2

Mogens Bundgaard-Nielsen, stepped down on 30 May 2011

0.4

Rounding

(0.1)

3.8

2011 2010 Average number of employees during the year

7

6

Number of employees at year-end

7

7

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION

99


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 4 - 5 - 6

4. FEES TO AUDITORS APPOINTED AT THE GENERAL MEETING

2011 2010 DKKm DKKm Other external costs include fees to the company's auditors appointed by the general meeting, Deloitte, in the amount of:

Statutory audit

0.2

0.2

0.2 0.2

5. TAX ON PROFIT FOR THE YEAR

2011 2010 DKKm DKKm

Tax on profit for the year, Lundbeck Foundation

0

0

0

0

In the financial year, the Lundbeck Foundation paid income tax of TDKK 260 (2010: TDKK 166). When calculating taxable income, the Foundation has deducted grants and tax provisions for future grants. No deferred tax is recognised for accounting purposes concerning tax provisions for future grants as this is not expected to crystallise. Deferred tax hereon amounted to DKK 177 million (2010: DKK 227 million).

The Lundbeck Foundation is jointly taxed with Lundbeckfond Invest A/S, which means that the Lundbeck Foundation is taxable on dividends received from Lundbeckfond Invest A/S.

The total income tax payment for the Lundbeck Foundation Group amounted to DKK 909 million (2010: DKK 1,228 million), of which Danish income tax accounted for DKK 468 million (2010: DKK 983 million).

6. GRANTS FOR THE YEAR

2011 2010 Grants for the period can be specified as follows:

DKKm

DKKm 192

Biomedical sciences projects

182

Natural sciences projects

26

28

Fellowships

70

50

Other

21

10

Regular grants

299

280

Grants of Excellence

Centres of Excellence

84

24

Grete Lundbeck European Brain Research Foundation

-

30

Psychiatric research (iPSYCH)

-

50

121

-

Strategic initiatives

205

104

Grants for the year, gross

504

384

Descendants

Reversed grants/repayments

(6)

Grants for the year, net

498

100

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION

-

(1) 383


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 7 - 8

7. INVESTMENTS IN LUNDBECKFOND INVEST A/S DKKm Cost at 1 January 2011

4,046

Cost at 31 December 2011

4,046

Net revaluation at 1 January 2011

14,813

Change in accounting policies, 1 January

(14,813)

Net revaluation at 31 December 2011

-

Carrying amount at 31 December 2011

4,046

Dividend received 2011 682 Carrying amount of equity at 31 December 2011 Lundbeckfond Invest A/S has its registered office in Hellerup and is wholly owned by the Lundbeck Foundation.

13,147

8. OTHER SECURITIES AND INVESTMENTS

Unlisted Bond investment

portfolios

funds

Total

DKKm DKKm DKKm Carrying amount at 1 January 2011

2,633

Additions

3,204

Disposals

(2,795)

(1)

Value adjustments for the year

108

1

109

3,150

18

3,168

Carrying amount at 31 December 2011

18

2,651

-

3,204 (2,796)

Bonds in repo transactions have been provided as collateral for repo debt. The value of bonds in repo transactions provided as collateral at 31 December 2011 amounted to DKK 98 million (2010: DKK 175 million).

Unlisted investment funds include investments in an unlisted investment fund with a residual payment obligation of DKK 6 million (2010: DKK 6 million).

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION

101


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

NOTE 9 - 10 - 11

9. STATEMENT OF CHANGES IN EQUITY AND CAPITAL BASE

Reserve for net revaluation Retained

Capital base*)

of subsidiary

earnings

Total

DKKm DKKm DKKm DKKm Equity at 1 January 2011

2,050

14,813

4,089

20,952

Change in accounting policies, 1 January

-

(14,813)

-

(14,813)

Equity at 1 January 2011 under new accounting policies

2,050

-

4,089

6,139

Grants, net.

(498)

(498)

Retained loss for the year

175

-

699

874

Equity at 31 December 2011

2,225

-

4,290

6,515

*) Changes in capital base 2005-2011:

The capital base at 1 January 2005 amounted to:

2005 Capital base increased by

80

2006 Capital base increased by

150

2007 Capital base increased by

100

2009 Capital base increased by

150

2010 Capital base increased by

2011 Capital base increased by

175

Capital base at 31 December 2011

2,225

1,420

150

10. PENSION OBLIGATIONS

2011 2010 DKKm DKKm Obligations at 1 January

20

Adjustment for the year

3

20 -

Obligations at 31 December

23

20

11. RELATED PARTIES The Lundbeck Foundation defines related parties as the Foundation's Board of Directors and Executive Management, its wholly-owned investment and holding company Lundbeckfond Invest A/S and this company's subsidiaries H. Lundbeck A/S, ALK-Abelló A/S and Falck Holding A/S. Lundbeckfond Invest A/S shares the same address as the Lundbeck Foundation, and there is duality of membership between the Executive Management, administration (partly) and Board of Directors. The Lundbeck Foundation receives dividends from Lundbeckfond Invest A/S. Lundbeckfond Invest A/S pays rent to the Lundbeck Foundation on an arm's length basis. Payments are likewise made for administrative services. For information on remuneration paid to the members of the Executive Management and Board of Directors, please see note 3.

Other than the above, the Lundbeck Foundation has only had immaterial transactions with the related parties.

102

FINANCIAL STATEMENTS – LUNDBECK FOUNDATION


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

THE LUNDBECK FOUNDATION CENTRES OF EXCELLENCE

Neuroscience

The Lundbeck Foundation Center for Membrane- receptors in Neuronal Diseases, MIND

Professor, M.D. Claus Munck Petersen DKK 50 million Professor, Ph.D. Anders Nykjær

The Lundbeck Foundation Center for Integrated Molecular Brain Imaging, CIMBI

Professor, M.D. Gitte Moos Knudsen

DKK 40 million

The Lundbeck Foundation Center for Neurovascular Signaling, LUCENS

Professor, M.D. Jes Olesen

DKK 30 million

Quantum Systems

The Lundbeck Foundation Center for Atomic-scale Materials Design, CAMD

Professor, Dr.h.c. Jens Kehlet Nørskov

DKK 25 million

The Lundbeck Foundation Theoretical Center for Quantum System Research, LTC

Professor, Ph.D. Klaus Mølmer

DKK 20 million

The Lundbeck Foundation Center for Quantum Mechanics for Large Molecular Systems, LCTC

Professor, Dr. Phil. Poul Jørgensen

DKK 20 million

Translational Research

The Lundbeck Foundation Center for Applied Medical Genomics in Personalized Disease Prediction, Prevention and Care, LUCAMP

Professor, M.D. Oluf Borbye Pedersen DKK 60 million

The Lundbeck Foundation Center for Translational Molecular Diagnostics and Bioinformatic Risk Assignment in Common Cancer Diseases, CETAME

Professor, M.D. Torben Ørntoft

DKK 20 million

Copenhagen Prospective Study on Asthma in Childhood – A Lundbeck Foundation center for translational clinical research, COPSAC

Professor, M.D. Hans Bisgaard

DKK 20 million

Clinical Intervention

The Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS

Professor, M.D. Birte Glenthøj

DKK 30 million

The Lundbeck Foundation Center for Interventional Research in Radiation Oncology, CIRRO

Professor, M.D. Jens Overgaard Professor, M.D. Cai Grau

DKK 30 million

The Lundbeck Foundation Center for Fast-Track Hip and Knee Arthroplasty

Professor, M.D. Henrik Kehlet Professor, M.D. Kjeld Søballe

DKK 35 million

Nanoscience

The Lundbeck Foundation Center for Biomembranes Professor, M.D. Ulrik Gether in Nanomedicine, CBN Lektor, Ph.D. Dimitrios Stamou

DKK 34 million

The Lundbeck Foundation Nanomedicine Centre for Individualized Management of Tissue Damage and Regeneration, LUNA

Professor, M.D. Allan Flyvbjerg Professor, Ph.D. Jørgen Kjems

DKK 30 million

Professor, Ph.D. Jan Mollenhauer

DKK 35 million

The Lundbeck Foundation Nanomedicine Research Center for Cancer Stem Cell Targeting Therapeutics, NanoCAN

103


THE LUNDBECK FOUNDATION 2011 ANNUAL REPORT

LUNDBECKFOND FELLOWS Every year The Lundbeck Foundation awards fellowships to particularly promising young researchers and their research groups. The fellowships are awarded for five years and each fellowship amounts to DKK 10 million.

Name

Project title

Ass. Prof., ph.d. Henrik B. Pedersen

Exploring excited molecular matter by ultra-intense Free Electron Laser (FEL)X-ray pulses

Ass. Prof., ph.d. Anja Groth

Histone Metabolism and (Epi)Genetic Stability

Ass. Prof., ph.d. Sune Toft

Unveiling the Nature of a Newly Discovered Population of Extremely Dense, Massive, Old, “Dead” Galaxies in the Early Universe

Professor, ph.d. Jakob Balslev Sørensen

The molecular machinery for fast calcium-triggered exocytosis of synaptic and secretory vesicles

Ass. Prof., ph.d. Jakob Nilsson

Controlling the Spindle Assembly Checkpoint

Professor, ph.d. Martin Røssel Larsen

Functional characterization of Depolarisation – dependent signalling pathways in nerve terminals

Ass. Prof., ph.d. Lene Niemann Nejsum

Molecular Mechanisms Regulating Epithelial Plasma Membrane Transporter Abundance in Normal and Disease States

Ass. Prof., ph.d. Steen Brøndsted Nielsen

Exited State Physics of Bare and Solvated Molecular Ions

Ass. Prof., ph.d. Troels C. Petersen

Searching for Dark Matter at CERN’s LHC Accelerator

Post doc, ph.d. Søren G. F. Rasmussen

Structural and functional Studies of Monoamine Neurotransmitter G Protein Coupled Receptors and Monoamine Transporters

Ass. Prof., ph.d. Blagoy Blagoev

In-depth Investigation of the Processes Underlying Human Embryonic Stem Cells Maintenance and Differentiation by Advanced Quantitative Proteomics

Professor, BA, dr.phil. Marcus Thomas Pius Gilbert

Pathogen Paleogenomics – Looking Through a Window into the Genetic History of Pathogens to Better our Understanding of Their Origin, Evolution, Spread and Control

Ass. Prof., ph.d. Jes Kristian Jørgensen

The Earliest Phases of Circumstellar Disks

Ass. Prof., ph.d. Christian Adam Olsen

Gene Regulation with Small Molecule Epigenetic Modulators

Ass. Prof., ph.d. Michael Pittelkow

Dynamic Combinatorial Chemistry – Supramolecular Chemistry in Water

Ass. Prof., ph.d. Jan Arlt

Magnetism in Spinor Quantum Gases

Ass. Prof., ph.d. Niels Emil Jannik Bjerrum-Bohr

Amplitude Computation Group (CAMP)

Ass. Prof., ph.d. Mariola Monika Golas

Molecular Characterization of Cellular Assemblies Involved in Neuronal Development and Neurodegeneration

Post doc, ph.d. Himanshu Khandelia

Investigation of the Molecular Basis of Neurological Diseases Related to Ion Pumps Using Molecular Simulations

Guest Prof., ph.d. Rune Linding

Multivariate Dynamics of the JNK Phosphorylation Network and its Implications for Complex Regulatory Diseases

Ass. Prof., ph.d. Albin Sandelin

Experimental and Computational Genomics for Neuroscience and Disease Characterization

Ass. Prof., Fil. dr. Martin Snoager Sloth

Universe Origins: Probing Fundamental Physics with Planck

104


BOARD OF TRUSTEES

Mikael Rørth Chairman, Professor, Chief Physician, M.D., Copenhagen University Hospital Chairman of the Research Committee, the Biomedical Science Committee and the Investment Committee

Jes Østergaard Director, Civil Engineer Chairman of the Natural Science Committee and member of the Research and Investment Committees

Jørgen Huno Rasmussen Vice-chairman, Chief Executive Officer, FLSmidth, Civil Engineer Member of the Investment Committee

Kim Klitgaard Operator, elected by the employees of H. Lundbeck

Thorleif Krarup Director, B.Sc. (Econ.), B. Com. Member of the Investment Committee

Ken Liljegren Senior Project Manager, Civil Engineer, elected by the employees of H. Lundbeck

Povl Krogsgaard-Larsen Professor, Pharm.D. Member of the Investment Committee, the Research Committee and the Biomedical and Natural Science Committees

Peter Adler Würtzen Team Leader, Ph.D., elected by the employees of ALK

Gunhild Waldemar Professor, Chief Physician, M.D., Copenhagen University Hospital Member of the Research Committee and the Biomedical Science Committee

Management

Christian Dyvig

Chief Executive Officer

Kasper Kitaj Pedersen Britt Wilder Nina Kamille Holmgaard

Investment Director Executive Secretary Adm. Service Coordinator

Research Invest Accounting

Anne-Marie Engel Sissel Vorstrup Nina Espegård Hassel Ulla Jakobsen Kirsten Ljungdahl Heidi Stoklund Larsen

Director of Research Associate Director of Research Strategic Advisor Science Manager Secretary Student Assistant

Bertil From Jakob Munk Nielsen Christoffer Gundelach

Chief Financial Officer Senior Investment Manager Student Assistant

Claus Køhler Carlsson Vibeke P. Bache Susanne Bernth Susanne Klint Nygaard

Director, Accounting & Tax Head of Accounts Senior Controller Controller

Ventures

Mette Kirstine Agger Johan Kördel Mikael Strindlund Casper Breum Nicolai Ekström Falkenham

Managing Partner Senior Partner Senior Partner Partner Student Assistant

Emerge

Christian Elling

Partner

Design: Klaus Wilhardt Photo: Pernille Ringsing ISSN 1901-5933


The Lundbeck Foundation is an active industrial foundation that strives to maintain and expand H. Lundbeck and provide grants by:

• being an active value-adding owner of its subsidiaries and other innovative companies that are among the leaders in their respective areas of business • supporting and strengthening research in biomedicine and natural sciences of the highest international quality with ties to Denmark in order to make a significant difference to human health and life

The Lundbeck Foundation Group 2011 Revenue

€ 3.2 billion

Operating profit before tax and special items

€ 560 million

The Foundation’s share of profit for the year before grants and special items

€ 244 million

Grants

€ 68 million

Number of employees

24,676

Net wealth

€ 3.9 billion

The Lundbeck Foundation ı Vestagervej 17 ı DK-2900 Hellerup ı Tel +45 39 12 80 00 www.lundbeckfonden.com


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