CLINICAL REPORT
CLINICAL MANAGEMENT OF EXOCRINE PANCREATIC INSUFFICIENCY IN A GERMAN SHEPHERD DOG V. Dhanesh 1, Usha Narayana pillai 2 ,S.Yogeshpriya 3, 4 5 Roshna Rasheed Kutty and S.Ajith Kumar Department of Clinical Veterinary Medicine, College of Veterinary and Animal Sciences , Mannuthy INTRODUCTION: Exocrine pancreatic insufficiency is the inability to digest food properly due to the lack of digestive enzyme made by the pancreas. animal will show clinical sign if there is greater than 85 percent loss of the pancreatic acinar which has ability to secrete digestive enzyme and it is clinically characterized by loss of weight , pica, coprophagia, poor quality hair coat etc. Consistency of the faces becomes oily, smooth, and soft. Perineal region will be oily stained because of steatorrhea.
J. Ind. Vet. Assoc., Kerala. 10 (1)
CASE HISTOY AND CLINICAL INVESTIGATION A three year old GSD was presented in the university hospital Mannuthy with a history of foul smelling diarrhea of three month duration. The animal was treated with anthelmintics and Sulfa TMP combination (Septran) by local veterinarian. Owner reported that there is considerable weight loss even though the animal was take normal quantity of food. On examination, physiological parameters like temperature((103 0 F) , heart rate (108 beats / min), pulse rate (107/min) and mucous membrane (pale roseate) were found to be normal consistency of the fecal sample was found to be oily and semisolid standard parasitological examination was done and no ova of parasitic important could be detected. But large number fat globules were present in the sample. No change could be detected in Haemogram. Fecal sample was positive for X- ray film test. Based on X1. 3, 4- P.G Scholar, 2. Associate Professor , 5.Professor and Head
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ray film test and history the case was clinically diagnosed as exocrine pancreatic insufficiency.
TREATMENT AND DISCUSSION Treatment was carried out with Tab. Enzar forte, 1 tab twice daily along with this Tab. Flagyl 400 mg, 1 tab twice daily and Tab. Rantac 150 mg, ½ tab twice daily. Advised the owner to review the case after 10 days. Owner reported that animal is showing much improvement in the condition. Consistency of the feces becomes normal without any foul smell. In dog Exocrine pancreatic insufficiency is mainly due to pancreatic acinar atrophy and in cat it is due to destruction of the acinar tissue associated with subclinical or chronic pancreatitis. (Nelson et. al 2003). Pancreatic enzyme had a antibacterial property and in Exocrine pancreatic insufficiency lead to over growth of different type of bacteria in small intestine. Over growth of the bacteria will lead to changes in the small intestine like villous atrophy, alteration in the mucosal enzymatic activity etc. Bacterial count in the small intestine will be more