Microbioz India January 2018 by Microbioz India,Laboratory Equipment,Magazines,Pharma and Healthcare News,Laboratory News

26 Cover Story

Product Launches

In this issue, we have brought a cover story titled “Tips to keep your Laboratory Clean “which focuses on the importance of Cleaning equipments, lab glasswares, etc for eliminating the risk of contaminants that might affect the manufacturing process.

A product launch titled ‘Self Adhesive Profiles’by Amipolymer Pvt Ltd and grab other laboratory product updates of this month.

Market Research

We have compiled a list of Upcoming Largest Laboratory, Medical & Pharma Events and Trade Shows

Grab interesting business news collected from the world of Laboratory and Technology.

Featured article

Upcoming Events

This is not all, do not forget to read a featured article by Ami Polymer Pvt Ltd titled “Antistatic Silicones: Playing Vital Role in Food and Pharma Industries.’

ear friends, a heartiest welcome to you all in this magnificent Year 2018. I could not thank you enough for the love and endless support you shower on Microbioz India. It is only because of your blessings and the encouragement that we were able to achieve milestone victoriesby not just becoming a leading name nationally but also on an international front by associating & collaborating with more than fifteen international exhibitions in just a short span of time. We hope to get the same support in this year too so as to give you all the best you expect from us. We all understand the importance of cleanliness at our homes and the workplaces. The same is required in practically every industry where small particles interfere with the manufacturing process. So, in this issue, we have brought a cover story titled “Tips to keep your Laboratory Clean” which focuses on the importance of Cleaning equipments, lab glasswares, etc for eliminating the risk of contaminants that might affect the manufacturing process. The article also emphasizes on certain key measures that must be employed to ensure the safety during the manufacturing process and to have sustained repeatability of a quality product. This issue also brings to you the Exhibition Highlights focusing on some of the upcoming leading exhibitions of Laboratory & Scientific Equipments particularly Asia Labex Chennai & India Lab Expo, Mumbaiwhich are both going to be held in April 2018. This is not all, do not forget to read a featured article by Ami Polymer Pvt Ltd titled “Antistatic Silicones: Playing Vital Role in Food and Pharma Industries”and a product launch titled “Self Adhesive Profiles”. Also read other business news to stay updated with current market trends. I hope you have a good read. The magazine is incomplete without the love and support of the valuable readers. Your valuable feedback and suggestions are always welcome as they help us come with better content each time. For any further value addition, kindly write to us at editor@microbiozindia.com.

Cover Story

Tips to make your laboratory Clean Cleaning equipment and supplies are essential for the efficient operation of the modern research lab leaning equipment and supplies are essential for the efficient operation of the modern research lab. Other than the after-hours work done by the normal cleaning crew, cleaning is done on a regular basis by the researchers to maintain the safety of the lab environment, restore the lab after accidental spills, protect the lab equipment and instruments, and to prevent the contamination of on-going experiments from each other. Clean lab glasswares

Cleaning Always wash glass labware immediately after use. If a thorough cleaning is not immediately possible, always allow the glassware to soak. If not cleaned immediately some residues may be impossible to remove. Most new glass is slightly alkaline and should be washed upon receipt and generally can be soaked in a 1% HCL or HNO3 solution before wash and DI rinse. Never soak for long periods in strong alkaline solutions as it will damage the glass.

Always follow up a soap or acid wash with a good DI water rinse. Always use soft brushes with a wooden or soft plastic handle to avoid abrasion. Do not use wire brushes or brushes with a wire core as it can abrade the glass.

Glass cleaners Alconox is the best as itâ&#x20AC;&#x2122;s not abrasive. In fact they have a full line of detergents for soaking, hand washing and automatic washers. A detergent such as non-abrasive dishwasher soap will also work well. Always use soft brushes. Always rinse glass well and do a final DI rinse. If you need to do an acid wash, always rinse the soap off the glass completely or it may cause a reaction and leave a film on the glass. There are many lab detergents available commercially such as; Mallinckrodtâ&#x20AC;&#x2122;s KleanAR and Chem-Solv. Texwipe and EM Science also make good cleaning detergents

Clean Lab Coat and Masks

We carry many cleanroom lab coat and frock styles in different materials for your controlled environment. These lint-free lab coats are the perfect option when you want to cover most of your clothing. Our clean room lab coats and frocks vary in length from the waist to below the knee. Choose from a variety of clean processed, sterile and lint free lab coats from top manufacturers. For aseptic cleanrooms, we offer sterilized lint-free clean room lab coats and frocks. A cleanroom lab coat is generally worn in industrial clean rooms or laboratories where a coverall is not necessary. Class 1,000 ISO6+ cleanrooms generally require only a lab coat be worn. When working in a Class 10-100 clean room facility you would be required to wear a coverall to maintain the cleanliness of the room. Coveralls cover much more of your body and clothing since they have attached legs and sometimes hood and boot as well. Choosing the right cleanroom clothing and then figuring out how to put it on and take it off can be confusing. The main focus of a clean room is to eliminate any outside particles and contamination. One of the main ways

Cover Story this is done is by wearing non-shedding, clean, disposable apparel over your street clothes. Depending on the cleanliness level of your clean room, you may have to wear a full bunny suit coverall with attached hood and shoe

Alconox is the best as it’s not abrasive. In fact they have a full line of detergents for soaking, hand washing and automatic washers. A detergent such as nonabrasive dishwasher soap will also work well. Always use soft brushes. Always rinse glass well and do a final DI rinse.

like Lab Safety Supply, Inc., that contain universal or general-purpose sorbents for acids, bases, solvents, coolants, lubricants, and water-based chemicals.

Good housekeeping in the laboratory Good housekeeping practices can significantly reduce the risk of accidents and exposure to hazardous materials. Spills and accidents are more likely to occur in cluttered work spaces. Follow the good laboratory housekeeping tips below.

General tips 

covers or as little as a lab coat, bouffant cap and some shoe covers. The most common supplies used for clean-up are paper towels, gloves, and detergents and soaps (about 80% of the survey respondents indicated using these materials). Depending upon the type of ongoing research in the lab, appropriate clean-up supplies should be readily available and regular training provided to maintain the integrity and safety of the lab environment and personnel. Commercially available spill control stations are available from suppliers,



Organize bench tops with large equipment in the back and progressively smaller equipment toward the front. Leave sufficient space to perform your work safely and to avoid reaching over items that can easily get knocked over, such as graduated cylinders or flasks (Figure 2). Keep all containers and glassware at least 2 inches away from the front of the lab bench. Put away any clean glassware that is not being used. Avoid accumulating large amounts of dirty dishes on lab benches and in sinks.Clean them when your experiment is done. Never leave glassware in the sink because it can easily break. Regularly check glassware for star cracks, chips, or cracks, and

 



promptly discard or repair any unsafe glassware. Discard disposable pipettes and pipette tips immediately after use. Properly secure and label all containers of chemicals/experimental intermediates. Keep drawers and cabinets closed when not in use. Promptly clean up spilled chemicals, silica gel, and any other powdered materials to eliminate respiratory hazards Remove any equipment or clutter that interferes with access to emergency equipment such as eyewash stations, safety showers, and fire extinguishers.

Note: The information is collected for better laboratory practices from below sources. For any clarification, feel free to write: editor@microbiozindia.com

References 



https://www.drs.illinois.edu/Safet yLibrary/LaboratoryHousekeepin g https://www.laboratoryequipment .com/article/2010/11/keepinglab-clean http://www.cleanroomconnection .com/cleanroom-apparelguidelines/ http://www.cleanroomconnection .com/cleanroom-apparel/cleanroom-lab-coat/ https://www.aceglass.com/dpro/ kb_article.php?ref=8386-IPSF3037

Featured Article

Antistatic Silicones: Playing Vital Role in Food and Pharma Industries ow a days, Food and Pharmaceutical industries are facing many issues regarding safe processing operations. Major processing steps involved in drug manufacturing and delivery system are of having dynamic mechanical movements. Dynamic movement of machines generate static electricity charge on the surface of components.

Silicone is most widely used polymer in pharma industries for fluid delivery and sealing application. Naturally, Silicone rubber is having insulating properties in nature. Developed static electric charges on polymer surface can be reason of fire while contact with flammable processing solvents. Many fire incidents happened in last few years because of this reason.

103 To 105

105To 109

109To 1011

Before understanding antistatic silicone in detail, it is required to know basic about terminologies related to conductivity. Material can be categorized as per its conductivity of electric charge.

> 1012

Conductive Dissipative Anti-Static Insulative

Increasing Conductivity

Decreasing

Featured Article Silicones and other polymers fall under Insulative category. There are certain additives available in market which imparts conductivity in silicones. Extent of conductivity depends upon concentration of additives in silicone matrix. Though, it is a very challenging job to develop as these additives may affect the chemical properties of

silicone. Like food grade and Pharma grade properties may alter. Let’s understand the case through below example: Consider a fluid DCM is flowing though silicone tubing with peristaltic pump RPM of 300. Over a period of

time, static electric charge gets developed on inner surface of tubing. Boiling point of DCM is 40°C and it is flammable in nature which can generate fire on exposure of static electricity charge.

TYPES OF FOOD AND PHARMA GRADE APPLICATIONS

 



 

Silicone Tubing for Solvent Transfer from peristaltic pump Continuous motion of fluid generates static electricity charge on surface silicone tubing. Flammable fluid may catch fire due to developed electric charge.

Silicone bellow is used in pharma industries for power transfer. Vibratory action results electric charge development on surfaces which is dissipated by antistatic properties of silicone rubber



Silicone/Rubber hoses are used in pharma industries as a part of drug delivery system. High floe rate of fluid may generate static electric charge on inner liner. Antistatic silicone liner prevents charge development on liner surface.

 

Silicone Sifter sieves as used to filter the tablet fine powder for effective particle size distribution. Static electricity charge developed by Vibratory action of machine is compensated by electrically static dissipative silicone molding.

Featured Article It is matter of challenging job to produce antistatic and static dissipative silicone with achieving below compliances:   

FDA 21 CFR 177.2600- Food grade test USP CLASS VI- Biological reactivity test ISO 10993 – Biocompatibility test

Polymer industries are developing colored antistatic and static dissipative silicones. Generally black colored Polymer products are rarely in demand for pharma industry. It is all about art of compounding to achieve electrical properties with variety of colors possible like green, blue, yellow, grey etc.

It is expected that within coming years, antistatic silicone products will replace the market of general silicone products for dynamic applications. By: Vinay Pandey (B- Tech Rubber Technologist) Ami Polymer Pvt. Ltd. Mob: +91 8691013936 Email ID: tech@amipolymer.com

Event Updates

Asia labex 2018 Chennai India India’s Premier Exhibition for laboratory professionals

ASIA LABEX 2018 is an International exhibition and conference on Laboratory, Analytical, Biotech & Diagnostic Instruments & Consumables to be held on 19th -21st April, 2018at Chennai Trade Centre (CTC), Chennai,Tamil Nadu, India. The show has already generated keen interest among Industry professionals, Researchers, Laboratory and R&D heads.

instruments, Educational Lab Products for all. It will offer the exhibiting companies to not only present their innovations, products and services but to meet with the key decision makers and find the leads and confirmed orders. Attendees will have a unique opportunity to not only have the entire spectrum of the laboratory industry in one place, at one time, providing them total solution but an ideal platform to learn industry insights, connect with peers and grow It’ll be all about laboratory when Asia professionally. Labex will be hosted at CTC, CHENNAI. The focus of show is on the latest trends and technology in the Why Chennai- Tamil Nadu area of Analytical Instruments, Chromatography, Spectroscopy & Chennai is among the most visited Microscopy, Indian cities by foreign tourists,it is one Microbiology,Biotechnology & Life of the biggest cultural, economic and sciences, Laboratory Chemicals, Fine educational centres in South India.It is Chemicals &Reagent, Lab Consumables, also known by “The Detroit of India" Laboratory Glassware & Plastic With a dynamic leadership, the nation is ware,Laboratory Balances, Molecular steering to new dimensions in the field Diagnostic,Clinical of Biotechnology, Research, Diagnostic,Hematology,Hemostsis Environment and Pharmaceuticals and Diagnostic Reagents & more to emerge as a land of immense Equipment's,Laboratory Analyzers, professional opportunities. Seroloogy, Rapid Test Kits, Laboratory Automation, Environmental Lab Instruments, Nanotechnology, Laboratory Furniture, Material Testing & Measuring Instruments, Water Treatment & Filtration, Process

Industry Highlight 

The First Pharma SEZ approved by Govt. Of India is in Tamil Nadu.



10 US FDA approved, 10 UKMHRA approved and over 300 WHO GMP approved manufacturing units in Tamil Nadu.



Thrust areas of Tamil Nadu’s biotechnology industry includes healthcare, agriculture biotechnology, industrial enzymes bioinformatics, contract-research, marine and environmental biotechnology.

Asia Labex is a three day focused trade event giving the opportunity to laboratory manufacturers and laboratory suppliers to meet and do business with end users and decision makers from India’s leading industries, Research laboratories and education sector. There are 250+ exhibitors from 15 countries, 3000 brands and 8 seminar topics in the expo and seminar.

Event Updates PharmaLaboticaA dedicated conference that comprises of Panel Discussion, Product Launch, Technology Transfer and Networking session to ensure professionals in a têteà-tête. With the Industry Leading Analytical & Research Directors and Head present at Conference- it becomes very important to attend conference & its technical seminar.

Fenza Exhibition will always be striving to innovate new ways to serve our clients to learn, meet and grow. The team at Fenza Exhibitions has carved a name for themselves over the years & are well recognised in the industry for their services.

again we will create a better platform for Scientific & Laboratory Fraternity. We take great joy in providing support to our participants and we are proud to tell you that you can count on the folks behind Asia Labex to stay true to their work ethics and consistency in delivering values.

Team Fenza Exhibition would like to say thanks to all the old & new clients who For updates & any other information had put their faith and support to ASIA kindly visit: www.asialabex.com LABEX. So, we are pretty sure that once

Analytica Anacon India & India Lab Expo takes a round: It’s time for Mumbai nalytica Anacon India & India Lab Expo; leading exhibition for laboratory and analytical instruments in India, takes a round and is going to be organized at Mumbai in April 2018 along with the Hyderabad edition in September 2018. For about a decade now, the exhibition has been bringing together professionals from laboratory, analysis, biotechnology and quality control instrument manufacturers thereby putting a grand display of the latest development in the industry.

Considering an extensive presence of pharmaceuticals and laboratories in Mumbai and western share of India;

Mumbai endorses as an imperative marketplace to progress on the necessities of analytical and laboratory

Exhibition Center, in Hyderabad to capture the growth potential of the respective markets.

instruments; alongside catering to numerous buyers and end users from pharma, research, food, chemical and other vital visitor community.

Key highlights of the Mumbai edition

Mumbai, by and large, is measured to be a subsequent gigantic market after Hyderabad for laboratory and analytical instruments where an exposition of such nature categorically supports the industry and an exceptional stage for interacting within the trade. The upcoming editions of analytica Anacon India & India Lab Expo will take place on 25-26 April 2018 at Bombay Exhibition Centre in Mumbai and 6-8 September 2018 at Hitex



Highly penetrated Mumbai market attracting huge investments and industrial opportunities in pharma, laboratory and R&D Connecting with the key decision makers and leading buyers from food, pharma and chemical fraternity. Latest technological sessions, buyer seller program and extensive conference.

For details and other information:http://www.indialabexp o.com/

Market Research

Biocon teams up with Sandoz for next-gen Biosimilars BioconBSE 5.61 % and Sandoz, the generic drug division of NovartisBSE 0.15 %, have formed a partnership to develop, manufacture and sell affordable copies of biologic drugs in immunology and oncology globally.

explore opportunities together for other product.

Torrent Pharma said it plans further investments to expand the BPI

Story credit/Source: The Economic Times

Torrent Pharma buys US firm BioPharm

facilities, including its research and development (R&D) capabilities, and increase the number of product filings from BPI.

Torrent PharmaceuticalsBSE -0.34 % has acquired Bio-Pharm, a generic and

Story source/Credit: The Economic Times

Switching off enzymes to block cell division in cancer Researchers from Sweden and the U.K. have devised a new method to curb cancer growth by shutting down a single enzyme and stopping cells from dividing.

The companies will jointly develop and make the drugs known as biosimilars and obtain regulatory approvals for them globally, apart from sharing costs and earnings, Biocon said in a statement on Thursday. Biosimilars are identical copies of highly complexbiologic drugs that are said to have the same efficacy. Biologic drugs are made through biotechnology, derived from natural sources or produced synthetically. The companies will split up global sales, with North America and the European Union going to Sandoz and Biocon looking after the rest of the world. "I think both Sandoz and Biocon have good shared values and synergetic capabilities," Kiran Mazumdar-Shaw, MD of Biocon, told ET. She said Biocon will continue its partnership with Mylan and they will

Overthe-counter drugmaker based in Levittown, Pennsylvania, for an undisclosed sum. "This acquisition is an important step for increasing Torrent's presence in the United States, is consistent with our strategy of dosage form diversification, and provides us with new capabilities including manufacturing and R&D presence in the USA," the Ahmedabad-based company said on Thursday. Bio-Pharm, Inc. (BPI), which has a 75,000 sqft manufacturing facility, boasts of 10 abbreviated new drug applications (ANDAs) already approved by the US Food and Drug Administration (FDA). It has another 10 ANDAs â&#x20AC;&#x201D; or applications for approval of a generic drug product â&#x20AC;&#x201D; under review at FDA while its partners have an additional 17 products under development.

While switching off certain enzymes is an attractive approach to treat cancer, it can be difficult to create a drug that targets just one enzyme out of the thousands in the human body, the researchers from Uppsala University, Karolinska Institutet, and the University of Oxford said in a statement. The team zeroed in on the enzyme dihydroorotate dehydrogenase (DHODH), a membrane protein and a new cancer target. They used a method called nondenaturing mass spectrometry, alongside molecular dynamics simulations, to study how lipids and inhibitors bind to DHODH.

Market Research "To our surprise, we saw that one drug seemed to bind better to the enzyme when lipid-like molecules were present," said assistant professor Michael Landreh of Karolinska Institutet. DHODH also binds a lipid in the cell’s mitochondrial respiratory chain complex, suggesting the enzyme might use special lipids to locate the correct binding site on the cell membrane, Landreh said.

The gene-editing method CRISPR may also prove useful in keeping cancer growth in check. A University of Rochester team used CRISPR to remove Tudor-SN, a protein that plays a role in a preparatory phase of cell division. Cells without the protein took much longer to prepare for division, suggesting that the approach could be

GlaxoSmithKline already partners with Vectura on respiratory therapies, but some say the British pharma giant could be looking to take the pair’s relationship one step further.

Glaxo is preparing a 175-pence-pershare bid for the Chippenham, U.K.based company, sources told The Telegraph. That offer would value Vectura at close to £1.2 billion. If GSK does strike, it’ll be taking advantage of Vectura’s 2017 share price drop. In May, the FDA turned down a generic of GlaxoSmithKline blockbuster Advair from Vectura and partner Hikma, and investors have continued to pressure the stock as they await a final verdict from the regulatory

"Our simulations show that the enzyme uses a few lipids as anchors in the membrane,” said Erik Marklund of Uppsala University. “When binding to these lipids, a small part of the enzyme folds into an adapter that allows the enzyme to lift its natural substrate out of the membrane. It seems that the drug, since it binds in the same place, takes advantage of the same mechanism.” Attacking cell division to slow cancer growth is a popular idea, for the simple reason that the abnormal growth of cells is the very definition of cancer. Scientists at the Oxford Institute for Radiation Oncology and Cancer Research UK created radiation-carrying gold nanoparticles that target cell division by entering cells and shutting down telomerase. Found at the ends of chromosomes, telomerase allows cells to divide but degrades over time. In cancer, this breakdown is sabotaged, allowing the cells to multiply freely.

used to inhibit fast-growing cancer cells. The new findings from the researchers in Sweden and the U.K. were published in Cell Chemical Biology. The scientists believe their insights could lead to the development of new, more selective cancer drugs. Story source/Credit: The new findings from the researchers in Sweden and the U.K. were published in Cell Chemical Biology. Press source: Fierce Biotech

GSK eyes $1.7B bid for respiratory partner Vectura: report

agency, due this quarter, the newspaper notes. And last week’s investment strategy update didn’t sit particularly well with shareholders, either. In it, Vectura said it would increase its focus on lower-risk pipeline development opportunities and “cease” investment in “relatively higher risk, novel molecule, early stage programs,” instead looking for partnerships in that arena. While CEO Emma Walmsley has made clear that reviving Glaxo’s pharma portfolio is a top priority,, right now all eyes are on the company’s consumer unit—at least when it comes to M&A. GSK is weighing a bid for Pfizer’s onthe-block OTC division, along with rivals including Reckitt Benckiser. Story Source/Credit: By Carly Helfand Fierce Biotech

Latest Products and serum protein binding assays. The patented design consists of two chambers separated by individual membranes, eliminating the possibility of cross contamination. Available in molecular weight cut-offs of 5kDa or 10kDa, the regenerated cellulose membrane allows for sample recovery.

Designed for small volume samples, each chamber can hold 50â&#x20AC;&#x201C;250 ÂľL of sample or buffer. The standard plate footprint and well spacing meet the requirements for automation. The plate must be under 360Â° vertical rotation to achieve equilibrium. Story source: http://www.clpmag.com

Equilibrium Dialysis Plate Designed for Small Volume Samples The QuikPrep 96-well equilibrium dialysis plate from Harvard Apparatus, Holliston, Mass, is suited for highthroughput ligand-binding experiments, including protein-drug binding, proteinprotein binding, protein-DNA binding,

EKF Introduces Mobile Data Management Tool EKF Diagnostics, Cardiff, United Kingdom, has introduced POC Connect, a data management smartphone application for its DiaSpecthemoglobinanalyzer. The reagent-free hemoglobinanalyzer is lightweight and palm-sized, and delivers laboratory-quality hemoglobin results within 2 seconds at the point of care (POC). POC Connect supports mobile health checks and anemia screening in a range of locations, environments, and climates.

The new mobile app is a simple Android application that enables the storage, access, and transmission of hemoglobin results directly from the DiaSpectanalyzer to a smartphone via Bluetooth technology. DiaSpect can be purchased with integrated Bluetooth capability, eliminating the need to purchase an additional external Bluetooth dongle.

The new POC tool is designed to be useful in countries with challenging environmental and geographical conditions where remote hemoglobin

testing and access to the Internet can be difficult. The DiaSpect device records hemoglobin results with dates and times, and users can then add such unique identifiers as patient ID, user ID, quality control information, and comments. Data are synchronized and stored on the smartphone in a history list for easy access. Data can then be transferred as a protected CSV file at any time, and can be added to a central database or lab information system as required. For more information: http://www.ekfdiagnostics.com/

Latest Products consider, it is hard to find a solution that is both powerful and smart enough. SIMCA®, an established advanced data analytics and visualization program as part of the company’s proven Umetrics™ Suite, makes it possible to combine and analyze data from all sources to isolate, understand and act on the hidden gems that hold the secret to better decisionmaking and greater business success.

Canon BioMedical Launches Assays for Spinal Muscular Atrophy Canon BioMedical, Melville, NY, has introduced the Novallele copy number assay, a simplified method to investigate deletions and duplications of individual genes. Determining SMN1 and SMN2 copy number, the polymerase chain reactionbased method requires only a thermocycler capable of high-resolution melting (HRM) and a single sample replicate. The assays are bench-tested and optimized to work with multiple HRM-capable thermocyclers and numerous DNA extraction methods. With some thermocyclers, results can be generated in less than an hour. Most cases of spinal muscular atrophy are related to the deletion of a specific gene, SMN1. However, determining disease severity is a multifactor assessment relating to the copy number of a highly homologous gene, SMN2. Often, copy number variation studies of SMN1 and SMN2 require a combination of specialized instrument systems, laborious workflows, and expensive reagents.

For more information,visit: https://www.canonbiomedical.com/online/portal/vp7

Sartorius Stedim Biotech Launches New Versions of Data Analytics Software Solutions SIMCA® and SIMCA®-online software updates in the Umetrics™ Suite help manufacturing industries make better business decisions and optimize process control Sartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, has introduced a new version of its SIMCA® and SIMCA®-online data analytical solutions, which are offered by its subsidiary Sartorius Stedim Data Analytics, formerly known as Umetrics. Every day, businesses generate a vast array of data derived from a variety of different sources. This data holds the key to better performance. The challenge is to interpret this information in a meaningful way.

SIMCA®’s multivariate data analysis engine enables companies to swiftly detect and analyze deviations from normal operating conditions by modeling an idealized process. Once this model is transferred into SIMCA®online, it serves as a valuable reference for your current production. The newly enhanced software offers an intuitive graphical interface and the flexibility to handle complex data, such as reworking, splitting and merging, and more. SIMCA® projects can be uploaded directly to an available SIMCA®-online server for real-time visualization of the process from a data point of view. The real-time monitoring and prediction system, SIMCA®-online, constantly monitors processes to provide a continuous snapshot of the users’ operations. It not only helps to identify when set parameters change, but also enables remedial action to be taken before production is affected, ensuring that product quality remains consistent. With this level of control, it is possible to maximize resource efficiency, minimize operational costs and benefit from increased confidence in end-product quality. Among the new features in SIMCA®-online is the selfservice analytics capability, which allows anyone to create fundamental process models, regardless of their background. For more information:https://www.sartorius.com

However, with so many parameters and such vast system complexity to