Microbioz India, September 2018, Medical Edition

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Sleep deprived people more likely to have car crashes 21

The edition brings for you a cover story Self love and modern women: A lost art of healthy living Authored by Heena Lakhani, Assistant Professor, Psychology, Arihant College, and Indore

Product Launches

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The edition also covers recent Healthcare news articles and product launches collected from worldwide sources to update the readers with the current trends in the industry

Study reports risk of rare adverse outcomes from 19 breast implants Washington D.C. [USA], Sep 18 (ANI): According to a study, silicone breast implants could increase the risk of several rare adverse outcomes in women."We are reporting an analysis of the largest prospective study to date on silicone breast implant safety," commented Mark W. Clemens of The University of Texas M.D. Anderson Cancer Center, Houston.

Washington D.C. [USA] Sep 18 (ANI): Sleep deprived? You may have a higher risk of crashing your car. According to a new study, people who have slept for fewer than seven of the past 24 hours have higher odds of being involved in car crashes. The risk is greatest for drivers who have slept fewer than four hours.

Mologic Commences Clinical Trial of Urine-Based Diagnostic for Cystic Fibrosis

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Personalized diagnostics developer Mologic Ltd, Bedfordshire, UK, has commenced a clinical trial to evaluate its urine-based diagnostic, Headsup, for monitoring pulmonary exacerbation in patients with cystic fibrosis (CF).

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ear friends and readers, with gratitude in our heart for your extreme love and support, once again we have brought the special edition of your favorite publication “Microbioz India”.

Through our contacts and consistent pursuance, we have made the best attempt and efforts to enrich this edition with excellence articles giving you significant and insightful information about the current trends in Medical Industry.

The cover story of the edition is titled, “Self love and modern women: A lost art of healthy living” and is authored by Ms. Heena Lakhani, Assistant Professor, Arihant College, Indore who has emphasized on treating a patient beyond medicines.

She says, the wonder women today is expected to be constant and efficient all rounder, juggling between relationships, kids, family, career and herself. From being an intelligent daughter, supportive sister, supermoms and dedicated employees; every role is played well by the women of modern times.

The ever running race of being perfect in all dimensions of life have made the modern women forget the essential art of self love which is necessary for healthy living. Aiming for perfection generates a toxic by product which is lack of self love and according to WHO symptoms of depression, anxiety and unspecified psychological disorders are twice more common in woman than in man.

As always, the edition continues to bring for you the latest market research news and product launches collected from worldwide sources to keep you updated with what’s going on in the industry.

Dear friends and readers, I hope you received some good & valuable information through our magazine. Once again, I would like to thank you for your invaluable love and support.

We are always eager to receive your valuable feedback and suggestions, as it will help us to come-up with better content each time. For any further value addition, please write to us at editor@microbiozindia.com.

Cover Story

Self love and modern women A lost art of healthy living The wonder women today is expected to be constant and efficient all rounder, juggling between relationships, kids, family, career and herself. From being an intelligent daughter, supportive sister, supermoms and dedicated employees; every role is played well by the women of modern times. The ever running race of being perfect in all dimensions of life have made the modern women forget the essential art of self love which is necessary for healthy living.

Aiming for perfection generates a toxic by product which is lack of self love and according to WHO symptoms of depression, anxiety and unspecified psychological disorders are twice more common in woman than in man.

The good news is the most important things come for free and from many different paths.

To rediscover the self love baby step one at a time will be really helpful. To start with carve a “ma time” each day, which will be dedicated to something which gives you joy, do it because you love it and not for any other reason. Cultivate a positive inner advocate which speaks for you, when your mind criticizes you.

Forgive yourself for being messy and of that old failure.

Now, let’s first understand what self love is and what makes it so important. Oscar Wilde wrote,” To love oneself in the beginning of a lifelong romance.” Self

love is combination of self compassion and self kindness; one should feel to be mentally healthy and happy in life.. Self love is like a flow of fresh water when our internal monologues are mud with harsh judgments for our mistakes and judgments. Self love should not be confused with manipulative words we speak to our self to quick fix our situation, rather the practice of self love has a tendency to heal us and improve our emotional intelligence, wisdom and optimism. Self love if practiced regularly can open gates of profound wisdom of self compassion which will lead to self healing.

But, in midst of being a Beti, Bahu, Patni, and a supportive worker or a brilliant boss, the modern super woman today have long forgotten the key art of self love. And the lack of self love has made women today feel overwhelmed and stressed out.

They easily get stuck in unhealthy relationship and get critical towards their own self. Obsession to perfection, fear of wrong choices and commitments, lack of directions, eating disorders, hyper vigilance, poor communication, complex relationship, lack of assertiveness, body shaming, over sensitiveness , anxiety and anger have been served on table due to major ingredient absent from life which is self love and kindness. All these symptoms have directly and indirectly added to risk of getting many personality disorders .self love may not be an antidote for depression or anxiety, but self love does reduces chances of getting mentally sick and improve your personal health.

The good news is the most important things come for free and from many different paths. To rediscover the self love baby step one at a time will be really helpful. To start with carve a “ma time” each day, which will be dedicated to something which gives you joy, do it because you love it and not for any other reason. Cultivate a positive inner advocate which speaks for you, when your mind criticizes you. Forgive yourself for being messy and of that old failure. Be kind to yourself by taking good care of your body and soul. Get enough sleep, eat fruits and vegetables and get some form of exercise on a regular basis.

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Cover Story Woman, you are a Queen, when stressed take a break, respect yourself and treat yourself, remember the shopping therapy!!!!

Remember what Maria Robinson said, “Nobody can go back and start a new beginning, but anyone can start and make a new ending.� So dint get stuck in past, the future is still in your hands. And lastly, for a good mental health and general well being, I suggest you to keep yourself first, let people think you are selfish. All the very best..!!

Authored By: Heena Lakhani B.com (Hons.), MBA (Finance and Human Resource Management), MA in Psychology (Clinical Psychology), Assistant Professor Arihant College, Indore, Madhya Pradesh A teacher by choice and a lifelong learner, Ms. Lakhani has a rich experience of 5 years in college teaching and communication training. She has been a proud alumnus of prestigious institutes of Madhya Pradesh. Always keen to learn her, it is her passion to explore new ways to make learning easy through experimentation and observation. She enjoys learning and teaching Entrepreneurship, Business Communication, Economics and Human Resource Management. She is well loved amongst her students for a unique style of teaching that includes story telling as prominent method.

Business News

International Symposium on Robotic Joint Replacement Held in Pune Pune (Maharashtra) [India], Sep 15 (Business Wire India): More than 250 Ortho Surgeons from all over the globe attended the International Symposium on Robotic Joint Replacement organised by Lokmanya Hospitals, a pioneer of Robotic Surgery in India, at JW Marriott, SB Road recently.

Dr. Narendra Vaidya, Chairman, Lokmanya Hospitals

The two-day deliberations included expert national and international speakers and case studies, paper presentations, live surgeries and the way forward for Joint Replacement technologies. This symposium, in tune with the need of the times, was aptly based on the theme "Interactive Technology" and was adorned by experts who have witnessed the transition from conventional to Robotic Technologies.

During this conference, experts opined that with more accuracy, decreased operating time, less invasive, robotic assisted Knee Surgeries have resulted in improved patient outcomes.1500 ortho surgeons watched live surgery through webcasting across the globe.

It was a great platform for sharing knowledge and experience, new technology adoption for the benefit of arthritis patients.

Dr. Narendra Vaidya, Managing Director, in his inaugural address said that the fact that about 159 surgical robotic systems are being developed, especially North America and Europe shows the need of these technologies for the patients and the interest that experts are taking in developing these technologies.

With more accuracy, less operating time, minimally invasive technologies patient recovery is faster and therefore Robotic Knee Replacement technologies are here to stay.

The cost of these treatments is high and patients have been going to Europe and the US for treatments. But we have made quality and high-end treatments available at affordable costs here in India. Organising the first International Symposium is a concrete step in that direction by exchanging ideas and training the doctors, he added.

The topics discussed include Conventional Knee Replacement - What is lacking? Evolution of technology in arthroplasty, Robotic Surgery with surgeon's and engineer's perspective, brainstorming on various topics, case studies, a debate on conventional v/s robotics.

The problem of knee pain is a challenge world over.

Every third person In US about 91 million people suffer from joint pain, while in India about 28.7 per cent people in the age group above 60 years suffer from joint pain. Sedentary Lifestyles, lack of exercise, bad eating habits are causing joint problems in ageing population. Robotic Surgeries are precise and minimally invasive and result in faster recovery.

(Business Wire India)

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Business News

Study reports risk of rare adverse outcomes from breast implants Washington D.C. [USA], Sep 18 (ANI): According to a study, silicone breast implants could increase the risk of several rare adverse outcomes in women.

"We are reporting an analysis of the largest prospective study to date on silicone breast implant safety," commented Mark W. Clemens of The University of Texas M.D. Anderson Cancer Center, Houston.

a serious type of skin cancer, was nearly four times higher in women with silicone implants.

Compared to saline-filled implants, silicone implants were also linked to a higher risk of some surgical complications. These included capsular contracture (scarring around the implant), which occurred at a rate of 5.0 percent with silicone implants versus 2.8 percent with saline-filled implants. Capsular contracture occurred in 7.2 percent of primary breast augmentation procedures, and was the most common reason for reoperation in this group.

While certain rare harms appeared to be more common in women with silicone implants, absolute rates of these adverse outcomes were low.

The findings appear in the journal Annals of Surgery.

(ANI)

Women with undiagnosed STIs at greater risk of negative PMS symptoms

"We are sharing critical information on complication rates and rare associations with systemic harms. This data gives women important safety information about silicone breast implants to have real expectations and to help them choose what is right for them," added Clemens.

Women receiving silicone implants were at increased risk of several rare harms compared to the general population. The elevated risks included three conditions classified as autoimmune or rheumatologic disorders: Sjogren's syndrome, with a risk about eight times higher than in the general population; scleroderma, a seven-fold increase in risk; and rheumatoid arthritis, about a sixfold increase in risk.

"These findings are associations compared to the general population and determining why these associations are observed or any causation requires further study," said Dr. Clemens.

Silicone implants were also associated with a 4.5-fold increase in the risk of stillbirth, but no significant increase in the risk of miscarriage. Risk of melanoma,

Washington D.C. [USA], Sep 18 (ANI): Undiagnosed sexually transmitted infections (STI) can increase negative premenstrual symptoms (PMS) in women, according to a study.

Despite being known to have an anti-social effect on women's lives, altering their moods, energy levels, eating habits and even sex drive, periods are not recognised as a scientific factor in the study of female health.

However, since some STI infections are asymptomatic, for instance 70 percent of people diagnosed with Chlamydia are unware of it, and can lead to fertility issues, the study authors caution that

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Business News these results are significant, and that reproductive healthneeds to be taken more seriously by both the scientific community and women in general.

Lead author Dr Alexandra Alvergne of Oxford University, said: "Even now, when I write a research application on PMS, I still think 'will this be taken seriously?' that needs to change. Not understanding or even acknowledging that PMS is more than 'women's raging hormones' but rather, the byproduct of cyclical immunity makes it harder to identify diseases and can even delay diagnosis of infections such as STIs, which can affect women's fertility."

Dr Alvergne said: "Our research shows that by better understanding their period and menstrual cycle, women could potentially improve their health. If you know that severe PMS could be an indicator of an underlying STI, you are more likely to listen to your body."

The study appears in the journal Trends in Ecology and Evolution. (ANI)

Sleep deprived people more likely to have car crashes Washington D.C. [USA] Sep 18 (ANI): Sleep deprived? You may have a higher risk of crashing your car.

According to a new study, people who have slept for fewer than seven of the past 24 hours have higher odds of being involved in car crashes. The risk is greatest for drivers who have slept fewer than four hours.

quantify the relationship between how much a driver has slept and his or her risk of being responsible for a crash.

For this new study, researchers analysed data from a previous study by the U.S. Department of Transportation, which involved in-depth investigations of a sample of 5,470 crashes, including interviews with the drivers involved.

The researchers here found that drivers who reported fewer than four hours of sleep had 15.1 times the odds of responsibility for car crashes, compared with drivers who slept for the recommended seven to nine hours in the preceding 24-hour period, comparable to the U.S. Researchers involved in the study also discovered that drivers who reported six, five, and four hours of sleep in the past 24 hours had 1.3, 1.9 and 2.9 times the odds of responsibility for a crash, respectively, compared with a driver who slept for seven to nine hours.

Drivers who reported less than four hours of sleep had a particularly elevated risk of singlevehicle crashes, which are more likely to result in injury or death. Drivers who had changed their sleep or work schedule in the past week and drivers who had been driving for 3 hours or longer without a break were also found to be at increased risk.

Study author Brian Tefft said, "Being awake isn't the same as being alert. Falling asleep isn't the only risk.

Even if they manage to stay awake, sleep-deprived drivers are still at increased risk of making mistakes -like failing to notice something important, or misjudging a gap in traffic -- which can have tragic consequences."

The full findings are present in the journal- Sleep.

(ANI)

Psychotherapy benefits women caring for kids with health issues Washington D.C. [USA], Sep 17 (ANI): Turns out, brief cognitive behavioural therapy significantly improved the mental health of women overwhelmed by caring for children with severe chronic health conditions.

While the dangers of driving drowsy were already well known, this is the first peer-reviewed study to

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Business News Due to their child's care requirements, the women had difficulty getting together with friends because they couldn't hire a babysitter who knows about medical equipment or complex health conditions, so people were cut off from a lot of social support.

The findings were presented at the Council for the Advancement of Nursing Science State of the Science Congress on Nursing Research. (ANI)

Researchers at the University of Louisville found that after five therapy sessions, study participants reported significantly decreased depressive symptoms, negative thinking, and chronic stressors, and experienced improved sleep quality.

"Women caring for children with chronic conditions such as cerebral palsy and cystic fibrosis are at high risk for depressive symptoms. They have many things to juggle, including caring for the child, administering medications and coordinating physician and therapy visits. They're stressed and overwhelmed by the amount of care their children require and the number of hours a day it takes," said study author Lynne Hall.

About 15 million children in the United States have special health care needs and women constitute 72 per cent of the caregivers of those children.

The study revealed that women caring for children with serious health conditions should be screened for depression and that cognitive behavioural therapy (CBT) is an essential treatment for this population.

Brief CBT, a short-term, goal-oriented psychotherapy takes a hands-on, practical approach to problemsolving and focuses on changing patterns of thinking or behaviour to decrease negative thoughts and improve recognition of one's ability to cope.

For the study, 94 female caregivers with high levels of depressive symptoms were randomly assigned to either a control group or an intervention group, which received five 45 to 60-minute sessions of CBT. The women also were given homework that centred on examples of cognitive distortions with positive substitutions, a thoughts log, and instructions for practising relaxation.

"A lot of these women said they felt very isolated and there was no one who would listen to them," said Catherine Batscha, a psychiatric-mental health nurse practitioner who provided CBT to the study participants.

Pollen exposure during pregnancy linked to baby asthma risk Washington D.C. [USA] Sep 17(ANI): Turns out, children born in the peak grass pollen season, October and December, may have a greater risk of developing respiratory diseases such as asthma.

Led by La Trobe University, a team of local (The MACS study) and international (COPSAC2000 and LISAplus) researchers analysed cord blood collected from hundreds of babies born in Melbourne, Denmark, and Germany.

They discovered those born during the peak grass pollen season in both hemispheres had high immunoglobulin E (IgE) levels in umbilical cord blood - a marker used to predict the development of allergic diseases.

Lead researcher, Bircan Erbas from La Trobe's School of Psychology and Public Health, said the aim of the study was to determine the effect of exposure to high grass pollens during pregnancy and soon after birth.

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Business News "We know that outdoor pollen exposure during the first couple of months after birth can lead to allergic respiratory diseases and we suspected that exposure during the later stages of pregnancy may also be important," Erbas said.

Many studies have shown that babies with high levels of IgE in cord blood can go on to develop allergies later in childhood, but little is known about how these levels are affected by exposure to pollen in utero." The researchers found high IgE levels among babies born in October and December in Melbourne.

Erbas added, "We found these babies had lower IgE levels. This was a significant finding and indicates the possible development of a sensitisation barrier.

However, more research needs to be done and currently, we are working on studies to identify the specific risk time periods of pollen exposure during pregnancy on asthma and allergies in children."

She stressed that the study did not suggest that all babies born during high pollen seasons would develop a respiratory disease or other allergies.

"The study provides new insight that could help us predict and manage diseases like asthma which are a significant public health burden. However, it's important to remember there are a number of factors that can determine who gets asthma or allergies. This is one piece of the puzzle," added Erbas.

The full findings are published in the journalEnvironment International. (ANI)

Lesbian, gay, bisexual youth at increased risk of substance abuse

Washington D.C. [USA] Sep 16 (ANI): Young adults who identify as lesbian, gay or bisexual are at a higher risk of consuming substances such as alcohol, nicotine, and marijuana, as compared to their heterosexual peers.

A new study from Oregon State University found that polysubstance use is an issue among many youths who identify as sexual minorities, meaning they are facing added health risks.

Assistant professor Sarah Dermody said, " There are also differences among the subgroups of youth who identify as sexual minorities, suggesting we need to look beyond the averages to understand what factors may be influencing substance use in this population."

Sexual minority is an umbrella term for those who identify with any sexual identity other than heterosexual or who report same-sex attraction or behavior. For the purposes of the study, the researchers focused on those youth who identified as lesbian, gay or bisexual.

"The goal of the new study was to better understand the risks associated with polysubstance use, or the use of three or more types of drugs, among sexual minority youth. It is an area of research that is largely unexamined," said Dermody.

The findings suggested that it may be a good practice for health care providers who serve these youth to conduct assessments for substance use as part of regular health screenings.

Further research is needed to determine what factors may be contributing to increased substance use among youth identifying as sexual minorities, and why those factors may impact some more than others.

The study is published in the journal- Drug and Alcohol Dependence. (ANI)

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Product Launches

Single-Sample MicroOsmometer for Direct Sampling

The Osmo1 uses the industry-preferred freezing point depression method to deliver results in 90 seconds. It can be used for a variety of clinical diagnostic applications, including critical care, endocrinology, surgery, and urology/renal function testing.

Advanced Instruments, Norwood, Mass, an authority in osmometry, has released the newest member of its Advanced family of freezing point osmometers, Osmo1, for clinical laboratories that directly draw and test small sample volumes. The new instrument replaces the company’s Advanced 3320 osmometer, currently used in thousands of laboratories in the US and worldwide.

Byron Selman, MBA, Advanced Instruments.

A versatile laboratory instrument suited for any laboratory setting, the Osmo1 also features a dedicated space to hold the newly repackaged MicroSample test kit that now includes sampler tips, chamber cleaners, and replacement plunger wire conveniently packaged together.

Designed for sample-limited applications, the Osmo1 uses a 20 μL sample size and can measure the osmolality of body fluids—including feces, plasma, serum, sweat, tissue homogenate, urine, and whole blood. Samples are analyzed one at a time; the process is facilitated by the instrument’s operating cradle, which enables tests to be run directly from the Ease-Eject Sampler, eliminating any loss of sample.

The redesigned instrument features an interactive touchscreen, an onboard printer, and a 2-D barcode scanner to provide positive sample identification and reduce transcription errors. Data management and transfer can be handled via the onboard printer or by exporting data using the instrument’s Ethernet connection or multiple USB ports.

“The Osmo1 was designed with a set of usability, connectivity, and software control features consistent with the demands of today’s overworked, highly regulated laboratories,” says Byron Selman, CEO of Advanced Instruments.

“It represents Advanced Instruments’ commitment to innovation in the field of osmometry while maintaining the same product quality and reliability. We have expanded the product’s data management and communication features in response to evolving daily requirements in busy laboratories around the world.”

To learn more, visit https://www.aicompanies.com/

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Product Launches

Mologic Commences Clinical Trial of UrineBased Diagnostic for Cystic Fibrosis

Personalized diagnostics developer Mologic Ltd, Bedfordshire, UK, has commenced a clinical trial to evaluate its urine-based diagnostic, HeadsUp, for monitoring pulmonary exacerbation in patients with cystic fibrosis (CF).

The study aims to identify five urinary biomarkers associated with the onset of pulmonary exacerbation in adults with CF. It will also validate use of the novel point-of-care test, which is designed to enable patients with CF to self-monitor.

Patients will be recruited for the clinical trial from the West Midlands Adult CF Center, where they are under the care of the trial’s principal investigator, Edward Nash, MD. As one of the largest CF units in the UK, the center currently provides care for more than 350 adults with CF. The HeadsUp test is based on regularly measuring five different biomarkers in urine and using an appimbedded algorithm to the measurements to a traffic light red-yellow-green result, indicating whether the patient is stable or in need of medical intervention.

In phase 1 of the study, participants will perform a number of regular physiological tests, and will provide a daily urine sample to Mologic. Analysis of the samples will confirm which of the urinary biomarkers already identified are the key five associated with the onset of pulmonary exacerbation.

In phase 2 of the study, patients will be asked to perform the HeadsUp test daily to validate the selection of biomarkers, and to provide information about the usability of the system.

“Our aim has been to develop a simple, noninvasive test that helps patients suffering from chronic lung disease to understand, monitor, and manage their condition at home,” says Paul Davis, Mologic cofounder and chief scientific officer. “We have

identified the biomarkers in urine that reflect critical changes in the lung and are linked with the onset of an attack. Using the techniques underlying a standard pregnancy test, the CF HeadsUp device can measure a subset of these biomarkers and transform the data into straightforward actions and medications. We now look forward to clinical trials and working with the West Midlands Adult CF Center to build evidence and refine the tests through patient feedback.”

“For people who suffer from a chronic lung disease such as CF, there is an ever-present risk of recurrent lung attacks (exacerbations) during which every breath can be a struggle,” adds Nash. “HeadsUp is noninvasive and allows frequent testing in the home, empowering patients to take control of their condition, which has the potential to reduce lung damage and avoid stays in hospital.”

To learn more, visit https://mologic.co.uk/

MedTest Dx Unveils Hematology Analyzer for High-Throughput Decentralized Testing

MedTest Dx, Canton, Mich, has announced the launch of its BC-5390 automated 5-part differential hematology analyzer. According to the company, the BC-5390 analyzer provides rapid, reliable, and flexible testing from just 33 µL of blood. It achieves accurate 21-parameter, 5-part differential readouts by utilizing three proven technologies, with a throughput of 60 samples per hour.

Additionally, the BC-5390 analyzer offers closed-tube sampling, and its continuous-batch 40-tube autoloader facilitates random-access testing. The instrument’s Windows-based software makes it easy to perform routine tests, manage patient results, set up auto-cleaning, and connect with a laboratory information system.

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Product Launches

The analyzer is FDA 510(k) cleared, CE marked, and licensed by Health Canada Medical.

Wayne Brinster, MedTest Dx. “The new BC-5390 differential hematology analyzer is an ideal choice to streamline daily workflow in the hematology lab,” says MedTest Dx CEO Wayne Brinster. “It is a robust, flexible, automated system manufactured for reliability. Its easy-to-use software, lower cost, simplified reagent management, and nontoxic consumables are popular with users.”

To learn more, visit http://www.medtestdx.com/

Spectrum Preimplantation Genetic Testing for Aneuploidy Improves IVF Outcomes

Noninvasive genetic testing laboratory Natera Inc, San Carlos, Calif, has announced the publication of study results demonstrating that the company’s Spectrum preimplantation genetic screening test for aneuploidy (PGT-A) can improve in vitro fertilization (IVF) results for all women, including those of advanced maternal age.1 The study retrospectively analyzed pregnancy outcomes from more than 1,800 IVF cycles performed at two fertility centers using Spectrum, a single-nucleotide polymorphism (SNP)-based PGT-

A technology. Spectrum screens all 24 chromosomes to provide comprehensive embryo aneuploidy results. Aneuploidy, an abnormal number of chromosomes, is common in human embryos— particularly as women age—and is the primary cause of failed IVF.2 In the United States, less than half of all in vitro transferred embryos implant and lead to pregnancy.3,4 According to Natera, the recent study indicated that use of Spectrum PGT-A testing during IVF led to increased rates of implantation (70%), clinical pregnancy (71%), and live birth (65%). The rates were achieved primarily with single embryo transfer (SET), substantiating routine use of SET with SNP-based PGT-A. In addition, with the use of PGT-A, pregnancy implantation rates remained high even among older women, supporting the use of PGT-A to improve implantation rates in women of advanced maternal age.3,4

Kimberly Martin, MD, Natera.

“This study shows that Spectrum PGT-A can help mitigate the negative effects of maternal age on IVF outcomes by allowing selective transfer of embryos that are more likely to lead to sustained implantation,” says Kimberly Martin, MD, Natera’s senior global medical director for women’s health.

“These findings also demonstrate that successful IVF can be achieved without multiple-embryo transfer when combined with PGT-A. Increased use of single embryo transfer should reduce the incidence of multiple pregnancies, which are associated with higher pregnancy complication rates, in addition to financial and psychosocial challenges for families.”

Spectrum’s patented SNP-based technology provides a comprehensive 24-chromosome PGT-A with an accuracy greater than 99% per chromosome call, helping provide the best chance of transferring an embryo with the correct number of chromosomes.

Identifying the healthiest embryos for transfer improves the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum is part of Natera’s portfolio of genetic diagnostic and screening tests designed to help families on the path to parenthood.

The Spectrum preimplantation genetic test was developed by Natera under terms of the Clinical Laboratory Improvement Amendments of 1988 (CLIA). FDA does not currently clear or approve

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Product Launches Laboratory-developed tests, but CLIA certification of the laboratory is required to ensure the quality and validity of such tests.

For more information: https://www.natera.com/ References 1.

2.

3.

4.

Simon AL, Kiehl M, Fischer E, et al. Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24chromosome single-nucleotide polymorphismbased preimplantation genetic testing for aneuploidy.Fertil Steril. 2018;110(1):113–121; doi: 10.1016/j.fertnstert.2018.03.026.

Hodes-Wertz B, Grifo J, Ghadir S, et al.

Idiopathic recurrent miscarriage is caused mostly by aneuploid embryos.

Fertil Steril.

2012;98(3):675–680; doi: 10.1016/j.fertnstert.2012.05.1025.

2015 Assisted Reproductive Technology National Summary Report. Atlanta: Centers for Disease Control and Prevention, American Society for Reproductive Medicine, Society for Assisted Reproductive Technology, 2017.

Available at: www.cdc.gov/art/pdf/2015report/art-2015-national-summary-report.pdf.

Accessed September 16, 2018.

Toner JP, Coddington CC, Doody K, et al.

Society for Assisted Reproductive Technology and assisted reproductive technology in the United States: a 2016 update. Fertil Steril.

2016;106(3):541–546; doi: 10.1016/j.fertnstert.2016.05.026.

New Microtip Partnership Assays for Diabetes, Cardiac, and Renal Testing Published on September 8, 2018

Global in vitro diagnostics manufacturer Ortho Clinical Diagnostics, Raritan, NJ, in collaboration with Diazyme Laboratories Inc, Poway, Calif, now offers three new Microtip Partnership assays to their customers. With the new assays for cystatin c, glycated serum protein (GSP), and lipoprotein (a) (Lp (a)), Ortho enhances its offerings for diabetes monitoring as well as cardiac and renal testing. The

Microtip Partnership program enables Ortho to validate and offer high-value esoteric testing, in step with evolving laboratory needs.

“Our Microtip Partnership assay program helps us expand our reach in delivering innovative, important new assays to our customers,” says Robert Yates, COO of Ortho. “Ortho is a leader in testing in diabetes, cardiac, and renal areas, and the three new assays we announce today further that position and commitment.”

Robert Yates, Ortho Clinical Diagnostics.

Cystatin c is a key marker for early diagnosis of chronic kidney disease, and complements serum creatinine testing. Combining cystatin c with serum creatinine can improve the predictive accuracy for allcause mortality and end-stage renal disease, as it is a more sensitive marker in the creatinine blind range in kidney testing.

The GSP assay enriches the company’s diabetes menu, adding to recent launches of Microtip Partnership assays for beta-hydroxybutyrate, cpeptide, and insulin. Glycemic monitoring is critical in the prevention or delay of diabetesrelated complications and comorbidities.

The Lp (a) assay expands Ortho’s offering of diagnostic cardiac markers for patients who may have a genetic risk factor for premature cardiovascular disease, including risk stratification for myocardial infarction and stroke.

The assays will initially launch in Africa, Europe, the Middle East, and the United States.

To learn more, visit https://www.orthoclinicaldiagnostics.com/home

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Product Launches

All-in-One Eye Wash Provides Immediate First Aid for the Eye

Contact with acids and corrosive substances can damage eyes after only 10 seconds of exposure.

Having instant access to fast, safe, and effective first aid can help minimize the likelihood of permanent damage and relieve irritation and discomfort from these and other foreign particles, such as dust and debris that may enter the eye.

Aero emergency eye wash solution, distributed by Bel-Art–SP Scienceware, Wayne, NJ, is an all-in-one eye wash that combines sterile saline with a buffered, pH-neutralizing solution to rinse impurities and irritants from the eyes, and to help the eye return to a

normal pH level of 7.4 by quickly neutralizing corrosive chemicals.

“The 16-oz. and 32-oz. bottles have a unique eye-opener that allows used fluids and contaminants to flow away from the eye,” says Peter Yoo, portfolio manager at Bel-Art– SP Scienceware. “This is important, as you don’t want the contaminated fluid to reenter the eye.”

Along with the 16-oz. and 32-oz. sizes (32-oz. size available in November 2018), the company also offers 5-oz. and ½-oz. sizes that can easily be included in a portable workstation or carried in a pocket. All of the bottles have easy-to-open, quicktwist tops for immediate access. A wall-mounting station that contains two 16-oz. bottles is also available. It includes a cover to shield the bottles from dust and impurities, and a handle for easy transport.

Aero emergency eye wash solution has an expiration date of 4 years from the date of manufacture. The solution meets FDA requirements for eye wash (21 CFR 349), and also meets ANSI Z358.1-2009 requirements for a personal eye wash. It is suited for the laboratory, classroom, worksite, and public facilities, according to the company.

For more information, visit https://www.belart.com/

RNI NUMBER: UPENG/2017/73675