Laboratory Information Management System

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The cover story titled ‘Laboratory on the fingertips: Laboratory Information Management System is authored by Scolastica Becky Bello, Editorial team, Microbioz India magazine.

Research Updates

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We have covered major research news from a number of areas like Biotechnology, Microbiology and Health Sciences to keep you updated with latest breakthroughs and discoveries around the globe.

Product Launch

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We have covered major research news from a number of areas like Biotechnology, Microbiology and Health Sciences to keep you updated with latest breakthroughs and discoveries around the globe.

Medicall

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‘Medicall- Hospital Needs Expo’ is organized by Medexpert Business Consultants Pvt. Ltd.

Scientists report new limits to functional DNA elements of human genome 24 According to the new calculations by an evolutionary biologist, it has been reported that no more than 25 percent of the human genome is functional.

Upcoming Shows/Events/Exhibitions

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We have compiled a list of Upcoming Largest Laboratory, Medical & Pharma Events and Trade Shows

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t is the month of July and this reminds us of one of the India’s largest medical equipment exhibition for Medical professionals named ‘Medicall’ going to be held in Chennai this month. So, with immense pleasure here I am releasing our First Event Special Issue for 2017 – A Medicall Special Issue which do not only mark the presence of Microbioz India in Medicall but also many other National and International events that have been lined up for this year. The list of the events with the brief can be found in the magazine. ‘Medicall- Hospital Needs Expo’ is organized by Medexpert Business Consultants Pvt. Ltd. Promoted by Dr. Manivannan, the Joint Managing Director of Kauvery Hospital, a 1000 bedded Hospital in South India. This hospital was started 11 years back with 30 beds by young professionals with limited knowledge about hospital industry. They faced many hurdles in the course of their growth. Medicall was born with the idea to share their expertise with the fellow medical fraternity. The cover story for this issue is titled Laboratory Information Management System and authored by one of the stunning author and editor of Microbioz India Rebecca Bello. A Laboratory Information Management System (LIMS) is software that allows you to effectively manage samples and associated data to improve lab efficiency. By using a LIMS, your lab can automate workflows, integrate instruments, and manage samples and associated information. The cover story discusses how labs that use LIMS boost their level of professionalism and their ability to meet customer demand. As always, we have also kept some major research news from a number of areas like Biotechnology, Medical Technology and Health Sciences in the research updates section to keep you updated with latest breakthroughs and discoveries around the globe. The magazine also contains a new series called ‘Product Launch’ where you can find any new technologies/products that are being developed for your immediate awareness and knowledge. Dear friends and readers, once again I would like to thank you for your invaluable love and support. As always, we hope that you find value in this issue. We are always eager to receive your valuable feedback and suggestions as they help us come with better content each time. For any further value addition, please write to us at editor@microbiozindia.com.

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Cover Story

aboratories around the world depend on a LIMS to manage data, assign rights, manage inventory, and more. A laboratory information management system (LIMS), sometimes referred to as a laboratory information system (LIS) or laboratory management system (LMS), is a software-based laboratory and information management system with features that support a modern laboratory's operations. Key features include but are not limited to workflow and data tracking support, flexible architecture, and data exchange interfaces, which fully "support its use in regulated environments". The features and uses of a LIMS have evolved over the years from simple sample tracking to an enterprise resource planning tool that manages multiple aspects of laboratory informatics.

Historically the LIMS, LIS, and process development execution system (PDES) have all performed similar functions. The term "LIMS" has tended to refer to informatics systems targeted for environmental, research, or commercial analysis such as pharmaceutical or petrochemical work. "LIS" has tended to refer to laboratory informatics systems in the forensics and clinical markets, which often required special case management tools. "PDES" has generally applied to a wider scope, including, for example, virtual manufacturing techniques, while not necessarily integrating with laboratory equipment.



Cover Story

In recent times LIMS functionality has spread even farther beyond its original purpose of sample management. Assay data management, data mining, data analysis, and electronic laboratory notebook (ELN) integration have been added to many LIMS, enabling the realization of translational medicine completely within a single software solution. Additionally, the distinction between LIMS and LIS has blurred, as many LIMS now also fully support comprehensive case-centric clinical data.

Aside from the key functions of sample management, instrument and application integration, and electronic data exchange, there are numerous additional operations that can be managed in a LIMS. Up until the late 1970s, the management of laboratory samples and the associated analysis and reporting were time-consuming manual processes often riddled with transcription errors. This gave some organizations impetus to streamline the collection of data and how it was reported. Custom in-house solutions were developed by a few individual laboratories, while some enterprising entities at the same time sought to develop a more commercial reporting solution in the form of special instrument-based systems.

In 1982 the first generation of LIMS was introduced in the form of a single centralized minicomputer, which offered laboratories the first opportunity to utilize automated reporting tools. As the interest in these early LIMS grew, industry leaders like Gerst Gibbon of the Federal Energy Technology Center in Pittsburgh began planting the seeds through LIMS-related conferences. By 1988 the second-generation commercial offerings were tapping into relational databases to expand LIMS into more application-specific territory, and International LIMS Conferences were in full swing. As personal computers became more powerful and prominent, a third generation of LIMS emerged in the early 1990s. These new LIMS took advantage of client/server architecture, allowing laboratories to implement better data processing and exchanges. By 1995 the client/server tools had developed to the point of allowing processing of data anywhere on the network. Web-enabled LIMS were introduced the following year, enabling researchers to extend operations outside the confines of the laboratory. From 1996 to 2002 additional functionality was included in LIMS, from wireless networking capabilities and referencing of samples, to the adoption of XML standards and the development of Internet purchasing. As of 2012, some LIMS have added additional characteristics that continue to shape how a LIMS is defined. Additions include clinical functionality, electronic laboratory notebook (ELN) functionality, as well a rise in the software as a service (SaaS) distribution model.

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Cover Story The LIMS is an evolving concept, with new features and functionality being added often. As laboratory demands change and technological progress continues, the functions of a LIMS will likely also change. Despite these changes, a LIMS tends to have a base set of functionality that defines it. That functionality can roughly be divided into five laboratory processing phases, with numerous software functions falling under each:  The reception and log in of a sample and its associated customer data  The assignment, scheduling, and tracking of the sample and the associated analytical workload  The processing and quality control associated with the sample and the utilized equipment and inventory  The storage of data associated with the sample analysis  The inspection, approval, and compilation of the sample data for reporting and/or further analysis

Image Credit: Ligolab.com

Aside from the key functions of sample management, instrument and application integration, and electronic data exchange, there are numerous additional operations that can be managed in a LIMS. This includes: Audit management fully track and maintain an audit trail barcode handling, assign one or more data points to a barcode format; read and extract information from a barcode chain of custody, assign roles and groups that dictate access to specific data records and who is managing them compliance follow regulatory standards that affect the laboratory customer relationship management handle the demographic information and communications for associated clients document management process and convert data to certain formats; manage how documents are distributed and accessed instrument calibration and maintenance schedule important maintenance and calibration of lab instruments and keep detailed records of such activities inventory and equipment management measure and record inventories of vital supplies and laboratory equipment manual and electronic data entry provide fast and reliable interfaces for data to be entered by a human or electronic component method management, provide one location for all laboratory process and procedure (P&P) and methodology to be used and managed as well as connecting each sample handling step with current instructions for performing the operation personnel and workload management, organize work schedules, workload assignments, employee demographic information, training, and financial information quality assurance and control gauge and control sample quality, data entry standards, and workflow reports, create and schedule reports in a specific format; schedule and distribute reports to designated parties time tracking calculate and maintain processing and handling times on chemical reactions, workflows, and more traceability show audit trail and/or chain of custody of a sample workflows. References

There are several pieces of core functionality associated with these laboratory processing phases that tend to appear in most LIMS:

As laboratory demands change and technological progress continues, the functions of a LIMS will likely also change. Despite these changes, a LIMS tends to have a base set of functionality that defines it.

 "2011 Laboratory Information Management: So what is a LIMS?".Sapio Sciences. 28 July 2010. Retrieved 7 November 2012.  Vaughan, Alan (20 August 2006). "LIMS: The Laboratory ERP". LIMSfinder.com. Retrieved 7 November 2012.  McLelland, Alan (1998). "What is a LIMS - a laboratory toy, or a critical IT component?" (PDF). Royal Society of Chemistry. p. 1. Archived from the original (PDF) on October 21, 2012. Retrieved 7 November 2012  Gibbon, G.A. (1996). "A brief history of LIMS" (PDF). Laboratory Automation and Information Management. 32 (1): 1– 5. doi:10.1016/1381-141X(95)00024-K. Retrieved 7 November 2012. The Cover story is covered by: Becky Scolastica Bello, Editorial team Microbioz India, Nigeria

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Medicall

Medicall: Chennai India’s largest B2B Medical equipment exhibition Story Source: Medicall

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edicall is India’s largest B2B Medical Equipment Exhibition is organized by Medexpert

"Medicall serves as a marketing platform wherein the equipment companies showcase their products and services to Hospital owners and decision makers.

2007: Medicall 2007 was bigger and better than its first edition. There were more exhibitors and visitors at the event. 2008: The third edition of Medicall attracted 5,400 visitors from across the country. Apart from hospital owners, hospital administrators, and people from other segments like dealers, architects, hospital consultancy, nurses, and biomedical engineers, exhibitors dealing with hospital flooring, lighting, energy saving equipment, storage solutions, ambulance fabricators, etc., also participated for the first time in this show.

Thus Medicall was born.

2009: With more than 5700 visitors attending Medicall 2009, the expo bridged the gap between the buyers and users and managed to bring them together on one single platform. In this three-day expo, more than 250 exhibitors from all over India and China displayed their latest equipment. Medicall became a pan-India event than just a regional expo in Chennai.

Business Consultants Pvt Ltd, promoted by Dr. Manivannan S, Joint Managing Director of Kauvery hospital a1000 bedded Hospital group in South India. Early in his career, he identified that nursing homes, small hospitals and clinics in tier 2 and 3 cities faced a distinct disadvantage in the market while procuring hospital equipment or service. They neither had the choice nor the price advantage enjoyed by the biggies. While talking about the motivation behind starting this expo, Dr Manivannan S says, "Small and medium sized hospital owners from tier II and III cities cannot afford to have qualified purchase managers. Equipment companies also do not have adequate sale force to meet all these hospital owners. Since I have undergone the difficulty for my hospital, I thought Medicall will bring in all equipment manufacturers under one roof.

Medicall shows are held at Chennai, Mumbai, Delhi, Ahmedabad, Kolkata, Hyderabad and Colombo since 2006. Medicall has completed 16 successful editions. Medicall Chennai 2016 had more than 750 exhibitors, 15000 professional visitors and over 5000 products. Medicall – the rise over the years 2006: The first Medicall exhibition was introduced as a small medical equipment expo and was hosted at Chennai. It was very well received by the industry and there were more than 100 exhibitors and 3000 visitors.

2010: Availability of unique products, choice of products, international exhibitors were the USPs of Medicall 2010.

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Medicall

It was bigger and more incisive in terms of content and participation. International participation increased and over 400 exhibitors from China, Germany, Taiwan, England and India displayed their latest medical equipment. It grew to become India's largest and Asia's third largest medical equipment expo. 2011: Around 7500 visitors from India and other countries like Sri Lanka, Nigeria, Nepal, and Taiwan visited the three day show. The Healthcare Innovation Awards, instituted for first time in this edition of Medicall, attracted several applications from across the country. More than 430 exhibitors from India, Germany, China, Taiwan, Korea, Japan and Iran participated in the show and displayed A-Z requirement of hospitals. 2012: Medicall 2012 was again a year to remember with huge participation from healthcare industry experts and professionals as well as several new and innovative segments like fashion show on hospital garments and “Hospital Property Mela�.

Over 500 companies exhibited at Medicall. It also saw an increase in exhibit space. Representatives from Germany, China, Taiwan, South Korea, Pakistan, Malaysia and more participated in Medicall events last year. 2013: With 530 Exhibitors and more than 10500 visitors, Medicall 2013 has grown in terms of quality and quantity. BrainStormMedicall conferences attracted more than 850 delegates with 8 parallel thematic healthcare conferences. 2014: Medicall 2014 involved approximately 630 companies from across the globe who participated in the exhibition. Most of the exhibitors substantially increased the size of their stall and showcased more products during the 3 day exhibition. It was a true bazaar for hospital equipment and supplies, ranging from surgical gloves to the most sophisticated medical equipment used worldwide.

This edition saw an increase in international exhibitors and subsequent booking of bigger stalls for this year. Medicall made its debut in Mumbai with 200 exhibitors and 7500 visitors. 2016: Medicall 2016 witnessed more than 750 exhibitors from across the globe and over 15000 visitors. Anexclusive IT pavilion was set where it showcased Products and services related to Healthcare IT. This year Medicall marked its presence in Delhi with 300 Exhibitors and 10000 Visitors. The US Commercial service organized a Successful 1-1 business Trade meet between manufacturers from US and dealers and distributors from India. Medicall 2016 at Chennai has become one of the largest shows in Chennai Trade Center, Chennai across industries. What are this year's highlights? What will be the 'never before' segments at the event this time?

2015: The 13th of Medicall featured around 700 international and national exhibitors, over 12500 visitors and 500 delegates.

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Medicall

This 17th edition, Medicall has become a truly international show, with International pavilions from Bavaria, Germany, Japan, China, Taiwan, Malaysia, South Korea, Portugal, Italy, UK, USA. This year the focus will be on Healthcare IT and 3D Printing. A pavilion for Healthcare IT is planned. The IT pavilion will bring out the best & the latest in Healthcare IT from Infrastructure to HMS to App Based solutions to innovative Tele-Medicine platforms. More than 6000 products from 20 countries will at display at Medicall Chennai 2016 – Jul 28 ,29 & 30 2017 The Profile of Visitors: 1. Doctors – Physicians & Surgeons 2. Hospitals owners & Decision Makers 3. Dealers Distributors & Manufacturers 4. Owners of Diagnostic & other Healthcare Centers 5. Medical Directors 6. Deans &Academicians

7. Biomedical Engineers 8. Key policy makers from the governmental sectors 9. Purchase 10. Managers 11. Healthcare Professionals 12. Healthcare Consultants 13. Importers 14. CIOs, CTOs, IT Managers 15. Hospitals planners, designers & architects 16. Nursing & Paramedical professionals Why should one attend Medicall Expo? Come July, the medical fraternity embarks on its annual pilgrimage to Chennai, the Mecca of the medical legion. A perfect getaway to meet one's peers, to compare and choose equipment and best of all to refresh the knowledge base in the intellectually stimulating BrainStorm Medicall. A favourite with Many International product companies, Medicall has these come repeatedly to

Widen their dealer and distributor base. Diversity is a given in this expo. Medicall provides a cost effective and accessible opportunity for healthcare entrepreneurs, management professionals and physicians of India. Top Reasons to Visit Medicall a) To buy Equipments / services for the Hospital / Clinic b) To get dealership from International Companies and reputed Indian companies c) To get the best and latest in Healthcare Industry d) To get updates on innovations in the field of Healthcare e) To meet collaborating partners f)

To get to know about the Healthcare Industry

g) To attend and participate in though provoking conferences and seminars h) To attend special 1-1 business meets

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Research News

Novel PET tracer directly detects small blood clots: Study he researchers in Germany have developed a fluorinebased tracer compound that can bind with high affinity to small clots, allowing doctors to image them using positron emission tomography (PET).

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Blood clots in veins and arteries can cause heart attacks and strokes which are the leading causes of mortality. Doctors often look for these clots using imaging techniques, so as to treat them or identify where thrombi are causing problems. Currently, imaging techniques frequently rely on spotting changes in blood flow, rather than imaging the clots themselves. Depending on the suspected location of a clot, different imaging techniques are needed, and it can be difficult to spot smaller clots, or damaged areas in blood vessels where there is a risk of clots forming. In this featured article published in The Journal of Nuclear Medicine's (JNM) July 2017 issue, German researchers have showed that targeting GPIIb/IIIa receptors, the key receptor involved in platelet clumping, with a fluorine-18 (18F) labeled ligand is a promising approach for diagnostic imaging. Andrew Stephens of Piramal Imaging, a researcher who was involved in the study said, “Currently available diagnostic techniques for blood clot imaging rely on different modalities depending on the vascular territory." “A single imaging modality that could visualize clots from various sources in different anatomic regions would be very valuable.” For this preclinical study, scientists successfully developed the novel small molecule tracer 18F-GP1 for positron emission tomography (PET) imaging that binds with high affinity to GPIIb/IIIa receptors.

18F-GP1 was found to accumulate at the site of thrombus formation, without its binding ability being affected by anticoagulants like aspirin and heparin. The tracer showed rapid blood clearance, and PET imaging in a Cynomolgus monkey model demonstrated the detection of small venous and arterial clots, endothelial damage and emboli in the brain. As favorable pre-clinical results were obtained, a first-inhuman study of 18F-GP1 is currently underway. Early results from an interim analysis confirm the preclinical data and were presented at the 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in June. In the context of this research, the researcher Stephens points out that, "Although the current studies are preliminary, 18FGP1 may provide not only more accurate anatomic localization, but also information of the risk of the clot growth or embolization.” "This may lead to changes in clinical intervention to the individual patient." Addressing the use of anticoagulants to treat blood clots, he notes, "These drugs can cause significant and life-threatening bleeding. There is a critical need to balance the risk of bleeding against the risk of clotting in each patient. 18F-GP1 may in the future assist in this important decision." Story Source: Society of Nuclear Medicine. Journal Reference: Jessica Lohrke, Holger Siebeneicher, Markus Berger, Michael Reinhardt, Mathias Berndt, Andre Mueller, Marion Zerna, Norman Koglin, Felix Oden, Marcus Bauser, Matthias Friebe, Ludger M. Dinkelborg, Joachim Huetter, Andrew W. Stephens. 18 F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi. Journal of Nuclear Medicine, 2017; 58 (7): 1094 DOI: 10.2967/jnumed.116.188896

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Research News

Scientis ts report new limits to function al DNA element s of human genome Research suggests at least 75 percent of the genome is junk DNA ccording to the new calculations by an evolutionary biologist, it has been reported that no more than 25 percent of the human genome is functional. This shows the sharp difference to what the scientists with the ENCODE project has suggested earlier that as much as 80 percent of the genome is functional.

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The research work showing the new calculations by the evolutionary biologist at the University of Houston has been published online in the journal Genome Biology and Evolution.

Using that information, Graur created a model to calculate the decrease in reproductive success induced by harmful mutations, known as the "mutational load," in relation to the portion of the genome that is functional.

Because of deleterious mutations, each couple in each generation must produce slightly more children than two to maintain a constant population size.

In the research, the biologist Dan Graur has reported that the functional portion of the human genome probably falls between 10 percent and 15 percent with an upper limit of 25 percent. The rest of the genome is the junk DNA which is of no use but harmless DNA. During the research, Graur, John and Rebecca Moores Professor of Biology and Biochemistry at UH made use of a simple approach to find out how much of the genome is functional, using the deleterious mutation rate - that is, the rate at which harmful mutations occur - and the replacement fertility rate. Both genome size and the rate of deleterious mutations in functional parts of the genome have previously been determined, and historical data documents human population levels.

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The functional portion of the genome is defined as that which performs a selected-effect function, that is, a function that arose through and is maintained by natural selection. Some example of selected-effect functons are protein-coding genes, RNAspecifying genes and DNA receptors. In his model, only functional areas of the genome can be damaged by deleterious mutations; mutations in non-functional portions are neutral since functionless portions can be neither damaged nor improved. Because of deleterious mutations, each couple in each generation must produce slightly more children than two to maintain a constant population size. Over the past 200,000 years, replacement-level fertility rates have ranged from 2.1 to 3.0 children per couple, he said, noting that global population remained remarkably stable until the beginning of the 19th century, when decreased mortality in newborns resulted in fertility rates exceeding replacement levels. If 80 percent of the genome were functional, unrealistically high birth rates would be required to sustain the population even if the deleterious mutation rate were at the low end of estimates, Graur found. He further wrote that "For 80 percent of the human genome to be functional, each couple in the world would have to beget on average 15 children and all but two would have to die or fail to reproduce. If we use the upper bound for the deleterious mutation rate (2 Ă— 10^8 mutations per nucleotide per generation), then the number of children that each couple would have to have to maintain a constant population size would be higher than the number of stars in the visible universe by ten orders of magnitude." In 2012, the Encyclopedia of DNA Elements (ENCODE) announced that 80 percent of the genome had a biochemical function. Graur said this new study not only puts these claims to rest but hopefully will help to refocus the science of human genomics.

MANAGED WITH US

"We need to know the functional fraction of the human genome in order to focus biomedical research on the parts that can be used to prevent and cure disease," he said. "There is no need to sequence everything under the sun. We need only to sequence the sections we know are functional." Story Source: University of Houston. Journal Reference: Dan Graur. An upper limit on the functional fraction of the human genome. Genome Biology and Evolution, 2017; DOI: 10.1093/gbe/evx121

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Research News

Tomatoes rich diet is found to cut skin cancer in half in mice Discovery done on the basis of previous evidence of cancerprevention benefits

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he scientists of The Ohio State University have reported that daily tomato consumption can cut the development of skin cancer tumors by half in a mouse study

This new study showing how nutritional interventions can change the risk for skin cancers has been published online in the journal Scientific Reports. The study involved feeding the male mice with a diet rich in tomatoes, to be specific diet rich in 10 percent tomato powder daily for 35 weeks, and then exposing them to ultraviolet light. The researchers noticed an average of a 50 percent decrease in skin cancer tumors compared to mice that ate no dehydrated tomato. This relationship between tomatoes and treating cancer was based on a previous theory that dietary carotenoids, the pigmenting compounds that give tomatoes their color, may protect skin against UV light damage, according to Jessica Cooperstone, co-author of the study and a research scientist in the Department of Food Science and Technology in the College of Food, Agricultural, and Environmental Sciences at Ohio State. The research did not show any significant differences in tumor number for the female mice in the study. Previous research has shown that male mice develop tumors earlier after UV exposure and that their tumors are more numerous, larger and more aggressive. In the context of this study, the study's senior author and a professor of pathology and member of Ohio State's Comprehensive Cancer Center Tatiana Oberyszyn said,

"This study showed us that we do need to consider sex when exploring different preventive strategies. What works in men may not always work equally well in women and vice versa." The clinical trials based on the previous research on the subject suggest that eating tomato paste over time can diminish the effect of sunburns, perhaps due to the deposition of the carotenoids from the plants in the skin of humans after eating, and this may be able to protect against UV light damage, said Cooperstone. The research also showed that a primary carotenoid in tomatoes named Lycopene is the most effective antioxidant of these pigments. "However, when comparing lycopene administered from a whole food (tomato) or a synthesized supplement, tomatoes appear more effective in preventing redness after UV exposure, suggesting other compounds in tomatoes may also be at play." In the new study, the scientists at the Ohio State reported that only male mice fed dehydrated red tomatoes showed significant reductions in tumor growth. Those fed diets with tangerine tomatoes, which have been shown to be higher in bio available lycopene in previous research, had fewer tumors than the control group, but the difference was not statistically significant. Story Source: Ohio State University. Journal Reference: Jessica L. Cooperstone, Kathleen L. Tober, Ken M. Riedl, Matthew D. Teegarden, Morgan J. Cichon, David M. Francis, Steven J. Schwartz, Tatiana M. Oberyszyn. Tomatoes protect against development of UVinduced keratinocyte carcinoma via metabolomic alterations. Scientific Reports, 2017; 7 (1) DOI: 10.1038/s41598-017-05568-7

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EVENTS

DATES/YEAR

28th to 30th July & October 6th to 8th / 2017 Chennai

VENUE

Chennai / Mumbai

11th to 12th August / 2017

Hyderabad

6th to 8th September / 2017

Thailand

6th to 8th October / 2017

Mumbai

5th to 7th October / 2017

Ahmedabad

14th to 16th December / 2017

Nepal

16th to 18th March / 2018

Mumbai

26th Feb to 1st March / 2018

USA

2nd to 4th April / 2018

Singapore

11th to 15th June / 2018

Germany

16th to 18th August / 2017

China

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Product Launch

Cole-Parmer® Launches ThinTouchPROtect™ Nitrile Gloves Proven protection against cytotoxic chemicals, microbes and viruses ole-Parmer, a leading global source of laboratory and industrial products, equipment and supplies since 1955, recently launched ThinTouchPROtect™ Nitrile Gloves – a line extension of company’s ThinTouch™ range of gloves. Specially formulated, designed and tested to stringent standards, the gloves provide user with maximum assurance, superior comfort and enhanced tactility.

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These gloves offer highest protection against many risks than any other glove in the category. They are tested against 29 chemotherapeutic drugs as per ASTM D 6978-05.They have exceptional breakthrough time even for Carmustine (3.3 mg/ml) – 127.5 mins and ThioTepa (10.0 mg/ml) – 240 mins where other gloves have failed. Manufactured using a unique formulation - they undergo series of exhaustive tests to ensure these are the best in the category. The gloves are highly chemical resistant and are qualified for oncology production and research applications. The anti-static property with resistivity of 1X107 Ohms at humidity 51% makes these gloves an ideal choice in processes demanding low electrostatic discharge.

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The glove has a great tactile feel for wearer comfort over extended period of use. Its unique color provides visual differentiation from other natural rubber latex and synthetic gloves. ThinTouchPRotect Nitrile Gloves are available in 9.5” and 12” length and S to XL sizes. These are ambidextrous with beaded cuffs ensuring ease of donning and have textured fingertips for enhanced wet or dry grip. The gloves have lowparticulates to prevent glove-related work contamination. View Cole-Parmer’s full selection of Nitrile and Latex Gloves at www.coleparmer.in For sampling requests/placing orders or to know more about this product, please contact Cole-Parmer Application Specialist at 022-61394444, e-mail response@coleparmer.in or visit www.coleparmer.in



Product Launch

Low-Volume Storage Tube for Genomic Applications Micronic, Lelystad, the Netherlands, has launched a 0.30 mL tube with external thread that enables miniaturization of reaction volumes required in genomic applications. The tube eliminates the need for intermediate screening plates and is designed to be more accessible for low-volume liquid handlers.

Calibrated electronic verification Lollipop Stem thermometers from Bel-Art–SP Scienceware, Wayne, NJ, are compact, all-inone units with the display attached directly to the probe rather than with a cable. The entire digital unit can be placed inside a refrigerator, incubator, or room to verify sample temperatures. Available with general calibration, or with calibration specific to refrigerators, incubators, or ambient temperatures, the Lollipop Stem thermometers are supplied with calibration documents that meet the requirements of ISO 17025. For more information, visit BelArt–SP Scienceware

In addition, an automation-friendly 0.30 mL tube, with a working volume of 210 µL, is ideal for RNA/DNA libraries, offering unique a liquoting and storage capacity with multi-access. After the company’s 1.40 mL and 0.75 mL tubes, the 0.30 mL tube is the next size in a range of new designs featuring an external thread. Using externally threaded tubes for sample storage eliminates the possibility of the sample coming into contact with the screw thread, reducing the chance of crosscontamination while improving sample integrity. Due to thick tube walls, the tube has a sturdy design and excellent properties for ultra-low temperature storage.

Quanterix Launches Multiplex Panel to Study TBI Severity Quanterix Corp, Lexington, Mass, has launched the Simoa Neurology 4-Plex A assay (N4PA). The Simoa N4PA assay can simultaneously measure four protein biomarkers from either cerebrospinal fluid (CSF) or directly from blood samples for the study of traumatic brain injury (TBI) and other neurodegenerative conditions. The four biomarkers used on the panel include neurofilament light (NF-L), tau, glial fibrillary

Cable-Free Sample Temperature Verification

acidic protein (GFAP), and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1). References: The story source of above contents are prepared for information purposes for more information follow the site : www.clpmag.com and www.labbulletin.com

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