Paper-Thin Wound Care Second Only to Skin
NanoDerm Nano Derm
Revolutionary Technology Equals High-Performance Healing
Manufactured by ZBX Corporation under license from Axcelon Biopolymers Corporation
Reduces total treatment costs (hospital, physician, patient and societal) • Decreased hospitalization time, the need for analgesics and antibiotics •
Natural and biocompatible •
Contains no adhesives and when moistened resembles human skin
Non-traumatic to wound edges
Improves healing time through acceleration of wound closure1,2
Reduces electrolyte and protein loss by adhering firmly to the skin
Reduces pain which leads to more patient comfort
Selective permeability (retains fluids, but allows perspiration) 3,4
Bacterial barrier
Transparent film allowing the wound to be examined without removal of the dressing
•
Protects the wound area by preventing the passage of common bacterial pathogens found on the skin5
Biodegradable, non-toxic, nonpyrogenic, sterile and hypoallergenic
Stable at room temperature with long shelf life
After epidermal regeneration, the film detaches spontaneously. No adhesives means its removal is painless and does not damage the underlying epithelium.
NanoDerm_DetailAid_Oct22_1.7.indd 1
info@nanoderm.ca
The One-time Dressing Application in Wound Care References 1. Slezak A, Kucharzewski M, Franek A, Twardokes W. Evaluation of the efficiency of venous leg ulcer treatment with a membrane dressing. Med Eng Phys. 2004; 26(1):53-60. 2. Solway DR, Clark WA, Levinson DJ. A parallel open-label trial to evaluate microbial cellulose wound dressing in the treatment of diabetic foot ulcers. Int Wound J. 2011; 8(1):69-73. 3. Czaja WK, Young DJ, Kawecki M, Brown RM Jr. The future prospects of microbial cellulose in biomedical applications. Biomacromolecules 2007; 8(1):1-12. 4. Fontana JD, de Sousa AM, Fontana CK, et al. Acetobacter cellulose pellicle as a temporary skin substitute. Appl Biochem Biotechnol. 1990; 24-25:253-264.
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Easy to apply and highly absorbent
Single application. It’s clear.
ZBX Corporation 9-73 Railside Road, Toronto, Ontario M3A 1B2
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5. Wei B, Yang G, Hong F. Preparation and evaluation of a kind of bacterial cellulose dry films with antibacterial properties. Carbohydr Polym. 2011; 84:533-538.
MADE IN CANADA
MADE IN CANADA
nanoderm.ca
Indicated for the treatment of wounds and second-degree burns
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One-time, easy application eliminates the need for replacement dressings
Introducing
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Acts like a second skin to heal burns and wounds, and has many unique features and benefits:
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nanoderm.ca
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The Next Generation in Wound Care
Accelerates Wound Closure
Wound Closure Acceleration and Cost Reduction are the Key Benefits
Venous Leg Ulcers
Diabetic Foot Ulcers
Superior to Hydrocolloid Dressing1,*
Superior to XeroformTM Occlusive Petrolatum Gauze (3% Bismuth Tribromophenate) 2,†
Made from bacterial cellulose, NanoDerm , a microfibrillar biosynthetic cellulose film, is the one-time single-application wound care product that simulates the skin’s natural defenses (fibrin) to help promote quicker wound healing. ®
•
Highly absorbent
•
Helps protect against bacterial infections
•
Eliminates the frequency of dressing replacement, leading to a reduction of the overall cost of treatment for healthcare facilities
42 Days
30.00
84 Days SD 0.125 (n=31)
20.00
126 Days SD 0.125 (n=31)
10.00
Bacterial Cellulose
3
1
2
80
0.00
Revolutionary Technology Accelerates Wound Closure •
•
The pore size created by the microfibrils and ribbons of the paper-thin membrane trap platelets and initiate coagulation, bringing about both haemostasis and adherence to the wound surface
The greater absorptive capacity of the membrane and its porous nature allow for the dissipation of exudate while maintaining a moist wound interface
NanoDerm_DetailAid_Oct22_1.7.indd 2
•
•
Acts as a regenerative tissue scaffold to affect fibroblast, endothelial and keratinocyte function, enhancing granulation tissue formation and epithelization The tensile strength of the material allows it to remain in place for longer periods with little need for dressing change
Treatment Initiated
After 7 Days of Treatment
Treatment Almost Finished
July 24, 2006
July 31, 2006
August 3, 2006
16 Days 32 Days 48 Days SD 2.5 SD 4.7 (n=15) (n=19)
60
40
Diabetic Foot Ulcers
40.00
80.00
April 5, 2006 0
t [day]
April 19, 2006
August 6, 2006
August 11, 2006
Xeroform MC dressing 0
120.00
2nd Degree Burns
20
0.00
1,2
Venous Leg Ulcers
100
Percent original wound size
Reduces pain
40.00
Sbp [cm2]
•
Fibrin
Demonstrated Clinical Efficacy ‡
20
40
60
80
100
Treatment time (days)
Adapted from Slezak A, et al. Med Eng Phys. 2004; 26(1):53-60.1
Adapted from Solway DR, et al. Int Wound J. 2011; 8(1):69–73.2
* Randomized, open-label trial to evaluate BioCellulose Membrane dressing in the treatment of venous leg ulcer (n=93). Groups 1 and 3 were treated with BioCellulose Membrane dressing, and Group 2 was treated with Hydrocolloid Dressing. S bp = Ulcer Surface (p<0.005).1
†
A parallel, randomized, open-label trial to evaluate Microbial Cellulose (MC) wound dressing in the treatment of diabetic foot ulcers (n=34). The mean time to heal in the MC (±SE)-treated group was 32 days ± 2.5 and for controls it was 48 days ± 4.7 (p< 0.01). Rate of weekly wound closure (mean ± SE) was 1.7 times faster in the MC-treated group (p<0.001).2
‡
Data from clinical case studies
Indications Diabetic foot ulcers
Venous ulcers
Pressure ulcers
Donor site
Acute wounds
Dermabrasion
2014-10-22 9:53 AM