P032

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SYNTHESIS AND CHARACTERIZATION OF SILVER/MONTMORILLONITE/CHITOSAN BIONANOCOMPOSITES BY CHEMICAL REDUCTION METHOD AND THEIR ANTIBACTERIAL ACTIVITY

THE DISCOVERY

1.0% (a(a-b)

2.0% (c(c-d)

SEM micrographs and EDXRF spectra for the MMT (a, b) and MMT/Cts (c, d).

The Silver nanoparticles (Ag NPs) were successfully prepared from the AgNO3/MMT/ Chitosan suspension at the different AgNO3 concentration by using sodium borohydride. The antibacterial activities of Ag/MMT/Cts at the different particle size of Ag NPs were showed a strong antibacterial activity against the grampositive and gram-negative bacteria.

5.0% (c(c-d) 5.0% (A4) 2.0% (A4) 1.5% (A3) 1.0% (A2) 0.5% (A1) MMT

TEM images and corresponding particle size distribution of Ag/MMT/Cts BNCs.

IMPORTANCE

SEM micrographs and EDXRF spectra respectively for the Ag/MMT/Cts BNCs.

The antibacterial activity of Ag NPs containing materials that can be used, for example, in medicine to reduce infections in human skin, dental materials, catheters, vascular grafts, stainless steel materials, arthroplasty and burn treatment, as well as to avert microorganisms colonization on prostheses.

PXRD patterns of MMT, Ag/MMT/Cts BNCs for determination of silver crystals.

Comparison of the inhibition zone test between gram gram--negative and gramgram-positive bacteria.

In addition, nanomaterials including Ag NPs can be utilized for water treatment and also for reducing bacteria on textile fabrics. Ag NPs also demonstrate an effective cytoprotective activity towards HIV infected cells.

METHODOLOGY

IMPACT

Micro Organism

bandage

paints

packaging

Cosmetics

tooth

Protective agent

Antibacterial

Project Leader : Dr. Kamyar Shameli Co-Researcher : Prof. Dr. Mansor Bin Ahmad, Wan Md Zin Wan Yunus, Nor Azowa Ibrahim Department/Lab : Department Chemistry Faculty : Faculty of Science, Universiti Putra Malaysia Email : kamyarshameli@gmail.com

Tissue

Kamyar Shameli, Mansor Bin Ahmad, Synthesis and characterization of silver/montmorillonite/chitosan bionanocomposites by chemical reduction method and their antibacterial activity. International Journal of Nanomedicine. 2011, 6, 271-284. (IF 2011= 4.976, Q1)

Project Leader Expertise : Science/Chemistry/Polymer group Tel : +603 8946 6793


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