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A Troubling Connection Between Justice System Involvement and Child Health By Jeb Phillips A first-of-its kind study, published in , finds that while only 2% of patients at a large children’s hospital are identified with likely personal or family involvement in the justice system, they account for large proportions of some troubling diagnoses. PediatricsNationwide.org/troubling-connection-health-justice
Unraveling the Role of Pioneer Factors in Childhood Cancer By Abbie Roth Transcription factors are proteins that read the DNA sequences and can direct the transcription of that sequence into mRNA for translation into a protein. Transcription can become deregulated in cancer. Pioneer factors are transcription factors that can read and manipulate “closed” or inaccessible chromatin. A new study from Ben Stanton, PhD, in the Center for Childhood Cancer and Blood Diseases, shows that the oncogenic transcription factor PAX3-FOXO1 is present and acting as a pioneer factor in the context of the rare childhood cancer rhabdomyosarcoma. PediatricsNationwide.org/role-of-pioneer-factors-in-childhood-cancer
Alarming Upward Trend in Black Youth Suicide From 2003 to 2017 Written by Lauren Dembeck, PhD For the first time, researchers have examined the trends and precipitating circumstances of suicide in Black youth only by age group and sex. The study, published in the Journal of the American Academy of Child and Adolescent Psychiatrists, identified specific risk factors and developmental mechanisms associated with Black youth suicide that could serve as targets in suicide prevention programming. PediatricsNationwide.org/Black-youth-suicide-influences
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PediatricsNationwide.org | Fall/Winter 2021
