Newgate Health September 2023 Edition

HEALTH

IN THIS MONTH’S EDITION

PERSONALISED MEDICINE MEETS COSMETICS

THE HEALTH DIARIES

INTERESTING HEALTH AND WELLNESS NEWS FROM AROUND THE WORLD

ALSO INCLUDED IN THIS EDITION

LATESTHEALTHNEWS

NAVIGATING AUTUMN'S CHALLENGES AND EFFECTIVE COPING STRATEGIES

CHALLENGES FACED BY WOMEN IN THEIR MID-20S

THE INTERCONNECTION BETWEEN THE GUT AND THE BRAIN

HARNESSING BEE PRODUCT BENEFITS FOR CHILDREN'S DEVELOPMENT

PERSONALIZED MEDICINE MEETS COSMETICS: GENETIC PROFILING FOR TAILORED SKINCARE REGIMENS

ANDALOTMORE!

DearReaders,

Welcome to the September edition of Newgate Health - the monthly magazine that brings you the latest news in the healthandwellnessworld.Ourpreviousissueswereasuccess and we are happy to be back this month with new and interesting content to share with health and wellness enthusiasts.

For this September 2023 edition, the Newgate team has worked hard to bring you the most original and interesting articles on everything health and wellness, including everything you need to know about navigating autumn's challenges and effective coping strategies as well as challengesfacedbywomenintheirmid-20s.You’llfindarange oftopicsthatwillhopefullymotivateyoutohoponthehealth trainwithus!

In this edition, we also want to give you insights on the interconnection between the gut and the brain together with topics on personalised medicine meets cosmetics: genetic profilingfortailoredskincareregimens

As always, we thank all our readers for their interest and valuable feedback, and we look forward to your continuous engagement with our magazine. If you enjoy this magazine, feel free to share it with your friends and colleagues, and any feedbackisalwayswelcome.

TheNewgateHealthTeam

ESSENTIAL ENERGY

NOMATTERYOURPROFESSIONORPASTIME, YOUOFTENFINDYOURSELFDEMANDINGMORE.

WEAREANASPIRATIONALSPECIES,ONETHAT THRIVESONSETTINGRECORDSANDSMASHING OUROWNRESULTS–ASWELLASTHOSEOF OURCOMPETITORS.

ATNEWGATE,WEUNDERSTANDHOWENERGY WORKS.EACHHYDRAULICSFLAVOURISA CAREFULCONCOCTIONTHATBLENDSFLAVOUR ANDFEROCITYINTOAPERFECTMEDLEY.

THERESULTISADELICIOUSDRINKTHAT ENABLESYOUTODELIVERMORE.

NOTHING LESS THAN WONDERFUL

WWW.WEAREWONDERFUL.CO.UK

We Are Wonderful

Our eclectic selection of luxurious lotions, serums and face washes have been dreamt up by our in-house skincare experts to bring you beauty in bottled form. Experience Wonderful and discover new vitality in skin and soul alike.

www.WeAreWonderful.co.uk

NAVIGATING AUTUMN'S CHALLENGES AND EFFECTIVE COPING STRATEGIES

Additionally, light therapy boxes that simulate sunlight can be beneficial for those with more pronounced mood changes, such as SAD.

Sleep Routine Optimization

Sleep routine is essential for managing the disrupted sleep patterns that often accompany the transition to autumn. Establishing a consistent sleep schedule—going to bed and waking up at the same times each day—helps regulate the body's internal clock. Creating a calming pre-sleep routine, which might include reading, gentle stretching, or meditation, signals to the body that it's time to wind down. Minimizing exposure to screens before bedtime is crucial, as the blue light emitted by devices can suppress the production of melatonin, a hormone that aids in sleep.

Indoor Exercise Regimen

With the decrease in outdoor physical activities due to colder weather, developing an indoor exercise regimen is paramount. Regular exercise is not only beneficial for maintaining physical fitness but also for improving mental well-being. Indoor workouts, such as home-based aerobics, yoga sessions, or bodyweight exercises, offer effective alternatives to outdoor activities.

Engaging in physical activity releases endorphins—natural mood lifters—promoting a positive outlook and reducing stress levels. For those seeking structured routines and social interaction, joining a local gym or participating in virtual fitness classes can offer both exercise and a sense of community.

As the vibrant colors of summer give way to the golden hues of autumn, it's important to recognize the potential challenges that this seasonal shift brings. By understanding the difficulties associated with the onset of autumn and implementing effective coping strategies, individuals can navigate this transition with grace and resilience. The strategies discussed in this article—embracing light exposure, optimizing sleep routines, maintaining an indoor exercise regimen, practicing mindful eating, and employing stress

techniques—empower individuals to address challenges head-on.

Autumn's difficulties need not overshadow its inherent beauty and charm. By proactively taking care of physical, emotional, and mental well-being, individuals can fully embrace the season's transformations. Just as trees shed their leaves in preparation for a period of renewal, individuals can shed unhelpful habits and embrace personal growth.

Autumn, with its lessons of change and adaptability, can be a time of transformation and self-improvement. Through a holistic approach to well-being, autumn becomes not just a season, but a journey of self-discovery and renewal.

WOMEN

CHALLENGES FACED BY WOMEN IN THEIR MID-20S

settle down, often fueled by societal expectations, can lead to feelings of inadequacy and stress. Balancing

friendship evolution. As life paths

friendships can become challenging. Balancing work, personal growth, and maintaining connections may

Mental Health and Well-being

experience an array of mental health

depression, and identity crises. The pressures of transition, comparison with peers, and societal expectations

Self-Care and Coping Mechanisms

Promoting self-care and developing

Encouraging open conversations

professional support when needed, and cultivating self-compassion can mental

Societal Expectations and Identity

Societal Pressures

Societal expectations often dictate timelines for milestones such as marriage, homeownership, and career success. These societal pressures can lead to feelings of inadequacy and a sense of falling short. It's essential to recognize that personal journeys are unique and cannot be measured by external benchmarks.

Identity Exploration

The mid-20s are a prime time for identity exploration. Women often reflect on their values, interests, and passions, leading to the pursuit of authentic lives. Embracing this journey of self-discovery and granting oneself permission to evolve is key to personal growth and fulfillment.

The challenges that women face in their mid-20s are complex and multifaceted. Recognizing and addressing these challenges requires a collective effort from individuals, families, communities, and society at large. By fostering supportive environments, promoting mental health awareness, and embracing the diversity of personal journeys, we can empower women to navigate this transformative period with resilience, confidence, and a sense of purpose. The mid-20s can be a time of immense growth, and by addressing the challenges head-on, we pave the way for a brighter future for all.

INTERESTING

Ireland to introduce alcohol label health warning

Managing chronic inflammation with psoriasis

The Republic of Ireland is set to become the first country in the world to introduce health warning labels on alcohol products.

Stephen Donnelly, the Irish minister for health, signed new regulations into law on Monday but they will not come into force until 2026.

Labelling will warn consumers about the risks of drinking alcohol as well as providing a product's calorie content. The Irish government said the regulations would bring alcohol products into line with requirements for food packaging. Mr Donnelly said: "I welcome that we are the first country in the world to take this step and introduce comprehensive health labelling of alcohol products.

Read more on BBC

New research published in the journal Neurology shows that regular exercise may offer some benefits against Parkinson’s disease.

Read more on Medical News Today

In people with psoriasis, immune system dysfunction causes inflammatory cells to build up in the middle layer of the skin, known as the dermis. The condition also speeds the growth of skin cells in the epidermis, the outer skin layer.

Typically, skin cells grow and flake off in the span of a month. This process speeds up to just a few days in people with psoriasis. Instead of shedding, skin cells pile up on the skin’s surface, leading to uncomfortable symptoms such as raised plaques, scales, swelling, and redness or discoloration.

Read more on Mirror

WHYCHOOSE HYDRAULICS?

ATNEWGATE,WEHOLDDECADESOF COLLECTIVEEXPERIENCEINCREATING CONSUMABLESTHATADDRESSTHEDEMANDS OFTHEPUBLICWHILEPROTECTINGTHEIR HEALTH.

HYDRAULICSISNOTJUSTANOTHERENERGY DRINKTOBEFOUNDINYOURLOCALSHOP. EACHFLAVOURISCAREFULLYCONCOCTED USINGTHELATESTINNOVATIONSAND INCLUDESZEROJUNK.

WHENYOU’REPERFORMINGATTHEEDGEOF POSSIBILITY,YOUCANNOTPUTANYOLDCRAP INYOURBODY.OURDRINKSAREASNATURAL ASTHEYCANBE,CONSIDERINGTHE MONSTROUSPOWERTHEYPROVIDE.

DRINKRESPONSIBLY–THERE’SALOTOF POWERINEACHCAN!

THE INTERCONNECTION BETWEEN THE GUT AND THE BRAIN

In this discourse, we delve into an intriguing topic of considerable importance, one that some are well-acquainted with while others may not yet be fully aware—the profound interrelation between the gut and the brain, commonly known as the "Gut-Brain Connection." In today's world, an increasing number of individuals recognize the vital significance of the foods they consume in safeguarding their gut health. Allow us to elucidate the intricacies of this connection, shedding light on how the gut's influence extends to the realm of brain function.

The Gut-Brain Axis: Understanding the Link

The gut occupies a pivotal role within the human body, often referred to as the "second brain." This is due to its connection with the primary brain through a dynamic pathway known as the "gut-brain axis." This axis facilitates bidirectional communication, enabling signals to traverse between the gut and the brain. Integral to this connection is the enteric nervous system (ENS), a component of the gastrointestinal (GI) tract with its own neural network.

A Closer Look at the Gut and Brain Connection

The Enteric Nervous System (ENS)

The enteric nervous system (ENS) is an intricate automimic network that regulates gastrointestinal muscle activity, significantly influencing digestion. Remarkably, the ENS consists of an impressive count ranging from 200 to 600 million nerve cells.

The Role of the Vagus Nerve

The physical connection between the brain and gut finds its anchor in the vagus nerve—a substantial cranial nerve extending from the brain to the colon.

This nerve facilitates communication with sensory components that monitor organ impulses, including those originating from the gut microbiome. The vagus nerve's optimal functionality is paramount, as its well-being directly impacts the efficacy of communication between the brain and the gut.

Impact of Disrupted Communication

Disruptions in the communication between the gut and brain can lead to heightened sensitivity to stimuli, often resulting in unexpected discomfort. Factors such as stress, inadequate diet, and exposure to toxins contribute to this breakdown. The body's responsiveness to stimuli, which typically would not be perceived as painful, underscores the intricate relationship between the gut and brain.

The Nexus of Neurotransmitters

Neurotransmitters and Their Significance

The profound interplay between the gut and brain is facilitated by neurotransmitters, chemical messengers that transmit signals throughout the nervous system. The brain communicates messages to different parts of the body via these neurotransmitters, directing essential functions.

The Role of the Gut Microbiome

Within the gut microbiome, numerous neurons are engaged in active communication, establishing a neural "hotspot." Neurotransmitters travel along the vagus nerve, ensuring ongoing communication between the gut microbiome and the brain. This intricate intercommunication system mirrors the central nervous system neurotransmitter-based interactions.

Synthesizing Neurotransmitters

The gut and brain are replete with approximately 20 to 30 distinct neurotransmitters, with the gut microbiome boasting a similar diversity. Serotonin, often referred to as the "happy chemical," holds a pivotal role in both systems. Notably, about 90% of serotonin production occurs within the gut microbiome. A decline in serotonin production due to factors like stress and unhealthy lifestyles can have cascading effects, impacting mood and gut motility.

The Role of Gut Bacteria in Neurotransmitter Synthesis

Bacteria inhabiting the gut contribute significantly to the synthesis and modulation of key neurotransmitters. These include:

- GABA (Gamma-aminobutyric acid)

- BDNF (Brain-derived neurotrophic factor)

- Norepinephrine

- Dopamine

- Melatonin

- Acetylcholine

Collectively, these neurotransmitters and gut microbiomes exert substantial influence over the development of the enteric nervous system (ENS), the central nervous system, and the immune system. Their orchestrated interplay highlights the intricate nexus between the gut and brain, underscoring its importance in holistic well-being.

In conclusion, the remarkable connection between the gut and brain extends far beyond mere bodily functions—it encompasses a symphony of neural communication that shapes both physical and cognitive development. As we further explore this intricate relationship, a clearer understanding emerges of the role that our choices, from diet to lifestyle, play in nurturing this profound interconnection.

NEVER

Take care of your body, it’s the only

A healthy lifestyle is something we refine over time – not overnight.

Today I will do what others won’t, so tomorrow I can accomplish what

Never say the sky’s the limit when there are footprints on the moon.

The body achieves what the mind

It never gets easier. You just get

If you cannot do great things, do

HARNESSING BEE PRODUCT BENEFITS FOR CHILDREN'S DEVELOPMENT

The potential benefits of bee products extend beyond their traditional uses, offering a holistic approach to supporting children's development. These natural treasures, which include honey, propolis, bee pollen, and royal jelly, encompass a diverse array of nutrients and bioactive compounds that can positively impact various aspects of children's growth, immunity, cognitive function, and overall well-being.

Honey, a beloved and versatile bee product, holds promise in enhancing children's development. Its natural sugars provide a quick and sustained energy source, making it an ideal addition to their diets. Beyond its sweetness, honey contains an array of vitamins, minerals, and antioxidants that can contribute to their overall health. Moreover, honey's antimicrobial properties have the potential to support children's immune systems, aiding them in resisting common infections and promoting a healthy start in

Propolis, often referred to as nature's defense compound, showcases remarkable antioxidant and anti-inflammatory properties. As children explore the world around them, their immune systems are continually challenged. The bioactive compounds in propolis may support their immune responses, bolstering their ability to thrive in various environments. By incorporating propolis into their routines, caregivers may contribute to their children's resilience against health challenges and promote their

Bee pollen, a nutrient-dense mixture of pollen, nectar, and bee secretions, holds potential as a nutritional powerhouse for children. With its diverse array of vitamins, minerals, enzymes, and proteins, bee pollen aligns with the nutritional needs of growing bodies.

As children engage in various activities that demand energy and vitality, the nutrients found in bee pollen may contribute to their physical growth and overall development.

Royal Jelly

Royal jelly, a secretion fed to bee larvae destined for queenship, is a remarkable substance rich in nutrients. It contains proteins, lipids, vitamins, and minerals that are essential for growth and vitality. While research on its impact on children's development is still emerging, the unique compounds in royal jelly suggest potential benefits for cognitive function and overall well-being. By offering royal jelly in an appropriate form, caregivers may support their children's cognitive growth and vitality.

Scientific Insights and Traditional Wisdom

The exploration of bee products' effects on children's development draws upon both scientific insights and traditional wisdom. Although scientific research on this topic is ongoing, historical use and preliminary studies offer promising insights into the potential benefits of these products. The nutritional richness and bioactive compounds found in bee products align with the nutritional needs of growing children. While further research is needed, the tradition of using bee products for various health benefits underscores their potential significance in nurturing children's growth and well-being.

Integrating Bee Products into Children's Diets

When considering the integration of bee products into children's diets, caregivers must be attentive to their unique needs and sensitivities. While bee products offer potential benefits, they should be introduced cautiously and in age-appropriate forms. As with any dietary change, it's advisable for parents to consult healthcare professionals, particularly when dealing with allergies or specific health concerns.

Conclusion

Children's development is a multifaceted journey that demands attention to various aspects of growth and well-being. Bee products, with their nutrient-rich profiles and potential bioactive compounds, present a natural avenue for supporting children's development. While scientific research continues to unveil the specific mechanisms, the timeless tradition of using bee products highlights their potential significance in promoting children's growth, immunity, cognitive function, and overall health.

In conclusion, bee products offer a promising and natural approach to enhancing children's development, though thoughtful consideration and professional guidance are paramount. By exploring the potential benefits of bee products and making informed choices, caregivers and parents can contribute to their children's holistic growth and vitality. As we continue to uncover the intricate connections between nutrition, nature, and development, the role of bee products in nurturing healthy, thriving children is a realm of exploration with substantial promise.

PERSONALIZED MEDICINE MEETS COSMETICS

GENETIC PROFILING FOR

TAILORED SKINCARE REGIMENS

This trove of genetic data finds translation into tangible insights for skincare formulation and product development. A burgeoning trend involves weaving genetic test results into personalized skincare recommendations, redefining how consumers engage with their

The bedrock of personalized skincare is the orchestrate diverse skin traits. Armed with this genetic compass, cosmetic experts can curate formulations enriched with ingredients tailored to specific genetic profiles. Consider the case of individuals with genetic inclinations towards reduced collagen synthesis—these individuals might be steered towards collagen-boosting formulations, etching a narrative of skincare as

The intertwining of genetic information and cosmetics ushers forth a cluster of ethical questions demanding thoughtful exploration. The sanctity of data privacy, the principle of informed consent, and the ethical stewardship of genetic data stand tall as pillars guiding the integration of genetic profiling into cosmetics.

adherence to ethical tenets will pave the way for a symbiotic relationship between consumers

The embrace of genetic profiling within the cosmetics sphere carries a trove of potential benefits: heightened product efficacy, the

BECAUSE YOU'RE NOTHING LESS

NANO-REVOLUTION: ILLUMINATING THE PATH TO NEXT-GEN DISEASE TREATMENTS

For instance, researchers are developing nanoparticles that can selectively bind to cancer cells, delivering a concentrated dose of medication only where it's needed.

Solving the Puzzle of Drug Delivery

One of the biggest challenges in medicine has been delivering drugs to the right place at the right time. Nanoparticles are like tiny drug carriers, navigating through the intricate pathways of the body to reach their designated targets. These carriers can be tailored to respond to specific cues – such as changes in pH or the presence of certain molecules – ensuring that the drug is released exactly when and where it's

Personalized Medicine: One Size Does Not

No two individuals are the same, and this holds true at the molecular level.

Nanomedicine is making strides towards personalized medicine by utilizing a patient's genetic information to design nanoparticles that are tailor-made for their unique biology. This not only enhances the treatment's effectiveness but also reduces the risk of adverse reactions.

Beyond Pharmaceuticals: Diagnostic and Theranostic Nanoparticles

Nanomedicine isn't limited to drug delivery alone; it's expanding horizons in diagnostics too. Nanoparticles can be engineered to detect specific biomarkers, enabling early disease detection and precise monitoring of

In conclusion, the marriage of nanotechnology and medicine is ushering in a new era of healthcare. The days of one-size-fits-all treatments and debilitating side effects may soon be behind us, replaced by therapies that are as precise and individualized as the patients they serve. As nanomedicine strides confidently into the future, the prospect of conquering diseases that have long eluded us is no longer a distant dream but a tantalizing reality within reach.

GATEPOWER

THE RIGHT KIND OF ENERGY

FLUIDFORYOUR MOTION

SAYNOTOMEDIOCRITYANDGRASPYOURDAYBYTHEHORNSWITH HYDRAULICS.

SUGARANDADDITIVES-FREE,BRIMMINGWITHNOURISHING INGREDIENTS,HYDRAULICSISTHESCIENTIFICALLY-BACKED DRINKABLEDOMINATIONFORTHETHRILL-SEEKERSAND ALL-NIGHTERS,PARTYANIMALSANDGYMFREAKS.

CELEBRATEOURUNIFYINGDRIVETOPERFORMATOURMOST POWERFULANDACCENTUATEYOURADRENALINEWITHHYDRAULICS’ TERRIFIC-TASTINGTECTONICPOWER.

OUTRUNTHEREST.BETHEBEST.

BECAUSE YOU'RE NOTHING LESS

WWW.WEAREWONDERFUL.CO.UK

AMBINTERNATIONALestunesociété algérienneactivedansledomainedes complémentsalimentairesetproduits

Located in Rainham, Kent, Associated Veterinary Services is a Royal College of Veterinary Surgeons (RCVS) registered veterinary practice, specialising in the export health certification of products that are of animal origin and live animals. It provides veterinary Inspections of commodities for export, legal advice relating to export certifications, and technical support relating to import permits and export procedures. Furthermore, AVS also provide comprehensive education training which teaches exporters how to obtain highly valued import permits, and helps them discover new export opportunities. Led by its founder and owner, veterinary surgeon Doctor Veneta Kozhuharova (DVM, MRCVS, Cert. CFVHNut), AVS delivers its services nationwide.

The practice’s strong and versatile team consist of Animal and Plant Health Agency (APHA) approved and highly experienced veterinarians, alongside support certification officers. As a team, they have successfully certified thousands of consignments of products that are of animal origin, and animal by-products. Catering to individuals, and multinational organisations, AVS serves a vast array of industry sectors, including retail, food, pet food, leather, taxidermy, and laboratory and research institutions. The company focuses on delivering a high quality and reliable export service, customised to the client’s business needs where necessary. It has a multitude of experience working to extremely tight deadlines, and frequently accommodates clients that are in that type of scenario – displaying complete flexibility.

In November 2021, AVS introduced export certification of pet horses, race horses, and commercial exports such as zoo ungulates. In January 2022, AVS launched Small Animal Export Certifications, which will include pet travel and commercial exports, including zoo animals. By launching new services, AVS continues to develop its reputation as reliable organisation within the animal health industry. Its talented team have a breadth of expertise and knowledge, and works closely with businesses to simply the certification process."

Associated Veterinary Services Limited, 24A Longley Road, Cranford House, Rainham, Kent, ME8 7RU

T 07401983491

A BRAND YOU CAN TRUST

From ideation to bottling, every Wonderful product is created right here in the UK at our innovative facility.

Aligned with all national standards and safety regulations, Wonderful takes best practices seriously and pledges never to use any substandard ingredient or process. Your skin deserves that much!

www.WeAreWonderful.co.uk

About Newgate

We create and deliver quality products that enrich both inner and outer beauty – that is our mission. We believe that if you start with wellness and mindfulness, you can also achieve self-confidence and balance; the precursors to radiant beauty.

Our ethical, fair trade company believes in the old Latin saying, “Mens Sana in Corpore Sano,”“a healthy mind in a healthy body;” and we take a holistic approach towards helping you achieve this goal. Leading from this, Newgate’s products encompass a range of natural-based, efficient supplements, all manufactured, tested, and packaged in the UK.

www.newgate.org.uk info@newgate.org.uk

Newgate Labs Ltd.

HEAD OFFICE 71-75 Uxbridge Road London W5 5SL

United Kingdom

WAREHOUSE AND DISTRIBUTION 55 Lombard Rd London SW11 3RX

United Kingdom

Office: +44 (0) 207 228 6051 Mobile: +44 (0) 7493 203305