Tescan's FIB-SEM solutions for life sciences

Tescan’s world-class imaging technology delivers complete solutions for researchers in all branches of science. Due to the high versatility and customisable design of all Tescan systems, it is quite easy to design and manufacture dedicated instruments exactly suited to the customer’s needs.

The FIB-SEM encompasses ultrahigh-resolution imaging, variable pressure observations, 3D tomographic methods, and complex solutions including correlative light-electron microscopy or cryogenic techniques.

The Tescan Amber Cryo is an alternative solution to prepare cryo lamellae for your TEM and has the following features:

• Flexible cryo-FIB-SEM workstation for your most demanding applications under cryogenic conditions

• Optimised cryo-TEM lamella workflow for artefact-free planar on-grid lamella from plunge frozen specimens

• Compatible solution with all cryo-TEM on the market

• Excellent SEM imaging performance at very low-kV

• Cryo-user account with defined DrawBeam project dedicated for your cryo operations

• Easy navigation including extended field-of-view, two cameras, and 3D active collision model

• Easy-to-use, fully customisable, application-oriented, and modular user interface

• Attractive optional packages for various applications.

The Tescan Solaris is an advanced UHR FIB-SEM for 2D and 3D characterisation of your biological and beam-sensitive samples. This model’s key features are:

• UHR imaging of beam-sensitive samples at low-kV

• Routine investigation of heavy-metal stained resin-embedded samples with excellent contrast using the In-beam BSE detector at low-kV

• Best resolution Ga FIB column with optimised ion optics for excellent performance and reproducibility

• Site-specific TEM lamella preparation and in-situ visualisation with an easyto-use STEM detector that offers costeffective imaging results comparable to TEM

• 3D nano visualisation and volume reconstruction of resin-embedded cellular structures

• Cryo UHR SEM imaging and cryo-FIB- SEM applications.

Taken with the Tescan Solaris

Resin embedded mammalian cells. Additionally, an inverted image was acquired using In-Beam BSE detector at accelerating voltage 2.5keV

Resin embedded brain tissue. Cross-section was prepared with Ga FIB and visualised using In-Beam BSE detector

Taken with the Tescan Amber Cryo

Overview image of on-grid lamella inside the cell

Top view of a thin lamella prepared for subsequent cryo-TEM analysis

WIRSAM SCIENTIFIC

Tel: (011) 482 1060 marketing@wirsam.com www.wirsam.com