BIOTEK'S CYTATION RANGE OF INSTRUMENTS COMBINES MICROSCOPY WITH MULTI-MODE DETECTION

from Analytical Reporter July/ August 2021

New microscopy method reaches deeper into the living brain

BioTek’s Cytation range of instruments combines automated upright and inverted microscopy with conventional multi-mode microplate reading in a unique, patented design. The Cytation instruments are modular in design, allowing end-users to pick and choose modules to suit their laboratory requirements. Temperature control and shaking are standard. CO2/ O2 control; reagent injectors and Peltier cooling are available.

The Cytation 7 supports automated digital upright and inverted widefield microscopy. The inverted microscopy module provides sample visualisation from 1.25x to 60x magnification in fluorescence, brightfield and colour brightfield. The upright microscopy module, with reflected light imaging, enables even more applications such as ELISpot or fast slide scanning and ROI detection workflow. Multimode microplate reading utilises a monochromator-based detection module for fluorescence, UV-Vis absorbance and luminescence.

The Cytation 5 combines automated digital microscopy and conventional microplate detection in a configurable, upgradable platform. The microscopy module offers up to 60x magnification in fluorescence, brightfield, high contrast brightfield, colour brightfield and phase contrast. The multi-mode filter-based module detects fluorescence, fluorescence polarization, time-resolved fluorescence, TR-FRET, luminescence and filter luminescence. The monochromator-based module detects fluorescence, luminescence and UV-Vis absorbance detection. The Cytation 5 can be configured to detect Laser AlphaScreen / AlphaLISA.

The Cytation 1 includes fluorescence and high contrast brightfield imaging, with conventional multi-mode detection for filter/dichroic fluorescence, time-resolved fluorescence, fluorescence polarisation, luminescence, filtered luminescence and UV-Vis absorbance detection.