Pharmaceutical & Cosmetic Review Africa Q3 2021

Page 24

SKIN CARE

Combat ashy skin with moisturising essentials Dry skin irritancy is a universal struggle. Nearly every person will experience it at some point in life. Exogenous factors like the weather can have an effect, but luckily there are defenses that can be used to protect against dry skin as well as proactively counteract it. Jacques Strydom, technical manager at AECI Specialty Chemicals, discusses dry skin in various skin types and how to address it with essential moisturising actives.

W

INTER WITH ITS cold temperatures,

A SOLUTION TO IMPROVE DRY SKIN

EXPLORING HYALURONIC ACID

low humidity and chilling winds is

Besides the itchiness and irritancy caused by

Arguably one of the most important moisturising

normally the worst time of year for

dry skin, it also makes the skin appear older. Dry

actives is hyaluronic acid (HA). HA occurs naturally

skin moisture. These environmental factors are

skin does not necessarily cause cracks, but it

in all vertebrate tissues and throughout the body

rather effective at stripping the skin of its natural

does enhance the appearance thereof.

in various connective tissues, synovial joint fluids

The solution? Moisturisation, of course.

and in varying amounts in the skin. It is in the

would protect the skin from transepidermal water

Luckily, moisturisation is a well-studied field of

skin that the body holds the primary reservoir

loss (TEWL). Over and above the direct effects

skin care and one that we know to be absolutely

of HA – up to 50% of the total. Because of its

of the weather, when it is cold, we tend to take

vital to modern skin health. Today, there are many

unique rheological, viscoelastic and hygroscopic

warmer (and longer) showers or baths, once again

options to promote moisturisation, including

properties, HA plays a pivotal role in protecting,

stripping the skin’s lipid barrier with soap.

ingredient classes like emollients that form

stabilising and reinforcing skin at the cellular level.

lipid barrier, which under normal circumstances

Apart from a beautiful appearance, higher

an artificial barrier to prevent moisture loss,

HA, along with collagen, elastin and essential

levels of melanin protect skin during sun

humectants that draw moisture to the skin and

lipids, form the primary elements of the human

exposure. While there are many benefits to having

which hydrate the stratum corneum, as well as

skin matrix. Native HA is naturally produced by

a more melanated skin type, there are also certain

actives that penetrate deeper into the skin to

skin cells mainly in varying concentrations of low

drawbacks. Differences in melanin levels in turn

restore and protect important mechanisms that

molecular weight polymers (15kDa), all the way

relate to differences in sun-related skin changes,

keep skin supple and hydrated.

through to high molecular weight polymers (up

affecting the stratum corneum’s water content

to 2 000kDa). The size of the polymer dictates its

and its ability to retain moisture. Dry skin is also a

biological role in the skin and its primary benefit.

bit more noticeable on certain skin tones, due to the direct contrast with the lighter appearance of dry and flaky skin cells.

When using HA in skin care, scientists prefer to work with sodium hyaluronate (or NaHA), which is the synthesised salt counterpart of HA. It has similar benefits to HA and is

7

more stable in its form and less likely

SIGNS OF DRY SKIN:

1. roughness 2. reduced firmness 3. cracking 4. flaking 5. scaling 6. reduced elasticity 7. ashy skin/white lines.

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QUARTER 3 2021 // P&C AFRICA

to oxidise. Sodium hyaluronate also has a smaller molecular size, so it can penetrate deeper into the skin, where it can attract and hold moisture, swell and therefore assist in making skin look plumper. This mechanism of action results in a youngerlooking skin with less visible wrinkles.


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