Pharmaceutical & Cosmetic Review January 2020 by New Media B2B

JANUARY 2020 | Volume 47 | Number 1

www.pharmacos.co.za

Working together to make

sustainability beautiful The ultimate SPECIALITY INGREDIENTS issue

NEW: 2020 Packaging Profiles

SCIENTIFIC EQUIPMENT to meet your laboratory needs

Learn how to lead and succeed in the competitive world of beauty

Join us for the P&C REVIEW 2020

Beauty Benchmarks & Innovation TH I NK TANK

The P&C Review industry conference will be back next year with an unmissable programme, featuring leaders, innovators and forward thinking industry experts. See how your brand stacks up against some of the most sustainable ones, meet beauty vloggers and bloggers and get inspired to create great social media content while you learn about how to adapt to rapid changes in the market. Our presenters will educate and enlighten you on claims, social media and influencer marketing, INCI listing dos and don’ts, financial wellness, bricks versus clicks and the rise of e-commerce, sustainability, global trends, market data and category insights.

SOUTH AFRICAN PHARMACEUTICAL & COSMETIC REVIEW Date:

Thursday, 20 February 2020

Time:

08h30 to 16h00

Venue:

Media Park Auditorium, Auckland Park, Johannesburg, South Africa

• Book your seats today for R1 495 per person including VAT • You will receive a full breakdown of the day once you have booked and paid for your ticket as well as a breakdown of all the speakers. • To register, send an e-mail to Abby.Vorster@newmedia.co.za with the names and surnames of your conference delegates.

Contents SOUTH AFRICAN PHARMACEUTICAL & COSMETIC REVIEW

January 2020 | Volume 47 | Number 1

w w w.pharmacos.co. za

6 NEWS

SIN List to set a new standard for sustainable chemicals

New app to identify glass bottle non-compliance

Advancements in micro protection from Symrise

A modern take on historical biological resources

10 PRODUCT NEWS

What’s New in South Africa

11 INDUSTRY TALK

A route to uniting researchers and holders of traditional knowledge

12 EVENTS

Book your seat for the P&C Review 2020 conference

Interpack announces new digital show tools

Highlights from the 2019 Goldpack Awards

18 PACKAGING PROFILES

Designa introduces new plastic squeeze tubes

Rotolabel pushes boundaries in sustainability

32 PHARMA FOCUS: LAB EQUIPMENT & SERVICES

Scientific instruments from Labotec

Analyse, identify and verify in a flash

Aspen turns to Veolia for new water purification technology

40 CLEANROOM TECHNOLOGY & CONTROL

Sterilisation solutions from Telstar

Harmonisation in disinfectant efficacy testing

A guide to validating high purity water systems

22 SPECIALITY INGREDIENTS

Chemyunion introduces Agen for healthier skin

Kolabtree reveals trends in sustainable cosmetics

Danlink Ingredients diversifies into personal care

Rainbow algae extract promotes luminous skin

Botanica’s modern approach to historical biological resources

Responsible products become a key focus for BASF

Pure solutions for natural beauty products 44 COLOUR COSMETICS

An evolution in modular water treatment

Create the perfect look with Merck

Pure solutions for natural beauty products

48 ASSOCIATION NEWS

The latest developments from Coschem and SAAFFI

P C Review | JANUARY 2020 |

SOUTH AFRICAN PHARMACEUTICAL & COSMETIC REVIEW

From the editor

THE TEAM EDITORIAL

Editor: Abby Vorster +27 (0)11 877 6038 abby.vorster@newmedia.co.za Layout & Design: Andipha Nkoloti Contributors: Dr Chamunorwa Togo, Karen Maier, Kenneth Amaral, Ramya Sriram ADVERTISING Sales Executive: Carla Melless +27 (0)83 260 6060 carla.melless@newmedia.co.za

Passionate about plant-based

Sales Executive: Anita Raath +27 (0)82 976 6541 anita.raath@newmedia.co.za Sales Executive: Candida Giambo-Kruger +27 (0)71 438 1918 candida.giambo-kruger@newmedia.co.za INTERNATIONAL SALES

’m so excited about the new year and our

help research and development teams

January edition of P C Review. We have a

realise their vision, while the cleanroom

bumper feature on speciality ingredients

technology and control feature on page

on page 22 with the majority of articles

40 takes a look at sterilisation solutions,

highly focused on natural, sustainable and

disinfectant efficacy testing and validation

plant-based ingredients. It’s interesting

methods for high purity water systems.

Germany/Austria/Switzerland: Eisenacher Medien Erhardt Eisenacher +49 228 249 9860 info@eisenacher-medien.de Italy: Ngcombroker Giacomo Rotunno +39 370 101 4694 g.rotunno@ngcombroker.com

very much in line with Veganuary, which

makeup, don’t miss out on our exciting

Taiwan: Ringier Trade Media Sydney Lai +886 4 2329 7318 sydneylai@ringier.com.hk

started in the UK and has also taken off in

feature on colour cosmetics, on page

CIRCULATION

South Africa. Every January, people all over

44. Inspirational trends from Merck and

the world start the new year with a plant-

Sensient’s pure solutions for natural beauty

Circulation Manager: Felicity Garbers felicity.garbers@newmedia.co.za

based diet for a month or more – hence the

products are highlighted this month.

to note how the growth of this feature is

campaign name. A report revealed that in 2019, South

If you’re into the business of beauty and

Remember to book your seat for our conference on 20 February. The P C

PUBLISHING TEAM General Manager: Dev Naidoo Production Controller: Mandy Ackerman

Africa was among the top six countries most

Review Beauty Benchmarks & Innovation

Art Director: David Kyslinger

enthusiastic about Veganuary, which I’m

Think Tank takes place at Media Park in

JOHANNESBURG OFFICE

sure will have a trickle-down effect on the

Johannesburg. Please send me an email for

beauty industry. I’m even giving Veganuary

more information on the programme or to

a go with both my husband and I having

book seats.

New Media Publishing, Ground floor, Media Park, 69 Kingsway Avenue, Auckland Park, 2092 Tel: +27 (0)11 877 6111, Fax: +27 (0)11 877 6198 POSTAL ADDRESS PO Box 784698, Sandton, Johannesburg, 2146

switched to a plant-based diet. What else can you look forward to this month? We’ve launched a new feature –

The P C Review team and I wish all our readers and advertisers everything of the best for 2020.

MANAGEMENT TEAM

packaging profiles – and have two leading suppliers included in this edition. Both

Published by New Media, a division of Media24 (PTY) Ltd

MANAGING DIRECTOR: Aileen Lamb

Enjoy the read.

Designa and Rotolabel share their latest

COMMERCIAL DIRECTOR: Maria Tiganis

developments and new products on pages

BRAND STRATEGY DIRECTOR: Andrew Nunneley

18 and 20 respectively.

CHIEF FINANCIAL OFFICER: Venette Malone

We have two interesting sections

HEAD OF HR: Camillah West

dedicated to the needs of our readers from

CEO: MEDIA24: Ishmet Davidson

the pharmaceutical industry. Our pharma focus on page 32 showcases scientific

HEAD OFFICE

instruments and laboratory equipment to

New Media House, 19 Bree Street, Cape Town 8001 Tel: +27 (0)21 417 1111, Fax: +27 (0)21 417 1112 Email: newmedia@newmedia.co.za PO Box 440, Green Point, Cape Town 8051

EDITORIAL ADVISORY BOARD Past-President, Society of Cosmetic Chemists SA

Prof Dr Aubrey Parsons

John Knowlton

CEO of the Generic and Biosimilar Medicines of Southern Africa

Professor Emeritus, Faculty of Health Sciences, Nelson Mandela University

Vivian Frittelli

Prof N T (Raj) Naidoo

P C Review is the official journal of: CTFA - The Cosmetic, Toiletry & Frangrance Association of South Africa GBM - Generic and Biosimilar Medicines of Southern Africa

4 | JANUARY

Consultant, Cosmetic Solutions

2020 | P C Review

COSCHEM - The Society of Cosmetic Chemists of South Africa HPA - The Health Products Association of Southern Africa AMA - The Aerosol Manufacturers’ Association of South Africa

Pharmaceutical Cosmetic Review is published by New Media 11 times a year and circulates to manufacturers, packers and distributors of pharmaceuticals, health products, cosmetics, detergents, soaps, toiletries and allied products. The journal is an up-to-date source of reference for company directors, factory and production managers, marketing executives, engineers, import agents, buyers and research personnel. While precautions have been taken to ensure the accuracy of its contents and information given to readers, neither the editor, publisher, or its agents can accept responsibility for damages or injury which may arise therefrom. All rights reserved. © Pharmaceutical Cosmetic Review. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, photocopying, electronic, mechanical or otherwise without the prior written permission of the copyright owners. Pharmaceutical Cosmetic Review is printed and bound by CTP Printers - Cape Town. Copyright: all rights reserved. ISSN 0257-8719

Launched a new product in 2019/20

Make a

Statement about it 2020

New Product Competition

ENTRIES NOW OPEN C o n t a c t A b b y V o r s t e r : A b b y .V o r s t e r @ n e w m e d i a . c o . z a | + 2 7 ( 0 )11 8 7 7 6 0 3 8

NEWS

Eco-friendly solutions for the personal care market CONSUMERS ARE LOOKING for personal care ingredients that are ecologically sourced, conserve resources or help to avoid negative environmental or social impact. At SCS Formulate on 12 and 13 November, BASF presented its latest solutions with a focus on natural actives. The chaga mushroom is a superfood renowned for various health benefits and has both traditional and modern uses. Inolixir is a hyper-concentrated bioactive ingredient, benefitting from all the nutrients and properties of the chaga mushroom thanks to an innovative and eco-friendly subcritical water extraction (SWE) technology. Instead of organic solvents, this method uses pressurised water heated to between 100°C and 374°C for extraction. Inolixir produces quick and long-lasting results for tired and sensitive skin.

‘With our new bioactive ingredients and biodegradable solutions, we support our customers in developing innovative products that meet the needs and expectations of today’s environmentally conscious consumers – as the demand for sustainably sourced products helping to protect and beautify skin and hair increases steadily,’ said Dirk Mampe, vice president, business management, BASF Personal Care Solutions Europe. Consumers are progressively concerned about the potential impact sunscreens may have on the environment and eco-friendly sunscreens are in high demand. BASF’s EcoSun Pass is a methodology that enables the environmental impact evaluation of UV filter systems. The environmental impact assessment system developed by BASF is clear, transparent and comprehensive.

Local health initiative granted USAID funding for expansion A NATIONAL DEPARTMENT of Health initiative is providing access to chronic medications for South Africans who are dependent on the public sector. Cipla Foundation will help to expand the Central Chronic Medicines Dispensing and Distribution (CCMDD) programme through funding from the United States Agency for International Development (USAID). While the programme is already well established in South Africa, with about 1.9 million patients enrolled, this partnership with USAID will grow the Cipla Foundation CCMDD network of five units to 50 over the next two years. This expansion is already underway with deployment of the first four units. Having

perfected the model over the past 12 months in KwaZulu-Natal, things are moving swiftly. With USAID’s support, the Cipla Foundation recently landed four units in Johannesburg, in the greater Tembisa area (Ivory Park and Rabie Ridge). Following the rollout of the first units in the City of Johannesburg, which became operational at the end of the year, the next units will be deployed in Soweto and Orange Farm. This means that more patients with chronic illnesses across the country will have easier access to life-saving medication. ‘This is in line with Cipla’s purpose of Caring for Life. Through our primary healthcare initiative, Sha’p Left, the CCMDD initiative came as a natural expansion in providing access not to the few, but to the many. By ensuring convenience and access for patients, these facilities can improve patient adherence to chronic medication, while simultaneously reducing patient load and congestion at national health facilities,’ says Paul Miller, CEO of Cipla South Africa, a parent body of the Cipla Foundation. The Cipla Foundation Project will work closely with the Department of Health and other stakeholders to optimise enrolment into the CCMDD programme and maximise patient retention in the programme.

Paul Miller, Cipla South Africa CEO

6 | JANUARY

2020 | P C Review

Perfluorinated chemicals used in dental floss are among the chemicals pinpointed on ChemSec’s SIN List

SIN List aims to set a new standard for sustainable chemicals CHEMICAL SPECIALIST ORGANISATION, ChemSec reveals the latest additions of industrial chemicals on its so-called SIN List – a compilation of over 900 toxic chemicals that should be avoided in the global supply chain. Followed by many brands, chemical producers and manufacturers – as well as the Dow Jones Sustainability Index, UNEP and other influential bodies – the latest additions are expected to set a new standard for sustainable chemicals management. Perfluorinated chemicals, or PFAS, used in dental floss, cooking pans, food packaging and water-resistant clothes are among the chemicals pinpointed. Currently there are several thousand different PFAS in use worldwide. Many of them belong to a newly recognised category of chemicals identified as persistent, mobile and toxic chemicals (PMTs). Due to their specific properties and heavy industrial use, these substances are now widespread in global ground- and drinking water. ‘These chemicals have managed to escape regulation as they do not exactly match current legal criteria. The most well-known chemicals in this category are the fluorinated compounds, often called “forever chemicals” since they do not break down in nature. Even though the debate is ongoing on exactly how to regulate these substances, smart manufacturers should already begin to phase them out,’ says Dr Anna Lennquist, project manager for the SIN List at ChemSec. Nanomaterials have also made it onto the SINList. Engineered nanoforms are legally covered by REACH, but so far, the focus has been on establishing definitions for registration requirements. Meanwhile, brands and manufacturers have been uncertain on how to approach hazard management of nanomaterials. The SIN List now includes carbon nanotubes, one of the more well-studied nanomaterials. First engineered in the ’90s, they are used to make durable, lightweight materials, for electrical conductivity, as a super black pigment and for water purification. ‘Until now, the debate about the safety of nano has focused on the need for more research. However, this is a perfect example of where there is enough science to say that these materials should not be used,’ Dr Lennquist concludes.

NEWS

Evonik thrives despite ongoing global economic issues THE GLOBAL PRODUCER of ingredients is sticking to its full-year earnings outlook despite global economic challenges. Evonik expects adjusted EBITDA to remain at least stable compared to last year. Sales are now expected to be slightly lower than the previous year because of lower demand. But Evonik had expected sales to remain stable. Excluding the divested methacrylates business, in 2018 the company generated sales of €13.3 billion and adjusted EBITDA of €2.15 billion. ‘We prepared ourselves at an early stage with stricter cost discipline and additional contingency measures for a cooling global economy,’ says Christian Kullmann, chairman of Evonik’s executive board. ‘We are being very proactive to

ensure we meet our full-year outlook.’ The 2018 initiated efficiency program to reduce administrative and selling expenses by €200 million annually has been accelerated. By end of this year, Evonik will achieve saving of €120 million, €20 million more than originally planned. A further €20 million will be saved with additional contingency measures such as delaying new hires and more restrictive expenditure on external services. The global economic slowdown continued to impact Evonik’s performance in the third quarter. From July to September, sales fell three percent to €3.23 billion due to lower volumes and selling prices. Adjusted EBITDA fell six percent year on year to €543 million. In its Nutrition & Care segment sales

declined two percent to €1.14 billion in the third quarter and performance materials sales decreased 20 percent in the third quarter to €475 million, compared to the same quarter in the previous year.

App to identify glass bottle non-compliance A COLLABORATIVE PROJECT between SGD Pharma’s quality and marketing departments, the new SDG Pharma App makes it possible to identify non-compliances in moulded pharma glass bottles, which may be discovered by customers

during an incoming or online inspection. It also demonstrates the company’s transparency in working with customers towards a mutual objective of safeguarding patients. The SGD Pharma App aims to optimise and harmonise exchanges between quality controllers and technical staff. A screen shot of the new ‘This project was initiated SDG Pharma app listed on in response to customers’ the App Store increasing demand for glass non-conformities training. It is crucial for them to be able to identify and recognise non-conformities quickly in order to improve inspection processes and make the right decision,’ says Quentin Ritter, quality project manager at SGD Pharma. Available for free from the Apple and Google Play stores, it only takes a few clicks for users to

install the app, create an account and receive unlimited access to a 2D visual compilation of the most frequently encountered forms of non-compliance. Users can refine their searches by administration method (parenteral, oral or nasal), by location or non-compliance types corresponding to various effects on patients or on filling lines, such as critical, major or cosmetic. Once a non-compliance has been identified, the user then accesses a dedicated page with a visual example and a written definition of the type of non-compliance and its associated acceptable quality level (AQL) in conjunction with ISO 2859-1. ‘The mission of SGD Pharma is to improve safety for the end user. The SGD Pharma App meets hospital staff’s growing demand for zero tolerance, including cosmetic quality. With this app, open to all professionals in the industry and designed with customers in mind, the company aims to support the global pharma industry in protecting patient health,’ says Emmanuel Lepitre, head of development and quality at SDG Pharma.

P C Review | JANUARY 2020 | 7

NEWS

The access versus treatment improvement predicament of personalised medicines TARGETED THERAPIES LIKE personalised medicine use a proactive approach, increase patient stratification and targeting, and aim to improve outcomes for healthcare players, according to GlobalData, a leading data and analytics company. Its latest thematic report, The State of Personalised/Precision Medicine suggests the key benefit of personalised and precision medicines is improved selection of an optimal treatment path, benefitting both patients and payers, as potentially ineffective medicines will be less likely to see use in specific patient pools. Michael Breen, associate director at GlobalData, comments: ‘When a disease has different patient segments, it’s possible that not all will respond to a particular medicine the same way, if at all. By identifying patient subgroups through biomarker analysis, personalised medicine will help identify which groups may benefit from a given treatment. This helps the patient get the most appropriate treatment more quickly, saving money for the payer since they are less likely to reimburse ineffective therapeutics.’

8 | JANUARY

2020 | P C Review

The majority of attention for personalised medicine has been in oncology, but there is an unmet need for expansion to other indications. Fern Barkalow, senior director at GlobalData reports: ‘While oncology has led the way in terms of precision medicine development, these therapies are positioned to fulfil unmet needs in other therapeutic areas. Approximately 90 percent of the top-marketed precision medicine therapies in 2018 were approved for oncology indications, and these can serve as a roadmap for development of precision medicine drugs in other therapeutic areas. The report highlights a variety of case studies in oncology that should be useful to many stakeholders pursuing this approach.’ Development costs associated with personalised therapies are expected to be higher than average, partially due to the highly specific nature of these agents, coupled with the need for a companion diagnostic. Accordingly, experts report market access hurdles will be the greatest challenge in the development and launch of these therapies.

Advancements in modern micro protection with SymDeo B125 SYMRISE INTRODUCED SYMDEO B125 10 years ago as an effective and readily biodegradable deodorant active used to prevent body malodours. It’s typically used in underarm cosmetics and has been proven effective in foot care formulations. The company’s researchers have now been able to show this deodorant active is microbiome-friendly and does not disrupt the sensitive underarm biota. Symrise’s findings regarding the influence of deo actives on the human axillary microbiome are the first in the industry. This underlines its pioneering position in the field of modern micro protection. ‘Globally, we are observing a growing interest in exploring the impact of personal care products on healthy skin,’ says Dr Florian Genrich, senior global product manager: micro protection, Symrise cosmetic ingredients division. ‘Consequently, cosmetics manufacturers are facing continuously increasing expectations from the consumer side, which requires the industry to keep up with state of the art technologies. As a manufacturer of cosmetics ingredients, we continuously conduct intensive research on our ingredients and explore new methods, such as in the field of skin microbiome analysis. We are proud to deliver additional benefits to our customers within our existing and versatile product portfolio,’ Dr Genrich concludes.

2020

ood f

SOUTH AFRICAN PHARMACEUTICAL & COSMETIC REVIEW

February

SOUTH AFRICAN

Professional Beauty GCC 16 to 17 February Festival Arena, Dubai, UAE www.professionalbeauty.ae

2020 SUBSCRIPTION FORM

P&C Review Annual Conference

20 February Media Park, Auckland Park, Johannesburg www.pharmacos.co.za

March

CosmoPack + Cosmo Perfumery & Cosmetics 12 to 15 March Bologna, Italy Fair District www.cosmoprof.com/cosmopack

Cosmo Hair, Nail & Beauty Salon

13 to 16 March Bologna, Italy Fair District www.cosmoprof.com

Propak East Africa

17 to 19 March KICC, Nairobi, Kenya www.propakeastafrica.com

SAAFFI Seminar

19 March Altron (Bytes) Conference Centre, Midrand, Gauteng www.saaffi.co.za

in-cosmetics Global

April Luxe Pack

Please complete in block letters, select your subscription option, and return this form, along with your payment to: NEW MEDIA, a division of Media24 (Pty) Ltd, PO Box 440, Green Point, Cape Town 8051 Email: felicity.garbers@newmedia.co.za

SUBSCRIPTION OPTIONS (please tick) 1 YEAR Food Review Pharmaceutical

Cosmetic Review

Food Review + Pharmaceutical

Cosmetic Review

2 YEAR

R588

R905

R588 R1066

R905 R1620

Full Name:........................................................................................... Designation: ........................................................................................ Company: ........................................................................................... Postal Address:................................................................................... .................................................................Code:................................. Country: .............................................................................................. Tel: (

)....................................... Fax: (

) ..................................

E-mail:................................................................................................. Main activity of company:................................................................... Approximate number of employees: .................................................. VAT No: ............................................................................................... ❑ I would like to receive the newsletters and feature announcements via email and may be added to the mailing lists. Signature:............................................................................................

Please select your preferred method of payment:

❑

31 March to 2 April Barcelona, Spain www.in-cosmetics.com

Direct Deposit (Complete and email this form to: felicity.garbers@newmedia.co.za

Payee:

Bank:

Acc No:

New Media Publishing (Pty) Ltd .

Nedbank Seapoint

1069321540

Branch Code: 10-69-09-00

❑

Credit Card (Mastercard & Visa only) Name of card: .............................................................................

8 to 9 April Shanghai Exhibition Centre, China www.luxepackshanghai.com

Expiry Date: ................................................................................ Card Number: ............................................................................. CVC Number............................................................................... Date: ...........................................................................................

Natural & Organic Products Europe

19 to 20 April ExCel, London, UK www.naturalproducts.co.uk

RE V IE W

WHAT'S ON IN

DIARY

Signature:....................................................................................

❑

TAX INVOICE REQUIRED Note: The above prices are applicable to South Africa only. International rates available on request.

P C Review | JANUARY 2020 |

STREET

1 Quality you can trust Proudly South African skin care and cosmetics brand, Bramley has re-launched with a new look, redesigned logo and new product developments. Clean, simple and elegant, the solid oval shape of the logo has been maintained to reflect stability and cohesiveness, while a new modern font has been used. The brand has also extended its product offering in the Lavender range and welcomed the limited-edition Be Happy and Be Real

Body Spritzers to its Be You range.

2 Put your feet first Matsimela’s new at-home foot care range is formulated with key ingredients to hydrate, exfoliate and protect the

skin from harmful environmental elements. It includes a foot mask spray, formulated with Glycolic Acid to aid intensive exfoliation of the heels and an intensely moisturising heel balm, which is formulated with Urea, Glycerin, Peppermint Essential Oil and Shea Butter.

3 Back to beat heartburn Gelusil Plus, an antacid indicated for the relief of heartburn during pregnancy, has been re-launched in South Africa. Nova Pharmaceuticals has added Gelusil Plus to its prenatal portfolio, which includes the number one prenatal supplement in the country, Pregomega Plus. Gelusil Plus is available in a 200mℓ suspension at leading pharmacies nationwide.

4 Superior CBD infusions Oil Science has launched a range of premium, 100 percent natural and vegan-friendly certified CBD oil products, formulated to improve physical and mental well-being. The range includes CBD oil drops and an anti-inflammatory serum, cream and gel – all infused with CBD. The products are packed in 30mℓ bottles with a medical dropper, giving

approximately 600 drops per bottle. Available in 300mg (low strength) in natural and cinnamon flavour, and 1 000mg (high strength) in natural flavour, the CBD oil products are completely THC-free with no psychoactive effects.

5 Vitamin D on the go NRF CalMag Fizzy with added vitamin D is a lime flavoured effervescent tablet that is easily absorbed by the body. One tablet daily, dissolved in a glass of water, allows for fast and gentle absorption and is suitable for the most sensitive digestive system. The product contains Vitamin D, which helps with the absorption of calcium, and Magnesium, to support the improvement of bone mass and assists in maintaining bone density.

| JANUARY 2020 | P C Review

INDUSTRY TALK

A route to uniting researchers and traditional knowledge holders There is a wealth of indigenous knowledge in Africa, which, coupled with best practices and products, can address various health challenges. Dr Chamunorwa Togo of the BioPark@Gauteng highlights standardisation as key to exploiting indigenous knowledge in the pharma and cosmetics industries.

hen one visits rural

dean at the Tshwane University of

world. It hopes to pinpoint more sources

communities and villages,

Technology’s Faculty of Science.

of indigenous knowledge and package

you’ll find practitioners with excellent solutions

By collaborating with traditional healers who use a plant derived remedy to assist

them for global consumption. It is currently providing entrepreneurial

for everyday ailments, yet we’ve not

individuals with bone and cartilage

support and interfacing with citizen

managed to commercialise and scale up

ailments, Prof Motaung has proven the

scientists, entrepreneurs and university

these solutions, to bring them to market.

traditional remedy holds bone cartilage

researchers to promote the exchange of

The BioPark@Gauteng, a business

regenerative properties. Not only has the

knowledge and wisdom. However, there is

incubator at The Innovation Hub, is

remedy offered an alternative treatment

a need to understand the complex system

working with traditional knowledge holders

solution to individuals lacking access to

of intellectual property and how to protect

and researchers to bring both parties

conventional medicine, it’s also inspired

it along with the business models of these

together. Its main aim is to harmonise and

Prof Motaung to launch a complementary

citizen scientists, to facilitate conversations

standardise the centuries old information

health product, La-Africa Soother.

and product standardisation.

to address safety issues and guarantee quality standards.

Knowledge brought to life Instead of subjugating and rejecting

The wealth of indigenous knowledge can

A humble approach focused on

also be seen in various cosmetics and beauty

recognising the efforts of traditional

products on the market, including Portia M

practitioners is paramount to address

Skin Solutions, Phepisa, Dermacell, K-squared.

some of challenges faced by humankind.

Nutraceutical brands harnessing the

This should be complemented by

indigenous knowledge as witchcraft, we

benefits of indigenous knowledge include

building confidence in the industry and

should embrace and harness its value.

Dikgabane consulting and Lefakong, while

not waiting for someone else to endorse

One valuable example is the work of

the beverage product, Royal Mabundu

our work. Opening up training systems

and condiments from Makhamisa Foods,

and allowing for the integration of

are also based on indigenous knowledge.

different ways of knowledge generation

DID YOU KNOW?

Professor Shirley Motaung, a biomedical

scientist The BioPark@Gauteng provides business development and the support to start-ups in the fields assistant of biopharmaceuticals, medical devices and diagnostics, indigenous knowledge-based nutraceuticals, cosmeceuticals and cosmetics. The support is provided in collaboration with Gauteng Department of Agriculture and Rural Development and eGoliBio Life Sciences Incubator.

can go a long way in harnessing

Moving in the right direction

traditional knowledge. Without taking

The BioPark@Gauteng is determined to

bold steps in the right direction, we may

take Africa’s indigenous knowledge to the

run the risk of remaining the proverbial hunter who kept looking for a kudu hidden in water while he was holding the horns and drinking from the same pond. •

ABOUT THE AUTHOR Dr Chamunorwa Togo is the general manager for bio economy at The Innovation Hub. He has extensive research experience and a strong background in biotechnology and general life sciences. Some of his areas of interest include bridging the gap between the laboratory and market, and the commercialisation of indigenous knowledge-based products.

The Innovation Hub – www.theinnovationhub.com

P C Review | JANUARY 2020 | 11

EVENTS

Book your seat at our beauty industry conference Following the highly successful P&C Review Beauty Business & Partners Conference in 2019, our industry event will be back in 2020. Join us in Johannesburg on 20 February, where we’ll have exceptional, relevant thought leadership content on offer from seven leaders in their respective fields.

Joint managing director of Extrupet, Chandru Wadhwani

Rob Maclean of eCommerce Experts

Samantha Fletcher, partner and client service director at G&G Digital

L’Oréal South Africa’s scientific and regulatory affairs advisor, Percy Sibanda

Raymond Chimhandamba, founder and director of Handas Consulting

earn how to lead and succeed in

managing director of Extrupet, Chandru

presentation on distribution channels,

the competitive world of beauty

Wadhwani will discuss global trends and

mobile tech trends and how cosmetics

at the P&C Review 2020 Beauty

the sustainability measures that can be

and beauty brands can utilise these to

Benchmarks & Innovation Think

applied locally. He will also delve into how

capture new markets in Africa.

Tank. Our beauty industry event will

to develop and maintain a sustainable

feature an unmissable programme

brand and provide insight into the local

regulatory affairs advisor, Percy Sibanda

of innovators and industry experts to

resources available for implementing

is back on the speaker line up for the

educate and enlighten delegates on

recyclable packaging.

2020 conference. Percy will lead a much-

claims, social media and influencer

Rob Maclean of eCommerce Experts,

L’Oréal South Africa’s scientific and

needed discussion on how to keep

marketing. The programme will also focus

the official Shopify experts, will weigh up

your claims in check while leveraging

on INCI listing dos and don’ts, financial

the pros and cons of e-commerce and

your product’s formulation ingredients

wellness, bricks versus clicks and the

how to build and launch user-friendly,

for success. He will also help attendees

rise of e-commerce, sustainability, and

engaging and successful Shopify sites.

understand the intricacies associated

beauty and personal care market data

Maclean and his team have built over

with cruelty free and natural and organic

and category insights.

80 eCommerce websites for local and

claims and how to structure and declare

international customers, including many

ingredients correctly on an INCI list.

See how your brand stacks up against some of the most sustainable ones, meet

in the beauty and cosmetics industry.

beauty vloggers and bloggers and get

Digital marketing and consumer insights

content while you learn about how to

Exploring Africa and compliant claims

adapt to rapid changes in the market.

Sharing his vast experience in launching

Innovation Think Tank will also feature

The conference takes place at the

and developing FMCG brands in African

a focused slot on financial wellness for

Media Park Auditorium in Auckland Park,

markets, Raymond Chimhandamba,

entrepreneurs and small businesses

Johannesburg. To book your seat for R1

founder and director of Handas

and a presentation on market data and

495 per person including VAT, send an

Consulting, will share a high-level

consumer insights.

inspired to create great social media

email to abby.vorster@newmedia.co.za. The event will also include a select group of exhibitors, which will showcase their products and solutions for the beauty, hair care, cosmetics and personal care industry.

Sustainability and e-commerce To encourage sustainability in the South African beauty industry, joint

12 | JANUARY

2020 | P C Review

The event will also include a select group of exhibitors, which will showcase their products and solutions

The P&C Review Beauty Benchmarks &

Samantha Fletcher, partner and client service director at G&G Digital, will present an unmissable session on digital marketing. G&G Digital is an independent digital agency with a passion for quality, smart creative solutions and sound strategies founded on deep insights. Samantha will bring her strong influencer connections to the conference to enlighten delegates on digital marketing. •

EVENTS

New digital tools announced in preparation for interpack

interpack

PROCESSING & PACKAGING

2019-11-26 interpack 2020_Südafrika_Kosmetikindustrie_88_5 x 262 + 3mm _SA Pharmaceutical & Cosmetic Review_4c_8481

According to the organisers, the 2020 edition of the processing and packaging show, interpack, is fully booked. Around 3 000 exhibitors from approximately 60 countries will present their solutions during the show, taking place from 7 to 13 May. ffective immediately, interested parties can access the exhibitors and products section on the interpack website, www.interpack.com to obtain an overview of this unique offer and the participating companies.

The branch search section provides eight target group icons for fast access. Users can click on the icons for a list of exhibitors that have corresponding products in their portfolio for the respective branch. Using the MyOrganizer function, various selection options allow future visitors to further refine their results and save them in a personal account. Users can select individual exhibitors as favourites and add notes, as well as synchronise the list with the interpack app, which is available for iOS and Android devices. The function also offers a personalised version of the trade fair layout, making it much easier to find your way around the 18 trade fair halls.

Life without Packaging conference Sustainability has been shaping the packaging industry for years and recently became a hotly debated issue as a result of the discussion around plastic packaging in particular. The new Life without Packaging conference will highlight the areas of packaging, sustainability and the environment by presenting different perspectives. Critics and advocates will be given an opportunity to have their say, discussing the necessities and what to avoid. The conference, taking place on 12 May, will focus on sustainability and environmental impact, as well as hygiene and the reduction of food waste. Details on the speakers and the conference programme are available on the interpack website.

Matchmaking with AI Another highlight among the new, digital offering is the revised Matchmaking tool to efficiently plan visits to the trade fair. Launched in November, the tool enables users to set up meetings prior to the show. Over time, the system learns from its interactions with the user and suggests potential contacts. These contacts can then be assessed, either positively or negatively, by swiping left or right in the app. The user’s decisions continuously improve suggestions. • Visit www.interpack.com for more information and to start planning your visit to the expo.

Southern African-German Chamber of Commerce and Industry 47 Oxford Road _ Forest Town 2193 JOHANNESBURG P.O. Box 87078 _ Houghton 2041 Tel. +27 (0)11 486 2775 _ Fax +27 (0)86 685 3729 tradefairs@germanchamber.co.za _ www.germanchamber.co.za

P C Review | JANUARY 2020 |

2019-11-26 interpack 2020_Südafrika_Kosmetikindustrie_88_5 x 262 + 3mm _SA Pharmaceutical & Cosmetic Review_4c_8481.indd 21.08.19 13:26

EVENTS

Awards promote packaging innovation & excellence

Since its inception in 1973, the Gold Pack Awards has grown in prestige. Today, it’s recognised as the South African showcase for the packaging industry. The gala dinner for the 2019 awards took place on 30 October at the Inanda Club in Sandton. P&C Review was there to celebrate with the winners.

lthough innovation is an

of creative design, marketing or

support has been received from Berry

appealing reason for

technology applied to packaging.

Astrapak, Polyoak and the Glass

awarding gold medals,

‘This may or may not include unique

Recycling Company.

it’s primarily excellence

or innovative ideas and technology,

in packaging execution that creates

but certainly results in entries that

medal winners. The various categories

demonstrate packaging

are divided into two broad groups.

excellence,’ he comments.

The first group relates to the product’s

The Gold Pack Awards

market type – from beverages and

event continues to

food to industrial, beauty, pharma and

be the highlight

household goods as well as packaging

of the packaging

components, processes and systems. The

industry’s calendar

second is defined by the materials used,

and receives

such as metals, glass, paper, rigid and

considerable

flexible plastics.

support, in the form

Criteria in the two groups are quite

of entries and financial

Home and personal care packaging awards

DID YOU KNOW? Up to 80 percent of the waste

In the category, Health, Beauty, Medical and Pharmaceutical

Packaging, Vaseline in Africa is recyclable and yet only four percent is recycled. Blue Seal Shrink Striving to achieve a wasteSleeve Range free world, Unilever is building partnerships to drive an inclusive 250mℓ won the circular economy by rethinking Gold medal. Entered every step of each product’s lifecycle, from packaging by Unilever, New design and manufacturing to Era Labels and Berry consumer use, collection and recycling. Astrapak, the range

different with the substrate categories

support from sponsors,

tending to be focused more on the

which demonstrate their

technical superiority of the packaging’s

commitment to the industry

manufacture and conversion. According

in a meaningful way. This year, the

campaign. This packaging celebrates

to Bill Marshall, national secretary of

flagship sponsors were Propak, Sappi

eight different countries and ethnic

the Institute of Packaging South Africa

and Nampak whose continued

groups. The sleeves are printed in-line

(IPSA) and Gold Pack judge himself, the

support has come to underpin the

using a specialised combination of

judges look for the excellent execution

awards programme. Additional

gravure and flexographic printing.

| JANUARY 2020 | P C Review

is produced as part of Unilever’s ‘Journey of the Jar’

EVENTS The Bronze medal was awarded to Teqal Creative Packaging and Canway Products for the Oh So Heavenly 50ml face cream jar. The clever use of a combination of polymers has maximised the visual impact of this pack, while reducing costs and retaining functionality. A clear outer lid, combined with a high-gloss silver foil band on the jar, add to the pack’s aesthetic appeal. According to Sean Kirkham, sales and marketing director of Teqal, it took a passionate and experienced team to put together this new jar for the Oh So Heavenly face cream. ‘During the early stages of product development, it was clear the Canway team had a well-defined understanding of its target

Bill Marshall pictured with representatives from Unilever, who accepted the award for the Judge’s Special Mention

market’s needs for premium quality and value.’ In the Household Products (including domestic goods and others) category, Unilever bagged another Gold medal

in 2010, it has three main goals, one of which is to halve the company’s environmental impact by 2020. The award for Judge’s Special Mention

for the Sunlight Dishwash 750 and 400mℓ

for Sustainability doesn’t form part of

products. Entered by Unilever, Serioplast

the category awards and is instead a

and Extrupet, the packaging incorporates

separate prize bestowed on companies

100 percent rPET, compared to the

at the discretion of the judges.

50 percent rPET used in the previous design. It also saves the use of some

Improving waste management

1 800t of virgin polymer. In harmony

By 2025, Unilever has confirmed it will

with Unilever’s Sustainable Living Plan,

halve its use of virgin plastic, by reducing

this iconic brand is leading the way in

its absolute use of plastic packaging by

educating South African consumers

more than 100 000t and accelerating

about the merits of recycling and

its use of recycled plastic. It will also

encouraging others to follow in

help collect and process more plastic

its footsteps.

packaging than it sells.

A leader in sustainability

continue to work towards its existing

Unilever also received the Judge’s

commitment, made in 2017, to ensure

Special Mention at the Gold Pack

all its plastic packaging is 100 percent

Awards 2019 for its Unilever Sustainable

reusable, recyclable or compostable

Living Plan.

and includes a minimum of 25 percent

Su zi Moore of Packag ing & Pri nt Media wi th Sean Kirkham of Teq al

The multinational brand owner will

‘We pride ourselves in developing an in-depth understanding of what

recycled plastic. The Sunlight Liquid, Dawn Body Lotion

consumers want and utilise our expertise

and Comfort Fabric Conditioner bottles

in science and technology to innovate

are fully recyclable, and examples of

boldly for people and the planet,’ says

packaging already made from 100

Jennifer Cromie, R&D director at Unilever.

percent recycled plastic. This makes

‘The awards, which we humbly accept,

Unilever the first major global consumer

are testament to the relentless efforts of

goods company to commit to an absolute

the R&D team and our commitment to

plastics reduction across its portfolio.

sustainable growth. For the judges to sit

Extrupet, one of the largest and

Anita Raath, New Media advertising sales executive with Abby Vorster, editor of P&C Review

up and take notice of the impact of our

most advanced recyclers of rPET bottle

initiatives through Unilever’s Sustainable

materials on the African continent,

to improve legislation around waste

Unilever is also working with partners

Living Plan, must mean we are doing

commended Unilever on being a

management. One of the ways in

something right.’

frontrunner in the use of rPET in South

which this is being achieved is by

The Sustainable Living Plan sets out

Africa along with its commitment to

integrating reclaimers or ‘waste pickers’

to decouple Unilever’s growth from its

improving packaging sustainability

into the recycling economy and ensuring

environmental footprint, while increasing

and performance at the 2019 Gold

they are paid for the valuable service

its positive social impact. Launched

Pack Awards.

they provide. •

P C Review | JANUARY 2020 |

COMPANY FOCUS

IMCD takes its first steps to enable sustainability Every journey starts with the initial steps, as IMCD reveals in its first sustainability report released in 2019. This report lifts the veil on all non-financial data of the company, including its social, safety and environmental performances of 2018. It also highlights significant local initiatives, from efforts to optimise its supply chain to helping local communities.

hile compiling its first

Ultimately, it sounds as if shifting to

to find sustainable alternatives or more

sustainability report,

greener options is the way to go, so why

innovative solutions. Subsequent to

calculating greenhouse gas

doesn’t everyone follow this path? Truth

concrete analyses of data concerning

emissions and documenting

is, it’s not that easy for every market.

production and use phases, these raw

current achievements in terms of positive IMCD realised it has a bigger role to play

Progressive versus conventional

in sustainability. As a global leader in

Some industries, such

the sales, marketing and distribution of

as personal care, are

speciality chemicals and food ingredients,

ready to embrace

IMCD realises it can make a far bigger

sustainability as

impact by looking outside of its own

they are driven by

operations and shifting the product offering

consumers concerned

towards more sustainable raw materials.

about the environment.

environmental and social impacts,

Harnessing its deep knowledge of the

They’re also pushing big

DID YOU KNOW? IMCD believes

materials will be promoted as suitable alternatives that provide environmental, social and economic

sustainability goes beyond benefits throughout regulatory compliance their entire life cycle and current profitability and success. A sustainable global when compared to economy, according to the mainstream solutions company, should combine long-term profitability, currently on the market. social justice and The added value for environmental care – now and into its customers will not only the future.

markets in which it operates and the key

brands and multinationals

players, as well as through its technical,

to reach a higher level of

be in terms of their reduced

marketing and supply chain expertise,

naturality in their products by using

reputational and cost saving measures.

IMCD could be a one-stop source for

biodegradable ingredients and

For example, using recycled plastics

customers who need to lower their

more sustainable packaging options,

in new buildings is proven to be less

environmental footprint. The company is

which would lower their contribution

expensive than their virgin countertype

equipped to provide products either with

to plastic pollution. More and more

or adding a processing agent to a

a lower toxicity profile, reduced carbon

consumers choose their personal

reagent can shorten heating time and

footprint, or which require less energy or

care brands based on their social and

lower energy consumption.

water when using the finished product.

environmental impact. They have the

Looking at the reasoning behind the

environmental impact but also

power to shift sustainability trends by

New green portfolio

need for more sustainable products,

being vocal about environmental issues

The IMCD portfolio of sustainable

it’s clear IMCD could make a major

on social media.

products will be launched this year.

contribution to achieving climate change

Yet there are other more conventional

Every product within this portfolio will

targets. More sustainable products are

industries where the choice of raw

be backed by tools and data to assist

also proven to be a sound investment.

material is driven by price and traditional

its sales force in guiding customers

IMCD’s efforts to provide more efficient

habits. This is where IMCD has the ability

to select the right alternative to a

products can help its customers lower

to affect change despite the effort

product already in use. Using relevant

their costs and reach new consumers

required to do so. As a first step, the

methods of measuring and assessing

concerned about environmental issues.

company will work closely with suppliers

environmental impacts, IMCD forecasts

| JANUARY 2020 | P C Review

COMPANY FOCUS

IMCD forecasts the overall carbon footprint associated with its offering of sustainable products will decrease in the years to come chain to laboratory and sales functions. They are then guided on their subject choices and the admission requirements of their preferred tertiary institution of study, as well as equipped with soft skills such as time and stress management, presentation skills, interview techniques and how to create a professional CV and complete applications for university and financial aid, if necessary.

Making a difference For three decades, the Look Good Feel Better programme has been dedicated to helping people with cancer cope with the appearance side effects of their

the overall carbon footprint associated

communities in one of more than 200

treatment. Since 1989, the programme

companies over a three-year period.

has empowered two million people in

The TechnoGirl initiative is helping to close

27 countries around the world to reclaim

with its offering of sustainable products will

the gender gap by combining technical

a sense of control, confidence and self-

decrease in the years to come.

learning and mentorship with life skills

esteem, which are central to wellbeing.

Besides delivering safe and sustainable

education and empowering girls to make

In South Africa, the programme is made

products, IMCD is also actively involved

informed choices to prevent HIV, teenage

possible through the collaborative effort

in regional social responsibility

pregnancy and gender-based violence.

of Look Good Feel Better South Africa, the

initiatives to contribute to the welfare

Female learners ranging from grade 9

of local communities and improving

to 11, from economically disadvantaged

charitable arm of the cosmetics industry association – the Cosmetic, Toiletry &

their conditions.

backgrounds, are chosen and assigned

Fragrance Association (CTFA) – members

to participating companies, which they

of the CTFA and other generous sponsors.

Empowering young women

visit during school holidays. Although the

IMCD South Africa is a proud programme

purpose is primarily job shadowing, the

IMCD South Africa sponsors raw materials

partner with TechnoGirl, an initiative

mentoring programme is much broader.

to renowned personal care brands to

created by Unicef in partnership with the

During the three-year period these

Contributing to its ongoing success,

manufacture the cosmetics and skin

Uweso Trust and the National Department

learners spend time with the IMCD

and sun care products they donate to

of Basic Education. The programme

South Africa team, gaining exposure

Look Good Feel Better for the workshops

places academically gifted high school

to every single job function within the

hosted at hospitals and clinics around

girls from underprivileged rural and urban

company, from admin and supply

South Africa. The company also actively supports the foundation by participating in its annual golf days and providing sponsorships for these events. With local projects and other initiatives worldwide, IMCD is committed to the strong idea of a sustainable future. Through supply chain optimisation, cooperation with reliable partners and developmental projects to progress the social fabric, IMCD will achieve its

TechnoGirl in-programme learners, Kefilwe Moloi and Basetsana Mogagabe with IMCD South Africa’s customer solutions manager, Ana Da Costa, photographed in IMCD South Africa’s Ethnic Care centre of excellence

TechnoGirl in-programme learners Katlego Tsatsi and Promise Mamome with IMCD South Africa’s applications technologist, Gladys Syebele, photographed in IMCD South Africa’s food technology laboratory

ambitious sustainability targets. •

IMCD – www.imcdgroup.com

P C Review | JANUARY 2020 |

PACKAGING PROFILES

– a specialist in plastic Contact details

process of plastic tubes for use in the

Tel: +27(0)81 468 9600

cosmetics industry. Its equipment is

Plastic squeeze tubes in development

Email: sales@designaplastics.co.za

geared towards continuous extrusion

• a range of 25 and 50mm diameter

Web: www.designaplastics.co.za

moulding, heading injection moulding,

squeeze tubes, set to be launched in the

Unit 5, Dura Industrial Park

capping and screen printing, to enable

second quarter of the year.

90 Escom Road, New Germany, KZN

quick turnaround times.

Find us here: https://goo.gl/maps/ nfLn3NC8Fj5YM9uX8

The premium two-layer tubes are manufactured from a polyethylene blend of materials. Designa understands that squeeze tubes are

Company description

specific to each individual customer’s

Designa is a one-stop shop for converting

needs, which is why customers can

concepts into complete finished products,

customise their tube and cap colours

from design and drawing to prototyping

as well as the screen printing on their

and manufacturing. For over two decades,

tubes, up to four colours and with

Designa has been at the forefront of

a varnish application. While tube

product design and manufacturing

diameters are set, the length of the

of plastic products. Founded in 1992,

tube can be adjusted to the customer’s

Designa’s focus was on custom injection

specific needs.

moulding. Over the years, its focus has shifted to rigid packaging for the cosmetics industry. Designa is a go-to South African

Plastic squeeze tubes in production • 30mm diameter squeeze tube with an

manufacturer for custom made plastic

aluminium foil anti-tamper seal and a

tubes for the cosmetics industry and for

threaded screw cap

therapeutic creams and ointments. The company offers exceptional customer service and quick turnaround times. Whilst its focus is currently on the expansion of its tube manufacturing division, Designa also offers plastic manufacturing solutions for brand owners. These needs are met with its over 40 production machines for injection moulding, injection blow moulding and injection stretch blow moulding, as well as screen and pad printing and labelling.

New products Driven by innovation, Designa now specialises in manufacturing plastic squeeze tubes. The company has a complete set-up of machinery offering a comprehensive bulk manufacturing

| JANUARY 2020 | P C Review

• 40mm diameter squeeze tube with a flip top cap.

Stock products • clear PET jars in 60, 100 and 130mℓ sizes with standard coloured caps • round roll-on bottles with a 60mℓ fill capacity and a large roll-on ball and cap • clear 60mℓ PET bottles with a puffer and lid.

WWW.DESIGNAPLASTICS.CO.ZA

PACKAGING PROFILES Contact details Rotolabel Cape Town 36 Thor Circle, Viking Place, Thornton Tel: +27 (0)21 532 55 40 Rotolabel S&N Labels 48 Forge Road, Spartan, Kempton Park Tel: +27 (0)11 975 8141 Email: Grant@rotolabel.co.za OR admin@rotolabel.co.za

– our proudest label is trust

Web: www.rotolabel.co.za

Company description

Liner recycling programme

Founded in 1982, Rotolabel has gained distinction in the supply

Rotolabel is pushing the

of world-class self-adhesive

boundaries in sustainability.

labels. Rotolabel was acquired by

In conjunction with Avery

the Bidvest Group in 2008, and

Dennison, it is one of the first

today represents the Labelling

companies in South Africa’s

Solutions division of Bidvest Paperplus

labelling industry to become

– a leading supplier of printing,

FSC compliant.

communications, packaging and

These two companies have

labelling solutions in southern Africa.

partnered with an exciting new

Rotolabel specialises in flexographic,

initiative, which is revolutionary in the

letterpress and digital print

• Retail

South African label industry. The initiative

technologies, allowing the company to

• Security

will result in tonnes of liners by diverted

print labels of consistently high quality

• Track and trace

from ending up in our country’s already

on a range of substrates with a variety

• Logistics and warehousing.

over-subscribed landfills.

XpandalabelTM booklet labels

is available for PET and glassine

is state-of-the-art finishing, which

With Rotolabel’s solution for all booklet

liners and is currently active in many

provides hot and cold foiling, silkscreen

and leaflet label needs, customers can

countries worldwide. The liner recycling

and high-build, as well as varnishing

look forward to high quality, competitively

programme will be rolled out in Cape

and laminating – everything you could

priced booklet labels. Xpandalabel TM

Town. Once the proof of concept

wish for in designing a world-class label.

booklet labels can be designed and

is realised and manufacturers and

die-cut into various shapes and sizes,

consumers see its benefits, it will be

Major products and services

and the leaflet length is suitable for all

rolled out nationally and to the industry.

• Blanks

informational needs and only limited by

• Ribbons

the final folded thickness.

of finishes. Complementing its printing resources

• Thermal printers

The liner recycling programme

Large amounts of information can

The liner is collected from customers and taken back to the Rotolabel site to be compacted. Avery Dennison then

• Barcodes and scanners

be permanently attached to the label

collects the compacted liner and loads it

• One to nine colour printing

and the container, eliminating the

into a container to be sent to India where

• Silkscreen

need for separate package inserts and

it is made into tissue paper.

• High-build

informational booklets. The elimination of

• Embossing

the package insert can also potentially

Certifications

• Digital printing on HP Indigos

lead to the elimination of the carton –

• FSC compliant

• Personalisation

and result in substantial cost savings.

• ISO 22000

• Various substrates

Further savings can also be seen through

• ISO 9001

• Wrap-around labels

the shortened packing process on the

• Mellow Colour Proficient Printer Status.

• Applicators and dispensers.

production line.

Key markets and USPs

labels, Xpandalabel TM is also great for

• Food and beverage

promotions, competitions, terms and

• Personal care

conditions, recipes, give-aways and

• Wine

coupons, and can be applied to existing

• Pharmaceutical

packaging for limited time offers.

In addition to pharmaceutical

| JANUARY 2020 | P C Review

SPECIALITY INGREDIENTS

New therapeutic approach to healthy ageing We start ageing from the day we are born. Through a complex system, our bodies chronologically renew cells and change their shape, adjusting the conditions of ageing. This is known as Epigenetics – the root of inspiration for a new active from Chemyunion. Identifying the markers

Apple and ginger extract

DNA methylation is perhaps

Chemgrit Cosmetics, has developed

the best-known epigenetic

Agen, a new active ingredient based

marker, but its challenging to

on epigenetics. Through the regulation

use in skin ageing treatments

of miRNA (micro-RNAs), Agen effectively

due to the difficulty of

reduces the signs of skin ageing.

identifying its triggers. Another mechanism, which has gained greater relevance in epigenetics, is the

Chemyunion, represented locally by

Agen is inspired by the natural nutritional components known to affect health and ageing. It is composed of a synergistic blend of apple extract (Malus

presence of microRNAs. This appears to

domestica) and supercritical ginger

be the most indicated for a therapeutic

extract (Zingiber officinale).

approach to skin ageing since more

In vivo test results show Agen contributes

than 800 miRNAs have already been

to a significant improvement in skin

ntrinsic and extrinsic factors

identified along with their impact on

firmness and elasticity after 14 days, 29

contribute to ageing, the former

protein metabolism.

percent re-densification of the dermis and

being hereditary while the latter, the environment, kick starts

RNA (ribonucleic acid) is the main

thickness after 60 days. The key benefits

control of cellular protein synthesis.

of the active ingredient include wrinkle

Composed of a single strand, the

reduction; improved skin resistance, integrity

RNA is produced in the nucleus of

and regeneration; and the stimulation of

is known as epigenetics, a

the cell and subsequently routed to

cell renewal and differentiation providing

phenomenon capable of modifying

the cytoplasm for protein production.

younger looking, healthier skin. •

the transformation process at a genetic level. This process of genetic change

certain genes through external factors

The ncRNAs are not translated into

such as pollution and stress. It changes

proteins, but many of them are able

the way our cells read the original genes

to regulate gene expression or even

and functions as a gene switch, stimulating or silencing genes.

a 40 percent improvement in epidermal

molecule involved in the process and

| JANUARY 2020 | P C Review

protein production, acting as a kind of genetic switch.

Chemgrit Cosmetics – www.chemgritcosmetics.co.za Chemyunion – www.chemyunion.com

SPECIALITY INGREDIENTS

Formulating sustainable products More cosmetics manufacturers are formulating natural and eco-friendly products as public interest in sustainability increases. Ramya Sriram, digital content manager of Kolabtree, a freelance platform for scientists, discusses trends and developments in sustainable cosmetics.

onsumers aren’t just interested

and refining their

chemist can help you find the perfect

in the product; they’re also

formulations all the

substitute for microbeads.

interested in the process.

time. Lush is pioneering

The cosmetics industry is not

zero packaging by making

Vegan beauty

known for being eco-friendly, with its use of

its products in solid form and

The number of people living plant-based

excessive, non-recyclable packaging to a

in January 2019 the brand

lifestyles is higher than ever. Consumers are

perceived lack of transparency over ethical

opened Britain’s first packaging-free

also investing more in cruelty-free beauty

practices. However, beauty is waking up to

cosmetics shop.

and skin care products, made with plant-

consumer demand and the natural and

Many companies are also participating

derivatives and that don’t include animal

organic beauty market is estimated to reach

in the #waterlessbeauty campaign. Water

products. This is one of the latest trends in

US$54 billion by 2027.

is the cosmetics industry’s most used raw

natural cosmetics and these ingredients are

material. However, concerns of demand for

found in products ranging from moisturisers

reformulating products for cosmetics

water outstripping supply are becoming a

and cleansers to soaps and fragrances.

businesses by including more natural and

harsh reality. L'Oréal has committed to a 60

environmentally friendly emulsifiers and

percent reduction in water consumption

you can also ensue your products are

ingredients. If you do this too, your brand

per product by 2020, while Unilever is

vegan-friendly. This can be done by

will be able to meet the growing salience

committing to halving the water associated

suggesting substitute ingredients not

of sustainability. But, before you jump into

with the use of its products, also by 2020.

derived from animals. If you are planning

Development chemists are now

developing your eco-friendly cosmetics, there are a few trends worth watching.

With the help of a formulation chemist,

on entering the world of natural beauty,

Beyond microbeads

creating vegan-friendly products is a step in

Since the EU and UK ban on

the right direction. •

Sustainable cosmetics

microplastics in cosmetics came into

At the heart of the natural cosmetics

effect, natural beauty has been leading

ABOUT THE AUTHOR

movement is the value of sustainability.

the way in offering natural, sustainable

Ramya Sriram has more than

Beauty brands and manufacturers now

alternatives to microbeads in skin

10 years’ experience spanning

care and scrubs. Companies are now

content marketing, writing

producing products using oats, salt,

and editing. She is currently

dairy and even coffee as substitutes to

digital content manager at

ensure regulatory compliance.

Kolabtree, a start-up based in London,

realise it’s no longer a fad and that consumers expect transparency over their sustainability programmes before choosing whether or not to buy. Companies appear to be

One purpose of microbeads is to exfoliate the skin. However, it’s possible

united on reducing the impact

to get this effect without using plastic.

of plastic pollution, changing

If you are producing cosmetics or skin

their packaging strategies

care products, a freelance formulation

UK, which helps businesses hire freelance scientists.

Kolabtree – www.kolabtree.com

P C Review | JANUARY 2020 |

SPECIALITY INGREDIENTS

Innovative ingredients inspired by nature Danlink Ingredients, a distributor of speciality ingredients and additives for the food industry, has diversified into personal care. The company introduces its newest principal, Kialab, an Italian producer of smart ingredients for personal care applications.

orking in conjunction with universities, start-ups and R&D centres, Kialab develops and markets new ingredients

for the cosmetics industry. The company focuses on ‘nature-like’ ingredients, often inspired by the concept of biomimicry, or it valorises agri-food by-products and biomasses, isolating value-added molecules and positioning them as high-value ingredients for cosmetics.

Sugarderms are saccharides obtained using a bio-fermentation process application i.e. treated armpit and non-

Sugarderm H2O monosaccharides have

is the Flavocare product family, based

treated contra-lateral armpit. Test results

high capacity to bind water and quick

on propolis-derived raw materials and

showed an odour reduction of 61 percent

release capabilities because of the small

produced using a patented technology of

with the formula containing Flavocare

clusters they form. Sugarderm Age, with the

a partner company. Flavocare extracts are

Hydroglyceric, making the active

presence of trisaccharide, allows for the

said to be particularly rich and standardised

ingredient highly suitable for formulating

formation of bigger clusters with a different

in high value polyphenol fractions separated

natural, safe and efficient deodorants.

coordination of water, giving deeper

One of the first ingredients it developed

hydration to the skin (in vivo).

from the remaining or least desirable parts of propolis, such as the resin and wax.

Nutrients for the skin

To evaluate the anti-ageing efficacy of

Sugarderm is based on a number of rare

Sugarderm, Kialab tested both the H2O and

Flavocare extracts to identify less explored

mono and tri-saccharides, which Kialab

Age variants on a full thickness skin model,

areas of application. In vitro tests were

has been studying over the past few years.

evaluating each variant’s ability to stimulate

carried out successfully to determine

The mono and tri-saccharides originate

glycoproteins as collagen IV, decorin,

the antioxidant, antibacterial and anti-

from fermentation processes and display

fibrillin and the protein, elastin. Sugarderm

inflammatory activities of the extracts, while

powerful skin care activity, primarily

H2O showed a huge increase in the gene

the in vivo trials showed the extracts have

enhancing skin density and elasticity.

expression of collagen IV, elastin and fibrillin

Kialab conducted in vitro and in vivo on

multifunctional benefits. These include

Sugarderms are saccharides obtained

at 24 hours and the initial inhibition of

deodorising efficacy, helping to reduce

using a bio-fermentation process. These

decorin subsequently increased significantly

acneic lesions, regulating sebum,

saccharides have a purity of more than

within 48 hours. Sugarderm Age showed

soothing skin, reducing TEWL and anti-

95 percent. The concept is very much in line

better activity on the aforementioned

pollution benefits.

with the new trend of cosmetics products

markers within 24 hours.

based on glycobiology. Kialab currently

In vivo test results show Sugarderm

suggested by the encouraging results of the

offers two variants in the product family:

Age has an effective anti-ageing action

bacterial inhibition tests on Staphyloccocus

• Sugarderm H2O (INCI: Arabinose and

determined on several parameters such as

The deodorising power of Flavocare,

hominis and aureus was evaluated using

Fucose), is a mixture of highly pure

thickness, viscoelasticity and suppleness.

an in vivo sniff test. The protocol consisted

monosaccharides, obtained through a

The skin was also smoother and more toned

of observations at eight hours and 24 hours

fermentation method

as a direct result of the stimulation of the

from the application of one deodorant

• Sugarderm Age (INCI: Arabinose and

micro-emulsion containing 1.5 percent

Fucose and Fucosyllactose), is a mixture

Flavocare Hydroglyceric, on a panel of

of highly pure oligosaccharides and

20 subjects. Test were conducted under

monosaccharides, also obtained through

controlled conditions using asymmetrical

fermentation method.

| JANUARY 2020 | P C Review

elastin and collagen network. •

Danlink Ingredients – www.danlink.com Kialab – www.kialab.it/en

We are a team with more than 20 yearsâ&#x20AC;&#x2122; experience in R&D, Regulatory, Marketing and Sales. Since 2012 we operate in Italy and abroad in the Personal Care business offering innovative ingredients and developing tailor-made smart compounds. Constructive dialog and teamwork with a look into the future are the key of our success.

Kialab is represented in South Africa by:

Danlink Ingredients is distributor of speciality raw materials to the Personal Care Industry. Representing only reputable and reliable suppliers, the company strives to provide world class service with technical and commercial support.

(JHB) 011 7047261Â Â (CPT) 021 9139818 đ&#x;&#x201C;§đ&#x;&#x201C;§ info@danlink.com î&#x201E;Ť www.danlink.com

SPECIALITY INGREDIENTS

Get a lighter, more even complexion with rainbow algae

Codif laboratories continues to push the boundaries of the cosmetics and bio-technological industries, drawing inspiration from plankton, seaweeds and flora. The company’s newest active ingredient, Cywhite G is proven to inhibit melanogenesis, promoting more luminous even tone skin.

n 2018, Martin Lopez-Garcia of the

up to 60cm in length by the end of spring.

International Iberian Nanotechnology

Its branches are covered in spines, which

Laboratory and his team published a new

become iridescent when placed in water.

study on the phenomenon of iridescence

The colour of the branches changes from

in algae. The study found the iridescence is

green to violet passing through blue.

due to the regular stacking of fat balls within

Cystoseira tamariscifolia, or rainbow algae, changes in colour when exposed to light of varying intensity

foreshore to the place of harvest, where

pockets localised in the epidermal cells.

Rainbow algae

Cystoseira tamariscifolia is collected by

Their function is to ensure optimum diffusion

Cystoseira tamariscifolia occurs on

hand in about 10cm of water, requiring

of light to the chloroplasts. This effect has

the coasts of the Channel and the

the use of a flat-bottomed boat to store

only been observed before in certain

Atlantic, spanning from the British Isles to

the algae during harvesting.

animals such as chameleons.

Mauritania via France, Spain, Portugal,

This adaptation seems to be a response

To minimise waste and promote

the Canary Islands and the north African

regrowth, the shoots are cut with a knife,

to environmental factors. The algae are

coasts (or western Mediterranean).

leaving the epiphyseal perennial part in

exposed to light of varying intensity which

Species-specific eco-systems such as

place. The algae are shaken in the water

changes with the tide and depth of the

Cystoseira tamariscifolia are harvested

to remove sand and periwinkles and

water and enables the algae to improve

where other species of economic interest

bagged in potato sacks. Thereafter they

the diffusion of ambient light.

are not present. The harvesting area is

are pre-faded on racks to be dehydrated

Cystoseira tamariscifoliais a brown alga

located a few kilometres from the coast.

naturally. Drying can be also completed

belonging to the order of Fucales, reaches

The harvester drives a tractor along the

in an electric dryer at 50°C. The goal is to

GLOBAL COSMETIC PRODUCT REGULATORY COMPLIANCE SOLUTIONS Intertek provides a comprehensive range of services for beauty and personal care products to ensure quality, safety, efficacy and regulatory compliance. Partnering with Intertek helps brands and producers to speed up their international growth, optimise the quality and safety of their supply chain and reduce total costs. Our Services Include: • Literature Review & Data Collection • Toxicological Profiles of Ingredients • Regulatory Dossiers • Toxicological Safety Assessment • Labelling Reviews

| JANUARY 2020 | P C Review

MORE INFORMATION +44 116 263 9621

• • • • •

Microbiology & Stability Testing Cosmetic Packaging Analysis Causality Assessment Compliance Solutions Regulatory Support

hersuk-regtox@intertek.com

intertek.com/cosmetics/ global-reg-compliance-forcosmetic-products/

SPECIALITY INGREDIENTS promote natural drying. As a result, the

for their maturation, resulting in a 25

harvest periods are not only reliant on the

percent decrease in PMEL 17 (PMEL17 =

role of cathepsin L2 in the process of

tides but also to the weather.

PreMELanosome protein).

melanosome degradation. Research

The extraction is processed using a

Tyrosinase is the enzyme that synthesises

Many publications suggest the primary

conducted by Codif laboratories has

patented enzymatic cocktail of specific

melanin. Its expression is modulated by

shown that UV exposure results in a 26

sugars and proteins, which are neither

different genes. Cywhite G stimulates

percent decrease in CTSL2.

GMO nor of animal origin. At the end of

the expression of the DKK1 gene, whose

the process, the enzymes are inactivated

role is to limit the activity of tyrosinase.

stimulates the expression of Cathepsin L2

by heating them up to 80°C.

The extract also slows the transfer of

by 35 percent. By acting on the key points

melanosomes to keratinocytes. SCTE

of melanin activation and synthesis, and

a cellular concentrate, Cywhite G with

is a tryptase strongly expressed in

on the degradation of melanosomes,

skin brightening properties. Cywhite

keratinocytes. It is known to activate the

Cywhite G has a lightening action. After 16

G INCI: Glycerin (and) Water (and)

PAR-2 factor involved in the phagocytosis

days of topical application of Cywhite G, a

Cystoseira tamariscifolia extract (and)

(absorption) of melanosomes by

decrease in the amount of melanin in the

Phenoxyethanol. The active is also

keratinocytes. The extract limits the

epidermis was noted.

available in a Cosmos approved

transfer of melanosomes via a decrease in

version, INCI: Glycerin (and) Water (and)

the enzyme SCTE.

From this rainbow alga, Codif extracts

Cystoseira tamariscifolia extract.

Cystoseira tamariscifolia extract

This truly unique ingredient from the sea, with its chameleon like properties to decrease global pigmentation, is ideal

New brightening targets

for formulations to address pigmentary

Melanosome absorption

The role of cathepsins in the degradation

disorders of the skin.

Used in a formulation at one to 1.5

of melanosomes is more and more studied,

percent, Cystoseira tamariscifolia extract

particularly those of cathepsin L2 (CTSL2).

are available in South Africa from Vantage

prevents the maturation of melanosomes.

These are hydrolytic enzymes involved in

Specialty Chemicals. •

It’s only after the maturation phase that

epidermal differentiation. The expression of

the melanosomes are able to synthesise

CTSL2 is very clearly increased in light skins

melanin. Yet Cywhite G decreases the

whose melanosome degradation activity is

expression of the molecule responsible

greater than in dark skins.

Active ingredients from Codif laboratories

Codif laboratories – www.codif-tn.com/en Vantage Specialty Chemicals – www.vantagegrp.com

P C Review | JANUARY 2020 |

SPECIALITY INGREDIENTS

A modern take on historical biological resources For centuries, indigenous and rural communities worldwide have been dependant on biological resources to treat skin and health ailments. Today, this knowledge is often used for academic research and the development of commercial products.

otanica Natural Products’ main

and the fixing of atmospheric carbon.

business activity is the cultivation

Traditionally, the fleshy leaves have been

of the indigenous South African

used to treat dermatitis and chronic sores.

plant, Bulbine frutescens, as

Bulbine frutescens is also an indigenous

well as Moringa oleifera. It has also

succulent. Its clear gel is similar in

established a plantation of 250 000

appearance and consistency to aloe vera

Spekboom (Portulacaria afra) to offset its

gel and has been widely used in traditional

carbon emissions and reduce soil erosion.

medicine as an effective remedy for topical

The company is currently investigating

ailments, including burns, wounds, cuts,

the potential of Spekboom to combat

abrasions, rashes and boils. Although there is

dermatological conditions.

An aerial view of Botanica Natural Products’ production facility and plantation, based in Alldays, Limpopo

Moringa oleifera, also known as the ‘miracle tree’, is a fast growing, drought resistant tree, native to the sub-Himalayan

Egyptian, Roman and Greek communities

region. The tree has been used for a

used Moringa for the treatment of dry skin.

variety of purposes and is widely known

Spekboom is an indigenous succulent

for its range of impressive properties.

shrub commonly used in veld restoration

substantial traditional knowledge associated with the use of this species, Botanica Natural Products is the first commercial producer of this water based gel. There is evidence of Moringa oleifera, Portulacaria afra and Bulbine frutescens being used in southern African traditional

AT LAST !!

AN EVENT LONG OVERDUE IN SOUTH AFRICA....... SUPPORTED BY

THE DECK. WANDERERS STADIUM, CORLETT DRIVE ILLOVO, JOHANNESBURG MAY 8th, 9th, 10th 2020

MEDIA PARTNERS

EXHIBITION PROFILE Food & Beverages Ingredients & Raw Materials Vegan - Halaal - Kosher Supplements Cosmetics & Beauty products Personal care & Hygiene products Home care Organic gardening & farming .....and more

| JANUARY 2020 | P C Review

Local & International Buyers

50 Bo % S ok OL No D w!

Over 10 000 consumer visitors to sell to Exhibitor Enquiries: John.t@satp.co.za

SPECIALITY INGREDIENTS The indigenous succulent shrub, Spekboom

medicine for skin care

activity of each species was

effective against the ringworm pathogen.

applications. As a result,

tested individually and in

Moringa oleifera and Portulacaria afra

Botanica’s success is

combination. The anti-infective

combined showed the best activity against

largely attributed to the

properties were then compared

the acne pathogen. The greatest synergistic

traditional knowledge

against each of the

held by local and

results. Toxicity was

indigenous communities.

also examined as

effects were seen with Portulacaria afra combined with Bulbine frutescens, against a bacterium that causes smelly feet.

For this reason, since its

combining these

inception in 2009, the company has

species could

oleifera and Bulbine frutescens

possibly reduce any

demonstrated no toxicity at all. When

worked closely with the Department of Environment, Forestry and Fisheries to

toxicity, if present.

ensure knowledge holders are equitably compensated for their expertise, innovations and practices associated with these medicinal plant species.

For the purpose An example of how Bulbine frutescens could be used in a skin care application

When examining toxicity, Moringa

Portulacaria afra, which demonstrated some toxicity alone, was combined

of the study,

with Bulbine frutescens, the toxicity was

fresh plant

reduced by half.

samples were

These studies demonstrate that some

obtained from Botanica and processed at

pharmacological effects are enhanced in

Research for product development

the university for antimicrobial and toxicity

combination. The plant species also show

testing. For the antimicrobial studies, the

potential when looking at treatments for

Professor Sandy van Vuuren from

plant species were tested against the

acne and ringworm. To further contribute

the Department of Pharmacy and

following bacteria:

to this research, Botanica has plans to

Pharmacology at the University of

• Cutibacterium acne, responsible

continue working with the University of

Witwatersrand has investigated

for acne

Witwatersrand to determine the anti-

whether the combination of Moringa

• Candida albicans, causing fungal

inflammatory effects of the three plant

oleifera, Portulacaria afra and Bulbine frutescens would have a superior effect on skin ailments than each individual species used alone. The antimicrobial

infections on the skin

species when combined. •

• Trichophyton mentagrophytes, a fungus that causes ringworm. When tested alone, the samples were most

Botanica Natural Products – www.botanica.africa

Tel 011 608 4944 Fax 011 608 4948 Email sales@sensetek.biz

Sensetek.indd 1

2017/03/02 11:50 AM

P C Review | JANUARY 2020 |

SPECIALITY INGREDIENTS

Promoting sustainable supply chains for responsible products Increased environmental consciousness has prompted the cosmetics industry to develop new sustainable solutions that don’t compromise on performance. With programmes for the sustainable cultivation of renewable raw materials, BASF is helping manufacturers provide consumers with responsible skin and hair care products while benefitting rural communities.

ASF Care Creations recently

fruits have long been

launched three active ingredients

used to treat dysentery

DID YOU KNOW?

and Rambuvital (INCI: Maltodextrin [and]

Dong Nai province in In 2019, BASF celebrated 25 Southeast Vietnam. years of having a sustainability due to their richness in Over an area of three strategy in place. In 1994, the company adopted its Vision 2010, iron, vitamin C, fibre hectares, the gardens which oriented BASF towards and antioxidants. feature around 200 the principles of sustainable The rinds contain rambutan trees aged development. At that time, it was one of the first companies compounds with 25 to 30 years. When worldwide to publicly antioxidant properties cultivated well, the trees commit to sustainable development. and the seeds have been can live for up to 100 years,

Nephelium Lappaceum [Seed] Extract).

shown to decrease unwanted

Extracted from the spiny fruit peel, the

fat. Even the pulp is known to have

evergreen leaves and the seeds, the

health benefits – it boosts energy and

income stream for years to come. To

bio-actives offer skin and hair protection

immunity, prevents diseases and helps

make this possible, BASF encourages and

against pollution, dehydration and signs

eliminate free radicals.1

emphasises organic, sustainable farming

based on the Southeast-Asian rambutan tree, namely Nephydrat

(INCI: Glycerin [and] Water [and] Nephelium Lappaceum Peel Extract), Nephoria (INCI: Maltodextrin [and] Nephelium Lappaceum Leaf Extract)

of ageing. What’s more is the impact of

Despite rambutan’s wide range of

providing the rural communities from the region with a reliable

practices, and implements measures to

these bio-actives goes far beyond the

benefits, farmers primarily sell the juicy

personal care industry. With its dedicated

fruits. Thanks to BASF’s interdisciplinary

Rambutan Programme, launched in

innovation platforms, they can now

partners from the region, both gardens

2015, BASF has established a socially and

also make use of the parts of the plant

received organic certification in 2017,

environmentally responsible supply chain

which mostly go to waste. This upcycling

making them the first certified gardens

for bioactive production in Vietnam.

programme gives farmers an opportunity

of their kind in Vietnam. BASF also set up

to generate a new income stream with

a dedicated rambutan team to oversee

an above average income. As a result,

maintenance of the organically certified

the cooperation has a positive impact on

gardens and harvest the fruit between

Vietnamese rural society.

July and September. The team sorts stems,

Upcycling to benefit farmers The rambutan tree, native to Indonesia and Malaysia, is renowned

ensure organic farming compliance. Thanks to the joint efforts of BASF and

leaves and fruits, removes the pericarp,

throughout Asia for

Sustainable, organic sourcing

separates pulp and seeds and leaves the

its various health

For its Rambutan Programme, BASF

parts to dry naturally. The cooperation is a

benefits. The juicy

selected two rambutan gardens in the

win-win situation for everyone. While BASF benefits from the team members’ unique expertise, they receive a steady, above

Rambutan fruit

average income, health insurance and free meals. The pilot harvest of fruit peels, leaves and seeds took place in 2018. In the same year, BASF initiated an access and benefit sharing (ABS) protocol and entered into a contract with the supplier. Large scale harvesting commenced in 2019.

Built on decades of experience The Rambutan Programme is based on the experience BASF gained from

| JANUARY 2020 | P C Review

SPECIALITY INGREDIENTS Freshly picked oil palm fruits

the Argan Programme it launched in southern Morocco in 2005. The company teamed up with Targanine, a network of six oil processing cooperatives from the region of Agadir, to study the argan tree and how it could use the tree’s oil and by-products. More than 1 000 women from rural communities now work in the cooperatives – a six-fold increase since the start of the programme. The cooperative members market several products, including by-products, botanical and essential oils and bee products. Both parties benefit from the partnership

has committed to spur the production of

– BASF purchases the oil and its by-

sustainable palm oil products. To speed up

products under fair trade conditions,

this process, in 2018 the company initiated

including a non-negotiated premium

a major shift of its speciality portfolio and

price, payment in advance, a fair-

offers exclusively RSPO certified sustainable

trade premium for the oil and long-term

palm-based speciality ingredients for the

forecasts. What’s more, 50 percent of

personal care industry.

Standard. It’s been shown that trained and

the price paid for the pulp is allocated

Apart from a certification system and

certified farmers receive on average a 47

to social funds within the cooperatives.

maximum transparency, social measures

percent higher income than farmers who

The money is used on schemes such as

for local communities, especially

didn’t participate in the programme. The

literacy programmes and health related

smallholders, are key steps towards

first Rainforest Alliance Certified coconut

initiatives. The cooperation also fosters

protecting high carbon stock forests. BASF

oil was produced in 2018 with the support

preservation of the argan forest by the

has partnered with other stakeholders

of this partnership.

population from the region.

along the supply chain to enhance the

A collaborative approach

BASF’s positive impact on both the

living conditions of the people in farming

environment and society is firmly anchored

areas by improving agricultural practices,

in the company’s global sustainability

Being versatile, easy to process and

increasing yields and helping to preserve

strategy with four defined focus areas:

providing yields per hectare that distinctly

forests. Continuous education and

1. climate protection

outreach those of sunflower, rapeseed

technical support help smallholder farmers

2. sustainable product portfolio

and other vegetable oils, palm oil is

implement and maintain sustainable palm

3. responsible procurement

the most widely used vegetable oil. Its

oil practices.

4. engaged employees.

unique chemical properties also make

Projects such as the Rambutan and Argan

it irreplaceable for the oleo derivate

Benefitting coconut farmers

programmes, as well as BASF’s efforts

business. The majority of oil palm products

A similar approach is being utilised for

towards certified sustainable palm and

used by BASF are based on palm kernel oil

the cultivation of coconut palms. BASF

coconut oil prove the strategy to be a

and its derivatives and to a lesser extent

cooperated with Cargill, Procter & Gamble

success. They show it is possible to fulfil

on palm oil. As palm cultivation is linked

(P&G) and the Deutsche Gesellschaft für

consumer demand for products that are

to deforestation, loss of biodiversity and

Internationale Zusammenarbeit (GIZ) in

as good for the planet as are they for the

social conflicts in the producing countries

a development partnership under the

hair and skin – and this innovation goes

– mainly Indonesia and Malaysia – BASF

develoPPP.de programme. The partnership

beyond the lab. By sourcing raw materials

was commissioned by the German Federal

responsibly, BASF is making a sustainable

Ministry for Economic Cooperation and

contribution to rural communities. •

Trained and certified farmers receive on average a 47 percent higher income than farmers who didn’t participate in the programme

Development (BMZ) to establish a certified coconut oil supply chain and improve the livelihood of coconut farmers in the Philippines and Indonesia. Over the past four years, more than

REFERENCE 1. Hernandez-Hernandez C, Aguilar CN, Rodriguez-Herrera R, Flores-Gallegos AC, Morlett-Chavez J, Govea-Salas M, AscacioValdes JA. Rambutan (Nephelium Lappaceum L.): nutritional and

4 100 coconut farmers have been

functional properties. Trends in food science & technology, 85,

trained in Good Agricultural and

201-210, 2019

processing Practices (GAP) as well as Farm Management practices. About 1 600 farmers received additional training and have been certified according to the Rainforest Alliance Sustainable Agriculture

BASF – www.carecreations.basf.com Botanichem www.botanichem.co.za

P C Review | JANUARY 2020 |

PHARMA FOCUS//Lab FOCUS Equipment & Services

Scientific instruments

to help you realise your vision Labotec has partnered with the world’s leading brands to bring home the best quality in analytical equipment. The company offers a range of solutions that meet the current laboratory, analysis and diagnostic needs of the South African pharma industry.

ith the refrigerant regulation

has no breakthrough of organics, silicone

for fluorinated greenhouse

or boron.

gases having been significantly tightened,

PureSure provides customers with the confidence they are receiving the

German company Weiss Technik in

highest guaranteed quality of water at

collaboration with Dresden University of

all times.

Technology, has researched alternatives to R23 refrigerant for use in environmental

Buchi demonstrations

simulation systems.

World renowned for

Weiss Technik is proud to present its

The Purelab Chorus 1 analytical research model from Elga Labwater

commercialising the

newly developed WT69 refrigerant in a

first modern rotary

ClimeEvent climatic test chamber. The

evaporator, Buchi

Weiss simulation systems, including

manufactures state of

the ClimeEvent, are available locally

the art equipment for

from Labotec.

testing and analysis.

The newly released WT69, the pioneering

configuration and adaptability with changing requirements.

Labotec has demo

User protection during precision weighing

result of the refrigerant research, has a

equipment available

Global Warming Potential reduced by 90

in South Africa to give

percent to 1357. This is the ideal solution for

laboratory professionals

use in environmental simulation systems

and analytical experts an

reaching temperatures as low as -70°C with

opportunity to experience

no compromise in terms of performance,

Buchi’s Swiss quality first-hand,

use and cost-effectiveness. The W69

before making an investment decision.

refrigerant reliably delivers comparable

For more information, or to book your

test results and is non-flammable, non-

unique Buchi experience, visit

toxic and non-corrosive.

www.labotec.co.za/book-your-demo or

Captair high precision safety Erlab’s Captair high precision safety weighing cabinet

call the Labotec office on +27 (0)11 3155434.

Ultra pure water and generic medicines

demonstration purposes:

The need to guarantee the delivery

• R-300 Rotary Evaporator, which

The following equipment is available for

of ultrapure type 1+ water reliably

meets the highest expectations in

and consistently is increasing in the

convenience and versatility.

manufacture of generic medicines, as new

• KjelMaster K-375 Distillation unit,

analytical techniques and applications

suitable for potentiometric and

evolve with lower detection limits. Research and development laboratories

colorimetric titrations • E-800 Universal Extractor, suitable for any

require a constant source of high purity

demanding extraction task and which

water to ensure the accuracy of results in

enables simultaneous operation of

their workflow. Elga Labwater’s introduction

different extraction methods

of a fully validated Purelab Chorus 1

• the safe, compact and simple C-850

analytical research model fitted with a

Pure Chromatography unit for any flash

halo flexible dispenser allows scientists to

or prep HPLC application

conveniently dispense water into any size

• NIR Proximate and N-500 for

container and receive real-time feedback

all applications

relating to inorganic water purity and

• L-200 Buchi freeze dryer,

total organic carbon. The PureSure system

which provides a new level of

design optimises consumable usage and

| JANUARY 2020 | P C Review

A ClimeEvent climatic test chamber

convenience and enables individual

weighing cabinets are designed for the safe weighing of hazardous chemical powders and liquids. The

cabinets are designed and produced internationally by Erlab and distributed locally by Labotec. Erlab’s unique flex filtration technology allows any liquid and solid chemicals to be filtered in the molecular and HEPA filters. The cabinet can be fitted with a sensor to detect saturation of the filters of any solvents, acids or formaldehyde detection. It delivers the proper airflow at the face of the enclosure and total filtration of hazardous powders or potent pharmaceutical compounds. The cabinets are ‘smart’ in that safety can be controlled remotely using the eGuard App installed on any desktop or mobile device. When connected, the eGuard App allows the user to monitor one or several devices remotely. Once a product has been registered, the eGuard App can be used to receive safety alerts, view usage statistics and enhance the user’s experience via customised reports. •

Labotec – www.labotec.co.za

grow, nurture, evolve...

Labotec is your guarantee of

HPG16186

WORLD CLASS LAB EQUIPMENT

with South African-based after-sales support and service Visit our website www.labotec.co.za

+27 11 315 5434 | + 27 21 531 7660 | +27 31 566 4870 | sales@labotec.co.za

PHARMA FOCUS//Lab FOCUS Equipment & Services

Analyse, identify and verify in a flash Drug analysis needs to be cost-effective without compromising on accuracy. This is an important principle for routine quality control and the identification of potentially harmful counterfeit medicines. The essence of Metrohm’s spectroscopy solutions are based on this as well as speed, versatility, application focus and compliance.

ear-infrared spectroscopy, or

One example of

NIRS for short, is a useful element

the extraordinary

in the pharma analysis toolbox.

benefits this

It’s a winning choice thanks to

technology brings

the minimal time and labour resources it

is simultaneous

requires, as well as the fully automated

determination

online analyses it offers. NIRS also

of the five active

takes simultaneous analysis of multiple

pharmaceutical

substances in its stride.

ingredients (APIs)

Quality by Design (QbD) and process

used in tablets

analytical technology (PAT) are two

designed to relieve

concepts that have become watchwords

flu symptoms. These

for the US Food and Drug Administration

are paracetamol,

(FDA). These approaches aim to

ascorbic acid,

increase efficiency in the development

dextromethorphan

and production of pharmaceuticals. In

hydrobromide,

features streamline verification routines

QbD’s case, trial and error processes are

caffeine and chlorphenamine

and include an automated training set

replaced with a design, which, from outset, is optimally tuned to the ways in

maleate.This method is validated in accordance with the directives of the International Conference

builder and improved model analysis tools. Soft- and firmware improvements, like a colour coded audit trail with advanced

which the drug will be

on Harmonisation, the

used further down the

European Medicines

easily reference samples even in

line i.e. adapted to suit

Agency, and the

massive databases.

the patient population

Pharmaceutical Analytical

and how it will be

Sciences Group. As a

customisable reports, automated report

result, NIRS can serve as

generation and export, and in-software

an approved alternative to

viewing and printing. Following USP and

administered. Without PAT, the QbD approach could not survive. Process analysis is used to monitor production in real time. It allows alterations to be

the more complex reference method, which requires separate determinations, using HPLC and titration.

made during the process itself in order to

management features, ensure users can

FDA compliance is met with

EP guidelines has never been easier with the new calibrate/verify accessory. This innovative attachment ensures accurate performance of Mira P and the quality of results with a thorough calibration and

achieve the intended quality. It also helps

Portable spectrometry

to improve understanding of the product

For rapid, reliable analysis, Metrohm offers

and process.

Mira P – a Raman solution for the pharma

tested, as expected from Metrohm’s

verification routine. Mira P is IP67 rated and MILSPEC 810G

industry. It brings enhanced resolution,

Five in one

rugged handheld analysers. Its new

new immersion sampling and validation

guided workflow makes Mira P an ideal

Metrohm NIRS is a textbook example

accessories packed in ergonomic features

solution for demanding pharmaceutical

of process analytical technology, with

that improve user experience. This fast,

environments, from verification of morning

numerous publications describing how it’s

easy and accurate device helps users

deliveries to reviewing a day’s audit trail,

implemented in pharmaceutical quality

optimise the inspection of incoming

the device helps increasing the efficiency

control processes – before, during and

goods, formulation verification and

of the typical workflow in the pharma

after production. The peaks and troughs

process monitoring.

manufacturing industry. •

found in NIR spectra conceal a multitude

Mira P and its dedicated software,

of chemical and physical information,

MiraCal P, were developed in

making chemometric methods key to

collaboration with some of the world’s

sifting through and decrypting the info.

leading pharma companies. New

| JANUARY 2020 | P C Review

Metrohm – www.metrohm.com/en-za

Contract manufacturers for the pharmaceutical and complementary medicines markets Hersol Manufacturing Laboratories has been Hersol Manufacturing Laboratories operating for 39 years, and is a key player in the is a registered company specializing complementary medicine manufacturing arena in in manufacturing and packing of South Africa.

complementary medicines for third party

Hersol manufactures widelocal rangeSouth of products in companies withina the African various dosage forms: including tablets – single and market. Founded in 1980, Hersol adheres double layer, coated and uncoated (sugar and film to a Quality Management System which coating), effervescent tablets, capsules, powders, embraces current Good Manufacturing topical preparations such as; creams, gels, ointments Practices in accordance Medicines and lotions, syrups and liquids. with Hersol prides itself onControl quality assured products, which have Council requirements. undergone various compliance checkpoints. Hersol has a highly qualified team who are constantly growing through Hersol’s extensive facility features a fully training and education.

equipped Laboratory to ensure quality

Laminar Flow in Microbiology Laboratory

The new 5 cubicle dispensary and sampling facilities

In of addition to the manufacturing of complementary raw materials and finished products. pharmaceutical products, Hersol also offers Contract It has modern manufacturing facilities Packing. Hersol has a packing department consisting for blending, granulating, compressing & of 13 packing lines employing over 100 people. coating tablets as well as encapsulating Hersol’s packing services extend to the following: Hersol has state of the • capabilities. Containers • art Bottles on-site packing facilities, including • Unit Cartons a recently introduced blister packing • Shrink Wrapping • machine. Blistering In addition, Hersol has facilities manufacture • to Combo Packing and pack syrups, creams,

gels and ointments.

Pack sizes include 30s, 60s,120s,180s and even 200s.

Leadership at Hersol is upheld by a highly

HPLC Testing

Handling of Raw Materials when weighing and dispensing is handled in accordance with Medicines Control Council guidelines

Hersol is proud to note that it has a fully accredited competent Team with Laboratory, splitManagement between Wet chemistry, an vast instrument room withsubject HPLC’s, matter AA, GC and pharmaceutical knowledge Dissolution and DT baths, as well as a comprehensive and experience in staff motivation so as to Microbiological laboratory. All equipment is calibrated achieve a superior product. and checked on a regular basis as per the regulations, and the staff undergo rigorous regular updates and Hersol registered with: accurate and training for is competency, to ensure consistent results are obtained. t South African Medicines Control Council

t South African Pharmaceutical Council

Hersol is registered with: t South African Department of Health • South African Health Products Regulatory Authority Health Product Association – HPA •t South African Pharmaceutical Council •t South African Department Health Cosmetics, Toiletriesofand Fragrances • Health Product Association – HPA Association • Cosmetics, Toiletries and Fragrances Association t FDA Food Facility • FDA Food Facility

Hersol Manufacturing Laboratories (Pty) Ltd tel: +27 11 614 6631/2

fax: +27 11 614 4615

email: enquiries@hersol.co.za admin@hersol.co.za

web: www.hersol.co.za

PHARMA FOCUS//Lab FOCUS//Lab Equipment & Services

An evolution in modular water treatment To produce pharmaceuticals, the water used for manufacturing, cleaning and as a raw material needs to comply with strict regulations regarding purity standards. With its most recent plant expansion, Aspen Pharmacare turned to Veolia Water Technologies for its water treatment and purification needs.

which will produce 9 000ℓ per hour of European and US Pharmacopoeia compliant purified water for the production of clean utilities for Aspen Pharmacare. The pre-treatment skids were designed and produced locally, and commissioning took place in October 2019.

After sales service and tech support Veolia provides continuous operations and maintenance support for all purified water generation and distribution plants installed at Aspen’s Port Elizabeth site.

The Orion purified water generation unit is developed specifically for the pharmaceutical market and compliant with all industry requirements

harmaceutical manufacturing

involves the re-use and recycling of water

facilities require process water that

and wastewater.

meets strict standards of purity.

This includes continual technical support as well as the provision for the supply of spares and annual maintenance servicing when requested. ‘We also have a formal service level agreement with Aspen Pharmacare, with an optional renewal on an annual basis,’

Compliant purified water

Govender adds. According to this SLA,

water purification systems, Veolia helps

In April 2019, the contract was awarded to

Veolia performs a number of scheduled

pharmaceutical companies meet

Veolia Water Technologies South Africa for

equipment inspections through the course

regulatory compliance with a cost-

the design, supply, manufacture, delivery,

of the year to assess the performances

effective, efficient and reliable supply of

installation and commissioning of a new

of the various purified water plants

water. The company recently supplied

Orion 9000MKIII Purified Water Generation

and identify potential operational and

a water purification system to Aspen

Unit complete with pre-treatment skids for

technical issues to be addressed via

Pharmacare’s SVP2 plant expansion in

Aspen Pharmacare’s SVP 2 facility. The

preventative maintenance.

Korsten, Port Elizabeth.

Orion 9000MKIII purified water skid was

Through a range of packaged

Aspen Pharmacare has a long-standing relationship with Veolia Water Technologies South Africa, where the company’s

Pharmaceutical industry water

imported by sea freight from SOLYS UK,

treatment systems from Veolia include

another Veolia business unit.

solutions for purified water, highly

‘This was freighted on completion

purified water, pyrogen-free water, and

Orion purified water systems have been

of the factory acceptance test in mid-

water for injection (WFI). The solutions

supplied to meet the pharmaceutical

August,’ says Vashlin Govender, business

are supplied in South Africa, throughout

manufacturer’s requirements for purified

development manager, Veolia Water

Africa and internationally. •

water. This will be the sixth Orion purified

Technologies South Africa. The Orion

water installation at Aspen Pharmacare’s

9000MKIII E-Series is a hot water sanitisable

Port Elizabeth-based site as part of its

reverse osmosis and CEDI based purified

Stockholm Clean Utilities project, which

water generator with BES duplex softeners,

| JANUARY 2020 | P C Review

Veolia Water Technologies South Africa – www.veoliawatertechnologies.co.za

COMPANY FOCUS

A leader in the field of speciality pharma products Marsing & Co Africa is a full-service agent, importer and distributor of pharmaceutical ingredients and packaging. Its CEO, Rob Springer shared an in-depth account with P&C Review of how the company has evolved over the years. By Abby Vorster

arsing & Co Africa is steeped in history. As a

Marsing & Co Africa’s purpose-built warehousing facility and corporate office, situated at Lanseria Corporate Estate

subsidiary of Marsing & Co, based in Copenhagen,

Denmark, its foundation dates back as far as just after the second world war when John Marsing discovered all the pharmaceutical factories in Europe had been destroyed. Aware of the budding pharma industry in China, he decided to travel to the country to meet with manufacturers of active pharmaceutical ingredients (APIs) and finished products, which he would soon start trading with, in an effort to rebuild the European pharma industry. He established Marsing & Co in 1943 as a trading company for active ingredients for

& Co Africa quickly became a force to

leading branded product. Springer’s team

the pharmaceutical

be reckoned with in the South African

got involved in the request, located a key

and veterinary

pharmaceutical market.

supplier in Dubai – Rak Ghani Glass – and

industries. During

since then, the pharmaceutical glass

Growing alongside its customers

packaging division of the business

expanded the trade worldwide,

While Marsing & Co Africa initially focused

has expanded.

including southern and central

on supplying speciality ingredients to

Africa, where SA Druggists was

the pharmaceutical, nutraceutical and

expansion into plastic tablet jars, now well

the South African agent for Marsing &

animal feed industries, it has diversified

known in the industry as Securitainers.

Co. At the time, Springer was employed

over the years in line with the needs of its

Working in-conjunction with Pulse Plastics,

by SA Druggists as a sales manager.

customers. This has ranged from acquiring

whose factory is a purpose-designed

After the company was acquired by

new suitable suppliers of printed aluminium

cleanroom facility specifically set up

an industrial chemical company, its

and laminate tubes for pharmaceutical

to manufacture of pharma packaging

focus on supplying speciality pharma

ointments and creams, empty gelatine

containers, Marsing & Co Africa

ingredients was reduced, creating

capsules and specialised glass and

introduced its Securitainers to the market

a perfect opportunity for Springer to

packaging for the pharmaceutical industry.

in 2017.

the ’60s and ’70s, he Rob Springer, CEO of Marsing & Co Africa

establish his own business.

This was followed by the company’s

With each of these requests, Marsing & Co Africa has travelled to key markets

A solid and successful team

Springer registered the business in

all over the world, including Asia, India

Above key relationships with customers

June 1994. He says the local company’s

and the Middle East, to locate the right

and principals, Marsing & Co Africa has

success over the past 26 years is

international suppliers of innovative

always put its employees first. Springer

as a result of ‘not only being able

solutions for its customers throughout

says this directive has been central to the

to supply quality chemicals for the

southern Africa.

longevity of the company.

As the CEO of Marsing & Co Africa,

pharmaceutical industry but also being

Another key development for the

‘Our team includes dynamic sales

able to provide economic solutions and

company was its expansion into

coordinators and efficient administrative

the logistics of getting products from

pharmaceutical glass packaging. In 2011,

staff, geared towards fulfilling the

all over the world and delivering them

a South African cough syrup manufacturer

requirements of our customers,’ he

locally’. This was a significant difficulty

approached Marsing & Co Africa to

comments. ‘We encourage all our staff

for the industry in ’90s and why Marsing

source a clear cough syrup bottle for its

to gain knowledge about our customers

| JANUARY 2020 | P C Review

The team at Marsing & Co Africa

We’ve had one resignation in the history of the company

COMPANY FOCUS

and ensures the standard operating procedures of a pharmaceutically

Marsing & Co Africa’s warehousing staff

compliant warehouse are maintained. The company also prides itself on a minimal staff turnover with most of its

says Springer, who is still very hands on in the business. Feeling positive, Springer is certain

employees being long serving. ‘We’ve

and their products, and to keep up to

had one resignation in the history of the

Marsing & Co Africa will continue along

date with industry developments through

company,’ says Springer.

the same lines of success in 2020,

leading publications and regular visits to

Betty Bilankulu, on the housekeeping

expanding enormously as the market

team, has been with the company since the

demands. ‘We are aware of what’s

beginning. Both Scott Watson and Lorenza

coming next and have the enthusiasm

R600 000 on training its warehousing staff,

Ciavaglia, who have been employed since

and knowledge to meet the demand,’

to ensure their complete understanding of

December 1995, remain with the Company

he concludes. •

the newly introduced Granite Warehousing

as sales and finance director respectively.

international exhibitions.’ In 2018, the company spent over

System which incorporates a computerised

‘Scott and Lorenza have been appointed

handling system. This helps the team

shareholders of the business in honour of

comply with Good Warehousing Practices

their outstanding contribution and loyalty,’

Marsing & Co Africa – www.marsing-sa.com

The evolution of innovation for Marsing & Co Africa 1943 John Marsing launches Marsing & Co in Denmark. 1983 Rob Springer is employed as a sales manager at SA Druggists, the agent for Marsing & Co in Denmark.

June 1994 Rob Springer establishes Marsing & Co Africa.

2011 Marsing & Co Africa diversifies again into pharmaceutical glass packaging.

2002 The company establishes an agency agreement with a supplier in India to distribute empty pharmaceutical grade gelatine capsules in the South African market.

1997 Marsing & Co Africa diversifies slightly into printed aluminium tubes, toothpaste, pharmaceutical ointments and adhesives.

2017 Working with Pulse Plastics, the company establishes a pharmaceutically compliant plant and installs machinery and equipment to produce Securitainers.

October 2017 Marsing & Co Africa moves into its new pharma compliant premises in Lanseria Corporate Estate, Johannesburg.

PHARMAKINA S.A

Manufacturer of certified quinine salts from natural cinchona barks since 1949

PHARMAKINA BUKAVU Email : pk.kivu@pharmakina.com Phone +243 998 665 252

www.pharmakina.com

PHARMAKINA KINSHASA Email : pk.kin@pharmakina.com Phone +243 998 855 600

P C Review | JANUARY 2020 |

CLEANROOM TECHNOLOGY & CONTROL

Sterilisation solutions designed to provide competitive advantage Telstar offers one of the most advanced and quality alternatives worldwide in the field of sterilisation equipment under CGMP guidelines. For the pharmaceutical and biotechnological industries, it specialises in designing and producing integrated equipment for sterilisation, freeze-drying, containment and clean air.

nown as one of the 10 major

The fully automated process

suppliers to the global

integrated in the SteriDelta

pharmaceutical industry, Telstar

system overcomes the

has made a solid commitment

limitations of a manual

to the continuous development of technologies for the life sciences sector. Its experience is endorsed by of more than 1 700 installations of integrated process equipment and systems over the past 50 years. Telstar has a consolidated activity in the

DID YOU KNOW?

and pharmaceutical freezedrying applications,

designed to ensure an Telstar’s integration of an aseptic and efficient automated system increases loading and unloading production. This performance and productivity in the overall production process process, which requires included the SteriDelta by up to 40 percent. It further an extended cooling sterilisation system and provides an average reduction of 15 percent of the duration of phase for the product to a new multi-purpose the sterilisation cycle. Energy reach a temperature to modular autoclave consumption savings of up to 20 percent are permit manual handling. range designed to also proven. The automation on the other minimise footprint

engineering and construction of complete

hand enables unloading at

turnkey pharmaceutical and biotech

higher temperatures providing higher

production facilities, critical installations,

efficiency with an average reduction

cleanrooms and R&D laboratories. Its

of 15 percent of the duration of the

Plus, a new compact steam sterilising

portfolio also includes GMP consultancy

sterilisation cycle, saving up to 20

autoclave with GMP design. The

for regulatory compliance and IT solutions

percent in energy consumption.

autoclave includes hinged front-facing

for regulated processes and logistics management.

The robotised sterilisation system is

while maximising maintenance access. It also showcased the Telstar Sterimega

access panels, which open completely

designed to be highly versatile and can

to provide full access to the technical

gradually be implemented based on the

area of the equipment.

Automated sterilisation system

particular needs of greenfield or existing

The company offers one of the most

units. Engineered to sterilise large batches,

A global footprint

advanced and quality alternatives

the equipment includes a Telstar Scada

Headquartered in Terrassa, Barcelona,

worldwide in the field of sterilisation

supervisory, control and data acquisition

Spain, Telstar has a workforce of 900

equipment under cGMP guidelines. The

system providing full production line

people. The company invests three

SteriDelta sterilisation system integrates

traceability, helping to store, retrieve and

percent of its turnover in research and

robotised processing for preparing

transfer process knowledge.

development and in the innovation of

the product arriving from one or more

technologies and equipment. It operates

filling lines to be loaded directly into the

New solutions on show

in over 100 countries and has four

steriliser chamber without any human

At CPhI and P-MEC India, which took

production plants, seven technology

intervention. The automated system is

place in Delhi from 26 to 28 November,

centres, 12 consultancy and engineering

engineered to cover whole operational

Telstar showcased the latest solutions in

services centres and commercial offices

phases, connecting the sterilisation

isolation technology systems, sterilisation

located worldwide. Telstar’s manufacturing

process from the filling line to the

plants are situated in Spain, China and the

inspection line.

United Kingdom. The company has had presence in India since 2007, while the Telstar brand is now represented in the Asia region by three specialised production plants and engineering centres in India, China and Bangladesh. In South Africa, Telstar is represented by MGSA Projects. •

Telstar sterilisation autoclave

| JANUARY 2020 | P C Review

MGSA Projects – www.mgsaprojects.co.za Telstar – www.telstar.com

CLEANROOM TECHNOLOGY & CONTROL

One method set to harmonise disinfectant validation

With the number of standardised test methods available globally, disinfectant efficacy testing can be a daunting task as there are numerous factors to consider. Ecolab’s Validex harmonised method is set to reduce this complexity for end users and help them gain greater efficiency in their disinfectant efficacy validation processes.

armonisation is currently lacking

factors into consideration to develop

in the methods generally

Validex, a harmonised method that

used in the EU and the US for

supports efficacy studies conducted

disinfectant efficacy testing, with

by end users. Further supporting data

individual pitfalls and unique challenges

is also available on the performance of

characteristic of all the existing standards.

Ecolab disinfectants on a range of typical

These standards are also not specifically

surfaces and isolates relevant to the

set out for cleanroom disinfectants which

cleanroom environment.

is why adaptations to reflect a cleanroom

This additional supporting information

Using accredited laboratories, it also eases navigation through disinfectant

environment should be considered with

serves as an extension of end users’ own

efficacy testing, helping end users

the support of guidance documents such

validation data, minimising the cost

comply with the standards required for

as (USP) 40-NF35 Chapter <1072>.

and resources required for their efficacy

cleanroom decontamination. •

studies. This harmonised ‘one method’

Clear, sensible and reproducible

can give companies a transferable

Ecolab, represented in South Africa by

platform to achieve replicable results

Basan, has taken all the aforementioned

between laboratories and countries.

Basan – www.basan.co.za Ecolab – www.ecolab.com

P C Review | JANUARY 2020 |

CLEANROOM TECHNOLOGY & CONTROL

A handy guide to validating high purity water systems High purity water is critical to pharmaceutical processing. Validation of the systems used to produce high purity water and close adherence to the SOPs are essential to maintaining the quality and integrity of the water generated. Kenneth Amaral of Fabtech outlines points to consider in order to increase the odds of successful validation.

ater is the most widely

and quality of water during operations

• operating procedures

used raw material

and maintaining this according

• maintenance instructions and records

in the production of

to specific written operating and

• training of personnel

pharmaceuticals, and in

maintenance procedures.

• environmental records

some products, like parenterals, it’s a

The following factors are involved in

• plant inspection documentation.

vital element. Water is also used to clean

proving the validation of high purity

Once validation is complete, an effective

vessels and systems used to manufacture

water systems:

standard operating procedure (SOP)

pharma products.

• engineering design

is finalised, with the assurance that the

• operating procedures and acceptable

system can consistently produce water

A unique aspect of high purity water used in the pharma industry is that it’s possibly the only element, which, as a rule, must be produced by the drug manufacturers themselves as it’s not available in ready to use form. Irrespective of the system used to

ranges for control parameters • maintenance procedures to accomplish it • the system has to be designed,

according to specification and over long periods. If any deviations from the SOP are observed, it’s necessary to determine the change and impact on the whole

installed and successfully tested in all

system and carry out revalidation based

operating conditions

on the change and impact.

generate high purity water, regulatory

• variations in daily, weekly and annual

Any validation protocol must include

guidelines around the world mandate

usage patterns must be validated.

the elements outlined above. However,

validation of the system. Validation

A validation report is written at the

the validation process is long and often

is necessary to monitor system

conclusion of equipment, instrumental

small details can be overlooked.

performance including that of storage

and operational qualification and

and distribution systems. It ensures

at the completion of the validation

UV Lights

the system is operating within design

protocol. This report serves as the primary

One of the most commonly overlooked

parameters along with the consistent

document during inspection by the

considerations is UV lights. When UV

production of water of a desired quality.

regulator and as a reference document

lights pass through microorganisms,

Validation also prevents unacceptable

if any changes are made to the system

they inhibit reproduction and disrupt

microbial, chemical and physical

and revalidation is needed.

the DNA of the cell. A UV lamp must function at optimum efficiency at all

impurities from being generated during water generation, storage

Documentation required

times to maintain the quality of UV rays

and distribution.

During validation, the following

and keep microbial contamination

documentation is required:

in check.

It allows manufacturers to prove the performance of processes or systems under all conditions, encountered during future operations. This is achieved by consistently producing the same quantity

• verification of design documentation

analysed before and after UV exposure

and functions and specifications

to determine whether microbiological

of functions

A reverse osmosis system installed within a pharmaceutical processing plant

42 | JANUARY

2020 | P C Review

Water samples from test ports are

including a description of installation

contamination is present. UV systems

CLEANROOM TECHNOLOGY & CONTROL Biofilm formation

RO, EDI and UF water treatment system designed and constructed by Fabtech

A well-known problem that plagues the

Chemical cleaning and sanitisation

water industry is biofilm. This is formed if

Sanitising is done in a two step process,

water is stagnant even for a short while.

which involves the use of an acidic

Bacteria, microbes, pathogens (E. coli

reagent such as citric acid to remove

and salmonella) and other organisms

inorganic foulants. This is followed by

present in water attach themselves to

a high pH reagent such as sodium

the inner surface of pipelines and lead

hydroxide, which helps to remove

to the formation of biofilms. The initial

organic foulants. The reverse osmosis

biofilm formation is a slimy, hydrophobic

system is sanitised using formaldehyde

layer that enables microorganisms to

or hydrogen peroxide and then

remain attached to the surface. Because

thoroughly rinsed until all chemicals are

of the presence of bacteria, biofilm

flushed out of the system.

Buyer’sguide also damages pipes. Bacteria produce

microorganisms; they contribute to their

hydrogen sulphite, which reacts with iron

and sanitisation must be carried out at

reduction by two to three logs, with the

in pipes and causes corrosion.

regular intervals, using a schedule based

THE

are never absolute in the reduction of

reduction sometimes around the level of 100cfu per millilitre.

The removal of biofilm is both expensive

This process of chemical cleaning

on the level of microbial concentrations

and challenging, making prevention the

and samples collected from the

preferred route by any means. To control

second pass reverse osmosis permeate

procedures, UV lamps must be replaced

microbial growth, the reverse osmosis

outlet. As per the SOP, cleaning and

every six months as quartz in most

system must be cleaned and sanitised

sanitisation should be carried out every

lamps accumulates impurities in raw

regularly, particularly first pass reverse

10 to 15 days. A detailed log should be

water. The ballast that provides power

osmosis. Cleaning before sanitisation

maintained along with periodic test

to the UV lamp should also be changed

helps disrupt the biofilm that protects the

results of an increase in microbial growth

every two to three years. Intensity

bacteria and does not allow it to come in

of permeate water. •

meters are a must as they assist in the

contact with the sanitising reagent. It will

maintenance of the UV lamp and

also remove foulants that react to and

As per standard validation

2017/2018

Fabtech – www.fabtechnologies.com

Buyer’sguide chemically deplete the sanitising reagent.

THE

with validation.

2018/2019 2019/2020

The directory for manufacturers of food, beverages, pharmaceuticals, cosmetics, toiletries, packaging and the printing industry

Available online: www.thebuyersguide.co.za Buyers Guide 2018.indd 1

2018/05/07 3:09 PM

P C Review | JANUARY 2020 |

COLOUR COSMETICS

Be inspired to create the perfect look With the start of a new decade comes a new aesthetic. Inspiring a fresh set of colours and looks, Karen Maier, head of performance materials for Merck South Africa, explores makeup for the modern woman in the company’s Autumn/Winter and Spring/Summer 2020 colour forecasts.

he Radical Aesthete is

radiant pigments for an ethereal

fearless. There are four distinct colour

a woman who does not

holographic effect.

stories in this season with a common

compromise. She looks for

thread evident in each look – this is the

Real yet romantic

power of one’s ability to turn your dreams

harmony, sharp and precise lines

While the realms of the mermaids and

into reality.

and absolute contrasts. Her beauty is

unicorns are enticing, women still need

uncompromising; navy and black add

to prove themselves in the real world.

woman who seeks a new spirituality

strength and depth to the eyes and

Taking charge in boardrooms and

while staying true to her core beliefs.

the lips, while graphic lines are used to

running large corporations, an elegant

She looks for authenticity in her daily life,

great effect. Contrast and interesting

and noble style is more natural and

embracing a minimalist approach. Her

powerful and fundamental

textures complete the narrative – lacquered, ultra-glossy, velvety and metallised textures all have their role to play in this tale of black. For each strong woman immersing herself in the dark black narrative, there is a dreamer – a Punk Princess – who is a committed leader among the light hearted. The Punk Princess dreams of grunge romanticism and street poetry while bathing herself in iridescent and pastel

Metallised, ultra-glossy shades feature on lips, pampered and cared for as part of an everyday beauty routine

tones. This woman strives for a happy

controlled for the Amazon Rider. We see

and healthy glow against the harsh

shades of terracotta, metallic bronze

winter, focusing on the complexion and

and noble ochre contrasted by a pop

embracing radiance and illumination.

of fiery red. The look is healthy, silky and

In her life, fun comes from creating

luminous with a gold mascara lending

the perfect magical look with ultra-

true refinement. Metallised, ultra-glossy

Spiritual Muse is a contemporary

colours are soft and the textures natural. Her complexion is at the forefront of her makeup with softly applied powdery textures to soften the features while her eyes are embellished with gold and white. Apricot, terracotta and henna tones are used on the cheeks, lips and eyes.

shades feature on lips, pampered and cared for as part of an everyday beauty

CREATE PRODUCTS WITH IRRESISTIBLE DAZZLE New from Merck, Ronastar Dazzling Lights is a body coloured pigment that features a golden, living sparkle effect. This unparalleled shade of gold underscores eccentric statements with its neo-baroque touch. It offers pure elegance and a shift towards extreme glamour mode. The smooth substrate creates crystalline and light-catching effects, thanks to an ingenious coating technology that enables formulas to produce even more sparkle from small particles. It also offers a low heavy metal content, is highly stable in formulations and provides a smooth skin feeling.

| JANUARY 2020 | P C Review

routine, offering a glamorous contrast to the overall understated aesthetic. Muse Spirit is the last Autumn/ Winter 2020 look, based on theatrical being living in a romantic, mystical dreamscape. She embraces ultra-

The glamorous Shining Queen

sophisticated glamour with playful

abandons restrictions in her approach

colour compositions and ultra-sensual

to beauty, sparkling throughout her days

femininity. This woman plays with

and nights. She is hedonistic, seeking

texture and contrasts, combining

pleasure and fun with the ability and

velvety, satiny finishes with a pop of

charm to turn each moment into a party.

fuchsia, or blending metallic, iridescent

This is a passionate and intense look,

effects with just a touch of gold to

with pops of vermillion and magenta

create fascination.

paired with shades of a tropical sunset. Magnetic blue hair mascara lends

Sparkling and spiritual

a touch of electricity to this queen’s

Merck’s Spring/Summer 2020 forecast

crowning glory. Her body sparkles with

calls for action to be bold, intense and

the sunlit tones of a body highlighter,

COLOUR COSMETICS The Invincible Woman has a strong survival spirit. She turns to science and bio-hacking to ensure her skin can withstand the modern urban lifestyle. High performing masks, saturated in active ingredients, serums and essences treat and protect her against the onslaught of the life she chooses to lead. Her preference is for sticky, rough or granular textures and the depth of nature informs her colour choices. Amphibian and swamps greens, marine algae and spirulina tones form a dark iridescent palette, conjuring up a chameleon-like beauty with a surprising use of blues and greens on the lips. Whatever the season and while her lips are bathed in sensual pink gold.

Merck’s colour forecast wall featuring sculptures produced using makeup samples that were on display at incosmetics Global 2019

Gentle versus strong

whichever end of the beauty spectrum a woman may find herself in 2020, she has the power to plot her own destiny, determining which dreams

To counterfoil the shine, Committed

mauve, menthol green and soft blue. She

to follow and how to express her own

Visionary is a gentle and devoted

crafts a fresh, natural look using artificial

unique beauty. •

woman, bathed in positive soft pastels,

hues. For the lips and cheeks there are

wearing creamy eye-shadows and a

shades of soft pink and golden apricot

tender nurturing primer. Her colours are

while nails are adorned with neo‑caramel.

Merck – www.merckgroup.com

P C Review | JANUARY 2020 |

COLOUR COSMETICS

Pure solutions for natural beauty products As the food and cosmetics industries converge to similar more natural and sustainable models, they’re becoming increasingly intertwined. Sensient Cosmetic Technologies explores the use of fruit and vegetable extracts to create superfood infused colour cosmetics with an uplifted brand energy.

atural is not a trend – it’s a

Table 1: SCT4173 XFine Natural Lip Glosses

fundamental requirement. Going beyond the

Phase

basic natural origin of

ingredients, consumers expect more

from cosmetics brands. People are focusing on labels, ingredients and

4173-1 %w/w

4173-2 %w/w

42.00

4.00

23.50

25.00

Tocopheryl Acetate

0.50

Natpure XFine Beetroot BR312 (or)

Beta Vulgaris (Beet) Root Juice (and) Citric Acid (and) Ascorbic Acid (and) Maltodextrin

5.00

Natpure XFine Radish RR311 (or)

Raphanus Sativus (Radish) Root Extract (and) Citric Acid (and) Maltodextrin

Natpure XFine Potato SP313 (or)

Ipomoea Batatas Tuber Extract (and) Citric Acid (and) Acacia Senegal Gum (and) Maltodextrin

Natpure XFine Turmeric TU114

Turmeric Oleoresin (and) Gum Acacia (and) Maltodextrin

Ingredient

INCI

Castor Oil

Ricinus Communis (Castor) Seed Oil

Thixcin R PC

Trihydroxystearin

Castor Oil

Ricinus Communis (Castor) Seed Oil

Castor Oil

Glyceryl Isostearate (and) Isostearyl Alcohol (and) Butyrospermum Parkii (Shea) Butter (and) Euphorbia Cerifera (Candelilla) Wax (and) Brassica Campestris (rapeseed) Sterols

Vitamin E Acetate

production methods, embracing niche ways of living and eating. The movement is about more than

just food – it’s a seismic shift in why, where and how people consume. Such as the ‘local is lekker’ and ‘love or buy local’ movements, embracing nature is here to stay. Our throwaway culture is also becoming a contentious issue and consumers

are looking for sustainable, ethical and responsible ways

4173-3 4173-4 %w/w %w/w

5.00

to conserve the planet’s resources. They are affiliating themselves

Beauty has opted for phyto-pigments

beauty brands, Sensient Cosmetic

with companies that share their

instead of artificial ones to colour its

Technologies offers a new generation

cultural and ideological values.

eyeshadows and lip products. The

of powdered natural extracts based on

These consumers are hungry for

eyeshadows are packed with vitamins

vegetable juices. These extracts have

natural beauty and consider natural

C and E and coloured with Eclipta daisy

proven ‘care’ benefits and provide

ingredients to be healthier. As a result,

and moringa phyto-pigments. Cape

pleasing colours in colour cosmetics.

food textures and ingredients derived

lilac and aubergine phyto-pigments are

from plant and vegetable sources are some of the best ways to make the connection. Yet there can be no compromise on efficacy.

used to colour the lip products. Rituel de Fille’s Forbidden

Extracts for edible cosmetics Natpure XFine Powder Complexes from Sensient Cosmetic Technologies

Lipstick is both

are water soluble and oil dispersible

bold and

where they remain stable with

cosmetics brands on the

daring. This

temperature. They are produced by

market include Raw Cosmetic,

and the rest

entrapping the vegetable juices in

of the brand’s

a carrier to form a powder complex

colour cosmetics

of coloured actives suitable for use

Leading natural colour

which takes natural formulations a step further by including extracts of acai and goji berries and kale and Kakadu plum in its

are said to be handcrafted with natural

in colour cosmetics and skin and hair care products. The complexes

extensive range of makeup. Skin Food

ingredients and free from phthalates,

are also easy to transport and store,

Fresh Fruit Juice Extraction Tint and

synthetic dyes and fragrances.

thanks to their powdered form.

Blush features natural fruit extracts and

For South African colour cosmetics

gives vivid colour with no caking. Juice

brands inspired by these global natural

| JANUARY 2020 | P C Review

The range includes Natpure XFine Potato SP313, Natpure XFine Beetroot

COLOUR COSMETICS

BR312, Natpure XFine Radish RR318,

alcohol) acts as a pigment,

Natpure XFine Radish RR311, Natpure

bringing high colour

XFine Spirulina SL615 and Natpure XFine

strength to lipsticks, skin

Turmeric TU114. See Table 1 for the

cosmetics and compact

formulation guide for a range of natural

powders. Less than one

lip glosses featuring these extracts.

percent of Natpure XFine in a lip

The Natpure XFine extracts are

To prove the superior benefits of these new powdered extracts, Sensient Cosmetic Technologies

balm provides a slight colour on mass

tested Natpure XFine Potato SP313

preservative free and ideal for

and upon application while 10 to

against a leading benchmark

natural formulations, particularly

20 percent of the powdered extract

ingredient, each formulated at

those products positioned as edible

in a lipstick gives intense colour

20 percent in a lipstick.

cosmetics. Due to the brightly coloured

and coverage.

nature of the vegetable juices, the

Skin applications of both lipsticks showed a higher colour strength for

extracts are great alternatives to

Multifunctional benefits

the one with Natpure XFine Potato

natural dyes, as they lend bright and

Natpure XFine Powder Complexes

SP313. In terms of homogeneity, the

homogeneous colour to

also have antioxidant and healing

lipstick formulated with the benchmark

the skin and hair.

properties, may prevent skin ageing

ingredient became heterogenous after

For example,

and UV-induced skin damage,

one and four applications while the

Natpure XFine

scavenge free radicals, improve

lipstick formulated with Natpure

Beetroot BR312

skin’s moisture content and

XFine Potato SP313 remained

used at

texture, and they are even

homogeneous after

0.1 percent in

known to have antibacterial,

two applications.•

water (pH4), acts as a dye to provide a naturally coloured product. One

anti-inflammatory and wound healing benefits. When used with polyphenols,

percent of the same powered extract

the powder complexes create an

in octyldodecanol (a common fatty

optimised carrier system.

Sensient Cosmetic Technologies – www.sensient-cosmetics.com

NATPURE® Xﬁne RED RADISH

Contact our team : nicola.barnardmarais@sensient.com www.sensient-cosmetics.com

P C Review | JANUARY 2020 |

ASSOCIATION NEWS// NEWS

Cheers to the summer holidays

he Society of Cosmetic

at The Steak & Grill Co. in Morningside,

beach attire, sun hats and flipflops

Chemists, Coschem hosted its

Durban, for an unforgettable dining

and to accessorise with pool noodles

Johannesburg and KwaZulu-Natal

experience. Steak & Grill Co. is the only

and mini inflatables such as lilos and

year-end luncheons on 14 and

steakhouse in South Africa housed in

tubes. The events offered guests an

22 November respectively. The Joburg

a national monument. Both year-end

opportunity to network with old and new

event took place at Casalinga Restaurant

functions were based on a summer

faces from the cosmetics and personal

in Muldersdrift, Gauteng while members

holiday theme and guests were

care industry, while enjoying a delicious

from the KwaZulu-Natal chapter met

encouraged to wear brightly coloured

meal together. •

HIGHLIGHTS FROM COSCHEM’S JHB YEAR-END FUNCTION

2020 DATES TO DIARISE 3 February – Coschem Cosmetic Science Course Prize Giving Dinner 6 February – Coschem AGM and Networking Cocktail Party 26 February – Sustainability Seminar 19 May – Coschem Annual Golf Day 9 to 10 September – Coschem Annual Scientific Conference, HPCI Expo and Gala Dinner

| JANUARY 2020 | P C Review

SNAPS FROM COSCHEM’S KZN YEAR-END FUNCTION

ASSOCIATION NEWS// NEWS

SAAFFI seminar to focus on sustainability

The 2020 event, the 18th SAAFFI seminar, will be held on Thursday, 19th March 2020 at the Altron (Bytes) Conference Centre in Midrand, Gauteng. The full-day program features an impressive line-up of speakers, a hands-on workshop, an inspiring motivational presentation and a networking cocktail event.

or the last 18 years, the the South

factors that synergise towards making

African Association of the Flavour

the future of the industry in Africa, a

& Fragrance Industry (SAAFFI)

particularly exciting one. Themed ‘taboo

seminar has attracted around

or not taboo – trends that are smoking

Dr Berangere Magarinos-Ruchat, global

200 key personnel drawn from a wide

h(p)ot, the 2019 seminar examined

head of sustainability of Firmenich,

range of companies in the flavours and

issues that were once taboo which have

Geneva has confirmed she will present

fragrances industry and from FMCG

become trendy and in demand. Of

at the seminar.

companies, as well as academics,

course, the Cannabis debate

consultants, regulators and raw material

featured strongly.

suppliers. The day offers a valuable

Breaking news is the confirmation that

Other confirmed presentation topics include flavour and fragrance trends, waste management – is it a load of

learning and networking opportunity

Expert speakers confirmed

garbage, saving 1 200 species of bees

and addresses relevant topics of interest

Themed ‘save the planet – wake up,

– the buzz of the industry, re-usable

to all industry players.

grow up and speak up’, the 2020

packaging – should we discard it?

Confronting tricky business issues

seminar will address issues of relevance

SAAFFI represents all aspects of this

has always been one of the guiding

to the flavour, fragrance and FMCG

fascinating industry. It unites the industry

principles of the organising committee.

industries around environmental and

across non-competitive issues, freeing

The 2018 seminar themed ‘motion of no

sustainability threats to the Earth’s

up individual organisations to grow

confidence – promoting a bright African

continued existence. It will also look at

their business. •

future for the flavour and fragrance

the industry’s role in alleviate

industry’, examined many of the positive

these threats.

For more information, and to book for the event, visit www.saaffi.co.za/events.

CELEBRATING A YEAR IN REVIEW On 28 November, Pharmaceutical & Cosmetic Review and SA Food Review joined SAAFFI for its year end function at Thunder Walker, located on Ghandi Square. Hosted by JoburgPlaces, this incredible venue is steeped in history and offers the most amazing African cuisine in one of Joburg’s oldest yet Michael Gristwood, SAAFFI’s executive director presenting a Maryke Foulds, Candida Giambostill operational buildings. special certificate to Kruger, Abby Vorster and Anita Raath In addition to celebrating another Rudy MacLean of New Media successful year for the association and members, the event honoured Symrise’s Rudy MacLean, who has led SAAFFI as the A bird’s eye view of Summer House chairman of its management committee for the past 14 years. We were treated to a meze migrant feast in the upstairs section of Summer House, which was built in 1904. For dessert, we headed downstairs to Zwipi Underground – an exceptional dining space within the historic United Safety Deposit bank vault. Thank you to SAAFFI for hosting such a memorable event. Summer House, where SAAFFI’s guests enjoyed Ghandi Square, home to the famous statue of Mahatma Gandhi

the delicious starter and main course

P C Review | JANUARY 2020 |

Tea time Crossword puzzle 1

6 7

Across

Down

1. Capital of Spain (6)

1. Monarchy on the French Riviera (6)

3. New York lake, sounds

2. Saltwater lake on the border

tranquil (6)

between Israel and Jordan (4,3)

7. Falls and honeymoon resort (7) 4. Italian isle (5) 11

15 18

16 19

8. Austrian province (5)

5. Texas city (6)

9. Washington’s largest city (7)

6. Island country south of Sicily (5)

10. Country, initially (3)

8. Famous fountain in Rome (5)

11. Augusta is the state capital (5)

12. Currency of Nigeria (5)

13. Florida resort (5)

14. Funchal is the capital of this

18. Australian capital, initially (3) 21

20. Reykjavik is the capital (7)

21. Europe’s longest river (5)

TO ADVERTISE IN Anita Raath Sales executive

+27 (0)82 976 6541

Carla Melless Sales executive

+27 (0)83 260 6060

Càndida Giambò-Kruger Sales executive

+27 (0)71 438 1918

| JANUARY 2020 | P C Review

Atlantic island (7) 15. Riga is the capital of this Baltic country (6)

22. Australian river (7)

16. Tenerife’s volcanic peak (5)

23. South American river (6)

17. Capital of the Czech Republic (6)

24. Capital of Zimbabwe (6)

19. City in north-eastern Oklahoma (5)

ADVERTISERS INDEX Canbigold............................................. OBC.........www.canbigold.com Chemgrit Cosmetics................................22.........www.chemgritcosmetics.co.za Christo Coetzee Attorneys..........................7.........www.christocoetzeelaw.co.za CTFA..........................................................8.........www.ctfa.co.za Danlink Ingredients..................................25.........www.danlink.com Designa Plastics...................................... 19.........www.designaplastics.co.za Hersol Manufacturing Lab........................35.........www.hersol.co.za IMCD SA .............................................. OFC.........www.imcdgroup.com Intertek Deutschland................................26.........www.intertek.com Labotec ..................................................33.........www.labotec.co.za Marsing SA .............................................37.........www.marsing-sa.com Merck......................................................45.........www.merck.co.za Messe Düsseldorf.................................... 13.........www.germanchamber.co.za MGSA Projects......................................... 41.........www.mgsaprojects.co.za Pharmakina SA........................................39.........www.pharmakina.com Rotolabel.................................................21.........www.rotolabel.co.za Sensetek .................................................29.........www.sensetek.co.za Sensient Cosmetic Technologies..............47.........www.sensient-cosmetics.com South African Trade Promotions ..............28.........John.t@satp.co.za Vantage Specialty Chemicals ..................27.........www.vantagegrp.com

Online

INDUSTRY WEB REVIEW ESSENTIAL SPECIALISED PRODUCTS

COSCHEM

Supplier of cosmetic and personal care ingredients.

Visitors to the Society of Cosmetic

Ingredients include; Bioferments, Botanical Extracts, Delivery Systems,

Chemists’websitewillfindinformation

Enzymes,FunctionalActives,Silicones,Emollients,Emulsifiers,Meadowfoam

on membership, educational

Seed Oil & Derivatives, Abyssinian and other Oils, Shea and other Butters,

programmes (specific details

Aliphatic Hydrocarbons, Lanolin & Derivatives

pertaining to the Cosmetic Science Training),aswellasthesociety’sobjectivesofpromotingprofessionalismand

Tel: 010 595 9690

higher technical skills in the cosmetics and toiletries industries.

Email: info@esp-sa.co.za www.esp-sa.co.za

www.coschem.co.za

M&L LABORATORY

DALGEN

M&L Laboratory Services (Pty) Ltd, provides clients with an

Dalgen is a leading supplier of high-quality glass containers,

extensive array of analytical capabilities. M&L renders testing

plastic containers, closures and packaging accessories.

services to the Food & Beverage, Mining, Environmental, Water & Pharmaceutical sectors. M&L is an ISO 17025 accredited facility, licenced by the Medicine Control Council (MCC) & endorsed by the World Health Organisation (WHO). Our schedule of accreditation can be viewed via www.sanas.co.za

Tel +27 (0)31 569 4288 Fax +27 (0)31 569 4294 Email sales@dalgen.co.za or purchasing@dalgen.co.za www.dalgen.co.za

Mobile: +27 (0)76 114 9420 Office: +27 (0)11 661 7900 Email: keshav.beachen@za.bureauveritas.com

FORMPAK

BRB SILICONES

For over 40 years Formpak has supplied specialised processing,

The largest independent producer in the world of

packaging and printing machinery to the pharmaceutical, cosmetic, plastic, glass, chemical, food and dairy industries.

Tel +27 (0)11 828 8870/1/2 Fax +27 (0)11 828 8880 Email haase@formpak.com or service@formpak.com www.formpak.com

H&R AFRICA Your world's leading supplier of top quality mineral oils, petroleum jellies, and paraffin waxes, as well as customer-specific formulations. If you want to come out top you have to partner with the world's top leaders. Connect with us to see how we can connect your business to the world.

113 Trinidad Road, Island View Bluff, Durban 4052, South Africa Tel: +2731 466 8700 Fax: +2731 466 8716/7 Email: sasales@hur.com Website: www.hur.com

core and specialty silicones, BRB offers a wide range of solutions with unique benefits in skin, body and hair care and colour cosmetics.

www.brb-international.com

QUANTUM COLOURS SA Your No. 1 industry leader for the most comprehensive ranges of both synthetic and natural colours – used in food, pharmaceutical, cosmetic and industrial applications. Tablet coatings – manufactured, supplied and marketed globally under our trade name PHARMASPEC™ - FC

www.quantumcolours.com Manufactured, marketed and distributed under licence of SPECTRATEC INC. CANADA Canada . South Africa . Ireland . Germany . Australia . UK

Pharmaceutical & Cosmetic Review January 2020

Articles inside

Pure solutions for natural beauty products

A handy guide to validating high purity water systems

Scientific instruments to help you realise your vision

Formulating sustainable products

A route to uniting researchers and traditional knowledge holders