Olerup SCORE bennefits

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HELMBERG-SCORE updated due to the HLA nomenclature changes ™

A brief description.

4.001T / 2010


HELMBERG-SCORE™ 4.001T

Here are your new benefits: Due to the HLA nomenclature changes, the Helmberg SCORE™ is now updated with focus on userfriendliness and simplicity. In the new version, 4.001T, an application of new HLA Nomenclature enables instant switching between the old and the new nomenclature any time for each typing. Typing specific preferences for old/new nomenclature are stored, and a master switch is available for each front end to use the old or new nomenclature. This way, you still have the freedom to choose as you like depending on your own needs. Once you have downloaded the new version, you will find that the new features of the Helmberg SCORE™ have been developed so that the conversion from the old to the new nomenclature will be made as easily as possible for the laboratory staff. The following new benefits are to be found:

 Conversion/teaching tool for information of old/new allele nomenclature.  Linking back and forth between old and new.  Complete list for each locus both for old and new alleles.  Filter functions to select a group of old or new alleles and display the equivalents.  Combined view of frequency status, old /new name, serological equivalent, G-name, P-name. The software design is integrated with Olerup SSP®, and is to be used with the Olerup SSP® products. Basically, you will find that the new interface remains almost the same as you and your staff, are used to seeing in your daily work. There is no need for extra education or changes in routines. The new features are simple, and will be learned as the user tries out the options. Please take a moment to look through the following basics.

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Starting: This is the new Helmberg SCORE™ start screen. The buttons activating the different functions are displayed on the left hand side. To create a patient record, click on “Patient/sample”.

The new 4.001T version

Previous version

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The Nomenclature switch: This option is the most essential feature of the new 4.001T version. Since the nomenclature transition will create different needs during the change over, we give you the option to choose in every single situation. The typing specific preferences for old/new nomenclature are stored in the software. You can go from old to new, as well as new to old. Or to User Defined Nomenclature and reverse. The instant switch is in the upper left corner.

Click for Old Nomenclature

Click for User Defined Nomenclature

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Click for New Nomenclature

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Creating a patient record: Start Helmberg SCORE™. The new patient file-card template appears for entry of individual Patient as well as Sample data.

The new 4.001T version

Previous version

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To create a new patient, click on “Patient/sample” and confirm by clicking on “Main”. Enter the following: Family name /first name and sample ID or Patient ID and sample ID.

The new 4.001T version

Previous version

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Entering results: To create a gel click on “Gel” in the menu bar and “New” on the left side of the Helmberg SCORE™ screen. The gel data window opens.

The new 4.001T version

Previous version

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Click on “New”. Helmberg SCORE™ opens a new window for you to select an Olerup SSP® typing kit (e.g. DR low resolution kit) from the list of imported Olerup SSP® kits.

The new 4.001T version

Previous version

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Gel Screen: Click “Insert typing kit” to integrate additional Olerup SSP® high resolution kit(s) into the gel and follow the procedure mentioned on page 9.

The new 4.001T version

Previous version

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The space on the gel picture is limited to 96 positions. If all positions of the gel are covered – click on “New” to start a new gel.

The new 4.001T version

Previous version

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Analysis screen: Click “Analysis” to calculate the results. The check box “nomenclature 3.x” allows the flexible application of the new Allele Nomenclature, i.e. instant switch between old and new nomenclature. If the check box is checked, the result will be displayed according to the new nomenclature. If the check box is unchecked: the result will be obtained according to the old nomenclature. Click “Analyse” to start the calculation.

The new 4.001T version

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The new 4.001T version

Previous version

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Analysis Screen – High resolution result: presentation of data If “nomenclature 3x” is checked, the high resolution result will be displayed according to the new nomenclature. If “nomenclature 3x” is unchecked, a high resolution result will be displayed according to the old nomenclature.

High resolution result with NEW nomenclature

High resolution result with OLD nomenclature

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Main screen with total information Click on “Main� to receive patient file-card with total information displayed for patient/sample.

The new 4.001T version

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Print functions: Click “Print” to print typing results from the patient file-card. There are different print options.

The new 4.001T version

Previous version

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Print out – results displayed according to new nomenclature.

Print out – results displayed according to old nomenclature.

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New features in 4.001T: Conversion and teaching tool Tool contains a complete list for each locus for old alleles and new alleles. A drop down box allows the entering (or scrolling) of the new/old allele name for each locus to obtain the new/old allele name. A complete list of all alleles for each locus is displayed, with frequency status, old name, new name, serology, G-group/name and P-group/name.

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Typing kit import The Typing kit import function: reduction to kits that are currently in inventory. The filter function allows kits to be listed based on allele groups. The sorting function allows sorting according to typing kit name, batch or expiry date. Automatic cleaning of database of unused typing kits before import

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Typing kits – information screen Click on “Typing Kits” to activate “Typing construction set”. Tool to be used to check all existing primers and mixes for specificity and localization.

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Registration: You laboratory will be defined by �Lab Code�. When registering, please fill in all field and accept the Terms & Conditions. Once you have completed the firm and sent the registration, you will recieve an e-mail with User Name and Password to the e-mail addres stated in your registration. Other users from the same laboratory will be able to register in a shorter way, using the built in data from the first registration.

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Login: Once you have completed the registration, and for the coming updates, you will need to sign in using the User Name and Password given at the first visit.

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CORE

HELMBERG-S

4.001T / 2010

Xim harum nobis

sitia doloresto

tem quamet

od maio cum,

eum faccus,

si autate nis aute

cumquam, exerum

et laborehenis

ipiet

Distributed by:

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Manufactured by:

OLERUP GmbH Address: Loewengasse 47/6, 1030 Vienna, Austria Orders and support: support-at@olerup.com Tel: +43-1-710 15 00. Fax: +43-1-710 15 00 10

Olerup-SSP® AB Address: Hasselstigen 1 SE-133 33 Saltsjöbaden, Sweden E-mail: info-ssp@olerup.com Tel: +46 8 717 88 27. Fax: +46 8 717 88 18

OLERUP Inc Address: 901 S. Bolmar St., Suite R West Chester, PA 19382 Orders and support: info.us@olerup.com Tel: 1-877-OLERUP1. Fax: 610-344-7989

www.Olerup SSP®.com

www.olerup.com

Olerup-SSP®® AB is ISO 9001:2008 and ISO 13485:2003 certified. Olerup-SSP®® AB is IVD certified in accordance with the requirements of the IVD Directive 98/79/EC. Olerup-SSP®® HLA Typing Kits are FDA cleared and licensed by Health Canada.

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