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Background Research has shown that 5a-hydroxy-laxogenin is a spirostanic analogue of brassinosteroid. Athletes has been interested in the 5a-hydoxy-laxogenin benefits It possesses an anabolic/androgenic activity that is very comparable to those of the most efficient anabolic substances, anavar. It is still without side effects of liver toxicity or the likelihood of testing positive for steroids. Athletes Have been interested in the 5a-hydroxy-laxogenin benefits such as muscle enhancement, liver non toxicity, Increased Protein Synthesis and Decreased Stress Hormone ( Cortisol ) A report from Russian research desk reveals that 5α -Hydroxyl laxogenin has the tendency to accelerate weight gain in rats by increasing the weight of some organs like liver, heart, kidneys, musculus tibiliasis anterior and also increasing the total amount of protein contents as well. The numerated changes above become much severe with the study substance giving to young animals. It has been shown that 5α-Hydroxy laxogenin can be used by the athletes as it enhances the strength for 3-5 days and that of muscle increase in 3-4 weeks. The mechanism of the muscle growth and accelerated repair is as a result of enhanced protein synthesis by over 200%. Further research on the molecule reveals that it can also be used to balance the cortisol response which is the backbone for the recovery and reduction of muscle wasting.
What is 5a-hydroxy laxogenin? 5a-hydroxy 5-Alpha-Hydroxy-Laxogenin, is a naturally occurring plant based steroidal sapogenin found in Smilax Sieboldii – a plant related to asparagus that is native to China and Japan. 5-Alpha-Hydroxy-Laxogenin is a member of a group of 40 plant-derived compounds, known as brassinosteroids, which have a similar structure to animal steroid hormones. Plant steroids work through a completely different pathway than human steroid hormones. They attach to the cell surface in animals, which sets off a signal inside of the cell and activates a protein, known as AKT1 or protein kinase B, that enhances cellular metabolism and reduces muscle breakdown. Supplementing 5-Alpha-Hydroxy-Laxogenin may, therefore, help support muscle building, thermogenesis, enhance physical performance, and support quick recovery from exercise when used in conjunction with a healthy diet and exercise program. As opposed to human steroids, 5-Alpha-Hydroxy-Laxogenin will not be converted to the more powerful male sex hormones (testosterone and dihydrotestosterone) in the body, nor does it run the risk of raising estrogen or causing unwanted effects like sex hormone imbalances or liver and kidney damage.
5-alpha-hydroxy-laxogenin benefits - What does 5a-hydroxy laxogenin do? Let's move on to why you started researching 5a-hydroxy laxogenin in the first place - the benefits. As you might already know, this compound is extremely popular amongst bodybuilders and other athletes. You'll find many positive user experiences of those who have used it to help enhance performance.
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Phcoker
Xuchang shangke Chemical Co., Ltd
www.phcoker.com
While the data and studies are near impossible to find, based on anecdotal experience, 5a-hydroxy laxogenin could potentially benefits with: - 5a-hydroxy laxogenin benefits user by increasing protein synthesis by over 200% which allows the user to accelerate muscle growth and recovery . -Provides cortisol support, thus allowing your body to recover fast and reduces muscle breakdown (muscle wasting). -Athletes claim to have seen strength increases in 3-5 days, and muscle mass increases in 3-4 weeks. -Does not alter the users natural hormonal balance (does not affect testosterone levels and does not convert into estrogen or cause the body’s natural estrogen to increase) -Does not show up on narcotic or anabolic drug screens or drug tests (can be used by Athletes in NCAA and other major league sports)
Is 5a-hydroxy laxogenin the same as Laxogenin? While chemically very similar and also in the name and even both being found in the same class of plants smilax. But 5a-hydroxy laxogenin’ & ‘Laxogenin’ are not the same product. Please take a look at the image below. the top one is laxogenin and the bottom is 5a-hydroxy laxogenin.
For this reason, it's imperative to buy your 5a-hydroxy laxogenin powder from a manufacturer that provides
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Email: info@phcoker.com
Phcoker
Xuchang shangke Chemical Co., Ltd
www.phcoker.com
Certificate of Analysis and/or uses the HPLC-test method in which is guaranteed to be pure 5a-hydroxy laxogenin powder.
Is 5a-hydroxy laxogenin a prohormone 5a-hydroxy laxogenin shouldn’t be mistaken for a prohormone, as it has a different mechanism. It works uniquely and is said not to cause any side effects when taken. As you probably already know, there’s a lot of positive user experiences on this compound. But, it’s essential to know that there are no human studies to back up the effectiveness of this plant steroid.
Is 5a-hydroxy laxogenin safe Is 5a-hydroxy laxogenin banned by FDA? No, but it is added to FDA Dietary Supplement Ingredient Advisory List. 5a-hydroxy laxogenin is on the FDA Dietary Supplement Ingredient Advisory List, but it does not necessarily indicate that the FDA has determined that the ingredient is unsafe; it means FDA is taking steps to further evaluate the ingredient. 5a-hydroxy laxogenin safety is always being concerned by athletes and those who want to gain muscle. Whether 5a-hydroxy laxogenin supplement can be use? Given the fact that 5a-hydroxy laxogenin does not affect hormones, it has been deemed safe for anybody, including women. This also means that there is no reason to restrict the duration of supplementation with this product. Meaning it can be safely used for as long as desired, regardless of your body composition goals. However, 5a-hydroxy laxogenin has also been shown to help the body maintain and support healthy cortisol levels which can have a negative side effect on muscle gain and fat loss when they increase excessively.
Best 5a-hydroxy laxogenin powder manufacturer | Where to buy 5a-hydroxy laxogenin powder? Since laxogenin has gotten extremely popular over the last year, more and more supplement companies have started adding it to their product lineup. When you search up laxogenin , you will find a ton of supplement being sold containing it. Most of them talk about its anabolic benefits. But please keep in mind that Laxogenin is not 5a-hydroxy laxogenin. the mass market supplement buyers will not have a clue the differences between the two. You will be thinking that you want to buy single ingredient 5a-hydroxy laxogenin powder only. On top of that you want to find the best 5a-hydroxy laxogenin manufacturer. Lucky for you we did that job for you. Our 5a-hydroxy laxogenin raw powder is the best ingredients, the purity is no less than 99%, plus, it’s on sale right now. We have 5a-hydroxy laxogenin powder sell in bulk and wholesale, if you want to buy it from the best 5a-hydroxy laxogenin powder supplier you can here.
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Email: info@phcoker.com
Xuchang shangke Chemical Co., Ltd
Phcoker
www.phcoker.com
References: [1] The power of hyphenated chromatography-Time of flight mass spectrometry for unequivocal identification of spirostanes in bodybuilding dietary supplements. Avula B, Chittiboyina AG, Bae JY, Haider S, Wang YH, Wang M, Zhao J, Deuster PA, Khan IA. J Pharm Biomed Anal. 2019 Apr 15;167:74-82. doi: 10.1016/j.jpba.2018.12.045. Epub 2019 Feb 1. PMID: 30753977 [2] Synthesis of brassinosteroids analogues from laxogenin and their plant growth promotion. Wang Q, Xu J, Liu X, Gong W, Zhang C. Nat Prod Res. 2015;29(2):149-57. doi: 10.1080/14786419.2014.968151. Epub 2014 Oct 14. PMID: 25311045 Steroidal saponins from the rhizomes of Smilax sieboldii. Kubo S, Mimaki Y, Sashida Y, Nikaido
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Ohmoto
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Phytochemistry.
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10.1016/0031-9422(92)83296-b. PMID: 1369386 [Laxogenin, a new steroidal sapogenin isolated from Smilax sieboldi Miq]. AKAHORI A, YASUDA F. Yakugaku Zasshi. 1963 May;83:557-8. PMID: 14041495 Studies on the steroidal components of domestic plants. XLVII. Constituents of the stem of Smilax sieboldi Miq. (1). The structure of laxogenin. Okanishi T, Akahori A, Yasuda F. Chem Pharm Bull (Tokyo). 1965 May;13(5):545-50. doi: 10.1248/cpb.13.545. PMID: 5867711
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